MEDICINE BuSummer 2019 • etVolume 104 • Numberin 1
The Case for Proton Therapy 1,000 Pancreas Transplants and Counting
Reshaping treatment for diabetes mellitus and end-stage renal disease
While pancreas transplant volumes across the nation are decreasing, the University of Maryland Medical Center numbers have steadily increased thanks to its multidisciplinary approach to treating diabetes mellitus and end-stage renal disease. Using a comprehensive evaluation and educational process helps identify patients who could benefit from simultaneous pancreas-kidney (SPK) more than standard kidney transplant alone.
• Patients wait a fraction of the time. Using SPK as a standard therapy for eligible patients with ESRD and DM can decrease wait times from an average of 6 years for a kidney alone to 90 days for an SPK.
• SPK can treat both Type I and Type II Diabetes. Formerly #1 in the nation thought of as a treatment for only Type I DM, SPK can benefit for simultaneous properly selected Type II patients and nearly all remain free of pancreas-kidney insulin after transplantation. transplants in The University of Maryland Transplant Center has also established a multidisciplinary approach to cardiac clearance for this challenging 2018* population. Using advanced non-invasive cardiac testing minimizes the need for cardiac catheterization and expedites cardiac clearance for surgery.
To refer a patient or consult with one of #1 in the region our physicians, call for solitary 410-328-2864. pancreas Learn more at umm.edu/pancreas transplants in Visit our Physician Briefs at physicians.umm.edu 2018*
* Based on volume data as of May 2019, Organ Procurement and Transplant Network, www.optn.transplant.hrsa.gov Bulletin Editorial Board Harry C. Knipp, ’76 Chairman Gary D. Plotnick, ’66 MEDICINE Vice Chairman John Allen, ’14 Frank M. Calia, MD, MACP Triesta Fowler-Lee, ’99 Nidhi Goel, ’10 Christopher Hardwick Sachin D. Kalyani, ’03 George C. Kochman III, ’08 Bu etin Brad D. Lerner, ’84 8 Cover story Jennifer Litchman Philip Mackowiak, ’70 Larry Pitrof Michael E. Reichel, ’74 The Case for Proton Therapy Ernesto Rivera, ’66 Walker L. Robinson, ’70 The Maryland Proton Treatment Center opened three years ago to a Julie Rosen great deal of fanfare and is arguably one of the most advanced centers of Jerome Ross, ’60 its kind. Yet it, as well as other centers across the nation, have struggled Semhar Z. Tewelde, ’09 Tuanh Tonnu, ’90 to maintain the necessary volumes of patients required to make them Joseph S. McLaughlin, ’56 thrive. Officials argue that the body of evidence in support of this therapy Chairman Emeritus is now growing as studies showing long-term health impacts from photon Medical Alumni Association Board of Directors treatment emerge. Stanford H. Malinow, ’68 President Brad D. Lerner, ’84 17 144th Medical Alumni Reunion President-Elect More than 500 alumni and Elizabeth L. Tso, ’79 Vice President guests participated in the 144th Paul A. Tarantino, ’87 Medical Alumni Association Treasurer Reunion in May. In addition to Harry A. Oken, ’83 Secretary milestone graduation anniversary John Allen, ’14 celebrations by classes ending Triesta Fowler-Lee, 99 in 4 and 9, the two-day event Nidhi Goel, ’10 Sachin D. Kalyani, ’03 included campus tours, an awards George C. Kochman, Jr., ‘08 luncheon and business meeting, Michael E. Reichel, ’74 Walker L. Robinson, ’70 the annual Historical Clinicopathological Conference, Semhar Z. Tewelde, ’09 and a medical school gala. Tuanh Tonnu, ’90 Directors Richard Keller, ’58 Honorary Regional Vice President 26 Alumna Profile: Karen Marcus, ’80 Gary D. Plotnick, ’66 Going Where Others Wouldn’t Neda Frayha, ’06 Helen Cheung, ’20 For many medical students the idea of specializing in pediatric Dr. E. Albert Reece, Dean oncology as a career is muted by fears of becoming perpetually Ex-Officio Larry Pitrof depressed. But Karen Marcus, ’80, wouldn’t have it any other Executive Director way. For the past 22 years, she has been division chief of pediatric University of Maryland School radiation oncology at Dana-Farber/Boston Children’s/Brigham and of Medicine Board of Visitors Women’s Cancer Center in Boston. Michael E. Cryor Chair Louis F. Angelos, Esq. Peter G. Angelos, Esq. Norman Augustine Departments Kenneth R. Banks Alfred R. Berkeley, III Marc P. Blum, PhD, LLB, CPA Dean’s Message Medicina Memoriae Student Activities Jocelyn Cheryl Bramble 2 30 36 Scott Burger Cynthia L. Egan 3 News & Innovations 33 Managing Money 37 Class Notes Robert E. Fischell, ScD Neda Frayha, ’06 Faculty News Advancement In Memoriam Carolyn B. Frenkil 15 34 38 Michael I. Greenebaum Jeffrey L. Hargrave 28 Historical Perspective 35 Recollections William E. Kirwan, PhD Harry C. Knipp, ’76 Stanford Malinow The University of Maryland Medicine Bulletin, America’s oldest medical For information on advertising, please contact: The Medical Valencia McClure Patricia J. Mitchell alumni magazine, is produced by the Medical Alumni Association of the Alumni Association of the University of Maryland, Inc. Edward Magruder Passano, Jr. University of Maryland, Inc., with support from the University of Maryland email: [email protected] Jacqueline Young Perrins School of Medicine and the University of Maryland Medical System. www.medicalalumni.org Abba David Poliakoff, Esq. The acceptance of advertising by this publication does not in any way Editor-in-Chief Timothy J. Regan constitute endorsement or approval by the Medical Alumni Association. Copyright © 1916 Medical Alumni Association Larry Pitrof Maurice Reid, ’99 Requests to reproduce articles should be directed to: Editor, Medicine of the University of Maryland, Inc. Melvin Sharoky, ’76 All rights reserved. Design Richard L. Taylor, ’75 Bulletin, 522 W. Lombard Street, Baltimore, Maryland 21201-1636, or by Brushwood Graphics email: [email protected]. Design Group Subscriptions are $20 per year (domestic) and $25 (overseas) Art Director Nancy Johnston
Summer 2019 • Volume 104 • Number 1 d ea messagen’s news INNOVATIONS Mower, ’59, Foxwell, ’80 Receive Dean’s Distinguished Gold Medal ach day our medical school community encourages and reminds me of its resilience in our resolution to improve the health and wellbeing of the citizens of Maryland and beyond. In Morton M. Mower, ’59, and the last several months our beloved institution has confronted some sobering realities. Most Milford M. “Mickey” Foxwell, recently, our health partner, the University of Maryland Medical System, has experienced Jr., ’80, received the dean’s very public scrutiny and a dramatic overhaul of its leadership. In these times of institutional distinguished gold medal during challenges it is vital that we remain focused on our missions to offer an excellent education to medical school convocation in our students, conduct exemplary scientific research, and provide exceptional patient care. We May. The award is presented to E individuals making high-impact cannot allow ourselves to become discouraged or distracted from our goals. Amid the issues surrounding us these days, we remember that we are a top-tier, research- contributions to medicine, intensive medical school conducting innovative work to unravel the most complex human science, or society in clinical diseases and conditions. We are also a premier healthcare provider in the state, region, and care, education, biomedical nation, which offers unparalleled patient care. An excellent example of this includes our research, or community service Maryland Proton Treatment Center (MPTC) profiled in this issue of theBulletin . In operation that have significantly improved for more than three years now, the MPTC is the only proton treatment center in the the health and wellbeing of Baltimore-Washington Region so far, and it is the first in the eastern United States to offer humankind. Mower, a cardi- ProBeam image guided intensity-modulated proton therapy—the most advanced and precise ologist, was co-inventor of the form of radiation therapy. automatic implantable cardio- In addition to providing our patients with another tool in the cancer-fighting toolbox, verter defibrillator. Foxwell Most recently, our the MPTC serves as a symbol of the school’s commitment to our patients. Prioritizing our recently retired from Maryland’s ability to offer this cutting-edge therapy demonstrates our care and concern—not just for the faculty as assistant professor of health partner, the patient’s illness, but for the patient’s life and quality thereof. With greater precision and the medicine and associate dean for admissions, a post he held for 29 University of Maryland capability to be administered in higher doses than alternatives, proton therapy minimally disrupts our patients’ schedules and regular routines. This provides a significant benefit to years. Medical System, has them, as they can move forward with their families, careers, and hobbies with a much higher Morton M. Mower, ’59 with Dean E. Albert Reece, MD, PhD, MBA degree of normalcy than what may be possible with other treatment options. Coupled with experienced very the integrative wellness program we began implementing at the MPTC just last year, our public scrutiny and comprehensive care and dedication to employing the most personalized approach makes me extremely proud. When our work considers more than just the disease, I know we are on track a dramatic overhaul for true innovation and sincere patient care. of its leadership. In May, our Medical Alumni Association celebrated its 144th Reunion, engaging alumni who have themselves overcome battles with cancer and other life-threatening diseases. The In these times reunion provided an excellent opportunity to reconnect, and it served as a reminder of the of institutional type of milestone for which our patients fight to have the opportunity to celebrate. This issue features an alumni profile onKaren Marcus, ’80, chief of the division of challenges it is radiation oncology at Boston Children’s Hospital. Dr. Marcus’ lifesaving work with our country’s youth makes it possible for her patients to celebrate their own milestones and attend vital that we remain their own reunions someday. focused on our The medical school has a rich, 212-year history of training the very best students, residents, and fellows who have significantly advanced the medical and biomedical research missions... enterprises of yesterday, today, and tomorrow. We had a great year of record-breaking accomplishments in FY 2019. I have no doubt that, with the right attitude, we can allow the challenges we face to form a current that would elevate us to even greater heights of achievement and aspiration this year. I am deeply and humbly honored to help lead and provide my unequivocal support for such an extraordinary and dedicated community.
E. Albert Reece, MD, PhD, MBA Milford M. “Mickey” Foxwell, Jr., ’80 with Sandra Quezada, ’06 and Joseph Martinez, ’98 University Executive Vice President for Medical Affairs and the John Z. and Akiko K. Bowers Distinguished Professor and Dean, University of Maryland School of Medicine
Medicine Bulletin Summer 2019 [2] [3] University of Maryland news INNOVATIONS
The Davidge family reunion, headed by Jacquelyn and William M. Davidge, IV, seated Garrett-Ray, ’00, in the front row Among Five Alumni Inducted into AOA Drs. Michael Fisher, lecturer Robert Vogel, and Gary Plotnick, ‘66 Stacy D. Garrett-Ray, ’00, vice presi- dent for the University of Maryland Medical System, was one of five alumni inducted into the Alpha Omega Alpha Vogel is Plotnick/Fisher Lecturer Medical Honor Society in spring. Resident Robert A. Vogel, MD, clinical professor of medicine at the Davidge Family Reunion in Baltimore inductees included Adam Zviman, ’17, University of Colorado Health Sciences Center, served as the and Manoj Racherla, ’16, both from second annual lecturer for the Gary D. Plotnick MD and Thirty-two descendants of John Beale Davidge, MD, gathered in Baltimore this spring to the department of internal medicine. In Michael L. Fisher MD Lectureship on May 10. The event is celebrate the accomplishments of the medical school’s founder and first dean. The effort was addition, Elizabeth Lamos, ’07, assistant named in honor of the two retired faculty members in the divi- organized by William M. Davidge, IV, John’s great, great, great grandson and his wife Jacquelyn. professor and assistant dean for student sion of cardiology. Vogel’s presentation was titled “The Future Attending were six third-greats, nine fourth-greats, and ten fifth-greats. Sixteen of them spent affairs, and Ana M. Sanchez, ’03 assistant of Cholesterol Treatment: The LDL Hypothesis in the era of the afternoon in Davidge Hall on April 19. professor of neurology and director of the PCSK9” and was held in the Shock Trauma Auditorium. department’s medical student education, were inducted as faculty nominees. Cyrus Hamidi, ’94, clinical instructor in the department of family and community Seventh Annual Malouf Lecture medicine, received the volunteer clinical faculty award. Warren E. Hill, MD, FACS, an expert in anterior segment surgery Thirteen senior-year nominees from the and the mathematics of intraocular lens (IOL) power calculations, class of 2019 and 13 junior-year nominees was the invited lecturer for the seventh annual Malouf Family were also admitted. The event was held at Lectureship in Contemporary Ophthalmology. Hill operates a the Baltimore Marriott Hotel on April 2. private practice in Mesa, Arizona, and is best known for helping physicians obtain the best possible accuracy for IOL power selec- tion. His websites attract more than 500,000 visits per year. The lectureship was established by the Malouf family and includes George Malouf, ’79, lecturer Warren E. Hill, MD, Alan Contributing writers to News/Innovations include: Bill Seiler • Karen Warmkessel • Julie Rosen Photos by: John Seebode • Mark Teske • Tom Jemski • Richard Lippenholz George, ’79, and Alan, ’85, who work at the Malouf Eye Center Malouf, ’85, and Marc Malouf, MD based in Camp Spring, Md.
Medicine Bulletin Summer 2019 [4] [5] University of Maryland ● INNOVATIONS news INNOVATIONS Mobile Addiction Treatment Unit Transplantation Aided Transplant physicians and researchers at Maryland joined aviation and engineering experts at the Unmanned Serving Eastern Maryland by Drone Aircraft Systems Test Site, part of the A. James Clark mobile addiction treatment unit School of Engineering at the University of Maryland, designed to provide state-of-the-art In a first-ever advance in human medicine and transplanta- College Park, to complete the landmark 2.8 mile, 9.52 care for opioid disorders is now tion, an unmanned aircraft has delivered a donor kidney minute flight on April 19. The research was also done serving Maryland’s eastern shore. to surgeons for successful transplantation in a patient with in collaboration with The Living Legacy Foundation of Health and addiction treat- kidney failure. Maryland, a non-profit organ procurement organization. ment officials from the Caroline The project leader was Joseph Scalea, ’07, assistant County Health Department, the professor of surgery, who was also one of the surgeons to Maryland Department of Health, the perform the transplant on a 44-year-old woman. She was Maryland Opioid Operational Command discharged one day after the procedure. Center, and the medical school Researchers hope this transport system may speed launched the Eastern Shore Mobile Care up organ delivery times, expand access to more organs, Collaborative in spring. It is believed to enhance safety, and ultimately improve patient outcomes. be the first of its kind in the country with capacity to provide access to treatments Eric Weintraub, ’86 (second from right), and the Mobile Addiction Unit team through videoconferencing. The telemedicine program is admin- consultation service and outpatient addiction treatment istered by Eric Weintraub, ’86, associate professor in service. They have been providing similar services in western the department of psychiatry and medical director of the Maryland for the past three years, prescribing buprenorphine school’s methadone clinic outpatient treatment services, and via their telemedicine program. The procedure utilizes an Christopher Welsh, ’93, associate professor of psychiatry encrypted and HIPAA compliant videoconferencing tech- and medical director of the medical center’s substance abuse nology linked to the medical school.
Transitions
Robert A. Chrencik, presi- continue his research and efforts to advance surgical tech- dent and chief executive niques including gamma knife radiosurgery and image-guided officer for the University of focused ultrasound. Graeme F. Woodworth, MD, professor of Patients as Art Maryland Medical System, neurosurgery is serving as interim chair. Price: $35 Paperback resigned in April. Chrencik Bankole Johnson, DSc, MD, had worked at the system for chairman of the department of Dr. Philip A. Mackowiak’s latest book, Patients as Art, more than 35 years and was psychiatry since 2014, has examines 40,000 years of medical history in drawings, elevated to the top resigned and is taking leave post in 2008. John from the institution to focus paintings, and sculptures. It features 160 full-color works of W. Ashworth is on his research and patented art, offering a pictorial review of medical history stretching serving as interim biotechnologies. He is recog- from the Paleolithic times to the present, and providing Robert A. Chrencik president and CEO. the author nized for his pioneering work insightful perspective on the combination of medical Philip A. Mackowiak, ’70 Howard Eisenberg, MD, chairman of the depart- in addiction medicine. Jill Bankole Johnson, DSc, MD history, science, and art. ment of neurosurgery for 23 years, has stepped down RachBeisel, MD, associate Emeritus Professor of Medicine professor of psychiatry, is serving as interim chair. The book is published by Oxford Press and is available for to return to the full-time faculty where he will Carolyn Frenkil & Selvin Howard Eisenberg, MD Passen History of Medicine purchase on the MAA website www.medicalalumni.org. Scholar University of Maryland School of Medicine
Medicine Bulletin Summer 2019 [6] [7] University of Maryland By Christianna McCausland
for Proton Therapy
Sharon Gallivan’s husband, Mark, was diagnosed with a malignant tumor of the esophagus in October 2018. Doctor’s told the couple that Mark, 76-years-old and in otherwise good health, had a high likelihood of recovery if he followed the typical treatment protocol of photon radiation with chemotherapy. But the couple was worried. “The tumor is close to his heart and lungs and the photon therapy could have affected them,” says Sharon from their home in Alabama. “We didn’t want to take that chance.” Through friends they learned about the Maryland Proton Treatment Center (MPTC). Proton therapy promised to deliver the maximum radiation dose with pinpoint precision and less impact to the surrounding healthy tissue. The couple boarded a plane for Maryland where they met with William F. Regine, MD, FACR, FACRO, the executive director at MPTC.
Regine explains that approximately 60 percent of cancer patients receive a course of radiation therapy as part of their treatment plan. For many, traditional photon is an acceptable option. However, 20-30 percent of patients are good candidates for proton therapy. Every patient at MPTC is evaluated to determine if proton is the right choice.
William F. Regine, MD, FACR, FACRO Photos by Richard Lippenholz ❺
MPTC First 1,659 Patients Treated (Through April 2019)
Head & Neck 13% Sarcoma Lymphoma GI 7% 4% 13% Other “Even though everyone there is 4% GYN 3% battling different cancers it is a very Thoracic happy place and everyone made Mark GU/Prostate 11% feel very comfortable,” says Sharon. 16% Breast The Gallivan’s story is compel- 11% CNS/Skull Base ling evidence that proton therapy is 18% a precise treatment that works with fewer side effects and medical compli- cations. Yet on the other side is a story of lagging patient volume. The Of these patients, 6% were pediatric cases and closure of some proton centers has 21% were re-irradiation cases grabbed national media attention. An April 2018 article in The New York “We are very appropriate stewards of this tech- Times reported: “Although most of the nology,” says Regine. “For many, the modern photon proton centers in the United States therapy is so insignificant there is no big gain if you are profitable, the industry is littered receive proton therapy. But on the flipside, for a with financial failure: Nearly a third of percentage of patients that photon therapy dose causes the existing centers lose money, have risk of significant injury to the heart, the gut, the lung, defaulted on debt or have had to over- the bladder, the rectum.” haul their finances.” Robert C. Miller, MD Proton therapy is highly recommended for pediatric patients, for example, whose young tissues are still growing. But others could benefit as well, including At a high level, what we want to do here is take part in Awareness and Collaboration in support of proton therapy is growing as studies re-irradiation patients who cannot receive more photon clinical research and federally funded clinical MPTC is arguably one of the most advanced centers of showing the long-term health impacts from photon treatment, or some patients with solid mass tumors near its kind. The 110,000-square foot building with its price treatment emerge. For example, there’s increased vital organs. Patients like Gallivan. trials to help generate knowledge tag of $200 million to build, has five treatment rooms evidence that women with left-side breast cancer may Upon arrival in Baltimore in January of this year, equipped with image-guided, Intensity Modulated be at risk for cardiac injury years after being treated with Mark Gallivan began a course of proton treatment—once for society. Proton Therapy, known as “pencil beam” technology. photon radiation. Additionally, numerous clinical trials a day for 28 days excluding weekends—with concurrent In autumn 2018, MPTC added deep thermal therapy to are taking place (including 19 that are currently open chemotherapy. Mark experienced illness related to the MPTC is currently the only such center in Maryland its treatment repertoire, a technology that enhances the and available to patients at MPTC) that will contribute chemotherapy toward the end of his treatment, but for and one of the few in the region. Nearly 85 percent affects of radiation for patients, especially those patients to the body of literature. the first four weeks he and Sharon were out experiencing of its patients are covered by insurance and thanks to who have had previous radiation therapy. “At a high level, what we want to do here is take part the Inner Harbor and enjoying restaurants. Maryland regulations, the treatment is delivered at the The staff is some of the best in the nation. In addi- in clinical research and federally funded clinical trials to “I’ve known people who had problems with radiation same price as conventional photon treatment. Yet it’s tion to Regine, who is a leader in the field of radiation help generate knowledge for society,” says Miller. and my husband had no problem at all,” says Sharon. ” The number of disease states identified as appro- treating only 700 patients a year despite its capacity oncology and a recognized expert in the areas of GI In May, Mark underwent surgery in his home state to treat 1,500. In 2018, under the leadership of a chief and CNS malignancies, MPTC’s new medical director, priate for proton therapy is also growing. Once affiliated to remove the remains of the tumor. His wife states he executive officer, Leigh T. Howe, MPTC moved to Robert C. Miller, MD, arrived this spring following mostly with prostate cancer, proton treatment has been is now home recovering. While they wish they never strengthen its financial position through the sale of tax- more than two decades at the Mayo Clinic. There he found to have clinical benefits in lung, oropharynx, needed to be at MPTC, Sharon says the experience free municipal bonds, raising $277.4 million. served as vice chair of radiation oncology for proton hepatocellular and nasopharynx cancers, chordomas, was wonderful. MPTC’s concierge organized their daily Why is a treatment so full of promise struggling for a research. He’s served as the study chairman for five sarcomas and others. Given this landscape, Miller states travel to the center from their hotel, and in addition to foothold? national randomized clinical trials. the national capacity for proton treatment is actually treatment the couple used the on-site wellness center. Miller states that while protons have been around for below the ideal. decades, this is a pivotal moment. The body of evidence
Medicine Bulletin Summer 2019 [10] [11] University of Maryland ❺
“We have the capacity to treat Doubling Down roughly 15,000 patients a year in In June 2018, MPTC hired a new chief executive officer,L eigh Howe, an executive this country,” Miller posits, “and with a background in commercial banking and private equity with a healthcare focus. we know many, many more could Her directive was clear. benefit.” “There was a major push to delever the balance sheet by issuing tax-exempt bonds Looking at a 200 miles radius through a conduit, the Wisconsin Public Finance Authority, lowering our interest of MPTC and accounting for expense, in essence, by half,” she explains. “We would pay off our senior lender and annual cancer cases in the general replace that debt with bonds.” population, the 20 percent that When the bond sale took place in August it exceeded expectations, something would qualify for proton treatment Howe attributes to MPTC’s track record of successfully treating patients. The bond translates into over 28,000 cases. sale provided an 18-month financial reserve and Howe intends to use that time and To start to tap into that group of money wisely to get MPTC to a point where “it can fly on its own.” Howe’s goal is to patients, Miller says there will be treating 1,000 patients a year, a milestone she wants to reach within five years. be a focus in the next two to five “We’re all about volume. Volume is what will get the bonds repaid,” she states. years on increasing proton use “We need to find the barriers to referrals and break them down.” with re-irradiation patients, those MPTC’s plan to break those barriers includes expanding the affiliate program, with complex malignancies in the enhancing the existing connection with the Greenebaum Cancer Center, and head and neck base, in the chest (like lung or esophagus cancer) and women with left-side breast cancer. Clearly the patients are out there, and in Maryland, a price neutral state, cost does not appear CEO Leigh T. Howe Potential Number of Patients Benefitting to be a barrier to proton treatment. Awareness and a lack of collabora- from Therapy at MPTC a more delicate matter. Many doctors are affiliated with tion across hospital systems may be to blame. a specific hospital and those hospitals have their own “I think this is a matter of awareness and Total Population photon treatment centers, expensive centers that are 48,287,677 education— we need to be, and we are, out there giving important revenue drivers for the hospitals themselves. < 200 Miles from Center It is possible that doctors encounter pushback Treatment Rooms 5 from administrators if they refer patients to x Hours per day 16 Cancer Cases The Gallivan’s story is compelling evidence that proton therapy another center for care. 234,678 To combat this, MPTC has a strong and x Days per year 300 486/100,000 Population is a precise treatment that works with fewer side expanding affiliate program. To increase acces- = Minutes beam time per year 1,257,120 effects and medical complications. Yet on the other side is sibility to the treatment, physicians can be Radiation Cases credentialed at MPTC, become adjunct faculty, 140,806 / Minutes per treatment fraction 28 @60% of Total Cases a story of lagging patient volume. and then bring their patients to MPTC for proton treatment. The program has success- / 29 Fractions per patient = estimated fully brought in doctors from Inova Fairfax patients treated per year 1,548 Proton Cases Hospital in Virginia, the York Cancer Center in 28,161 talks all over the state and the region,” says Regine. @ 20% of Radiation Cases Pennsylvania and physicians from the Annapolis region. Educating physicians who are set in old treatment
protocols is one thing; the challenge of collaboration is Estimated Patients Treated per Year 1,548
Medicine Bulletin Summer 2019 [12] [13] University of Maryland ❺
Faculty
continuing to support clinical trials. Howe plans adver- “and there’s some basic science evidence that we may be news ❖ Daniel Morgan, tising to encourage self-referrals and notes that while able to protect normal tissues better than we can with and immunology, and director, Institute for Genome Sciences; Jacques Ravel, PhD, MD, associate pro- some of those patients may not qualify for proton treat- a conventional dose.” He adds that FLASH could also professor, department of microbiology and fessor, department ment, a resident evaluates every call. The more people eliminate complications with tumors that move, like immunology; Owen White, PhD, profes- of epidemiology & talking about proton, the better. those in the liver. Publications sor, and Lynn Schriml, PhD, associate public health, was While centers nationally have struggled and closed, “Maryland is a great place to look at these questions professor, both from the department of recipient of the ❖ Maureen Black, Howe says MPTC has many differentiators that make because we have the right equipment to do this that not epidemiology & public health; and all from Mary Betty Stevens PhD, the John A. the Institute for Genome Sciences, co- Award of the it uniquely strong, not least of all its affiliation with a every national proton center has,” he concludes. “And Scholl, MD and American College authored “Towards Unrestricted Usage of Daniel Morgan, MD prestigious academic center. And while referrals may we have a team of very motivated and excited people Mary Louise Scholl, Public Genomic Data,” published in Science of Physicians for be lagging, other institutions clearly see the poten- with great training.” MD Professor on January 25. his contributions in clinical research. The in Pediatrics, award was presented in February. tial in proton treatment, too. Far from shying away ❖ Maggie Matern, BSc, PhD candidate; Preserving Quality of Life co-authored a from this technology, high-profile neighbors including Yoko Ogawa, PhD, postdoctoral fellow; ❖ David Rasko, Treating cancer is about survival, but it is important commentary in The Georgetown and Johns Hopkins are doubling down and Béatrice Milon, PhD, research supervisor; PhD, profes- to preserve quality of life as well. Radiation can be as Lancet, “Optimising Maureen Black, PhD Mark McMurray, MS, research technician; sor, department building their own proton centers in Washington, D.C. the Continuum destructive as it is effective; patients can require feeding and Ronna Hertzano, MD, PhD, associ- of microbiology Howe welcomes the newcomers. of Child and tubes and other invasive ate professor; all from the department and immunology, “We’re not competing Adolescent Health and Development,” procedures. Depending on of otorhinolaryngology head and neck Institute for Genome against them because the published March 13. a tumor’s location there are surgery; and Yang Song, PhD, bioinfor- Sciences, and more centers that are out therapy is highly recommended ❖ Timm Dickfeld, Richard Zhao, Proton risks to cognitive functioning matician, Institute for Genome Sciences, there, within reason, the MD, PhD, profes- were among the co-authors of “Helios is a PhD, professor, or the potential to lose David Rasko, PhD more awareness spreads,” for pediatric patients... sor, department Key Transcriptional Regulator of Outer Hair department of the use of one’s taste buds. of medicine, pathology, were elected as fellows of the she says. Cell Maturation,” published in Nature on whose young tissues are still growing. Because proton therapy co-authored “ACC/ November 21, 2018. American Academy of Microbiology. Investing in the decreases tissue risk, it can AATS/AHA/ASE/ ASNC/HRS/SCAI/ Future also decrease complications * SCCT/SCMR/STS Grants & Contracts Another innovation Honors & Awards related to surgery, wound 2019 Appropriate Timm Dickfeld, MD, PhD ❖ ❖ Joana Carneiro MPTC champions is a healing, and the risk of Use Criteria for Iris Lindberg, da Silva, PhD, move to introduce greater permanent damage that Multimodality PhD, professor, associate profes- efficiency in the treat- Imaging in the Assessment of Cardiac department of impacts quality of life. sor, department Structure and Function in Nonvalvular anatomy and neuro- ment itself. If the course “I had at least three head of microbiology Heart Disease: A Report of the American biology, was elected of treatment could be and neck patients in the first and immunology, College of Cardiology Appropriate Use as an American reduced from six weeks, Institute of Genome year that maybe three to six Criteria Task Force, American Association Association for Sciences, for example, or the months after treatment said, for Thoracic Surgery, American Heart the Advancement received a four- length of each session “My taste is back to normal,” Association, American Society of of Science (AAAS) Iris Lindberg, PhD Joana Carneiro da Silva, year, $3,577,550 could be shortened, that Echocardiography, American Society of Fellow in recogni- PhD Regine recalls. “That’s R01 award from Nuclear Cardiology, Heart Rhythm Society, tion of her achievements in advancing would greatly impact the because all the taste buds National Institute of Allergy and Infection Society for Cardiovascular Angiography and science. The induction ceremony was capacity for patient flow. have been spared. That’s Diseases for “Genome-Wide Sieve Analysis Interventions, Society of Cardiovascular held at the 2019 AAAS Annual Meeting in Thus FLASH ultrahigh and Immunological Validation to Identify amazing to see. It’s one thing Computed Tomography, Society for Washington, D.C., in February. Targets of Protective Efficacy in Field Trials dose-rate radiation is to cure a patient, but cure at Cardiovascular Magnetic Resonance, and ❖ Maureen of a Whole-Organism Malaria Vaccine.” something MPTC is what price?” the Society of Thoracic Surgeons,” pub- McCunn, MD, researching in a laboratory “With proton we have lished in the Journal of the American College MIPP, FCCM, ❖ Joseph Cheer, PhD, profes- setting. the capacity to cure while of Cardiology on FASA, professor, sor, department “FLASH holds the February 5. department of anes- dramatically increasing the of anatomy and Others could benefit as well, including ❖ Claire Fraser, thesiology, program potential to give radiation quality of life for patients.” neurobiology, was PhD, the Dean’s in trauma, was therapy with protons or re-irradiation patients who cannot receive more That is a powerful awarded a five-year, Endowed Professor named the chair of $1,738,125 grant other beams in a frac- message and one MPTC in the School of American Society of photon treatment, or some patients with solid Maureen McCunn, MD, Anesthesiologists from the National tion of a second, not plans to evangelize to reach Medicine, professor, MIPP, FCCM, FASA Committee on Institute on Drug minutes,” says Miller, mass tumors near vital organs. patients in need. department of med- Joseph Cheer, PhD Abuse NIDA/NIH icine, microbiology Trauma and Emergency Preparedness. Claire Fraser, PhD
Medicine Bulletin Summer 2019 [14] [15] University of Maryland 144th Medical Alumni Association
Faculty news Reunion 2019 grant from the ❖ Mary Kay Lobo, National Institutes PhD, associate for “Cannabinoid Receptor Control of of Health for “Hip professor, depart- a DRN to VTA Pathway and its Role in Muscle Power, ment of anatomy Affective States.” Also, within Cheer’s lab, Lateral Balance and neurobiology, Dan Covey, PhD, assistant professor, was Function, and Falls in received a five-year, awarded a $1,051,544 K99/R00 award from Aging.” $2,171,420 grant the NIDA/NIH for “Neural Circuit Control of President’s Message ❖ Achsah Keegan, from the National Mesolimbic Dopamine and Reward.” Institute of Drug Sanford H. Malinow, ’68 Vicki Gray, MPT, PhD PhD; profes- Mary Kay Lobo, PhD ❖ Gary Fiskum, sor, department Abuse for “Ventral The 145th Drs. Ronald and Richard Taylor MAA President PhD, Matjasko of microbiology Pallidum Molecular Mediators in Cocaine Professorship and immunology, Addiction.” ore than 500 alumni and guests enjoyed two days for Research in center for vascular ❖ Thomas MacVittie, PhD, professor, 2019–2020 of Reunion activities in spring. In addition to rekin- Anesthesiology and and inflammatory department of radiation oncology, was Medical Alumni Board vice chair, profes- dling old friendships, participants had an opportunity diseases; Rose awarded a $2,599,626 subcontract from Stanford H. Malinow, ’68 sor, department to witness firsthand the enormous growth of our medical Viscardi, MD, SRI International for “Assess the Efficacy of President of anesthesiology; professor, depart- Filgrastim (Neupogen®) or Peg-Filgrastim campus. There were tours of the medical center, medical Brad D. Lerner, ’84 Claire Fraser, ment of pediatrics; (Neulasta®) on Mitigating Co-Morbidities school, and around the extended campus. A presentation by the Gary Fiskum, PhD President-Elect M dean provided details on all three components of our operation—education, PhD, the Dean’s Achsah Keegan, PhD and Stefanie Vogel, and Mortality of Multi-Organ Injury (MOI) Endowed Professor in the School of PhD, professor, Associated with Concurrent GI-ARS, Elizabeth Tso, ’79 research, and clinical practice. During our awards luncheon graduates partic- Medicine, professor of medicine, micro- department of microbiology and immunol- Prolonged GI Injury and Delayed Effects Vice President ipated in the annual business meeting of the Medical Alumni Association at biology and immunology, and director, ogy, received a five-year, $3,053,150 grant to Lung and Kidney Characteristic of the Paul A. Tarantino, ’87 historic Westminster Hall where we honored several colleagues as well as the Institute for Genome Sciences; Rosemary from the National Institute of Allergy and DEARE in NHP Exposed to 10 Gy Using the Treasurer golden anniversary class of 1969. The annual Historical Clinicopathological Kozar, MD, PhD, professor, department Conference, an update on Davidge Hall, and a lecture titled “Patients as Infectious Diseases for “IL-4-Activated PBI/BM 2.5 Protocol.” Harry A. Oken, ’83 of surgery; and Nicole Klinedinst, PhD, Art” balanced the celebration with intellectual enrichment. The Reunion Macrophages: Contribution to Allergic Lung ❖ Fabio Romerio, Secretary MPH, MSN, RN, FAHA, associate profes- Inflammation Linked to Viral Infection.” PhD, assistant concluded with a Saturday evening gala featuring great music and dancing sor from the University of Maryland School John Allen, ’14 ❖ Myron Levine, professor of medi- that attracted more than 1,000 people. If you haven’t been to a Reunion of Nursing, were awarded a three-year, Triesta Fowler-Lee, ’99 MD, DTPH, cine, Institute of recently you really need to make the effort when your next milestone gradu- $3.5 million grant from the U.S. Army and Nidhi Goel, ’10 The Simon and Human Virology, ation anniversary comes around. Air Force for “Genomics, Microbiomics, Sachin D. Kalyani, ’03 Bessy Grollman received a five- If it’s activity you seek, don’t wait for your Reunion to act. The Medical and Bioenergetics-Based Personalized George C. Kochman, Jr., ’08 Distinguished year, $4,005,581 Alumni Association has a very active board and welcomes your involvement. Treatment for Head Trauma Patients at Risk Michael E. Reichel, ’74 Professor of R01 grant from The Davidge Hall Committee and Bulletin Editorial Board are two of our for Sepsis.” The research will be conducted Walker L. Robinson, ’70 Medicine, associ- the National seven standing committees that expect to be busy this year. We’re moving within the Center for Shock, Trauma, and Semhar Z. Tewelde, ’09 ate dean for global Fabio Romerio, PhD Institute of Allergy into the next phase of restoration for our historical building, as planning is Anesthesiology Research. Tuanh Tonnu, ’90 health, vaccinol- and Infectious Directors now underway to restore the dome and gable. We’re also looking at internal ❖ Claire Fraser, PhD, the Dean’s Myron Levine, MD, ogy, and infectious Diseases for “Sustained HIV Remission Via work once the structure is watertight. Regarding the quarterly alumni maga- DTPH Endowed Professor in the School of diseases, center for Sequence-Specific Epigenetic Silencing of zine, we are exploring electronic delivery as an option to those who prefer it. Medicine, professor of medicine, micro- vaccine development and global health, Latent Proviruses.” We’re always looking for suggestions on alumni to profile and feature stories biology and immunology, and director, was awarded $2,500,000 from the National ❖ Dennis Sparta, PhD, assistant to write that will be appreciated by our readership. Institute for Genome Sciences; David Institute of Allergy and Infectious Diseases professor, department of anatomy and neu- I ask for your continued support this year and invite you to become more Rasko, PhD, professor, department of for “Active Vaccination and Passive Antibody robiology, received a five-year, $1,125,000 actively involved in our great volunteer organization. microbiology and immunology; and Owen Strategies to Prevent Disease Caused by grant from the National Institute on Upon graduation, Stan Malinow, ’68, interned at Baltimore’s Sinai Hospital where he remained for his White, PhD, professor, department of Multidrug-Resistant Bacterial Pathogens.” Alcohol Abuse and Alcoholism for “CRF first year of residency training in internal medicine. He traveled to Indiana University Hospital in 1970 for epidemiology & public health, associate ❖ Iris Lindberg, PhD, professor, depart- Neural Circuits of Binge Drinking.” additional residency training, spent two years in the U.S. Army, and then returned to Sinai in 1973 to serve director, also from the Institute for Genome ment of anatomy and neurobiology along as chief resident. Malinow has been in private practice his entire working career, and since 2004 has been a Sciences, received a five-year, $17,552,940 ❖ Li Zhang, PhD, associate profes- with co-principal investigator Nigel Maid- partner with Drs. Malinow, Oster and Malinow, PA, a concierge practice that he shares with son Louis, ’94. grant from the National Institute of Allergy sor, department of physiology, center ment, PhD, from the University of California, He and wife Rosalyn have another child and five grandchildren. and Infectious Diseases for “A Genomics for vascular and inflammatory diseases, Los Angeles, was awarded a five-year, Based Investigation of the Determinants received a four-year, $1,868,061 grant $2,600,000 grant from the National Institute of Polymicrobial Infectious Disease from the National Heart, Lung, and Blood on Aging for “ProSAASMediated Neuro- Outcomes.” Institute for “Targeting the Proinflammatory protective Mechanisms in Alzheimer’s and Activity of Integrin Mac-1 for Treatment of ❖ Vicki Gray, MPT, PhD, assistant profes- Parkinson’s Diseases: The Role of Secretory Atherosclerosis.” sor, department of physical therapy and Chaperones in Neurodegeneration.” rehabilitation science, received a $2,833,578 *Grants & Contracts of $1 million and above
[17] University of Maryland Medicine Bulletin Summer 2019 [16] Reunion 2019
Awards Luncheon & Business Meeting
More than 120 alumni and guests were in attendance for the Harry and Vivian Kramer Awards Luncheon & Annual Business Meeting on May 3. The event, held in Westminster Hall, honored the golden anniversary class of 1969 and also recognized several alumni. June K. Robinson, ’74, received the MAA Honor Award and Gold Key, presented since 1948 for outstanding contributions to medicine and distinguished service to mankind. Donna L. Parker, ’86, was recipient of the MAA Distinguished Service Award, presented since 1986 for outstanding service to the MAA and medical school. In addition, Melissa A. McDiarmid, ’79, and Maurice N. Reid, ’99, received alumni leadership awards for exemplary leadership in the medical profession. Two senior students—Paige Kennedy and Ese Ikheloa—were cited for their participation on the MAA Student Advisory Council, and during the annual election of officers and ❻ directors Stanford H. Malinow, ’68, was elected president.
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❶ Alumni Leadership Award recipient Melissa A. McDiarmid ’79 ❷ Alumni Leadership Award recipient Maurice N. Reid, ’99 ❸ Herta Baitch and husband Arthur, ’54, celebrating his 65th graduation anniversary at the luncheon ❹ Visiting at the awards luncheon were Clayton Raab, ’74, Emerson Walden, ’74, and Susan Panny, ’74 ❺ Gold Key winner June K. Robinson, ’74, with Distinguished Service recipient Donna L. Parker, ’86 ❻ Robin Williams, ’89, Robert Maupin, ’89, and Daniel Croteau, ’89, at the awards luncheon. ❼ MAA president Neda Frahya, ’06, thanks outgoing board members Mark Schneyer, ’06, and Karen Meckler, ’83 for their service as directors on the board. ❽ Senior Ese Ikheloa and Paige Kennedy were recognized for their service on the MAA Student ❽ ❾ Advisory Council ❾ Celebrating their 50th at the awards luncheon were Howard Davidov, ’69, and Barry Friedman, ’69 ❺
Medicine Bulletin Summer 2019 [18] [19] University of Maryland ww Reunion 2019 St. Francis of Assisi Died of Leprosy, According to Man and Machine Medical School Gala
patho In a battle pitting man versus machine, physicians around the world and a supercomputer ico lo in g l ic rendered their diagnoses on what caused the death of a saint who lived 800 years ago during this C a l l year’s Historical Clinicopathological Conference (HCPC). a C
c o i For the first time in 26 conferences, this year’s event used the popular crowd-sourcing tech- n
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t nique to poll more than 500 physicians in 46 countries on how St. Francis of Assisi died and
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compared their top answer to the intelligence of a supercomputer.
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T St. Francis (circa 1181–1226) developed fevers, chills, severe abdominal
pain, delirium, blindness, open sores, and other symptoms over a period of more than 20 years while living in Europe and traveling to north Africa. What could have caused such suffering? Eliot Siegel, ’82, professor and vice-chair of diagnostic radiology and nuclear medicine at Maryland and an early supporter of the use of super computing in medicine, and medical crowd-sourcing expert Reza Manesh, MD, a hospitalist and assistant program director for clinical reasoning for the Osler Medical Training Program at Johns Hopkins University School of Medicine, presented their diagnoses during the May 3 confer- ence in Davidge Hall. Siegel fed information into the Isabel DDx, a super computer used by physicians around the world to help improve their accuracy when diagnosing diseases. Isabel received only the information Dr. Siegel submitted into the system as if the ❶ ❷ ❷ patient were alive today. The specifics included, age, 40 to 49 years old.T ravel history, Egypt. Illnesses, paresthesia, which can manifest as a numbness of the skin including the hands, feet and face; skin lesions, eye discharge, photosen- sitivity. Within seconds he received his answer: leprosy, most likely borderline tuberculoid. “What surprised me was Isabel came up with the diagnosis from those symp- toms without knowing the historical background, especially without knowing that the historical figure had a ‘special affinity for lepers’ and actually washed the skin and the wounds of lepers,” Siegel said. Manesh entered St. Francis’ information into the Human Diagnosis Project, an open collective intelligence system, to seek answers. Its contributors are more than 20,000 medical professionals—primarily doctors, residents and students across a broad spectrum of specialties. Each contributor provides insight independently and can’t see suggestions from other users. “By combining insights from multiple physicians with diverse perspectives… into a collectively weighted list, you’re more likely to arrive at the right decision,” His crowd-sourcing supplied the same answer: leprosy. Sister Joanne Schatzlein, a member of the Sisters of Saint Francis of Assisi, who also presented at the HCPC, spent ❸ ❹ nearly eight years in the 1980s—three working with Daniel P. Sulmasy, MD—researching whether St. Francis had leprosy. When she raised the question, it was the first time the leprosy theory was presented, she said. She and Sulmasy published their ❶ David, ’74 and Marcie Zisow ❺ findings in St. Bonaventure University’s Franciscan Studies. ❷ Jonathan Fischell, ’19, Stefanie Zaner, ’19, Paige The book was republished in 2014 under the title Francis the Kennedy, ’19, and Danielle Winston at the Gala Leper, Faith, Medicine, Theology, and Science. ❸ Wilson Lamy with wife Sandra Quezada, ’06, “I’m just so impressed our research has been supported Christopher Parrino, ‘21, Catherine Panasenkov, and in a pretty high-tech level,” Schatzlein said. "I Jack Siglin, ’21, at the Gala just laughed out loud, thinking how long we This year’s CPC presenters included Reza Manesh, MD, Joanne ❹ Robert Helsel, ’69, visits with classmate Tracy researched and pondered, and the computer Schatzlein, OSF, and Eliot Siegel, ‘82 Spencer, ‘69 just spit it out. Dan and I will have to ❺ Enjoying the Medical School Gala were Akina celebrate again!" Tamaki, Eleanor Tanno, Paige Luneburg, Brandon Smith, Berje Shammassian, and Joseph Mechak from the class of 2014
Medicine Bulletin Summer 2019 [20] Saint Francis in Meditation, oil painting by Francisco de Zurbarán (1639) University of Maryland ❺ Reunion 2019
Class Parties
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❶ Class of 1954 at the Annual Awards Luncheon ❷ Class of 1959 at the Maryland Club ❸ Class of 1964 at the Center Club ❹ Class of 1974 at the Center Club ❺ Class of 1969 at the Center Club ❻ Class of 1979 at the Maryland Club ❷
[Your favorite reunion photos can be downloaded at www.medicalalumni.org]
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Medicine Bulletin Summer 2019 [22] [23] University of Maryland ❺ Reunion 2019 Calls for 2020 Awards Nominations! Alumni, faculty, and friends are invited to send in their nominations for two MAA-sponsored awards by November 1, 2019. The Honor Award & Gold Key is presented to a living graduate for outstanding contributions to medicine and distinguished service to mankind. Factors considered in the selection process include impact of accomplish- ments, local, national, and international recognition, supporting letters, and publications. The Distinguished Service Award is presented for outstanding service to the Medical Alumni Association and University of Maryland School of Class Parties ❶ ❹ Medicine. The awards are to be presented during the annual Reunion Recognition Luncheon on Friday, May 1, 2020. Letters of nomination for both awards must include a curriculum vitae and should be addressed to: George C. Kochman, Jr., ’08, Chair, MAA Awards Committee, 522 W. Lombard St., Baltimore, MD 21201-1636 or emailed to: [email protected]
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❶ Class of 1984 at the Maryland Club ❷ Class of 1989 at the Maryland Club [Your favorite reunion photos can be ❸ Class of 1994 at the Center Club downloaded at ❹ Class of 1999 at the Center Club www.medicalalumni.org] ❺ Class of 2009 at Cedar Lane Park ❻ Class of 2014 at Barcocina
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Medicine Bulletin Summer 2019 [24] [25] University of Maryland By Sandra McKee alumna profile Karen Marcus, ’80
During her sophomore year, while talking to a graduating senior, she asked what field he was going into. He said pediatric oncology and the revelation came. It was the answer: helping children through her work as an oncologist was what she wanted to do. But that’s when others began Going Where Others Wouldn’t telling her it would be too depressing. However, a pediatric residency at the Children’s Hospital of Philadelphia and a pediatric oncology fellowship at the National Cancer Institute inspired her. ould there be a more depressing calling than being a pediatric radiation oncologist? Watching A second source of inspiration was a conversation with world-renowned the youngest, most vulnerable patients battle life’s deadliest disease from a front-row seat? Maryland professor Robert Gallo, MD. The co-discoverer of HIV as the Yet Karen Marcus ’80, after three decades in the field, wouldn’t have it any other way. cause of AIDS, he told her it is “significant to carve out a unique niche.” “In the late 1970s, when I chose to become a pediatric oncologist, people said I’d change my Very few radiation oncologists who treat children have training in all three mind because it was too depressing,” says Marcus, division chief of pediatric radiation oncology disciplines of pediatrics, pediatric oncology, and radiation oncology. “I at Dana-Farber/Boston Children’s/Brigham and Women’s Cancer Center in Boston. “And it can thought, why not consider pediatric radiation oncology?” be distressing, but tremendous progress has been made and it is a wonderful field for me.” It would require another career decision, “yet another training program, It is a subspecialty not many radiation oncologists want to pursue. “Not many want to treat children this one in radiation oncology.” In 1986, she made the leap to Harvard with cancer,” she says. “Although we all recognize the potential long term side effects in children, radio- and its joint center for radiation therapy, and then at Dana-Farber/Boston therapy can be critical to the cure of many children and can provide palliation for those we cannot cure. Children’s/Brigham and Women’s Cancer Center in Boston. Very few radiation “It’s been wonderful to watch our department grow and technology advance” she continues. “We’ve For the last 22 years she has been the division chief of pediatric radia- oncologists who become a really outstanding department. I remember visiting the Dana-Farber as a medical student and tion oncology there. thinking, ‘Wow!’ I never imagined at that time, that one day I would be here. For me to be the division “That trio of specialties has proved to be ideal for me,” says Marcus, 66. “I don’t administer treat children chief…it’s an important position and I’m honored to be here.” chemotherapy, but rather radiotherapy which is part of the many treatment protocols in pediatric have training in all She pauses, thinking back on how she got here. oncology. In addition, radiotherapy can be a great modality for palliative treatment. Radiation is “I did my residency in radiation oncology at Harvard, was offered a job and here I stayed for what has very effective in easing pain. three disciplines truly been my ‘dream job,’ ” she says. “It’s been a great career path,” the doctor says. “Many residents ask, ‘Radiation vs oncology?’ It of pediatrics, In addition to the job satisfaction she finds treating her patients with compassion and love, there is would be very hard for me to choose. Had I not have decided to take this route, I would never have pediatric oncology, another reason she finds joy in what she does. It led her to the most important people in her life—her met my husband. From England, he just happened to be here, in Boston, visiting a cousin.” husband, Michael, and their daughter, Shoshana, now 21. Had she not been working in Boston, chances His work as an independent investment manager dovetailed with being a stay-at-home dad, too, and radiation are she and Michael never would have met. when they adopted their daughter as a seven-month-old from China. That was a gift to Marcus, as oncology. “I Karen Marcus’ story begins in Baltimore, where she was born. Long before she attended Milford Mill well, as she pursued her own talent, a singular focus on her work. It is that focus that worries her High School, she decided she wanted to become a doctor. That came when she was seven, recovering husband. thought, why from an operation to fix a kidney abnormality. “I really don’t talk about things at home,” Marcus says. “It’s too upsetting to talk about children not consider “While I was in the hospital, I just decided medicine appealed to me,” Marcus says. “That’s when I got with cancer. And I’m never really away from it. Not on weekends, not on vacations. It’s a chal- pediatric radiation the bug. I came from a family of teachers and for a while I thought I’d be a teacher, but I kept coming back lenge for him to be married to a physician. My job isn’t emotionally a good thing.” to medicine.” Marcus admits she hasn’t left much time in her life for fun or other interests outside of those oncology? But what kind of medicine? two most important individuals in her life—husband and child. Before medical school, she graduated from Stern College of Yeshiva University in New York City, “I used to enjoy ballet classes for decades,” she says, remembering. “Now I come home after an where she majored in biology and Jewish Studies. intense day at the hospital, I am not eager to go out. But we do enjoy classical music concerts and “I was interested in my religion and I had three wonderful years at Yeshiva, but I didn’t want to remain watching foreign movies on TV. Foreign movies, especially the ones from Scandinavia, are very in New York City,” she says. “At the same time I started wondering whether I wanted to become a physi- absorbing, a good way to take my mind off my work.” ” cian or a laboratory researcher.” These days there are thoughts that one day she will be retiring. When, she doesn’t exactly Eventually, as she made her way through medical school in Baltimore, she would think during each know— but she sees a glimmer. rotation, after pathology, pediatrics, and neurology, ‘maybe this is what I want to pursue.’ Eventually, she “I love my job,” she says. “But I love my husband more and I am looking forward to spending realized she needed the interaction that developed with patients, not the sterile environment that went more time with him.” with lab research.
Medicine Bulletin Summer 2019 [26] [27] University of Maryland historical perspective By Mary Ellen Leuver and Henry Bergles
At his experiment’s outset, Milgram sought to create conditions that might demonstrate how and if Americans might display the obedience to authority that many citizens had claimed was their The Nature of Evil: motivation to commit atrocities in Nazi Germany. Studying the Human Condition in the Late 20th-Century At random, the students were separated into propor- telling. Although most histories focus on the aspects of Nazi tional groups of guards and prisoners. At the outset of the compliance motivating Milgram’s studies, the context of the experiment, the “prisoners” were taken from their homes, Cold War and the fear of what your neighbors were capable of “‘It was horrifying,’ the professor moaned. ‘I got so depressed introduced to a person who they believed was a fellow partic- blindfolded, removed to the “prison” in the Stanford base- permeates the Milgram study and its subsequent publicity. seeing people deteriorate. They were falling apart before my ipant—a person who was in fact a paid actor—and misled ment, searched, stripped, changed into jumpsuits, and given As the 1960s progressed, the Great Society under Lyndon very eyes. The inmates were crying to be let out—and the to believe that he or she was randomly assigned the role of identification numbers. Johnson sought to solve American domestic problems, guards were attacking them like animals.’” “teacher” in a word association memory test. Zimbardo ended the experiment after only six days. namely poverty, crime, and urban riots—beginning a series This was the beginning of Philip Zimbardo’s interview The subject of the experiment then witnessed the actor— Claiming that escalating violence merited the termination, of programs to improve urban environments and reinvigorate with England’s Daily Mail, published on August 24, 1971, the supposed fellow participant—strapped into a chair with Zimbardo concluded that the men in the guard group had American communities. three days after Zimbardo electric wires attached to displayed disturbing changes in their personalities and that It was in this context that the Stanford Prison Experiment concluded his now- him, while the subject was those in the prisoner group had psychologically deteriorated. was conducted. Like the assumptions of the Great Society, seminal Stanford Prison While American psychology and set before a control panel Within a decade, the news of these experiments permeated Zimbardo’s experiment sought to demonstrate how envi- Experiment. psychiatry began studying the nature in another room with levers both American medical knowledge and American culture. ronment and social role could dramatically change human Between 1961 and 1971, controlling “shocks” between At his experiment’s outset, Milgram sought to create behavior. American psychologists of evil and the human condition 15 and 450 volts. The control conditions that might demonstrate how and if Americans While American psychology and psychiatry began studying conducted a series of exper- in the 1960s, attempting to panel provided a range of might display the obedience to authority that many citizens the nature of evil and the human condition in the 1960s, iments that transformed the understand the atrocities of World descriptions from “Slight had claimed was their motivation to commit atrocities in Nazi attempting to understand the atrocities of World War II, these way in which the fields of Shock” to “Danger: Severe Germany. experiments were firmly products of the American Cold War psychiatry and psychology War II, these experiments were Shock” to the 435-450 volt Despite the motivation to see if Americans, too, could and Great Society culture. viewed human nature. firmly products of the American levers, ominously labeled commit what the world had decried as acts of evil upon For decades after the publication of these experiments, Since 2018, however, these Cold War and Great Society culture. “XXX.” For each wrong people within their own communities, both the Stanford psychiatry and psychology classes and textbooks portrayed assumptions and the experi- answer, the subject would be Prison Study and the Milgram Experiments are better under- these experiments as shocking views into human nature. But, ments themselves have required to shock the other stood within the context of Cold War America and the Great when looked at from within the American cultural climate been deeply undermined by participant and then increase Society at the end of the 1960s. of this era, these flawed yet influential experiments become a archival research and rare the voltage for subsequent In 1938, the U.S. House Un-American Activities part of something larger: an American history that had often interviews of the subjects of mistakes. Committee (HUAC) began investigating anyone who partici- aggressively sought to learn what evil lurks in the hearts of these studies. Milgram’s findings were pated in “subversive” acts against America as well as suspected men. Although the Stanford sensational. Sixty-five percent communists. Capturing the zeitgeist of the time, mere months In these studies that were foundational for medical and Prison Experiment and the of subjects administered the before the founding of HUAC, a new radio drama took to the psychological understanding of human nature for over half a Milgram Experiments have “XXX” 450-volt shock despite radio waves and its tagline declared: “Who knows what evil century, we are reminded how significantly experimentation been embroiled in recent the increasingly agonized lurks in the hearts of men? The Shadow knows!” and our understanding is influenced by the broader culture controversy, for nearly 60 and pleading screams of the This concept of evil lurking in the hearts of men, and surrounding us. Questions asked in cultural climates of one years these studies indelibly unseen actor in the other investigations to suss out that evil, came to a crescendo in the era may stay with us for decades as experimental fact, leaving transformed the way in Milgram Zimbardo room. No participants refused 1950s with Wisconsin Senator Joseph McCarthy. The second history to haunt us in medical and academic understanding. which human experimen- to administer shocks until just Red Scare in America swept the nation as the U.S. Congress tation is conducted, the before the 300-volt “Extreme began an aggressive attempt to discover what suppos- Author Mary Ellen Leuver is a doctoral candidate in way Americans perceive human nature, and ultimately how Intensity Shock” level. Milgram spent a decade replicating edly insidious ideas lay hidden within any American, from the History of Science & Medicine at Yale University authority as well as social and environmental roles affect what the study in locations further removed from Yale campus, yet Hollywood luminaries to teachers. specializing in bioethics and the history of infectious we came to believe as an inherent human capacity for evil. his findings were nearly identical. It was within this climate that Milgram’s experiments were diseases. She consults on medical history at the University of Maryland School of Medicine. In the basement of a humanities building at Yale A decade later, in the basement of the Stanford psychology conceived. Although McCarthy had been discredited six years University, Stanley Milgram conducted a series of experi- department, Philip Zimbardo intended to conduct a two- before, that studies at this time attempted to unveil what ments on “the effects of punishment on learning.” Within week-long experiment on prison life, enlisting 24 college Americans were capable of under slight external influence is several small, darkened rooms, a psychological subject was students in exchange for $15 a day.
Medicine Bulletin Summer 2019 [28] [29] University of Maryland Medicina Memoriae By Wayne Millan
...the club was honoring Lucille Ball and Desi Arnaz, who were at the height of their fame and commercial success.
Half a dozen of them rushed to the speakers’ platform and offered aid. According to a lengthy report in the daily Variety of November 25, these physicians carried their patient into Doctors in the House a service area behind the dining room, which was located in the Beverly Hilton Hotel. They were said to have worked for at least 20 minutes using a form of the newly-promulgated The Friars Club of when he CPR technique, including artificial respiration and chest Beverly Hills was created in Is there a doctor in the house? came late to 1947 as an offshoot of an the dais that night in an His audience at the Friars Club included older, and still ongoing, club honored place, he showed as much. numerous physicians, which was no with the same name in Manhattan. Following the last of his stories and jokes This newer club’s founders were Milton Berle and other (e.g., “a pretty good club with… several fine judges and surprise since it was a hospital fundraiser. successful entertainers of the immediate post-WWII era, quite a few defendants”), he received a generous round of many of whom were then making their transition into laughs and applause, sat down and fell over into the lap of his compressions. Having failed to get any vital signs by those television from earlier work on stage, on radio, and in neighbor, club founder Milton Berle. Einstein was probably means, Alfred Goldman, MD, chief of surgery at City of Hope film. A Friars Club tradition inherited from New York was in full cardiac arrest even as he slumped, and “Uncle Milty” Hospital, opened the patient’s chest with either a penknife to honor with biting humor, or “roast,” fellow performers at was reported by one source as immediately issuing the hoary or a pocket scalpel. Reports varied: a scalpel seems more lavish dinners. Those dinners also served as fundraisers for various old line, “Is there a doctor in the house?” Based on various probable, and that was in the Variety account. charitable causes including medical care and hospital construction. press accounts, however, it seems likely that Berle was not Goldman and his colleagues began internal heart massage. At a dinner during the Thanksgiving season of 1958, the club was honoring joking and realized right away that it was a serious medical After some minutes of that effort, and again with no signs of Lucille Ball and Desi Arnaz, who were at the height of their fame and emergency. Such is strongly suggested by a Variety journalist respiration or heartbeat, either Goldman or one of the other commercial success. Plates at the dinner cost attendees as much as $200 (c. who was present, Joe Schoenfeld. physicians took a lamp cord—probably 110-volt alternating $1500 in year 2019 terms), and the gathering featured a memorable collection Einstein was known in the industry to have been ill with current on a line that would have likely carried in the range of luminaries from what has later been recognized as a golden age of American some form of cardiovascular disease, and this presumed of 10 or 30 amperes—and attempted to use that powerful popular entertainment. Art Linkletter played host; Tony Martin sang; Milton Berle, weakened condition may have played a role in his failure to current to revive Parkyakarkus. There was still no response. Ed Wynn and George Burns were all present to do their comic bits. Towards the end get a television deal of his own. His wife was reported as close Early on the morning of November 24, some 80 minutes after of the program, a radio comedian named Harry Einstein came to the microphone. by that night with nitroglycerin pills in her purse, although he had delivered his final performance, Harry Einstein was Photo by Glenn Francis of www.PacificProDigital.com Einstein is largely forgotten today, and he never successfully made a move into by the time she reached him, Einstein was ashen in color and pronounced dead by the doctors present. television work; but to those assembled, and to the still-large radio audience of had ceased to breathe. His audience Use of alternating current from ordinary electrical outlets 1958, Einstein was familiar for appearing alongside Eddie Cantor and Al Jolson at the Friars Club included was not uncommon in early experiments with defibrillation, in the 1930s, after which he starred in Meet Me at Parky’s on NBC radio during numerous physicians, which including those of Claude Beck, MD, at Case Western during the ‘40s. His lead character in the radio comedy, Meet Me at Parky‘s was no surprise since it was the 1940s and before that by William Kouwenhoven, MD, “Parkyakarkus,” was an example of the “dialect a hospital fundraiser. at Johns Hopkins. Possible cellular damage caused by these humor” that was once highly popular though now ...[Harry Einstein] starred experiments would hardly have been on the minds of those is often discredited due to its ethnic stereotyping. in Meet Me at Parky’s on treating Harry Einstein, however, as they were concerned Parkyakarkus was supposed to be a Greek-American NBC radio during the ’40s. primarily with “doing whatever was possible” in an era long café owner who scrambled his English along with before DNR orders or durable powers of attorney became his eggs. It was by that moniker that Einstein was His lead character in the radio comedy, commonplace. Their use of CPR, however, may have been familiar nationwide, and to which headlines the “Parkyakarkus,” was an example of based specifically on a shortJAMA article from only months next day referred to him. before: “Mouth-to-Mouth Airway Emergency Artificial Harry Einstein was capable of a broader range of the “dialect humor” that was once Respiration” 1958; 166 (12): 1459-1460. The lead author of performance than he demonstrated on radio, and highly popular... that article, Peter Safar, MD, was then chief of anesthesiology
Medicine Bulletin Summer 2019 [30] [31] University of Maryland Managing Medicina Memoriae Money This offering meant so much to Lucy found me. Now it means nothing. Is it Time to Take Your Life Back from Tech? herself unable to say at Baltimore City Hospital. Safar was born in Austria to a anything given ave you ever been having a family dinner when your five-year-old child family of Czech ethnicity, and many of the earliest efforts what was happening behind the dining asks you to put your phone down? Or a cocktail party where everyone at understanding the electrical functions of the heart were room. Desi got up to the microphone is texting? We’ve all experienced those moments when it feels like done by researchers in that country or in Russia (e.g., and provided some gentle last words: devices have invaded our lives. Some of us may decide it’s time to Naum Gurvich). Safar and his Baltimore colleagues invited “This offering meant so much to H reassess our relationship with technology—but how? It’s a struggle to reap the considerable benefits and avoid the most Hopkins and Maryland medical students to be anesthetized me. Now it means nothing. Please, damaging costs of technology in our lives. One key reason we like our devices so and curarized, enabling the researchers to compare various everyone, pray to your own God much is that they take things off our mind. Technology can act as a kind of second ventilation strategies. Even a year before his JAMA article that he will be saved.” brain, a process known as “cognitive off-loading.” Its basic premise is that humans appeared, in 1957, Safar published a book on the “ABCs” of Audio of Parky’s last night is often take physical actions to reduce the effort of information processing on our Scott D. Canuel, CFA, CFP© CPR that was aimed at a wide audience. He later helped to available on the internet excepting the final brains. Relieved that technology is working on our behalf, we presumably have J.P. Morgan Private Bank design the famous Resusci Anne doll that many readers will few moments when he collapses: [email protected] more time and energy to do other things—whether that’s more work, play, life recall training on: “Annie, Annie, are you all right?” experiences, or family moments. One of the other physicians identified as being at the Disclosures: At J.P. Morgan we’re big believers in data (no surprise there) and in that spirit 1 JP Morgan’s global research was Friars Club dinner that night was Eliot Corday, MD, who had conducted in collaboration with we commissioned global research with 1,500 high-net-worth and ultra-high-net- iResearch. We surveyed 1,500 people commenced a long and distinguished career and later served globally, across 11 areas in North 1 worth participants to explore people’s perspectives on technology. The data clearly America, South America, Europe as president of the American College of Cardiology. Corday and Asia. The population was spread shows that people find value in technology on a deeply personal across a wide range of age groups was already a chief of cardiology at one of the hospitals extraordinary level. But participants express real conflict regarding the amount of time they spend 21–35 (34%), 36–50 (34%), and 51+ that later joined to form Cedars-Sinai Medical Center, yet (32%). Net worth of participants on their devices. (excluding their personal residences) it seems likely that any decisions he made were at least ranged from USD 250,000 to USD How should we balance the pros and cons of technology in our financial lives? 100 million, with 36% between USD approved by Goldman since he was the senior doctor reported 250,000 and USD 1 million, 34% Drawing on the results of our survey, we offer five tips for making technology a between USD 1 million and USD 5 to be present. Modern emergency and trauma care (e.g., million and 30% USD 5 million+. positive force in our lives. This material is for information by Maryland’s own R Adams Cowley, ’44) were only just purposes only. The information provided may inform you of certain starting to be developed in 1958, and there were no reports of Tip 1: Embrace the benefits of technology—from relationships to how you products and services offered by J.P. Morgan’s wealth management an ambulance being summoned that night since doing so was financially transact businesses, part of JPMorgan Chase & Co. (“JPM”). The views and not yet standard practice. Given the continuing reality—over The pace of technological change in cardiology continued Tip 2: Spend your time intentionally—on and off your device strategies described in the material may not be suitable for all investors 60 years later—that a majority of patients administered CPR to be rapid after 1958. Only a year following Einstein’s death, Tip 3: Know the risks of using your device—and share that information with and are subject to risks. This material is confidential and intended for your on an emergency basis do not survive, both Goldman and Morton Mower, ’59, crossed the stage at Maryland. Mower the people you care about personal use. It should not be circu- lated to or used by any other person, Corday may be forgiven for taking the heroic if futile measures is credited as co-inventor of the automatic implantable Tip 4: Beware of cognitive off-loading—in other words, use your gray matter! or duplicated for non-personal use, that they did. cardioverter defibrillator, for which he was honored by the Tip 5: Relocate your phone—depending on your situation or circumstance without our permission. Harry Einstein was married twice and had four sons: school this spring (see page 3). If available during the 1950s So when you pick up your phone for the 20th time that day (after you’ve only all went on to careers in the creative arts or performance. it could perhaps have prolonged the life if not the humor of been up for an hour) ask yourself the question we posed to our survey participants: Clifford Einstein has served as chairman of the Museum of Parkyakarkus as it does for many patients today. Is technology enhancing my life, or disrupting it? We all hope to harness the posi- Contemporary Art in Los Angeles, and the youngest child, tive power of technology in our lives, while avoiding its less attractive side effects. Albert, is well known as an actor, writer and director under Wayne Millan has served for many years as consultant to the University of Maryland Historical Clinico-Pathological By definition, the choice is personal—there is no “correct” answer. And as tech- the name Albert Brooks. He changed his name in early Conference. Since 2010, he has been a lecturer in classics nology evolves, so too will our own personal calculus about what it is we want from adulthood with the excuse that there already was one Albert at The George Washington University, and in collaboration our ever-present smartphones and devices. Einstein and he doubted that he could measure up. with Dr. Victor Weedn of GWU, he is now at work on a first-ever modern translation of the Four Books on Harry Einstein’s time at the microphone was scheduled to Evidence Given by Doctors published in 1602. The come shortly before the evening’s honorees, Lucille Ball and Four Books (“Libri Quatuor”) were written in Latin by a Desi Arnaz, were to receive their awards and offer final toasts. Sicilian physician Fortunato Fedele who was the first known practitioner of forensic pathology.
Medicine Bulletin Summer 2019 [32] [33] University of Maryland Advancement RecoA look back ectionsat America’s fifth oldest medical school and its illustrious alumni Gala Spotlights Victories Achieved by Student Scholarships 205 Years Ago} he vital role that private When it came time to apply for resi- philanthropy plays in dency, Eslami says she knew she would In 1814, Samuel Martin, Class of 1813, made a daring rescue nurturing the growth of today’s be happy to stay at Maryland, but she during the War of 1812. llAs American troops were repelling medical students was on wanted “to see what was out there,” to T display at this year’s medical be confident about her decision. the British during the Battle of North Point in Baltimore, Sgt. school gala held on May 4 at the “I knew it would be expensive to Alexander MacKenzie lay wounded on the battlefield. Martin, Baltimore Convention Center. Katy travel to different states, to stay over- riding horseback, charged in, scooped up MacKenzie and carried Eslami, ’19, recipient of the Carolyn night, to attend full-day interviews,” M. Apple, MD ’90 Scholarship, she says. “I fully planned on taking him to safety. It was during this battle that Major General Robert embodied the spirit of the Gala’s theme, more loans to support these costs.” Ross, commander of the British forces, was mortally wounded. “Vital Signs, Vital Victories.” That’s when she found out she was “If it wasn’t for the generosity of recipient of the Apple Scholarship, people like you, I would not be standing awarded to medical students from the here,” Eslami told the 1,000 guests in eastern shore who have demonstrated attendance. financial need. Eslami, class president who is “To receive a generous scholarship 125 Years Ago remaining at Maryland for a pediatrics and not have debt be a consideration in { residency, says her path to the podium the number of programs that I applied wasn’t exactly linear. to was just the biggest gift I could have In 1894, Thomas C. Gilchrist, MD, described the first case of Blastomycosis Born and raised in Tehran, Iran, received from anybody,” she says. “I will of the skin. His contribution was the identification and isolation of the double- Eslami learned English by watching apply to medical schools, her father was be forever grateful for that.” American children’s TV shows and critically injured at work. Eslami spent Ensuring the future of medicine, contoured spore Blastomyces dermatitidis, identifying the organisms under the movies, often imagining friends the entire month of August with him both at home and around the globe, was microscope and making accurate drawings. Gilchrist held dual appointments as who were “blonde and blue-eyed, while he recovered at Shock Trauma. an important reason for establishing clinical professor of dermatology at Maryland and Johns Hopkins. rode yellow school buses, and drank “They treated my dad with the her scholarship, says Carolyn Apple, Kool-Aid.” When her family immi- utmost respect and compassion—and ’90. A native of Queen Anne’s County, grated to the U.S. and settled on the view from his room was actually the Apple spent her career in internal and Maryland’s eastern shore, however, the admissions office,” she says. “So, I knew emergency medicine, and values the then-16-year-old discovered that her I wanted to end up here, even before I importance of making medical school new life would be far different from applied.” accessible for students from diverse what she envisioned. socio-economic backgrounds, including “America and its people proved to rural and medically underserved areas. me that living and succeeding here America and its people proved “The education I received at required hard work, but that my hard Maryland provided the foundation for Years Ago to me that living and succeeding 90 } work would never go unrecognized,” my life in medicine, from returning she says. here required hard work, but that home to provide medical care to my In 1929, the Medical Alumni An industrious attitude has served Delmarva Peninsula neighbors, to “my hard work would never go Association incorporated and then Eslami well, from discovering a love of caring for victims of natural disasters science in high school to earning dual unrecognized. nationwide, to having a global impact purchased a building across the undergraduate degrees in physiology teaching and mentoring medical street from the old medical building and neurobiology at the University of providers in Tanzania,” says Apple. “I Maryland College Park. Although her family supported her am happy to be in a position to help on Lombard Street where it “I knew I wanted to work with decision to go to medical school, she students from the Eastern Shore as they operated a university bookstore and people, and after volunteering at a knew she would need to find a way begin following their dreams.” cafeteria. To finance the $22,500 hospital, I realized medicine was the to pay for it. As with her undergrad” For more information on supporting perfect way to combine my interests— expenses, she was fortunate to receive student scholarships, contact purchase, six percent secured bonds using science to help people,” she says. several scholarships to help defray costs, Marjorie Bray at 410-706-0418 or were offered to alumni, faculty, and One experience solidified everything paying the remainder through grants [email protected]. friends. in her mind. As she was beginning to and loans.
Medicine Bulletin Summer 2019 [34] [35] classnotes
convocation studentactivities
the largest medical Best Wishes to Class of 2019 practices for female health services in Hagerstown and Degrees were granted to 160 students constituting the University of Maryland School Washington County, of Medicine Class of 2019 in May. Convocation was held at the Hippodrome Theater classnotes Maryland. 1999: on Thursday, May 16. The keynote speaker was Diana W. Bianchi, MD, director of the 1954: Mary Kathleen Deming Endowed Chair in Internal Medicine Stephen T. Woods Eunice Kennedy Shriver National Institute of Child Health and Human Development. 1950s Buetow of Champaign, Ill., and director of the center for translational of Columbus, Ohio, This year’s faculty gold medalist for outstanding qualifications for the practice of received special recognition at gradua- research in infection and inflammation at was elected to the Mitesh B. Kothari, ’95 medicine was Paige F. Kennedy. tion ceremonies in May at the University of Tulane School of Medicine. 1989: Clarita board of directors of During the ceremony retiring associate dean of admissions, Milford M. “Mickey” Illinois College of Medicine at Urbana where Dawson of Glenelg, Md., is division chief Central Ohio Primary Foxwell, ’80, received the dean’s distinguished gold medal, celebrating his career at she served on the faculty since its founding of anesthesiology & critical care medicine Care, the largest physician-owned practice Maryland. in 1972. For several years she was head of at Howard County General Hospital which in the country where he enjoys growing In his address to the class, MAA president Stan Malinow, ’68, thanked Kennedy, pediatrics, and she continues to serve on is affiliated with Johns Hopkins School of the musculoskeletal division as managing Elizabeth Herzog, Eseigboria Ikheloa, Josef Jolissaint, and Christopher Petruccelli for the promotion and executive committees. Medicine. partner. their service on the association’s student advisory council. Buetow extends greeting to all classmates. 1991: Thomas B. Kelso 2000: Matthew Sedgley Diana W. Bianchi, MD, was this year’s 2000s of Frederick, Md., was an keynote speaker. 1969: Ronald L. Schneider 1990s of Southport, N.C., is author 1960s of Somerset, Mass., regrets that of Fractured, a medical thriller available at assistant sports medicine team physician for he was unable to attend the 50th reunion Amazon. 1992: Lawrence Seiden and the Baltimore Orioles during spring training. in spring. His absence was due to illness. wife Beth of Atlanta are soon-to-be empty 2008: Erica M. Richards of Washington, He and wife Ada continue birdwatching and nesters, as son David is about to start D.C., is chair and medical director of ballroom dancing three times a week. They college. Daughter Rachel, born during intern- psychiatry and behavioral health at Sibley have two children, six grandchildren, and ship, lives in Israel and will be married soon, Memorial Hospital which is part of Johns one great-grandchild. while son Ben, born during residency, is an Hopkins Medicine. aerospace engineer with Lockheed Martin. 1971: Michael Maloney of 1995: Mitesh B. Kothari of Hagerstown, 2010s 2011: Marie Shockley of 1970s Cincinnati works four days per Md., was named to the board of directors Atlanta is an assistant profes- week in private practice doing child, ado- for Potomac Bancshares, Inc. Kothari is a sor at Emory University after completing a lescent, and adult psychiatry in a group of partner of Capital Women’s Care, one of minimally invasive gynecologic fellowship at 25 psychiatrists. He vacations in Paris twice the Cleveland Clinic Florida. a year and is looking forward to the 50th reunion in 2021. 1977: Gerald P. Perman of Chevy Chase, Md., recently performed on Our Medical Alumni Association guitar and vocals at the Chinioteague Island Mission: The Medical Alumni Association of to maintain the alumni data base, produce the Blueberry Festival. the University of Maryland, Inc., in continuous quarterly Bulletin magazine, stage social events operation since 1875, is an independent for alumni and students, administer a revolving 1981: Rona Sayetta of 1980s charitable organization dedicated to supporting student loan fund, and oversee conservation of Charlottesville, Va., authored the University of Maryland School of Medicine Davidge Hall and maintain its museum. Careworn: A Memoir. Published by The and Davidge Hall. Oaklea Press under a pseudonym, the book Annual Fund: The association administers the Board Structure: The MAA is governed by a annual fund on behalf of the medical school. Gift chronicles her story of becoming a doc- board consisting of five officers and nine board revenues support student loans and scholar- tor and finding life balance. She is retired members. Each year more than 100 alumni ships, lectureships, professorships, capital from her psychiatry practice in Boca Raton, participate on its seven standing committees and projects—including Davidge Hall conservation— Fla. 1982: Guillermo W. Arnaud of special anniversary class reunion committees. plus direct support to departments for special Norman, Okla., is retired and enjoying the projects and unrestricted support to the dean. golden years. ❖ Constance J. Johnson of Membership: Annual dues are $85. Dues are Chapmansboro, Tenn., has taken up bridge complimentary the first four years after gradua- The Morton M. Krieger, MD, Medical tion and can be extended until the graduate has Alumni Center is located on the second floor in addition to enjoying her horses. She con- completed training. Dues are waived for members of Davidge Hall, located at 522 W. Lombard tinues at a volunteer charity clinic. ❖ Allan MAA president Stan Malinow, ’68, welcomed the class to the alumni association. reaching their 50th graduation anniversary or Street, Baltimore, MD, 21201-1636, telephone Jay Raskin of Wakefield, R.I., continues have turned 70 years of age. Revenues sup- 410.706.7454, fax 410.706.3658, website working in an ER and also serves one day Paige F. Kennedy received the faculty gold medal. port salaries for two full-time and five part-time www.medicalalumni.org, and email each week in a Suboxone clinic. 1985: employees, as well as general office expenses [email protected]. Jay Kolls of Mandeville, La., is the John W.
Medicine Bulletin Summer 2019 [36] [37] University of Maryland
in memoriam !@
in memoriam Memorial gifts are warmly received by: !@ Medical Alumni Association of the Edward V. Spudis, ’53 outstanding contributions to medicine and Robert W. Hertzog, ’67 Dr. Buckler trained in general surgery University of Maryland, Inc. Neurology distinguished service to mankind. He was Pathology and anatomic/clinical pathology. From 522 West Lombard Street Winston-Salem, N.C. G. Edward Reahl, ’56 an active member of the Church of Jesus East Aurora, N.Y. 1971 to 1978, he served as a captain in Baltimore, Maryland, 21201-1636, March 25, 2019 Orthopaedic Surgery Christ of Latter-day Saints and enjoyed April 15, 2019 the U.S. Army Reserves, primarily with or for more information Baltimore skiing. Preceded in death by wife Lucy, the 100th MASH Hospital. From 1978 simply call 410.706.7454. Prior to medical school, Dr. Spudis joined March 30, 2019 Upon graduation Dr. Hertzog joined the the U.S. Army and later served with the daughter Mary, and two grandchildren, U.S. Army Medical Corps, interning and to 1997, Buckler was a pathologist and Engineer Corps in occupied Japan. Upon Mercy Hospital in Baltimore was the loca- Hickman is survived by five children, 17 receiving residency training at the Walter later chairman of Kent General Hospital medical school graduation he interned at tion of Dr. Reahl’s internship, followed by grandchildren, and 40 great-grandchildren. Reed General Hospital in Washington, in Delaware, also serving on the boards He was a member of the pre-hospital Detroit Receiving Hospital and remained one year as an assistant surgical resident D.C. This was followed by a fellowship at of the county and state medical societies. committee that started a helicopter service Lewis H. Richmond, ’58 in Detroit for residency training at the VA there. He then traveled to the Hospital the Armed Forces Institute of Pathology. He enjoyed photography, fishing, hunting, out of Mercy 1. In 1989, Posey received the Psychiatry Hospital. Spudis continued post-graduate for Joint Diseases in New York City for a In 1975, Hertzog was promoted to the scuba diving, and training and competing State of Iowa Governor’s Volunteer Award. San Antonio, Tex. training at the Mayo Clinic in Rochester, six-month orthopaedic pathology resi- rank of lieutenant colonel and became with his Labrador Retrievers. Survivors He enjoyed pistol shooting, reading, golf August 19, 2018 Minnesota, serving a neurology fellowship dency, followed by a three-year residency chief of forensic pathology at the insti- include wife Wendy and one daughter. and woodworking. Wife Lynn survives him. and earning an MS degree in electro- and fellowship at New York Orthopaedic Upon graduation, Dr. Richmond interned tute. He was an expert in the pathology Joshua Frankel, ’71 Faculty encephalography. In 1958, he relocated Hospital and Columbia Presbyterian at Brooke Army Medical Center and after of accidents and missile trauma, serving Ophthalmology to Winston-Salem, joining the faculty at Medical Center. From 1962 to 1964, he taking a course in aerospace medicine on the faculties of Howard University, Edmund M. Glaser, PhD Los Angeles Bowman Gray School of Medicine where served in the U.S. Navy, stationed at the completed residency training at Walter Georgetown University Law Center, and May 16, 2019 July 5, 2017 for more than 30 years he served on the U.S. Naval Hospital in St. Albans, N.Y. He Reed General Hospital in Washington, George Washington University as an Dr. Glaser was a professor in the depart- faculty teaching, conducting research, and was honorably discharged with the rank of D.C. For 13 years, he was a flight surgeon assistant professor of pathology. Hertzog Dr. Frankel practiced ophthalmology in Los ment of physiology from 1972 until seeing neurology patients in the clinic and lieutenant commander. Reahl returned to and physician in the U.S. Air Force, rising retired from the Medical Corps in 1976 and Angeles and is survived by wife Sarah. retirement in 1995. Born and raised EEG lab. He also practiced privately from Baltimore after his military service to prac- to the rank of major before his honor- relocated to East Aurora where he held in New York City, Glaser attended The 1965 until retirement in 1989. In retire- tice privately and from 1967 to 1993 served able discharge. Richmond attended several laboratory directorships and was Stanford J. Huber, ’71 Cooper Union as an electrical engineering ment he provided neurology services at as chief of orthopaedics at Mercy Medical the San Antonio Group Psychotherapy an assistant clinical professor of pathology Anesthesiology major during World War II when he was the Rehabilitation Department of Forsyth Center. He retired in 2003. Reahl was a Institute from 1967 to 70 and became at the University of Buffalo Jacobs School Morgantown, W.Va. drafted into the U.S. Army. He served in Medical Center, the VA Clinic, and the member of the 1807 Circle of the John board certified in psychiatry/neurology. of Medicine. He retired in 2011. Hertzog May 29, 2019 Nuremberg as a motion picture sound Community Care Center Free Clinic. He Beale Davidge Alliance, Maryland’s society He practiced privately, specializing in enjoyed reading about science and history, South Baltimore General Hospital and photographer for the medical war trials fully retired in 2005. Spudis enjoyed for major donors. He supported Baltimore adolescents. Richmond had a passion for acquiring an extensive collection of books. the University of Alabama were the loca- of German Nazi physicians. After military sculpting, computer programming, and arts and sports teams, enjoyed playing local theater and later in life fulfilled his Preceded in death by wife Florence, he is tions of Dr. Huber’s training. He was a service, he completed his bachelor’s playing a number of musical instruments. bridge, and was a collector of antiques dream of performing stand-up comedy in survived by two sons, one daughter, and flight surgeon with the U.S. Air Force in degree and began working with commu- Survivors include wife Martha, three daugh- and art. Reahl was preceded in death by San Antonio and New York City. Survivors five grandchildren. San Antonio, Texas, rising to the rank of nications systems and guided missiles for ters, and five grandchildren. wife Nancy and son G. Edward Reahl, III. include wife Barbara, three children, and lieutenant colonel before his honorable the U.S. Air Force. Attracted to the new Survivors include four children, 13 grand- five grandchildren. Bruce J. Bowen, ’68 discharge. He practiced anesthesiology fields of computers, information theory, J. Edward Kelly, Jr., ’56 children, and one great-grandson. Diagnostic Radiology at West Virginia University Ruby Hospital and artificial intelligence, Glaser returned Internal Medicine & General Surgery James H. Tyer, ’58 Washington, D.C. and then went into private practice. Huber to school, receiving a PhD from Johns Robert O. Hickman, ’57 Syracuse, N.Y. Obstetrics & Gynecology November 16, 2018 enjoyed camping, hiking, and fly-fishing. Hopkins University and shortly thereafter Pediatric Nephrology March 15, 2019 Stoughton, Mass. He was preceded in death by wife Joan joined Maryland’s faculty in the depart- Woodway, Wash. Dr. Bowen interned at St. Luke’s Hospital March 23, 2019 and daughter Jennifer and is survived by ment of physiology. In collaboration with Dr. Kelly’s internship and residency training April 4, 2019 Center and received residency training in in Baltimore were interrupted when he was St. Vincent’s Hospital in New York City diagnostic radiology at Columbia University four sons, five grandchildren, and one Dr. Hendrik Van der Loos at Johns Hopkins, commissioned as an officer in the U.S. Dr. Hickman interned at the University of was the location of Dr. Tyer’s internship, College of Physicians and Surgeons. He great-granddaughter. they studied the morphology of the brain’s Navy. He returned to complete training in Utah and received residency training in followed by two years with the U.S. Navy practiced in Washington, D.C., and was cerebral cortex. It was during this time that 1963 as he was honorably discharged as pediatrics at the University of Washington. serving as a medical officer with duties in managing physician at Washington Imaging Guy H. Posey, ’80 they formulated the design and construc- a lieutenant commander. Afterwards Kelly He remained at the University of San Diego. After military service, he received Associates, providing radiology services to Emergency Medicine tion of the first computer microscope. returned to Syracuse—his birthplace—to Washington for a pediatric nephrology residency training at St. Margaret’s Hospital Health South Diagnostic. In 1998, Bowen Sioux City, Iowa The two are credited with coining the set up a private practice where he remained fellowship from 1960 to 1962 and was and New England Medical Center in Boston. received its outstanding medical contribu- March 6, 2019 term “computer microscopy.” Glaser later until retirement. He was also an assistant involved in placing the first child in the From 1964 until retirement in 1997, Tyler tions award. He also held affiliations with After training in family medicine in Sioux invented a computer microscope named attending at Community General Hospital. world on both long-term hemodialysis maintained a solo OB/GYN practice, holding Howard County General, Gladys Spellman City, Dr. Posey practiced for four years Neurolucida that combined all aspects of Throughout his career Kelly was very active and home hemodialysis. Hickman later privileges at Goddard Hospital in Brockton Specialty, and Sibley Memorial Hospitals. before moving into emergency medicine. computer microscopy into a single instru- in his local community. Preceded in death developed a catheter used widely by cancer where he delivered more than 5,000 babies. Survivors include finance Rowena Gerber, He worked at both hospitals in Sioux City ment. It became known for its ability to by wife Sheila and two children, he is patients to deliver intravenous nutrition Upon retirement he spent winters in Hilton two children, and one grandchild. including 34 years at Unity Point-St. Luke’s. significantly enhance neuroanatomical survived by five children including Margaret and chemotherapy as well as for blood Head, S.C. He enjoyed golf, travel, reading, Posey was instrumental in starting the para- research. Glaser was preceded in death by Burkhead, ’97, six grandchildren, and one draws. The Medical Alumni Association cooking, listening to music, and spending Leroy B. Buckler, ’71 medic program for the city and for 18 years wife Freda and granddaughter Sophia, and great-grandson. recognized his career achievements by time with family. Preceded in death by wife Surgery, Anatomic/Clinical Pathology was volunteer medical director for all emer- is survived by two sons, one daughter, and naming Hickman recipient of the 2007 Lucille, Tyer is survived by seven children Madison, Md. gency medical and paramedic programs. two grandchildren. Honor Award & Gold Key, presented for and eight grandchildren. April 18, 2019
Medicine Bulletin Summer 2019 [38] [39] University of Maryland PLANNED GIVING Your LEGACY...
“I owe my medical career it’s and achievements to the Personal University of Maryland Siblings Miriam Cohen and Jack Lichtenstein stayed close to their School of Medicine.” childhood Pikesville home for their medical education at the University of —Miriam L. Cohen, MD ’64 Maryland School of Medicine. As Dr. Cohen pursued her life-long dream to be a cardiologist, Dr. Lichtenstein followed in her footsteps for his training, finding his calling in rheumatology. They each credit the School of Medicine with their success and are both giving back with their bequest gifts. Their philanthropic legacy will advance the School’s mission to help others through outstanding service to the community. How will you inspire others with your legacy? Legacy gifts to the University of Maryland Baltimore Foundation cost nothing up front. Whether your beneficiary designation is through your will, IRA, pension plan, a Charitable Gift Annuity (CGA), or life insurance policy, your gift is customizable and adaptable to changing financial situations. Your gift can: • build an endowment; • provide scholarships; • support faculty; • support the School of • advance research; Medicine’s other critical needs.
Whatever form your legacy gift takes, you can have an impact on the future of medicine. “Medical school taught me For more information about bequests, gifts that pay income for life, and that I could do something other innovative ways to support the School of Medicine, please good and practical in this visit: www.umbfplannedgiving.org. world. It is time for me to Or contact: give back.” Marjorie Bray —Jack R. Lichtenstein, MD ’67 Director of Development, Alumni University of Maryland School of Medicine 410-706-0418 [email protected]
*PLEASE NOTE: Legacy gifts should be made payable to the University of Maryland Baltimore Foundation, Inc., for the benefit of the University of Maryland School of Medicine. 1,000 Pancreas Transformative Transplants and Treatments in Counting Stroke Care
Reshaping treatment for diabetes UMMC Remains One of Nation’s Top mellitus and end-stage renal disease Comprehensive Stroke Centers
The University of Maryland Medical Center is among the most While pancreas transplant volumes across the nation are experienced in mechanical thrombectomies for stroke patients - a decreasing, the University of Maryland Medical Center numbers key requirement for comprehensive stroke centers - due to its higher have steadily increased thanks to its multidisciplinary approach acuity volumes, expert faculty-physicians, extensive resources and to treating diabetes mellitus and end-stage renal disease. Using a INTRODUCING: multidisciplinary approach to patient care. comprehensive evaluation and educational process helps identify Seemant Chaturvedi, MD Professor of Neurology patients who could benefit from simultaneous pancreas-kidney In the case of a major stroke, the therapeutic time window in which Director, Stroke Division – (SPK) more than standard kidney transplant alone. emergent care such as mechanical thrombectomies must be delivered to Neurology prevent disability or mortality recently expanded from within a six-hour Medical School: University • Patients wait a fraction of the time. Using SPK as a standard window to up to 24 hours for certain acute stroke patients. With four of Connecticut School of therapy for eligible patients with ESRD and DM can decrease board-certified neurointerventional specialists on call 24/7 to evaluate Medicine wait times from an average of 6 years for a kidney alone to 90 and perform this complicated procedure, the UMMC team provides: days for an SPK. Internship: St. Francis Hospital • Shorter hospital stays, with nearly half of all thrombectomy patients University of Massachusetts • SPK can treat both Type I and Type II Diabetes. Formerly discharged in two to three days Residency: Medical Center #1 in the nation thought of as a treatment for only Type I DM, SPK can benefit • Decreased risk of infection and complications for simultaneous properly selected Type II patients and nearly all remain free of Fellowship: University of Western pancreas-kidney insulin after transplantation. Ontario - Neurology, Stroke To refer a patient for comprehensive transplants in The University of Maryland Transplant Center has also established a Research Interests: Carotid and multidisciplinary approach to cardiac clearance for this challenging stroke care, please call 410-328-4323. intracranial atherosclerosis, gender differences in stroke, stroke in 2018* population. Using advanced non-invasive cardiac testing minimizes young adults the need for cardiac catheterization and expedites cardiac clearance for surgery.
To refer a patient or New and #1 in the region consult with one of our physicians, call effective for solitary 410-328-2864. Better treatments pancreas outcomes transplants in Learn more at umm.edu/pancreas Visit our Physician Briefs at physicians.umm.edu for stroke Learn more at umm.edu/stroke 2018* patients Visit our Physician Video Channel at physicians.umm.edu * Based on volume data as of May 2019, Organ Procurement and Transplant Network, www.optn.transplant.hrsa.gov Nonprofit U.S. Postage PAID Medical Alumni Association Baltimore, MD of the University of Maryland, Inc. Permit No. 3800 Morton M. Krieger, MD, Medical Alumni Center 522 West Lombard Street Return Service Requested Baltimore, MD 21201-1636 www.medicalalumni.org
MEDICINE
BuSummer 2019etin
reunion Mark your calendars! 2020 145th Medical Alumni Reunion May 1-2, 2020 Classes celebrating milestone reunions include: 1955, 1960, 1965, 1970, 1975, 1980, 1985, 1990, 1995, 2000, 2005, 2010, 2015