Catalog # Aliquot Size

I836-40N-50 50 µg

Recombinant Human IFNA4 Recombinant human expressed in E. coli cells

Catalog # I836-40N Lot # G3211-51

Product Description Purity

Recombinant Human IFNA4 was expressed in E. coli cells. The Recombinant Human IFNA4 protein accession number is P05014 resolved on a 15% SDS-PAGE gel under reducing conditions Aliases and stained with Coomassie Brilliant Blue G-250

Interferon alpha-4B, alpha-76, Interferon alpha-M1 Approx. MW 19.6 kDa Endotoxin Level

<1.0 EU/µg of recombinant protein as determined by the LAL method

Storage and Stability

The lyophilized protein is stable for at least one year from date of receipt at -70°C. Upon reconstitution, this can be stored in working aliquots at 2° - 8°C for one month, or at -20°C for six months, with a carrier protein without detectable loss of activity. Avoid repeated freeze/thaw cycles.

Scientific Background

All known subtypes of IFN- alpha show the same antiviral Recombinant Human IFNA4 Recombinant human protein expressed in E. coli cells antiparasitic, antiproliferative activities. IFN-alpha forms are produced by monocytes/macrophages, lymphoblastoid cells, Catalog Number I836-40N fibroblasts, and a number of different cell types following Specific Lot Number G3211-51 induction by viruses, nucleic acids, glucocorticoid hormones, and Purity 95% low-molecular weight substances. All IFN-alpha subtypes possess Stability 6 mos. at –20oC from date of a common conserved sequence region between amino acid shipment positions 115-151 while the amino-terminal ends are variable. Storage & Shipping The lyophilized protein is stable for at Many IFN-alpha subtypes differ in their sequences at only one or least one year from date of receipt two positions. IFN-alpha and IFN-beta are thought to bind to the at -70°C. Upon reconstitution, this same receptor. Signal transduction mechanisms elicited after cytokine can be stored in working binding of IFN-alpha to its receptors involves tyrosine aliquots at 2° - 8°C for one month, or at -20°C for six months, with a carrier phosphorylation (see also: PTK; protein tyrosine kinase) of various protein without detectable loss of non-receptor tyrosine kinases belonging to the Janus kinases. activity. Avoid repeated freeze/thaw cycles.

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FOR IN VITRO RESEARCH PURPOSES ONLY. NOT INTENDED FOR USE IN HUMAN OR ANIMALS.