Anti-RTN1 monoclonal antibody, clone NPO271 (DCABH-10180) This product is for research use only and is not intended for diagnostic use.

PRODUCT INFORMATION

Product Overview Mouse monoclonal to Reticulon 1A

Antigen Description Reticulon 1A may be involved in neuroendocrine secretion or in membrane trafficking in neuroendocrine cells. It is expressed in neural and neuroendocrine tissues and cell cultures derived therefrom. Expression of isoform RTN1-C is strongly correlated with neuronal differentiation. Different isoforms have been described as a result of alternative splicing.

Specificity This antibody exclusively recognizes the 135 kDa Reticulon-1A in immunoblots of NCI- H82 and other SCLC cell lines, and stains normal and pathological neural and neuroendocrine tissues

Immunogen Partially purified bacterially expressed Reticulon-1A (NSP-A) hybrid protein (beta-GAL-NSP-A 6- 776).

Isotype IgG1

Source/Host Mouse

Species Reactivity Human

Clone NPO271

Purity Protein G purified

Conjugate Unconjugated

Applications IHC-P, Flow Cyt, ICC, IHC-Fr, WB

Format Liquid

Size 100 μg

Buffer Preservative: 0.09% Sodium Azide; Constituents: PBS

Preservative 0.09% Sodium Azide

Storage Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

45-1 Ramsey Road, Shirley, NY 11967, USA Email: [email protected]

Tel: 1-631-624-4882 Fax: 1-631-938-8221 1 © Creative Diagnostics All Rights Reserved INFORMATION

Gene Name RTN1 reticulon 1 [ Homo sapiens ]

Official Symbol RTN1

Synonyms RTN1; reticulon 1; neuroendocrine specific protein , NSP; reticulon-1; neuroendocrine-specific protein; NSP; MGC133250;

Entrez Gene ID 6252

Protein Refseq NP_066959

UniProt ID Q16799

Chromosome Location 14q21-q22

Function signal transducer activity;

45-1 Ramsey Road, Shirley, NY 11967, USA Email: [email protected]

Tel: 1-631-624-4882 Fax: 1-631-938-8221 2 © Creative Diagnostics All Rights Reserved