Product Datasheet

YWHAQ Antibody

Catalog No: #32715

Orders: [email protected] Description Support: [email protected]

Product Name YWHAQ Antibody

Host Species Rabbit

Clonality Polyclonal

Purification Antibodies were purified by affinity purification using immunogen.

Applications WB IHC IF

Species Reactivity Hu Ms Rt

Specificity The antibody detects endogenous level of total YWHAQ .

Immunogen Type Recombinant Protein

Immunogen Description Recombinant protein of human YWHAQ.

Target Name YWHAQ

Other Names 1C5; HS1; 41701;

Accession No. Swiss-Prot:P27348NCBI ID:10971

SDS-PAGE MW 28KD

Concentration 1.0mg/ml

Formulation Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02%

sodium azide and 50% glycerol.

Storage Store at -20°C

Application Details

Western blotting: 1:500 - 1:2000

Immunohistochemistry: 1:50 - 1:200

Immunofluorescence: 1:50 - 1:100

Images

Western blot analysis of extracts of various cell lines, using YWHAQ antibody.

Address: 8400 Baltimore Ave. Suite 302 College Park MD 20740 USA http://www.sabbiotech.com 1 Immunohistochemical analysis of paraffin-embedded human stomach cancer using YWHAQ antibody at dilution of 1:200 (400x lens).

Immunofluorescence analysis of HeLa cell using YWHAQ antibody. Blue: DAPI for nuclear staining.

Background

This gene product belongs to the 14-3-3 family of which mediate by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 99% identical to the mouse and rat orthologs. This gene is upregulated in patients with amyotrophic lateral sclerosis. It contains in its 5' UTR a 6 bp tandem repeat sequence which is polymorphic, however, there is no correlation between the repeat number and the disease.

Note: This product is for in vitro research use only and is not intended for use in humans or animals.

Address: 8400 Baltimore Ave. Suite 302 College Park MD 20740 USA http://www.sabbiotech.com 2