Authors: Pallavi Subhraveti Ron Caspi Quang Ong Peter D Karp An online version of this diagram is available at BioCyc.org. Biosynthetic pathways are positioned in the left of the cytoplasm, degradative pathways on the right, and reactions not assigned to any pathway are in the far right of the cytoplasm. Transporters and membrane proteins are shown on the membrane. Ingrid Keseler Periplasmic (where appropriate) and extracellular reactions and proteins may also be shown. Pathways are colored according to their cellular function. Gcf_900172385Cyc: Pseudooceanicola marinus CECT 7751 Cellular Overview Connections between pathways are omitted for legibility. Anamika Kothari an amino an amino an amino phosphate an amino acid acid acid an amino D-alanyl- ammonium ammonium glycine betaine glycine betaine acid acid glutathione ammonium glutathione D-alanine uracil gly gly predicted predicted predicted predicted ABC ABC ABC ABC RS06780 RS16840 RS11635 RS20760 RS12325 RS11650 RS00300 RS15300 RS10600 RS08850 RS17755 RS03585 RS04475 RS06250 RS11565 RS12605 RS02280 RS11735 RS11720 RS12810 RS11855 RS14620 RS19800 RS14965 RS00475 RS06305 RS06255 RS18110 RS04470 RS07735 RS04430 RS12725 RS16295 RS03715 RS04825 RS16040 RS19025 RS08055 RS08440 RS11865 RS18670 RS20740 RS16010 RS15435 RS13110 RS06735 RS08600 RS02385 RS06090 transporter transporter transporter RS16550 transporter of an of an of an of phosphate amino acid amino acid amino acid an amino an amino D-alanyl- ammonium ammonium uracil glycine betaine glycine betaine glutathione ammonium glutathione acid acid D-alanine gly gly phosphate an amino an amino an amino acid acid acid

RS01335 RS13880 Nucleoside and Nucleotide Degradation Secondary Metabolite Degradation tRNA processing Macromolecule Modification a ribonucleoside a (3R)-3- a (3R)-3- a (3R,11Z)-3- 1-[18- purine nucleotides degradation II (aerobic) γ superpathway of L- Amino Acid Biosynthesis D-arabitol degradation a purine 4-( -L-glutamylamino)butanoate a purine a purine succinyl-CoA a 3-oxo acid MEP CTP 2',3'-cyclic hydroxydocosanoyl- hydroxyglutaryl- hydroxyoctadec- D-glycerate hydroxyoleyl]- L-histidine biosynthesis L-lysine biosynthesis I superpathway of branched chain amino acid biosynthesis L-arginine biosynthesis I (via L-ornithine) superpathway of L- Aminoacyl-tRNA Charging pyrimidine deoxyribonucleotides ribitol degradation arsenate isoleucine biosynthesis I superpathway of L-methionine a polycistronic ribonucleoside adenosylcobinamide ribonucleoside ribonucleoside phosphate dephosphorylation gamma-glutamyl-gamma- acyl CoA:acetate/ bifunctional 2-C- multifunctional 2',3'- [acp] 3-hydroxyacyl-[acyl- [acp] methyl ester3-hydroxyacyl-[acyl- 11-enoyl-[acp]3-hydroxyacyl-[acyl- 2-hydroxy-3- 2-lyso- biosynthesis (by sulfhydrylation) threonine biosynthesis tRNA precursor 5'-triphosphate purine-nucleoside purine-nucleoside RS10075 RS14225 NTP D-arabinitol bifunctional aminobutyrate hydrolase: 3-ketoacid CoA methyl-D-erythritol cyclic-nucleotide 2'- carrier-protein] carrier-protein] carrier-protein] oxopropionate phosphatidate oxaloacetate PRPP pyruvate tRNA charging AMP D-ribitol phosphorylase: phosphorylase: asp thr Glu glutaminyl-tRNA gln pyrophosphohydrolase: arabitol adenosylcobinamide PSM7751_RS11895 transferase 4-phosphate dehydratase FabA: dehydratase FabZ: dehydratase FabA: reductase: aspartate oxaloacetate oxaloacetate PSM7751_RS15470 PSM7751_RS15470 phosphodiesterase/ aspartate kinase: biosynthesis via dehydrogenase: ribitol dehydrogenase: kinase/ gamma-glutamyl-gamma- subunit beta: PSM7751_RS04765 aminotransferase: ATP acetolactate synthase aspartate multifunctional 2',3'- PSM7751_RS17605 cytidylyltransferase/2- 5'-nucleotidase/ PSM7751_RS16475 PSM7751_RS09885 PSM7751_RS16475 PSM7751_RS16060 threonine bifunctional ornithine transamidation PSM7751_RS18595 PSM7751_RS04515 adenosylcobinamide- aminobutyrate hydrolase: purine-nucleoside purine-nucleoside PSM7751_RS06210 1-[18- PSM7751_RS15760 phosphoribosyltransferase: large subunit: aspartate aminotransferase: arg cyclic-nucleotide 2'- nucleoside triphosphate C-methyl-D-erythritol 3'-nucleotidase: 3-hydroxyacyl-[acyl- 3-hydroxyacyl-[acyl- 3-hydroxyacyl-[acyl- 2-hydroxy-3- aspartate kinase: dehydratase: acetyltransferase/ arginine--tRNA ligase: a tRNA precursor D-xylulose D-ribulose phosphate PSM7751_RS01925 phosphorylase: phosphorylase: hydroxyoeoyl]- RS20075 RS13665 PSM7751_RS02225 PSM7751_RS20090 aminotransferase: PSM7751_RS15760 exoribonuclease: phosphodiesterase/ pyrophosphohydrolase: 3-oxoacid CoA- 2,4-cyclodiphosphate PSM7751_RS01510 carrier-protein] carrier-protein] carrier-protein] oxopropionate aspartate PSM7751_RS07775 PSM7751_RS17475 N-acetylglutamate PSM7751_RS10240 an L-arginyl- Glu with a 5' extension guanylyltransferase: PSM7751_RS08565 PSM7751_RS08565 2-[18-hydroxy- ATP [+ 2 isozymes] PSM7751_RS15760 aspartate PSM7751_RS15440 IMP PSM7751_RS19910 ribulokinase: α-D-ribose- transferase: synthase: dehydratase FabZ: dehydratase FabA: dehydratase FabZ: reductase: aminotransferase: L-aspartyl- synthase: [tRNA Arg ] 5'-nucleotidase/ xylulokinase: PSM7751_RS08395 4-aminobutanoate Glu ribose-1-arsenate a purine base 2',3'-cyclic-nucleotide lioleoyl]-sn phosphoribosyltransferase threonine aminotransferase: and a long 3' trailer a tRNA precursor with dCTP dCMP a purine adenosyl- a purine base PSM7751_RS14425 PSM7751_RS03965 PSM7751_RS09885 PSM7751_RS16475 PSM7751_RS09885 PSM7751_RS06130 PSM7751_RS08285 4-phosphate aspartate PSM7751_RS17610 a tRNA Arg 3'-nucleotidase: PSM7751_RS04540 PSM7751_RS04510 1-phosphate a 2,3,4-saturated 4-(cytidine 5'- 2'-phosphodiesterase: a (2E)- a (2E,11Z)- tartronate -glycerol 3- regulatory subunit: (S)-2-acetolactate ammonia-lyase: PSM7751_RS08285 a 5' extension and ribonucleoside cobinamide succinate a (2E)-docos- aminotransferase: an L-glutamyl- PSM7751_RS01510 GMP IMP dehydrogenase: D-xylulose D-ribulose 3-oxoacyl-CoA diphospho)-2-C- PSM7751_RS12635 enoylglutaryl- octadeca-2,11- semialdehyde phosphate asp PSM7751_RS02230 aspartate- PSM7751_RS16445 N-acetyl-L- a short 3' extension 5'-diphosphate phosphate a ribonucleoside 2-enoyl-[acp] FlgI ketol-acid PSM7751_RS08285 asp [tRNA Gln ] PSM7751_RS10035 deoxyuridine 5-phosphate 5-phosphate methyl-D-erythritol [acp] methyl ester dienoyl-[acp] semialdehyde glutamate 3'-phosphate 1-(5-phospho- (2Z)-2-aminobut- adenosine multifunctional 2',3'- IMP dehydrogenase: 5'-triphosphate aspartate kinase: reductoisomerase: aspartyl/ ribonuclease D: ribonuclease P β-D-ribosyl)-ATP dehydrogenase: 2-enoate asp acetylglutamate aspartate kinase: PSM7751_RS08780 nucleotidohydrolase: PSM7751_RS16060 PSM7751_RS07315 PSM7751_RS17725 ribonuclease D: protein component: cyclic-nucleotide 2'- PSM7751_RS19505 (2R)-2,3- cys glutamyl-tRNA PSM7751_RS08380 aspartate kinase: phosphoribosyl-ATP kinase: PSM7751_RS16060 ribonuclease D: PSM7751_RS10680 phosphodiesterase/ all trans-decaprenyl- guanosine a (3R)-3- aspartate kinase: cysteine--tRNA ligase: amidotransferase PSM7751_RS20735 adenosine deaminase: a nascent peptidoglycan an N-modified D-arabinofuranose 4-phosphooxy- (2R,3S)-3- diphosphatase: aspartate- dihydroxy-3- PSM7751_RS20785 aspartate kinase: 5'-nucleotidase/ XMP [+ 2 isozymes] Aldehyde Degradation γ ethylnitronate D-glycerate D-mannitol RS12875 PSM7751_RS07775 PSM7751_RS05225 subunit A: gatA PSM7751_RS10680 ribonuclease D: ribonuclease PH: PSM7751_RS01675 dUMP with (L-alanyl- -D- 2-methoxy-6- a purine 2'- 5-phosphate 2',3'-cyclic L-threonine hydroxyicosanoyl- isopropylmalate PSM7751_RS06455 semialdehyde methylbutanoate PSM7751_RS16060 sulfate PSM7751_RS07775 an L-cysteinyl- 3'-nucleotidase: dUTP lipid II (meso aminoacyl-[tRNA] N-acetylglutamyl- Cys PSM7751_RS17725 glutamyl-meso-2,6- nitronate 1,4-benzoquinol deoxyribonucleoside 3-deoxy-8- monophosphate 4-hydroxythreonine- [acp] 3-isopropylmalate 2-hydroxy-3- NAD(P)- L-aspartyl- dehydrogenase: 2-iminobutanoate aspartate kinase: [tRNA ] [+ 4 isozymes] PSM7751_RS17410 diaminopimelate bifunctional aminoacyl-tRNA 2',3'-cyclic-nucleotide 3-hydroxyacyl-[acyl- β 2,3-dihydroxy- Cys a tRNA precursor with PSM7751_RS01510 multifunctional 2',3'- methylglyoxal degradation I purine-nucleoside dependent alcohol 1-(5-phospho- - sulfate phosphate L-aspartyl- a tRNA diaminopimeloyl- monooxygenase: hydrolase: phosphooctulonate 2'-phosphodiesterase: 4-phosphate carrier-protein] dehydratase oxopropionate 4-phosphate PSM7751_RS14860 isovalerate PSM7751_RS07775 an L-glutaminyl- a short 3' extension inosine containing) demethylmenaquinone phosphorylase: D-ribosyl)-AMP cyclic-nucleotide 2'- 5-hydroxy-CTP 5-hydroxy-CMP D-alanyl-D-alanine) monofunctional PSM7751_RS12195 synthase: dehydrogenase PdxA: large subunit: reductase: dehydrogenase: adenylyltransferase N-acetyl-gamma- 4-phosphate [tRNA Gln ] methyltransferase/2- PSM7751_RS15865 PSM7751_RS12635 dehydratase FabA: L-aspartate- dehydratase: guanosine phosphodiesterase/ pentapeptide biosynthetic PSM7751_RS15470 PSM7751_RS20630 PSM7751_RS19625 PSM7751_RS12430 PSM7751_RS06130 PSM7751_RS13945 RS06185 aspartate- phosphoribosyl-AMP L-aspartyl- small subunit: glutamyl-phosphate a tRNA precursor methylglyoxal 2-nitropropane methoxy-6-polyprenyl-1,4- aminoacyl-tRNA multifunctional 2',3'- PSM7751_RS16475 semialdehyde PSM7751_RS14755 aspartate- purine-nucleoside 5'-nucleotidase/ S-methyl-5'- peptidoglycan purine-nucleoside 2-dehydro-3- 4-hydroxythreonine- NAD(P)- semialdehyde cyclohydrolase: 4-phosphate PSM7751_RS20640 reductase: with a 5' extension ribonuclease D: lactoylglutathione a nascent peptidoglycan dioxygenase: benzoquinol methylase: hydrolase: cyclic-nucleotide 2'- 3-hydroxyacyl-[acyl- 3-isopropylmalate 2-hydroxy-3- 3-methyl-2- semialdehyde ribonuclease PH: phosphorylase: purine-nucleoside 3'-nucleotidase: thioadenosine transglycosylase: phosphorylase: deoxyphosphooctonate 4-phosphate dependent alcohol dehydrogenase: PSM7751_RS20025 4-hydroxy- 2-oxobutanoate PSM7751_RS04995 PSM7751_RS10680 lyase: with (L-alanyl-γ-D- PSM7751_RS19145 6-methoxy-3-methyl-PSM7751_RS13915 PSM7751_RS13715 phosphodiesterase/ carrier-protein] dehydratase oxopropionate 1-(5-phospho-β-D-ribosyl)- oxobutanoate aspartate- APS dehydrogenase: gln PSM7751_RS17410 PSM7751_RS08565 phosphorylase: PSM7751_RS01510 degradation II PSM7751_RS17830 [unspecified α PSM7751_RS08565 PSM7751_RS19505 tetrahydrodipicolinate N-acetyl-L- ribonuclease D: PSM7751_RS15695 di-trans,octa-cis glutamyl-meso-2,6- an N-modified an uncharged 2-deoxy- - aldolase: dehydrogenase PdxA: dehydratase FabZ: small subunit: reductase: dehydrogenase: semialdehyde PSM7751_RS19505 Storage Compound Biosynthesis ribonuclease: PSM7751_RS08565 S-methyl-5'- degradation nitrite acetaldehyde 2-all-trans-decaprenyl- 5'-nucleotidase/ aspartate- 5-[(5-phosphoribosylamino) synthase: acetolactate synthase glutamate 5- PSM7751_RS17725 purine-nucleoside [+ 2 isozymes] -undecaprenyl amino acid tRNA D-ribose 1- a purine base PSM7751_RS16340 PSM7751_RS16185 PSM7751_RS12425 PSM7751_RS04765 PSM7751_RS04545 RS07405 dehydrogenase: adenylyl- an L-glutaminyl- PSM7751_RS20735 xanthosine thioadenosine (R)-S- diaminopimeloyl- products] 1,4-benzoquinol 3'-nucleotidase: 3-amino-1- PSM7751_RS09885 (2S)-2- tartronate aldehydo- semialdehyde methylideneamino]imidazole- PSM7751_RS15060 2-isopropylmalate branched-chain large subunit: semialdehyde aspartate- phosphorylase: purine-nucleoside methylthioadenosine diphosphate phosphate a (2E)-icos- PSM7751_RS19505 sulfate kinase: [tRNA Gln ] lactoylglutathione D-alanyl-D-alanine) KDO-8P PSM7751_RS01510 hydroxyacetone D-mannose 4-carboxamide (2S,4S)-4- synthase: amino acid PSM7751_RS20090 hydrogencarbonate acetylornithine semialdehyde polyhydroxybutanoate biosynthesis PSM7751_RS15470 phosphorylase: phosphorylase: isopropylmalate semialdehyde dehydrogenase: PSM7751_RS20645 a tRNA Gln pentapeptide 1-phosphate 2-enoyl-[acp] 1-(5-phosphoribosyl)-5- hydroxy-2,3,4,5- PSM7751_RS15960 aminotransferase: [+ 2 isozymes] aspartate- transaminase: dehydrogenase: PSM7751_RS15470 PSM7751_RS07795 hydroxyacylglutathione 3'-GMP PSM7751_RS14860 carbamoyl [(5- phosphoribosylamino) tetrahydrodipicolinate [+ 2 isozymes] PSM7751_RS17935 semialdehyde PAPS PSM7751_RS09545 PSM7751_RS14860 hypoxanthine purine-nucleoside hydrolase: L-aspartate- (S)-2-aceto-2- phosphate synthase acetyl-CoA 5-MTR-1-P RS10510 methylideneamino]imidazole- 4-hydroxy- dehydrogenase: guanine phosphorylase: PSM7751_RS09750 semialdehyde branched chain hydroxybutanoate large subunit: N-acetyl-L- L-aspartate- 4- carboxamide isomerase: tetrahydrodipicolinate (2S)-2- PSM7751_RS14860 phosphoadenosine acetyl-CoA PSM7751_RS15470 undecaprenyl- a very-long- an [apo BCAA 2-methoxy-6-all (4S)-4-hydroxy-2- adenosine a 3-(all-trans a (3R)-3- a [lipoyl-carrier amino acid ketol-acid PSM7751_RS02315 ornithine semialdehyde (R)-lactate L-arabinitol reductase: isopropylmalate phosphosulfate an uncharged tRNA diphospho-N- (S)-3-methyl-2- dehydrogenase trans-heptaprenyl- 2',3'-cyclic -polyprenyl) hydroxypimeloyl- protein]-N 6 -[(R) 3',5'-ADP homoserine PSM7751_RS06430 aminotransferase: reductoisomerase: L-aspartate- Glu acetyltransferase: xanthine dehydrogenase: purine-nucleoside chain fatty acid oxoheptanedioate dATP dehydrogenase: PSM7751_RS15610 reductase: carbamoyl acetylornithine L-arginine biosynthesis II (acetyl cycle) homoserine acetylmuramoyl- UDP-N-acetyl- long-chain fatty oxopentanoate E2 protein] N 6 1,4-benzoquinol NAD(P)-dependent 2,4-dihydroxyhept- monophosphate benzene-1,2-diol [acp] methyl ester -dihydrolipoyl]- phosphoribulosylformimino- 3-isopropylmalate PSM7751_RS08460 PSM7751_RS07315 semialdehyde PSM7751_RS15020 PSM7751_RS18945 guanine deaminase: phosphorylase: bifunctional 2',3'-cyclic-nucleotide bifunctional 3- 3-hydroxyacyl-[acyl- 3'(2'),5'-bisphosphate deacetylase: dehydrogenase: γ α branched-chain alcohol dehydrogenase: NTP PSM7751_RS00700 (S)-2,3,4,5- dehydratase PSM7751_RS11310 phosphate synthase an L-glutamyl- [+ 6 isozymes] Metabolic Clusters [+ 3 isozymes] PSM7751_RS17025 PSM7751_RS08565 L-alanyl- -D- -D-glucosamine acid--CoA ligase: -lipoyl-L-lysine demethylmenaquinone 2-ene-1,7-dioic 2'-phosphodiesterase: demethylubiquinol 3- carrier-protein] L-lysine dihydrolipoyl nucleotidase: RS06705 AICAR-phosphate (R)-2,3-dihydroxy- homoserine PSM7751_RS04605 PSM7751_RS00700 pyrophosphohydrolase: small subunit: [tRNA Glu ] glutamyl-L-lysyl- undecaprenyldiphospho- PSM7751_RS14560 alpha-keto acid PSM7751_RS13945 acid aldolase: dehydrogenase: tetrahydrodipicolinate small subunit: 3-methylpentanoate phosphoadenosine N-acetylglutamyl- methyltransferase/2- PSM7751_RS12635 O-methyltransferase/ dehydratase FabZ: PSM7751_RS20650 L-homoserine dehydrogenase: [+ 4 isozymes] glu muramoylpentapeptide beta-N- dehydrogenase PSM7751_RS17605 PSM7751_RS12425 val phosphosulfate PSM7751_RS07275 phosphate a tRNA acetoacetyl-CoA N-end rule pathway I (prokaryotic) pyruvate D-alanyl-D-alanine [+ 6 isozymes] methoxy-6-polyprenyl-1,4- NAD(P)-dependent PSM7751_RS00815 2-polyprenyl-6- PSM7751_RS09885 PSM7751_RS05125 imidazole glycerol 2,3,4,5- 2,3-dihydroxy-3- PSM7751_RS00700 N-acetyl-gamma- L-homoserine xanthine ditrans,octacis- multifunctional 2',3'- 3'(2'),5'-bisphosphate protein S-nitrosylation and denitrosylation acetylglucosaminyltransferase: subunit E2: alcohol dehydrogenase: 2,4-dihydroxyhept- nucleoside triphosphate tetrahydropyridine- 3-isopropylmalate reductase: carbamoyl glutamyl-phosphate acetoacetyl- undecaprenyldiphospho- a very-long-chain an [apo BCAA dehydrogenase benzoquinol methylase: cyclic-nucleotide 2'- hydroxyphenol 3-hydroxyacyl-[acyl- dihydrolipoyl nucleotidase CysQ: phosphate synthase methylvalerate L-ornithine leucyl/phenylalanyl- superpathway of purine deoxyribonucleosides degradation PSM7751_RS12045 AMP diphosphate PSM7751_RS05385 PSM7751_RS04545 pyrophosphohydrolase: dehydratase PSM7751_RS11385 phosphate xanthine dehydrogenase: β fatty acyl-CoA 6 PSM7751_RS13915 2-ene-1,7-dioic methylase: dehydrogenase: PSM7751_RS18180 RS02990 subunit HisF: 2,6-carboxylate N- hydro-lyase: L-homoserine reductase: CoA reductase: a [protein]- tRNA--protein N-acetyl-(N-acetyl- -D- E2 protein] N -S-[2- 6-methoxy-3-methyl-2- phosphodiesterase/ carrier-protein] UDP L-arabinopyranose acid aldolase: PSM7751_RS17575 a [lipoyl-carrierPSM7751_RS08705 PSM7751_RS19910 PSM7751_RS06450 succinyltransferase: large subunit: PSM7751_RS14755 PSM7751_RS04995 PSM7751_RS02470 PSM7751_RS18945 glucosaminyl)muramoyl- methylbutanoyl]dihydrolipoyl- all-trans-heptaprenyl- 5'-nucleotidase/ a 2-methoxy- dehydratase FabA: sulfite bifunctional ornithine L-cysteine transferase: 6 dAMP AMP PSM7751_RS20140 PSM7751_RS12430 homoserine O- ornithine isoleucine-- (3R)-3- a [protein] [+ 3 isozymes] L-alanyl-γ-D-glutamyl-L- L-lysine 1,4-benzoquinol PSM7751_RS09200 3'-nucleotidase: PSM7751_RS16475 protein]-N - O-phospho- imidazole glycerol (S)-3-methyl-2- acetyltransferase/ ile an N-terminal PSM7751_RS07185 succinate 6-(all-trans- a (2E)- acetyltransferase: carbamoyltransferase: O-phospho- tRNA ligase: hydroxybutanoyl- poly-[(R)-3- N-terminal L- 2'-deoxyguanosine lysyl-D-alanyl-D-alanine pyruvate PSM7751_RS01510 lipoyl-L-lysine L-homoserine phosphate synthase 2,3,4,5- oxopentanoate N-acetylglutamate acetylglutamate semialdehyde polyprenyl)phenol enoylpimeloyl- 2-isopropylmaleate PSM7751_RS19970 L-homoserine PSM7751_RS00420 hydroxybutanoate] arginyl-[protein] leucyl-L-arginine urate subunit HisH: tetrahydropyridine- PSM7751_RS09550 synthase: kinase: an L-isoleucyl- CoA 2'-deoxyadenosine 3'-AMP [acp] methyl ester RS09170 threonine synthase: branched-chain Ile a [protein] 3- PSM7751_RS06410 2,6-dicarboxylate N- O-acetyl-L- PSM7751_RS17610 PSM7751_RS20785 N-acetyl-L- [tRNA ] 3-isopropylmalate amino acid N-acetyl-L- threonine synthase: Ile PSM7751_RS07835 hydrogen sulfide Glu glutamate 5- a tRNA poly-beta- nitrosothio- succinyltransferase: dehydratase aminotransferase: homoserine PSM7751_RS07835 leucyl/phenylalanyl- purine-nucleoside L-citrulline glutamate semialdehyde hydroxybutyrate L-alanine D-erythro- PSM7751_RS15395 small subunit: acetylornithine tRNA--protein adenosine deaminase: phosphorylase: 2-methoxy-6-all 3-(all-trans thr AICAR PSM7751_RS17935 polymerase: a reduced adenine 1518 / 5'-deoxy-5'- cytidine a (3R,5Z)-3- (S)-1-pyrroline- imidazole-glycerol- N-succinyl- PSM7751_RS12425 transaminase: transferase: PSM7751_RS01675 PSM7751_RS08565 2-methylbutanoate trans-nonaprenyl- -decaprenyl) NaMN branched chain O-acetylhomoserine argininosuccinate thr PSM7751_RS12860 a [protein] electron-transfer UQ adenine 1519 in 16S rRNA fluoroadenosine 2',3'-cyclic hydroxydodec- 5-carboxylate RS15055 phosphate 2-amino-6- PSM7751_RS09545 PSM7751_RS07185 purine-nucleoside dGTP acetate--CoA ligase: purine-nucleoside benzene-1,2-diol bifunctional proline dIDP 3-isopropylmalate amino acid aminocarboxypropyltransferase: synthase: an N-terminal N-terminal L- flavoprotein electron transfer 1,4-benzoquinolbifunctional 16S rRNA monophosphate bifunctional 3- 5-enoyl-[acp]3-hydroxyacyl-[acyl- multifunctional 2',3'- threonine imidazoleglycerol- ketopimelate phosphorylase: deoxyguanosinetriphosphate 2',3'-cyclic-nucleotide nucleoside- dehydratase PSM7751_RS09430 PSM7751_RS17470 leu L-lysyl-[protein] purine-nucleoside PSM7751_RS16105 flavoprotein- demethylmenaquinone (adenine(1518)-N(6)/ phosphorylase: demethylubiquinol 3- carrier-protein] cyclic-nucleotide 2'- dehydrogenase/L- dehydratase: phosphate N-succinyldiaminopimelate aminotransferase: bifunctional ornithine poly-[(R)-3- a [protein]- leucyl-L-lysine triphosphohydrolase: 2'-phosphodiesterase: diphosphate kinase: large subunit: gln leucine--tRNA ligase: S-nitrosoglutathione 2'-deoxyinosine phosphorylase: PSM7751_RS15470 acetate--CoA ligase: adenine(1519)-N(6))- PSM7751_RS15470 phosphodiesterase/ glutamate gamma- PSM7751_RS17475 dehydratase: aminotransferase: PSM7751_RS08460 L-arginino- acetyltransferase/ L-tryptophan biosynthesis hydroxybutanoate] L-cysteine ubiquinone methyltransferase/2- PSM7751_RS12635 O-methyltransferase/ dehydratase FabZ: PSM7751_RS18230 an L-leucyl- PSM7751_RS08565 PSM7751_RS10255 dimethyltransferase: purine-nucleoside 5'-nucleotidase/ semialdehyde PSM7751_RS19060 PSM7751_RS15760 PSM7751_RS12430 succinate N-acetylglutamate PSM7751_RS07165 oxidoreductase: methoxy-6-polyprenyl-1,4- 2-polyprenyl-6- PSM7751_RS09885 RS02445 threonine PSM7751_RS06405 L-homocysteine [tRNA Leu ] S-(hydroxymethyl) deoxyguanosinetriphosphate PSM7751_RS19875 multifunctional 2',3'- dehydrogenase: nucleoside- N-succinyl- (2R,3S)-3- ile carbamoylsynthase: purine-nucleoside PSM7751_RS02515 benzoquinol methylase: 6 1518 phosphorylase: hydroxyphenol 3'-nucleotidase: ammonia-lyase: argininosuccinate Leu glutathione purine-nucleoside 2-methylbutanoyl- an oxidized N -dimethyladenine 3-hydroxyacyl-[acyl- imidazoleglycerol- N-acetyl-L- uracil degradation gln chorismate a tRNA triphosphohydrolase: AMP diphosphate PSM7751_RS08565 cyclic-nucleotide 2'- PSM7751_RS01510 PSM7751_RS14405 diphosphate kinase: L,L-2,6- isopropylmalate PSM7751_RS17610phosphate synthase NADH repair phosphorylase: CoA + PSM7751_RS13915 6 1519 methylase: PSM7751_RS16445 5-methyltetrahydropteroyltriglutamate- lyase: dehydrogenase/ phosphorylase: H UQH electron-transfer 6-methoxy-3-methyl-2- /N -dimethyladenine carrier-protein] β phosphate diaminopimelate ornithine I (reductive) PSM7751_RS15470 PSM7751_RS11550 2 5-fluoro-5- phosphodiesterase/ -D- PSM7751_RS04010 3-isopropylmalate methionine synthase: PSM7751_RS08760 large subunit: class III alcohol PSM7751_RS08565 flavoprotein all-trans-nonaprenyl- in 16S rRNA 6-(all-trans- PSM7751_RS17575 dehydratase FabA: Glu (2Z)-2-aminobut- dehydratase: succinyl- - homocysteine S-methyltransferase: 2'-deoxyguanosine PPP deoxy-D-ribose adenine 5'-nucleotidase/ ribosylnicotinate dITP dehydrogenase: PSM7751_RS04645 PSM7751_RS02315 uracil anthranilate synthase: i 1,4-benzoquinol PSM7751_RS16475 2-enoate PSM7751_RS06425 PSM7751_RS04640 dehydrogenase: NADH purine-nucleoside 1-phosphate 3'-nucleotidase: decaprenyl)-2- RS13700 diaminopimelate PSM7751_RS12390 [+ 2 isozymes] PSM7751_RS00545 a (2E,5Z)-dodeca- [+ 3 isozymes] arg carbamoyl PSM7751_RS21240 phosphorylase: PSM7751_RS01510 methoxy-phenol imidazole acetol- desuccinylase: 3,5-dienoyl-[acp] (2S)-2-isopropyl- L-asparagine phosphate synthase val PSM7751_RS15470 3'-cmp phosphate PSM7751_RS14895 anthranilate valine--tRNA ligase: S-(hydroxysulfenamide) 3-oxosuccinate biosynthesis III met small subunit: 5,6-dihydrouracil -glutathione histidinol-phosphate succinyl- PSM7751_RS07275 PSM7751_RS00275 an L-valyl- 2-iminobutanoate (tRNA-dependent) anthranilate 2-deoxy-α-D-ribose 1-phosphate diaminopimelate dihydropyrimidinase: [tRNA Val ] RS14825 transaminase: L-proline biosynthesis I carbamoyl phosphoribosyltransferase: 2-phospho-4-(cytidine 5'- 2-methoxy-6-all (indol-3- 5'-chloro-5'- a (3R)-3- a 3- a (3R,7Z)-3- desuccinylase: L-ornithine PSM7751_RS00520 a tRNA Val (R)-NADHX α-linolenate a (6S)-5- coenzyme A (R)-NADPHX NMN PSM7751_RS09795 asp phosphate PSM7751_RS04915 superpathway of pyrimidine deoxyribonucleosides degradation phosphopentomutase: diphospho)-2-C-methyl-D-erythritol Glu trans-hexaprenyl- yl)pyruvate deoxyadenosine hydroxyhexacosanoyl- demethyubiquinol hydroxy-hexadec- PSM7751_RS15420 4-methyl-2- bifunctional ADP- formyltetrahydrofolate dITP [+ 2 isozymes] [+ 2 isozymes] PSM7751_RS01680 bifunctional 2-C-methyl- long-chain fatty 1,4-benzoquinol indolepyruvate purine-nucleoside [acp] 3-hydroxyacyl-[acyl- bifunctional 3- 7-enoyl-[acp]3-hydroxyacyl-[acyl- bifunctional ADP- multifunctional 2',3'- oxopentanoate Glu N-(5-phosphoribosyl) hydroxylamine dependent NAD(P)H- bifunctional bifunctional L,L- 2'-deoxycytidine D-erythritol 4-phosphate acid--CoA ligase: ferredoxin phosphorylase: carrier-protein] demethylubiquinol 3- carrier-protein] dependent NAD(P)H- cyclic-nucleotide 2'- non-canonical L-histidinol- glutamate 5-kinase: superpathway of L-serine 3-ureidopropanoate -anthranilate hydrate dehydratase/ folylpolyglutamate demethylmenaquinone 2-oxobutanoate diaminopimelate branched-chain an L-aspartyl- 2-deoxy-D-ribose 5-phosphate cytidylyltransferase/2- PSM7751_RS14560 oxidoreductase: PSM7751_RS15470 dehydratase FabA: O-methyltransferase/ dehydratase FabZ: hydrate dehydratase/ phosphodiesterase/ purine NTP RS20595 phosphate Asn and glycine biosynthesis I N-(5'-phosphoribosyl) NAD(P)H-hydrate synthase/dihydrofolate methyltransferase/2- amino acid [tRNA ] PSM7751_RS19570 cytidine deaminase: C-methyl-D-erythritol [+ 6 isozymes] PSM7751_RS05010 2-polyprenyl-6- NAD(P)H-hydrate 5'-nucleotidase/ pyrophosphatase, diaminopimelate anthranilate ala epimerase: synthase: methoxy-6-polyprenyl-1,4- purine-nucleoside PSM7751_RS16475 PSM7751_RS09885 acetolactate synthase histidinol- aminotransferase: gamma- ornithine 2,4-cyclodiphosphate hydroxyphenol epimerase: 3'-nucleotidase: RdgB/HAM1 family: ala RS14380 ala epimerase: aspartyl/glutamyl- 3-phospho- alanine--tRNA ligase: PSM7751_RS05730 PSM7751_RS01690 deoxyribose- PSM7751_RS14775 benzoquinol methylase: [+ 2 isozymes] phosphorylase: large subunit: phosphatase: glutamyl kinase: carbamoyltransferase: isomerase: (S)-NADHX AMP diphosphate α-linolenoyl-CoA S-2-(indol-3 3-hydroxyacyl-[acyl- 3-hydroxyacyl-[acyl- PSM7751_RS17405 PSM7751_RS17935 tRNA(Asn/Gln) D-glycerate PSM7751_RS09995 an L-alanyl- ammonium thymidine synthase: a (6S)-5- PSM7751_RS13915 PSM7751_RS08565 methylase: PSM7751_RS05730 PSM7751_RS01510 PSM7751_RS16995 PSM7751_RS13620 phosphoglycerate PSM7751_RS15895 phosphate aldolase: 6-methoxy-3-methyl-2- carrier-protein] carrier-protein] 1-(β-D PSM7751_RS20090 γ PSM7751_RS10005 PSM7751_RS09550 Ala 2'-deoxyuridine PSM7751_RS03965 formyltetrahydrofolate yl)acetyl-CoA 5-chloro-5- PSM7751_RS17575 [+ 2 isozymes] branched chain amidotransferase -L-glutamyl dehydrogenase: β-alanine 1-(o- [tRNA ] PSM7751_RS18055 all-trans-hexaprenyl- dehydratase FabZ: dehydratase FabA: (S)-NADPHX ribofuranosyl) [+ 2 isozymes] histidinol meso- a tRNA Ala thymidine adenine deoxyribose dIMP amino acid subunit C: 5-phosphate PSM7751_RS18095 carboxyphenylamino) 2-C-methyl-D-erythritol- 1,4-benzoquinol PSM7751_RS09885 UQH PSM7751_RS16475 lys RS06830 lys diaminopimelate phosphorylase: CMP 2 a (2E,7Z)- nicotinamide (S)-2-aceto-2- phosphatase: aminotransferase: PSM7751_RS09695 2,4-cyclodiphosphate 1-phosphate a (2E)-hexacos- glutamate-5- 3-phosphoglycerate -1'-deoxyribulose PSM7751_RS01685 D-glyceraldehyde 3-phosphate hexadeca-2,7- hydroxybutanoate PSM7751_RS03165 diaminopimelate PSM7751_RS08460 acetaldehyde 2-enoyl-[acp] aspartyl/glutamyl- semialdehyde dehydrogenase: 5'-phosphate queuosine biosynthesis NADH uracil phosphorylase: dienoyl-[acp] ketol-acid decarboxylase: histidinol tRNA(Asn/Gln) dehydrogenase: PSM7751_RS03385 indole-3-glycerol PSM7751_RS01685 thymine ornithine ornithine PSM7751_RS08745 L-citrulline reductoisomerase: leu amidotransferase PSM7751_RS19565 3-phosphooxypyruvate phosphate synthase: arg arg asn preQ a 2-methoxy-6-all- PSM7751_RS07315 histidinol 0 a single 2-hydroxy-4-oxobutane- a (3R)-3- a (3R,5Z)-3- RS13105 subunit C: PSM7751_RS04925 isobutanoate a nucleoside adenosylcobinamide an L-cysteinyl- a nucleoside his his dehydrogenase: lys L-glutamate-5- phosphoserine argininosuccinate NADPH-dependent a ribonucleic acid trans-polyprenyl- hydroxytetracosanoyl- hydroxy-tetradec- (S)-NADPHX (R)-2,3-dihydroxy- PSM7751_RS18625 an L-asparaginyl- 2-deoxy-α- acetyl-CoA stranded DNA triphosphate 1,2,4-tricarboxylate [tRNA Cys ] diphosphate XTP lys lys semialdehyde (1S,2R)-1-C-(indol-3- 7-cyano-7- uracil acetate--CoA ligase: 1,4-benzoquinol bifunctional 3-methylpentanoate PSM7751_RS00885 aminotransferase: synthase: Asn Chemoautotrophic exodeoxyribonuclease DNA-directed bifunctional 4-carboxy-4-hydroxy- [acp] 3-hydroxyacyl-[acyl- aminoacyl-tRNA 5-enoyl-[acp]3-hydroxyacyl-[acyl- bifunctional ADP- nucleoside- an L-asparaginyl- yl)glycerol 3-phosphate [tRNA ] D-ribose 1- L-phenylalanine PSM7751_RS18090 PSM7751_RS17470 Asn deazaguanine Energy Metabolism VII small subunit: PSM7751_RS16105 2-oxoadipate adenosylcobinamide dependent NAD(P)H- diphosphate kinase: non-canonical 2,3-dihydroxy-3- histidinol Asn tRNA phosphate RNA polymerase demethylmenaquinone carrier-protein] hydrolase: carrier-protein] biosynthesis I [tRNA ] tryptophan synthase reductase QueF: PSM7751_RS17955 acetate--CoA ligase: aldolase/oxaloacetate kinase/ hydrate dehydratase/ PSM7751_RS04010 purine NTP methylvalerate dehydrogenase: 3-phospho- L-arginino- phosphopentomutase: subunit alpha: methyltransferase/2- dehydratase FabA: PSM7751_RS15865 dehydratase FabZ: RS12990 aminoacyl-tRNA subunit alpha: PSM7751_RS16495 hydrogen oxidation PSM7751_RS07165 decarboxylase: adenosylcobinamide- NAD(P)H-hydrate pyrophosphatase, hydro-lyase: PSM7751_RS13085 L-serine succinate PSM7751_RS01680 exodeoxyribonuclease PSM7751_RS20860 methoxy-6-polyprenyl-1,4- PSM7751_RS16475 aminoacyl-tRNA PSM7751_RS09885 nucleoside- chorismate hydrolase: (S)-1-pyrroline- PSM7751_RS15835 preQ I (aerobic) PSM7751_RS14095 phosphate epimerase: RdgB/HAM1 family: PSM7751_RS14755 argininosuccinate 1 purine ribonucleosides degradation VII large subunit: [+ 3 isozymes] benzoquinol methylase: hydrolase: diphosphate kinase: chorismate mutase: 5-carboxylate phosphoserine 2-deoxy-D-ribose isobutanoyl-CoA AMP diphosphate 3-hydroxyacyl-[acyl- 3-hydroxyacyl-[acyl- PSM7751_RS17405 histidinal PSM7751_RS15865 tryptophan synthase PSM7751_RS07590 PSM7751_RS13915 oxaloacetate pyruvate guanylyltransferase: PSM7751_RS05730 PSM7751_RS19060 (S)-3-methyl-2- lyase: aspartate-- tRNA guanosine(34) H a ribonucleic acid a 6-methoxy-3-methyl- carrier-protein] PSM7751_RS13715 carrier-protein] PSM7751_RS16685 pyrroline-5- phosphatase SerB: 2 5-phosphate a single-stranded a ribonucleoside PSM7751_RS08395 a nucleoside [+ 2 isozymes] aminoacyl-tRNA PSM7751_RS08760 subunit beta: asp Cys NADPH oxopentanoate histidinol tRNA ligase: transglycosylase Tgt: uptake hydrogenase 2-all-trans-polyprenyl- dehydratase FabZ: a tRNA cys dehydratase FabA: prephenate hydrolase: carboxylate reductase: PSM7751_RS18080 PSM7751_RS15885 adenosine oligodeoxyribonucleotide 5'-monophosphate adenosyl-cobinamide triphosphate XMP branched-chain dehydrogenase: PSM7751_RS02305 PSM7751_RS11225 small subunit: deoxyribose- 1,4-benzoquinol PSM7751_RS09885 a (2E,5Z)-PSM7751_RS16475 PSM7751_RS13715 PSM7751_RS09985 arg an L-aspartyl- phosphate a (2E)-tetracos- RS01900 ser asp a 7-aminomethyl-7- PSM7751_RS10380 amino acid PSM7751_RS00885 prephenate [+ 2 isozymes] ser indole [tRNA ] phosphate aldolase: tetradeca-2,5- S-adenosyl-L-methionine cycle II deazaguanosine 34 2-enoyl-[acp] aminotransferase: histidinol dehydratase: tRNA asp A(H2) PSM7751_RS18055 adenosine deaminase: dienoyl-[acp] asn in tRNA PSM7751_RS17935 dehydrogenase: PSM7751_RS12620 serine PSM7751_RS01675 pro tryptophan synthase tRNA preQ1(34) S- branched chain PSM7751_RS13085 keto- hydroxymethyltransferase: glyA met D-glyceraldehyde 6-methoxy-2-all- a 3,5,7,9,11,13,15- uridine 2'3'-cyclic a (3R,6Z)-3- a cis-delta21-39- a [protein]- methionine subunit beta: adenosylmethionine acetaldehyde (R)-4- isovalerate 3-(all-trans-heptaprenyl) a ribonucleoside amino acid phenylpyruvate 3-phosphate β-alanine a pimeloyl-[acp] ala trans-octaprenyl- hepta-oxo- monophosphate hydroxyoctadec- oxo-40-methyl- L-tyrosine adenosyltransferase: PSM7751_RS15885 ribosyltransferase- xanthosine adenosine inosine guanosine phosphopantoate benzene-1,2-diol diphosphate IDP RS11080 aminotransferase: his aromatic amino acid gly acetate--CoA ligase: 1,4-benzoquinone hexadecanoyl-[PKS-acp] bifunctional 3- 2',3'-cyclic-nucleotide 6-enoyl-[acp] C59:1-[acp] phosphate 5-methyltetrahydropteroyltriglutamate- PSM7751_RS16500 tyr isomerase QueA: bifunctional 8-amino-7- bifunctional aldo/keto reductase: ribonucleotide- 3-hydroxyacyl-[acyl- cyclopropane-fatty- protein tyrosine PSM7751_RS08460 aminotransferase: PSM7751_RS16105 demethylubiquinol 3- 2'-phosphodiesterase: nucleoside- L-cysteine biosynthesis I - homocysteine S-methyltransferase: tyrosine--tRNA ligase: PSM7751_RS05140 phosphopantothenoylcysteine oxononanoate demethylmenaquinone PSM7751_RS00185 diphosphate carrier-protein] acyl-phospholipid phosphatase: PSM7751_RS15075 trp PSM7751_RS03825 acetate--CoA ligase: O-methyltransferase/ PSM7751_RS12635 diphosphate kinase: L-glutamate L-glutamate an L-tyrosyl- 34 purine-nucleoside purine-nucleoside purine-nucleoside decarboxylase/ synthase: methyltransferase/2- aldo/keto reductase: reductase dehydratase FabA: synthase: ile PSM7751_RS04640 an epoxyqueuosine purine-nucleoside PSM7751_RS07615 PSM7751_RS19060 Tyr acetyl-CoA PSM7751_RS07165 2-polyprenyl-6- multifunctional 2',3'- subunit alpha: PSM7751_RS16475 biosynthesis II biosynthesis III [+ 3 isozymes] [tRNA ] in tRNA phosphorylase: phosphorylase: phosphorylase: phosphorylase: phosphopantothenate PSM7751_RS01175 methoxy-6-polyprenyl-1,4- 9-hydroxy-3,5,7,11,13,15-PSM7751_RS08570 PSM7751_RS15340 phosphotyrosine phe ser a tRNA Tyr 8-amino-7- hydroxyphenol cyclic-nucleotide 2'- nucleoside- epoxyqueuosine PSM7751_RS15470 PSM7751_RS08565 PSM7751_RS08565 PSM7751_RS08565 synthase: PSM7751_RS08385 acyl-carrier protein benzoquinol methylase: hexaoxohexadecanoyl- PSM7751_RS04525 3-hydroxyacyl-[acyl- [+ 2 isozymes] protein phosphatase: RS16755 L-glutamine serine O- (R)-4'- isovaleryl-CoA AMP diphosphate oxononanoate methylase: phosphodiesterase/ a cis-keto-C60- diphosphate kinase: L-ornithine 2-oxoglutarate 2-oxoglutarate L-alanine reductase: purine-nucleoside purine-nucleoside purine-nucleoside purine-nucleoside 3-methyl-6-methoxy-PSM7751_RS13915 [PKS-acp] a 2'- [+ 3 isozymes] carrier-protein] PSM7751_RS09520 biosynthesis I acetyltransferase: glutamate glutamate L-homocysteine SAM phosphopantothenate PSM7751_RS17575 5'-nucleotidase/ meroacyl-[acp] PSM7751_RS04010 degradation I (L- biosynthesis III PSM7751_RS17840 phosphorylase: phosphorylase: phosphorylase: phosphorylase: 2-octaprenyl-1,4- deoxyribonucleoside dehydratase FabZ: a [protein]- PSM7751_RS05300 dehydrogenase: dehydrogenase: 2-methoxy-6-(all-trans 3'-nucleotidase: L-tyrosine ITP proline biosynthesis) 34 benzoquinone 5'-diphosphate PSM7751_RS09885 O-acetyl-L-serine PSM7751_RS00665 a queuosine UTP and CTP dephosphorylation I PSM7751_RS08565 PSM7751_RS15470 PSM7751_RS15470 PSM7751_RS15470 -heptaprenyl)phenol a (2E,6Z)- RS20340 Glu PSM7751_RS00665 tryptophan-- PSM7751_RS01510 L-ornithine cys a tRNA Trp in tRNA octadecadienoyl- glutamine synthetase: Glu Glu tRNA ligase: UTP α-D-ribose- 3'-UMP ornithine cysteine synthase A: cysteine desulfurase: [acp] RS08525 PSM7751_RS00360 PSM7751_RS08455 an L-tryptophanyl- 1-phosphate cyclodeaminase: PSM7751_RS04120 PSM7751_RS19410 [+ 3 isozymes] Trp CTP synthetase: adenosylhomocysteinase: [tRNA ] thymine degradation PSM7751_RS14795 phosphopentomutase: (R)-4'- 3-(all-trans- a (3R,9Z)-3- 527 gln ala PSM7751_RS14390 trp PSM7751_RS00305 2-(2-carboxy-4- D-ribulose a [protein]-L- a guanine pro cys lipoprotein posttranslational PSM7751_RS01680 phosphopantothenoyl- phytenate [DNA] 3-demethylubiquinol-6 nonaprenyl) methylthiazol-5- HMP-PP 5-phosphate β-isoaspartate hydroxy-octadec- in 16S rRNA asp ITP RS00790 SAH modification UMP thymine L-cysteine long-chain fatty 3,4-dihydroxy- benzene-1,2-diol protein-L-isoaspartate CTP D-ribose 5- bifunctional exodeoxyribonuclease yl)ethyl phosphate thiamine phosphate bifunctional 3- bifunctional 3- 9-enoyl-[acp]3-hydroxyacyl-[acyl- 16S rRNA aspartate acid--CoA ligase: 2-butanone-4- O-methyltransferase: non-canonical a [prolipoprotein]- multifunctional 2',3'- phosphate phosphopantothenoylcysteine III: PSM7751_RS15800 synthase: demethylubiquinol 3- demethylubiquinol 3- carrier-protein] (guanine(527)-N(7) aminotransferase: RS11575 PSM7751_RS14560 phosphate synthase: PSM7751_RS11540 purine NTP L-cysteine cyclic-nucleotide 2'- 5,6-dihydrothymine decarboxylase/ exodeoxyribonuclease PSM7751_RS19540 O-methyltransferase/ O-methyltransferase/ dehydratase FabZ: )-methyltransferase PSM7751_RS15760 threonine-- phosphodiesterase/ adenosine [+ 6 isozymes] III: PSM7751_RS10280 PSM7751_RS00060 2-polyprenyl-6- protein-L-isoaspartate RsmG: pyrophosphatase, thr prolipoprotein phosphopantothenate a 2'- thiamine-phosphate 1-deoxy-L- 2-polyprenyl-6- PSM7751_RS09885 aspartate tRNA ligase: CMP dihydropyrimidinase: nucleotides hydroxyphenol O-methyltransferase: PSM7751_RS17380 RdgB/HAM1 family: diacylglyceryl 5'-nucleotidase/ synthase: PSM7751_RS08385 hydroxyphenol an N 7 - Nucleoside and Nucleotide Biosynthesis PSM7751_RS08145 PSM7751_RS00520 diphosphate AMP phytenoyl-CoA deoxyribonucleoside [DNA] diphosphorylase: glycero-tetrulose formate 3-hydroxyacyl-[acyl- aminotransferase: PSM7751_RS17405 RS18545 an L-threonyl- 3'-nucleotidase: degradation III methylase: PSM7751_RS07665 527 transferase: multifunctional 2',3'- pseudouridine 4'-phosphopantetheine 5'-monophosphate PSM7751_RS06115 4-phosphate methylase: a protein L-β- carrier-protein] methylguanine [tRNA Thr ] [+ 2 isozymes] PSM7751_RS17575 PSM7751_RS08285 [+ 2 isozymes] PSM7751_RS09350 PSM7751_RS01510 degradation thiamine PSM7751_RS17575 in 16S rRNA a tRNA Thr cyclic-nucleotide 2'- 2-methoxy- isoaspartate dehydratase FabA: oxaloacetate RS18665 superpathway of pyrimidine a [prolipoprotein]- 3-(carbamoylamino)- AMP phosphate ubiquinol-6 α IMP UMP biosynthesis III superpathway of adenosine pyrimidine deoxyribonucleotides adenine and superpathway of 5-aminoimidazole superpathway of pyrimidine uridine phosphodiesterase/ 6-(all-trans- -methyl ester a (2E,9Z)-PSM7751_RS16475 ribonucleotides de novo biosynthesis (S-diacylglyceryl) 2-methylpropanoate pseudouridine nucleotides de novo biosynthesis I de novo biosynthesis III adenosine salvage III ribonucleotide biosynthesis nucleobases salvage 5'-nucleotidase/ AMP nucleosidase: nonaprenyl)phenol octadeca-2,9- -L-cysteine 3'-nucleotidase: UDP CTP PSM7751_RS17980 dienoyl-[acp] RS17740 gln hydrogencarbonate hydrogencarbonate gln PRPP uracil PSM7751_RS01510 ribonucleotide- signal peptidase II: pseudouridine adenine IMP asp adenine uracil diphosphate amidophosphoribosyltransferase: ser cytidine purine-nucleoside phosphoribosyltransferase: serine--tRNA ligase: PSM7751_RS15585 (R)-3-amino-2- 5'-phosphate DNA combined with exogenous DNA α,ω-9Z- a pseudouridine 1915 a guanine 966 a supercoiled RS15755 carbamoyl carbamoyl CDP PSM7751_RS11515 α sn-glycerol 3-demethylubiquinol-9 a ribonucleoside a ribonucleoside reductase phosphorylase: PSM7751_RS01670 PSM7751_RS05870 methylpropanoate Degradation/Utilization/Assimilation - Other to form a recombinational junction octadecenedioate ADP- -D-glucose in 23S rRNA a tRNA precursor in 16S rRNA duplex DNA 3'-AMP phosphate synthase phosphate synthase amidophosphoribosyltransferase: an L-seryl- an (S-diacyl- pseudouridine- 3-phosphate dGDP 5'-monophosphate 3'-phosphate adenylosuccinate subunit alpha: UMP ser a lipoprotein Holliday junction resolvase long-chain fatty 23S rRNA bifunctional 3- 16S rRNA ATP-dependent large subunit: large subunit: ribonucleotide- PSM7751_RS08565 [tRNA ] glucosylglycerol- ribonuclease D: multifunctional 2',3'- multifunctional 2',3'- multifunctional 2',3'- synthase: PSM7751_RS02820 β PSM7751_RS17550 ser sn-glyceryl) 5-phosphate RuvX: PSM7751_RS05975 acid--CoA ligase: ribonucleotide-diphosphate diphosphate purine-nucleoside 5-phospho- - a tRNA signal peptide octane oxidation phosphate synthase: (pseudouridine(1915)- PSM7751_RS10680 demethylubiquinol 3- cyclic-nucleotide 2'- cyclic-nucleotide 2'- (guanine(966)-N(2) DNA helicase RecG: cyclic-nucleotide 2'- RS12050 PSM7751_RS02315 PSM7751_RS02315 PSM7751_RS00290 cytidylate kinase: -L-cysteinyl- glycosidase: acrylonitrile reductase subunit alpha: [+ 3 isozymes] reductase phosphorylase: D-ribosylamine crossover junction PSM7751_RS14560 PSM7751_RS13610 N(3))-methyltransferase O-methyltransferase/ phosphodiesterase/ )-methyltransferase PSM7751_RS20040 phosphodiesterase/ carbamoyl carbamoyl PSM7751_RS15950 [apolipoprotein] PSM7751_RS12935 degradation I 2-O-(α-D- ribonuclease D: PSM7751_RS04525 phosphodiesterase/ dUDP subunit alpha: phosphoribosylamine- endodeoxyribonuclease [+ 6 isozymes] RlmH: 2-polyprenyl-6- RsmD: replicative 5'-nucleotidase/ phosphate synthase phosphate synthase adenylo-succinate PSM7751_RS15470 UMP kinase: NADH glucopyranosyl) PSM7751_RS17725 5'-nucleotidase/ 5'-nucleotidase/ RS07085 PSM7751_RS02820 uracil RuvC: PSM7751_RS08085 ω-carboxy- ADP PSM7751_RS12445 hydroxyphenol ribonucleotide-diphosphate PSM7751_RS14700 nucleoside- adenosine -glycine ligase: an N 3 - a nucleoside 5'- 3'-nucleotidase: 3'-nucleotidase: an N 2 - DNA helicase: 3'-nucleotidase: small subunit: small subunit: PSM7751_RS09925 acrylonitrile resolution of recombinational junction AMP diphosphate (9Z)-octadec- -sn-glycerol a tRNA 1915 monophosphate methylase: reductase subunit alpha: 966 PSM7751_RS11400 adenylosuccinate diphosphate kinase: [+ 3 isozymes] PSM7751_RS02060 a peptide 3-phosphate methylpseudouridine PSM7751_RS01510 PSM7751_RS01510 methylguanine PSM7751_RS01510 PSM7751_RS07275 PSM7751_RS07275 UDP pro an N-acyl-(S- formation of two intact strands 9-enoyl-CoA PSM7751_RS17575 PSM7751_RS02820 a single lyase: PSM7751_RS19060 dCDP adenosine deaminase: proline--tRNA ligase: a reduced in 23S rRNA a ribonucleoside a ribonucleoside in 16S rRNA carbamoyl carbamoyl superpathway of guanosine GAR diacyl-sn-glyceryl) n-octane GDP stranded DNA adenosine RS08325 asp asp PSM7751_RS05770 nucleoside- PSM7751_RS01675 nucleoside-diphosphate PSM7751_RS16655 an L-prolyl- rubredoxin ubiquinol-9 phosphate phosphate nucleotides de novo biosynthesis I nucleoside- -L-cysteinyl- acrylamide diphosphate kinase: phosphoribosylglycinamide kinase: PSM7751_RS19060 [tRNA Pro ] diphosphate kinase: [lipoprotein] alkane 1- RS00415 AMP PSM7751_RS04010 formyltransferase: nucleoside-diphosphate a tRNA Pro Inorganic Nutrient Metabolism amidase: PSM7751_RS19060 monooxygenase: aspartate aspartate IMP inosine PSM7751_RS10690 kinase: PSM7751_RS04010 PSM7751_RS15765 dUTP methylmalonate a 2-methyl a (7Z,10Z,13Z,16Z 4-(cytidine 5'- 4-hydroxy- succinate carbamoyltransferase: carbamoyltransferase: nucleoside- PSM7751_RS10335 a (7Z)-hexadec- 3-demethylubiquinol-7 propan-1-ol NAD + NADPH adenylate kinase: UTP aminomethylphosphonate degradation [+ 3 isozymes] branched 2,3,4- a malonyl-[acp] ,19Z)-3-oxodocosa- diphospho)-2-C- 4-methyl-2- semialdehyde 3'-GMP PSM7751_RS02610 PSM7751_RS02610 deoxyuridine diphosphate kinase: purine-nucleoside FGAR glyphosate degradation III superpathway of sulfate assimilation semialdehyde 7-enoyl-[acp] dADP RS16395 PSM7751_RS20875 IMP dehydrogenase: 1-octanol methylmalonate- saturated fatty acid 7,10,13,16,19-pentaenoyl-[acp] methyl-D-erythritol bifunctional 3- NAD(P)-dependent NAD(P)(+) oxoglutarate NAD-dependent PSM7751_RS04010 phosphorylase: CTP synthetase: 5-oxo-L-proline metabolism and cysteine biosynthesis acrylate acyl-CoA synthetase: beta-ketoacyl-[acyl- 3-oxoacyl-ACP 4-(cytidine 5'- 4-carboxy-4-hydroxy- multifunctional 2',3'- PSM7751_RS10035 5'-triphosphate phenylalanine--tRNA demethylubiquinol 3- ribonucleotide-diphosphate alcohol dehydrogenase: transhydrogenase: adenylate kinase: phosphoribosylformylglycinamidine PSM7751_RS00305 aminomethylphosphonate semialdehyde PSM7751_RS02115 carrier-protein] reductase: diphospho)-2-C-methyl- 2-oxoadipate succinate- cyclic-nucleotide 2'- N-carbamoyl- N-carbamoyl- IMP dehydrogenase: nucleotidohydrolase: dCTP PSM7751_RS08565 ligase subunit beta: an N-terminal reductase subunit alpha: PSM7751_RS13945 PSM7751_RS06675 RS12850 PSM7751_RS16110 synthase II: PSM7751_RS05020 glyphosate sulfate dehydrogenase [+ 6 isozymes] synthase I: PSM7751_RS09075 D-erythritol kinase: O-methyltransferase/ aldolase/oxaloacetate semialdehyde phosphodiesterase/ L-aspartate L-aspartate PSM7751_RS08780 PSM7751_RS08380 purine-nucleoside CTP PSM7751_RS12745 L-glutaminyl- an N-terminal L- a 2-methyl PSM7751_RS04525 [+ 2 isozymes] adenine salvage phosphonate C- 3-phospho- (CoA acylating): PSM7751_RS16480 [+ 6 isozymes] 2-phospho-4-(cytidinePSM7751_RS02525 2-polyprenyl-6- NAD(P)-dependent NAD(P) decarboxylase: dehydrogenase: 5'-nucleotidase/ [+ 2 isozymes] phosphorylase: [protein] glutamyl-[protein] branched a (9Z)-3-oxo- a (3R,7Z,10Z,13Z,16Z dihydroorotase: dihydroorotase: ADP phenylalanine--tRNA P lyase system sulfate D-glycerate PSM7751_RS05085 AMP diphosphate hydroxyphenol ribonucleotide-diphosphate alcohol dehydrogenase: transhydrogenase PSM7751_RS16195 3'-nucleotidase: PSM7751_RS15470 phe 2-N-acetamidomethylphosphonate 1-octanal 2,3,4-saturated acyl-carrier protein octadec-9- ,19Z)-3-hydroxydocosa- 5'-diphospho)-2-C- PSM7751_RS14095 XMP FGAM ligase subunit alpha: protein PhnL: + methylase: reductase subunit alpha: RS06850 PSM7751_RS11390 PSM7751_RS11390 dUMP adenylyltransferase phosphoglycerate H NADH hydrogencarbonate propanoyl-CoA enoyl-[acp] 7,10,13,16,19-pentaenoyl-[acp] methyl-D-erythritol PSM7751_RS04545 subunit beta: pntB pyruvate [+ 2 isozymes] PSM7751_RS01510 fatty acyl-CoA PSM7751_RS02820 adenine PSM7751_RS12765 an L-phenylalanyl- PSM7751_RS06320 small subunit: dehydrogenase: PSM7751_RS17575 1-propanal NADP + NADH succinate dihydroorotase: dihydroorotase: thymidylate inosine-5'-phosphate biosynthesis I hypoxanthine phosphoribosylformylglycinamidine phosphonate C-P lyase 4-trimethylaminobutyraldehyde Phe guanosine PSM7751_RS02620 PSM7751_RS02620 ATP synthase F1 ribonucleotide- [tRNA ] system protein PhnL: α-D-ribose-1-[[+N 2- isozymes] PSM7751_RS20640 PSM7751_RS18095 dehydrogenase: ubiquinol-7 ADP RS11725 synthase (FAD): cyclo-ligase: PSM7751_RS10695 Phe a [protein] with subunit epsilon: a tRNA γ (phosphonomethyl) diphosphate PSM7751_RS08215 hypoxanthine an N-terminal 5- -L-glutamyl PSM7751_RS06320 APS 3-phosphoglycerate PSM7751_RS16195 (S)-dihydroorotate (S)-dihydroorotate PSM7751_RS09715 AIR glutathione glycine]-5- reductase phosphoribosyltransferase: AIR adenine adenine deaminase: oxo-L-proline 5-phosphate Respiration [+ 2 isozymes] dehydrogenase: dTMP α octanoate [+ 7 isozymes] subunit alpha: PSM7751_RS03945 phosphoribosyltransferase: PSM7751_RS15130 -D-ribose-1-(2-N- triphosphate adenylyl- PSM7751_RS03385 a 3-methyl- an [amino group carrier protein]- RS00350 dihydroorotate dihydroorotate GMP 5-(carboxyamino)imidazole alpha-D-ribose 1- a (2R)-2-hydroxy a nucleoside 3-demethylubiquinol- PSM7751_RS02820 dTMP kinase: PSM7751_RS07790 acetamidomethylphosphonate) sulfate kinase: acyl-CoA synthetase: branched 2,3,4- a (3Z)-dec- a malonyl-[acp] C-terminal-γ-(L-glutamate 5- butan-1-ol phytol D-glycerate acetyl-CoA dehydrogenase dehydrogenase ribonucleotide synthase: xanthine 2-oxoglutarate decarboxylation to succinyl-CoA methylphosphonate 3-phosphooxypyruvate even numbered ATP H O triphosphate 10 IMP [+ 3 isozymes] PSM7751_RS09255 methionine-- -5-triphosphate PSM7751_RS20645 saturated fatty acid 3-enoyl-[acp] semialdehyde-2-yl)-L-glutamate 2 NAD(P)-dependent NAD(P)-dependent RS14110 (quinone): electron PSM7751_RS09390 phosphoribosyltransferase: met 5-triphosphate PSM7751_RS02115 straight chain 2,3,4- acyl-CoA synthetase: beta-ketoacyl-[acyl- N-acetyl-gamma- nucleoside triphosphate bifunctional 3- glyoxylate/ acetyl-CoA ATP guanylate kinase: hypoxanthine tRNA ligase: a [2-oxoglutarate alpha-D-ribose 1- acyl-CoA synthetase: ATPase: alcohol dehydrogenase: alcohol dehydrogenase: multifunctional 2',3'- PSM7751_RS01565 transfer subunit: dTDP PSM7751_RS04880 phosphoserine [+ 6 isozymes] saturated fatty acid PSM7751_RS02115 carrier-protein] glutamyl-phosphate pyrophosphohydrolase: demethylubiquinol 3- hydroxypyruvate carboxylase, N5-CAIR PSM7751_RS00200 an L-methionyl- 5-oxo-L-proline dehydrogenase methylphosphonate diphosphatase: PAPS PSM7751_RS20825 cyclic-nucleotide 2'- PSM7751_RS04240 AMP aminotransferase: PSM7751_RS02115 reductase: PSM7751_RS19910 O-methyltransferase/ PSM7751_RS13945 PSM7751_RS13945 reductase A: carboxyltransferase PRPP PSM7751_RS03215 nucleoside- [elongator 6 5-triphosphate PSM7751_RS09400 octanoyl-CoA a (R)-2-hydroxy even [+ 6 isozymes]a 3-methyl- synthase I: orotate dADP hypoxanthine E2 protein] N 2-oxoglutarate PSM7751_RS18090 [+ 6 isozymes] [+ 8 isozymes] 2-polyprenyl-6- PSM7751_RS09095 subunit beta: phosphodiesterase/ RS09815 PRPP diphosphate kinase: 5-(carboxyamino)imidazole IMP elongator tRNA Met ] α-D-ribose-1-[N- phosphoadenosine PSM7751_RS16480 an [amino group carrierPSM7751_RS04995 protein]- NTP NAD(P)-dependent NAD(P)-dependent 5-oxoprolinase: -lipoyl-L-lysine diphosphatase: numbered straight branched a (5Z)-3- + 5'-nucleotidase/ orotate phosphoribosyltransferase: Met dehydrogenase AMP diphosphate H phosphate ADP hydroxyphenol PSM7751_RS14770 GDP PSM7751_RS19060 ribonucleotide mutase: tRNA (phosphonomethyl) phosphosulfate diphosphate AMP C-terminal-γ-(5-phospho- pyrophosphohydrolase: alcohol dehydrogenase: alcohol dehydrogenase: [+ 4 isozymes] orotate PSM7751_RS03945 PSM7751_RS01990 2-oxoglutarate PSM7751_RS09400 3-phospho- chain 2,3,4-saturated 2,3,4-saturated acyl-carrier protein oxododec- 3'-nucleotidase: nucleoside- PSM7751_RS09395 E1 component: α-D-ribose-1-(2-N- glycine] 5-phosphate reductase: L-glutamyl)-L-glutamate PSM7751_RS17605 methylase: PSM7751_RS04545 PSM7751_RS04545 hydroxypyruvate [+ 3 isozymes] RS12100 phosphoribosyltransferase: nucleoside- dehydrogenase L-serine fatty acyl CoA fatty acyl-CoA 5-enoyl-[acp] PSM7751_RS01510 orotate diphosphate kinase: xanthine PSM7751_RS08680 acetamidomethylphosphonate) α-D-ribose-1-[N- PSM7751_RS11310 a nucleoside 5'- PSM7751_RS17575 butan-1-al phytenal malonyl-CoA PSM7751_RS11395 phosphoribosyltransferase: diphosphate kinase: asp Glu E1 component: phosphoserine PSM7751_RS19060 CAIR xanthine and phosphoribosyltransferase: 5-phosphate (phosphonomethyl) monophosphate ubiquinol-10 inosine nucleoside- ribonucleotide- PSM7751_RS04010 superpathway of pyrimidine deoxyribonucleoside salvage PSM7751_RS08680 phosphoadenosine orotate PSM7751_RS11395 nucleoside- xanthosine salvage PSM7751_RS04880 carbon- glycine]-5-phosphate phosphatase SerB: diphosphate kinase: diphosphate a tRNA Lys phosphosulfate RS20880 phosphoribosyltransferase: orotate diphosphate kinase: dTTP lysine--tRNA ligase: [+ 2 isozymes] a [2-oxoglutarate a [2-oxoglutarate phosphorus lyase: C-P-lyase: PSM7751_RS18080 PSM7751_RS19060 reductase phosphoribosylaminoimidazolesuccinocarboxamide 2'-deoxycytidine reductase: thr RS16910 thr PSM7751_RS03230 phosphoribosyltransferase: PSM7751_RS04010 synthase: PSM7751_RS10630 IMP PSM7751_RS16335 an L-lysyl- dehydrogenase dehydrogenase PSM7751_RS06330 PSM7751_RS06330 PSM7751_RS11385 nucleoside- subunit alpha: 6 6 α ser an odd numbered 2030 PSM7751_RS03230 xanthosine Lys E2 protein] N E2 protein] N -S- 5-phospho- - adenine 6 37 a glutaryl-[acp] a (5Z)-tetradec- benzyl alcohol ethanol butan-1-ol D-glycerate (S)-NADHX histidinol diphosphate kinase: PSM7751_RS02820 cytidine deaminase: [tRNA ] N -L-threonylcarbamoyladenosine carbon-phosphorus straight chain a malonyl-[acp] a malonyl-[acp] pimeloyl-CoA ala thr orotidine 5'- dATP purine-nucleoside -dihydrolipoyl- succinyldihydrolipoyl- D-ribose 1,2- sulfite in 23S rRNA PSM7751_RS01690 lys -modified tRNA biosynthesis lyase complex serine O- 2,3,4-saturated methyl ester 5-enoyl-[acp] NAD(P)-dependent NAD(P)-dependent NAD(P)-dependent 23S rRNA glyoxylate/ histidinol PSM7751_RS04010 [+ 3 isozymes] SAICAR L-lysine L-lysine cyclic phosphate beta-ketoacyl-[acyl- beta-ketoacyl-[acyl- 8-amino-7- bifunctional ADP- phosphate orotidine 5'- phosphorylase: subunit PhnI: acetyltransferase: acyl-CoA synthetase: threonine dehydratase: alcohol dehydrogenase: alcohol dehydrogenase: alcohol dehydrogenase: dehydrogenase: thr RS18975 thr dCMP fatty acid carrier-protein] carrier-protein] oxononanoate (adenine(2030)-N(6) hydroxypyruvate dependent NAD(P)H- RS16505 phosphate 2'-deoxyuridine PSM7751_RS15470 PSM7751_RS06335 PSM7751_RS02115 PSM7751_RS17475 orotidine-5'-phosphate adenylosuccinate lyase: thr PSM7751_RS05300 synthase I: PSM7751_RS13945 PSM7751_RS13945 PSM7751_RS13945 )-methyltransferase reductase A: hydrate dehydratase/ PSM7751_RS13085 guanine and cytidylate kinase: purine-nucleoside an odd numbered synthase I: synthase: threonine ammonia-lyase: decarboxylase: PSM7751_RS05770 5-phospho-α-D-ribose [+ 6 isozymes] NAD(P)-dependent NAD(P)-dependent NAD(P)-dependent RlmJ: PSM7751_RS06725 NAD(P)H-hydrate histidinol orotidine-5'-phosphate GTP dGDP guanosine salvage PSM7751_RS15950 threonylcarbamoyl- straight chain PSM7751_RS16480 PSM7751_RS16480a (7Z)-3-oxo- PSM7751_RS01175 thymidine kinase: phosphorylase: 2-oxoglutarate α-D-ribose 1,5- O-acetyl-L-serine diphosphate AMP 8-amino-7- PSM7751_RS16445 PSM7751_RS15985 PSM7751_RS14485 decarboxylase: his AMP synthase: 1,2-cyclic phosphate hydrogen sulfide a 3-oxopimeloyl- alcohol dehydrogenase: alcohol dehydrogenase: alcohol dehydrogenase: 6 [+ 4 isozymes] epimerase: dehydrogenase: AICAR PSM7751_RS02325 dCDP PSM7751_RS08565 dehydrogenase 2,3,4-saturated acyl-carrier protein acyl-carrier protein hexadec-7- coenzyme A 2-oxobutanoate an N - PSM7751_RS14485 histidine--tRNA ligase: bisphosphate [acp] methyl ester oxononanoate PSM7751_RS04545 PSM7751_RS04545 PSM7751_RS04545 2030 PSM7751_RS05730 PSM7751_RS00885 RS13765 UMP nucleoside- xanthine PSM7751_RS02575 E1 component: fatty acyl CoA enoyl-[acp] methyladenine hydroxypyruvate thymidine PSM7751_RS02235 an L-histidyl- L-threonylcarbamoyladenylate methylphosphonate benzaldehyde acetaldehyde butan-1-al NADH predicted UMP adenine and diphosphate kinase: guanosine bifunctional dUMP nucleoside- PSM7751_RS08680 cysteine synthase A: in 23S rRNA his cytidylate kinase: xanthine [tRNA His ] degradation I ABC PSM7751_RS19060 purine-nucleoside diphosphate kinase: 6 adenosine salvage I phosphoribosylaminoimidazolecarboxamide His N -L- PSM7751_RS04120 urea urea PSM7751_RS15950 thymidine kinase: phosphoribosyltransferase: a tRNA dihydrolipoamide transporter adenine and nucleoside- phosphorylase: formyltransferase/IMP PSM7751_RS19060 threonylcarbamoyladenine α-D-ribose 1,5-bisphosphate UMP kinase: PSM7751_RS02325 PSM7751_RS04880 succinyltransferase: methylphosphonate of urea adenosine salvage VI diphosphate kinase: PSM7751_RS08565 cyclohydrolase: PSM7751_RS15590 nucleoside- synthase: PSM7751_RS14350 PRPP PSM7751_RS08685 phosphonate C- an N 6 -L- (R)-4-hydroxy- a 1-acyl-sn PSM7751_RS09925 adenosine PSM7751_RS04010 purine-nucleoside diphosphate kinase: 6 cys an N -L- 37 a sulfurated a malonyl-[acp] a (3Z)-dodec- 5'-deoxyadenosine DMKH2-11 MeOH DMKH D-glycerate RS05850 CMP phosphorylation adenine P lyase system threonylcarbamoyladenine a malonyl-[acp] a malonyl-[acp] 3'-dephospho- 2 4-methyl-2- met -glycerol 3- ectoine RS09105 ectoine UDP purine-nucleoside phosphorylase: FAICAR PSM7751_RS04010 XMP threonylcarbamoyladenine 37 [sulfur carrier] methyl ester 3-enoyl-[acp] ATP glycine--tRNA phosphoribosyltransferase: protein PhnL: in tRNA beta-ketoacyl-[acyl- methylthioadenosine CoA bifunctional NAD(P)-dependent bifunctional oxoglutarate glyoxylate/ bifunctional ornithine phosphate phosphorylase: adenosine dGTP PSM7751_RS15470 dTMP in tRNA tRNA (N(6)-L- beta-ketoacyl-[acyl- dephospho- 4-carboxy-4-hydroxy- nucleoside- CMP bifunctional dCTP ligase subunit beta: PSM7751_RS07790 PSM7751_RS06320 phosphorylase: demethylmenaquinone alcohol dehydrogenase: demethylmenaquinone hydroxypyruvate PSM7751_RS08565 guanine PRPP threonylcarbamoyladenosine(37) carrier-protein] carrier-protein] CoA kinase: 2-oxoadipate acetyltransferase/ cytidylate kinase: adenosine kinase: 2-oxoisovalerate decarboxylation to isobutanoyl-CoA [+ 2 isozymes] PSM7751_RS07795 methyltransferase/2- PSM7751_RS13945 reductase A: diphosphate kinase: purine-nucleoside phosphoribosylaminoimidazolecarboxamide dTMP kinase: PSM7751_RS07445 α-D-ribose-1- -C(2))- methylthiotransferase synthase I: synthase I: methyltransferase/2- aldolase/oxaloacetate N-acetylglutamate PSM7751_RS15950 PSM7751_RS18160 diphosphate PSM7751_RS17345 PSM7751_RS09095 selenate RS05545 selenate PSM7751_RS19060 formyltransferase/IMP PSM7751_RS09255 glycine--tRNA adenine methylphosphonate- MtaB: PSM7751_RS13625 6 PSM7751_RS16480 PSM7751_RS16480 5-deoxy-α-ribose methoxy-6-polyprenyl-1,4- NAD(P)-dependent methoxy-6-polyprenyl-1,4- synthase: a 1-acyl-2- CDP phosphorylase: hypoxanthine an [apo BCAA selenate reduction a 2-methylsulfanyl-N -L- a (5Z)-3-oxo- + decarboxylase: cyclohydrolase: PSM7751_RS15590 gly phosphoribosyltransferase: an unsulfurated a 3-oxoglutaryl- adenine ADP coenzyme A H benzoquinol methylase: alcohol dehydrogenase: benzoquinol methylase: [+ 4 isozymes] RS01295 nucleoside- PSM7751_RS15470 AMP phosphoribosyltransferase: dTDP ligase subunit alpha: dehydrogenase 5-triphosphate met 5'-deoxyadenosine threonylcarbamoyladenine 37 acyl-carrier protein acyl-carrier protein tetradec-5- 1-phosphate PSM7751_RS14095 PSM7751_RS17610 palmitoyl-sn nucleoside- manganese- diphosphate kinase: 6 PSM7751_RS07790 alpha-D-ribose 1- [sulfur carrier] [acp] methyl ester PSM7751_RS13915 PSM7751_RS04545 PSM7751_RS13915 N-acetyl-L- -glycerol 3- adenine PSM7751_RS03945 PSM7751_RS07460 E2 protein] N branched-chain dependent inorganic in tRNA enoyl-[acp] pyruvate hydroxypyruvate diphosphate kinase: nucleoside- a glycyl-[tRNA Gly ] selenate methionine Zn 2+ RS16055 Zn 2+ PSM7751_RS04010 IMP -lipoyl-L-lysine alpha-keto acid methylphosphonate menaquinol-11 formaldehyde MQH phosphate gln xanthine pyrophosphatase: sulfate 2 PSM7751_RS19060 diphosphate kinase: Gly diphosphate 5-triphosphate UTP adenine phosphoribosyltransferase: a tRNA dihydrolipoyl dehydrogenase PSM7751_RS09425 nucleoside- PSM7751_RS19060 adenylyltransferase diphosphatase: phosphoribosyltransferase: PSM7751_RS04880 dehydrogenase: subunit E2: diphosphate kinase: nucleoside- manganese- small subunit: PSM7751_RS09400 PSM7751_RS07790 PSM7751_RS08705 PSM7751_RS05385 phosphate 34 a cis-delta19- a (5Z)-3- 2+ 2+ CTP synthetase: dependent inorganic PSM7751_RS20640 α an L-phenylalanyl- 1-18:1-2- a guanine UTP 3'-UMP Zn RS09835 Zn RS16155 PSM7751_RS04010 diphosphate kinase: Aromatic Compound Biosynthesis adenosine 5'- -D-ribose-1- an acyl-[acyl- an N-terminal queuine DMKH2-10 (S)-citramalate oxaloacetate a palmitoyl-[acp] a malonyl-[acp] a malonyl-[acp] Phe lysophosphatidylethanolamine 37-methoxy-38- oxododec- PSM7751_RS00305 GMP dihydrolipoyl pyrophosphatase: methylphosphonate carrier protein] [tRNA ] L-lysyl-[protein] in tRNA NTP AMP PSM7751_RS04010 phosphoselenate lysophospholipase: tRNA guanosine(34) bifunctional citramalate synthase: methyl-C57:1-[acp] 4-carboxy-4-hydroxy- 5-enoyl-[acp] multifunctional 2',3'- CTP methionine-- dehydrogenase: PSM7751_RS09425 5-phosphate beta-ketoacyl-[acyl- beta-ketoacyl-[acyl- leucyl/phenylalanyl- cyclopropane-fatty- pyrophosphohydrolase: 3-oxoacyl-ACP chorismate biosynthesis I met PSM7751_RS05125an [apo BCAA PSM7751_RS06640 transglycosylase Tgt: demethylmenaquinone PSM7751_RS05220 2-oxoadipate reductase: cyclic-nucleotide 2'- CTP dTTP tRNA ligase: an [apo BCAA dehydrogenase carbon- carrier-protein] carrier-protein] tRNA--protein acyl-phospholipid PSM7751_RS17605 2+ 2+ 4-hydroxyphenylpyruvate dehydrogenase PSM7751_RS11225 aldolase/oxaloacetate phosphodiesterase/ Zn ZnuC Zn PSM7751_RS00200 6 phosphate synthase I: synthase I: transferase: lysophospholipase: methyltransferase/2- isopropylmalate/ synthase: PSM7751_RS15005 biosynthesis an L-methionyl- 6 E2 protein] N -S-[2- phosphorus lyase: nucleoside triphosphate E2 protein] N sulfolactate 34 decarboxylase: 5'-nucleotidase/ D-erythrose Met PSM7751_RS16480 PSM7751_RS07185 PSM7751_RS02215 a queuosine methoxy-6-polyprenyl-1,4- homocitrate/ PSM7751_RS15340 [+ 6 isozymes] [initiator tRNA ] methylpropanoyl]dihydrolipoyl- PSM7751_RS06330 PSM7751_RS16480 sn-glycero-3- pyrophosphohydrolase: a (3R,5Z)-3- RS11950 4-phosphate -dihydrolipoyl- degradation III selenite a 3-oxooctadecanoyl- L-phenylalanyl- guanine benzoquinol methylase: citramalate synthase: PSM7751_RS14095 3'-nucleotidase: initiator tRNA Met L-lysine acyl-carrier protein acyl-carrier protein a 3-oxoacyl-[acp] a tRNA Phe oleate in tRNA [+ 2 isozymes] hydroxydodec- tyr L-lysine carbon-phosphorus L-lysyl-[protein] phosphoethanolamine PSM7751_RS00870 PSM7751_RS19910 PSM7751_RS01510 3-deoxy-7- [acp] PSM7751_RS13915 a cis-methoxy- pyruvate 5-enoyl-[acp] predicted 3-sulfolactate lyase complex UMP phosphoheptulonate aromatic amino acid menaquinol-10 acetate pyruvate C59-meroacyl-[acp] uridine ABC sulfolactate subunit PhnI: Peptide Peptide Cell Structure Biosynthesis synthase: aminotransferase: ammonia transporter PSM7751_RS15075 dehydrogenase: PSM7751_RS06335 PSM7751_RS04255 Secondary Metabolite Biosynthesis oxidation III 5-phospho-α- of a peptide Fatty Acid and Lipid Biosynthesis 4-hydroxyphenylpyruvate branched-chain PSM7751_RS14115 selenodiglutathione RS12320 peptidoglycan biosynthesis I (meso-diaminopimelate containing) 3-deoxy- alpha-keto acid D-ribose 1,2- a [2-oxoglutarate- a ring-opened 7- phosphoenol an [HPr]- a 1-acyl-sn-glycero- 1-deoxy-L- a 3- a [glycerolipid]- a (5Z)-3- a (9Z)-3- A(H2) 3-sulfopyruvate DMK-12 uroporphyrinogen-III 3'-cmp Kdo transfer to lipid IV I D-arabino- myo-inositol cyclic phosphate dehydrogenase a sulfurated ARP glycero-tetrulose oxodocosanoyl- oxotetracos- oxooctacos- predicted A dehydrogenase SAM methylguanine in DNA pyruvate L-histidine 3-phosphocholine oleate palmitate biosynthesis II (bacteria and plants) UDP-N-acetyl-α-D-glucosamine heptulosonate biosynthesis autoinducer AI- Fermentation subunit E2: aspartate E2 protein] N 6 - [sulfur carrier] DNA- phosphoenolpyruvate- lysophospholipase: 4-phosphate bifunctional uroporphyrinogen-III [acp] 3-oxoacyl-ACP cyclopropane-fatty- 5-enoyl-[acp]3-oxoacyl-ACP 9-enoyl-[acp]3-oxoacyl-ACP multifunctional 2',3'- ABC palmitoleate CDP-diacylglycerol 6,7-dimethyl-8- Peptide Peptide CMP-Kdo lipid IV 7-phosphate 1 biosynthesis PSM7751_RS05385 aminotransferase: octanoyl-L-lysine lipoyl synthase: formamidopyrimidine -protein PSM7751_RS06640 demethylmenaquinone C-methyltransferase: reductase: acyl-phospholipid reductase: reductase: cyclic-nucleotide 2'- transporter biosynthesis I (from UDP-N-acetylglucosamine A D-glucopyranose ribityllumazine biosynthesis III glycosylase: phosphotransferase: PSM7751_RS02195 synthase: phosphodiesterase/ 3-deoxy-D-manno- 3-dehydroquinate pyruvate fermentation to propanoate I hydroxylamine PSM7751_RS15760 glutathioselenol PSM7751_RS03930a [2-oxoglutarate lysophospholipase: synthase: methyltransferase/2- PSM7751_RS09075 PSM7751_RS09075 PSM7751_RS09075 of a peptide an acetoacetyl-[acp] (5Z)-dodec-5-enoate) 1-carboxyvinyltransferase: 6-phosphate an acyl-[acyl- α-D-ribose 1,5- PSM7751_RS07780 5'-nucleotidase/ octulosonic acid synthase: aspartate PSM7751_RS13920 PSM7751_RS02215 methoxy-6-polyprenyl-1,4- uroporphyrinogen-III PSM7751_RS15340 [+ 6 isozymes] [+ 6 isozymes] RS11670 a (5Z)-dodec- an acyl-[acyl- PSM7751_RS00895 carrier protein] an unsulfurated dehydrogenase 2,6-diamino-4- an [HPr protein]- sn-glycero-3- PSM7751_RS00055 a (3R)-3-[+ 6 isozymes] a (3R,5Z)-3- a cis-delta9-3- PSM7751_RS04085 Metabolic Regulator Biosynthesis bisphosphate 5'-deoxyadenosine met an apurinic site π 6,7-dimethyl-8-(1- 3'-nucleotidase: DHAP carrier protein] transferase: aminotransferase: [sulfur carrier] E2 protein] N 6 hydroxy-5-(N-methyl) N -phospho- pyruvate a carboxylate benzoquinol methylase: C-methyltransferase: [+ 2 isozymes] Peptide RS20355 Peptide 3-oxoacyl-ACP 5-enoyl-[acp] UDP-N-acetyl-α-D- autoinducer synthase: oxaloacetate malate within DNA phosphocholine hydroxydocosanoyl- a [phospholipid]- hydroxytetracos- hydroxyC28:1- PSM7751_RS01510 beta-ketoacyl-[acyl- PSM7751_RS11820 PSM7751_RS08285 D-ribityl)lumazine PSM7751_RS13915 PSM7751_RS05200 reductase: glucosamine-enolpyruvate 3-dehydroquinate Ins(3)P PSM7751_RS05720 dehydrogenase: -lipoyl-L-lysine formamidopyrimidine L-histidine [acp] dihydrosterculate 5-enoyl-[acp] [acp] carrier-protein] α-Kdo-(2->6)-lipid IV ppGpp biosynthesis an N-acyl-L- urea cycle menaquinol-12 precorrin-2 cytidine PSM7751_RS09075 A mannosylglycerate PSM7751_RS08660 pyruvic oxime synthase I: UDP-N- homoserine lactone methylmalonyl-CoA L-cysteate hydrogen selenide [+ 6 isozymes] KDO transferase: type II 3- biosynthesis I inositol Peptide RS16160 Peptide a (7Z)-3-PSM7751_RS16480 acetylenolpyruvoylglucosamine carboxyltransferase: a (3R)-3- sn-glycerol PSM7751_RS11820 dehydroquinate pppGpp monophosphatase: arg ammonium RS12960 oxotetradec- an acyl phosphate reductase: PSM7751_RS12025 PSM7751_RS16575(S)-methylmalonyl- hydroxybutanoyl- dehydratase: GDP-α-D-mannose PSM7751_RS10940 a [pyruvate 2-methylacetoacetyl- 1-stearoyl- a 3- an (11Z)-3- 3-phosphate α-Kdo-(2->4)-α- bifunctional (p)ppGpp (S)-malate fumarate an L-phenylalanyl- an N-terminal DMKH2-13 a 3-oxoicosanoyl- [acp] 7-enoyl-[acp] PSM7751_RS09295 [+ 2 isozymes] CoA carbamoyl dehydrogenase a sulfurated oleate a palmitoyl-[acp] sn-glycerol an alcohol oxodocosanoyl- oxooctadec- a protein ala 3-oxoacyl-ACP Glu Kdo-(2->6)-lipid IV synthetase/guanosine- hydratase, class II: SAM [tRNA Phe ] arginyl-[protein] CoA [acp] ala UDP-N-acetyl-α-D-muramate A 6 acyl-CoA synthetase: NAD(P)-dependent predicted 3-hydroxyacyl-[acyl- guanosine 3'- methylmalonyl- nitrite pyruvate argininosuccinate phosphate synthase E2 protein] N - [sulfur carrier] leucyl/phenylalanyl- acetyl-CoA 3-phosphate bifunctional [acp] 3-oxoacyl-ACP 3-oxoacyl-ACP 11-enoyl-[acp]3-oxoacyl-ACP ATP-dependent alanine racemase: reductase: acyl-phosphate 3-dehydroshikimate 3',5'-bis(diphosphate) 3'- α myo-inositol PSM7751_RS03790 carrier-protein] diphosphate 5'- 2-O-( -D-mannosyl) CoA epimerase: lyase: large subunit: octanoyl-L-lysine lipoyl synthase: tRNA--protein PSM7751_RS02115 acetyltransferase: demethylmenaquinone alcohol dehydrogenase: reductase: reductase: reductase: Clp protease PSM7751_RS06270 ABC PSM7751_RS15005 glycerol 3-phosphate glutamate racemase: pyrophosphohydrolase: Peptide Peptide dehydratase FabA: UDP-N-acetylmuramate- lipid IV biosynthesis triphosphate 3'- -3-phosphoglycerate PSM7751_RS09630 PSM7751_RS08760 PSM7751_RS02315 PSM7751_RS03930 [+ 6 isozymes] PSM7751_RS15020 1-stearoyl- methyltransferase/2- PSM7751_RS04545 PSM7751_RS09075 PSM7751_RS09075 PSM7751_RS09075 transporter acyltransferase: A a [pyruvate transferase: proteolytic alanine racemase: [+ 6 isozymes] PSM7751_RS05000 PSM7751_RS15205 (R)-methylmalonyl- 2-palmitoyl- of a peptide RS12080 PSM7751_RS16475 -L-alanine ligase: diphosphatase: mannosyl-3- fumarate carbamoyl dehydrogenase PSM7751_RS07185 [+ 6 isozymes] methoxy-6-polyprenyl-1,4- NAD(P)-dependent [+ 6 isozymes] [+ 6 isozymes] [+ 6 isozymes] subunit: clpP PSM7751_RS11485 a (3R,7Z)-3- PSM7751_RS02625 a (3R)-3- CoA an unsulfurated diphosphate AMP oleoyl-CoA acyl-carrier protein a (3R)-3- a (3R)-3- a (3R,11Z)-3- PSM7751_RS15205 phosphoglycerate phosphate synthase 5'-deoxyadenosine met 6 L-phenylalanyl-L- sn-glycerol benzoquinol methylase: alcohol dehydrogenase: 3-hydroxyacyl-[acyl- hydroxytetradec- PSM7751_RS12040 UDP-N-acetyl- L-arginino- [sulfur carrier] E2 protein] N a tRNA Phe acetyl-CoA propanoyl-CoA hydroxydocosanoyl- hydroxyicosanoyl- hydroxyoctadec- a peptide a peptide D-ala D-glt hydroxytetradecanoyl- hydrogen sulfide L-ornithine arginyl-[protein] 3-phosphate carrier-protein] a 1-acyl-sn α-D-glucosamine shikimate phosphatase: succinate small subunit: -lipoyl-L-lysine PSM7751_RS13915 PSM7751_RS13945 predicted 7-enoyl-[acp] UDP-N-acetyl-α-D-muramoyl-L-alanine [acp] acyl-[acyl-carrier- biosynthesis I [acp] [acp] 11-enoyl-[acp] dehydratase FabZ: -glycerol 3- PSM7751_RS11030 methylmalonyl- PSM7751_RS07275 menaquinol-13 an aldehyde ABC 3-hydroxyacyl-[acyl- protein]--UDP-N- Peptide Peptide PSM7751_RS09885 phosphate shikimate kinase: GTP ppGpp 2-O-(α-D-mannosyl) CoA mutase: transporter carrier-protein] acetylglucosamine carbamoyl UDP-N-acetylmuramoyl- PSM7751_RS04080 -D-glycerate PSM7751_RS16605succinyl-CoA succinate cys of a peptide RS20125 a (2E)-but- dehydratase FabZ: L-alanine--D- O-acyltransferase: ornithine phosphate PSM7751_RS09885 nucleoside- argininosuccinate undecaprenyl-diphospho-N 3-benzyl-3,6-dihydroxy- 1-chloro-2,4- 1-stearoyl- 2251 a (6Z)-3- a double- 2-enoyl-[acp] glutamate ligase: UDP-3-O-[(3RPSM7751_RS09880)-3- shikimate 3- carbamoyltransferase: glycerol guanosine a 3-oxoglutaryl- diphosphate kinase: synthase: -acetylmuramoyl-L-alanyl-γ- UDP-N-acetyl-α-D-glucosamine 6-(hydroxymethyl) glutathione sinapate glutathione sn-glycerol L-saccharopine oxooctadec- MEP Peptide RS08530 Peptide 3-hydroxyacyl-[acyl- a 1,2-diacyl- PSM7751_RS12065 hydroxymyristoyl]-N- phosphate PSM7751_RS09550 dinitrobenzene a stearoyl-[acp] in 23S rRNA [acp] methyl ester helix DNA crotonyl-[acyl-carrier- PSM7751_RS19060 GDP 3-mercaptopyruvate PSM7751_RS17470 -diketopiperazine 4-coumarate- glutathione S- NAD(P)-dependent 23S rRNA 6-enoyl-[acp] DNA helicase II: carrier-protein] sn-glycerol acetyl-α-D-glucosamine bifunctional (p)ppGpp propionyl-CoA-- D-glutamyl-L-lysyl- D-alanine undecaprenyldiphospho- glutathione S- 3-phosphate saccharopine 3-oxoacyl-ACP 3-oxoacyl-ACP 1-deoxy-D-xylulose- protein] reductase: 3-phosphoshikimate 1- pyrophosphokinase: L-citrulline -CoA ligase: transferase: alcohol dehydrogenase: (guanosine(2251)-2'- PSM7751_RS12155 dehydratase FabA: 3-phosphate meso-diaminopimelate UDP-N-acetyl-α-D-muramoyl- UDP-3-O-[3- nucleoside- synthetase/guanosine- succinate CoA muramoylpentapeptide beta-N- transferase: dehydrogenase: reductase: reductase: 5-phosphate PSM7751_RS04870 carboxyvinyltransferase: PSM7751_RS15205 3-mercaptopyruvate PSM7751_RS14935 PSM7751_RS19345 PSM7751_RS13945 PSM7751_RS16475 L-alanyl-D-glutamate hydroxymyristoyl] N- diphosphate kinase: transferase: superpathway of glycolysis and the Entner-Doudoroff pathway acetylglucosaminyltransferase: PSM7751_RS19345 1-stearoyl-2- O)-methyltransferase PSM7751_RS14580 PSM7751_RS09075 PSM7751_RS09075 DNA helicase RecQ: reductoisomerase: predicted RS18755 PSM7751_RS15940 3',5'-bis(diphosphate) 3'- sulfurtransferase: PSM7751_RS04010 [+ 10 isozymes] stearoyl-sn NAD(P)-dependent RlmB: PSM7751_RS13680 PSM7751_RS09905 3 7 acetylglucosamine pyrophosphohydrolase: PSM7751_RS07550 PSM7751_RS12045 3-benzyl-3,6 -bis(glutathione)[+ 10 isozymes] [+ 2 isozymes] [+ 6 isozymes] [+ 6 isozymes] an unwound ABC a butanoyl-[acp] a trans-∆ -cis-∆ - 5-enolpyruvoyl- PSM7751_RS15080 ditrans,octacis-undecaprenyldiphospho- diphosphate AMP sinapoyl-CoA 2,4-dinitrophenyl- acyl-carrier protein a (3R)-3- a (3R,6Z)-3- 1-deoxy-D- Peptide UDP-N-acetylmuramoyl- D-glucopyranose -glycerol 3- alcohol dehydrogenase: PSM7751_RS06470 transporter Peptide D-ala deacetylase: shikimate 3- PSM7751_RS15205 UDP N-acetyl-(N-acetylglucosaminyl)muramoyl- - 6-(hydroxymethyl) S-glutathione 2-O- allysine Glu hydroxyglutaryl- hydroxyoctadec- double- xylulose 5- tetradecenoyl-[acp] a CDP- L-alanyl-D- phosphate PSM7751_RS04545 beta-ketoacyl-[acyl- PSM7751_RS12000 phosphate 6-phosphate hydrogen sulfide L-alanyl-γ-D-glutamyl-L-lysyl-D-alanine -diketopiperazine methylguanosine 2251 [acp] methyl ester 6-enoyl-[acp] stranded DNA phosphate of a peptide cis-∆ 7 -tetradecenoyl- diacylglycerol GDP carrier-protein] D-alanine--D- glutamate--2, 6- UDP-3-O-(3- Amine and Polyamine Degradation L-glyceraldehyde in 23S rRNA [acp]:NAD+ chorismate synthase: synthase I: alanine ligase: diaminopimelate ligase: hydroxymyristoyl) predicted RS07995 oxidoreductase: PSM7751_RS12110 -α-D-glucosamine PSM7751_RS18030 PSM7751_RS16480 PSM7751_RS12020 ectoine degradation ABC PSM7751_RS04870 UDP-3-O-(3- allantoin degradation urea degradation II adenine 2503 6-(hydroxymethyl) a [DNA]-3'- a 5'-phospho- (R)-2- 3-oxopentanoyl- Peptide Peptide creatinine + a 3-oxopimeloyl- a cis-delta15-3- transporter a 3-oxohexanoyl- UDP-N-acetyl-α-D-muramoyl-L-alanyl- hydroxymyristoyl) chorismate NAD succinyl-CoA xylitol a [protein] Ser/Thr an arachidoyl-[acp] repressor LexA a protein a (7Z)-tetradec- (Kdo) -lipid A biosynthesis I D-alanyl-D-alanine degradation I to ureidoglycolate II in 23S rRNA -7,8-dihydropterin hydroxyl [DNA] benzylsuccinate CoA of a peptide [acp] 2 γ-D-glutamyl-meso-2,6-diaminopimelate NAD(P)-dependent [acp] methyl ester oxo-C34:1-[acp] glucosamine N- glucose-6-phosphate ectoine (ammonia producing) 23S rRNA 2-amino-4-hydroxy-6- DNA ligase succinyl-CoA-- acetyl-CoA serine/threonine beta-ketoacyl-[acyl- 3-oxoacyl-ACP 3-oxoacyl-ACP 7-enoyl-[acp] α α urea alcohol dehydrogenase: HslU--HslV peptidase 3-oxoacyl-ACP -Kdo-(2->4)- - acyltransferase: 6-phospho isomerase: ectoine (adenine(2503)-C(2) hydroxymethyldihydropteridine (NAD(+)) LigA: benzylsuccinate acetyltransferase: protein kinase: reductase: reductase: repressor LexA: UDP-N-acetylmuramoyl- creatinine (S)-(+)-allantoin urease subunit alpha: carrier-protein] predicted beta-ketoacyl-[acyl- Kdo-(2->6)-lipid IV PSM7751_RS04580 D-glucono- PSM7751_RS03845 hydrolase DoeA: )-methyltransferase: diphosphokinase: PSM7751_RS20045 CoA-transferase: PSM7751_RS15020 PSM7751_RS13945 PSM7751_RS15700 ATPase subunit: reductase: A creatininase: synthase I: PSM7751_RS09075 PSM7751_RS09075 PSM7751_RS04940 RS08025 lauroyl tripeptide--D-alanyl- PSM7751_RS07500 PSM7751_RS17300 ABC PSM7751_RS09075 carrier-protein] UDP-2-N,3-O-bis[(3R)- 1,5-lactone PSM7751_RS04600 PSM7751_RS13455 PSM7751_RS15215 PSM7751_RS18715 [+ 6 isozymes] NAD(P)-dependent serine kinase: Peptide Peptide acyltransferase: (2S)-2-acetamido- PSM7751_RS12220 (7,8-dihydropterin- a 3- PSM7751_RS16480 a (3R)-3-[+ 6 isozymes] a cis-delta15-3-[+ 6 isozymes] transporter synthase I: D- alanine ligase: 3-hydroxytetradecanoyl]- [+ 2 isozymes] a 2-methyladenine 2503 NMN AMP [DNA] (R)-benzylsuccinyl- alcohol dehydrogenase: cleaved [+ 6 isozymes] PSM7751_RS05785 6-phosphogluconolactonase: 4-aminobutanoate creatininase: ammonium 5'-deoxyadenosine met 6-yl)methyl succinate propanoyl-CoA acetyl-CoA PSM7751_RS16870 oxodocosanoyl- a peptide of a peptide PSM7751_RS16480 α-Kdo-(2->4)-α-Kdo- PSM7751_RS12105 α-D-glucosamine allantoate in 23S rRNA CoA hydroxypimeloyl- hydroxyC34:1- repressor LexA a (3R)-3- PSM7751_RS03840 diphosphate PSM7751_RS04545 a [protein] (L-serine/L- a (9Z)-3- (2->6)-(lauroyl)-lipid IV PSM7751_RS16225 [acp] [acp] methyl ester [acp] hydroxyhexanoyl- A D-xylopyranose threonine) phosphate oxohexadec- UDP-N-acetyl-α-D-muramoyl-L- D-gluconate creatine predicted [acp] myristoyl transferase: 9-enoyl-[acp] alanyl-γ-D-glutamyl-meso-2,6- di-trans,octa-cis-undecaprenyl phosphate 6-phosphate ABC RS07840 3-hydroxyacyl-[acyl- PSM7751_RS00935 Peptide Peptide 3-oxoacyl-ACP diaminopimeloyl-D-alanyl-D-alanine lipid X phosphogluconate F6P L-2,4- transporter α α creatinase: 1498 carrier-protein] -D-Kdo-(2->4)- - diaminobutanoate L-proline betaine degradation decaprenyl-diphospho-N- UDP-N-acetyl- (1S,2R)-1- an [amino group carrier (3R,5S)-3- a (7Z)-3-oxo- a uracil reductase: dehydratase: PSM7751_RS12220 (S)-ureidoglycine linoleate a single a ribonucleoside 2-oxoglutarate an N-carbamoyl a cis-delta13-3- an unfolded of a peptide dehydratase FabA: D-Kdo-(2->6)-lipid A lipid-A-disaccharide fructose-1,6- acetylmuramoyl-pentapeptide α-D-glucosamine C-(indol-3- protein]-C-terminal-γ- hydroxy-1- hexadec-7- PSM7751_RS09075 PSM7751_RS10350 stranded DNA triphosphate ser D-amino acid oxo-C32:1-[acp] in 16S rRNA protein PSM7751_RS16475 bisphosphatase: diaminobutyrate- undecaprenyldiphospho- acyl-CoA synthetase: 2-oxoglutarate yl)glycerol (L-glutamyl)-L-glutamate pyrroline-5- enoyl-[acp] 16S rRNA [+ 6 isozymes] synthase: (S)-ureidoglycine DNA primase: 3-oxoacyl-ACP 3-oxoacyl-ACP -2-oxoglutarate sarcosine L-proline betaine muramoylpentapeptide beta-N- PSM7751_RS02115 dehydrogenase 3-phosphate tryptophan synthase acetylglutamate carboxylate pyrroline-5- N-carbamoyl-D-amino- (uracil(1498)-N(3))- Peptide RS12600 Peptide 3-hydroxyacyl-[acyl- a (3R,9Z)-3- undecaprenyldiphospho- PSM7751_RS09870 PSM7751_RS14925 aminohydrolase: PSM7751_RS04310 reductase: reductase: chaperonin GroL: KDGP transaminase: acetylglucosaminyltransferase: [+ 6 isozymes] E1 component: subunit beta: kinase: carboxylate reductase: acid hydrolase: methyltransferase: RS12015 carrier-protein] hydroxyhexadec- N-acetylmuramoyl-L-alanyl- β-D-fructose 1,6- PSM7751_RS18120 DNA primase: PSM7751_RS15005 PSM7751_RS09075 PSM7751_RS09410 lipid A disaccharide DHAP PSM7751_RS16070 PSM7751_RS12045 PSM7751_RS08680 PSM7751_RS15885 PSM7751_RS20785 PSM7751_RS09985 PSM7751_RS09120 PSM7751_RS02655 dehydratase FabZ: 9-enoyl-[acp] γ-D-glutamyl-meso-2,6- bisphosphate decaprenyl-pyrophosphoryl- PSM7751_RS00635 D-glyceraldehyde an [amino group carrier [+ 6 isozymes] [+ 6 isozymes] an N 3 - (S)-ureidoglycolate AMP diphosphate linoleoyl-CoA trp a (3R,7Z)-3- a cis-delta13-3- 3-hydroxyacyl-[acyl- diaminopimeloyl-D-alanyl-D-alanine tetraacyldisaccharide 2-keto-3- L-aspartate- ssDNA/pppN(pN) NADH CO succinyl-CoA [+ 2 isozymes] 1498 predicted PSM7751_RS09885 fructose bisphosphate UDP (N-acetylglucosamine)-N- 2 3-phosphate protein]-C-terminal- trans-4-hydroxy- a D-amino acid hydroxy-hexadec- hydroxyC32:1- methyluracil a protein semialdehyde hybrid carrier-protein] 4'-kinase: deoxygluconate 6- triose-phosphate n -1 γ-(5-phospho-L- in 16S rRNA ABC a (2E)-hex- undecaprenyldiphospho- aldolase: acetylmuramyl-(pentapeptide) L-proline 7-enoyl-[acp] [acp] Peptide Peptide dehydratase FabZ: PSM7751_RS18175 phosphate aldolase: isomerase: gly glutamyl)-L-glutamate transporter 2-enoyl-[acp] muramoylpentapeptide beta-N- PSM7751_RS05260 aspartate- N-methyl-L-proline D-proline betaine PSM7751_RS09885 PSM7751_RS10355 of a peptide acetylglucosaminyltransferase: lipid IV PSM7751_RS11255 semialdehyde RS18785 hexanoyl-[acyl-carrier- A 3-hydroxyacyl-[acyl- PSM7751_RS12045 Carbohydrate Biosynthesis dehydrogenase (non- N-methylproline an [amino group carrier protein]-C- UDP a cytidine 1402 a (3R,5Z)-3- 1-cis- protein] reductase: D-glyceraldehyde phosphorylating): demethylase: seleno-L- decanoate a 5-L-glutamyl- a uracil in DNA a 3-oxohexacosanoyl- a cis-delta11-3- predicted carrier-protein] terminal-γ-(L-ornithyl)-L-glutamate an amino acid in 16S rRNA hydroxy-tetradec- L-homoserine vaccenoylglycerol- PSM7751_RS04870 lipid II (meso diaminopimelate containing) 3-phosphate PSM7751_RS16195 PSM7751_RS12265 homocysteine [peptide] ribonucleotide-diphosphate [acp] oxo-C30:1-[acp] ABC dehydratase FabA: O-antigen building blocks biosynthesis (E. coli) GDP-mannose biosynthesis acyl-CoA synthetase: acetylornithine gamma- uracil-DNA 3-oxoacyl-ACP 16S rRNA 5-enoyl-[acp]3-oxoacyl-ACP 3-oxoacyl-ACP 3-phosphate Peptide Peptide PSM7751_RS16475 trehalose biosynthesis I glyceraldehyde- 5-methyltetrahydropteroyltriglutamate- reductase subunit alpha: homoserine O- transporter a hexanoyl-[acp] α PSM7751_RS02115 transaminase: glutamyltransferase: glycosylase: reductase: (cytidine(1402)-2'-O) reductase: reductase: a (2E,9Z)- UDP- -D- α-D- D-glucopyranose asp pro - homocysteine S-methyltransferase: PSM7751_RS04525 succinyltransferase: of a peptide fatty acid elongation -- saturated D-glucopyranose 3-phosphate [+ 6 isozymes] PSM7751_RS09545 PSM7751_RS15730 PSM7751_RS04920 PSM7751_RS09075 -methyltransferase: PSM7751_RS15005 PSM7751_RS09075 RS13115 galactose glucopyranose 6-phosphate D-glucopyranose an α-(5-L- hexadeca-2,9- UDP-galactopyranose 6-phosphate UDP-α-D-glucose dehydrogenase: PSM7751_RS04640 an [amino group carrier protein]- [+ 2 isozymes] ribonucleotide-diphosphate PSM7751_RS08425 PSM7751_RS19970 beta-ketoacyl-[acyl- glucose-6-phosphate 6-phosphate a peptide glutamyl)- [+ 6 isozymes] a 2'-O- [+ 6 isozymes] [+ 6 isozymes] 1-cis-vaccenoyl- Co 2+ Co 2+ dienoyl-[acp] 1-phosphateglucose-1-phosphate glucose-6-phosphate PSM7751_RS05060 diphosphate AMP decanoyl-CoA γ an apyrimidinic reductase subunit alpha: a (3R)-3- a (5Z)-3-oxo- a cis-delta11-3- O-succinyl-L- RS16510 carrier-protein] mutase: isomerase: alpha,alpha-trehalose- C-terminal- -(L-glutamate 5- uracil 1402 2-palmitoleoyl 2+ 2+ palmitoleoyl- an acetoacetyl-[acp] isomerase: SeMet amino acid site in DNA PSM7751_RS02820 hydroxyhexacosanoyl- methylcytidine tetradec-5- hydroxyC30:1- Mg Mg synthase I: PSM7751_RS01170 thymidylyltransferase: PSM7751_RS03845 phosphate synthase: semialdehyde-2-yl)-L-glutamate homoserine phosphatidate [acp]:NAD+ PSM7751_RS03845 13-DPG [acp] in 16S rRNA enoyl-[acp] [acp] PSM7751_RS16480 UDP-Galf PSM7751_RS17110 F6P α α PSM7751_RS13605 dUDP oxidoreductase: dTDP-α-D-glucose F6P , -trehalose a 3-oxooctanoyl- PSM7751_RS04870 glutamine--fructose- 6-phosphate phosphoglycerate Carboxylate Degradation Mg 2+ RS17020 Mg 2+ RS17745 dTDP-glucose mannose-1-phosphate 1402 a (9Z)-3-oxo- 1-cis- [acp] 4,6-dehydratase: 6-phosphate trehalose-6-phosphate kinase: 2-amino-6-[1-hydroxyethyl]- D-glucopyranose dCDP a cytidine guanylyltransferase/ ADP-α-D-glucose glutathione 4-hydroxy-2-nonenal a reduced + + chloroacetate a 3-oxotetracosanoyl- a cis-delta19-3- L(or D)-O- a palmitoleoyl-[acp] transaminase phosphatase: PSM7751_RS05255 propanoyl CoA 7-methyl-7,8-dihydropterin 6-phosphate NADP H in 16S rRNA octadec-9- vaccenoylglycerol- 3-oxoacyl-ACP a 3-oxoacyl-[acp] PSM7751_RS17100 mannose-6- pyruvate decarboxylation to acetyl CoA adrenodoxin ribonucleotide-diphosphate [acp] oxo-C38:1-[acp] phosphoserine PSM7751_RS13610 degradation I D-galactonate degradation 2-amino-4-hydroxy-6- alpha,alpha-trehalose- glutathione S- ferredoxin--NADP(+) haloacid dehalogenase, 3-oxoacyl-ACP 16S rRNA enoyl-[acp]3-oxoacyl-ACP 3-oxoacyl-ACP 3-phosphate reductase: (isomerizing): 3-phospho- reductase subunit alpha: 2+ 2+ dTDP-4-dehydro- phosphate isomerase: hydroxymethyldihydropteridine phosphate synthase: transferase: type II: PSM7751_RS16455 (cytosine(1402)-N(4) phosphoserine Mg RS07570 Mg PSM7751_RS09075 α PSM7751_RS11800 α α D-glycerate a [pyruvate dehydrogenase reductase: PSM7751_RS04525 reductase: reductase: reductase: 6-deoxy- -D- PSM7751_RS20565 , -trehalose diphosphokinase: PSM7751_RS13605 PSM7751_RS19345 haloacid dehalogenase, )-methyltransferase: phosphatase SerB: D-glucosamine propanoyl-CoA E2 protein] N 6 -lipoyl-L-lysine D-galactonate PSM7751_RS11320 PSM7751_RS09075 PSM7751_RS15005 PSM7751_RS09075 [+ 6 isozymes] glucopyranose D-mannopyranose phosphoglycerate pyruvate ribonucleotide-diphosphate PSM7751_RS18080 RS07850 acetyl/propionyl- PSM7751_RS15215 α,α-trehalose [+ 10 isozymes] an oxidized type II: PSM7751_RS08485 [+ 6 isozymes] 4 PSM7751_RS12125 [+ 6 isozymes] [+ 6 isozymes] 1,2-dicis- a (3R)-3- dTDP-4- 6-phosphate mutase (2,3- dehydrogenase [1-(2-amino-7-methyl-4-oxo- 4-hydroxy-2-nonenal- NADPH reductase subunit alpha: a (3R)-3- an N - a (3R,9Z)-3- a cis-delta19-3- 6-phosphate α ADP + + palmitoleate UDP- -D-glucuronate CoA carboxylase dihydrolipoyl 6-phosphate adrenodoxin glycolate 1402 vaccenoyl- K RS08750 K hydroxyoctanoyl- 3-oxoacyl-ACP dehydrorhamnose phosphoglucosamine diphosphoglycerate- (acetyl-transferring) pyruvate 7,8-dihydro-3H-pteridin- glutathione conjugate PSM7751_RS02820 hydroxytetracosanoyl- methylcytidine hydroxy-octadec- hydroxyC38:1- serine phosphomannomutase/ biosynthesis (from subunit alpha: dehydrogenase: 2-dehydro-3-deoxy- phosphatidate [acp] reductase: 3,5-epimerase: mutase: independent): E1 component 6-yl)]ethyl diphosphate [acp] in 16S rRNA 9-enoyl-[acp] [acp] RS19865 beta-ketoacyl-[acyl- phosphoglucomutase: UDP-glucose) PSM7751_RS16595 PSM7751_RS08705 D-galactonate CDP RS14730 3-hydroxyacyl-[acyl- PSM7751_RS15005 PSM7751_RS17095 PSM7751_RS14240 PSM7751_RS12450 (S)-methylmalonyl- subunit alpha: carrier-protein] PSM7751_RS14235 α 2-keto-3-deoxy- carrier-protein] [+ 6 isozymes] dTDP-4-dehydro- UDP- -D-glucose CoA dihydrolipoyl PSM7751_RS05270 cys D-glucosamine α 2-phospho- galactonokinase: RS11455 cys dehydratase FabA: synthase I: β -D-mannose UDP-glucose 6- dehydrogenase: a (7Z)-3- 2-pyrone-4,6- a 1-alkyl-sn RS20345 -L-rhamnose 1-phosphate D-glycerate methylmalonyl- 16-hydroxypalmitate an (R)-2- an oxidized c- MoO - N-acetyl- long chain a cis-delta17-3- PSM7751_RS16480 a (3R)-3- 1-phosphate dehydrogenase: PSM7751_RS18520 trans-caffeate nitric oxide carboxyphosphinopyruvate 2 -glycerol 3- PSM7751_RS16475 a 2,3,4-saturated dTDP-4- CoA epimerase: PSM7751_RS05125 halocarboxylate molybdopterin ATP polyphosphate oxohexacos- dicarboxylate hydroxyacyl-[acyl- UDP-N- phosphopyruvate 2-dehydro-3-deoxy- acyl-CoA synthetase: 4-coumarate- HAD family hydrolase: type cytochrome L-citrulline oxo-C36:1-[acp] phosphate fatty acyl-[acp] mannose-1-phosphate UDP-α-D-PSM7751_RS20555 a [pyruvate dehydrogenase nitrite reductase, carboxyvinyl- acetylornithine polyphosphate kinase 7-enoyl-[acp]3-oxoacyl-ACP 3-oxoacyl-ACP 2-pyrone-4,6- 3-hydroxyacyl-[acyl- carrier protein] dehydrorhamnose acetylglucosamine PSM7751_RS09630 D-galactonate cofactor 3-hydroxyacyl-[acyl- hydratase: a [pyruvate dehydrogenase E2 6 PSM7751_RS02115 -CoA ligase: PSM7751_RS20830 molybdenum cofactor 2: PSM7751_RS19975 an anion RS08835 carrier-protein] reductase: guanylyltransferase: glucuronate E2 protein] N -S- copper-containing: carboxyphosphonate deacetylase: reductase: reductase: dicarboxylate an anion RS02715 RS08040 carrier-protein] diphosphorylase/ PSM7751_RS03860 (R)-methylmalonyl- protein] N 6 -dihydrolipoyl-L-lysine 6-phosphate PSM7751_RS14935 guanylyltransferase dehydratase FabZ: PSM7751_RS20565 acetyldihydrolipoyl-L-lysine [+ 6 isozymes] HAD family hydrolase: PSM7751_RS03290 phosphorylmutase: PSM7751_RS04605 polyphosphate kinase PSM7751_RS09075 PSM7751_RS09075 hydrolase: PSM7751_RS17105 glucosamine-1- CoA 2-dehydro-3-deoxy-6- MobA: dehydratase FabZ: GDP-α-D- phosphoenol PSM7751_RS12525 a reduced c- PSM7751_RS06690 2: PSM7751_RS00320 PSM7751_RS09195 a 2-acyl-1-alkyl- PSM7751_RS09885 dTDP-β-L- phosphate N- 16-hydroxypalmitoyl- nitrite [+ 4 isozymes] a (3R,7Z)-3-[+ 6 isozymes] a cis-delta17-3-[+ 6 isozymes] (1E)-4-oxobut- RS03710 PSM7751_RS09885 mannose pyruvate methylmalonyl- phosphogalactonate AMP diphosphate diphosphate AMP trans-caffeoyl-CoA an (R)-2- type cytochrome 3-(hydroxyphosphinoyl) adenylyl PSM7751_RS02535 long chain rhamnose UDP-α-D-glucose CoA a halide anion hydroxyhexacos- hydroxyC36:1- 1-ene-1,2,4- sn-glycerol an anion a (2E)-oct- acetyltransferase: CoA mutase: aldolase: hydroxyacid pyruvate molybdenum acetate L-citrulline polyphosphate an anion RS08865 3-hydroxyacyl-[acyl- pyruvate kinase: 3-phosphate 2-enoyl-[acp] PSM7751_RS11795 biosynthesis I PSM7751_RS16605 PSM7751_RS18515 cofactor 7-enoyl-[acp] [acp] tricarboxylate carrier-protein] PRPP biosynthesis I PSM7751_RS12785 lipoate RS13150 N-acetyl-α-D- D-glucopyranose D-glyceraldehyde 3-oxoadipate RS01380 octanoyl-[acyl-carrier- dehydratase FabA: succinyl-CoA acetyl-CoA acetyltransferase: pyruvate protein] reductase: glucosamine 6-phosphate D-ribose 5- PSM7751_RS05125 3-phosphate degradation a 1-acyl-sn an anion RS07800 an anion PSM7751_RS16475 UDP-α-D-galactofuranose phosphomannomutase/ pyruvate 1-carboxyvinyl a peptide with a 5,6- phosphate glycerophosphoserine 20 a cis-delta21-3- pyridoxamine RS05830 PSM7751_RS04870 a trans-2- 1-phosphate phosphoglucomutase: 18-hydroxystearate 4-coumarate icosapentaenoate coenzyme A an N-terminal a myristoyl-[acp] dihydrouracil a stearoyl-[acp] -glycerol 3- a 2,3,4-saturated 2,3,4-saturated-fatty- biosynthesis phosphoribosylpyrophosphate 3-oxoadipate carboxyphosphonate oxo-C40:1-[acp] 5'-phosphate enoyl-[acyl- UDP-N- PSM7751_RS14235 acyl-CoA synthetase: 4-coumarate- long-chain fatty glycerophosphodiester carboxyvinyl- L-proline in tRNA pyridoxamine 5'- phosphate fatty acyl-[acp] acid-[acp] reductase: α-D-glucopyranose synthetase: PSM7751_RS01745 3-oxoadipate prolyl aminopeptidase: beta-ketoacyl-[acyl- tRNA beta-ketoacyl-[acyl- 3-oxoacyl-ACP an octanoyl-[acp] carrier protein] UDP-α-D-glucose acetylglucosamine PSM7751_RS02115 -CoA ligase: acid--CoA ligase: phosphodiesterase: carboxyphosphonate phosphate oxidase: PSM7751_RS16480 1-phosphate PRPP CoA-transferase: PSM7751_RS17580 carrier-protein] dihydrouridine(20/ carrier-protein] reductase: an anion RS11935 an anion RS02765 diphosphorylase/ citrate degradation [+ 6 isozymes] PSM7751_RS14935 PSM7751_RS14560 PSM7751_RS10945 phosphorylmutase: PSM7751_RS04865 RS13820 UDP-glucose 4-epimerase PSM7751_RS14420 prolyl aminopeptidase: synthase I: 20a) synthase DusA: synthase I: PSM7751_RS09075 beta-ketoacyl-[acyl- glucosamine-1- UTP--glucose- [+ 6 isozymes] sn-glycerol PSM7751_RS06690 GalE: PSM7751_RS17675 an acetyl-holo 3-oxoadipyl-CoA 18-hydroxystearoyl- ser PSM7751_RS01425 PSM7751_RS16480 PSM7751_RS05995 PSM7751_RS16480 a cis-delta21-3-[+ 6 isozymes] [+ 3 isozymes] a 1,2-diacyl- carrier-protein] 2,3,4-saturated fatty UDP-α-D-galactose phosphate N- 1-phosphate AMP diphosphate diphosphate AMP 4-coumaroyl-CoA icosapentaenoyl- 3-phosphate a 3-oxohexadecanoyl- a 3-oxoicosanoyl- RS16900 [citrate lyase acyl- citrate CoA carboxyphosphinopyruvate a peptide pro a uracil 20 in tRNA hydroxyC40:1- PLP sn-glycerol synthase I: acyl-[acp]:NAD+ acetyltransferase: uridylyltransferase: CoA [acp] [acp] an anion RS00215 an anion UDP-galactopyranose carrier protein] 3-oxoadipyl- 3-phosphate PSM7751_RS16480 oxidoreductase: PSM7751_RS11795 PSM7751_RS17670 [acp] gondoate biosynthesis mutase: PSM7751_RS01170 a citryl-holo CoA thiolase: PSM7751_RS04870 a 3-oxodecanoyl- (anaerobic) UDP-N-acetyl- α PSM7751_RS14430 RS13590 UDP-Galf UDP- -D-glucose [citrate lyase acyl- RS14275 [acp] α-D-glucosamine (15Z)- α-D-glucose (25S)-3- an oxidized carrier protein] GDP-α-D-glucose (S)-5-amino-3- acetyl-CoA a RNA-DNA hybrid palmitoleoyl-CoA 1-palmitoylglycerol succinyl-CoA tetracosenoate 6-phosphate oxocholest- coenzyme A a lignoceroyl-[acp] an octanoyl-[acp] a butanoyl-[acp] GGPP O c-type 3-oxoacyl-ACP a malonyl-[acp] an oleoyl-[acp] oxohexanoate GTP 3-phosphate 2 RS04875 citryl-CoA lyase: acyl-CoA synthetase: alpha,alpha-trehalose- 3-keto-5- 4-en-26-oate acyl-CoA synthetase: ribonuclease HI: acyl-CoA reductase: beta-ketoacyl-[acyl- beta-ketoacyl-[acyl- beta-ketoacyl-[acyl- beta-ketoacyl-[acyl- geranylgeranyl RS18885 acytochrome reduced long-chain fatty PSM7751_RS01350 PSM7751_RS02115 phosphate synthase: aminohexanoate PSM7751_RS15795 GTP cyclohydrolase PSM7751_RS15235 dehydrogenase: PSM7751_RS09075 carrier-protein] carrier-protein] carrier-protein] carrier-protein] reductase: H O c-type acid activation [+ 6 isozymes] PSM7751_RS13605 cleavage protein: [+ 2 isozymes] I FolE2: ribonuclease HII: PSM7751_RS14930 2 [+ 6 isozymes] synthase I: oxaloacetate (25S)-3- synthase I: synthase I: synthase I: PSM7751_RS17080 cytochromean oxidized PSM7751_RS16820 7,8- PSM7751_RS07525 PSM7751_RS13515 [+ 12 isozymes] 1-palmitoyl- RS04315 RS07940 a (3R)-3- an (11Z)-3-PSM7751_RS16480 a long-chain conversion of succinate to propanoate (Z)-15- α,α-trehalose oxocholest-4- PSM7751_RS16480 PSM7751_RS16480 PSM7751_RS16480 O c-type AMP diphosphate GDP (S)-3- dihydroneopterin formate a nucleoside 5'- (2E,9Z)- phytyl 2 oxo-icos-11- tetracosenoyl-CoA 6-phosphate acetoacetate en-26-oyl-CoA DNA a 3-oxohexacosanoyl- a 3-oxodecanoyl- a 3-oxohexanoyl- 2-myristoyl predicted hydroxydecanoyl- fatty acid acetate conversion Fatty Acid and aminobutanoyl-CoA hexadecenoyl-CoA diphosphate RS18900 acytochrome reduced enoyl-[acp] long-chain fatty 3'-triphosphate monophosphate [acp] [acp] [acp] phosphatidate ABC [acp] acid--CoA ligase: succinyl-CoA to acetyl-CoA Lipid Degradation H O c-type taurine taurine 3-oxoacyl-ACP 2 transporter 3-hydroxyacyl-[acyl- methylmalonyl- cytochromean oxidized reductase: PSM7751_RS14560 β of taurine carrier-protein] CoA mutase: acetate fatty acid -oxidation I O c-type PSM7751_RS15005 [+ 6 isozymes] propionyl-CoA-- an (R)-2- a 7,8-dihydro-8- 2-hydroxychromene- (7Z)- 1,6-anhydro-N- 2 RS03685 dehydratase FabA: a long-chain Cofactor, Prosthetic Group, Electron Carrier, and Vitamin Biosynthesis PSM7751_RS16605 18-hydroxyoleate glycerophosphoglycerol 1-aminocyclopropane- an aryl sulfate 1-palmitoylglycerol cytochrome RS02665 succinate CoA acetate--CoA ligase: halocarboxylate oxoguanine in DNA 2-carboxylate a dodecanoyl-[acp] hexadecenoyl-CoA acetyl-β-muramate a decanoyl-[acp] RS18890 a reduced PSM7751_RS16475 [+ 6 isozymes] fatty acyl-CoA a (3Z)-alk-3- 1-carboxylate 3-phosphate D-ribose RS04520 D-ribose a (3R,11Z)-3- transferase: PSM7751_RS16105 acyl-CoA synthetase: HAD family hydrolase: DNA- glycerophosphodiester 2-hydroxychromene- acyl-CoA anhydro-N- sulfatase: H O c-type enoyl-CoA 1-aminocyclopropane- beta-ketoacyl-[acyl- beta-ketoacyl-[acyl- 2 3-hydroxyacyl-[acyl- hydroxy-icos- cob(II)yrinate a,c-diamide PSM7751_RS07550 acetate--CoA ligase: PSM7751_RS02115 PSM7751_RS20830 formamidopyrimidine phosphodiesterase: 2-carboxylate dehydrogenase: acetylmuramic PSM7751_RS12310 ancytochrome oxidized [2Fe-2S] iron-sulfur cluster biosynthesis ubiquinol-8 biosynthesis (prokaryotic) guanylyl molybdenum pyridoxal 5'-phosphate biosynthesis I adenosylcobalamin biosynthesis from cobyrinate a,c-diamide II 1-carboxylate carrier-protein] carrier-protein] carrier-protein] biosynthesis II (late adenosylcobalamin (R)-methylmalonyl- PSM7751_RS07165 ∆ 3 ∆ 2 [+ 6 isozymes] HAD family hydrolase: glycosylase: PSM7751_RS10945 isomerase: PSM7751_RS14930 acid kinase: sulfatase: O c-type 11-enoyl-[acp] -cis- -trans-enoyl- synthase I: 2 cofactor biosynthesis propanoyl-CoA sn-glycerol deaminase: synthase I: + + dehydratase FabZ: cobalt incorporation) all-trans- acetyl-CoA PSM7751_RS12525 PSM7751_RS01740 [+ 12 isozymes] PSM7751_RS12335 cytochrome Na RS11085 Na 3-hydroxyacyl-[acyl- salvage from cobalamin CoA CoA isomerase: 18-hydroxyoleoyl- PSM7751_RS13920 glycerol PSM7751_RS10545 PSM7751_RS16480 N-acetyl-D-PSM7751_RS03830 PSM7751_RS16480 1-palmitoyl-2- RS07255 a reduced PSM7751_RS09885 MoO - D-erythrose cob(II)yrinate AMP diphosphate an (S)-2- an apurinic site 7,8-dihydro- 3-phosphate trans-O- (2E,7Z)- a 3- carrier-protein] uroporphyrinogen-III L-cysteine desulfurase 4-hydroxybenzoate octaprenyl 2 PSM7751_RS15125 CoA a halide anion a 3-oxotetradecanoyl- a phenol palmitoleoyl H O c-type 4-phosphate a,c-diamide 2-oxobutanoate muramate 6- oxododecanoyl- 2 dehydratase FabZ: diphosphate molybdopterin cob(I)alamin hydroxycarboxylate within DNA 8-oxoguanine hydroxybenzylidenepyruvate [acp] hexadecenoyl-CoA a (2E)-dec- uroporphyrinogen-III 4-hydroxybenzoate phosphate [acp] phosphatidate cytochromean oxidized cofactor molybdenum cofactor ATP:cob(I)alamin a (2E)-2- 2-enoyl-[acp] PSM7751_RS09885 C-methyltransferase: polyprenyltransferase: long-chain fatty O c-type Mn 2+ RS06260 Mn 2+ cysteine desulfurase: guanylyltransferase enoyl-CoA 2 PSM7751_RS02660 adenosyltransferase: a 2,3,4-saturated enoyl-CoA hydratase: RS07845 cytochrome decanoyl-[acyl-carrier- 3-hydroxyacyl-[acyl- PSM7751_RS05200 PSM7751_RS19410 3-octaprenyl-4- MobA: acid--CoA ligase: a reduced PSM7751_RS19305 4-phospho- coenzyme A PSM7751_RS15125 3-hydroxybutyryl- a 2,3,4- an (S)-2- a 2'- an N-acylated (7Z)- long chain 1-myristoylglycerol protein] reductase: carrier-protein] [+ 3 isozymes] hydroxybenzoate guanylyl cob(I)yrinate fatty acid PSM7751_RS14560 acyl-CoA 7-hydroxylaurate NADH pimeloyl-CoA H O c-type PSM7751_RS02535 adenosylcobalamin D-erythronate CoA epimerase: saturated (3R)-3- halocarboxylate deoxyribonucleoside [DNA] aliphatic-L- a behenoyl-[acp] tetradecenoyl-CoA a hexanoyl-[acp] 2 dehydratase FabA: precorrin-1 an S-sulfanyl-[L- a,c-diamide [+ 6 isozymes] dehydrogenase: 4'-phosphopantetheine ATP polyphosphate 3-phosphate ancytochrome oxidized PSM7751_RS04870 molybdenum PSM7751_RS01635 hydroxyacyl-CoA acyl-CoA synthetase: HAD family hydrolase: 5'-triphosphate amino acid NADH acyl-CoA exopolyphosphatase: pimeloyl-CoA chloride RS11985 chloride PSM7751_RS16475 cysteine desulfurase] erythronate- ATP:cob(I)alamin PSM7751_RS14930 DNA polymerase IV: N-acyl-L-amino acid beta-ketoacyl-[acyl- beta-ketoacyl-[acyl- O c-type cofactor PSM7751_RS02115 PSM7751_RS20830 pantetheine-phosphate pyrophosphatase: dehydrogenase: PSM7751_RS19645 dehydrogenase 2 uroporphyrinogen-III 4-phosphate PSM7751_RS14495 amidohydrolase: carrier-protein] carrier-protein] cytochrome a decanoyl-[acp] a (2E,11Z)-icosa- adenosyltransferase: [+ 12 isozymes] a 2,3,4- adenylyltransferase: PSM7751_RS12630 PSM7751_RS14930 large subunit: RS07865 a reduced C-methyltransferase: dehydrogenase: a 2,3,4-saturated [+ 6 isozymes] HAD family hydrolase: [+ 9 isozymes] PSM7751_RS13125 synthase I: exopolyphosphatase: synthase I: 2,11-dienoyl-[acp] 2-octaprenylphenol PSM7751_RS19305 saturated (3S)-3- reduced β- H O c-type PSM7751_RS05200 PSM7751_RS12525 PSM7751_RS05070 an aliphatic [+ 12 isozymes] PSM7751_RS16635 PSM7751_RS15120 1-myristoyl-2- 2 beta-ketoacyl-[acyl- PSM7751_RS18095 fatty acyl CoA hydroxyacyl-CoA 7-hydroxylauroyl- [DNA] a carboxylate PSM7751_RS16480 PSM7751_RS16480 2+ 2+ AMP diphosphate an (S)-2- 3'-dephospho-CoA nicotinamide D- AMP (2E,7Z)- 6-carboxyhex- ancytochrome oxidized Mo RS01210 Mo (2E,11Z)-icosa- an S-sulfanyl-[cysteine cob(I)yrinic acid a halide anion L-amino acid a 3-oxotetracosanoyl- long chain a 3-oxooctanoyl- palmitoleoyl carrier-protein] uroporphyrinogen-III 2-octaprenylphenol (3R)-3-hydroxy-2-oxo- 3-hydroxyacyl-CoA CoA hydroxycarboxylate ribonucleotide tetradecenoyl-CoA 2-enoyl-CoA O c-type 2,11-dienoyl- desulfurase]-[disordered- a,c-diamide [acp] polyphosphate [acp] phosphatidate 2 synthase I: C-methyltransferase: hydroxylase: 4 phosphooxybutanoate dehydrogenase: cytochrome form scaffold adenosyltransferase: adenosylcobalamin salvage from cobinamide II RS02555 a reduced PSM7751_RS16480 [acp] reductase: PSM7751_RS02195 PSM7751_RS15770 PSM7751_RS15125 protein] complex phosphoserine PSM7751_RS02130 H O c-type nitrate RS20310 nitrate a 3- PSM7751_RS04870 3-(all-trans 2 precorrin-2 aminotransferase: adenosyl- C1 Compound Utilization and Assimilation an N-formyl-L- (E)-4-hydroxy-3- glycine glycinecytochrome oxododecanoyl- cysteine desulfurase: -octaprenyl) cobinamide a 2,3,4-saturated 3-ketoacyl- a 2,3,4-saturated pristanate L-rhamnulose 1-phosphate an L-arginyl- an N-terminal L- a dimer of non-adjacent glutathione cis-vaccenoyl-CoA a [protein]-L- cerotoyl-CoA 1-palmitoylglycerol RS04420 PSM7751_RS18090 cobyrinate methionylaminoacyl- RX methylbut-2-en- a malonyl-[acp] betaine betaine [acp] a gondoyl-[acp] PSM7751_RS19410 benzene-1,2-diol adenosylcobalamin biosynthesis from cobyrinate a,c-diamide I fatty acyl CoA CoA thiolase: 3-oxoacyl-CoA [tRNA Arg ] glutamyl-[protein] 2'-deoxycytidines in DNA methionine 3-phosphate precorrin-2 C(20)- a,c-diamide acyl-CoA synthetase: bifunctional rhamnulose-1- tRNA glutathione S- 1-yl diphosphate acyl-CoA acetyl/propionyl- 3-oxoacyl-ACP bifunctional 3- 4-phosphooxy- ATP:cob(I)alamin formaldehyde oxidation PSM7751_RS18870 peptide deformylase: arginyltransferase: deoxyribodipyrimidine 4-hydroxy-3-methylbut- peptide-methionine beta-ketoacyl-[acyl- a short a short methyltransferase: a [cysteine desulfurase]- formate assimilation into 5,10- formaldehyde oxidation PSM7751_RS02115 phosphate aldolase/short- transferase: dehydrogenase: CoA carboxylase reductase: demethylubiquinol 3- cob(II)yrinate L-threonine cobyric acid adenosyltransferase: VII (THF pathway) PSM7751_RS15250 PSM7751_RS10490 photolyase: 2-en-1-yl diphosphate (R)-S-oxide reductase: carrier-protein] chain RS10740 chain PSM7751_RS02160 S-sulfanyl-[disordered- methylenetetrahydrofolate II (glutathione-dependent) [+ 6 isozymes] chain dehydrogenase: an N-terminal PSM7751_RS19345 PSM7751_RS14930 subunit alpha: glycine glycine PSM7751_RS09075 O-methyltransferase/ a,c-diamide 4-hydroxythreonine- synthase CobQ: PSM7751_RS19305 [+ 2 isozymes] PSM7751_RS04105 synthase: PSM7751_RS17855 synthase I: RS04425 form scaffold PSM7751_RS02020 L-arginiyl-L- a tRNA Arg betaine betaine fatty acid fatty acid PSM7751_RS07650 formaldehyde a L-methionylaminoacyl- [+ 10 isozymes] PSM7751_RS10560 [+ 12 isozymes] a protein-L- PSM7751_RS16480 PSM7751_RS16595 1-palmitoyl-2- [+ 6 isozymes] precorrin-3A protein] complex 2-polyprenyl-6- 4-phosphate adenosylcobinamide formate AMP formate a glutathione- 2-C-methyl-D- (2E,11Z)- a 3- 2-carboxy- (R)-1-amino- formaldehyde diphosphate pristanoyl-CoA DHAP (S)-lactaldehyde tRNA glutamyl-[protein] a cytosine in DNA HX methionine- cis-vaccenoyl a (3R)-3- hydroxyphenol dehydrogenase PdxA: FMNH formate-- acetyl-CoA S-conjugate erythritol-2,4- octadecenoyl-CoA oxodocosanoyl- cerotoyl-CoA biotin-carboxyl carrier protein assembly cysteine desulfurase: 2-propanol O adenosylcobyrate 2 (R)-S-oxide phosphatidate hydroxydodecanoyl- methylase: PSM7751_RS19625 adenosylcobinamide tetrahydrofolate ligase: cyclodiphosphate [acp] PSM7751_RS19410 cob(I)yrinate -2-phosphate a 5,10- a cation RS15560 a cation RS18265 [acp] PSM7751_RS17575 4-hydroxythreonine- amidohydrolase: PSM7751_RS08015 S-(hydroxymethyl) a [biotin carboxyl- an S-sulfanyl-[cysteine a,c-diamide adenosylcobinamide- methylenetetrahydrofolate an N 10 - 3-hydroxyacyl-[acyl- 2-methoxy- PSM7751_RS02785 glutathione Detoxification carrier protein]-L-lysine desulfurase]-S- ATP:cob(I)alamin 4-phosphate phosphate synthase: formyltetrahydrofolate a reduced a double 1-carboxyvinyl (5Z)- (R)-2- carrier-protein] precorrin-3B 6-(all-trans- bifunctional an L-arginyl- an N-terminal L- a [glutamine- dehydrogenase PdxA: (R)-1-amino- S-(hydroxymethyl) pyruvate ferredoxin [iron- NADP + H + 3-methylcatechol L-threonine 3- hydroxyglutaryl- Ins(2)P biotin--[acetyl-CoA- sulfanyl-[disordered- adenosyltransferase: PSM7751_RS16790 a tRNA precursor CTP ATP Arg stranded DNA carboxyphosphonate ATP tetradecenoyl-CoA dehydratase FabA: octaprenyl)phenol 5,6-dimethylbenzimidazole 2-propanol O methylenetetrahydrofolate bifunctional [tRNA ] aspartyl-[protein] synthetase]- O-phosphate RS17570 carboxylase] ligase: precorrin-3B C(17)- form scaffold PSM7751_RS19305 PSM7751_RS16185 adenosyl- adenosylcobyrate glutathione arsenate reactive oxygen species degradation pyruvate, sulfur] cluster ferredoxin--NADP(+) DNA/RNA carboxyvinyl- acyl-CoA catechol 2,3- CoA inositol a cation a cation PSM7751_RS16475 2-octaprenyl-6- D-glyceraldehyde dehydrogenase/ methylenetetrahydrofolate CCA tRNA arginyltransferase: L-tyrosine glutamine-synthetase 2-hydroxyglutaryl- methyltransferase: protein] complex (2S)-2-amino-3-oxo-4- cobinamide -2-phosphate dehydrogenase/ detoxification phosphate dikinase: reductase: carboxyphosphonate dehydrogenase: dioxygenase: threonine-phosphate monophosphatase: PSM7751_RS11630 methoxyphenyl cob(I)yrinic acid pyruvate nicotinate-nucleotide-- methenyltetrahydrofolate dehydrogenase/ PSM7751_RS10490 nuclease SfsA: adenylyltransferase: CoA dehydratase: 3-hydroxyacyl-[acyl- PSM7751_RS02165 phosphooxybutanoate 3-phosphate phosphate adenosylcobinamide- class III alcohol II (glutaredoxin) PSM7751_RS07440 nucleotidyltransferase: an N-terminal phosphorylmutase: PSM7751_RS14930 decarboxylase: RS01110 a [biotin carboxyl- hydroxylase: a,c-diamide dimethylbenzimidazole cyclohydrolase: an oxidizedPSM7751_RS11320 PSM7751_RS14710 a [glutamine PSM7751_RS14090 PSM7751_RS10940 carrier-protein] cysteine desulfurase: phosphate synthase: methenyltetrahydrofolate superoxide a tRNA PSM7751_RS17505 Arg PSM7751_RS10470 PSM7751_RS18720 carrier protein]-N 1-deoxy-D-xylulose-5- bifunctional phosphoribosyltransferase: dehydrogenase: phosphoenol L-arginiyl-L- a tRNA PSM7751_RS06690 [+ 12 isozymes] cis,cis-2-hydroxy- PSM7751_RS16795 ferric ferric PSM7751_RS19410 PSM7751_RS15770 adenosyltransferase: PSM7751_RS16260 cyclohydrolase: arsenate + NADPH ferredoxin [iron- synthetase]-O (R)-1-amino- (E)-glutaconyl- [+ 2 isozymes] FecE dehydratase FabZ: 6 precorrin-4 PSM7751_RS16790 diphosphate AMP H containing a aspartyl-[protein] a 5'-phosphooligonucleotide 3-(hydroxyphosphinoyl) (2E,5Z)- -biotinyl-L-lysine phosphate synthase: adenosylcobinamide PSM7751_RS06600 PSM7751_RS21240 pyruvate 4 6-oxohepta- dicitrate dicitrate a [cysteine 2-octaprenyl-6- PSM7751_RS02130 adenosyl- bifunctional PSM7751_RS16260 arsenate reductase superoxide dismutase: 3' CCA end sulfur] cluster pyruvate -(5'-adenylyl) tetradecenoyl-CoA 2-propanol O CoA myo-inositol PSM7751_RS09885 PSM7751_RS17965 kinase/ 2,4-dienoate precorrin-4 C(11)- desulfurase]-(S- methoxyphenyl adenosyl- 3-amino-1- α-ribazole cobinamide methylenetetrahydrofolate S-formylglutathione (glutaredoxin): PSM7751_RS05940 -L-tyrosine -2-phosphate a (2E)-dodec- 1-deoxy-D-xylulose adenosylcobinamide- bifunctional methyltransferase: sulfanyl) -[disordered- hydroxylase: cobyrinate hydroxyacetone 5'-phosphate phosphate PSM7751_RS01570 2 dehydrogenase/ methylenetetrahydrofolate hydrogen ferric ferric RS08355 2-enoyl-[acp] a [biotin carboxyl- PSM7751_RS02185 form scaffold PSM7751_RS07300 a,c-diamide 1-phosphate 5-phosphate phosphate S-formylglutathione arsenate reductase: RS04465 bifunctional methenyltetrahydrofolate dehydrogenase/ peroxide (S)-2-oxo-4- a [protein]-L- dicitrate dicitrate carrier-protein dimer]- 2-methoxy-6-all cobyric acid guanylyltransferase: hydrolase: succinyl-CoA acetoacetate quinoxaline-2- a proteinogenic a [ThiI sulfur-carrier ADP-D-ribose oleoyl-CoA an aromatic dodecanoyl-[acyl- protein] complex 5,6-dimethylbenzimidazole NaMN adenosylcobinamide cyclohydrolase: methenyltetrahydrofolate PSM7751_RS08185 acyl-carrier protein glutathione cys carboxynorspermidine hydroxy-4-carboxy- Ins(1)P 6 precorrin-5 pyridoxine 5'- PSM7751_RS08395 methionine GTP H O carrier-protein] N -biotinyl-L-lysine trans-octaprenyl- synthase CobQ: PSM7751_RS17230 arsenite carboxyl adenylate amino acid protein]-L-cysteine ADP-ribose 2 amino acid kinase/ PSM7751_RS14130 cyclohydrolase: catalase/ acyl CoA:acetate/3-ketoacid gamma- carboxynorspermidine 5-ureidoimidazoline acyl-CoA peptide-methionine inositol 1,4-benzoquinol PSM7751_RS07650 phosphate synthase: adenosylcobinamide- nicotinate-nucleotide-- acyl carrier protein: cysteine desulfurase: GTPase reductase: acetyl-CoA precorrin-6A synthase α adenosylcobinamide- PSM7751_RS14130 peroxidase HPI: CoA transferase subunit pyrophosphatase: dehydrogenase: aromatic amino acid ferric ferric PSM7751_RS15195 -ribazole a 5,10- formate PSM7751_RS05400 glutamyltransferase: PSM7751_RS19410 decarboxylase: OHCU decarboxylase: (S)-S-oxide reductase: monophosphatase: PSM7751_RS04870 carboxylase, acetyl-CoA (deacetylating): bifunctional (R)-1-amino- GDP dimethylbenzimidazole phosphate beta: PSM7751_RS06210 a [ThiI sulfur- PSM7751_RS06100 PSM7751_RS14930 ObgE: obgE aminotransferase: FecE a [cysteine desulfurase]- methenyltetrahydrofolate a 5,10- PSM7751_RS00955 a quinoxaline-2- PSM7751_RS15730an α-(γ-L- PSM7751_RS01200 PSM7751_RS18125 PSM7751_RS17860 PSM7751_RS10940 dicitrate dicitrate carboxyltransferase carboxylase biotin PSM7751_RS02205 demethylmenaquinone 2-propanol O adenosylcobyrate phosphoribosyltransferase: H O hydroxyl radical [+ 2 isozymes] PSM7751_RS15075 RS16925 guanylyltransferase: 2 [+ 3 isozymes] ala carrier protein]-S- [+ 12 isozymes] a protein-L- a dodecanoyl-[acp] [scaffold protein- methyltransferase/2- -2-phosphate bifunctional methenyltetrahydrofolate AMP carboxyl-[aryl- L-cysteinyl-glycine glutamyl)-L- D-ribofuranose an aromatic [+ 2 isozymes] subunit beta: carboxylase subunit: adenosylcobinamide- PSM7751_RS06600 PSM7751_RS08395 sulfanyl-L-cysteine norspermidine AMP (2E,9Z)- methionine- GDP H + (2Fe-2S)] complex pyridoxine 5'-phosphate acetoacetyl-CoA succinate carrier protein] (S)-(+)-allantoin 5-phosphate phosphate PSM7751_RS14770 PSM7751_RS07180 precorrin-6A methoxy-6-polyprenyl-1,4- adenosylcobinamide- GDP methylenetetrahydrofolate bifunctional arsenite O amino acid octadecenoyl-CoA 2-oxo-acid myo-inositol α-ribazole 2 (S)-S-oxide 2+ 2+ phosphate synthase: adenosylcobinamide- dehydrogenase/ Ni RS05600 Ni [+ 2 isozymes] benzoquinol methylase: pyridoxamine 5'- ribazoletransferase: methylenetetrahydrofolate beta-ketoacyl-[acyl- 5'-phosphate GDP methenyltetrahydrofolate formaldehyde a [carboxyl-carrier PSM7751_RS13915 PSM7751_RS16790 phosphate oxidase: PSM7751_RS06605 dehydrogenase/ carrier-protein] 6 6-methoxy-3- adenosyl- cyclohydrolase: oxidation IV (thiol- a peptide with 2-(1,2-epoxy-1,2- protein dimer]-N - a [co-chaperone]- PSM7751_RS04865 methenyltetrahydrofolate phosphatidylglycerophosphate an apo-[LYS2 L- a negatively a [protein]- synthase I: methyl-2-all- cobinamide adenosylcobinamide- O-succinyl-L- N-methyl-L- L-threo-3- 2-oxoglutarate RS11655 carboxybiotinyl-L-lysine [scaffold protein- PSM7751_RS16260 cyclohydrolase: independent) an N-terminal 2-aminoadipyl- coenzyme A dihydrophenyl) supercoiled DNA phe trp L-histidine Ni 2+ RS06235 Ni 2+ laurate precorrin-6B [+ 3 isozymes] adenosylcobalamin (1-octadecenoyl(9Z), 2-palmitoyl) homoserine tryptophan phenylserine PSM7751_RS16480 trans-octaprenyl- phosphate GDP PSM7751_RS16260 Xaa-L-prolineleucyl aminopeptidase: carrier-protein] acetyl-CoA isopropylmalate/ DNA topoisomerase (2Fe-2S)] complex bifunctional formaldehyde O-succinylhomoserine holo-ACP synthase: N-methyl-l- low specificity L- 2-(1,2-epoxy-1,2- aspartate histidine kinase: 1,4-benzoquinol bifunctional ribazoletransferase: phosphatidylglycerophosphatase PSM7751_RS14840 homocitrate/ IV subunit A: aromatic amino acid acyl-CoA synthetase: SSQ1 chaperone: PLP methylenetetrahydrofolate bifunctional formaldehyde sulfhydrylase: PSM7751_RS15180 tryptophan oxidase: threonine aldolase: dihydrophenyl)acetyl- aminotransferase: PSM7751_RS05075 2-octaprenyl-3- 5,6-dimethylbenzimidazole adenosylcobinamide PSM7751_RS06605 superpathway of heme A: PSM7751_RS03960 a holo-[LYS2 L- citramalate synthase: PSM7751_RS19325 aminotransferase: a 3-oxotetradecanoyl- PSM7751_RS02115 PSM7751_RS17655 b biosynthesis from dehydrogenase/ methylenetetrahydrofolate dehydrogenase, a peptide with [+ 3 isozymes] PSM7751_RS07530 PSM7751_RS12665 PSM7751_RS01730 CoA isomerase: PSM7751_RS15760 [+ 4 isozymes] acetate acetate methyl-6-methoxy- kinase/ a proteinogenic 2-aminoadipyl- 3',5'-ADP PSM7751_RS00870 [+ 2 isozymes] PSM7751_RS15075 a [protein]- [acp] [+ 6 isozymes] a [chaperone-ATP]- adenosylcobalamin salvage from cobinamide I uroporphyrinogen-III methenyltetrahydrofolate dehydrogenase/ glutathione- 1-oleoyl-2-palmitoyl- an N-terminal succinate L-homocysteine trp formaldehyde gly benzaldehyde PSM7751_RS04965 [+ 2 isozymes] (indol-3- RS16120 1,4-benzoquinol nicotinate-nucleotide-- adenosylcobinamide- adenosylcobalamin amino acid carrier-protein] 2-oxepin-2(3H)- (2R)-homocitrate a relaxed DNA keto- N-phospho- RS01105 precorrin-7 [co-chaperone]- cyclohydrolase: methenyltetrahydrofolate independent: phosphatidylglycerol L-proline yl)pyruvate 3-oxoacyl-ACP lauroyl-CoA phosphatidylcholine hydroxylase: dimethylbenzimidazole phosphate 5'-phosphate uroporphyrinogen-III ylideneacetyl-CoA L-histidine a cation a cation [scaffold protein- PSM7751_RS14130 cyclohydrolase: PSM7751_RS10095 phenylpyruvate reductase: biosynthesis VI PSM7751_RS15770 phosphoribosyltransferase: guanylyltransferase: cobinamide uroporphyrinogen biotin RS05760 biotin (2Fe-2S)] complex thiamine salvage III an N 10 - PSM7751_RS14130 formate PSM7751_RS09075 PSM7751_RS06600 PSM7751_RS08395 decarboxylase: Aromatic Compound Degradation a CDP- ATP:cob(I)alamin formyltetrahydrofolate 4-methyl-3- [+ 6 isozymes] choline 3-demethylubiquinol-8 α PSM7751_RS12495 a 5,10- 1-(3-sn-phosphatidyl)- a [Co(I) trimethylamine- 2,5-dichloro-trans a [protein]-L- an organic diacylglycerol SSQ1 chaperone -ribazole adenosylcobinamide- adenosyltransferase: an alkylated DNA an N-acylated- acryloyl-CoA 3-methylcatechol a (3R)-3- phosphatidylcholine thiamine coproporphyrinogen III formyltetrahydrofolate methylenetetrahydrofolate sn-glycerol 3-phosphate trimethylamine specific propanoyl-CoA phosphate -dienelactone phosphoenol dADP proline (ω = 180) oxoadipate- molecule precorrin-8x 5'-phosphate GDP adenosylcobalamin 4,5-dichlorocatechol D-amino acid a reduced hydroxytetradecanoyl- synthase: ATPase: bifunctional 3- thiamine PSM7751_RS19305 deformylase: corrinoid protein] DNA-3-methyladenine phosphate pyruvate crotonyl-CoA peptidylprolyl enol-lactone cytochrome P450: RS16750 protocatechuate degradation catechol degradation to trimethylamine D-aminoacylase: dienelactone catechol 2,3- H O c-type PSM7751_RS17655 degradation glycosylase: 3-oxoadipate 2 [acp] PSM7751_RS08130 precorrin-8X demethylubiquinol 3- diphosphokinase: PSM7751_RS14135 2-oxopent-4-enoate II phosphatidylglycerophosphatase methyltransferase: acyltransferase: hydrolase: pyruvate kinase: carboxylase/ isomerase: dioxygenase: PSM7751_RS04045 stearate biosynthesis adenosylcobinamide II (ortho-cleavage pathway) PSM7751_RS05500 enol-lactonase: RS12570 cytochrome 3-hydroxyacyl-[acyl- a phosphatidylcholine methylmutase: O-methyltransferase/ adenosylcobinamide- PSM7751_RS07605 4,5-dichlorobenzene- A: PSM7751_RS03960 PSM7751_RS02455 PSM7751_RS10180 PSM7751_RS12785 reductase: PSM7751_RS04905 cytochrome P450: an oxidized II (bacteria and plants) a [chaperone- a PSM7751_RS03900[methyl-Co(III) a DNA containing PSM7751_RS10110 PSM7751_RS14090 PSM7751_RS16435 carrier-protein] 2-polyprenyl-6- GDP thiamine formate an alkylated a carboxylate a D-amino acid propanoyl PSM7751_RS08545 [+ 3 isozymes] 2-hydroxy- PSM7751_RS11285 O c-type cobH an [2Fe-2S] bifunctional 1,2-diol protocatechuate catechol an L-1-phosphatidyl- dimethylamine trimethylamine-specific an apurinic/ 2 ADP]-[disordered- diphosphate 2,5-dichloromaleylacetate dATP pyruvate (R)-methylmalonyl- a [protein]-L- 4-methyl-3- + + dehydratase FabA: cluster protein hydroxyphenol ribazoletransferase: protoporphyrinogen IX catechol 2,3- nucleobase phosphate 6-oxohepta- an alcohol H RS09735 Hcytochrome form scaffold adenosylcobinamide N 10 -formyl-tetrahydrofolate biosynthesis protocatechuate sn-glycerol corrinoid protein] apyrimidinic site oxoadipate PSM7751_RS16475 a palmitoyl-[acp] hydrogenobyrinate methylase: PSM7751_RS06605 CoA proline (ω = 0) 2,4-dienoate protein] complex kinase/ 2,3-dichloro- 3,4-dioxygenase dioxygenase: RS08270 3-hydroxyacyl-[acyl- beta-ketoacyl-[acyl- PSM7751_RS17575 PSM7751_RS14090 cobyrinic acid a,c- non-chaperonin adenosylcobinamide- cis,cis-muconate subunit alpha: carrier-protein] carrier-protein] adenosylcobalamin a tetrahydrofolate HMS acyl-CoA hydrolysis phosphate PSM7751_RS16420 α (2S)- 38- + + synthase I: diamide synthase: molecular ubiquinol-8 5'-phosphate UDP-N-acetyl- -D-muramoyl- 3-aci- a [protein]- an acyl- a uridine (5Z)- succinate H RS06675 H dehydratase FabZ: D-alanyl-D-alanine a [protein]-L-lysine methylsuccinyl- acetyl-CoA phosphoenol L-dopa PSM7751_RS16480 PSM7751_RS02190 chaperone ATPase: guanylyltransferase: protoporphyrin IX [+ 2 isozymes] L-alanyl-γ-D-glutamyl-L-lysine nitropropanoate L-glutamine coenzyme A thr dGDP 40 in tRNA dodecenoyl-CoA biotin ATP semialdehyde PSM7751_RS09885 a 3-oxooctadecanoyl- 3-carboxy-cis nitronate carrier protein pyruvate acyl-CoA succinate- a 2,3,4-saturated hydrogenobyrinate PSM7751_RS17655 PSM7751_RS08395 Alcohol Degradation UDP-N-acetylmuramoyl- transglutaminase: CoA 3-oxoadipyl- low specificity L- tRNA [acp] methionine synthase: 2-chloro-2-(2-chloro- ,cis-muconate monooxygenase: holo-ACP synthase: 4,5-DOPA dehydrogenase: biotin--[acetyl-CoA- semialdehyde a (2E)-tetradec- fatty acyl CoA a,c-diamide an [Fe-S cluster a [disordered- adenosyl- ferrochelatase: tripeptide--D-alanyl- PSM7751_RS04810 CoA thiolase: threonine aldolase: pyruvate kinase: pseudouridine(38- acyl-CoA thioesterase PSM7751_RS04645 5-oxofuran-2-yl)acetate 3-carboxy- (2Z,4E)-2- PSM7751_RS15180 H + RS11885 H + RS18170 cobinamide PSM7751_RS17540 D- alanine ligase: PSM7751_RS12195 [+ 2 isozymes] PSM7751_RS12785 dioxygenase extradiol: 40) synthase TruA: PSM7751_RS14930 carboxylase] ligase: dehydrogenase 2-enoyl-[acp] 3-oxoacyl-ACP II: PSM7751_RS07225 cobaltochelatase biosynthesis form [Fe-S] cluster ethylene glycol hydroxyhexa- [unspecified a protein with an PSM7751_RS14430 PSM7751_RS01730 molybdenum cofactor biosynthesis adenosylcobalamin phosphate [+ 2 isozymes] glycerol and glycerophosphodiester degradation cis,cis-muconate acyl-carrier protein 3',5'-ADP 4-methyl-3- PSM7751_RS18635 PSM7751_RS00400 PSM7751_RS11630 (NADP(+)): gabD reductase: chaperone]-ATP scaffold protein] thiamine salvage II PSM7751_RS12105 degradation nitrite 3-oxopropanoate N 6 -(γ-glutamyl)- [+ 12 isozymes] biotinyl-5'- myristoyl-[acyl-carrier- [+ 2 isozymes] subunit CobS: degradation cycloisomerase: 2,4-dienedioate UDP-N-acetyl-α-D-muramoyl-L-alanyl- gly acetaldehyde dGTP pyruvate a pseudouridine 38- (2E,5Z)- PSM7751_RS09075 a 2,3,4-saturated bifunctional ferroheme b products] L-lysine crosslink oxoadipyl-CoA 4,5-seco-dopa adenylate succinate protein] reductase: PSM7751_RS11960 5,6-dimethylbenzimidazole NaMN PSM7751_RS16410 γ-D-glutamyl-L-lysyl-D-alanyl-D-alanine 40 in tRNA dodecenoyl-CoA fatty acid 4-amino-2-methyl-5- adenosylcobinamide H + PntB + PSM7751_RS04870 [+ 6 isozymes] [+ 2 isozymes] ethylene glycol a glycerophosphodiester 5-chloro-trans H a (3R)-3- ATP pyrimidinemethanol kinase/ bifunctional (2-carboxy- cob(II)yrinate nicotinate-nucleotide-- NAD(P)- glycerol -dienelactone 2,5-dihydro- RS01290 hydroxyoctadecanoyl- heme b biosynthesis bifunctional adenosylcobinamide- methylenetetrahydrofolate (3E)-2-oxohex- an [L-cysteine a myristoyl-[acp] gcv system: dependent alcohol dienelactone L-4-hydroxyphenylglycine- 32 sn-glycero-3- an N-terminal succinate a,c-diamide dimethylbenzimidazole a 7,8-dihydrofolate a 5-methyltetrahydrofolate glycerophosphodiester 5-oxofuran- a cytosine an L-arginyl- hydantoin DNA with lesion [acp] II (anaerobic) GTP hydroxymethylpyrimidine phosphate PSM7751_RS17055 dehydrogenase/ 3-enedioate L-arginyl-D-4- desulfurase]-S- 3-sulfino-L- arg a mercapturate a D-amino acid crotonyl-CoA salicylaldehyde cys phosphoribosyltransferase: serine dehydrogenase: hydrolase: 2-yl)-acetate in tRNA phosphoethanolamine Arg semialdehyde predicted beta-ketoacyl-[acyl- 3-hydroxyacyl-[acyl- guanylyltransferase: methenyltetrahydrofolate phosphodiesterase: glycerol kinase: sulfanyl-L-cysteine glycerophosphodiester [tRNA ] succinate- kinase/ PSM7751_RS06600 hydroxymethyltransferase: glyA PSM7751_RS13945 PSM7751_RS10110 4-carboxymuconolactone hydroxyphenylglycine-L-seryl- tRNA 2-thiocytidine(32) alanyl-[protein] N-acyl-L-amino acid dihydropyrimidinase: crotonyl-CoA excinuclease salicylaldehyde carrier-protein] cyclohydrolase: PSM7751_RS10945 PSM7751_RS18815 arginyltransferase: nitric oxide synthase: ABC carrier-protein] uroporphyrinogen-III GTP 3',8- phosphomethylpyrimidine PSM7751_RS08395 decarboxylase: L 4-hydroxyphenylglycine synthetase TtcA: phosphodiesterase: PSM7751_RS00520 carboxylase/ ABC subunit A: semialdehyde a sugar a sugar dehydratase FabA: a carboxy- cysteine desulfurase: NAD(P)- trypsin: PSM7751_RS10490 PSM7751_RS07340 amidohydrolase: D-amino-acid oxidase: dehydrogenase: transporter synthase I: uroporphyrinogen cyclase MoaA: kinase: PSM7751_RS06105 α-ribazole adenosylcobinamide- PSM7751_RS16260 a (6S)-5- 5-chloromaleylacetate PSM7751_RS10945 an N-terminal L- reductase: PSM7751_RS05115 dehydrogenase adenylated PSM7751_RS19410 dependent alcohol PSM7751_RS16430 PSM7751_RS15490D-4-hydroxyphenylglycine- PSM7751_RS20750an [L-cysteine PSM7751_RS13125 [+ 2 isozymes] PSM7751_RS13990 PSM7751_RS06565 of a sugar PSM7751_RS16475 sn-glycerol 2-oxopent- 32 sn-glycerol Arg PSM7751_RS16480 siroheme biosynthesis decarboxylase: PSM7751_RS11815 5'-phosphate GDP bifunctional formyltetrahydrofolate (4,5-dihydro- L-4-hydroxyphenylglycine- a 2-thiocytosine ethanolamine arginiyl-3-sulfino- a tRNA nitric oxide L-citrulline an L-cysteine- PSM7751_RS08545 [+ 2 isozymes] (NADP(+)): gabD RS05840 [small subunit of an [L-cysteine HMP-P dehydrogenase: 4-enoate L-seryl-L 4- desulfurase]- acetate a 2-oxo (2S)- 3-hydroxyacyl-[acyl- PSM7751_RS12495 (8S)-3',8-cyclo-7,8- 3-phosphate 5-oxofuran- L-arginine in tRNA 3-phosphate L-alanyl-[protein] S-conjugate N-carbamoylglycine DNA without salicylate succinate a 3-oxohexadecanoyl- molybdopterin methylenetetrahydrofolate 5-formyltetrahydrofolate PSM7751_RS04545 hydroxyphenylglycine L-cysteine carboxylate a sugar RS02275 a sugar carrier-protein] coproporphyrinogen III desulfurase]-S- dihydroguanosine 5-(2-hydroxyethyl) 2-yl)-acetate ethylmalonyl-CoA lesion [acp] uroporphyrinogen-III synthase] bifunctional adenosylcobinamide- methylenetetrahydrofolate dehydrogenase/ cyclo-ligase: glycolaldehyde dehydratase FabZ: sulfanyl-L-cysteine 5'-triphosphate -4-methylthiazole (2Z,4Z)-2-chloro- 3-oxoadipate uroporphyrinogen-III oxygen-independent hydroxymethylpyrimidine GDP reductase [NAD(P)H]: methenyltetrahydrofolate PSM7751_RS19090 3-oxoacyl-ACP PSM7751_RS09885 cyclic pyranopterin hydroxyethylthiazole 3-hydroxyhexa- enol-lactonase: C-methyltransferase: kinase/ ribazoletransferase: cyclohydrolase: 4-hydroxy-2- 516 reductase: coproporphyrinogen monophosphate PSM7751_RS00255 [+ 2 isozymes] 2,4-dienedioate catechol degradation to a nascent peptidoglycan a peptidoglycan with (L- a single- an N-terminal RNase G a uridine geranylgeranyl PSM7751_RS05200 kinase: PSM7751_RS06605 PSM7751_RS14130 DHAP PSM7751_RS16435 an L-arginyl- (S)-5-hydroxyisourate a CDP- sn-glycerol a sugar RS00080 a sugar a (2E)-octadec- III oxidase: phosphomethylpyrimidine a 5,10- a 5,10- with (L-alanyl-γ-D-glutamyl- alanyl-γ-D-glutamyl-meso stranded RNA 3-sulfo-L- nonenal-[Cys- 2-oxoglutarate D-ala degradation ser RS03580 PSM7751_RS09075 synthase MoaC: PSM7751_RS06120 5-chloromaleylacetate 2-oxopent-4-enoate I GTP [tRNA Arg ] diacylglycerol 3-phosphate in 16S rRNA chlorophyll a 2-enoyl-[acp] [+ 3 isozymes] PSM7751_RS03300 a thiocarboxylated kinase: PSM7751_RS06105 methylenetetrahydrofolate meso-2,6-diaminopimeloyl- -2,6-diaminopimeloyl- polyribonucleotide alanyl-[protein] Gly] conjugate substrate mRNA 16S rRNA [+ 6 isozymes] PSM7751_RS04930 4-methyl-5-(2- methenyltetrahydrofolate glycolate reductase: 3-oxoadipate arginyltransferase: aminopeptidase N: D-amino acid hydroxyisourate geranylgeranyl precorrin-1 [small subunit of cyclic adenosylcobalamin D-alanine) tetrapeptide D-alanine) tetrapeptide GTP cyclohydrolase nucleotidyltransferase: ribonuclease G: pseudouridine(516) L-serine a (3R)-3- steroyl-[acp] oxygen-independent phosphooxyethyl) bifunctional PSM7751_RS11145 catechol L,D-transpeptidase: PSM7751_RS10490 PSM7751_RS11900 aminotransferase: hydrolase: reductase: molybdopterin pyranopterin HMP-PP 5'-phosphate II: PSM7751_RS15825 PSM7751_RS15660 an N-terminal L- 4-hydroxy-2- PSM7751_RS00845 1-(3-sn- synthase: ammonia-lyase: predicted hydroxyhexadecanoyl- reductase: uroporphyrinogen-III coproporphyrinogen thiazole methylenetetrahydrofolate (2Z)-5-chloro-4- catechol 2,3- a nascent peptidoglycanPSM7751_RS07895 2,5-diamino-6-(5- PSM7751_RS12820 PSM7751_RS18130 PSM7751_RS17080 synthase] phosphate a nucleoside a single- arginiyl-3-sulfo- a tRNA Arg gly nonenal-[L- (S)-2-oxo-4- phosphatidyl) PSM7751_RS19105 PSM7751_RS07595 ABC [acp] PSM7751_RS04870 III oxidase: dehydrogenase/ hydroxyhex-2-enedioate dioxygenase: D-ala with L,D cross links (meso- formate phospho-D-ribosylamino) pyruvate D-glt CMP a sugar a sugar C-methyltransferase: diphosphate stranded RNA L-alanyl-[protein] Cys] conjugate -sn-glycerol a 16S rRNA chlorophyll a 3-hydroxyacyl-[acyl- thiamine phosphate PSM7751_RS14090 pyrimidin-4(3H)-one hydroxy-4-carboxy- an mRNA fragment pyruvate transporter PSM7751_RS05200 PSM7751_RS12590 methenyltetrahydrofolate diaminopimelate containing) 3-phosphate pseudouridine 516 RS14650 carrier-protein] a stearoyl-[acp] HMS 5-ureidoimidazoline of a sugar uroporphyrinogen-III synthase: folate transformations I cyclohydrolase: benzoate degradation II dehydratase FabA: protoporphyrinogen IX C-methyltransferase: PSM7751_RS19540 adenosylcobalamin PSM7751_RS16260 (aerobic and anaerobic) PSM7751_RS16475 geranylgeranyl formate-- a dimer of a sugar RS17120 a sugar PSM7751_RS02195 molybdopterin thiamine-phosphate a tetrahydrofolate bifunctional 2-maleylacetate [EntB aryl- an L-arginyl- 2,3- (S)-4-amino-5- acetate an organic 1-myristoylglycerol diphosphate biosynthesis tetrahydrofolate ligase: an acetyl-[acp] a malonyl-[acp] ferulate glutathione hypoglycin A coenzyme A a protein a PII protein UTP non-adjacent 3-hydroxyacyl-[acyl- diphosphorylase: benzoate 2-oxopent- [tRNA Arg ] oxopentanoate hydroperoxide 3-phosphate PSM7751_RS08015 methylenetetrahydrofolate formate carrier protein] thymidines in DNA diaminopropanoate carrier-protein] precorrin-2 PSM7751_RS06115 maleylacetate beta-ketoacyl-[acyl- feruloyl-CoA synthase: gamma- [protein-PII] glutamate-1- peroxiredoxin: stearate (2E,6E)-farnesyl dehydrogenase/ benzoate--CoA ligase: 4-enoate holo-ACP synthase: arginyltransferase: deoxyribodipyrimidine diaminopropionate acetate kinase: RS01645 dehydratase FabZ: reductase: carrier-protein] synthase PSM7751_RS00995 glutamyltransferase: PSM7751_RS10490 uridylyltransferase: semialdehyde PSM7751_RS14690 a sugar RS02725 a sugar siroheme synthase: protoporphyrin IX diphosphate methenyltetrahydrofolate PSM7751_RS19755 PSM7751_RS15180 photolyase: ammonia-lyase: PSM7751_RS01080 PSM7751_RS09885 an N 10 - PSM7751_RS11145 I: PSM7751_RS16480 PSM7751_RS08435 2,1-aminomutase: acyl-CoA synthetase: molybdopterin farnesyltranstransferase: thiamine cyclohydrolase: PSM7751_RS15730 a holo-[EntB aryl- an N-terminal Arg [+ 2 isozymes] PSM7751_RS11295 benzoyl-CoA diphosphate AMP feruloyl-CoA 3',5'-ADP a tRNA a uridylylated PSM7751_RS04105 PSM7751_RS15320 PSM7751_RS03595 PSM7751_RS02115 ferrochelatase: adenine PSM7751_RS02490 phosphate formyltetrahydrofolate an acetoacetyl-[acp] acyl-carrier protein L-cysteinyl-glycine hypoglycin B carrier protein] arginyl-[protein] dimyristoyl a (2E)-hexadec- siroheme synthase: PSM7751_RS14130 3-oxoadipate acetyl phosphate an alcohol dinucleotide PII protein a thymine in DNA pyruvate 5-aminolevulinate 2-enoyl-[acp] [+ 6 isozymes] PSM7751_RS17540 GGPP 10 phosphatidate predicted PSM7751_RS07485 molybdopterin an N - palmitoyl-[acyl-carrier- formyltetrahydrofolate ABC stearoyl-CoA sirohydrochlorin ferroheme b molybdenumtransferase formyltetrahydrofolate a sugar a sugar RS06740 bifunctional β transporter protein] reductase: MoeA: PSM7751_RS04935 bifunctional deformylase: N-acetyl- -D-glucosamine- a 5' triphospho- 4,8,12- thiamine O-acetyl-L- a proteinogenic (+)-7-epi- H O [DNA] of a sugar PSM7751_RS04870 MoO - methylenetetrahydrofolate methylenetetrahydrofolate L-valine degradation I Amino Acid Degradation 1,6-anhydro-N- 2 trimethyltridecanoyl- D-threo-isocitrate oxaloacetate isoquinoline siroheme synthase: 2 PSM7751_RS14135 methanethiol leukotriene-C4 VibB coenzyme A [mRNA] D-lysine diphosphate gcv system: L-leucine degradation I L-histidine degradation II homoserine amino acid jasmonoyl-CoA PSM7751_RS11295 molybdopterin dehydrogenase/ dehydrogenase/ acetyl-β-D-muramate acyl-CoA thioesterase: CoA isocitrate PSM7751_RS17055 O-acetylhomoserine gamma- beta-N- holo-ACP synthase: RNA DNA polymerase isoquinoline 1- a palmitoyl-[acp] cofactor methionine synthase: methenyltetrahydrofolate methenyltetrahydrofolate PSM7751_RS20960 dehydrogenase citrate (Si)-synthase: predicted siroheme synthase: aminocarboxypropyltransferase: glutamyltransferase: acetylhexosaminidase: PSM7751_RS15180 pyrophosphohydrolase: sterol carrier protein: D-amino-acid oxidase: III subunit epsilon: oxidoreductase: cyclopropane fatty acid phosphopantothenate biosynthesis I PSM7751_RS04645 cyclohydrolase: cyclohydrolase: val [+ 2 isozymes] (NADP(+)): PSM7751_RS04955 ABC predicted PSM7751_RS07485 tetrahydrofolate biosynthesis leu his PSM7751_RS09430 PSM7751_RS15730 PSM7751_RS10230 a holo-[VibB aryl- PSM7751_RS12480 PSM7751_RS17465 PSM7751_RS13990 PSM7751_RS17340 PSM7751_RS08900a sugar a sugar (CFA) biosynthesis [+ 2 isozymes] PSM7751_RS16260 PSM7751_RS16260 an α-(γ-L-glutamyl) 1,6-anhydro-N- 3',5'-ADP (+)-7-epi- PSM7751_RS18810 transporter ABC branched-chain histidine acetate met leukotriene-D4 GlcNAc carrier protein] a 5'-phospho- a nucleoside 5'- isoquinolin- choline choline siroheme 3-methyl-2- branched-chain -L-amino acid acetyl-β-muramate jasmonate 3-oxopristanoyl- 6-amino-2- citrate of a sugar transporter a [phospholipid] (7,8-dihydropterin- bifunctional bifunctional amino acid ammonia-lyase: [mRNA] 2-oxoglutarate monophosphate 2(1H)-one oxobutanoate tetrapyrrole biosynthesis a (6S)-5- amino acid CoA oxohexanoate of choline olefinic fatty acid 4-aminobenzoate 6-yl)methyl methylenetetrahydrofolate methylenetetrahydrofolate aminotransferase: PSM7751_RS13065 palmitate cyclopropane-fatty- II (from glycine) formyltetrahydrofolate aminotransferase: a sugar RS18555 a sugar dihydropteroatediphosphate dehydrogenase/ PSM7751_RS17935 urocanate acyl-phospholipid dehydrogenase/ PSM7751_RS17935 predicted synthase: NAD salvage pathway I methenyltetrahydrofolate methenyltetrahydrofolate 10 all-trans- acyl-CoA synthetase: synthase: branched chain 4a-hydroxy-N - + a phosphate 5-formyltetrahydrofolate urocanate hydratase: 1-myristoylglycerol [EntF L-seryl- FMN NAD(P)H H 4-guanidinobutyramide selenide choline sulfate acetamide ABC gly 7,8- PSM7751_RS07330 cyclohydrolase: cyclohydrolase: branched chain formyltetrahydrofolate heptaprenyl 4-hydroxybenzoate a myristoyl-[acp] coenzyme A L-allo-threonine met thiamine thiamine PSM7751_RS02115 PSM7751_RS15340 thiamine diphosphate 2-dehydropantoate serine cyclo-ligase: amino acid 3-phosphate carrier protein] monoester + PSM7751_RS14130 amino acid PSM7751_RS13055 diphosphate flavin reductase: predicted transporter [+ 6 isozymes] [+ 2 isozymes] biosynthesis I (E. coli) 5-aminolevulinic dihydropteroate NAD PSM7751_RS14130 aminotransferase: 4a-hydroxytetrahydrobiopterin 4-hydroxybenzoate low specificity L- amidase: selenide, water alkaline phosphatase: amidase: a [phospholipid] hydroxymethyltransferase: glyA PSM7751_RS19090 aminotransferase: holo-ACP synthase: aromatic amino acid choline-sulfatase: of thiamine acid synthase: PSM7751_RS08460 4-imidazolone- dehydratase: polyprenyltransferase: PSM7751_RS10880 threonine aldolase: PSM7751_RS15765 dikinase SelD: PSM7751_RS08965 ABC fatty acid containing 2-dehydropantoate bifunctional [+ 2 isozymes] 4-methyl-2- PSM7751_RS15180 aminotransferase: PSM7751_RS04635 a sugar a sugar palmitoyl-CoA PSM7751_RS10575 PSM7751_RS08460 5-propanoate a holo-[EntF [+ 4 isozymes] PSM7751_RS07745 transporter HMP-PP 2-reductase: folylpolyglutamate bifunctional L-tyrosine degradation I PSM7751_RS14670 PSM7751_RS02660 dimyristoyl PSM7751_RS01730 [+ 3 isozymes] PSM7751_RS05550 [+ 2 isozymes] [+ 3 isozymes] cyclopropane 5-aminolevulinate NADH oxopentanoate + PSM7751_RS15075 3-methyl-2- 10 3-heptaprenyl-4- acyl-carrier protein 3',5'-ADP L-seryl-carrier NAD(P) FMNH of a sugar thiamine phosphate PSM7751_RS00550 synthase/dihydrofolate imidazolonepropionase: an N -formyl- phosphatidate 2 acetaldehyde gly pyrophosphatase: methylenetetrahydrofolate a 5,10- hydroxybenzoate protein] 4-guanidinobutanoate 4-(methylsulfanyl) selenophosphate an alcohol choline acetate RS18790 synthase: oxobutanoate 7,8-dihydrofolate β-alanine delta-aminolevulinic synthase: NAD+ synthetase, PSM7751_RS12630 a 5,10- dehydrogenase/ methenyltetrahydrofolate PSM7751_RS13070 -2-oxobutanoate PSM7751_RS19540 (R)-pantoate a 5-methyltetrahydrofolate a sugar RS20500 a sugar acid dehydratase: PSM7751_RS14775 glutamine dependent: methylenetetrahydrofolate methenyltetrahydrofolate heme a biosynthesis tyr Amine and Polyamine Biosynthesis N-formimino- aromatic amino acid thiamine-phosphate PSM7751_RS19495 7,8-dihydrofolate nicotinate adeninePSM7751_RS09605 cyclohydrolase: NMN isovaleryl-CoA L-glutamate all-trans- diphosphorylase: methylenetetrahydrofolate aminotransferase: 10 dihomo γ- a D-5-monosubstituted pantoate--beta- monoglutamate dinucleotide PSM7751_RS14130 an N - an L-methionyl- 1-palmitoylglycerol a peptide with a H O 2-hydroxyisobutyramide α-D-lyxopyranose propionamide glyoxylate porphobilinogen reductase [NAD(P)H]: ferroheme b isobutanoyl-CoA PSM7751_RS15075 hexaprenyl 4-hydroxybenzoate a myristoyl-[acp] 2 ethylphosphate GGPP ectoine biosynthesis PSM7751_RS06115 alanine ligase: isovaleryl-CoA formimidoylglutamate formyltetrahydrofolate [initiator tRNA Met ] 3-phosphate leader sequence linolenoyl-CoA hydantoin thiamine nicotinic acid protoheme IX 4-hydroxyphenylpyruvate diphosphate acyl-CoA thioesterase: D-lyxose/D- RS18760 RS19815 spermidine biosynthesis I PSM7751_RS14890 trans, trans-farnesyl PSM7751_RS00255 dehydrogenase: deiminase: methionyl-tRNA 4-hydroxybenzoate signal peptidase: amidase: HyuE hydantoin alkaline phosphatase: amidase: phosphate hydroxymethylbilane mononucleotide farnesyltransferase: PSM7751_RS20960 mannose family phytoene synthase: malate synthase G: diphosphate biosynthesis PSM7751_RS11780 PSM7751_RS00925 formyltransferase: polyprenyltransferase: PSM7751_RS12235 PSM7751_RS15765 racemase: PSM7751_RS12805 PSM7751_RS15765 asp synthase: adenylyltransferase: PSM7751_RS07860 1-palmitoyl- [+ 2 isozymes] sugar isomerase: PSM7751_RS05215 PSM7751_RS17635 glutathione-glutaredoxin an N-formyl- PSM7751_RS15245 PSM7751_RS02660 [+ 3 isozymes] PSM7751_RS15305 [+ 2 isozymes] [+ 3 isozymes] SAM (R)-pantothenate PSM7751_RS12490 a 7,8-dihydrofolate PSM7751_RS16350 ferroheme o 3-methylcrotonyl- N-formyl- 3-hexaprenyl-4- acyl-carrier protein 2-myristoyl a leader sequence a peptide di-homo-γ- PSM7751_RS15240 aspartate kinase: redox reactions L-methionyl- a tetrahydrofolate 2-hydroxy-2- an L-5-monosubstituted IPP methylacrylyl-CoA CoA L-glutamate hydroxybenzoate phosphatidate linolenate ethanol 15-cis-phytoene propanoate (S)-malate PSM7751_RS16060 preuroporphyrinogen 4-amino-2-methyl-5- met methylpropanoate hydantoin D-xylulose pantothenate kinase: NaMN nicotinamide heme A synthase: 3-methylcrotonyl- homogentisate [initiator tRNA ] aspartate kinase: thiamine diphosphomethylpyrimidine GSSG N-formylglutamate RS16150 PSM7751_RS11625 nicotinamidase: PSM7751_RS19530 3-hydroxy-isobutyryl- CoA carboxylase: RS02285 PSM7751_RS07775 putrescine dAdoMet diphosphate biosynthesis glutathione- amidohydrolase: L-aspartyl- PSM7751_RS13730 CoA hydro-lyase: PSM7751_RS11755 (R)-4'- DMAPP disulfide reductase: PSM7751_RS14500 3-[(3aS,4S,7aS)-7a-methyl- all-trans- a long-chain 2-(4-hydroxyphenyl) (4Z)-2-oxohept- 3-[(7'-methylthio) (5R)-5-benzyl- 1-oleyl-2-lyso- 4-phosphate spermidine synthase: a tetrahydrofolate AIR ferroheme i PSM7751_RS13925 1-palmitoylglycerol an unsulfurated H O β-D-galactose trans-dienelactone phosphopantothenate nicotinate methylcrotonoyl- [+ 4 isozymes] 1,5-dioxo-octahydro-1H coenzyme A decaprenyl 4-hydroxybenzoate a palmitoyl-[acp] cys 2 phosphomethylpyrimidine PSM7751_RS02105 3-phosphate [sulfur carrier] fatty acyl-CoA -2-oxoacetate 4-enedioate heptyl]malate hydantoin phosphatidate PSM7751_RS21000 farnesyl-diphosphate (S)-3-hydroxy- CoA carboxylase: 4-maleyl- -inden-4-yl]propanoate diphosphate acyl-CoA thioesterase galactose mutarotase: aspartate- uroporphyrinogen-III phosphoribosyltransferase: synthase ThiC: glutathione heme A synthase: acyl-CoA synthetase: 4-hydroxybenzoate cysteine desulfurase: benzoylformate 2-oxo-hepta-3-ene-1,7- dienelactone 3-isopropylmalate HyuE hydantoin synthase: isobutanoyl-CoA PSM7751_RS11770 Glu acetoacetate PSM7751_RS15795 II: PSM7751_RS07225 PSM7751_RS18505 semialdehyde spermidine NAD PSM7751_RS13720 PSM7751_RS06125 PSM7751_RS19530 polyprenyltransferase: PSM7751_RS19410 decarboxylase: dioic acid hydratase: hydrolase: dehydrogenase: racemase: PSM7751_RS17960 [+ 2 isozymes] aldose epimerase: RS13710 RS00500 dehydrogenase: nicotinate HMP-P 3-methylglutaconyl- 3-[(3aS,4S,7aS)-7a-methyl-[+ 2 isozymes] PSM7751_RS02660 dipalmitoyl a sulfurated PSM7751_RS18570 PSM7751_RS09185 PSM7751_RS10110 PSM7751_RS12390 PSM7751_RS15305 phosphorylation and 3-decaprenyl-4- acyl-carrier protein ala a long-chain PSM7751_RS18070 PSM7751_RS19505 folate polyglutamylation geranyl S-adenosyl-L-methionine cycle I hydroxyferroheme i CoA 1,5-dioxo-octahydro-1H- phosphatidate [sulfur carrier] (4S)-4-hydroxy-2- 10-(methylthio)- (5S)-5-benzyl- dioleoyl transhydrogenation hydroxybenzoate fatty acid 4-hydroxybenzaldehyde 2-maleylacetate diphosphate bifunctional inden-4-yl]propanoyl-CoA oxoheptanedioate α-D-galactose 2-oxodecanoate hydantoin phosphatidate aspartate- + a reduced (S)-3-hydroxy- 4-fumaryl- NAD farnesyl-diphosphate hydroxymethylpyrimidine semialdehyde a tetrahydrofolate glutaredoxin isobutanoate acetoacetate NAD kinase: synthase: kinase/ SAM dehydrogenase: putrescine 3-hydroxyisobutyrate fumarylacetoacetase: all-trans- an N-acetyl-β- PSM7751_RS01710 bis(guanylyl molybdenum PSM7751_RS17960 phosphomethylpyrimidine 6 37 a double nicotinate adenine (S)-2- L-gulono- RS00765 PSM7751_RS14860 biosynthesis III dehydrogenase: HMG-CoA N -dimethylallyladenosine a sulfurated a cis- 1-palmitoylglycerol palmitoyl-CoA H O 3-sulfocatechol Kdo CTP 3-ethylmalate RS20120 + kinase: PSM7751_RS06105 ferroheme a PSM7751_RS15135 nonaprenyl 4-hydroxybenzoate D-hexosaminide 2 NADP serine formate-- bifunctional cofactor) biosynthesis in tRNA vaccenoyl-[acp] 3-phosphate stranded DNA dinucleotide hydroxyglutarate 1,4-lactone (2E,6E)-farnesyl methionine PSM7751_RS05105 fumarylacetoacetate [sulfur carrier] diphosphate beta-N- acyl-CoA thioesterase catechol 2,3- 3-deoxy-manno- L-aspartate- hydroxymethyltransferase: glyA tetrahydrofolate ligase: folylpolyglutamate MoO - two reduced hydroxymethylglutaryl- 4-hydroxybenzoate hydroxyglutarate 3-isopropylmalate L-ornithine NAD(P)(+) 2 diphosphate HMP-PP adenosyltransferase: (S)-methylmalonate- hydrolase: acetylhexosaminidase: II: PSM7751_RS07225 dioxygenase: DNA gyrase subunit A: octulosonate NAD+ synthase: gluconolactonase: semialdehyde PSM7751_RS08015 synthase/dihydrofolate molybdopterin cysteine residues CoA lyase: polyprenyltransferase: oxidase: dehydrogenase: PSM7751_RS16500 6 PSM7751_RS09605 PSM7751_RS18510 ornithine transhydrogenase: a 5,10- semialdehyde PSM7751_RS11745 PSM7751_RS11010 2-methylsulfanyl-N - 1-palmitoyl-2- PSM7751_RS10230 [+ 2 isozymes] PSM7751_RS14090 PSM7751_RS19510 cytidylyltransferase: diaminobutyrate- synthase: cofactorbis(molybdenum in a protein an unsulfurated PSM7751_RS02660 an N-acetyl-β- (2Z,4E)-2- PSM7751_RS14120 PSM7751_RS12390 decarboxylase: PSM7751_RS06675 methylenetetrahydrofolate an N 10 - PSM7751_RS14775 met 5'-deoxyadenosine dimethylallyladenosine 37 3-nonaprenyl-4- acyl-carrier protein cis-vaccenoyl an alcohol palmitate PSM7751_RS20625 SAH [sulfur carrier] sulfite hydroxyhexa- a negatively + -2-oxoglutarate cofactor) synthase: thioredoxinmet pathway NAD phosphorylation and dephosphorylation methylmalonate- acetoacetate fumarate acetoacetate phosphatidate D-hexosamine CMP-Kdo NAD 2-oxoglutarate 2-oxovalerate L-gulonate RS07565 RS06025 PSM7751_RS08580 NAD(P) bifunctional formyltetrahydrofolate L-proline degradation in tRNA hydroxybenzoate 2,4-dienedioate supercoiled DNA transaminase: putrescine bis(molybdenumPSM7751_RS02535 semialdehyde transhydrogenase folylpolyglutamate PSM7751_RS16070 bifunctional a tetrahydrofolate menaquinol-7 biosynthesis subunit beta: pntB cofactor) di-trans,poly-cis an oxidized NAD + dehydrogenase synthase/dihydrofolate folylpolyglutamate 5-methyltetrahydropteroyltriglutamate- (S)-3-amino-2- pro peptidoglycan L-2,4- molybdenum cofactor all-trans- -undecaprenyl (CoA acylating): a [glycine-cleavage 1-stearoyl- peptidoglycan 6-oxo-1,4,5,6- dCTP synthase: synthase/dihydrofolate - homocysteine S-methyltransferase:thioredoxin methylpropanoate an isoprenoid an acyl-[acyl- stearoyl-CoA H O citrate reduced riboflavin pyruvate ethanol diaminobutanoate NADPH 2-carboxy-1,4- phosphate biosynthesis PSM7751_RS05085 bifunctional proline SAM complex H protein] a sulfurated [sulfur carrier] 4-hydroxybenzoate sn-glycerol tetrapeptide, tetrapeptide, 2 a protein PSM7751_RS14775 synthase: guanylyltransferase heptaprenyl diphosphate carrier protein] tetrahydronicotinate 2'-deoxycytidine naphthoquinol PSM7751_RS04640 dehydrogenase/L- 6 glycan chain 1 glycan chain 2 acyl-CoA thioesterase diaminobutyrate MobA: diphosphate (2E,6E)-farnesyl L-methionine degradation N -octanoyl-L-lysine 4-hydroxybenzoate 3-phosphate L,D-transpeptidase: metalloprotease TldD: 6-hydroxynicotinate flavin reductase: catalase/ RS04990 a 5,10- PSM7751_RS14775 [+ 3 isozymes] S-ribosyl-L- NAD(P)(+) lipoyl synthase: II: PSM7751_RS07225 aconitate hydratase pyruvate carboxylase: 5'-triphosphate RS08060 menaquinol-8 biosynthesis PSM7751_RS02535 diphosphate thioredoxinL-homocysteine reductase: glutamate gamma- I (to L-homocysteine) polyprenyltransferase: PSM7751_RS07895 reductase: PSM7751_RS10880 peroxidase HPI: acetyltransferase: methylenetetrahydrofolate an N 10 - di-trans,poly-cis- homocysteine transhydrogenase: hydrogencarbonate PSM7751_RS03930 peptidoglycan PSM7751_RS07870 1: PSM7751_RS05795 PSM7751_RS12160 deaminase: bis(guanylyl demethylmenaquinol-7 PSM7751_RS06010 alkaline phosphatase: semialdehyde a [glycine-cleavage PSM7751_RS02660 a 1-stearoyl 2- [+ 2 isozymes] PSM7751_RS00955 PSM7751_RS16075 lipoate biosynthesis decaprenylcistransferase: PSM7751_RS06675 NAD kinase: an unsulfurated PSM7751_RS00565 [+ 6 isozymes] PSM7751_RS10205 formyltetrahydrofolate PSM7751_RS04635 dehydrogenase: 5'-deoxyadenosine met complex H protein] a 4-hydroxy-3- acyl-carrier protein acyl-sn-glycerol D-ala DAP-DAP stearate a peptide a peptide and incorporation I molybdopterin di-trans,octa-cisPSM7751_RS09915 thioredoxin- met [sulfur carrier] (2S)-4-acetamido- demethylmenaquinol-8 bifunctional NAD(P) PSM7751_RS01710 N 6 -lipoyl-L-lysine polyprenylbenzoate crosslink D-threo-isocitrate 6-hydroxynicotinate riboflavin oxaloacetate acetaldehyde dUTP cofactor) disulfide reductase: [+ 2 isozymes] PSM7751_RS14405 methionine 3-phosphate 2-aminobutanoate dimethylmenaquinone demethylmenaquinone -undecaprenyl transhydrogenase (S)-1-pyrroline- PSM7751_RS09370 adenosyltransferase: methyltransferase: an octanoyl-[acp] methyltransferase/2- diphosphate subunit beta: pntB 5-carboxylate L-ectoine synthase: lipoate biosynthesis PSM7751_RS16500 RS06535 RS08855 PSM7751_RS00825 methoxy-6-polyprenyl-1,4- undecaprenyl- glycine cleavage UDP-α-D- PSM7751_RS16065 and incorporation II glutathione biosynthesis lipoate-protein ligase 1-cis- a [protein] N-terminal- D-firefly 3-oxochol-4- (indol-3-yl) diphosphatase: lipoate salvage I SAM a sulfurated 1-myristoylglycerol a cis- FMNH NADP + H O 4-methylcatechol chloramphenicol MeOH bifunctional B: PSM7751_RS07245 benzoquinol methylase: a [glycine- SAM dethiobiotin a palmitoleoyl-[acp] vaccenoylglycerol- 2 2 glucuronate a [lipoyl-carrier menaquinol-9 biosynthesis PSM7751_RS17800 a reduced menaquinol-6 biosynthesis [sulfur carrier] 3-phosphate vaccenoyl-[acp] formyl-L-methionine luciferyl-CoA en-24-oyl-CoA acetamide ectoine demethylmenaquinone octanoate 6 PSM7751_RS13915 + 3-phosphate peptide deformylase: flavin reductase: acyl-CoA thioesterase: UDP-glucuronate protein] N - di-trans,octa-cis thioredoxin NADP cleavage complex L-glutamate-5- biotin synthase BioB: catechol 2,3- amidase: chloramphenicol catalase/ 6 sterol carrier protein: 5-epimerase: methyltransferase/2- lipoate--protein ligase: cys Glu octanoyl-L-lysine (R)-lipoate geranyl diphosphate H protein] N - glycine PSM7751_RS15250 PSM7751_RS09175 PSM7751_RS20960 dioxygenase: PSM7751_RS15765 acetyltransferase: demethylmenaquinol-9 menaquinol-7 -undecaprenyl demethylmenaquinol-6 semialdehyde PSM7751_RS06030 peroxidase HPI: methoxy-6-polyprenyl-1,4- glutamate-- lipoate--protein ligase: biosynthesis dehydrogenase 1-myristoyl-2- 1,2-dicis- [+ 2 isozymes] [+ 4 isozymes] [+ 2 isozymes] PSM7751_RS17465 PSM7751_RS20550 a [lipoyl-carrierPSM7751_RS17920 lipoyl synthase: phosphate lipoyl-L-lysine an unsulfurated PSM7751_RS14090 [+ 3 isozymes] PSM7751_RS06360 PSM7751_RS00955 β RS05845 cysteine ligase: bifunctional bifunctional met 5'-deoxyadenosine biotin acyl-carrier protein palmitoleoyl acyl-carrier protein vaccenoyl- an N-terminal L- + UDP- -L- RS03175 benzoquinol methylase: 6 PSM7751_RS17920 (aminomethyl- bifunctional proline formate H NADPH FMN D-firefly luciferin 3,24-dioxocholest- protein] N - PSM7751_RS03930 [sulfur carrier] methionyl-[protein] 2-hydroxy-5-methyl-6- chloramphenicol iduronate PSM7751_RS02640 demethylmenaquinone demethylmenaquinone IPP gcv system: transferring): dehydrogenase/L- SAH phosphatidate phosphatidate (indol-3-yl)acetate formaldehyde PSM7751_RS13915 octanoyl-L-lysine γ-L-glutamyl- a [lipoyl-carrier lipoyl-adenylate oxohexa-2,4-dienoate 4-en-26-oyl-CoA 3-acetate menaquinol-8 methyltransferase/2- methyltransferase/2- farnesyl-diphosphate PSM7751_RS17055 PSM7751_RS17055 glutamate gamma- L-cysteine protein]-N 6 - lipoyl synthase: methoxy-6-polyprenyl-1,4- lipoate--protein ligase: methoxy-6-polyprenyl-1,4- synthase: [+ 2 isozymes] semialdehyde adenosylhomocysteinase: glutathione synthase: lipoyl-L-lysine PSM7751_RS03930 benzoquinol methylase: PSM7751_RS17920 benzoquinol methylase: PSM7751_RS17960 dehydrogenase: PSM7751_RS14390 1-cis- a [protein]- an organic D-erythrose D-xylulose 2-chloro-trans cytidine PSM7751_RS08415 geranyl a [glycine- a [protein]-L-glutamine serotonin an acyl-CoA H O 2-deoxygluconate urea phenylglyoxylate methylglyoxal a [lipoyl-carrier PSM7751_RS13915 a [lipoyl-carrier PSM7751_RS13915 a [glycine-cleavage PSM7751_RS14405 SAM an octanoyl-[acp] a palmitoleoyl-[acp] vaccenoylglycerol- L-cysteine hydroperoxide 4-phosphate 5-phosphate 2 -dienelactone RS10955 RS13795 6 diphosphate cleavage complex transglutaminase: peroxiredoxin: acyl-CoA thioesterase: protein]-N - menaquinol-9 protein]-N 6 - menaquinol-6 complex H protein] N 6 - L-homocysteine 3-phosphate transketolase: dienelactone 2-deoxy-D-gluconate benzoylformate glyoxalase: cytidine deaminase: glutathione H protein] N 6 - autoinducer synthase: urea amidolyase: lipoyl-L-lysine lipoyl-L-lysine aminomethyldihydrolipoyl- Glu PSM7751_RS04810 PSM7751_RS14690 PSM7751_RS05050 PSM7751_RS20960 hydrolase: 3-dehydrogenase: decarboxylase: PSM7751_RS15070 PSM7751_RS01690 dihydrolipoyl- PSM7751_RS05720 PSM7751_RS01895 L-lysine L-serine degradation 1-cis-vaccenoyl- [+ 2 isozymes] [+ 2 isozymes] [+ 2 isozymes] [+ 2 isozymes] PSM7751_RS10110 PSM7751_RS13080 PSM7751_RS18570 [+ 4 isozymes] L-lysine VAI-1-2 S-methyl-5'- a [protein] N 6 -[(5-hydroxy-1H an intra- D-glyceraldehyde uridine acyl-carrier protein acyl-carrier protein 2-palmitoleoyl an alcohol F6P a carboxylate 3-dehydro-2- thioadenosine phosphatidate -indol-3-yl)ethyl]-L-glutamine protein disulfide 3-phosphate 2-chloromaleylacetate urea-1-carboxylate benzaldehyde (R)-lactate ser deoxy-D-gluconate RS11730 RS01430 aminomethyltransferase: L-serine L-aspartate L-glutamine PSM7751_RS17055 degradation I ammonia-lyase: an (S)-2- S-(2-hydroxyacyl) 3-hydroxy-5- 2-chloro-cis- (R)-3- degradation I 1-palmitoylglycerol acetate lauroyl-CoA H O 2-phosphoglycolate cis-dienelactone pyrazinamide 2-aminoprop-PSM7751_RS07595 SAM a butanoyl-[acp] a palmitoleoyl-[acp] halocarboxylate glutathione oxohexanoyl-CoA 2 dienelactone hydroxybutanoate 3-phosphate HAD family hydrolase: hydroxyacylglutathione acetate CoA- acyl-CoA thioesterase 2-enoate autoinducer synthase: dienelactone phosphoglycolate 3-hydroxybutyrate dienelactone amidase: gln PSM7751_RS20830 hydrolase: transferase: asp II: PSM7751_RS07225 hydrolase: phosphatase: dehydrogenase: hydrolase: PSM7751_RS15765 RS04100 imidazole glycerol PSM7751_RS05720 RS07575 L-glutamate aspartate 1-palmitoyl-2- [+ 5 isozymes] PSM7751_RS09750 PSM7751_RS06215 [+ 2 isozymes] [+ 3 isozymes] phosphate synthase S-methyl-5'- an (R)-2- 3-hydroxy-5- PSM7751_RS10110 PSM7751_RS18825 PSM7751_RS19735 PSM7751_RS10110 degradation I aminotransferase: PAI-1-2 acyl-carrier protein acyl-carrier protein palmitoleoyl a halide anion a 2-hydroxy glutathione acetyl-CoA laurate subunit HisH: thioadenosine hydroxyacid oxohexanoate pyrazine-2- PSM7751_RS15760 phosphatidate carboxylate 2-chloromaleylacetate glycolate acetoacetate 2-maleylacetate PSM7751_RS06410 2-iminopropanoate carboxylate aspartate Glu [+ 4 isozymes] glutamate aminotransferase: Glu a 3- Kdo - 4-methyl-3- an O-acetyl- 7,8-dihydro- RS00505 RS08520 dehydrogenase: PSM7751_RS08285 2 glutathione glycyl-glycine 5-hydroxyferulate coenzyme A succinyl-CoA uroporphyrinogen-I a DNA segment 7,8-dihydropterin hydroxyquinol SAM oxododecanoyl- a myristoyl-[acp] (palmitoleoyl) ADP-ribose PSM7751_RS00665 oxaloacetate oxoadipate O-acetyl-ADP- 8-oxoguanine [acp] -lipid IV gamma- 4-coumarate- 3-oxoadipate 2-oxoglutarate pyruvate autoinducer synthase: myristoyl transferase:A uroporphyrinogen recombinase: hydroxyquinol 8-oxoguanine glutamyltransferase: -CoA ligase: CoA-transferase: ribose deacetylase: guanine deaminase: PSM7751_RS05720 PSM7751_RS00935 decarboxylase: PSM7751_RS21170 1,2-dioxygenase: deaminase: PSM7751_RS15730 PSM7751_RS14935 PSM7751_RS14420 PSM7751_RS11760 PSM7751_RS17025 (Kdo) -lipid PSM7751_RS12495 [+ 4 isozymes] PSM7751_RS04675 PSM7751_RS17000 S-methyl-5'- 2 γ-L-glutamyl- 5-hydroxy- 4-methyl-3- L-phenylalanine degradation I (aerobic) PAI-1 acyl-carrier protein acyl-carrier protein L-cysteinyl-glycine succinate acetate ADP-D-ribose a DNA segment in 7,8- thioadenosine A, cold adapted glycylglycine feruloyl-CoA oxoadipyl-CoA coproporphyrinogen I 2-maleylacetate urate RS11665 RS09900 L-glutamate reverse orientation dihydrolumazine degradation X (6R)-4a-hydroxy- tetrahydrobiopterin 4a-hydroxytetrahydrobiopterin dehydratase: 1-stearoyl- salicyl-6-hydroxy-2- β-D-fructofuranose an organic (2S)- Glu a 3-oxooctanoyl- chitin FMNH NAD + a uridine in tRNA hydroxyquinol cobyrinate PSM7751_RS14670 SAM an oleoyl-[acp] sn-glycerol cyclohexene-on-oyl 1-phosphate 2 glutamate [acp] hydroperoxide ethylmalonyl-CoA met RS08595 met 3-phosphate carboxylesterase: fructose bisphosphate beta-N- flavin reductase: RS02775 dehydrogenase: autoinducer synthase: tRNA dihydrouridine alkylhydroperoxidase: methylmalonyl- hydroxyquinol cobyrinic acid a,c- PSM7751_RS04980 aldolase: acetylhexosaminidase: PSM7751_RS09175 PSM7751_RS00665 PSM7751_RS05720 6-hydroxy-2- synthase DusB: PSM7751_RS14725 CoA epimerase: 1,2-dioxygenase: diamide synthase: (6R)-L-erythro-5,6,7,8- L-erythro-7,8- 1-stearoyl-2- PSM7751_RS05260 PSM7751_RS10230 [+ 4 isozymes] 2-oxoglutarate S-methyl-5'- salicyl alcohol cyclohexen- N-acetyl-D- PSM7751_RS03970 [+ 3 isozymes] PSM7751_RS09630 PSM7751_RS04675 PSM7751_RS02190 acyl-carrier protein + tetrahydrobiopterin dihydrobiopterin AAI-1 acyl-carrier protein oleoyl-sn-glycerol D-glyceraldehyde DHAP chitin H NADH FMN a 5,6-dihydrouridine (2R)- cob(II)yrinate thioadenosine one-carboxylate glucosamine an alcohol 2-maleylacetate 3-phosphate in tRNA ethylmalonyl-CoA a,c-diamide RS05825

RS04740 3E,5Z- RNase R degradation a 2,3,4-saturated (S)-4- (2R,3S)-3- phosphoenol a 3-oxohexanoyl- acetate hydrogencarbonate H + oleoyl-CoA H O 4-hydroxybenzoate oxaloacetate SAM tetradecadienoyl-CoA 2 [acp] substrate RNA fatty acyl CoA hydroxymandelate isopropylmalate pyruvate acyl-CoA thioesterase: ribonuclease R: acetate CoA- acyl-CoA thioesterase Carbohydrate Degradation autoinducer synthase: carbonic anhydrase: 4-hydroxybenzoate phosphoenolpyruvate 3-isopropylmalate PSM7751_RS20960 PSM7751_RS15440 transferase: II: PSM7751_RS07225 mandelate racemase: pyruvate kinase: PSM7751_RS05720 PSM7751_RS14850 3-monooxygenase: carboxykinase (ATP) dehydrogenase: [+ 2 isozymes] a nucleoside 5'- PSM7751_RS06215 [+ 2 isozymes] PSM7751_RS04680 PSM7751_RS12785 S-methyl-5'- a diribonucleotide H O CO PSM7751_RS16440 : PSM7751_RS16855 PSM7751_RS12390 RS18065 ethene and chloroethene degradation VAI-1 (3E,5Z)- a 2,3,4-saturated 2 2 heparin degradation acyl-carrier protein coenzyme A monophosphate acetyl-CoA oleate (R)-4- phosphoenol 4-methyl-2- thioadenosine tetradecadienoate fatty acid protocatechuate pyruvate propene degradation hydroxymandelate pyruvate oxopentanoate ethene chloroethene heparin heparinase: propene a DNA containing a (3R)-3- icosapentaenoyl- a [DNA]-3'- a 5'-phospho- methyl (indol- a monocarboxylic a 2,3,4-saturated PSM7751_RS15595 an apurinic/ a phenol an aryl sulfate 3-mercaptopyruvate (S)-mandelate ferroheme o RS03055 4-deoxy-2-O-sulfo- SAM hydroxybutanoyl- CoA hydroxyl [DNA] 3-yl)acetate acid amide CTP 1,2-diacyl-sn β acyl-CoA thioesterase: apyrimidinic site replication- carboxylesterase: aryl-sulfate -L-erythro-hex-4- [acp]autoinducer synthase: endonuclease III: 3-mercaptopyruvate amidase: -glycerol 3- ethylene oxide chlorooxirane PSM7751_RS20960 associated protein A: PSM7751_RS04980 sulfotransferase: mandelate racemase: heme A synthase: enopyranuronosyl-(1,4)-D-N PSM7751_RS05720 PSM7751_RS18155 sulfurtransferase: PSM7751_RS15765 phosphate PSM7751_RS21125 PSM7751_RS03780 PSM7751_RS04680 PSM7751_RS19530 -sulfoglucosamine 6-O-sulfate (R)-1,2- (S)-1,2- [+ 2 isozymes] a 3'-terminal a 5'-phospho- MeOH (indol-3-yl)acetate PSM7751_RS15080 [+ 3 isozymes] a CDP-2,3,4- epoxyalkane- epoxyalkane- HAI-1 S-methyl-5'- acyl-carrier protein epoxypropane epoxypropane coenzyme A icosapentaenoate unsaturated sugar [DNA] [DNA] a phenol an aryl sulfate saturated- -coenzyme M -coenzyme M thioadenosine pyruvate a monocarboxylate (R)-mandelate ferroheme a diacylglycerol RS17620 transferase: transferase: epoxyalkane- epoxyalkane- β PSM7751_RS03880 PSM7751_RS03880 4-deoxy- -L-erythro-hex-4- -coenzyme M -coenzyme M enopyranuronosyl-(1,4)-D-N transferase: transferase: 2-hydroxyethyl- 2-chloro-2- all-trans- a peptide with 3-[(4'-methylthio) -sulfoglucosamine 6-O-sulfate coenzyme M a ribonucleic acid O-ureido-L- 2-deoxy-D-ribose cobalt- PSM7751_RS03880 PSM7751_RS03880 DL-allothreonine 1,2-epoxypropane a tripeptide pentanoyl-CoA acetate asp an N-terminal CoM hydroxyethyl-CoM 2-(R)- 2-(S)- retinyl palmitate homoserine butyl]malate precorrin-6A epoxyalkane--coenzyme ribonuclease PH: peptidase T: carboxylesterase: acetate CoA- L-alanine hydroxypropyl- hydroxypropyl- serine argininosuccinate aminopeptidase N: 3-isopropylmalate cobalt-precorrin- M transferase: PSM7751_RS17410 PSM7751_RS11470 transferase: ribokinase: CoM PSM7751_RS04980 synthase: dehydrogenase: 6A reductase: RS03040 CoM hydroxymethyltransferase: glyA PSM7751_RS03880 a nucleoside PSM7751_RS06215 PSM7751_RS11900 PSM7751_RS17435 a ribonucleic acid a proteinogenic palmitate all-trans-retinol PSM7751_RS17470 PSM7751_RS12390 PSM7751_RS02170 N,6-O-disulfo-D-glucosamine gly acetaldehyde diphosphate a dipeptide a peptide ala 2-hydroxypropyl-CoM amino acid acetyl-CoA pentanoate canavaninosuccinate 7-(methylthio)-2- 2-deoxy-D-ribose cobalt- 2-oxoethyl-CoM oxoheptanoate 5-phosphate precorrin-6B

2-oxopropyl-CoM RS02035 N-sulfo-D-glucosamine a 2,3,4-saturated a 2,3,4-saturated 2- (R)-1- a [lipoyl-carrier lysine within 3-[(3'-methylthio) α-D-ribofuranose D-ribulose adenosylcobyrate (R)-lipoate (R)-lipoate a carboxylic ester canavaninosuccinate a protein agmatine 2-carboxyethyl- fatty acyl-[acp] lysophosphatidate aminopropan-2-ol protein]-L-lysine gcv protein H propyl]malate 5-phosphate adenosylcobinamide- lipoate--protein ligase: lipoate--protein ligase: carboxylesterase: argininosuccinate agmatinase: ribulose-phosphate CoM trypsin: 3-isopropylmalate ribokinase: phosphate synthase: PSM7751_RS17920 PSM7751_RS17920 PSM7751_RS04980 lyase: PSM7751_RS19900 3-epimerase: a [glycine-cleavage PSM7751_RS15490 dehydrogenase: PSM7751_RS17435 acetoacetate a 2,3,4-saturated PSM7751_RS16790 a [lipoyl-carrier protein]- PSM7751_RS08760 [+ 2 isozymes] chitin degradation II (Vibrio) complex H protein] a carboxylate an alcohol PSM7751_RS12390 PSM7751_RS14920 acyl-carrier protein 1,2-diacyl-sn- N 6 -lipoyl-L-lysine a peptide a peptide α D-glucosamine adenosylcobinamide 6 fumarate L-canavanine putrescine urea -D-ribose D-xylulose RS05820 N -lipoyl-L-lysine 6-(methylthio)- glycerol 3-phosphate 5-phosphate malonate chitin 2-oxohexanoate 5-phosphate

5-amino-4- 3α,7α,12α-trihydroxy-24- 3-[(5'-methylthio) D-ribose 5- PRPP F6P maltohexaose (3S)-citryl-CoA butanoyl-CoA acetate sec maltose D-galactose degradation II imidazolecarboxyamide oxo-5-β-cholestanoyl CoA a protein a tRNA ser pentyl]malate phosphate a chitodextrin adenine fructose-6- alpha-glucosidase: acetate CoA- RS12965 sterol carrier protein: citryl-CoA lyase: endopeptidase La: serine--tRNA ligase: 3-isopropylmalate ribose 5-phosphate L-arabinose degradation I phosphoribosyltransferase: phosphate aldolase: PSM7751_RS18795 transferase: alpha-glucosidase: D-galactopyranose PSM7751_RS17465 PSM7751_RS01350 PSM7751_RS11220 dehydrogenase: isomerase A: PSM7751_RS08115 PSM7751_RS06215 PSM7751_RS05870 PSM7751_RS18795 D-galactose 1- PSM7751_RS07790 D-glucopyranose maltopentaose propanoyl-CoA choloyl-CoA oxaloacetate PSM7751_RS12390 PSM7751_RS02110 D-glyceraldehyde acetyl-CoA an L-seryl- L-arabinopyranose dehydrogenase: AICAR dihydroxyacetone acetyl-CoA butanoate a peptide a peptide sec D-ribulose 3-phosphate [tRNA ] 8-(methylthio)- D-glucopyranose PSM7751_RS18535 5-phosphate D-galactono- a chitodextrin 2-oxooctanoate L-ribulose 1,4-lactone a dimer of non-adjacent 2'- D-sedoheptulose D-glyceraldehyde an all-trans an (L-cysteinylglycine) 3-[(6'-methylthio) α-L- ribulokinase: maltopentaose benzylbenzoate N-acetylputrescine methylsalicylate ribulose D-mannose degradation deoxycytidine and thymidine in DNA 7-phosphate 3-phosphate -retinyl ester -S-conjugate hexyl]malate rhamnopyranose PSM7751_RS04510 alpha-glucosidase: deoxyribodipyrimidine transketolase: carboxylesterase: carboxylesterase: aminopeptidase N: acetylpolyamine carboxylesterase: 3-isopropylmalate L-rhamnose D-galactonate beta-N- photolyase: PSM7751_RS18795 amidohydrolase: ribulokinase: L-ribulose 5- D-mannopyranose PSM7751_RS05050 PSM7751_RS04980 PSM7751_RS04980 PSM7751_RS11900 PSM7751_RS04980 dehydrogenase: mutarotase: acetylhexosaminidase: PSM7751_RS04105 PSM7751_RS06760 PSM7751_RS04510 phosphate 6-phosphate [+ 2 isozymes] D-glucopyranose maltotetraose a fatty acid all-trans-retinol benzyl alcohol benzoate an L-cysteine- MeOH salicylate PSM7751_RS12390 PSM7751_RS02050 mannose-1-phosphate N,N'- PSM7751_RS10230 N,N',N''- D-xylulose D-ribose 5- gly β-L- a thymine in DNA a cytosine in DNA S-conjugate acetate putrescine 9-(methylthio)- L(or D)-ribulose guanylyltransferase/ diacetylchitobiose triacetylchitotriose 5-phosphate phosphate rhamnopyranose 2-oxononanoate 5-phosphate mannose-6- beta-N- D-xylulose phosphate isomerase: acetylhexosaminidase: α α 5-phosphate PSM7751_RS20565 PSM7751_RS10230 RNase III mRNA 3 ,7 -dihydroxy- a (1->4)- (-)-methyl all-trans- 6,7-dimethyl-8-(1- β maltoheptaose α maltotriose a phenyl acetate carbonic acid a kanamycin F6P N-acetyl-D- processing substrate 24-oxo-5 - -D-glucan jasmonate retinyl palmitate D-ribityl)lumazine cholestanoyl CoA alpha-glucosidase: alpha-glucosidase: alpha-glucosidase: carboxylesterase: carboxylesterase: riboflavin synthase: aminoglycoside glucosamine ribonuclease III: sterol carrier protein: arylesterase: carbonic anhydrase: PSM7751_RS18795 PSM7751_RS18795 PSM7751_RS18795 PSM7751_RS04980 PSM7751_RS04980 PSM7751_RS00070 phosphotransferase: PSM7751_RS15170 PSM7751_RS17465 a (1->4)- PSM7751_RS17070 PSM7751_RS14850 RNase III processing an mRNA fragment chenodeoxycholoyl- D-glucopyranose maltohexaose D-glucopyranose α D-glucopyranose maltose MeOH (-)-jasmonate palmitate a retinol acetate a phenol riboflavin ARP CO H O PSM7751_RS17260 propanoyl-CoA -D-glucan 2 2 product mRNA CoA a kanamycin 3'-phosphate a branched- chain sn-glycerol a polar spermidine spermidine spermidine spermidine amino acid 3-phosphate a C4- amino acid putrescine putrescine 3+ 3+ 3+ putrescine putrescine 3+ a polyamine molybdate Fe Fe Fe Fe a Coα-[α-(5,6- dicarboxylate phosphonate a branched- a branched- a branched- thiamine spermidine spermidine spermidine Ni 2+ enterobactin lactose 6'- a polar sn-glycerol sn-glycerol 3,5- D-fructose a 2,3,4-saturated fatty acyl CoA a 2,3,4-saturated fatty acyl CoA a 2,3,4-saturated fatty acyl CoA a 2,3,4-saturated fatty acyl CoA a 2,3,4-saturated fatty acyl CoA a 2,3,4-saturated fatty acyl CoA a 2,3,4-saturated fatty acyl CoA α spermidine spermidine spermidine spermidine putrescine dimethylbenzimidazolyl) chromate a tricarboxylate a tricarboxylate a tricarboxylate phosphonate phosphonate chain chain chain enterobactin a lipopolysaccharide malonate a polyamine a polyamine a polyamine a polyamine a nucleotide a sulfonate a dipeptide -L- diphosphate putrescine an oligopeptide 2+ amino acid 3-phosphate 3-phosphate dimethoxytoluene cis-vaccenoyl-CoA cis-vaccenoyl-CoA cis-vaccenoyl-CoA cis-vaccenoyl-CoA cis-vaccenoyl-CoA putrescine putrescine putrescine putrescine putrescine putrescine Fe ]-cobamide phosphate predicted amino acid amino acid amino acid 1-phosphate cis-vaccenoyl-CoA cis-vaccenoyl-CoA rhamnopyranose a lipopolysaccharide a lipopolysaccharide predicted predicted predicted predicted predicted predicted ABC predicted ABC ABC predicted predicted ABC ABC ABC ABC ABC predicted ABC transporter predicted ABC transporter transporter ABC ABC RS18040 transporter transporter RS03050 RS15285 RS10960 RS01095 RS00785 RS03590 transporter transporter RS11580 RS17885 RS01450 RS03705 RS02770 RS03810 RS17700 RS04725 RS03405 RS03400 RS06225 transporter RS04225 transporter of RS05540 of a RS03025 RS02540 RS03030 RS02380 RS17715 RS17710 efflux transporter of RS09275 RS08930 RS08925 RS20130 RS17895 RS12955 RS20270 RS04400 RS16880 RS17420 RS00515 RS05605 RS02115 RS14960 RS14945 RS06485 RS00960 RS14560 RS15795 RS02030 of a C4- of sn- transporter transporter of spermidine/ of spermidine/ of spermidine/ of spermidine/ of a polar phosphonate branched- a lipopolysaccharide dicarboxylate glycerol 3- of a polyamine of molybdate putrescine putrescine 3+ 3+ 3+ putrescine putrescine 3+ amino acid chain α Fe Fe spermidine spermidine Fe spermidine Fe Ni 2+ enterobactin a Coα-[α-(5,6- a branched- a branched- a branched- phosphate 3,5- a 2,3,4-saturated fatty acid a 2,3,4-saturated fatty acid a 2,3,4-saturated fatty acid a 2,3,4-saturated fatty acid a 2,3,4-saturated fatty acid a 2,3,4-saturated fatty acid a 2,3,4-saturated fatty acid -L- thiamine putrescine chromate lactose a tricarboxylate a tricarboxylate a tricarboxylate a polar phosphonate phosphonate amino acid enterobactin malonate sn-glycerol sn-glycerol a polyamine a polyamine a polyamine a polyamine D-fructose a nucleotide a sulfonate a dipeptide 2+ chain rhamnopyranose diphosphate spermidine spermidine putrescine putrescine spermidine putrescine spermidine an oligopeptide Fe dimethylbenzimidazolyl) chain chain a lipopolysaccharide a lipopolysaccharide 3-phosphate 3-phosphate dimethoxytoluene cis-vaccenate cis-vaccenate cis-vaccenate cis-vaccenate cis-vaccenate cis-vaccenate cis-vaccenate a C4- amino acid phosphonate putrescine putrescine putrescine putrescine ]-cobamide amino acid amino acid amino acid a polyamine molybdate spermidine spermidine spermidine spermidine a polar a lipopolysaccharide dicarboxylate a branched- sn-glycerol putrescine putrescine putrescine putrescine amino acid chain 3-phosphate amino acid This diagram was automatically generated by SRI International Pathway Tools version 25.0, authors S. Paley and P.D. Karp.