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Ciências Da Saúde: Ensino, Formação E Pesquisa Ciências da saúde: ensino, formação e pesquisa Organizadores: Yasmin da Silva Santos, Fernanda Ferreira Evangelista, Fernanda de Oliveira Bottino, Arthur Daniel Rocha Alves, Tiago Savignon, Tainah da Silva Galdino de Paula Editora Amplla Campina Grande, 2020 2021 - Editora Amplla Copyright © Editora Amplla Editor Chefe: Leonardo Pereira Tavares Design da Capa: Editora Amplla Projeto Gráfico e Editoração: Higor Costa de Brito Ciências da saúde: ensino, formação e pesquisa está licenciado sob CC BY 4.0. Esta licença exige que as reutilizações deem crédito aos criadores. Ele permite que os reutilizadores distribuam, remixem, adaptem e construam o material em qualquer meio ou formato, mesmo para fins comerciais. O conteúdo da obra e seus dados em sua forma, correção e confiabilidade são de responsabilidade exclusiva dos autores, não representando a posição oficial da Editora Amplla. É permitido o download da obra e o compartilhamento desde que sejam atribuídos créditos aos autores. Todos os direitos para esta edição foram cedidos à Editora Amplla. ISBN: 978-65-88332-23-8 Editora Amplla Campina Grande – PB – Brasil [email protected] www.ampllaeditora.com.br 2021 Bergson Rodrigo Siqueira de Melo - Universidade Estadual do Ceará Carla Caroline Alves Carvalho - Universidade Federal de Campina Grande Cícero Batista do Nascimento Filho - Universidade Federal do Ceará Clécio Danilo Dias da Silva - Universidade Federal do Rio Grande do Norte Daniela de Freitas Lima - Universidade Federal de Campina Grande Denise Barguil Nepomuceno - Universidade Federal de Minas Gerais Dylan Ávila Alves - Instituto Federal Goiano Érica Rios de Carvalho - Universidade Católica do Salvador Gilberto de Melo Junior - Universidade Federal de Goiás Higor Costa de Brito - Universidade Federal de Campina Grande Italan Carneiro Bezerra - Instituto Federal da Paraíba Ivo Batista Conde - Universidade Estadual do Ceará João Henriques de Sousa Júnior - Universidade Federal de Santa Catarina Joilson Silva de Sousa - Instituto Federal do Rio Grande do Norte José Cândido Rodrigues Neto - Universidade Estadual da Paraíba Jose Henrique de Lacerda Furtado - Instituto Federal do Rio de Janeiro Josenita Luiz da Silva - Faculdade Frassinetti do Recife Luís Paulo Souza e Souza - Universidade Federal do Amazonas Luiza Catarina Sobreira de Souza - Faculdade de Ciências Humanas do Sertão Central Manoel Mariano Neto da Silva - Universidade Federal de Campina Grande Marcus Vinicius Peralva Santos - Universidade Federal da Bahia Marina Magalhães de Morais - Universidade Federal de Campina Grande Natan Galves Santana - Universidade Paranaense Nathalia Bezerra da Silva Ferreira - Universidade do Estado do Rio Grande do Norte Neide Kazue Sakugawa Shinohara - Universidade Federal Rural de Pernambuco Sabrynna Brito Oliveira - Universidade Federal de Minas Gerais Samuel Miranda Mattos - Universidade Estadual do Ceará Tatiana Paschoalette Rodrigues Bachur - Universidade Estadual do Ceará Telma Regina Stroparo - Universidade Estadual do Centro-Oeste Virginia Tomaz Machado - Faculdade Santa Maria de Cajazeiras Walmir Fernandes Pereira - Miami University of Science and Technology Wanessa Dunga de Assis - Universidade Federal de Campina Grande Wellington Alves Silva - Universidade Estadual de Roraima Yáscara Maia Araújo de Brito - Universidade Federal de Campina Grande Yuciara Barbosa Costa Ferreira - Universidade Federal de Campina Grande 2021 - Editora Amplla Copyright © Editora Amplla Editor Chefe: Leonardo Pereira Tavares Design da Capa: Editora Amplla Projeto Gráfico e Editoração: Higor Costa de Brito Dados Internacionais de Catalogação na Publicação (CIP) Sueli Costa CRB-8/5213 Santos, Yasmin da Silva Ciências da saúde [livro eletrônico] ensino, formação e pesquisa / Yasmin da Silva Santos...[et al.] – Campina Grande : Editora Amplla, 2021. 356 p. Vários autores: Fernanda Ferreira Evangelista; Fernanda de Oliveira Bottino; Arthur Daniel Rocha Alves; Tiago Savignon Cardoso Machado; Tainah Silva Galdino de Paula Formato: PDF ISBN: 978-65-88332-23-8 1. Saúde 2. Análise clínicas 3. Microbiologia 4.. Genéti 5. Imunologia 6. Farmacologia I. Evangelista, Fernanda Ferreira II. Bottino, Fernanda de Oliveira III. Alves, Arthur Daniel Rocha IV. Machado, Tiago Savignon Cardoso V. Paula, Tainah Silva Galdino de IV. Título CDD-613 Índices para catálogo sistemático: 1. Saúde : Pesquisa 613 Editora Amplla Campina Grande – PB – Brasil [email protected] www.ampllaeditora.com.br 2021 Esta obra é fruto da adaptação de alunos, professores e pesquisadores a uma era digital que nos abraçou com afinco, trazendo novas perspectivas na divulgação científica. Os trabalhos contidos neste e-book foram apresentados em formato de resumo no Congresso On-line de Ciências da Saúde de 26 a 29 de outubro de 2020 pelo grupo Ciência em Alvo. A possibilidade de realizar um evento totalmente on-line modificou a maneira de pensar e participar de eventos científicos. A pandemia do novo Coronavírus fez com que a necessidade de informação alcançasse o máximo de pessoas além de criar uma oportunidade para nos ensinar como a tecnologia favorece a todos os níveis acadêmicos. A troca de informações entre profissionais da saúde foi, e continuará sendo, fundamental para o enfrentamento dos desafios impostos no atual contexto. Desta forma, este e-book tem o objetivo principal de atualização e promoção de conhecimento a todos os profissionais da saúde, em especial, aos estudantes que estão iniciando na carreira científica. O conteúdo deste material é atualizado e diversificado com pesquisas quantitativas e qualitativas, atuando em diferentes áreas das ciências da saúde como: análises clínicas, microbiologia, biologia molecular/genética, imunologia, farmacologia, entre outros. Esta produção foi pensada como uma extensão do que foi realizado no evento científico para continuidade dos trabalhos que foram relevantes para a construção do mesmo e também, estimular a comunidade científica a dar seguimento aos trabalhos e divulgá-los mesmo que em períodos difíceis. Os organizadores desejam a todos uma ótima leitura e um bom proveito de todo o conteúdo disponível nesta composição. Yasmin da Silva Santos Biomédica, professora de análises clínicas. Fundadora do Grupo Ciência em Alvo Mestre em Ciências pelo Instituto Nacional de Infectologia Evandro Chagas (FIOCRUZ) Especialista em Análises Clínicas e Microbiologia pela Faculdade do Vale Elvira Dayrell - FAVED, Doutoranda de Fisiopatologia e Toxicologia (USP) Fernanda Ferreira Evangelista Enfermeira pela Universidade Estadual de Maringá (UEM) Colaboradora do Ambulatório de Toxoplasmose Gestacional no hospital Universitário de Maringá; Mestre em Ciências da saúde (UEM); Doutoranda em Ciências da saúde (UEM) Fernanda de Oliveira Bottino Médica Veterinária formada pela Universidade Federal Fluminense (UFF) Professora de Microbiologia dos Cursos Técnicos de Nivel Médio da Escola Politécnica de Saúde Joaquim Venâncio (EPSJV/ Fiocruz) Especialista em Patologia Clínica Veterinária pela Faculdade Qualittas Mestre em Ciências pelo Programa de Biologia Parasitária do Instituto Oswaldo Cruz (IOC/ Fiocruz) Arthur Daniel Rocha Alves Biólogo formado pela Universidade Estadual da Zona Oeste (UEZO) Mestre em Ciência pelo Programa de Biologia Parasitária do Instituto Oswaldo Cruz (IOC/Fiocruz) Doutorando em Medicina Tropical pelo Instituto Oswaldo Cruz (IOC/Fiocruz) Técnico em Gestão Hospitalar pela Escola Técnica Estadual Oscar Tenório (Faetec) Tiago Savignon Cardoso Machado Biólogo, Professor adjunto da Universidade do Estado do Rio de Janeiro (CAp / UERJ). Professor de Bioquímica dos cursos Técnicos de Nível Médio da Escola Politécnica de Saúde Joaquim Venâncio. Doutor em Ciência pelo programa de Pós Graduação em Fisiopatologia Clínica e Experimental (FISCLINEX) da UERJ Tainah Silva Galdino de Paula Bióloga formada pela Universidade Federal Fluminense (UFF) Professora de Biologia Molecular dos Cursos Técnicos de Nível Médio da Escola Politécnica de Saúde Joaquim Venâncio (EPSJV/Fiocruz) Mestre em Ciências pelo Programa de Ciências Médicas da Universidade do Estado do Rio de Janeiro (UERJ) Doutora em Ciências pelo programa de Biologia Parasitária do Instituto Oswaldo Cruz (IOC/Fiocruz) Pós-Doc pelo programa Brasil sem Miséria (CAPES/Fiocruz) CAPÍTULO I - aSPECTOS GERAIS DO SARS-COV-2: UMA REVISÃO DA LITERATURA ................................................ 9 capítulo ii - CRISPR/Cas como ferramenta biotecnológica aplicada à virologia................................ 20 capítulo iii - DETECÇÃO DOS VÍRUS EPSTEIN-BARR, CITOMEGALOVÍRUS E HERPESVÍRUS HUMANO 6 E 7 EM CRIANÇAS E ADOLESCENTES COM DOENÇAS EXANTEMÁTICAS ........................................................................ 35 capítulo iv - UTILIZAÇÃO DA SALIVA E DA URINA COMO ESPÉCIMES DE DIAGNÓSTICO DA DENGUE: ANÁLISE DA PRODUÇÃO LITERÁRIA ............................................................................................................................. 51 capítulo v - REVISÃO DA LITERATURA: LEISHMANIOSE TEGUMENTAR AMERICANA – MÉTODOS DIAGNÓSTICOS ... 67 capítulo vi - NÍVEIS DE CITOCINAS TNF-α, IFN-γ, E TGF-β E O PERFIL CLÍNICO-EPIDEMIOLÓGICO DE INDIVÍDUOS COM CORIORETINITE POR TOXOPLASMOSE, SUL DO BRASIL ........................................................................... 77 capítulo vii - NEUROCISTICERCOSE: ASPECTOS EPIDEMIOLÓGICOS, CLÍNICOS E LABORATORIAIS - UMA REVISÃO BIBLIOGRÁFICA ......................................................................................................................................
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