Keyword Index

[11C]-( + )-PHNO ...... S384, S402 Addiction ...... S1, S6, S7, S9, S11, S13, S14, S17, S19, 17b-estradiol ...... S199, S200 S21, S28, S35, S47, S50, S78, S81, S132, S164, S166, S175, S189–S193, S196, S197, S211, S216, S235, S239, S261, S265, S277, S280, S283, S286, S288, 2-AG ...... S295, S442 S289, S301, S308, S311, S319–S321, S323–S327, S329, S331–S334, S336, S338, 5-HT ...... S19, S51, S59, S60, S62, S76, S77, S85–S86, S342, S367, S372–S380, S384, S396, S402–S405, S428, S431, S439–S441, S129, S136, S183, S184, S210, S224, S225, S265, S282, S297, S304, S307, S310, S446 S329, S429, S430, S433, S437 Addiction liability ...... S311 5-HT1B ...... S79, S224, S225, S331 Adenosine ...... S322, S338, S375 5-HT7 ...... S224, S225, S430–S436 Adenylyl cyclase ...... S311, S333 5-HTP ...... S77, S206, S297 ADHD ...... S5, S10, S36, S55, 5-HT2A receptor ...... S181, S282, S335 S66, S69, S80, S84, S112, S126, S136, S149–S156, S163, S187, S199, S230, 5HT2C receptor ...... S306 S237, S238, S249, S250, S252, S255, S260, S265, S290, S310, S398, S420, 5-HTP ...... S77, S206, S297 S446, S448 A-85380 ...... S179, S402 Adherence ...... S65, S105, S167, S305, S422 A2 ...... S111 Adjunctive treatment ...... S100, S108, S303, S346, S356, S359, S416 Adolescence ...... S5, S6, S11, S18, S21, S32, S49, S50, S60, S68, S83, S111, S136, S141, S145, S147, S148, S214, S215, S238, S240, S256, A S273, S275, S283, S312, S316, S333, S336, S367, S377, S380, S389, S406, S409, S431, S442 Adolescent ...... S5, S11, S15, S18, S21, S32, S50, S51, S69, Abeta ...... S44, S91 S76, S77, S83, S84, S101, S135, S137, S145, S151, S160, S238, S243, S258, S273, Abstinence ...... S50, S165, S178, S179, S190, S192, S235, S274, S296, S297, S307, S313, S316, S326, S342, S348, S366, S367, S370, S389, S236, S243, S282, S285, S291, S311, S328, S331, S368, S378, S380, S402, S404, S390, S394, S398, S419, S431, S448 S427 Adolescent depression ...... S389, S390, S412 Abuse ...... S6, S14, S19, S35, S47–S50, S81, S87, S118, Adolescent-onset ...... S275, S367, S390 S127, S145, S148, S149, S159, S167, S179, S189, S190, S195, S196, S216, S217, Adrenergic beta-2 receptors ...... S124, S125 S230, S243, S262, S263, S284, S285, S289, S291, S301, S316, S322, S326, S330, S342, S365, S367, S369–S372, S375, S377, S379, S397, S404, S426, S440, S441 Adult neurogenesis ...... S89 Abuse potential ...... S192, S217, S429 Advanced paternal age ...... S102, S250 Acamprosate ...... S114, S381, S382 Adverse effects ...... S65, S101, S120, S169, S170, S175, S228, S229, S231, S235, S273, S299, S359, S418, S421 ACC ...... S27, S28, S36, S53, S110, S112, S114, S118, S119, S125, S134, S135, S140, S141, S156, S157, S163, S165, S221, Affect regulation ...... S109, S289 S238, S269, S272, S276, S285, S286, S312, S314, S321, S345, S361, S381, S382, Affective disorders ...... S7, S18, S56, S77, S386, S387, S388–S391 S85, S113, S126, S129, S144, S161, S172, S221, S252, S264, S368, S399, S410, Accumbens ...... S50, S72, S145, S164, S165, S183, S265, S333, S393 S442, S448 Accumbens shell ...... S334 Affective symptoms ...... S69, S294, S331, S409 ACE inhibitor ...... S179 African American ...... S97, S105, S305, S406, S424 Acetylcholine receptors ...... S96, S179, S180, S184, S326, Afro-trinidadians ...... S177 S367, S372, S373, S379, S402 Age ...... S1, S3–S6, S10, S20, S23, S26, S27, S32, S34, Acetyl-L-carnitine ...... S345 S42, S43, S47, S49, S50, S52, S58, S63, S67–S71, S84, S87, S89, S92, S93, S96, S97, S102, S105, S106, S109, S112, S117, S120, S123–S130, S135, S138, Acoustic startle ...... S54, S77, S78, S133, S183, S240, S242, S448 S140, S141, S145–S149, S152–S156, S158–S161, S163, S164, S166–S169, ACTH ...... S324, S378 S171, S172, S174, S176, S177, S180, S196, S200, S213, S219–S221, S224, Actin ...... S255, S260, S336, S339 S226–S229, S232, S236, S238–S241, S243, S244, S246, S249–S253, S255– Acute ...... S1, S4, S5, S7, S14, S16–S18, S20, S257, S259, S261, S262, S264–S268, S271, S272, S275–S280, S282, S285, S24, S38, S44, S49, S56, S60, S67, S81, S82, S84, S88, S95, S96, S98, S101, S288, S290, S292, S296, S298, S301, S302, S306, S307, S313–S315, S318, S125–S127, S136, S146, S158, S168, S170, S172, S176–S178, S182, S188, S191, S326, S327, S336, S337, S347–S349, S355, S357, S362, S366, S367, S369, S371, S192, S195, S196, S203–S205, S208, S212, S215, S216, S222, S229, S236, S238, S377, S381–S386, S388–S392, S394–S403, S407–S411, S413, S419, S422, S423, S262, S268, S276, S278, S285, S287, S289, S295, S305, S306, S311, S312, S314, S426, S439, S448 S317, S320, S322, S325, S329, S331, S332, S338, S341, S343, S346–S349, S352, Aggression ...... S60, S78, S81, S82, S120, S136, S136, S139, S354, S359, S366, S367, S372, S377, S378, S381, S383, S395, S403–S405, S410, S152, S153, S160, S223, S227, S228, S262, S324, S345, S375, S392 S411, S427, S430, S436, S445–S447 Aging ...... S3, S4, S26, S43, S63, S75, S92, S236, S254, Acute exacerbation of schizophrenia ...... S98, S106 S255, S275, S335, S398 Acute trauma ...... S268 Agitation ...... S227, S419, S441

ACNP 50th Annual Meeting Keyword index S484 Agonist ...... S3, S14, S19, S34, S36, S47, S50, S54, S55, S72, Amyloid imaging ...... S154 S76, S79, S97, S99, S106, S107, S126, S133, S169, S171, S178, S181–S184, S190, Anabolic-androgenic steroids ...... S369 S192, S193, S195, S211, S214, S224, S225, S228, S237, S268, S286, S304, Analysis ...... S4, S5, S11, S15, S17, S19–S22, S26, S307–S310, S312, S328, S331, S333, S340, S342, S375, S402, S428, S432, S28, S29, S31, S36, S45, S46, S48, S51, S52, S54, S55, S57, S58, S60, S61, S64, S437–S439, S441, S442 S65, S68, S70, S77–S81, S84, S85, S88, S89, S91, S93, S95–S100, S102–S105, Akt ...... S9, S21, S56, S90, S202, S203 S107–S110, S112, S113, S116, S117, S120, S122, S126, S130, S132–S136, AKT1 ...... S22, S49, S320 S140–S149, S152–S157, S160, S162–S165, S169, S171, S173, S174, S176, S179, Alcohol ...... S5, S7, S12, S52, S79–S81, S99, S105, S114, S181, S182, S187, S192, S194, S196, S198, S199, S202–S204, S207, S208, S143, S151, S164, S166, S177, S178, S181, S188, S191–S196, S259, S283–S291, S211–S214, S217–S219, S221–S224, S226, S227, S229, S232, S235, S239–S241, S295, S301, S306, S322, S323, S325, S326, S329, S338, S341, S366, S368, S369, S244, S245, S248, S250, S254–S257, S259–S262, S264, S266–S268, S271, S274, S371–S374, S378–S382, S404, S405, S423, S428–S430, S439 S276, S277, S279, S280, S283, S285, S288–S291, S293, S295–S298, S300–S303, S305, S306, S309, S311, S312, S314, S319, S327, S329, S334–S336, S340–S342, Alcohol abuse ...... S52, S65, S154, S193, S324, S326, S344, S346, S347, S352–S354, S356–S363, S365, S368, S369, S372–S376, S341, S365, S372, S422, S428 S378–S381, S383–S391, S393–S399, S401–S405, S408–S410, S413, S414, Alcohol addiction ...... S166 S416–S423, S425, S426, S428, S429, S434, S437, S437, S445, S448 Alcohol challenge ...... S177 Anandamide ...... S295, S383 Alcohol dependence ...... S7, S12, S52, S114, S193, S195, Ancestry ...... S46, S65, S132, S177, S259, S262, S235, S285, S288, S301, S329, S371, S372, S374, S425, S428 S374, S376, S378, S397, S423, S424 Alcohol drinking ...... S79, S80, S164, S180, S191, S194, S428 Anhedonia ...... S28, S38, S41, S125, S178, S200, S201, Alcohol withdrawal ...... S7, S285 S205, S213, S242, S391, S433 Alcoholic rats ...... S164 Animals ...... S8, S9, S14–S19, S22, S24, S25, S39, S43, S45, S50, S55, S56, S58, S60, S63, S66, S68, S75–S78, S81, S86, S88, S90, Alcoholism ...... S12, S79, S154, S164, S166, S177, S111, S114, S126, S146, S147, S149, S151, S158, S161, S164, S182–S184, S186, S180, S191, S192, S283, S288, S301, S324, S326, S329, S338, S341, S342, S369, S188–S191, S193, S196, S197, S199–S208, S211–S213, S215–S217, S222, S266, S372, S377, S403, S428, S429 S282, S305–S307, S309, S311–S313, S322, S325, S326, S332, S333, S337, S339, Algorithm ...... S65, S159, S268, S352, S381, S393, S398, S417, S428 S342, S351, S363, S366, S373, S390, S396, S397, S406, S409, S414, S415, Allopregnanolone ...... S81, S340 S430, S432, S433, S435, S439, S445, S447 Allosteric ...... S59, S181, S181, S186, S227, S236, S310, S382, S437, S438 Anorexia nervosa ...... S47, S48, S265, S266, S297 Allosteric modulator ...... S230, S310, S382, S437, S438 Anterior cingulate ...... S16, S20, S27, S36, S38, S49, S51, S53, S83, S109, S110, S115, S119, S126, S134–S136, S140–S142, S155–S157, Allosteric regulation ...... S181 S165, S194, S221, S256, S266, S268, S269, S271, S272, S274–S277, S279, S281, Alpha 3 subunit ...... S372 S283–S286, S288, S290, S302, S303, S312, S315, S319, S321, S322, S345, S362, Alpha 7 receptor agonist ...... S182 S364, S381, S382, S384, S386–S394, S396–S398, S416, S424, S448 Alpha-2 adrenergic ...... S331, S332 Antibodies ...... S4, S14, S31, S37, S63, S88, S184, Alpha-2 nicotinic receptors ...... S373 S242, S312, S340, S382 Alpha7 ...... S96, S98, S106, S182, S183, S209 Anticipation ...... S15, S52, S111, S115, S140, S145, S155, S210, S239, S242, S272, S273, S288, S347 Alpha-7 nachr ...... S184 Antidepressant ...... S3, S16, S38, S39, S45, Alpha7 neuronal nicotinic receptor ...... S98 S57, S62, S65, S82, S83, S86, S87, S89, S117, S119, S139, S146, S161, S172, Alpha-lipoic acid ...... S345 S200–S202, S204, S206, S224, S225, S231, S255, S263, S265, S295, S299, Alpha7 nicotinic receptor agonist ...... S185 S300, S302–S304, S311, S327, S343–S347, S351–S354, S356, S360, S386, Alzheimer’s ...... S3, S4, S17, S25, S43, S44, S51, S52, S63, S64, S394, S397, S402, S411–S413, S417, S419, S421–S424, S431, S432, S434, S435, S66, S92, S154, S172, S182, S184, S223, S227, S236, S254, S257, S269, S364 S443, S446 AM251...... S405 Antioxidants ...... S443 American Indian ...... S369, S377 Antipsychotic ...... S42, S64, S65, S83, S90, S95, S99, S100, S102–S107, S120, S121, S128, S132, S135, S167–S175, S182, S184, Amino acid neurotransmitter ...... S136, S204 S186, S187, S200, S208, S210, S211, S221, S228, S232, S246, S247, S249–S251, Amiodarone ...... S181, S182 S272, S274–S276, S291, S320, S334, S335, S349, S352, S356, S382–S384, S397, Amisulpride ...... S175, S272, S430 S424, S430, S435, S437, S438 AMPA ...... S16, S17, S38, S53, S62, S72, S186, S218, S227, S239, S336 Antipsychotic agents ...... S98, S102, S107, S120, S186, S437 AMPA PAM ...... S230 Antipsychotic drug ...... S65, S104, S135, S171, S186, S187, S210, S320, S335, S354, S382 AMPA receptor ...... S16, S17, S62, S72, S88, S186, S215, S218, S223, S227, S230, S336, S412 Antipsychotic response ...... S132 Amperometry ...... S430 Antipsychotic-naive ...... S120 Amphetamine ...... S9, S13, S15, S20, S48, S147, S195, Antisocial personality disorder ...... S385 S199, S212, S213, S287, S290, S311, S369, S375, S380, S426, S434, S437, S441 Anxiety ...... S2, S7, S18, S38, S47, S48, S54, S59, Amygdala ...... S1, S2, S13, S16–S18, S21, S22, S24, S60, S70, S73, S75, S76, S78, S80, S81, S83, S87, S90, S94, S101, S108–S111, S29, S33, S41, S49, S53, S54, S66–S69, S76, S78, S79, S82, S93, S94, S109–S112, S119, S122, S135, S136, S140, S141, S143, S144, S148, S160, S162, S163, S165, S116, S119, S126, S140, S142–S145, S148–S151, S158, S161, S163, S174, S204, S172, S179, S193, S204, S214, S224–S226, S229, S241, S249, S250, S252–S256, S214, S241, S242, S253, S265, S266, S268, S269, S277, S290, S295, S315, S317, S258, S265, S283, S287, S291, S296, S297, S301, S302, S304, S306, S307, S317, S319, S326, S329, S335, S337, S339–S341, S361, S362, S368, S386, S388, S393, S331, S335, S341, S343, S347, S351, S354, S359, S371, S372, S376, S389, S395, S394, S396, S399, S400, S402–S405, S412, S422, S432, S442 S405, S407, S421, S443, S446, S448

ACNP 50th Annual Meeting Keyword index S485 Anxiety disorders ...... S21, S23, S48, S49, S54, Anxiety ...... S2, S7, S15, S18, S21, S23, S24, S69, S70, S81, S83, S90, S109–S112, S120, S139, S141, S142, S146, S153, S162, S38, S47, S48, S49, S54, S59, S60, S69, S70, S73, S75, S76, S77, S78, S163, S224, S225, S249, S250, S253, S256, S263, S306, S307, S422, S426, S80, S81–S84, S88, S90, S92, S94, S102, S108, S109, S110–S112, S119, S442, S445 S120, S123, S125, S136–S137, S139–S144, S146, S148, S153, S160–S163, S166, Anxiety-like behavior ...... S76–S78, S80–S82, S252, S306, S327, S172–S173, S180, S194, S200, S202, S204, S207, S214, S224, S225, S226, S331, S341, S448 S229, S241–S242, S245, S249, S250, S252–S256, S258, S259, S263, S266, S270, S272, S283, S287–S288, S291, S296, S298, S301, S302, S304, Anxiolytic ...... S38, S77, S172, S177, S188, S306–S307, S317, S327, S330–S332, S335, S340–S341, S343, S347, S351, S200, S204, S304, S341, S352, S378, S405, S408, S421, S448 S354, S359, S371–S372, S376, S390, S392, S395, S405, S408, S421, S425, S433, APOE ...... S4, S14, S43, S63, S64, S254, S257, S261 S441–S442, S445–S448 APOE genotypes ...... S254 Axon initial segment ...... S219 APOE2 ...... S63, S64, S257 Appetitive ...... S1, S35, S203, S204, S403, S406 B ARC ...... S8, S239, S258

Aripiprazole ...... S105, S120, S174, S186, Baby cry ...... S118 S228, S235, S345, S346, S349–S351, S356, S394, S424 Baclofen ...... S34, S36, S47, S72, S290, S405, S428 Arthritis ...... S159, S447 BALB/cj ...... S76 Asenapine ...... S181, S352 Basal forebrain ...... S67, S93, S241 Asian American ...... S406 Basal ganglia ...... S84, S189, S199, S268, S271, S321, Asic1a ...... S82 S381, S392, S404, S417 ASL ...... S276, S394 Bath salts ...... S441 Association ...... S2, S3, S5, S8, S11, S17, S21–S24, BCG...... S88 S29, S38, S41, S43, S45, S47, S50–S52, S60–S62, S65, S66, S70, S77, S86, S93, S95, S102, S113, S115, S122, S124, S130–S137, S139, BDNF ...... S4, S18, S24, S35, S45, S54, S55, S57, S73, S143–S147, S152, S155, S158, S160, S161, S174, S176, S188, S198, S222, S200, S207, S208, S212, S213, S222, S253, S258, S328, S334, S341, S412, S413, S225–S228, S230, S237–S239, S242, S245, S246, S248, S250–S252, S434, S91–S93, S125, S127, S149, S150 S255–S260, S262, S263, S265, S277, S279, S283, S284, S291, S298, S301, Behavior ...... S2, S6, S9, S14, S15, S17–S19, S21, S23, S303, S305, S313, S315–S317, S323, S324, S337, S338, S343–S346, S355, S356, S24, S28, S31, S35, S40, S41, S43, S48–S50, S55, S57, S59, S60, S63, S67, S68, S361, S364, S366–S370, S373–S383, S389, S390, S392, S395, S401, S408, S70–S72, S74, S77–S80, S82, S83, S86, S88, S90, S92, S94, S96, S109, S114, S417, S423, S424, S429, S434, S448 S118, S120, S121, S123, S126, S127, S130, S135–S138, S145, S148, S152, S153, Association learning ...... S111, S308, S325, S332, S364 S156, S158, S161, S164, S171, S178, S184, S189–S191, S193–S195, S197, S199– S205, S207, S210–S212, S215, S216, S219, S221, S227, S228, S230, S238, S245, Astrocytes ...... S39, S40, S64, S86, S91, S200, S253–S255, S258, S261–S263, S266, S267, S270, S274, S275, S281–S285, S287, S214, S319, S320, S333, S336, S383, S392 S288, S292, S297, S298, S304–S308, S310, S312, S313, S316–S318, S321, S322, Attachment ...... S118, S212, S361, S375, S405, S406 S325–S327, S329–S333, S335, S338–S340, S343, S354, S357–S359, S363, S365– Attention ...... S2, S6, S7, S23, S27, S28, S33, S36, S367, S369, S371, S373–S375, S377, S379, S393, S405, S406, S416, S420, S421, S51, S56, S63, S66, S75, S80, S81, S83, S96, S98, S99, S106, S107, S111–S114, S432–S435, S441, S443, S444, S448 S116, S118, S121, S123, S141, S144, S145, S151–S156, S160, S163, S164, S171, Behavioral inhibition ...... S5, S78, S109, S111, S307 S172, S175, S185, S188, S193, S196, S199, S204, S207, S209, S237, S239, S245, Behavioral sensitization ...... S190, S328 S247, S250, S260, S265, S274, S275, S286, S305, S309, S311, S313, S319, S333, S341, S349, S367, S368, S371, S388, S395, S399, S415, S417, S421, S428, S429, Behaviour therapy ...... S13, S77, S77, S83, S118, S437, S442 S140, S144–S145, S162, S225–S226, S228–S229, S294, S349 Attention bias ...... S110, S349 Behavioural symptoms ...... S162 Attention set shifting ...... S75 Benzodiazepine ...... S192, S310 Attentional training ...... S144 Bereavement ...... S358, S359 Atypical antipsychotics ...... S65, S96, S97, S102, Beta adrenergic receptors ...... S124–S125, S327–S328 S106, S132, S168, S174, S273, S301, S356, S430 Beta-arrestin ...... S186, S437 Auditory ...... S8, S33, S34, S51, S59, S72, S82, Biomarker ...... S4, S5, S10–S12, S63, S64, S75, S98, S118, S157, S169, S172, S182, S183, S195, S199, S241, S244, S245, S247, S276, S115, S123, S128, S136, S139, S140, S159, S202, S227, S293, S386, S389, S390, S305, S321, S399, S442, S446 S401, S407, S416, S424, S435, S448 Auditory hallucinations ...... S147, S156, S171 Bipolar ...... S5, S11, S15, S16, S39, S40, S44, S61, S62, S65, Autism ...... S5, S10, S17, S25, S27–S31, S39, S40, S68, S69, S89, S90, S114, S123, S124, S127, S128, S152, S153, S160–S162, S211, S45–S47, S55, S60, S70, S84, S87, S116, S135, S150, S151, S198, S217, S229, S220, S222, S239, S246, S247, S251–S253, S298, S299, S302, S303, S343, S240, S259, S260, S308, S337, S405, S448 S345, S349, S354–S356, S358, S359, S383, S389, S391, S392, S396, S397, S400, S402, S411, S418–S421, S424, S426, S445 Autism spectrum disorder ...... S27, S46, S70, S73, S84, S86, S229, S260, S307 Bipolar disorder ...... S5, S15, S28, S29, S38, S39, S42, S48, S56, S57, S60, S61, S68–S70, S90, S92, S113–S117, S123–S127, S132, Autobiographical memory ...... S118, S142 S138, S147, S153, S160, S161, S172, S174, S182, S187, S207, S211, S215, S218– Autonomic ...... S53, S54, S147, S177, S309, S317, S220, S222, S238, S246, S247, S249–S253, S255, S265, S290, S294, S298, S385, S395, S409, S439 S308, S315, S337, S345, S349–S352, S354, S359, S368, S383, S387, S388, S394, Autonomic nervous system ...... S73, S80, S314 S396, S398–S401, S416, S418–S421, S423, S424, S426, S437, S447 Avolition ...... S41 Bipolar major depressive episodes ...... S419

ACNP 50th Annual Meeting Keyword index S486 Bipolar mania ...... S215, S297, S352 Cannabis ...... S49, S94, S113, S243, S273, S301, Birth weight ...... S70, S119, S147, S151, S163, S237 S312, S377, S383, S384, S405 Bk channel ...... S324 Cannabis abuse ...... S301 Blacks ...... S370, S371 Cannabis use status ...... S243 Blast ...... S267, S291, S408 Cardiovascular disease ...... S12, S52, S80, S91, S121, S136, S174, S250, S314, S424, S443 Blood pressure ...... S12, S49, S80, S124, S178, S228, S251, S251, S308, S353, S426, S427 Catalepsy ...... S186, S187, S305, S335 Blood vessels ...... S91, S408 Catecholamines ...... S21, S80, S127, S304 Body dysmorphic disorder ...... S281, S425 Catechol-O-methyltransferase ...... S123, S209, S237, S246 Body mass index . . . S19, S47, S102, S120, S136, S158, S237, S251, S252, S291 Cathinone ...... S441 Body-image disorders ...... S370 Caudate ...... S19, S48, S112, S115, S118, S125, S141, S143, S150, S155, S157, S173, S242, S267–S269, S278, S283, S288, S290, Bonding ...... S72, S73, S361, S389, S405, S438 S291, S365, S381, S382, S386, S387, S391, S394, S397, S398, S402, S404, S413 Borderline personality ...... S269, S270, S375, S376, S446 CB1 ...... S47, S94, S132, S194, S295, S405, S405, S443 BPRS ...... S105–S107, S245, S386, S425 CBT ...... S117, S139, S144, S225, S294 Brain ...... S1–S3, S5–S7, S9, S10, S14, S15, S17–S24, CCK ...... S82, S132 S26–S42, S44–S52, S55–S64, S66–S69, S71, S73, S74, S75–S80, S82, S85–S92, S98, S109–S115, S117–S119, S123, S126, S128, S129, S134, S135, S137, S138, CD-1 mouse ...... S88, S206, S222 S140–S151, S153–S158, S161–S165, S171, S172, S176, S178, S179, S183–S185, CD4 ...... S86, S89, S288, S305 S188, S191–S195, S197, S199–S204, S206–S214, S216–S219, S221–S225, S231, CDH2 ...... S255 S235–S238, S240–S246, S248, S253–S256, S259, S261, S263, S264, S266–S293, CDP-choline ...... S97, S106 S295, S296, S302, S303, S306, S307, S311–S313, S315, S317–S322, S324–S326, S329, S333, S335–S338, S340–S342, S345, S356, S361–S368, S372–S374, S378, Cell adhesion ...... S259, S337 S379, S381, S382, S384–S390, S392–S406, S408, S410, S413, S415, S416, S418, Cell death ...... S2, S64, S91, S207, S212, S215, S273 S422–S424, S428, S430, S431, S433–S438, S440, S441, S443–S448 Cellular ...... S9, S13, S15, S16, S18, S21–S23, S32, Brain imaging ...... S3, S5, S47–S49, S63, S149, S267, S38, S40, S43–S45, S55, S56, S64, S72, S89, S125, S137, S196, S200, S203, S289, S394, S403, S448 S208, S218, S220, S222, S259, S260, S264, S292, S307, S322, S335, S336, Brain metabolism ...... S267, S392, S407 S338, S340, S342, S366, S434, S442, S446 Brain network ...... S109, S149, S273, S282, S396 Cellular transplantation ...... S341 Brain neural network formation ...... S341 Central raters ...... S106 Brain stimulation...... S47, S53, S331, S409, S442 Cerebellum ...... S20, S55, S58, S61, S82, S112, S125, S151, S154, S157, S173, S218, S223, S239, S253, S263, S265, S268, S272, Brain-computer interface ...... S163 S273, S279, S286, S361, S393, S402 Brainstem ...... S7, S110, S150, S179, S402, S403, Cerebral blood flow ...... S221, S273, S289, S319 S415, S440, S448 Cerebral cortex ...... S31, S32, S122, S134, S157, S202, Bromodeoxyuridine ...... S85, S339 S203, S207, S219, S258, S393 Bulimia nervosa ...... S48, S260 Cerebrospinal fluid ...... S138, S234, S293, S317, S383, S417, S429, S435 Bupropion ...... S206, S303, S374, S378, S379, S417, S422 Cessation ...... S171, S179, S200, S322, S329, S379, S380 Buspirone ...... S13, S188 C-Fos ...... S78, S183, S200, S203, S217, S334, S335, S412 Butyrylcholinesterase ...... S14, S223, S312 CGI-I ...... S98, S99, S102, S107, S224–S226, S228, S344, S346, S422 CDH13 ...... S380 C Chemical biology ...... S220 Child ...... S11, S29–S31, S48, S49, S74, S76, S102, C-FOS ...... S78, S183, S200, S203, S217, S334, S335, S412 S109, S118–S120, S135, S150–S152, S160, S162, S198, S222, S229, S232, S238, S241, S250, S251, S259, S262, S264, S287, S296, S297, S350, S357, S388, C-reactive protein ...... S136, S354 S389, S393, S398, S407, S420 C57 ...... S22, S76, S77, S126 Childhood ...... S5, S10, S18, S32, S108, S111, C57BL/6J mice ...... S87, S329, S340, S393 S113, S120, S127, S141, S149, S163, S222, S232, S237, S238, S243, S249, CA1 ...... S7, S8, S84, S137, S223, S278 S256–S258, S261–S262, S370, S371, S380, S406, S408, S409, S442 CAG length ...... S262 Childhood abuse ...... S145, S262 Calbindin ...... S32, S55, S57, S429 Childhood adversity...... S257, S371 Calcium ...... S4, S17, S45, S54, S55, S57, S61, S77, Childhood maltreatment ...... S148, S243, S257, S262 S89, S194, S310, S333, S336, S437 Childhood trauma ...... S23, S24, S48, S127, S142, Calcium sensors ...... S194 S146, S149, S150, S256, S257, S258, S262, S287, S288, S371, S408 Calretinin ...... S32, S204, S205 Children ...... S2, S7, S10, S30, S31, S46, S49, S67, S70, S78, S84, S102, S108, S116, S118–S120, S124, S128, S129, S136, S140, cAMP ...... S185, S186, S223, S258, S336, S424, S437, S440 S146, S148–S153, S155–S158, S163, S228, S229, S237, S249, S252, S261, S263, Candidate genes ...... S21, S130, S131, S132, S253, S261, S376 S264, S270, S273, S296, S306, S310, S326, S349, S350, S359, S387, S388, Cannabinoid ...... S95, S177, S194, S273, S312, S367, S405 S393, S399, S406, S407

ACNP 50th Annual Meeting Keyword index S487 Cholesterol ...... S101, S168, S172, S174, S175, S306, S424, S443 Cocaine addiction ...... S14, S15, S28, S286, S312, Cholinergic ...... S47, S62, S67, S93, S96, S106, S330, S331, S338, S339, S376, S402 S199, S236, S320, S326, S341, S379, S422, S423 Cocaine dependence S6, S157, S176, S285, S331, S334, S370, S371, S403, S425 CHRNA3 ...... S373, S377, S379 Cocaine self-administration . . . . . S9, S13–S15, S50, S188, S190–S192, S316, CHRNA5 ...... S284, S372, S373 S322, S328–S331, S333, S334, S339 Chronic ...... S7, S13, S14, S28, S37, S38, S62, Cocaine toxicity ...... S312 S63, S66, S73, S75, S79, S82, S85, S87–S90, S92, S97, S100, S101, S106, S130, Cocaine-seeking behavior . . . . . S15, S189, S192, S310, S311, S327, S330, S331 S132, S134, S137, S139, S145, S153, S159, S161, S165, S166, S169, S171, Cochrane review ...... S359 S172, S174, S187–S192, S194, S195, S199–S205, S211, S215, S226, S229, S245, Cognition ...... S4, S6, S8, S13, S20, S22, S26, S31, S63, S66, S246, S248, S250, S252, S255, S258, S265, S269, S272, S274, S276–S278, S67, S91, S94, S96, S99, S106, S117, S131, S134, S157, S170–S173, S175, S182, S282, S283, S286, S288, S290, S291, S295, S306, S308, S314, S322, S324, S184, S209–S211, S215, S220, S224, S236, S237, S242, S247, S274, S276, S326, S328, S329, S331–S333, S339, S340, S342, S364, S366, S367, S372, S374, S278, S281, S282, S293, S317–S320, S341, S350, S366, S374, S382, S392, S407, S381, S382, S384, S387, S392, S404–S408, S410, S412, S415, S418, S431, S434, S435–S437, S439 S443, S444, S447, S448 Cognitive and Physical Functioning Questionnaire ...... S347, S416 Chronic early neglect ...... S406 Cognitive behavioral therapy ...... S117, S139, S144, S225, S294 Chronic pain ...... S1, S17, S36, S37, S124, S159, S234, S309, S311 Cognitive control ...... S28, S112, S155, S195, S199, S281, S286, Cigarette smoking ...... S20, S175, S287, S376, S404 S365, S366, S385 Cingulate ...... S35, S49, S53, S57, S58, S110, Cognitive function ...... S4, S48, S49, S70, S75, S140, S147, S157, S241, S267, S270, S341, S386, S394, S400, S402, S407 S81, S95, S96, S113, S115, S116, S161, S169, S171, S177, S188, S209, S210, Cingulate gyrus ...... S54, S141, S171, S254, S318 S215, S217, S231, S237, S243, S246, S274, S281, S287, S321, S350, S351, Cingulum ...... S156, S157, S191, S243 S362, S366, S419 Circadian rhythms ...... S15, S92, S217, S324, S330 Cognitive impairment ...... S3, S4, S100, S107, S108, Citalopram ...... S57, S119, S121, S300, S304, S114, S116, S118, S172, S182, S183, S185, S217, S233, S236, S243, S276, S279, S305, S368, S386, S431, S437 S346, S349, S358, S430 Cognitive reappraisal ...... S109, S269, S289 CK-1 ...... S375 Cognitive therapy ...... S139, S162 Clinical ...... S1–S3, S5, S10–S14, S16, S24–S26, S28, S30, S34, S36, S37, S40, S41, S43–S45, S52, S57–S60, S62, S64–S67, Cognitive training ...... S143, S247, S248, S439 S69, S70, S72, S75, S77, S84, S88–S90, S94–S105, S109–S111, S113–S118, Comorbidity ...... S69, S80, S111, S149, S159, S252, S259, S120–S123, S127–S130, S132–S136, S138, S139, S141, S144, S146, S150, S152, S276, S277, S288, S315, S334, S341, S359, S370 S153, S157, S159–S176, S178–S182, S184, S187, S189, S192, S195, S196, S201, Comparative effectiveness ...... S349, S354 S203–S205, S208, S210, S224–S233, S236, S237, S239, S240, S245–S247, S249–S252, S255, S260, S261, S263, S268, S270, S272, S273, S276–S280, Compensation ...... S43, S100, S126, S130, S171, S174, S282, S284, S287, S291–S307, S309, S317, S320, S330, S334, S335, S337, S206, S254, S264, S280, S348, S413, S416, S425 S342–S349, S351, S352, S354, S356–S360, S367, S370–S374, S379–S384, S386, Complicated grief ...... S406, S349, S358, S359, S406, S407 S388–S390, S394, S395, S397, S399, S400, S402, S405, S408–S411, S413, Compulsive ...... S7, S9, S28, S40, S47, S75, S79, S164, S226, S414, S416–S425, S427, S428, S431, S432, S435–S438, S444, S446, S448 S297, S308, S310, S338, S339 Clinical decision making ...... S349, S351 Computational ...... S27, S48, S72, S194, S207, S310, S321, S365 Clinical features ...... S29, S162, S239, S388 COMT ...... S21, S22, S49, S124, S126, S209, S210, Clinical global impression scale ...... S345, S352 S238, S247, S286, S297, S320, S337, S338, S379 Clinical high risk ...... S10, S11, S241, S245, S278, S384, S409 COMT inhibitor ...... S209, S210, S297 Clinical staging ...... S418 Conditioned cues ...... S322 Clinical trial ...... S3, S14, S34, S37, S69, S96, Conditioned place preference ...... S13, S36, S81, S193, S102, S106, S122, S123, S133, S135, S142, S166, S186, S230, S231, S235, S240, S217, S316, S325, S327, S330, S332, S339, S440 S284, S289, S300, S346, S347, S349, S357, S360, S361, S378, S380, S394, Conditioning . . . S17, S18, S21, S23, S50, S54, S55, S56, S67, S78, S130, S140, S404, S412, S421–S425 S143, S196, S212, S217, S223, S295, S308, S314, S316, S327, S332, S439 Clinical trial methodology ...... S231, S361 Conflict ...... S11, S43, S54, S60, S108, S109, S136, S140, S141, CLOCK ...... S15, S137, S138, S330, S331 S160, S221, S230, S271, S272, S287, S355, S365, S365, S396 Clock ...... S92, S330, S331 Cognition ...... S4, S6, S8, S20, S22, S26, S31, CLOCK gene ...... S330, S331 S33–S34, S63, S66–S67, S91, S95–S96, S99–S100, S107, S117, S118, S132, S135, S147, S157, S170–S172, S174, S176, S183, S209–S211, S220, S224, S237, Clonidine ...... S169, S181, S331, S332 S271, S274, S277–S279, S281–S282, S294, S318, S320–S321, S341, S351, S361, Clozapine ...... S121, S132, S169–S171, S175, S183, S366, S375, S382, S385, S393, S407, S435, S437, S439 S184, S186, S208, S210, S215, S434, S438 Connectivity ...... S5, S16, S23, S29, S30, S36, S39, S41, CNTNAP2 ...... S29, S198, S259, S260 S68, S69, S93, S110, S112, S113, S144, S145, S147–S150, S152, S154, S155, S157, CNV ...... S28, S29, S46, S60, S61, S62, S84, S259, S260, S264, S292 S192, S238, S254, S255, S265, S270, S271, S273, S277, S281, S282, S290, S318, S320, S321, S362, S368, S381, S386, S389, S394, S397–S401, S446 Cocaine...... S2, S7, S9, S13–S15, S21, S28, S35, S36, S47, S50, S67, S157, S158, S165, S166, S177, S180, S189–S194, Consolidation ...... S1, S82, S190, S235, S267, S447 S196, S197, S211, S216, S286, S290, S311–S313, S316, S319, S322, S325, Context .S5, S9, S17, S28, S36, S44, S54, S63, S78, S79, S82, S110, S129, S143, S327–S334, S338, S342, S371, S377, S378, S402–S405, S426, S427, S432, S433, S152, S158, S159, S174, S178, S186, S187, S189, S217, S218, S225, S245, S440, S441 S254–S255, S260, S262, S263, S264, S270, S271, S274, S275, S278, S299,

ACNP 50th Annual Meeting Keyword index S488 S310, S317, S327, S328, S331, S352, S357–S359, S386, S396, S406, S414, Cyclothymic disorder ...... S252 S424, S444 Cynomolgus macaque ...... S408 Context processing ...... S245, S270 Cytokine ...... S30, S43, S86, S88, S202, S264, S300, S317, S392 Contextual factors ...... S349 Cytokines ...... S37, S38, S86, S88, S125, S137, Control . . . . S4–S6, S8, S11, S15–S19, S22, S28–S32, S34, S40, S42–S50, S52, S202, S264, S315, S317 S54, S61, S62, S65, S66, S68, S71, S77, S80, S81, S83–S85, S88–S92, S94, S109–S113, S118, S119, S123, S134, S136–S139, S141, S142, S144, S147, S148, S150, S151, S153, S154, S156–S159, S164, S170, S190–S192, S195, S199–S202, D S205, S207, S209, S213, S216–S220, S222, S224, S225, S227, S230, S231, S237–S241, S244–S248, S258, S259, S264, S266, S268, S270, S275, S277, S279, S281–S283, S285, S287–S290, S292, S297, S302, S303, S306, S311, S313, D1 ...... S6, S13, S36, S41, S90, S190, S213, S214, S315, S317, S319–S322, S325, S330, S333, S335–S340, S352, S362, S363, S365, S333, S366, S383, S432, S440, S441, S443 S366, S368, S371–S373, S375, S376, S383–S387, S390, S393, S395–S398, S400, S402, S403, S405, S408–S410, S413, S415, S419, S423, S428, S432, D2 ...... S9, S13, S22, S47, S84, S95, S173, S438–S440, S442–S447, S449 S213, S214, S302, S327, S333, S366, S375 Copy number variation ...... S29, S46, S60, S292 D2 receptor ...... S9, S10, S22, S50, S173, S286, S320, S333, S366, S379 Corpus callosum ...... S34, S152, S275, S288, S397–S398 D2/D3 ...... S198, S199, S268, S308 Correlation ...... S19, S51, S62, S70, S89, S90, S102, S110, S111, S122, S131, S136, S153–S155, S161–S163, S201, S219, S231, D2R ligands ...... S187 S238, S241, S248, S265, S270, S271, S273, S277, S290, S292, S293, S315, S326, D3 ...... S13, S199 S354, S361, S368, S380, S384–S386, S389, S390, S394, S396, S398, S400, D3 dopamine receptors ...... S268, S308 S413, S429 D3 receptor ...... S13 Cortex ...... S1, S5, S7, S15, S16, S20–S22, D4 ...... S13, S309 S26–S28, S32–S36, S38, S40, S42, S44, S45, S49, S50, S53, S55, S57, S58, S61–S63, S68, S71–S73, S77–S80, S82–S84, S89, S90, S92, S109, S110, S113– D5 ...... S13, S333 S115, S119, S123, S126, S127, S134–S136, S138, S140–S142, S145, S146, S148, D-amphetamine ...... S20, S58, S426 S150–S152, S154, S155, S157, S163, S165, S166, S174, S180, S182, S184, S185, D-amphetamine prodrug ...... S100 S192–S196, S200, S203–S205, S207, S209, S210, S212, S213, S215, S219–S221, S223, S231, S238, S241–S243, S246, S253, S255–S257, S264–S272, S274, S275, D-Serine ...... S58, S59, S208, S214, S304 S278–S282, S285, S286, S288, S290, S295, S297, S302, S307, S310–S312, DARPP-32 ...... S213, S220, S221, S375, S381 S315, S318, S319, S325, S327, S328, S332, S333, S335, S337, S340–S342, DASB ...... S282 S361–S366, S368, S382, S384–S388, S390–S394, S396–S403, S408, S411, DBS ...... S18, S19, S90, S122, S123, S166, S343 S416, S423, S424, S430, S434, S436, S440, S445, S447–S448 De novo mutation ...... S60, S250, S259, S260 Cortical development ...... S156, S219 Decision making ...... S27, S28, S122, S297, S351 Cortical dopamine ...... S20, S320 Deep brain stimulation ...... S18, S28, S90, S166, S343 Cortical thickness ...... S280, S389 Default mode ...... S154, S270 Corticosterone ...... S19, S43, S54, S202, S324, S341 Default mode network ...... S144, S156, S270, S362 Corticotropin ...... S81, S126, S203, S212, S327 Deficit ...... S11, S32, S35, S42, S43, S47, S66, S76, Corticotropin-releasing hormone ...... S43, S262 S80–S83, S91, S95, S98, S151, S153, S155, S156, S160, S179, S182–S185, S199, Cortisol ...... S3, S49, S110, S145, S159, S160, S177, S257, S200, S209, S210, S213, S237, S240, S247, S258, S265, S275, S280, S288, S262, S315, S354, S378, S400, S406–S409 S305, S312, S314, S319–S321, S436 Cortisol awakening response ...... S110, S406, S407 Deltafosb ...... S47 COX-2 ...... S92, S337 Dendrites ...... S6, S220, S221 CPFQ ...... S416, S417 Dendritic morphology ...... S208 CPT ...... S98, S152 Dendritic spines ...... S40, S81, S84, S85, S217, S329, S339, S341 Craving ...... S7, S13, S20, S28, S165, S166, S178, Denicotinized tobacco ...... S404 S235, S283, S322, S333, S339, S367, S377–S379, S384, S428 Dependence ...... S7, S50, S116, S139, S164, S176, C-reactive protein ...... S354 S179, S180, S188, S191, S195, S243, S277, S284, S291, S292, S306, S324, S329, CRF ...... S55, S56, S76–S78, S81, S167, S203, S204, S327, S328, S331, S331, S332, S334, S340, S341, S367, S369–S371, S377, S378, S380, S404, S332 S405, S427 CRH ...... S43, S172, S262, S263, S378 Depressed ...... S15, S16, S38–S40, S45, S83, S88, CSF ...... S4, S11, S34, S48, S63, S128, S139, S154, S89, S91, S93, S94, S115, S117–S120, S122, S124, S136–S138, S159, S161, S162, S160, S288, S293, S326, S435 S172, S200, S203–S205, S229, S230, S247, S295, S298, S300, S301, S304, S331, S345, S346, S348, S354, S356, S357, S360, S365, S387, S389, S390, Csf oxytocin ...... S160 S395–S397, S399, S400, S411–S413, S420, S424 Cue reactivity ...... S20, S284, S311 Depression ...... S3, S12, S15, S16, S18, S19, S28, Cues ...... S6, S20, S28, S50, S52, S54, S78, S109, S37–S40, S42–S45, S48, S56, S57, S62, S65, S69, S70, S78, S81–S83, S85, S114, S144, S164, S165, S199, S211, S239, S272, S284, S289, S319, S322, S323, S86, S88–S91, S93, S94, S98, S99, S101, S109, S111, S115, S117–S119, S326, S331, S332, S339, S361, S363, S403, S404, S428, S439 S122–S128, S136–S140, S143, S144, S146, S148, S149, S159, S161–S163, S169, Cyclic GMP ...... S432 S172, S173, S176, S200–S205, S227, S229–S231, S235, S238, S239, S250, S252,

ACNP 50th Annual Meeting Keyword index S489 S256, S259, S261, S263, S264, S266, S267, S282, S284, S290, S294–S296, S290–S292, S297, S303, S305, S308–S310, S318, S319, S322, S325, S328, S330, S298–S305, S308, S311, S315, S317, S321, S325, S334, S335, S342–S354, S333, S334, S338, S340, S363, S374, S376, S378, S379, S381, S383, S384, S397, S356–S360, S365, S371, S373, S386–S390, S392, S395, S396, S398, S398, S402, S404, S405, S414, S415, S431, S432, S437, S438, S440, S400–S402, S406, S411–S415, S417–S426, S430–S434, S437, S443, S444, S442–S444, S446 S447, S448 Dopamine beta hydroxylase ...... S83, S376 Depressive phenotype ...... S88, S204 Dopamine D3 ...... S13 Designer drug ...... S216 Dopamine neurons ...... S35, S54, S92, S178, S192, S205, S267 Desipramine ...... S79, S80, S304 Dopamine receptor D1 ...... S383 Desvenlafaxine ...... S296 Dopamine receptor D2 ...... S213, S268, S308, S330, S382, S402, S438 Development ...... S2, S4, S5, S9–S12, S14, S15, Dopamine receptors ...... S13, S213, S216, S268, S308, S383 S17, S18, S21–S27, S30, S32, S33, S36, S39, S40, S42–S45, S47–S50, S54, S56, Dopamine transporter ...... S41, S60, S189, S215, S339, S340, S379 S57, S59, S60, S63, S67, S69, S70, S73, S76, S79, S83–S90, S95, S98, Dorsal hippocampus ...... S189 S100–S102, S104, S106, S108, S109, S115, S118, S120, S123–S126, S131–S133, S135, S137–S139, S141, S142, S145–S149, S151, S152, S154, S158, S159, S164, Dorsal raphe ...... S59, S86, S203 S166, S167, S171, S174, S180, S184, S191, S193, S194, S201, S202, S205, S206, Dorsal raphe nucleus ...... S409 S208–S220, S222, S224–S227, S230, S231, S235–S238, S240, S242, Dorsolateral prefrontal cortex ...... S8, S26, S32, S34, S248–S251, S253, S258, S259, S261, S263–S265, S270, S273, S275, S284, S89, S114, S126, S164, S220, S222, S242, S248, S265, S266, S270, S271, S275, S285, S287, S292, S295, S296, S298–S301, S303, S304, S311, S313, S315, S317, S276, S279, S281, S286, S290, S366, S382, S385 S323, S324, S326, S327, S332–S334, S336–S339, S341, S344, S346, S349–S351, S353, S354, S356–S358, S362, S366, S367, S372, S374, S380, S381, S384, S385, Dorsolateral striatum ...... S216, S308, S330 S387, S388, S390, S394, S403, S405–S407, S410, S412, S414, S416–S418, Dorsomedial striatum ...... S216, S330, S338 S430–S435, S437–S439, S443, S446, S447 Dosage ...... S14, S148, S161, S168, S175, S228, S410, Developmental programming ...... S59 S411, S421 Dex/CRH test ...... S257 Dot probe ...... S111 Diabetes ...... S12, S52, S121, S159, S174, S175, Double-blind ...... S7, S24, S37, S44, S62, S67, S95–S104, S208, S387, S388 S106–S108, S113, S127, S128, S136, S159, S161, S168, S170, S173, S176, S178, S179, S195, S223–S227, S229–S234, S274, S283, S297, S299–S301, S303, Diagnosis ...... S2, S11, S20, S23, S26, S30, S38, S304, S342, S344–S346, S348–S353, S356, S357, S360, S367, S378, S380, S93, S94, S98, S105, S111, S112, S115, S120, S126, S128, S130–S132, S134–S136, S404, S415, S422, S423, S426–S429, S440 S141, S150, S152, S153, S155, S159, S163, S168, S172–S174, S211, S232, S235, Double-blind trial ...... S102, S229, S232 S243, S246, S247, S249, S250, S257, S261, S262, S265, S269–S271, S275, S277, S280, S309, S321, S352, S354, S356, S376–S379, S383–S385, Down syndrome ...... S154 S391, S448 DRD2 ...... S22, S132, S320, S321, S337, S338, S379, S380 Diagnostic criteria ...... S2, S226, S252, S367, S369 DRD4 ...... S261, S262, S368, S369, S379 Diet ...... S8, S9, S47, S161, S175, S193, S194, S207, DRD4 gene ...... S379 S208, S229, S336, S337, S348 DREADD ...... S216 Difficult-to-treat ...... S356 Drinking ...... S7, S12, S52, S166, S178, S181, S188, Diffusion imaging ...... S156, S393, S396 S189, S194, S200, S208, S235, S253, S283, S284, S306, S324, S325, S329, Diffusion spectrum imaging ...... S151 S338, S340, S341, S366, S382, S428–S429 Diffusion tensor imaging . . . S146–S148, S152, S153, S156, S157, S275, S280, Drug abuse ...... S50, S144, S177, S180, S189, S225, S226, S230, S238, S287, S288, S303, S311, S322, S326, S339, S344, S353, S355, S293, S333, S393, S398, S399, S401 S368–S370, S373, S403, S417 Dimensions ...... S2, S3, S6, S36, S139, S188, S214, Drug combination ...... S421 S279, S292, S316, S367–S368 Drug cues ...... S216, S322 Disability ...... S39, S46, S84, S105, S106, S115–S117, S156, S233, S244, S250, S252, S259, S260, S281, S282, S303, S315, Drug dependence ...... S6, S235, S283, S330, S334, S373 S347, S371 Drug development ...... S10, S24, S25, S36, S37, DISC1 ...... S8, S22, S128, S129, S214, S219, S263 S59, S92, S98, S202, S225, S226, S229, S231, S246, S277, S294, S310, S329, S357, S358, S361, S382, S395, S419 Discontinuation ...... S58, S65, S101, S102, S135, S136, S168, S173, S175, S176, S223, S303, S345, S347, S349, S350, S353, Drug development tools ...... S358 S419, S420 Drug self-administration ...... S50, S78, S189, S192, S216, S287, Disgust ...... S108 S322, S339 Disinhibition ...... S21, S158, S211, S227, S416 Drug therapy ...... S139, S146, S163, S218, S263 Dispersion ...... S275 D-serine ...... S58, S59, S208, S214, S304 DKO ...... S312 DSM-5 ...... S2, S226, S252 DNA methylation ...... S18, S22, S26, S73, S78, S92, S254, S327, S372 DTI ...... S3, S5, S6, S10, S23, S41, S51, S146–S148, S152, S156, S157, S191, S243, S244, S268, S271, S273, S275, S277, S281, S292, S393, Dopamine ...... S6, S9, S13–S15, S19–S22, S35, S396–S398 S41, S47–S50, S54, S72, S73, S75–S78, S83, S84, S90, S92, S95, S100, S107, Dual receptor antagonism ...... S319 S143, S153, S155, S178, S179, S182, S184–S187, S189–S192, S195, S196, S198, S199, S203–S206, S209, S213, S216, S218, S221, S224, S225, S235, S238, S239, Duration of untreated psychosis ...... S104 S242, S245, S247, S261, S268, S269, S272, S273, S276, S284, S286–S288, Dynamic causal modeling ...... S145, S320

ACNP 50th Annual Meeting Keyword index S490 Dynorphin ...... S216, S433, S439, S441 Epigenome ...... S263, S292, S327 Dysbindin ...... S22, S213, S444 ERK ...... S56, S79, S80, S336, S431, S443 Dysphoria ...... S200, S440 ERP ...... S28, S33, S59, S125, S144, S245, S248 Escalation ...... S14, S15, S95, S153, S187, S329, S334, S339, S422, S441 E Escitalopram ...... S3, S296, S301, S346, S351, S394, S416, S422, S422 Estrogen ...... S23, S73, S200, S201, S257, S268, S317, S407, S408 Ethanol ...... S79, S178, S188, S189, S191, S194, S195, Early age-at-onset ...... S60, S123 S306, S312, S324, S325, S329, S332–S334, S338, S340–S342, S366, S372, S373, Early life stress ...... S126, S255, S257, S327 S375, S428 Early loss ...... S158 Ethanol-infusion ...... S177 Eating disorders ...... S19, S55, S261 Evoked responses ...... S36, S196, S321 Ecstasy ...... S282, S342, S427 Evolution ...... S1, S10, S52, S172, S263 ECT ...... S57, S117, S122, S172, S230, S231, EVP-6124 ...... S171, S185 S363, S386, S399, S409, S410–S412, S433 Excitability ...... S37, S84, S90, S165, S194, Educational attainment ...... S370 S210, S212, S216, S306, S329, S331, S338, S341 EEG ...... S3, S24, S32, S33, S44, S72, Executive ...... S6, S52, S114, S115, S123, S157, S94, S163, S195, S200, S212, S234, S240, S248, S314, S385 S172, S176, S199, S243, S246, S272, S276, S277, S320, S350, S353, S366, S368, S399, S402 Efficacy ...... S7, S11–S14, S34, S36, S37, S39, S42–S45, S58, S62, S64, S69, S72, S75, S80, S83, S96–S98, S100–S102, S106, S107, Executive dysfunction ...... S114, S158, S235, S320, S353 S120, S122, S127, S131, S155, S161–S163, S167, S169, S170, S173, S175, S178, Executive function ...... S3, S5, S28, S66, S83, S98, S178, S181–S183, S186, S187, S192, S204–S206, S212, S223–S227, S229–S231, S114, S116, S135, S152, S171, S175, S176, S200, S237, S265, S276, S286, S320, S233, S235, S274, S276, S285, S296–S299, S301–S304, S307, S311, S317, S319, S350, S351, S353, S367, S398 S331, S332, S335, S343–S349, S351–S354, S356, S357, S359, S360, S403, S410– Executive function impairment ...... S357 S412, S418, S419, S421, S424, S432, S434, S435, S437, S443, S445 Exercise ...... S94, S100, S160, S174, S357, S413, S424 Egr3 ...... S183, S184 Exome sequencing ...... S29, S46, S65, S123, S259, S260 Electroconvulsive therapy ...... S116, S156, S386, S399, Expectation bias ...... S94 S409–S411, S433 Expression ...... S2–S5, S8, S9, S14, S16–S19, S21–S24, S26, S30–S32, Electrophysiology ...... S56, S60, S89, S182, S194, S196, S210, S35–S38, S40, S42–S44, S47, S48, S50, S54–S56, S60–S64, S67, S68, S310, S329, S366 S70–S74, S76–S86, S88–S92, S94, S97, S109, S116, S122–S124, S128, S132, Elevated plus maze ...... S75, S77, S80, S90, S200, S304, S306, S134, S135, S138, S141, S142, S144, S161, S172, S184, S185, S187–S191, S331, S335, S431, S433, S445, S448 S193, S197, S198, S200, S201, S203–S205, S207, S208, S211–S223, S239, EMG ...... S141 S256–S259, S262, S264, S265, S271, S279, S293, S306, S307, S310, S311, S314, S317, S322, S323, S325, S326, S329, S331, S333–S338, S341, S342, S361, S372– Emotion ...... S6, S22, S23, S33, S34, S41, S53, S68, S69, S375, S378, S381–S384, S393, S400, S402, S403, S405, S409, S413, S423, S73, S80, S81, S87, S109, S113, S116, S130, S131, S134, S140, S144, S148, S153, S430, S431, S433, S434, S440, S443–S445, S447 S153, S155, S157, S248, S264, S269, S319, S361, S388, S392, S395, S399, S401, S405, S406, S423, S427, S438, S444 Extended amygdala ...... S7, S81, S118, S241, S441 Emotion regulation ...... S68, S153, S164, S269, S401 Extinction ...... S1, S11, S14, S18, S19, S23, S35, S50, S54, S55, S67, S77, S83, S84, S141–S144, S190, S191, S193, S194, S211, Emotional processing...... S96, S109, S139, S153, S157, S177, S257, S263, S296, S313, S314, S322, S325–S328, S330, S332, S339, S364, S403 S265, S318, S427 Eye-tracking ...... S27 Emotional stimuli ...... S21, S68, S109, S139, S143, S177, S395, S422, S423, S426 Endocannabinoid ...... S95, S194, S295, S383, S405, S442 F Endocannabinoid system ...... S95, S295, S383, S405 Endophenotype ...... S30, S52, S63, S70, S123, S129, S130, S133, S134, S244, S256, S264, S265, S311, S375, S405 Face processing ...... S33, S144, S248, S387, S395 Endothelial functioning ...... S97 Faces ...... S5, S22, S29, S33, S69, S108, S109, S116, S140, S144, S153, S178, S248, S318, S388, S395, S401 ENT1 ...... S338 Facial affect ...... S33, S96, S116, S123, S248, S439 Environment ...... S12, S27, S37, S49, S50, S110, S127, S148, S151, S158, S162, S192, S204, S217, S253, S258, S261, Factorial design ...... S186, S349 S267, S309, S316, S318, S322, S327, S359, S373, S394, S415, S427, FAM111A ...... S373 S439 Familial risk ...... S68, S119, S389, S409 Environmental enrichment ...... S78, S160, S316 Familiarity ...... S41 Enzyme ...... S14, S15, S22, S42, S83, S126, S127, S132, Family ...... S11, S20, S30, S39, S41, S62, S180, S209, S238, S261, S297, S312, S313, S342, S379, S384, S429, S442, S448 S68–S70, S77, S80, S90, S100, S102, S119, S124, S129, S133, S147, S171, S181, Epidemiology ...... S69, S70, S226, S370 S190, S194, S199, S221, S243, S246, S252, S254, S260, S263, S264, S268, Epigenetic ...... S5, S17, S18, S22, S23, S26, S27, S269, S273, S278, S283, S292, S300, S309, S310, S317, S325, S335, S342, S363, S37, S44, S55, S73, S78, S92, S123, S130, S202, S250, S258, S265, S327, S335, S370, S374, S375, S381, S391, S400, S401, S407, S413, S414, S439 S337, S341, S372 Family history alcoholism ...... S283

ACNP 50th Annual Meeting Keyword index S491 Family studies ...... S46, S70, S254 Frontal ...... S21, S27, S32, S34, S41, S46, S58, S77, Family therapy ...... S401 S83, S91, S110, S112–S114, S119, S126, S127, S129, S148, S150, S151, S155, S158, S165, S205, S210, S227, S236, S238, S241, S243, S254, S255, S264–S266, Fast-scan cyclic voltammetry ...... S81, S203, S216, S363 S268, S270, S271, S274, S275, S280, S281, S283–S285, S288, S290, S297, Fat intake ...... S261 S307, S310, S320, S336, S342, S345, S361, S362, S382, S385, S387–S389, S396, Fatigue ...... S112, S136, S178, S199, S228, S251, S398, S401, S403, S411, S433 S346, S347, S391, S407, S416, S447 Frontal lobe ...... S91, S147, S265, S320, S395, S414, S423 Fear ...... S1, S2, S11, S16–S19, S21, S23, S34–S36, Frontoparietal ...... S318, S365 S53–S55, S60, S77–S79, S82, S108, S111, S118, S141–S144, S153, S217, S225, Frontostriatal tracts ...... S152 S256, S296, S313, S314, S318, S335, S364, S388, S406, S407, S447 Functional capacity ...... S99, , S241, S293 Fear conditioning ...... S16–S18, S21, S23, S54, S55, S66, S72, S79, S80, S82, S83, S110, S141, S143, S212, S217, S218, S223, S296, Function ...... S1, S4–S9, S11, S13, S14–S24, S27, S313, S314, S363 S29–S31, S34, S35, S37, S39, S40, S44, S45, S47–S53, S55, S58–S62, S65, S67– S69, S71, S76, S77, S80, S81, S83–S85, S87, S88, S91, S97, S98, S106, S107, Fear extinction ...... S35, S55, S77, S80, S143, S144, S314 S110, S114–S119, S122, S123, S126, S130, S132, S137–S142, S148, S155, S156, Feast ...... S19, S399, S410, S411 S159–S161, S171, S172, S175–S178, S180, S181, S184, S185, S187–S189, S193– Feedback...... S12, S49, S54, S95, S111, S118, S164, S195, S198, S201, S204, S208–S210, S212, S214, S218–S221, S233, S234, S237, S190, S241, S242, S262, S266, S290, S309, S319, S329, S365, S393, S402, S238, S241, S243, S246, S248, S254, S255, S259, S260, S262, S264, S266– S410 S268, S271, S273–S276, S278, S279, S281–S284, S286–S290, S298, S303– S305, S308–S311, S313, S314, S318, S320, S325, S333–S338, S341, S345, S351, Female ...... S5, S55, S56, S70, S72, S93, S107, S121, S363, S365–S367, S370, S373–S375, S377, S379, S381, S382, S390, S392, S393, S124, S127, S129, S131, S134, S138, S140, S141, S145, S146, S153, S155, S158, S395–S397, S399, S404, S407, S409, S410, S413, S428, S431, S433, S436, S159, S165, S167, S176, S200–S202, S215, S222, S226, S232, S234, S239, S249, S444, S448 S250, S253, S257, S258, S261, S261, S263, S266, S268, S270, S275, S276, S287, S290, S292, S297, S302, S305, S308, S314–S317, S324, S327–S329, S337, Functional ...... S2, S3, S5, S6, S10, S15, S20–S24, S347, S352, S361, S364, S371, S378, S381, S395, S396, S408, S425, S436, S438 S27–S29, S32, S33, S36, S37, S40, S45–S49, S51–S54, S56, S60–S64, S68, S69, S76–S78, S83, S84, S86, S90, S93, S95, S97, S99, S105, S110, S112, S117, Fentanyl ...... S311, S312, S375 S119, S125, S126, S129, S131, S132, S134, S143, S146–S148, S150–S153, S155– FESZ ...... S245 S157, S170, S183, S185, S188, S192, S193, S195, S198, S199, S202, S206, S209, Fetal ...... S26, S30, S31, S59, S60, S119, S144, S163, S213, S218, S221–S224, S231, S232, S234, S238, S240, S242, S243, S246, S250, S220, S237, S315, S336, S337, S341, S347, S414, S443 S253–S255, S257, S261–S263, S266–S268, S270–S274, S277–S279, S281– S283, S286, S289, S290, S292–S294, S303, S305, S307, S310–S312, S318– Fetal alcohol spectrum disorder ...... S341 S321, S333, S336, S338, S339, S341, S355, S357, S361–S363, S373, S374, S377, Fetal development ...... S10 S379–S381, S384, S386, S388, S391, S395, S398, S399, S401, S402, S405, Fetal programming ...... S315 S409, S415, S418–S420, S423, S424, S432, S437–S440, S442, S447, S448 Fibromyalgia ...... S234, S308 Functional connectivity ...... S10, S37, S68, S69, First and second generation antipsychotics ...... S169 S110, S112, S113, S145, S148–S151, S154, S155, S157, S241, S254, S265, S268, S270, S271, S273, S277, S285, S290, S291, S318, S361, S368, S388, S389, S391, First episode ...... S11, S49, S104, S128, S169, S175, S240, S244, S274, S398, S400, S401, S415 S277, S399 Functional magnetic resonance imaging ...... S48, S49, S51, First-generation antipsychotics ...... S175 S69, S109, S114, S118, S118, S139, S143, S145, S150, S151, S164, S241, S265, FKBP5...... S23, S24, S49, S256, S262, S378 S267, S271, S272, S278, S279, S285, S286, S289, S362, S365, S386, S387, S391, Fluoxetine ...... S79, S83, S119, S201, S205, S395, S400, S401–S403, S414 S206, S252, S265, S265, S297, S301, S307, S314, S346, S425, S425, S431 Functional neuroimaging ...... S5, S73, S111, S153, S245, S266, FMRI ...... S3–S6, S13, S22–S25, S27, S28, S33, S41, S47–S49, S51, S317, S364, S385 S54, S68, S69, S109–S115, S119, S140, S143–S145, S148, S150, S151, Functional outcome ...... S34, S40, S117, S174, S242, S418 S153, S154, S162–S165, S178, S239, S241, S242, S246, S248, S254, S255, Functional selectivity ...... S106, S185, S192, S333, S437 S265–S279, S281, S283–S287, S289–S291, S298, S315, S318, S319, S321, Functioning...... S3, S8, S28, S30, S32–S34, S48, S74, S76, S361–S363, S365, S366, S368, S386, S388, S389, S394–S396, S400, S95, S96, S99, S104, S106, S108, S112–S114, S117, S121, S133, S143, S149, S401–S404, S415, S423 S150, S159, S168, S170, S172, S176, S177, S180, S224, S225, S227, S229, S233, FMRP ...... S307, S325 S236, S238, S239, S243–S245, S258, S272, S276, S283, S286, S290, S293, Folate ...... S97, S232, S233 S294, S296, S298, S301, S303–S305, S326, S333, S336, S342, S345–S347, S350, S352, S354, S355, S362, S365, S381, S383, S386, S399, S400, S410, S416, S417, Follow-up ...... S24, S61, S68, S69, S77, S94, S422, S431, S438, S442, S448 S105, S115, S117, S129, S135, S160, S163, S168, S174, S192, S224, S226, S232, S236, S237, S246, S246, S250, S251, S260, S272, S273, S277, S280, S300, G S357, S378, S387, S400–S402, S409, S411, S424, S427 Food intake ...... S9, S19, S106, S186, S261, S266, S297 GABA ...... S6, S32, S34, S35, S42, S43, S53, S59, S72, Food reward ...... S8, S9, S41, S48, S188, S215, S266, S372, S373 S81, S94, S134, S135, S164, S185, S192, S195, S197, S204, S205, S218, S219, Foraging ...... S321 S260, S283, S305, S312, S329, S333, S334, S376, S384–S386, S390, S404, Forced swimming test ...... S431 S405, S428, S445 FOXO3a ...... S202, S203 GABA B agonist ...... S289, S404 Fragile X syndrome ...... S259, S307 GABA-A receptor ...... S42, S135, S329 Free water ...... S268 Gabapentin ...... S278

ACNP 50th Annual Meeting Keyword index S492 GABRA2 ...... S283, S366 Genetics ...... S2, S3, S5, S11, S28, S29, S51, S60, GAD67 ...... S42, S71, S72, S203–S205, S219, S222, S384, S385 S65, S70, S124, S130, S131, S134, S177, S198, S255, S264, S284, S315, S316, S368, S369, S378, S380 GAF ...... S96, S108, S114, S168, S172, S245, S272, S301, S304, S409 Geometry ...... S275, S276, S399, S411 Gain ...... S18, S28, S41, S67, S107, S118, S145, S146, S208, S210, S221, S222, S267, S370, S439, S441 Geriatric ...... S230, S231, S236, S397 Galanin ...... S200, S378 Gestalt ...... S248 Galantamine ...... S97, S106 Glia ...... S38, S39, S43, S93, S200, S293, S392 Gambling ...... S13, S28, S215, S284, S297, S298, S309, S342, S368 Global ...... S3, S16, S25, S33, S35, S77, S92, S95, S99–S101, S105, S108, S113, S116, S118, S127, S132, S134, S142, S150, S151, Gamma ...... S18, S19, S34, S71, S72, S94, S195–S197, S155, S162, S168, S169, S174–S176, S208, S224–S228, S232, S236, S244, S245, S234, S244, S248, S318, S319, S321, S385, S386, S404 S249, S250, S271, S282, S285, S297, S298, S301, S303–S305, S319, S320, Gamma band activity ...... S195, S248 S344, S346–S349, S351–S355, S357–S359, S364, S372, S374, S397, S399–S401, Gamma oscillations ...... S34, S42, S72, S94, S195, S244, S248 S406, S417, S422, S425 Gating ...... S182, S183, S321, S324, S367, S446 GLT-1 ...... S188, S190, S191, S200, S214, S322 GDNF ...... S334, S414 Glucose ...... S53, S92, S102, S120, S121, S162, Gender ...... S2, S26, S46, S65, S69, S89, S116, S124, S169, S173, S174, S176, S208, S256, S257, S267, S270, S302, S354, S392, S413, S135–S138, S155, S156, S158, S160, S169, S179, S234, S236, S239, S241, S244, S415, S416, S445 S249, S251, S256, S259, S261, S265, S268, S271, S272, S275, S277, S298, S313, Glutamate ...... S6, S16, S17, S29, S34, S39, S46, S314, S324, S325, S352, S370, S371, S380, S388, S394, S396, S397, S399, S400, S50, S58, S59, S84, S88, S122, S133, S135, S136, S139, S140, S185, S188–S191, S402, S407, S422, S425, S426 S193, S200, S209, S214, S215, S229, S230, S259, S278, S295, S304, S305, Gene ...... S3–S5, S8, S10, S14, S15, S17, S21–S24, S312, S319, S320, S322, S325, S326, S333–S336, S338, S376, S381, S382, S384, S26, S27, S29, S31, S37–S40, S42, S43, S45, S46, S48, S49, S51, S52, S54, S55, S392, S430, S438, S440, S441, S445, S446 S61–S65, S71, S73, S77, S80, S82, S84, S85, S87, S89, S91, S92, S122–S128, Glutamine ...... S34, S278, S312, S381, S445 S130, S132, S133, S135, S146, S180, S181, S185, S198, S199, S207, S208, S210, Glycine ...... S8, S58, S59, S108, S187, S208, S304, S435, S436 S211, S213–S216, S235, S238, S239, S242, S245, S247, S253–S265, S268, S283, Glycine reuptake inhibitor (GRI) ...... S58 S284, S300, S301, S307, S312, S327, S330, S331, S335, S337, S342, S372–S381, S383, S385, S393, S397, S405, S445 Glycine reuptake inhibitor (gri) ...... S435 Gene CRHR1 ...... S125, S262, S378 Glycine uptake inhibitor ...... S108 Gene expression ...... S3, S8, S18, S19, S23, S26, S27, Glycopeptide ...... S312 S30, S31, S46, S50, S55, S60, S61, S71, S78, S85, S90–S92, S123, S128, Goal-directed behavior ...... S36, S270 S135, S138, S200, S202, S204, S208, S210, S213, S214, S219, S253, Gonadal steroid hormones ...... S267 S254, S257, S263, S265, S293, S333–S338, S341, S342, S372–S374, S378, S385, S409 GR ...... S23, S24, S85, S257, S284, S289, S373 Gene regulation ...... S55, S263, S374 Gray matter ...... S5, S10, S128, S135, S146, S148, S157, S172, S192, S268, S272, S278, S280, S281, S288, S377, S385, S387, S388, Gene therapy ...... S14 S392, S393, S396, S397 Gene variants ...... S15, S133, S255, S337, S379, S380 Grief ...... S358, S359, S407 Gene X environment ...... S5, S132 GRM ...... S382 Gene-environment interaction ...... S259 Growth factor ...... S22, S66, S90, S125, S202, S208 General population ...... S64, S95, S129, S175, S250, GSK3 ...... S56, S85, S86, S89, S90, S202, S203, S207, S307, S308 S252, S287, S301, S316, S334, S354, S371, S409 GWAS ...... S5, S23, S52, S61, S66, S130–S132, Generalized anxiety ...... S54, S137, S250, S351, S422 S135, S136, S263, S337, S380 Generalized anxiety disorder ...... S94, S111, S139, S141, S162, Gyrification ...... S147 S351, S422, S224–S226, S250, S302 Genes ...... S3, S4, S7, S14–S19, S21–S23, S26–S32, S37, S38, S40, S42, S44, S46–S48, S50–S52, S54, S55, S57, S61, S65, S70, S71, S77, S78, S80, S86, S91, S92, S122, S123, S126, S127, S130–S136, S138, S156, S157, H S177, S196, S198, S203, S204, S208, S210, S212, S213, S220, S239, S250, S251, S253–S255, S259–S265, S279, S293, S300, S327, S331, S334, S337, S338, S341, S342, S366, S368, S369, S372–S374, S376, S378, S380, S383, S385, S409, Habenula ...... S45, S118, S203, S448 S412, S434, S445 Hair follicle keratinocytes ...... S218 Genetic ...... S3–S5, S10–S12, S15, S18, S21–S24, S26–S31, Hallucinogen ...... S211 S38, S41, S42, S44–S49, S51, S52, S54–S57, S60–S66, S69–S71, S78, S80, S84– Haloperidol ...... S42, S103, S173, S184, S187, S274, S86, S89, S90, S123–S125, S128–S135, S147, S148, S164, S180, S186, S187, S198, S305, S335, S359, S382, S384, S436 S199, S202, S204, S206–S213, S217, S219, S220, S222, S232, S235, S237–S240, S245, S253–S255, S259–S262, S264–S266, S270–S272, S274, S277–S279, S283– HAM-A ...... S111, S140, S143, S224–S226, S351, S422 S285, S293–S295, S297, S301, S307, S308, S312, S315, S320, S321, S327, S333, Hap1 ...... S434 S338, S341, S366, S368–S370, S372–S381, S384, S387, S391, S398, S401, S405, HDAC ...... S44, S207, S341 S406, S409, S416, S421, S424, S425, S431, S434, S435, S437 HDAC6 ...... S85, S86 Genetic variation ...... S15, S42, S52, S54, S65, S126, S134, S135, S239, S240, S258, S262, S263, S279, S283, S284, S286, Health outcomes ...... S146, S287, S354, S396 S368, S373, S375–S379, S381, S397 Heart rate variability ...... S73, S386, S395, S410

ACNP 50th Annual Meeting Keyword index S493 Hemoglobin ...... S251, S388 Huntington’s disease GSK-3 HDACS transgenic mouse model . . . . . S207 Heritability ...... S61, S70, S78, S119, S130–S132, S198, S264, S375–S377 Hypopituitarism ...... S408, S409 High Resolution fMRI ...... S281 Hypothalamus ...... S7, S9, S10, S19, S55, S111, S119, High risk ...... S10, S11, S28–S29, S46, S50, S68–S69, S119, S158, S193, S203, S233, S234, S255, S258, S262, S266, S308, S315, S317, S337, S124, S135, S154, S215, S252, S259, S271–S272, S277–S278, S285, S297, S366, S400, S405, S432, S447 S371, S378, S390–S391, S398–S399, S401–S402, S407, S409 High throughput screening ...... S438 Highly active antiretroviral therapy ...... S305 I Hippocampus ...... S7, S8, S17, S18, S35, S38, S42, S45, S48, S57, S58, S60, S66, S73, S77, S78, S80, S82–S84, S86–S88, S119, S120, S126, S138, S140, S143, S144, S159, S161, S200, S201, S204, S205, S208, ICSS ...... S200, S201, S308, S432, S433 S209, S211, S212, S217, S223, S237, S238, S244, S246, S253–S255, S258, S266, IDO...... S88 S268, S272, S285, S286, S288, S295, S302, S303, S306, S307, S315, S319, S329, S335, S339, S364, S368, S373, S378, S383, S393, S395, S398, S402, S412, IL-18 ...... S317 S413, S430, S434, S444 Iloperidone ...... S102, S107, S135 Histamine ...... S185, S191, S198, S199, S224, S225, S260, S276 Imaging ...... S4, S10, S11, S18–S20, S22, S23, S28, S34, S36, S37, S45, S48, S51–S54, S58, S59, S67, S84, S87–S89, S93, S110– Histidine decarboxylase ...... S198 S112, S119, S151–S156, S165, S183, S204, S220–S222, S231, S239, S245, S261, Histone ...... S18, S27, S44, S86, S92, S123, S207, S263, S335, S341 S265–S268, S270, S271, S278, S281–S283, S289, S291, S292, S310, S336, S345, Histone phosphorylation ...... S92 S364, S368, S380, S381, S384, S386, S388, S389, S391, S393–S396, S399, HIV ...... S288, S305, S393 S400, S404, S408, S410, S418, S421, S436, S438, S445 Hiv infection ...... S288, S305 Imaging genetics ...... S22, S239 HMGB1 ...... S342 Imipramine ...... S85, S206 Hoarding ...... S226 Immediate early gene...... S184 Homeostasis ...... S9, S16, S21, S56, S80, S86, Immune system ...... S4, S30, S38–S40, S86–S88, S137, S138 S87, S89, S132, S189, S190, S196, S207, S212, S213, S227, S312, S354, S389, Impulse control disorder ...... S239, S250, S284, S308, S342, S343 S416, S448 Impulsive behavior ...... S21, S309, S313, S447 Hormone ...... S8–S10, S9, S11, S43, S55, S55, Impulsivity ...... S5, S78, S112, S113, S136, S137, S85, S126, S161, S166, S167, S172, S200, S201, S212, S217, S257, S258, S262, S139, S152, S154–S156, S175, S176, S199, S215, S235, S238, S239, S247, S262, S263, S268, S315, S354, S361, S362, S396, S407–S409, S429, S435 S270, S283, S286, S291, S309, S311, S316, S327, S343, S367, S368, S371, Hot flash ...... S317 S429, S446 HPA ...... S16, S43, S48, S138, S146, S161, S258, S262, Indo-trinidadians ...... S177, S178 S263, S315, S351, S378, S400, S405, S407, S409 Induced pluripotent stem cells ...... S218, S220, S292, S336 HPA axis ...... S16, S42, S43, S111, S138, S147, S159, Inducible pluripotent stem cells ...... S292 S161, S262, S315, S316, S351, S378, S406, S407, S410, S422 Infant development ...... S120, S163 HTR2C ...... S397, S398 Infection ...... S30, S31, S71, S137, S213, S218, S242, Human ...... S4, S5, S13–S15, S17, S20, S22–S24, S26–S28, S288, S303, S305, S336, S392, S448 S30, S32, S38, S40, S42, S43, S49, S53, S54, S57–S60, S63, S66, S71, S73, S74, S75, S78, S80–S82, S85, S86, S90, S95, S96, S117–S119, S123, S124, S126, Inferior frontal gyrus ...... S109, S150, S241, S248, S272, S387, S399 S127, S131, S137–S139, S141, S145, S147, S148, S153, S157, S158, S160, S173, Inflammation ...... S37, S39, S43, S49, S52, S86, S88, S178–S181, S183, S185, S188, S189, S192, S194–S196, S198, S200, S201, S205, S137, S269, S310, S348, S354, S414 S207, S208, S210, S211, S213, S215, S216, S218, S220, S221, S238, S253, S255, Inflammatory cytokines ...... S39, S86, S125, S138, S392, S414 S257–S261, S263, S274, S290, S293, S304, S305, S311–S313, S318, S320, Inhibition ...... S1, S8, S21, S32, S34, S36, S38, S324, S325, S333, S336–S338, S340–S342, S345, S361, S365–S367, S373, S376, S42–S44, S54, S55, S60, S67, S69, S71, S72, S75, S84–S86, S90, S380–S383, S390, S397, S411, S416, S417, S422, S428, S430, S433, S436, S437 S109, S112, S139, S142, S146, S158, S165, S166, S180, S183, S185, S188, Human brain ...... S3, S22, S23, S26, S32, S53, S61, S194, S203, S207, S209, S210, S230, S239, S256, S263, S276, S283, S286, S73, S76, S77, S154, S179, S180, S221, S256, S263, S264, S273, S275, S318, S292, S299, S302, S304, S307, S308, S319, S320, S322, S332, S334, S339, S336, S337, S375, S381, S382 S342, S344, S348, S375, S398, S405, S415, S416, S430, S433–S435, S438, Human cytomegalovirus ...... S336 S443, S448 Human laboratory studies ...... S428 Innate immunity receptor ...... S164 Human postmortem brain ...... S57 Inositol monophosphatase ...... S85, S430 Humans ...... S1, S4, S7, S9, S13, S14, S16–S18, S20, Insomnia ...... S15, S101, S102, S168, S185, S234, S302, S315, S353, S407 S22, S25, S30, S32, S36, S40, S44, S47, S49, S53, S54, S60, S66, S73, S74, S75, Insula ...... S47, S48, S58, S108–S110, S112, S76, S79, S80, S82–S84, S98, S117, S119, S126, S127, S142, S146, S148, S151, S119, S140, S144–S146, S151, S156, S178, S238, S242, S265, S266, S270, S277, S157–S159, S177, S185, S187, S193, S198, S200, S202, S203, S207–S211, S217, S283, S284, S288, S290, S319, S361, S364–S366, S368, S386–S389, S393, S231, S237, S239, S242, S243, S253, S257, S258, S267, S268, S274, S278, S282, S396, S399, S401, S403, S447 S288, S289, S304, S309, S313, S317, S318, S325–S327, S331, S340, S342, S354, S366, S372, S373, S375, S381, S392, S397, S398, S402–S404, S406, Insulin ...... S9, S10, S21, S66, S120, S121, S353 S426–S429, S431, S432, S439–S441 Insulin resistance ...... S9, S98, S174, S353 Huntington gene ...... S264 Integrins ...... S87, S260, S261

ACNP 50th Annual Meeting Keyword index S494 Interferon ...... S264, S300, S392 Light exposure ...... S315, S316 Interleukin-6 ...... S93, S202, S354 Liking ...... S178, S288, S367, S404, S428 Interneurons ...... S21, S31, S32, S71, S72, S195–S197, S212, S214, Linkage ...... S21, S51, S125, S133, S199, S210, S215, S259, S341, S366, S447 S263–S265, S283, S340, S376, S378, S380, S448 Interpeduncular nucleus ...... S373 Linkage analyses ...... S264, S265, S377 Intervention ...... S24, S43, S44, S64, S71, S83, S97, Lipid ...... S5, S57, S64, S101, S120, S121, S106, S107, S117, S119, S122, S129, S135, S143, S162–S165, S169, S215, S231, S174, S262, S302, S405, S429, S443 S238, S240, S242, S251, S253, S264, S272, S287, S298, S307, S352, S356, S359, Lisdexamfetamine ...... S100, S353 S366, S370, S371, S380, S394, S401, S415, S419–S421 Lithium ...... S65, S66, S85, S86, S90, S92, S114, Intravenous self-administration ...... S373, S442 S125, S128, S139, S146, S172, S181, S207, S208, S221, S249, S256, S263, S298, In-vivo ...... S34, S148, S243, S329, S385, S397 S300, S302, S303, S308, S332, S349, S354, S359, S391, S392, S400, S412, Iowa gambling task ...... S95, S175, S215, S239, S365 S418–S421, S423, S424, S430, S440, S441 IPSC ...... S42 Local field potentials ...... S18, S36, S196 Ipsc ...... S218, S293, S336 Locomotion...... S67, S82, S187, S207, S230, S255, S325, S435 IQ ...... S10, S70, S97, S106, S113, S116–S118, Locomotor activity ...... S6, S34, S50, S58, S75, S111, S123, S148, S153, S156, S239, S244, S246, S321, S399, S400, S419 S123, S152, S184, S185, S190, S191, S193, S200, S209, S214, S217, S258, S304, S310–S312, S316, S329, S333, S335, S375, S412, S432, S435 Iron deficiency ...... S251 Locus coeruleus ...... S56, S75, S80, S110, S440 Irritable bowel syndrome ...... S364 Long-acting injectable risperidone ...... S105 IRT ...... S369 Longitudinal ...... S5, S10, S11, S48, S69, S70, S73, S93, S105, S127, S147, S148, S156, S163, S238, S240, S244, S250, S261, S271–S274, S278, S281, S287, S297, S298, S345, S355, S357, S380, S386, S387, K S393, S399, S400, S409, S446 Longitudinal study ...... S145, S148, S160, S236, S240, S241, S244, S245, S283, S305, S315, S386, S390 Kappa opioid receptor ...... S77, S432, S440, S441 LTP ...... S1, S7, S8, S16, S36, S200, S201, S208, S312, S339, S447 KCNH2 ...... S210 Lupus ...... S447 Ketamine ...... S44, S45, S62, S63, S143, S195, Lurasidone ...... S99, S101, S127, S168–S170, S173, S174, S430, S436 S196, S205, S206, S214, S215, S278, S284, S294, S295, S299, S300, S326, S388, S410, S424 LY379268 ...... S278 Kinases ...... S21, S42, S56, S190, S328, S443 Lyme ...... S447 Kindling ...... S1 Lysergic acid diethylamide ...... S210, S212 Kinetics ...... S42, S72, S171, S287, S340, S436 Knockout ...... S17, S38, S41, S55–S57, S59, S71, S72, S80, S83–S85, S186, S187, S194, S198, S199, S206, S208, S258, M S308, S324, S325, S331, S333, S335, S340, S375, S406

Kynurenic acid ...... S38, S209 M1 receptors ...... S237 Kynurenine ...... S38, S209, S300 Macaque ...... S31, S148, S204, S373 Machine learning ...... S69, S130, S164 L MADRS ...... S101, S168, S173, S224, S225, S229, S300, S303, S344–S347, S351, S353, S356–S359, S395, S416, S418, S422, S423 Lamotrigine ...... S114, S278, S418–S420, S426 Magnetic ...... S47, S53, S123, S145, S151, S241, S280, Language ...... S10, S30, S37, S116, S120, S147, S363, S389, S393, S395, S399, S400, S411, S412, S424 S151, S157, S240, S272, S275, S358 Magnetic resonance imaging ...... S63, S121, S139, L-DOPA ...... S308 S142, S148, S155, S243, S293, S379, S393, S400, S418 Learned helplessness ...... S45, S83, S86, S432, S200–S203 Magnetic resonance spectroscopy ...... S34, S278, S312, S345, S381, S385, S390, S392, S417 Learning ...... S2, S11, S16–S19, S22, S35, S47, S54, S60, S66, S68, S71, S77, S83, S84, S95, S98, S106, S111, S114, S123, S126, Magnetic seizure therapy ...... S12, S230, S409 S131, S141, S143, S144, S147, S159, S164, S165, S171, S177, S193, S200, Major depression ...... S2, S15, S18, S28, S39, S201, S207, S215–S218, S223, S237, S242, S243, S264, S267, S274–S276, S42, S43, S45, S48, S49, S54, S69, S80, S87, S89, S93, S110, S118, S119, S125, S286, S296, S305, S308, S314, S318–S320, S325, S332, S364, S365, S393, S128, S146, S172, S200–S203, S205, S218–S221, S229, S251, S270, S272, S404, S448 S300–S302, S304, S328, S347, S359, S365, S386–S388, S390, S391, S395, Leptin ...... S9, S10, S97, S186, S262 S400, S413, S424, S432, S443 Level of response ...... S177, S326 Major depressive disorder ...... S3, S38, S44, S45, S68, S69, S88, S89, S91, S93, S94, S115, S118, S119, S124–S126, S136–S138, Levomilnacipran ...... S344, S345 S172, S201–S205, S222, S226, S229, S230, S250, S263, S296, S301–S304, Lhx6 ...... S384 S315, S343–S348, S350, S351, S353, S354, S356, S357, S386, S388, S389, S393, Life events ...... S137, S254, S288, S357 S394, S397, S398, S402, S413, S414, S417, S418, S422, S422, S431, S448

ACNP 50th Annual Meeting Keyword index S495 Maltreatment...... S148, S244, S406, S407 Metformin ...... S174 Mania ...... S69, S85, S92, S116, S123, S215, S216, Methadone ...... S427, S428 S238, S239, S298, S315, S343, S345, S349, S352–S354, S359, S388, S398–S400, Methamphetamine ...... S13, S14, S126, S180, S189, S402, S416, S419, S421, S426 S190, S217, S222, S289, S291, S319, S324, S325, S339, S340, S342, S375, S377, MAO AB knockout ...... S206 S380, S403, S405, S441, S442 Mao-A ...... S60, S285, S286, S348, S377, S397 Methodology ...... S12, S23, S26, S40, S100, S112, S120, S167, MAOI ...... S229, S298, S348 S220, S236, S255, S360, S416, S420 Marijuana ...... S316, S176–S179, S365–S368, S370, S380, S384 Methylation ...... S5, S18, S22–S24, S26, S27, S48, S73, S92, S123, S130, S254, S258, S297, S304, S307, S327, S356, S372, Marijuana use ...... S105, S176–S179, S301, S367 S417, S420 Mass spectrometry...... S166, S167, S443 Methylphenidate . . . . S19, S67, S75, S83, S113, S127, S153, S230, S286, S291 Maternal ...... S10, S17, S30, S55, S59, S60, S73, Mglu5 ...... S66 S74, S102, S109, S112, S118–S120, S145, S151, S159, S237, S238, S250, S251, S254, S258, S261, S295, S315, S336, S337, S361, S362, S377, S406 Mglur2 ...... S335, S382 MC4R ...... S65, S132 Mglur4 ...... S305, S306, S382 MDD ...... S3, S44, S45, S69, S87–S89, S91–S94, S110, Mglurs ...... S193, S326, S382 S117–S120, S124, S126, S138, S159, S201, S202, S204, S205, S222, S229, Mibampator ...... S227 S231, S258, S263, S296, S301–S303, S315, S343, S344, S346–S348, S351, S353, Mice ...... S2, S8, S9, S14–S16, S18, S21, S22, S30, S354, S356, S357, S383, S389–S391, S394–S396, S398, S400, S401, S414, S32, S34, S38–S43, S45, S54–S60, S67, S71, S72, S75–S89, S92, S94, S111, S417, S418, S422–S424, S432, S444 S123, S126, S127, S161, S182–S189, S191, S194–S197, S198–S200, S202–S219, MDL100907 ...... S282 S222, S223, S253, S258, S278, S305, S306, S308, S311–S313, S324, S325, MDMA ...... S282, S342, S427 S327, S329–S333, S335, S337, S338, S340, S342, S373–S375, S393, S412, S413, S430–S435, S437, S441, S443–S445 Medial prefrontal cortex ...... S18, S19, S34–S36, S62, S63, S82, S110, S113, S140, S144, S154, S182, S203, S211, S213, S289, Microarrays ...... S57, S78, S85, S91, S258 S311, S319, S320, S327, S362, S364, S366, S372, S374, S388, S395, S412, S435, Microdialysis ...... S6, S20, S47, S58, S81, S182, S185, S188, S442, S446 S191, S198, S209, S307, S310, S311, S323, S436 Medial visceromotor network ...... S395, S396 Microglia ...... S39, S40, S64, S86, S192, S336 Medication ...... S3, S7, S12, S13, S35, S38, S65, S87, Microrna ...... S77, S208, S293, S338 S90, S97, S99, S102–S106, S118, S122, S133, S135, S136, S151, S153, S160, S161, Midbrain...... S9, S20, S28, S35, S47, S78, S85, S164, S167–S169, S173–S175, S179–S181, S189, S195, S221, S225, S226, S228, S87, S88, S119, S198, S238, S266, S268, S286, S291, S318, S319, S364, S380, S232, S233, S235, S245, S247, S249, S251, S266, S272–S274, S277, S279, S285, S397, S409, S441 S286, S290, S292, S297, S301, S305, S344, S347, S349, S351, S352, S354, S357, S360, S368, S371, S383, S387, S389, S390, S392, S397, S400, S405, S420, Migration ...... S31, S32, S49, S89, S208, S222, S260, S341 S422–S428, S434, S442 Mild cognitive impairment ...... S52, S236 Meditation ...... S264 Mindfulness ...... S162, S163 Medium spiny neurons ...... S67 Minority ...... S36, S121, S300, S355, S370 MEG ...... S5, S32, S240, S247, S318, S321 Mirna ...... S293, S338, S339, S374 Meg ...... S365, S386 Mismatch negativity ...... S33, S34, S134, S169 Melatonin receptors ...... S217 Mitochondria ...... S220, S221 Memory ...... S1–S4, S6, S16–S19, S22, S33, S35, S36, Mixed state ...... S420 S41, S44, S49, S63, S66, S67, S71, S76, S77, S80, S82, S84, S85, S98, S99, MK-801 ...... S8, S182, S183, S214, S304 S104, S106, S107, S114, S116–S119, S123, S131, S134, S141, S143, S159, S171, S172, S177, S182, S184, S185, S200, S207, S209, S211, S217, S218, S223, Modafinil ...... S66, S67, S177 S235–S237, S245, S253–S256, S264, S270, S272, S274–S276, S278, S285, Model ...... S3, S4, S6, S9, S13–S18, S21, S305, S308, S309, S313, S316, S318, S320, S339, S350, S364, S365, S393, S399, S22, S24–S26, S30, S31, S33, S34, S39, S40, S43–S45, S47, S48, S50, S53–S56, S402, S404–S406, S408, S411, S412, S415, S423, S437 S58, S60, S61, S66, S70, S72, S73, S76–S78, S80, S81, S83–S85, S87–S90, Menopause ...... S93, S200, S268, S317, S408 S92, S96, S97, S99, S101, S104–S106, S111, S113, S116, S117, S127, S130, S133– S135, S143–S146, S148, S151, S153, S156–S158, S164, S168, S174, S178, S179, Mesolimbic ...... S7, S28, S92, S107, S178, S179, S181, S184–S189, S191, S192, S195, S196, S198–S216, S218, S222–S225, S227, S209, S322, S323, S333, S334, S363, S378, S404, S444, S449 S229, S230, S234, S235, S237–S239, S243, S246, S252, S253, S256, S259, S263, Meta-analysis ...... S57, S104, S115, S132, S147, S265, S266, S270, S271, S276–S279, S282, S294, S296, S298, S304–S308, S150, S151, S168, S170, S176, S231, S242, S356, S359 S311, S315, S317, S320, S322, S324–S327, S330, S332, S334, S336, S339–S341, Metabolic effects ...... S121, S162, S174, S439 S344, S345, S354, S357, S364–S366, S369, S372, S373, S376, S377, S383–S386, Metabolic syndrome . . . . S24, S97, S98, S132, S175, S302, S352, S354, S425 S389, S391, S392, S398, S399, S401, S403, S404, S409, S411, S425, S427, S429–S433, S436–S439, S441, S444, S448 Metabolism ...... S21, S39, S48, S53, S64, S80, S88, S92, S97, S98, S120, S121, S161, S162, S180–S182, S208, S232, S233, S241, Moderators ...... S3, S104, S355, S379, S380, S395 S242, S256, S257, S262, S267, S270, S278, S289, S301, S309, S331, S345, Monkey ...... S13, S48, S53, S146, S148, S386, S392, S399, S408, S413, S415, S435, S442, S448 S149, S204, S219, S231, S318, S340, S409, S436 Metabolism FKBP5 gene ...... S256, S262 Monoamine Oxidase a ...... S285, S298, S397 Metabolomics ...... S24 Monoamines ...... S173, S182, S206, S218, S319 Metacognitive ...... S246 Monozygotic twins ...... S148, S256

ACNP 50th Annual Meeting Keyword index S496 Mood ...... S15, S16, S19, S38, S44, S45, Negative symptoms ...... S20, S33, S34, S40, S48, S49, S54, S55, S57, S68–S70, S73, S82, S85–S87, S90, S92, S41, S72, S97–S99, S105–S108, S135, S171, S176, S185, S187, S195, S221, S232, S114, S119, S125, S132, S137, S142, S153, S161–S163, S176, S200, S224, S225, S245, S368, S369, S440 S239, S251, S252, S259, S265, S282, S285, S288, S290, S298, S315, S317, S318, Negative Symptoms of Schizophrenia . . . S100, S108, S171, S183, S213, S233 S343, S347, S349, S350, S354, S355, S357, S359, S370, S372, S379, S388, S390, Neopterin ...... S300 S393, S396, S399, S400, S404, S417–S422, S426, S427, S430–S432, S448 Network ...... S2, S10, S12, S15, S22, S23, S24, S28, S32, S44, S45, Mood disorders ...... S15, S21, S22, S38, S55, S51–S53, S61, S69, S72, S85, S88, S110, S112, S113, S115, S119, S120, S123, S57, S59, S61, S67–S70, S80, S86, S89, S90, S92, S93, S110, S125, S126, S128, S130, S136, S143–S146, S148–S151, S154–S156, S161, S175, S195, S196, S203, S135, S138, S163, S200, S201, S204, S205, S219, S221, S238, S253, S302, S314, S208, S213, S218, S221, S236, S241, S245, S247, S255, S259, S260, S270–S273, S315, S336, S357, S376, S383, S390, S393, S397, S398, S448 S275, S276, S280, S282, S284, S285, S290, S294, S299, S310, S318–S320, Morphine ...... S36, S50, S81, S167, S311, S312, S331, S332 S335, S337, S338, S341, S354, S356, S361–S363, S365–S368, S374, S376, S381, Motion ...... S68, S149, S153, S154, S201, S248, S268, S271, S386, S387, S389, S391, S395–S397, S399, S409, S412, S416, S425, S447 S289, S391, S402, S413 Neurogenesis ...... S16, S38, S39, S67, S85, S87, Motivation ...... S7, S9, S19, S28, S36, S41, S112, S89, S161, S339, S341, S342, S374, S412, S434 S118, S119, S158, S190, S193, S194, S199, S200, S205, S238, S239, S241, S266, Network analysis ...... S46, S61, S274, S282, S396, S397 S267, S339, S393, S403, S404, S440 Neural stem cell transplantation ...... S341 Motor ...... S6, S31, S50, S55, S75, S112–S114, S118, Neuregulin ...... S208, S278, S374 S120,S130,S134,S137,S154,S156,S165,S166,S178,S184,S190,S200,S203,S207, S227, S232, S239, S240, S242, S271, S284, S290–S292, S305, S306, S308, S311, Neuroactive steroids ...... S390 S319, S321, S324, S333, S343, S361, S367, S386, S391, S397, S410, S411, S416, S432 Neuroanatomy ...... S6, S148, S394, S400 Mouse ...... S5, S8, S13, S15, S17, S18, S22, Neurocognition ...... S40, S118, S147, S170, S239, S294, S305 S29–S31, S34, S39, S40, S43–S46, S54–S56, S60, S71, S72, S75, S76, S81, Neurodegeneration ...... S207, S257, S305, S342, S393 S83–S87, S92, S127, S183, S188, S194, S196, S199, S200, S202, S205–S208, S211, S212, S214–S217, S253, S306–S308, S311, S327, S329, S340, S342, S373, Neurodevelopment ...... S26, S42, S78, S135, S145, S374, S393, S430, S437, S443 S147–S149, S209, S213, S219, S240, S261, S279, S320, S336, S337, S394 Movement ...... S44, S69, S80, S95, S99, S156, Neurodevelopmental ...... S5, S10, S11, S21, S27, S169, S174, S212, S216, S268, S281, S311, S319, S385, S386, S408, S431, S447 S29–S32, S46, S49, S50, S59, S70, S84, S123, S128, S129, S148, S156, S187, S198, S213, S218, S237, S238, S240, S259, S260, S275, S279, S320, S327, Movement disorder ...... S95, S96, S169 S336, S337 mPFC ...... S18, S19, S34–S36, S60, S62, S63, Neuroeconomics ...... S366 S71, S74, S82, S110, S154, S165, S182, S211–S213, S311, S315, S327, S329, S362, S364, S366, S372, S374, S433, S436, S446 Neurofeedback ...... S164, S165 MRI . . . . .S3–S6, S10, S23, S28, S33, S36, S41, S48, S49, S53, S63, S68, S69, Neurogenesis ...... S16, S38, S39, S67, S85, S87, S89, S161, S91, S119, S121, S139, S141, S142, S144, S146, S148–S151, S154, S156, S158, S339, S341, S342, S374, S412, S413, S435 S165, S174, S243, S244, S264, S266, S268, S269, S271, S272, S274, S276, Neuroimaging ...... S4–S6, S10, S15, S21, S23, S29, S37, S41, S48, S49, S277, S280–S283, S286, S293, S302, S303, S318, S320, S363, S379, S381, S385, S51–S53, S69, S73, S91, S92, S108–S110, S112–S114, S119, S129, S142, S148, S387, S390, S394–S396, S398, S402, S413, S418 S152, S155, S158, S162, S163, S192, S203, S267, S268, S274, S278, S280, S289, MRS ...... S5, S10, S25, S34, S35, S136, S277, S278, S385, S390, S391, S417 S295, S318, S381, S384, S389, S391–S394, S398 MST ...... S230, S231, S410 Neuroinflammation ...... S268, S279, S342 mTBI ...... S267, S268, S408, S408 Neuromodulation ...... S165, S386 MTHFR ...... S97, S98, S232, S233, S245 Neuropeptide S ...... S193 Mu ...... S38, S126, S311, S375 Neuropeptide Y ...... S32, S57, S132, S172, S204, S212, S262, S378 Muscarinic ...... S62, S67, S181, S236, S422 Neuropeptides ...... S9, S11, S72, S193, S212, S216, S361, S433 Myelin ...... S166, S192, S243, S269, S278, S333, S336 Neurophysiology ...... S6, S231, S314, S389, S410 Myelination ...... S6, S147, S157, S278, S336 Neuropsychiatric disorders ...... S10, S12, S25, S26, S40, S46, S56, S60, S66, S67, S70, S71, S83, S133, S138, S139, S143, S145, Myosin ...... S339 S195, S198, S207, S212, S216–S218, S228, S238, S255, S276, S284, S292, S294, S319, S416, S438 N Neuropsychiatric symptoms ...... S227, S281, S409, S448 Neuropsychology ...... S4, S5, S11, S95, S96, S107, S112, S113, S116, S118, S131, S134, S152, S171, S227, S237, S238, S247, S265, N170 ...... S248 S272, S274, S292, S293, S305, S351, S386, S409, S415 N250 ...... S248 Neuroregulin ...... S7, S208, S279, S374, S375 NAA ...... S139, S140, S277–S278 Neuropsychological assessment ...... S96, S386 N-acetylaspartate ...... S139, S277 Neurosteroid ...... S81, S306, S307, S341 Naltrexone ...... S114, S178, S180, S181, Neurotensin ...... S190 S186, S235, S301, S342, S367, S426–S427, S438 Neurotrophins ...... S86, S202, S338 Narp ...... S412, S413 Next generation sequencing ...... S26, S46, S61, S123, NDEL1 ...... S219 S125, S131, S213, S222, S263, S372, S374 NDST3 ...... S132 NF-kB ...... S19 Near-miss ...... S309, S310 NGF ...... S124

ACNP 50th Annual Meeting Keyword index S497 Nicotine ...... S6, S9, S13, S50, S51, S67, S95, S98, Offspring ...... S30, S31, S68, S69, S79, S102, S120, S151, S164–S166, S179, S189, S191, S221, S235, S237, S243, S277, S284, S285, S132, S145, S151, S163, S202, S209, S213, S222, S237, S238, S250, S251, S261, S287, S289, S290, S326, S332–S334, S368, S372–S375, S378–S381, S403, S315, S320, S327, S336, S337, S361, S389, S391 S404, S427, S439 Olanzapine ...... S22, S58, S65, S105, S107, S120, Nicotine dependence ...... S13, S50, S165, S189, S277, S121, S127, S128, S133, S170, S173, S175, S176, S184, S186, S187, S205, S275, S284, S285, S291, S332, S333, S373–S375, S378–S380, S428 S352, S384, S424, S434, S438 Nicotine withdrawal ...... S179, S180, S243, S368, S373–S375, S405 Oleoylethanolamide ...... S383 Nicotine-seeking ...... S326, S332 Olfaction ...... S440 Nicotinic ...... S67, S97, S98, S106, S107, S171, S179, Oligodendrocyte ...... S333, S336 S182, S183, S185, S191, S199, S326, S368, S372, S373, S378–S380, S403 Omega-3 fatty acids ...... S413 Nicotinic acetylcholine receptor ...... S41, S97, Open field ...... S38, S75, S80, S83, S126, S127, S106, S183, S372, S373, S375 S164, S187, S200, S209, S215, S333, S335, S416, S434, S441 Nicotinic receptors ...... S179, S191, S209 Operant ...... S79, S189–S191, S193, S211, S313, NK1 antagonist: Aprepitant:: ...... S427 S323, S324, S325, S339, S363, S429 NMDA ...... S7, S8, S16, S34, S35, S44, S45, S58, Opioid ...... S7, S36, S47, S166, S167, S178, S186, S71, S72, S187, S189, S190, S194, S205, S209, S283, S295, S299, S304, S326, S235, S311, S312, S317, S318, S367, S370, S371, S375, S376, S392, S393, S427, S329, S338, S382, S435, S438 S428, S439, S441, S443 NMDA antagonist ...... S62, S190, S214, S215, S295, S304 Opioid dependence ...... S367, S427 NMDA receptor ...... S7, S8, S16, S17, S34, S45, S58, S62, S72, S84, S88, Opioid withdrawal ...... S427, S428 S187, S189, S195, S196, S208, S283, S284, S305, S329, S381, S382, S384, Opioids ...... S36, S37, S167, S206, S310, S367, S435, S437 S370, S371, S375, S376, S392, S393 NMDA receptor antagonist ...... S44, S58, S195, S196, S205, S283 OPRM1 ...... S180, S181, S235, S254, S375, S376 nNOS ...... S219 Optogenetics ...... S45, S92, S196, S444 Nociceptin ...... S234 Orbitofrontal ...... S35, S79, S83, S152, S154, Nonhuman primates ...... S148, S231, S326, S439 S158, S241, S315, S319, S364, S365, S403 Nonmedical prescription opioid use ...... S370 Orbitofrontal cortex ...... S27, S35, S75, S79, S82, S91, Noradrenaline ...... S79, S182, S224, S225 S126, S154, S155, S266, S276, S290, S377, S388, S405 Noradrenergic ...... S6, S7, S76, S80, S81, Orexin ...... S9, S194, S233, S234, S317, S433, S434 S83, S111, S143, S180, S284, S309, S441 Organic cation transporters ...... S430 Norepinephrine ...... S6, S7, S21, S60, S75–S77, S80, Oscillation...... S32, S71, S72, S94, S157, S81, S83, S153, S180, S187, S194, S205, S276, S286, S302, S310, S328, S331, S195, S196, S248, S271, S385, S400, S448 S332, S339, S340, S344, S346, S374, S422, S431, S441, S442, S448 Outcome ...... S2, S3, S7, S11, S12, S20, S28, S34, S35, Nosology...... S2 S43, S52, S58, S73, S75, S84, S94, S97–S100, S104, S105, S106, S108, S113, Novel object recognition ...... S72, S152, S182, S209, S210, S431, S437 S115, S120, S121, S122, S133–S135, S140, S146, S148, S151, S161, S162–S164, S167, S168, S170, S172, S175, S176, S178, S179, S181, S186, S209, S210, S223, Novel P3 ...... S245 S226, S231, S233, S235, S238, S241, S242, S251, S262, S267, S275, S278, S299, Novelty seeking ...... S126, S127, S327, S377 S303, S309, S314, S327, S336, S342–S345, S348, S350, S351–S355, S357, NPY ...... S132, S133, S172, S173, S204, S213, S261, S378 S358–S361, S367, S369, S378, S381, S394, S395, S398, S399, S400, S405, S407, S410, S414, S415, S417, S419–S421, S424, S426–S428, S430 NRXN1 ...... S29, S260, S337 Oxcarbazepine ...... S359 Nucleus accumbens ...... S6, S13, S19, S36, S47, S49, S56, S67, S73, S78, S79, S82, S84, S90, S107, S112, S119, S126, S145, Oxidation ...... S57, S445 S146, S166, S174, S179, S184, S185, S188, S190, S191, S202–S204, S209, S214, Oxidative stress ...... S57, S93, S214, S342, S345, S374, S435, S444, S445 S238, S242, S254, S258, S265–S267, S287, S289, S291, S292, S311, S312, S317, Oxygen ...... S238, S289, S342, S345, S395, S400, S415, S424, S444, S445 S322, S325, S328, S329, S331, S333–S335, S337, S338, S340, S361, S363, S380, S382, S391, S397, S404, S412, S433, S442, S446 Oxytocin ...... S72, S73, S96, S160, S161, S166, S255, S361, S406, S408, S421, S422, S428, S439, S448 NVHL ...... S56, S211

O P

Obesity ...... S95, S121, S137, S158, S159, S237, P2...... S245, S295 S251, S261, S262, S266, S267, S291, S354, S416, S444, S8–S10, S12, S39, S47, S52 P3b ...... S245 Obsessive compulsive disorder ...... S1, S28, S40, S54, S75, PACAP ...... S23, S257, S258 S79, S108, S136, S144, S216, S226, S229, S249, S255, S282, S294, S321 Pain ...... S36, S37, S124, S125, S137, S159, Occupancy ...... S13, S24, S58, S59, S173, S174, S179, S167, S227, S235, S297, S310, S311, S317, S318, S345, S350, S359, S364, S375, S180, S183, S206, S435, S436, S438 S386, S392, S393, S397, S432, S433, S448 OCD ...... S40, S75, S76, S79, S108, S109, S136, S141, Paliperidone extended-release ...... S102 S144, S145, S226, S229, S249, S250, S255, S294, S295 Palmitoylethanolamide ...... S383

ACNP 50th Annual Meeting Keyword index S498 PANSS ...... S49, S95–S97, S99–S103, Pharmacotherapy ...... S7, S12, S14, S79, S106–S108, S133, S135, S136, S169–S175, S232, S233, S246, S272, S274, S84, S163, S178, S186, S189, S212, S218, S226, S294, S297, S310, S311, S322, S277, S280, S294, S415, S424 S352, S354, S412, S426, S428, S430 Parent training ...... S228 Phase 2B clinical trial ...... S133 Parental ...... S55, S78, S102, S113, S148, S158, Phencyclidine ...... S58, S182, S187, S188, S212, S431, S437 S159, S252, S258, S265, S277, S362, S407 Phenomenology ...... S198, S265, S314 Parkinsonism ...... S102, S414 Phenotype ...... S13, S17, S21, S26, S27, Parkinson’s disease ...... S25, S26, S70, S94, S29, S52, S59, S64–S66, S71, S73, S77, S78, S81, S82, S85, S90, S92, S123, S116, S117, S286, S292, S297, S305, S308, S319, S343, S414 S125, S130, S131, S161, S198, S201–S205, S207, S213, S214, S238, S253, S256, Paroxetine ...... S120, S225, S226, S346, S351, S434, S435 S266, S279, S312, S329, S330, S368, S369, S378, S383, S387, S432, S443, S444, S448 Partial agonist ...... S171, S179, S181–S183, S185, S186, S192, S224, S225, S303, S357, S368, S375, S381, S382, S437 PHNO ...... S13, S158, S198, S268, S269 Partial deletion ...... S156 Phosphodiesterase ...... S223, S322, S433 Parvalbumin ...... S21, S32, S42, S72, S94, Phronotype ...... S394 S196, S204, S205, S212, S219, S385 Physical activity ...... S97, S98, S251, S339 Paternal age ...... S70, S102, S250 Physiology ...... S18, S23, S42, S53, S55, S59, Pathological gambling ...... S28, S297, S309, S342 S60, S67, S71, S172, S182, S187, S197, S200, S201, S217, S279, S312, S321, S324, S405, S407, S439, S441, S447 Pathology ...... S5, S8, S17, S31, S40, S42–S44, S59, S66, S81, S88, S92, S116, S123, S153, S154, S161, S205, S207, S209, S218, Pioglitazone ...... S354 S219, S227, S277, S292, S308, S309, S337, S342, S363, S381, S390, S393, PKA ...... S221, S328, S338, S340 S408, S432, S446 Place conditioning ...... S50, S440 Pathway ...... S7, S16–S19, S22, S23, S31, S38, Placebo ...... S7, S12, S14, S19, S37, S44, S39, S44–S46, S48, S52, S56, S57, S59, S61, S62, S64, S65, S88–S91, S110, S49, S62, S94–S104, S106–S108, S113, S118, S133, S147, S159, S161, S130, S186, S187, S204, S208, S214, S216, S217, S221–S223, S230, S234, S162, S169–S171, S173, S177–S181, S186, S195, S224–S227, S229–S235, S258–S261, S277, S283, S305, S328, S333, S334, S337, S339, S340, S363, S372, S237, S276, S283, S284, S286, S287, S290, S291, S296, S297, S299–S301, S374, S375, S393, S401, S434, S435, S443, S446 S303, S309, S317, S318, S342–S346, S348–S353, S356–S359, S364, S365, PDE ...... S223, S337, S338, S432 S368, S375, S379, S382, S385, S404, S409, S417–S424, S426–S429, P-CREB ...... S328, S335 S436, S440 Pediatric ...... S30, S60, S65, S83, S121, Placebo-controlled ...... S24, S62, S95, S100, S123, S141, S147, S151, S163, S265, S296, S311, S349, S350, S387, S388, S391, S103, S104, S107, S108, S127, S128, S161, S162, S168, S173, S180, S342, S394, S400 S344–S346, S348–S351, S353, S354, S356, S357, S360, S368, S378, S380, S417, S421, S422, S425–S428, S224–S227, S229, S230, S233, S234, S276, S283, Pediatric bipolar ...... S5, S152 S299, S301, S303 Pediatric bipolar disorder ...... S5, S112, S252, S253, S349 Plasticity ...... S16–S19, S35, S38, S40, Pediatrics ...... S77, S137, S240 S55, S56, S59, S63, S66, S76, S81, S85, S89, S135, S139, S146, S172, S217, Peptide ...... S29, S32, S43, S166, S185, S223, S248, S325, S334, S338, S339, S341, S374, S391, S410, S434, S440, S191, S212, S258, S266, S311, S422, S430, S432, S433, S441, S448 S446–S448 Perceptual integration ...... S32 Play behavior ...... S151, S443, S448 Perinatal ...... S214, S215, S390 PMDD ...... S127 Peritraumatic dissociation ...... S142 PMS ...... S127 P-ERK ...... S186, S328 Polymorphism ...... S21, S22, S26, S29, S38, Personality ...... S39, S130, S139, S238, S262, S46, S52, S71, S80, S125–S127, S135, S149, S180, S209, S238, S239, S247, S263, S270, S288, S296, S315, S371, S372, S375–S377, S379, S386, S253, S257, S258, S279, S284, S297, S301, S380, S383 S429, S430 Polypharmacy ...... S168, S352 Pervasive developmental disorders ...... S228 Polysomnography ...... S196, S314 PET ...... S9, S13, S19, S20, S25, S48, S58, Positive allosteric modulator ...... S58, S81, S97, S106, S227, S230, S305 S59, S63, S142, S154, S155, S161, S162, S174, S179, S180, S198, Positron Emission Tomography ...... S20, S48, S63, S142, S158, S221, S265, S266, S270, S271, S276, S280, S282, S285, S287–S292, S317, S161, S179, S198, S221, S256, S265–S268, S280, S282, S285, S291, S319, S379, S318, S363, S379, S381, S384, S386, S393, S397, S402–S404, S413, S436, S386, S392, S393, S397, S402, S403, S413, S438 S437, S447 Post traumatic stress disorder ...... S80 PET neuroimaging ...... S317 Posterior cingulate...... S4, S51, S110, S119, PFC ...... S6, S18, S21, S27, S36, S41, S42, S140, S145, S150, S154, S246, S265, S267, S268, S271, S284, S285, S318, S319, S48, S61–S63, S72, S82, S110, S120, S138, S140, S147, S185, S187, S188, S193, S362, S364, S365, S368, S408 S194, S200, S209, S211, S213, S219, S238, S270, S289, S295, S325, S328, S333, Postmenopausal ...... S93, S317, S408 S337, S366, S368, S383–S385, S388, S399, S443, S444 Postmortem ...... S8, S27, S34, S35, S42, S53, S57, Ph ...... S26, S61, S62, S72, S82, S87, S89, S182, S61, S83, S87, S89–S93, S132, S135, S138, S157, S184, S187, S202, S204, S205, S193, S221, S233, S234, S310, S345, S355, S382, S384 S214, S218, S220, S221, S240, S257, S333, S337, S378, S381, S382, S384, S385 Pharmacogenetics ...... S64, S122, S180, S181, S320 Postmortem brain ...... S17, S86, S91, S92, S137, Pharmacokinetics ...... S14, S206, S404, S442 S138, S210, S221, S222, S432, S434

ACNP 50th Annual Meeting Keyword index S499 Postnatal ...... S10, S17, S21, S30, S32, S50, S59, Prodromal...... S10, S129, S226, S227, S240, S241, S245, S271, S272, S383 S60, S78, S83, S84, S120, S123, S145, S148, S151, S163, S183, S188, S194, Prodrome ...... S100, S128, S241, S242 S209, S213–S215, S219, S220, S222, S253, S295, S316, S337, S431, Prodrug ...... S133, S199, S200, S320 S443, S447 Prognostic grouping ...... S419 Postpartum ...... S148, S200, S347, S390, S397 Programming ...... S315, S336 Postpartum depression ...... S390, S397 Progressive change ...... S10, S281 Posttraumatic stress ...... S17, S256, S407 Propentofylline ...... S322 Posttraumatic stress disorder ...... S1, S7, S24, S76, S78, S111, S140, S142, S143, S257, S267, S296, S313, S314 Proteomics ...... S24 Postural sway ...... S292 Psychiatry ...... S1, S2, S5, S10, S25, S47–S49, S53, S65, S67, S76, S77, S85, S87, S93, S104, S113, S115, S126, S129, Power spectral analysis ...... S196, S234, S314 S132–S134, S136, S137, S141–S143, S146, S152, S154, S156, S159, S160, S162, PPI ...... S34, S69, S72, S75, S76, S110, S131, S134, S163, S165, S166, S172, S176, S191, S197, S199, S206, S214, S216, S218, S219, S169, S170, S184, S198, S199, S213, S214, S240, S254, S255, S259, S264, S265, S221, S225, S226, S229, S230, S236, S240–S243, S248, S249, S251, S255, S334, S448 S258, S262, S265, S266, S270, S276, S277, S280, S282–S285, S290, S295, Prader-Willi syndrome...... S266, S267 S296, S298, S299, S302, S303, S312, S317, S327, S338, S341, S342, S344, S349, Pramipexole ...... S184, S308, S309 S355, S356, S359, S365, S375, S377, S378, S390, S391, S394, S396–S398, S400, S402, S410, S417–S421, S427, S431, S434, S444 Prazosin ...... S6, S7, S332 Psychometrics ...... S417 Pre-mild cognitive impairment ...... S236 Psychomotor ...... S118, S123, S243, S320, S420, S442 Preclinical ...... S7, S13, S24, S25, S36, S37, S40, S41, S43, S59, S66, S89, S98, S107, S126, S182, S189, S191, S192, S201, S230, Psychopathology ...... S5, S18, S24, S49, S56, S258, S268, S284, S287, S297, S306, S311, S312, S317, S324, S325, S342, S379, S78, S81, S95, S105, S106, S109, S110, S112, S119, S121, S126, S129, S384, S397, S402, S405, S411, S427, S432, S435, S436, S438 S134–S136, S141, S148, S162, S168, S172, S176, S201, S204, S238, S244, S246, S249, S250, S257, S258, S265, S266, S272, S280, S294, S383, Prediction ...... S7, S11, S27, S31, S35, S47, S91, S384, S407 S126, S130, S154, S287, S310, S327, S365, S381 Psychophysiology ...... S141, S406 Prefrontal ...... S3, S5, S7, S15, S16, S20–S23, S26–S28, S32, S34–S36, S42, S44, S45, S50, S53–S55, S57, S61–S63, S68, Psychosis ...... S10, S11, S17, S41, S49, S94, S69, S72, S77, S82–S84, S89, S109, S110, S112, S114, S115, S119, S123, S95, S98, S100, S101, S103, S104, S106, S117, S129, S130, S135, S172, S135, S138, S140, S142, S145, S147, S148, S150, S152, S154, S157, S165, S169, S208, S210, S212, S221, S240, S241, S245–S248, S271, S272, S275, S278, S182, S184, S185, S187, S192–S196, S200, S203, S204, S209, S213, S215, S281, S294, S337, S338, S368, S369, S383, S394, S396, S409, S412, S219, S220, S223, S236, S238, S243, S245, S247, S253, S255, S266, S269, S437, S442 S270, S273–S277, S279, S281, S282, S285, S286, S290, S295, S297, S298, Psychostimulant ...... S13, S75, S180, S327, S307, S311, S313, S315, S318–S321, S325, S327–S329, S333, S337, S340, S365, S339, S340, S342, S375, S441, S442 S366, S381, S384–S388, S391, S396–S400, S402, S403, S411, S436, S440, Psychotherapy ...... S23, S24, S76, S110, S136, S445, S448 S159, S162, S166, S172, S257, S265, S402 Pregnancy ...... S10, S59, S60, S120, S145, S151, Psychotic ...... S2, S3, S11, S17, S25, S49, S68, S96, S98, S163, S237, S238, S251, S261, S315, S327, S347, S390 S105, S106, S108, S113, S114, S129, S157, S172, S174, S214, S221, S222, S227, Pregnenolone ...... S306, S307 S240, S245, S246, S250, S251, S271, S272, S276, S278, S281, S294, S348, Prelimbic ...... S35, S50, S54, S83, S84, S194, S440 S383, S384, S400, S401, S409, S410, S412, S437, S438 Pre-mild cognitive impairment ...... S236 Psychotic depression ...... S412 Prenatal ...... S26, S27, S70, S120, S145, S148, PTSD ...... S1, S11, S12, S17, S18, S23, S24, S48, S49, S151, S152, S220, S222, S251, S315, S327, S336 S54–S56, S76, S78–S84, S110, S111, S140, S142–S144, S162, S163, S172, S203, S256, S257, S259, S267, S268, S296, S306, S307, S313, S314, S359, S395, Prenatal cortisol ...... S145 S407–S409, S445–S447 Preparation ...... S26, S167, S247, S271, S272, Puberty ...... S146, S200, S219, S406, S407 S394, S398, S407, S408, S430, S445 Punishment ...... S215, S267, S365 Pre-pregnancy BMI ...... S238 Putamen ...... S19, S28, S47, S112, S115, S126, Prepulse inhibition ...... S21, S34, S72, S75, S76, S98, S141, S150, S158, S174, S268, S269, S284, S286, S291, S292, S341, S391, S394, S131, S134, S169, S184, S198, S213, S214, S240, S243, S264, S334, S434, S446 S397, S401, S403, S414, S415 Prevalence ...... S9, S18, S30, S55, S56, S75, S83, S116, S122, S129, S150, S155, S158, S175, S193, S211, S250–S252, S255, S288, S309, S315, S343, S360, S370, S371, S378, S397, S408, S409, S416, S420, S425, S428 Q Prevention ...... S11, S18, S24, S38, S63, S64, S69, S78, S86, S112, S129, S139, S144–S146, S161, S162, S191, S230, S236, S240, S256, S257, S261–S264, S296, S305, S317, S347, S357, S371, S380, S392, S394, S407, S426, S437, S442 QTL ...... S65, S375 Primary insomnia ...... S233, S234 Quetiapine ...... S65, S98, S99, S105, S127, S128, Primates ...... S13, S48, S53, S83, S87, S145, S148, S170, S172, S173, S175, S176, S184, S274, S302, S343, S354, S425 S318, S342, S364, S373, S376, S415 Quetiapine XR ...... S99, S101, S170, S173, S343, S344 Prison ...... S262 Quinpirole ...... S13, S50, S51, S309, S310, S366

ACNP 50th Annual Meeting Keyword index S500 R S165, S166, S174, S176–S179, S181–S185, S187, S191, S192, S196, S197, S199, S201–S206, S209, S211, S212, S216, S224–S226, S228, S230, S231, S235, Rac1 ...... S434 S239, S242, S246–S248, S250, S251, S253, S254, S257, S262–S264, S266, S269–S272, S276, S278–S280, S282–S284, S286, S287, S289–S291, Radioimmunoassay ...... S110, S139, S166, S167 S295–S298, S300–S304, S307, S309, S312, S315–S319, S321, S322, S325–S331, Randomized controlled trial ...... S162, S163, S175, S375, S425 S335–S340, S343–S346, S348, S349, S352–S357, S361–S367, S369, S373–S375, Rapid antidepressant ...... S16, S44, S45, S62, S295, S299, S444 S378, S380, S382, S384, S386, S392, S395, S401–S407, S409–S413, S415–S417, S422–S426, S430–S432, S436, S438, S443, S446, S447, S448 Rapid tryptophan depletion ...... S76, S136 Response control ...... S112 Rat ...... S1, S6, S9, S13–S19, S22, S35–S37, S44, S47, S50, S53, S55, S56, S58, S62, S66, S68, S73, S75, S76, S78, S78–S81, Response inhibition ...... S3, S50, S54, S55, S66, S83, S84, S87, S107, S151, S152, S159, S167, S182–S191, S193, S204, S108, S109, S112, S123, S158, S283, S284, S286, S366 S199–S201, S203–S205, S209–S216, S230, S254, S274, S287, S289, S295, Resting state ...... S110, S148, S149, S154, S265, S270, S305–S314, S316, S317, S319, S320, S322–S334, S336–S342, S363, S366, S271, S400 S372–S374, S382, S392, S422, S430–S440, S442–S444, S446–S448 Resting state connectivity ...... S33 Rater training ...... S231 Resting State fMRI...... S148, S150, S157, S270, S277, S398 RCT ...... S105, S106, S173, S304, S417, S418 Resting state functional connectivity ...... S148, S149, S238, S270, S277 Receptor ...... S6–S9, S13, S16, S17, S19–S21, S23, S24, S29, S30, S34, Reuptake...... S19, S45, S58, S75, S79, S80, S82, S37–S46, S49, S50, S53–S55, S58, S59, S62, S65, S67, S70, S71, S73, S76, S79, S83, S87, S120, S122, S124, S139, S143, S187, S188, S201, S205, S206, S225, S81–S83, S85–S88, S90, S97, S98, S107, S122, S124–S126, S132–S134, S157, S226, S253, S265, S266, S284, S294, S296, S297, S302, S307, S310, S311, S314, S159, S164, S166, S171, S178–S187, S189–S195, S199, S200, S204, S208, S210, S344, S346, S357, S384, S417, S430, S431, S434, S443, S447 S211, S216–S219, S224, S225, S233–S235, S237, S254, S256–S263, S266, S268, S269, S274, S276, S279, S280, S283, S284, S286, S291, S292, S295, S302, S304, Reward ...... S6, S9, S15, S19, S20, S27, S28, S305, S307–S312, S317, S319, S327–S339, S342, S357, S364, S366, S373, S375, S35, S36, S41, S47, S48, S52, S68, S81, S82, S92, S95, S112, S115, S126, S139, S378–S380, S382, S383, S392, S393, S397, S402, S403, S405, S406, S409, S415, S145, S164, S165, S179, S190, S191, S193, S196, S197, S200, S201, S215–S217, S427, S428, S431, S432, S434–S436, S438–S441, S443, S448 S239, S242, S261, S265, S267, S272, S273, S289–S291, S308–S310, S312, S316, S321, S322, S324, S328, S331, S334, S336, S339, S363, S364, S367, S375, S380, Receptor reserve ...... S181, S182 S391, S405, S415, S416, S427, S429, S433, S441–S444 Recruitment ...... S12, S28, S70, S87, S163, Reward deficiency ...... S291, S292 S166, S186, S187, S216, S349, S360, S366, S387, S404, S413 Reward processing ...... S41, S49, S112, Recurrent depression ...... S229 S146, S165, S179, S205, S272, S273, S289–S291, S440 Regulation ...... S3, S15–S19, S21, S23, S24, Rhesus ...... S13, S31, S48, S146, S148, S42, S45, S48, S49, S55, S57–S59, S68, S69, S73, S77, S82, S84, S86, S87, S189, S192, S204, S231, S288, S319, S326, S340, S373, S436 S89, S92, S94, S109–S111, S113, S119, S135, S140, S142, S144, S148, S153, S158, S160, S163–S166, S178, S184, S190, S194–S196, S202, S204, S211, S212, S214, Rhesus macaques ...... S321, S326, S364, S373 S233, S234, S257, S262, S270, S290, S293, S307, S315, S318, S321, S325, S327, Right inferior frontal gyrus ...... S149, S255, S388, S391, S392 S333, S336, S339, S341, S372, S374, S385, S390, S392, S400–S402, S405, Riluzole ...... S44, S139, S140, S229, S299, S300 S406, S410, S418, S422, S430, S434, S443, S445, S448, S449 Rimonabant ...... S95 Reinforcement ...... S7, S9, S13, S28, S36, S79, S83, S126, S189, S192, S211, S215–S217, S242, S286, S325, S328, Risk ...... S4, S9–S11, S14, S20, S22–S27, S29, S30, S40, S42, S43, S330–S332, S338, S339, S364, S365, S372–S374, S380, S442, S448 S45, S48–S52, S54, S60–S64, S66, S68–S71, S73, S78, S90, S93, S95, S97, S98, S101, S102, S104, S105, S109, S111, S112, S118–S123, S125, S126, Reinstatement ...... S6, S13–S15, S36, S50, S81, S179, S129–S133, S135–S137, S141, S142, S145, S148, S151, S156, S160, S161, S163, S190, S191, S193, S194, S211, S312, S322, S326–S328, S330–S332, S339, S363, S166, S168, S175–S179, S185, S195, S198, S200–S202, S204, S208–S211, S215, S440, S441 S216, S222, S230, S232, S233, S237, S238, S240–S242, S245, S246, Rejection...... S112, S392, S393 S250–S252, S254, S257, S258, S260–S265, S267, S271–S274, S277–S279, Relapse ...... S6, S7, S13–S15, S20, S35, S36, S283, S285, S290, S291, S297, S298, S300, S301, S307, S310, S314–S317, S326, S65, S76, S101, S102, S105, S106, S162, S165, S166, S178, S179, S188, S189, S337, S349, S355, S357, S359, S366–S373, S375, S377, S380, S381, S383, S384, S211, S230, S265, S284, S285, S289, S290, S300, S306, S311, S315, S322, S387, S390, S391, S396, S398, S401, S402, S404, S405, S407–S410, S420, S326–S329, S331, S339, S347, S357, S374, S377–S379, S403, S405, S412, S420, S425, S434, S437, S439, S441, S443–S448 S442, S443 Risk behavior ...... S366 Relapse prevention ...... S101, S377 Risk factors ...... S23, S24, S28, S44, S49, S63, S69, Remission ...... S62, S119, S166, S168, S172, S176, S70, S119, S121, S129, S137, S175, S219, S222, S237, S251, S283, S315, S341, S201, S205, S225, S229, S239, S245, S246, S252, S297, S298, S300–S304, S368, S370, S371, S377, S425, S427 S315, S347, S352, S353, S356, S357, S381, S394, S411, S412, S417, S419–S424, Risk-taking ...... S49, S50, S92, S145, S215, S432, S434 S238, S267, S308, S316, S367, S393 Reproduction ...... S248 Risperidone ...... S34, S58, S65, S72, S98, S105, Residual symptoms ...... S265, S351, S421 S120, S121, S167, S170, S172, S173, S175, S176, S187, S228, S258, S275, S382, Resilience ...... S4, S11, S23, S24, S48, S54, S56, S425, S435, S439 S82, S85, S200, S201, S203, S204, S257, S327, S363 Risperidone long-acting injection ...... S167 Response ...... S1, S3–S5, S7, S8, S12, S13, S15, Ritalin ...... S75 S18, S19, S22–S24, S28, S33, S35, S37–S39, S41, S43, S45, S47, S48, S52, Rivastigmine ...... S223, S224, S236 S53, S55–S57, S59, S62–S66, S69, S73, S75–S77, S79–S84, S86–S88, S93–S95, S101–S103, S105, S106, S108–S115, S119, S121, S123–S126, S132, S133, RNA sequencing ...... S26, S336, S374 S135–S137, S139–S141, S143–S145, S147, S151–S153, S159, S160, S162, S163, Rna-seq ...... S55, S212, S213, S373, S378

ACNP 50th Annual Meeting Keyword index S501 Rodent ...... S14, S23, S36, S38, S58, S59, Serotonin transporter ...... S60, S83, S86, S132, S76, S80, S92, S107, S151, S172, S200, S212, S215, S216, S288, S289, S304, S142, S146, S206, S260, S265, S266, S282, S340, S377 S309, S311, S327, S334, S382, S416, S437, S438 SERT ...... S4, S60, S83, S86, S131, S206, S260, S282, S376, S422, S430 Romantic love ...... S406 Set shifting ...... S75, S83, S182, S187, S188, S214, S215, S319, S320 Rtms...... S232, S362, S363, S413 Severe ...... S24, S54, S95, S105, S106, RT-PCR ...... S8, S88, S91, S210, S334, S337, S342, S373, S383 S112–S114, S121, S127, S128, S149, S153, S166, S172, S204, S228–S230, S232, S235, S250, S255, S266, S277, S295, S299, S310, S313, S320, S348, S357–S359, S369, S384, S385, S387, S403, S407, S414, S420, S422, S425, S429, S444 S Severe mood dysregulation ...... S116, S153, S387 Sex ...... S6, S14, S20, S23, S26, S55, S56, S70, S87, S105, S113, S122, S128, S145, S148, S156, S161, S176, S177, S215, Satiety ...... S19, S158, S179, S266, S297, S308, S363 S221, S238, S241, S254, S255, S257, S264, S265, S271, S277, S279, S280, S313– SBSS ...... S82 S316, S337, S357, S359, S362, S366, S369, S376, S378, S381, S384, S385, S389, S391, S393, S398, S413, S428 Schizoaffective disorder ...... S40, S94, S96, S97, S104–S106, S132, S173–S175, S195, S368, S382, S424 Sex difference ...... S6, S55, S275 Schizophrenia ...... S5, S7, S8, S10, S11, S17, Sexual dysfunction ...... S121, S146, S302, S407, S422 S18, S20–S36, S39–S42, S48, S49, S51, S56–S62, S66, S67, S70–S73, S76, SFRP3 ...... S89 S77, S84, S89, S94–S108, S113, S116, S117, S123, S126, S128–S136, S139, S143, Side effect ...... S85, S122, S132, S135, S187, S307, S311, S312 S146, S147, S157, S162, S163, S168–S176, S182–S185, S187, S188, S195, S196, S199, S208–S215, S218–S222, S232, S233, S238, S240–S251, S253–S256, S260, Signal ...... S19, S21, S26–S28, S34, S54, S263–S265, S270–S281, S284, S292–S294, S303, S317, S319–S321, S336, S55, S73, S75, S86, S97, S106, S109, S112, S118, S140–S142, S144, S154, S165, S337, S344, S362, S368, S371, S375, S381–S386, S394, S395, S400, S406, S179, S183, S186, S199, S203, S230, S234, S239, S244, S247, S248, S267, S409–S411, S415–S418, S424, S431, S433–S438, S444, S446 S270, S271, S273, S276, S281, S288–S291, S310, S315, S321, S364, S365, S390, S393–S395, S400, S401, S404, S415, S423, S424, S448 Schizotypal personality disorder ...... S269 Signal detection ...... S94, S95, S231, S360, S361 Scopolamine ...... S62, S423, S422, S435 Signal transduction ...... S56, S186, S187, S253, S320, S340, S443 Screening ...... S37, S56, S90, S100, S107, S128, S129, S153, S161, S163, S170, S186, S198, S207, S220, S224, S225, S230, Signalling ...... S16, S35, S213, S272, S310 S232, S252, S263, S285, S287, S288, S291, S303, S310, S353, S357, S369, S394, Sign-trackers ...... S199 S408, S437 Simulations ...... S61, S72, S181, S194, S226, S227, S410 Secondary prevention ...... S24, S306 Sk channels ...... S329 Second-generation antipsychotic ...... S34, S114, S184, S382 Sleep...... S11, S15, S16, S44, S45, S71, S93, S94, Sedation ...... S181, S180, S183, S184, S290, S324, S403, S422, S428 S125, S178, S195, S212, S223, S233, S234, S251, S252, S301, S314–S316, S324, Segmentation ...... S145, S149, S156, S390, S394 S330, S362, S389, S390, S392, S430, S445, S446 Seizure ...... S56, S200, S208, S230, S231, Sleep apnea ...... S251 S329, S386, S399, S400, S410, S411, S413 Sleep deprivation ...... S15, S16, S212, S223, S362 Seizure threshold ...... S85, S386, S410–S412 Sleep EEG ...... S44, S195, S234, S314 Selegiline transdermal system ...... S229, S230, S348 Sleep loss ...... S16, S223 Self-administration ...... S6, S35, S50, S81, Sleepiness ...... S98, S99, S315, S391, S392 S178, S189–S194, S211, S216, S311, S322, S324, S325, S327–S330, S332–S334, Slow-wave activity ...... S212 S338, S339, S342, S365, S372–S374, S429, S430, S441, S442 Smoking ...... S6, S13, S20, S26, S50, S93, Self-awareness ...... S245, S246 S98, S151, S164, S165, S175, S176, S178–S180, S243, S251, S277, S284, S285, Self-compassion ...... S162 S287, S290, S326, S368, S374, S375, S377–S380, S403–S405, S428 Self-report ...... S49, S137, S149, S158, S163, Smoking cessation ...... S98, S176, S179, S287, S165, S181, S225, S241, S249, S250, S256, S259, S263, S288, S291, S294, S316, S289, S332, S374, S375, S379–S381, S405, S428 S351, S367, S371, S376, S386, S416, S429 Smoking cue ...... S165 Semantic priming ...... S279 Smoking cue reactivity ...... S285 Sensitization ...... S50, S54, S76, S159, S164, SNP ...... S15, S21–S23, S29, S42, S46, S51, S52, S169, S191, S217, S308, S330, S334, S384 S61, S65, S122, S126, S130–S133, S135, S136, S180, S222, S238, S239, S253, Sensorimotor gating ...... S76, S79, S169 S255–S259, S262, S263, S265, S283, S284, S293, S337, S368, S369, S373, Sensory gating ...... S98, S198, S240 S375–S380, S383 Serine racemase ...... S208, S214 SNRI ...... S205, S226, S344 Serotonin ...... S19, S45, S56, S59, S60, S62, Social vocational outcome ...... S104 S76, S79, S82, S83, S85–S88, S118, S120, S122, S124, S125, S128, S130, S132, Sociability ...... S307, S318, S427 S133, S136, S139, S182, S184, S189, S201, S202, S205, S206, S210, S224, S225, Social ...... S2, S3, S5, S11, S30, S34, S48, S253, S265, S266, S282, S294, S297, S306, S307, S311, S314, S319, S326, S329, S49, S72–S74, S77, S82, S85, S86, S90, S96, S105, S106, S109, S110, S335, S344, S346, S357, S374, S376, S397, S409, S417, S422, S430, S431, S434, S112, S115, S117, S137, S146–S148, S150–S152, S161, S163, S168, S172, S435, S442, S447, S448 S178, S179, S190, S194, S196, S198, S201, S224, S225, S228, S241–S243, Serotonin 2C receptor ...... S310 S246, S249, S259, S272, S276, S280, S289, S294, S306, S308, Serotonin syndrome ...... S206 S316, S318, S329, S341, S342, S351, S355, S357, S359, S377, S390, S392,

ACNP 50th Annual Meeting Keyword index S502 S393, S406, S407, S409, S410, S416, S422, S427–S429, S439, S440, S443, S377, S378, S384, S396–S398, S405–S410, S412, S415, S433, S441, S443, S444, S448 S446, S448 Social anhedonia ...... S241, S242 Stress response ...... S23, S56, S77, S80, Social anxiety ...... S144, S225, S241, S242, S270, S272, S405, S406 S87, S142, S147, S160, S258, S287, S306, S314, S315, S336, S363, S409, S442 Social anxiety disorder ...... S73, S108, S111, S225, S392, S421 Striatum ...... S9, S10, S19, S20, S28, S47, S52, S68, S75, S82, S84, S109, S112, S115, S145, S150, S152, S154, S155, S161, Social behavior ...... S72, S73, S96, S112, S196, S318, S405 S192, S199, S206, S207, S213, S216, S238, S258, S264, S267, S271, S272, S285, Social cognition ...... S6, S33, S34, S96, S117, S147, S286, S289–S291, S305, S306, S310, S311, S319, S329, S338–S340, S362, S365, S171, S271, S318, S362, S440 S379, S384, S386, S391, S393, S397, S398, S403, S405, S415, S416, S448 Social defeat ...... S43, S82, S85, S90, S161, S201, S202, Stroop ...... S53, S54, S111, S114, S158, S164, S271, S286, S305, S395 S328, S329, S431, S433, S444 Structural imaging ...... S23, S267, S387, S391, S394 Social evaluation ...... S112 Structural MRI ...... S3, S31, S48, S172, Social interaction ...... S82, S112, S152, S160, S202, S240, S270, S277, S279, S318, S379, S381, S399 S225, S256, S258, S260, S341, S444 Structure ...... S2, S6, S10, S21, S23, S37, S40, Social isolation ...... S81, S88, S258, S443 S48, S53, S64, S68, S78, S79, S84, S87, S134, S156, S157, S162, S197, S198, Social phobia ...... S110, S111, S141, S225, S250 S199, S208, S216, S217, S234, S235, S244, S249, S260, S264, S273–S278, S281, S322, S327, S362, S368, S387, S399, S400, S430, S449 Social stress ...... S49, S82, S147, S160, S202, S328, S329, S409 Subgenual ...... S53, S109, S112, S141, S283, S319, S386, S391, S396 Social withdrawal ...... S97, S213, S232 Subgenual cingulate ...... S161, S318, S396, S400, S401 Sodium ...... S308, S418, S445 Subjective cognitive impairment ...... S236 Somatosensory ...... S71, S146, S147, S321 Subjective effects ...... S6, S178, S180, S203, S211, S288, S404, S427, S428 Somatostatin ...... S32, S57, S205, S212, S385 Substance abuse ...... S51, S67, S81, S116, Sox6 ...... S384 S148, S157, S158, S176, S211, S239, S249, S270, S283, S301, S366, S367, S369– Spatial navigation ...... S268 S371, S393, S427, S437, S447 Spatial processing ...... S6, S131, S264 Substance P ...... S138, S180, S216 SPECT ...... S20, S231, S386, S399, S398 Substantia nigra ...... S10, S130, S158, S190, Spines ...... S62, S63, S217, S218, S221 S199, S203, S258, S269, S281, S291, S305, S329, S402 SRI ...... S32, S79, S288, S436 Subsyndromal comorbid manic symptoms ...... S418–S420 SSR1419415 ...... S351 Subthalamic nucleus ...... S171, S343 SSRI . . . . .S60, S62, S86, S87, S117, S119, S118, S122, S125, S163, S201, S205, Subtyping ...... S280 S225, S265, S294–S297, S304, S306, S307, S313, S314, S346, S347, S408, Sucrose ...... S9, S19, S38, S47, S48, S197, S200, S413, S416, S425, S429, S430 S203, S325, S330, S367, S412, S440–S442, S444 SSRT ...... S75 Suicidality ...... S98, S172, S300, S359, S420 Startle ...... S1, S34, S41, S54, S76–S78, S98, Suicide ...... S26, S27, S89, S99, S130, S131, S142, S169, S184, S214, S215, S243, S258, S334, S406, S407, S446, S137–S139, S144, S146, S160, S161, S166, S172, S239, S256, S257, S262, S447, S449 S263, S269, S296, S300, S357–S359, S365, S371, S389, S413, S419, S422, S425, Startle response ...... S215, S240, S406, S407, S448 S446 Statistical analysis ...... S51, S91, S116, S146, S153, S157, S289, S314, Suicide attempt ...... S130, S139, S262, S357, S359, S365, S371, S423 S345, S361 Suicide intent ...... S160, S161, S359 Steady state ...... S173, S177, S195, S295, S321, S436 Superior longitudinal fasciculus ...... S147, S157, S244, S399 Stem cells ...... S218, S220, S292, S336, S341 Surface area ...... S148, S158 Stereotypy ...... S184, S198, S199, S333 Susceptibility ...... S10, S21, S43, S46, S56, STG ...... S150, S154, S157, S240, S241, S365 S61, S63, S70, S71, S84, S86, S113, S124, S126, S132, S134, S145, S198, S201, Stimulant ...... S7, S13, S82, S192, S285, S375, S202, S208, S210, S213, S238, S250, S251, S260, S274, S283, S327, S336–S338, S377, S378, S380, S426, S427, S432, S442 S375, S395, S404, S445 Stopping ...... S219, S321, S322 Sustained attention ...... S75, S98, S123, S152, S160, S177, S199, S215 Suvorexant ...... S233, S234 Strain ...... S54, S75, S77, S81, S205, S213–S216, S327, S334, S340, S448 Strategies ...... S10, S14, S20, S36, S39, S54, Sweet taste test ...... S366 S57, S59, S64–S66, S68, S129, S159, S162, S165, S166, S168, S185, S187, S191, Switching ...... S42, S156, S168, S175, S228, S322, S356, S417, S425, S448 S193, S197, S201, S213, S231, S239, S262, S270, S276, S278, S287, S290, S306, Synapse ...... S30, S39, S40, S62, S68, S84, S317, S335, S343, S346, S356, S360, S380, S384, S394, S397, S405, S407, S414, S88, S221, S293, S319, S325, S338, S341 S421, S438, S448 Synapsin ...... S62, S372, S439, S445 Strattera ...... S83 Synaptic plasticity ...... S7, S16, S39, S40, Stress ...... S1, S5, S7, S10, S12, S16, S19, S44, S62, S67, S77, S81, S184, S212, S213, S268, S325, S329, S338, S341, S372, S21–S24, S28, S37–S39, S43, S49, S54–S57, S59, S60, S62, S63, S73, S76–S83, S374, S412, S438, S443, S447, S448 S85–S88, S90, S110, S111, S119, S126, S127, S137, S144–S150, S159–S161, S172, Synaptogenesis ...... S17, S30, S44, S62, S63, S78, S210, S337 S178, S184, S193, S194, S200–S205, S213, S214, S222, S243, S249, S254, S256–S259, S262–S264, S287, S288, S295, S296, S302, S306, S307, S315, Synthetic cathinone ...... S440, S441 S318, S327–S329, S331, S332, S336, S337, S341, S351, S354, S357, S364, S369, System XC ...... S190, S319, S320

ACNP 50th Annual Meeting Keyword index S503 T Traumatic brain injury ...... S56, S115, S267, S268, S291, S292, S407 Treatment ...... S2, S3, S5–S7, S9, S11, S13, S14, S16, S18, S22–S25, S28, S30, S35, S38–S40, S44, S48, S50, S52, TAAR1 ...... S339, S340, S435, S436, S440 S55, S57, S58, S60, S64–S66, S69, S70, S73, S75, S77–S79, S82–S86, Tail-suspension ...... S205, S310, S432 S88–S92, S94–S108, S110, S111, S114–S116, S118, S120–S122, S124, S125, S127–S129, S132, S133, S135, S136, S138–S140, S143, S145, S151–S153, S159, Tamper resistant formulations ...... S166 S161–S180, S182–S185, S187–S194, S199–S210, S212–S215, S217, S220, Tat ...... S392 S223–S235, S237, S241–S243, S247, S250–S253, S260, S261, S265–S267, TBI ...... S43, S268, S269, S291, S292, S407, S408 S269, S272, S274–S276, S281, S284, S289, S290, S294–S308, S310, S312– S314, S317, S319, S321–S323, S325, S327, S329–S332, S334–S336, S338, S340, TC-5619 ...... S98 S341, S343–S360, S366, S367, S369, S371, S372, S374–S376, S378–S380, Temperament ...... S78, S109, S112, S204, S256 S382, S384–S387, S390–S396, S399, S401–S403, S405, S409, S411–S415, Temperature ...... S181, S206, S317, S430, S442, S449 S417–S428, S430–S441, S443, S444, S448 Testosterone ...... S55, S257, S315, S324, S386, S408 Treatment prediction ...... S394 TG2 ...... S433 Treatment resistance ...... S39 Thalamus ...... S20, S51, S58, S126, S145, Treatment resistant ...... S34, S37, S39, S72, S166, S172 S146, S150, S157, S158, S161, S162, S174, S180, S203, S238, S246, S258, S266, Treatment resistant depression ...... S12, S18, S37, S39, S267, S278, S286, S288, S318, S340, S345, S364, S365, S393, S394, S403, S65, S90, S121, S205, S356, S386 S415, S416, S448 Treatment response ...... S3, S23, S65, S102, Therapeutics ...... S12, S17, S36, S37, S43, S105, S110, S117, S121, S133, S139, S140, S159, S164, S221, S246, S265, S297, S53, S76, S98, S106, S107, S127, S168, S176, S201, S211, S216, S298, S301, S302, S304, S343, S352, S386, S387, S402, S418, S423, S424, S218, S219, S228, S230, S240, S242, S247, S253, S257, S259, S270, S426, S431 S276, S286, S291, S297, S304, S311, S325, S340, S344, S348–S350, Treatment-seeking alcoholics ...... S283, S371 S379, S380, S382, S393, S394, S414, S416, S417, S421, S434, S438, S443, S446, S447 Treatments ...... S1, S2, S4, S5, S11, S12, S14, S15, S25, S40, S41, S43, S52, S59, S63, S66, S69, S79, S95, Thyroid hormone ...... S161, S441 S96, S99, S100, S104, S107, S109, S118, S122, S126, S128, S132, Time estimation ...... S379 S140, S164, S170, S175, S176, S180, S185, S191, S194, S198, S200, S201, Timing ...... S7, S41, S55, S62, S163, S210, S211, S321 S210, S215, S217, S225, S231, S232, S234, S238, S253, S261, S266, S276, TLR ...... S342 S285, S290, S294, S297, S299, S302, S304, S308, S309, S312, S313, S324, S331, S342, S345, S346, S349, S350, S354, S360, S381, S386, S393, TLR4 ...... S164, S342 S394, S399, S402, S411, S412, S415, S418, S422, S424, S425, S431–S434, TMS ...... S27, S232, S362, S363, S413 S439, S447 Tobacco ...... S6, S7, S50, S98, Treatment-seeking alcoholics ...... S283 S99, S164, S179, S180, S191, S251, S287, S326, S332, S369, S372, S379, Trka ...... S124 S380, S404 Trkb ...... S45, S124, S208, S258, S433 Tobacco addiction ...... S175, S176, S332, S372, S373 TRP channel ...... S447, S448 Tolerance ...... S14, S76, S121, S178, S184, S208, S215, S308, S324, S326 TRPV1 ...... S309, S310 Top-down control ...... S199, S209, S285 Tryptophan ...... S38, S60, S76, S135, S136, S209, S300 Topiramate ...... S114, S342, S343, S404 Tryptophan hydroxylase ...... S127 Tourette syndrome ...... S198, S232, S254, S259, S268 TTC12 ...... S377 Toxoplasma gondii ...... S242 Tyramine ...... S298 Trace amines...... S435, S440 Tramadol ...... S37, S206 U Transcranial magnetic stimulation ...... S165, S232, S362 Transcription ...... S2, S15, S19, S23, U99194 ...... S183 S27, S59, S62, S71, S86, S132, S135, S202, S207, S222, S254, S263, S264, S293, S305, S307, S325, S331, S336–S338, S342, S373, S374, S385 Unaffected siblings ...... S90, S122, S123, S278, S279, S400, S401 Trans-generational ...... S202 Unconscious ...... S403 Transgenic mouse ...... S13, S43, S64, S207, S217, S257, S305 Unemployment ...... S166, S368, S369 Transient ...... S17, S50, S66, S73, S83, Up-states ...... S194 S88, S108, S120, S195, S197, S203, S216, S227, S253, S299, S310, S318, S319, V S321, S325, S339, S446, S449 Translational science ...... S12, S25 Transporter ...... S9, S19, S21, S39, S80, V1b receptor ...... S351 S83, S85, S86, S108, S188, S190, S197, S200, S211, S224, S225, S282, S307, Val66met ...... S127, S149 S338–S340, S344, S384, S430, S435 Val66Met ...... S253 Trauma ...... S1, S11, S24, S48, S49, S54, Validation ...... S11, S20, S22, S24, S25, S76, S78, S82, S111, S140, S142, S149, S250, S256, S257, S263, S287, S288, S31, S37, S51, S66, S98, S131, S133, S159, S167, S193, S202, S212, S213, S222, S296, S314, S371, S408–S410 S252, S253, S259, S293, S346, S385, S417, S421

ACNP 50th Annual Meeting Keyword index S504 Valproate ...... S207, S349, S359, S422, S423 W Varenicline ...... S97, S98, S179, S368, S374 Variability ...... S4, S5, S11, S20, S27, S54, S58, S65, Wanting ...... S28, S365, S366 S72, S85, S93, S110, S111, S112, S132, S138, S152, S172, S176, S221, S227, S231, S238, WeightS47, S65, S101–S103, S107, S121, S132, S133, S136, S148, S158, S167–S169, S239, S263, S267, S270, S290, S292, S314, S360, S375, S390, S395, S409, S410, S173–S176, S186, S200, S201, S220, S228, S261, S265, S266, S268, S291, S418, S434 S297, S303, S311, S312, S326, S329, S350, S393, S425, S428, S439, S441 Vascular disease ...... S250 Weight gain ...... S9, S64, S65, S72, S88, S103, S107, S121, S132, S133, S158, S169, S173, S174, S176, S186, S291, Vasopressin ...... S138, S151, S166, S351, S361, S408 S297, S302, S303, S329, S349, S350, S428, S439, S440 Velocardiofacial syndrome ...... S270 Weight loss ...... S88, S174, S266 Venlafaxine ...... S3, S226, S296 White matter ...... S5, S10, S32, S34, S37, S68, S91, S146–S149, S152–S154, Venous plasma nicotine ...... S404 S156, S192, S222, S243, S244, S268, S272, S275, S277, S278, S280–S282, S288, S336, S362, S390, S393, S394, S396–S399, S401 Ventral hippocampus...... S211 Widespread pain ...... S235 Ventral striatum ...... S28, S48, S115, S155, S157, S177, S216, S238, S239, S266, S272, S276, S277, S285, S287, S289, Williams syndrome ...... S73, S156 S290, S291, S365, S379, S387, S392, S395, S402, S404 Withdrawal ...... S19, S47, S50, S94, S96, S100, S111, , S176, S179, S188, Ventral tegmental area ...... S6, S9, S15, S192, S194, S204, S213, S217, S228, S232, S285, S289, S296, S305, S306, S313, S19, S36, S73, S75, S78, S92, S164, S192, S197, S203, S205, S272, S316, S322, S324, S329, S331–S334, S340, S341, S350, S366, S368, S369, S372– S305, S325, S327, S330, S332, S337, S340, S396, S431, S434, S437, S441, S374, S409, S426, S427 S444, S448 Women ...... S7, S9, S10, S31, S47, S48, Ventromedial prefrontal cortex ...... S48, S141, S143, S164, S271, S55, S93, S120, S128, S130, S135, S140, S142, S145, S146, S159, S162, S163, S365, S368 S196, S200, S201, S235, S236, S255, S261, S266, S268, S275, S284, S285, S288, S297, S298, S313–S317, S328, S347, S371, S378, S390, S396, S397, S404, Veteran ...... S23, S96, S100, S110, S111, S406, S408, S415, S422, S426–S428 S131, S140, S143, S162, S163, S247, S248, S256, S265, S267, S268, S284, S295, Working memory ...... S3, S5, S6, S10, S313, S355, S367, S381, S408, S446 S21–S23, S32–S35, S49, S71, S72, S98, S106, S107, S114, S117, S118, S123, VGlut ...... S203 S134, S135, S147, S152, S156, S171, S172, S174, S177, S209, S210, S215, S236, Vilazodone ...... S357 S237, S248, S270, S274, S276, S277, S279, S281, S286, S313, S320, S351, S362, S363, S366, S423, S424, S434 Violence ...... S122, S139, S160, S371, S441 Working model of the child interview ...... S118 Viral load ...... S304, S305 Viral vector ...... S9, S14, S19, S331, S432 VMAT1 ...... S211, S212 X Voltammetry ...... S73, S363 Volunteers ...... S37, S41, S58, S67, S98, X-linked ...... S46, S134 S144, S149, S158, S160, S169, S177, S180, S235, S244, S246, S254, S267, S269, S276, S279, S290, S293, S296, S299, S317, S383, S387, S392, S395, S398, S401, S413, S427, S428, S436 Y Voxel based morphometry ...... S28, S391, S393 VTA ...... S6, S15, S36, S73, S78, S92, S164, Yohimbine ...... S76, S193, S253, S308, S309, S317 S196, S197, S203, S272, S309, S322, S325, S327, S328, S330–S332, S334, S431–S433, S440, S442, S443 Z Vulnerability ...... S4, S10–S12, S15, S19, S21, S23, S24, S41, S48–S50, S69, S82, S83, S85, S95, S109, S123–S125, S130, S144, S149, S157, S176, S206, S211, S238, S244, S250, Zebrafish ...... S198, S207 S254, S257, S261, S271, S274, S278, S279, S284, S287, S288, S308, S314, S315, S327, S328, S330, S331, S333, S337, S339, S376, S377, S383, S384, S391, S392, Ziprasidone ...... S65, S105, S127, S175, S184, S255, S422 S410, S440, S441 ZNF804...... S337, S338, S368

ACNP 50th Annual Meeting