Biological Sciences Subject Index Proc. NatL Acad. Sci. USA 81 (1984) 8101

5-Methyltryptophan Middle T Characterization of the Bacillus subtilis tryptophan promoter region, 6315 obl7 cells transformed by the middle-T-only of polyoma virus Metric analysis differentiate in vitro and in vivo into adipose cells, 5440 Internal duplication in human a, and Al interferons, 7171 Mik Mevalonolactone A bombesin immunoreactive peptide in milk, 578 In vivo modulation of rat liver 3-hydroxy-3-methylglutaryi-coenzyme A Evidence for physiological function of epidermal growth factor: reductase, reductase kinase, and reductase kinase kinase by Pregestational sialoadenectomy of mice decreases milk production and mevalonolactone, 7293 increases offspring mortality during lactation period, 6059 Mevinolin Milliped Inhibition of 3-hydroxy-3-methylglutaryl-CoA reductase by mevinolin in Spider sedation induced by defensive chemicals of milliped prey, 806 familial hypercholesterolemia heterozygotes: Effects on cholesterol Mini-Mu-ac bacteriophage balance, 2538 In vivo DNA cloning and adjacent gene fusing with a mini-Mu-Iac Hydroxymethylglutaryl-coenzyme A reductase-containing hepatocytes are bacteriophage containing a plasmid replicon, 1480 distributed periportally in normal and mevinolin-treated rat livers, 5556 Miniature endplate current Micelle Diffusion and binding constants for acetylcholine derived from the falling Role of membrane lipids in peptide hormone function: Binding of phase of miniature endplate currents, 1594 enkephalins to micelles, 61 Mlnichromosome Microbody transition Minichromosomal repetitive DNA in Trypanosoma cruzi: Its use in a Maturation of catalase precursor proceeds to a different extent in high-sensitivity parasite detection assay, 3356 glyoxysomes and leaf peroxisomes of pumpkin cotyledons, 4809 Mink cell focus-forming virus Microcapsule Viral integration near c-myc in 10-20%o of MCF 247-induced AKR Long-acting delivery systems for peptides: Inhibition of rat prostate lymphomas, 6808 tumors by controlled release of [D-Trp6]luteinizing hormone-releasing Misonidazole hormone froth injectable microcapsules, 5845 Nitroaromatic radiation sensitizers substitute for oxygen in Microfilament neocarzinostatin-induced DNA damage, 3312 Intermediate filaments in monkey kidney TC7 cells: Focal centers and Mitochondria interrelationship with other cytoskeletal systems, 1117 Steps in processing of the mitochondrial cytochrome oxidase subunit I P2- pre-mRNA affected by a nuclear mutation in yeast, 8 Weak HLA and 62-microglobulin expression of neuronal cell lines can be Single catalytic site model for the oxidation of ferrocytochrome c by modulated by interferon, 6476 mitochondrial cytochrome c oxidase, 347 Microinjection Pronounced structural similarities between the small subunit ribosomal Microinjected pBR322 stimulates cellular DNA synthesis in Swiss 3T3 RNA of wheat mitochondria and , 493 cells, 400 Evidence for the involvement of coupling factor B in the H' channel of Artifacts caused by cell microinjection, 1426 the mitochondrial H+-ATPase, 1371 Introduction of a selectable gene into different animal tissue by a Relationship between lateral diffusion, collision frequency, and electron retrovirus recombinant vector, 7151 transfer of mitochondrial inner membrane oxidation-reduction Microsomal membrane components, 2606 Determinants for protein localization: 3-Lactamase signal sequence Intramitochondrial movement of adrenal sterol carrier protein with directs globin across microsomal membranes, 456 cholesterol in response to corticotropin, 2970 Signal recognition particle is required for co-translational insertion of The [poky] mutant of Neurospora contains a 4-base-pair deletion at the 5' cytochrome P-450 into microsomal membranes, 3361 end of the mitochondrial small rRNA, 3791 Nonenzymic ADP-ribosylation of specific mitochondrial Microsome polypeptides, 3929 On the amino acid sequence of cytochrome P-450 isozyme 4 from rabbit Intracellular targeting and import of an FI-ATPase /3-subunit-p3- liver microsomes, 4260 galactosidase hybrid protein into yeast mitochondria, 3983 Microtubule Molecular cloning and nucleotide sequence of cDNA for mRNA of Interference of GTP hydrolysis in the mechanism of microtubule mitochondrial cytochrome P450(SCC) of bovine adrenal cortex, 4647 assembly: An experimental study, 771 Two nuclear mutations that block mitochondrial protein import in Lysosomes are associated with microtubules and not with intermediate yeast, 4819 filaments in cultured fibroblasts, 788 Isolation and characterization of a cDNA clone for bovine cytochrome c Intermediate filaments in monkey kidney TC7 cells: Focal centers and oxidase subunit IV, 6295 interrelationship with other cytoskeletal systems, 1117 Amino acid sequence of bovine heart coupling factor 6, 6603 Tubulins from different higher plant species are immunologically Yeast mitochondrial genomes consisting of only A-T base pairs replicate nonidentical and bind colchicine differentially, 1440 and exhibit suppressiveness, 7156 Axonal transport of a subclass of T : Evidence for the regional Molecular cloning and nucleotide sequence of cDNA for rat ornithine differentiation of microtubules in neurons, 1570 Imbalance of total cellular nucleotide pools and mechanism of the carbamoyltransferase precursor, 7412 colchicine-induced cell activation, 2401 Mitochondrial complex HI Multinucleation-induced improvement of the spreading of transformed Sequence and structural similarity between cytochrome b of cells on the substratum, 3098 mitochondrial complex III and the chloroplast b64complex: Position of Antagonism by taxol of effects of microtubule-disrupting agents on the cytochrome b in the membrane, 674 lymphocyte cAMP and cell function, 3496 Mitochondrial DNA Relationships between the structures of taxol and baccatine III Mitochondrial gene flow, 1764 derivatives and their in vitro action on the disassembly of mammalian Extensive and widespread homologies between mitochondrial DNA and brain and Physarum amoebal microtubules, 4090 chloroplast DNA in plants, 1946 Dimethyl sulfoxide can initiate cell divisions of arrested callus protoplasts Natural interspecies transfer of mitochondrial DNA in amphibians, 5802 by promoting cortical microtubule assembly, 5449 Mitochondrial gene Phase changes at the end of a microtubule with a GTP cap, 5772 Mitochondrial gene flow, 1764 Involvement of the carboxyl-terminal domain of tubulin in the regulation Mitogen of its assembly, 5989 Purification and characterization of acidic fibroblast growth factor from Introductory analysis of the GTP-cap phase-change kinetics at the end of bovine brain, 357 a microtubule, 6728 Mitogenesis Microtubule-associated protein Inhibition of epidermal growth factor-induced mitogenesis by amiloride Axonal transport of a subclass of r proteins: Evidence for the regional and an analog: Evidence against a requirement for Na+/H+ differentiation of microtubules in neurons, 1570 exchange, 6762 Heterogeneity of microtubule-associated protein 2 during rat brain Mitogenic protein development, 5613 Identification of a 34,000-dalton mitogenic protein associated with plasma High-affinity binding of the regulatory subunit (R ) of cAMP-dependent membranes from human A431 epidermoid carcinoma cells, 3399 protein kinase to microtubule-associated and oiler cellular Mitosis proteins, 6723 Localization of RNA polymerase I in interphase cells and mitotic Microtubule-associated protein 2: Monoclonal demonstrate the by light and electron microscopic selective incorporation of certain epitopes into Alzheimer immunocytochemistry, 1431 neurofibrillary tangles, 7941 Nerve growth factor inhibits the synthesis of a single-stranded DNA Microtubule organixing center binding protein in pheochromocytoma cells (clone PC12), 2080 Phosphoproteins are components of mitotic microtubule organizing Phosphoproteins are components of mitotic microtubule organizing centers, 4439 centers, 4439 Microvilli Target polypeptide of a carcinogen is associated with normal mitosis and Ca2+-ATPase of the sarcoplasmic reticulum shares a common domain carcinogen-induced hyperplasias in adult hepatocytes, 6738 with a membrane associated with the cytoskeleton of Mitoxantrone microvilli, 1130 Condensation of nucleic acids by intercalating aromatic cations, 7368 Microvillin Mixed connective tissue disease Microvillin: A 200-kilodalton protein in microvilli of rat mammary cells Pulse labeling of small nuclear ribonucleoproteins in vivo reveals distinct detected by a monoclonal , 5459 patterns of antigen recognition by human autoimmune antibodies, 3185 Midbrain Mixed-mating model Cerebellum mediates modality-specific modulation of sensory responses Estimation of mating system parameters when outcrossing events are of midbrain and forebrain in rat, 2917 correlated, 5258 8102 Biological Sciences Subject Index Proc. NatL. Acad. Sci. USA 81 (1984)

Mobile genetic element Identification of novel neural- and neural retina-specific antigens with a Sequences homologous to P elements occur in Drosophila monoclonal antibody, 2260 paulistorum, 6794 Immunological evidence for the in vivo occurrence of (2'- Modeling 5')adenylyladenosine oligonucleotides in eukaryotes and Biological system interactions, 2938 prokaryotes, 2322 Modulated receptor hypothesis Inhibition of the mitogenic effects of plasma by a monoclonal antibody to Nitrendipine block of cardiac calcium channels: High-affinity binding to somatomedin C, 2389 the inactivated state, 6388 Isolation of hybridomas expressing a specific heavy chain variable region gene segment by using a screening technique that detects mRNA Mold sequences in whole cell lysates, 2470 Cross-reactions of polysaccharides of fungi, molds, and yeasts in anti- Characterization of monoclonal antibodies to serum pneumococcal and other antisera, 5247 galactosyltransferase, 2529 Molecular dock Organization of collagen types I and V in the embryonic chicken cornea: The molecular clock may be an episodic clock, 8009 Monoclonal antibody studies, 2791 Molecular evolution Disappearance and reappearance of B cells after in vivo treatment with Coding nucleotide sequence of 3-methylcholanthrene-inducible monoclonal anti-I-A antibodies, 2855 cytochrome P450d cDNA from rat liver, 1649 Monoclonal antibodies to native noncollagenous bone-specific Molecular cloning and nucleotide sequence of cDNA for mRNA of proteins, 2868 mitochondrial cytochrome P-450(SCC) of bovine adrenal cortex, 4647 Production of human monoclonal IgG antibodies against Rhesus (D) Guinea pig preproinsulin gene: An evolutionary compromise?, 5046 antigen, 3214 Distinct organization of methylcholanthrene- and phenobarbital-inducible Tumors undergoing rejection induced by monoclonal antibodies of the cytochrome P-450 genes in the rat, 5066 IgG2a isotype contain increased numbers of activated for Molecular motion a distinctive form of antibody-dependent cytolysis, 3506 Interactions of myristic acid with bovine serum : A '3C NMR Method to map antigenic determinants recognized by monoclonal study, 3718 antibodies: Localization of a determinant of virus neutralization of the Molecular orbital feline leukemia virus envelope protein gp70, 3675 Charge state of His-57-Asp-102 couple in a transition state analogue- A monoclonal anti-DNA antibody also binds to cell-surface trypsin complex: A molecular orbital study, 6266 protein(s), 3843 Molecular weight Monoclonal antibodies to purified muscarinic receptor display agonist-like Functional molecular weight of the lac carrier protein from Escherichia activity, 4331 coli as studied by radiation inactivation analysis, 1021 Monoclonal antibodies as probes for unique antigens in secretory cells of Mollusc mixed exocrine organs, 4419 Isolation and identification of enkephalins in pedal ganglia of Mytilus Identification and characterization of a monoclonal antibody to an antigen edulis (Mollusca), 955 expressed on activated macrophages, 4505 Monoclonal antibodies against murine j interferon, 4515 Molluscan cardioexcitatory peptide Use of monoclonal antibodies as sensitive and specific probes for The goldfish nervus terminalis: A luteinizing hormone-releasing hormone biologically active human y-interferon, 5219 and molluscan cardioexcitatory peptide immunoreactive olfactoretinal Monoclonal antibodies of predefined specificity detect activated ras gene pathway, 940 expression in human mammary and colon carcinomas, 5227 Moloney murine leukemia virus Detection of a pancreatic cancer-associated antigen (DU-PAN-2 antigen) Rearrangement of a DNA sequence homologous to a cell-virus junction in serum and ascites of patients with adenocarcinoma, 5242 fragment in several Moloney murine leukemia virus-induced rat Microvillin: A 200-kilodalton protein in microvilli of rat mammary cells thymomas, 38 detected by a monoclonal antibody, 5459 Construction of mutants of Moloney murine leukemia virus by Monoclonal antibody specific for the mutant PiZ a1-antitrypsin and its suppressor-linker insertional mutagenesis: Positibns of viable insertion application in an ELISA procedure for identification of PiZ gene mutations, 4149 carriers, 5690 High-efficiency gene transfer into mammalian cells: Generation of helper- Production and characterization of monoclonal antibodies with specificity free recombinant retrovirus with broad mammalian host range, 6349 for the S1003 polypeptide of brain S100 fractions, 6034 Moloney murine sarcoma virus Monoclonal antibodies against the voltage-sensitive Na+ channel from Frequent generation of nonrescuable reorganized Moloney murine mammalian skeletal muscle, 6227 sarcoma viral genomes, 294 Monoclonal antibodies distinguish subtypes of retinal horizontal Molybdenum- protein cells, 6255 H2-uptake activity of the MoFe protein component of Azotobacter Somatic cell genetic analysit of human cell surface antigens: vinelandii nitrogenase, 376 Chromosomal assignments and regulation of expression in rodent- Monensin human hybrid cells, 6437 Monensin prevents terminal glycosylation of the N- and O-linked Characterization of nerve growth factor receptor in neural crest tumors oligosaccharides of the HLA-DR-associated invariant chain and inhibits using monoclonal antibodies, 6681 it dissociation from the a-X chain complex, 1287 Regulation of T-cell function by antibodies: Enhancement of the response Monensin-induced inhibition of cell spreading in normal and dystrophic of human T-cell clones to hepatitis B surface antigen by antigen- human fibroblasts, 4960 specific monoclonal antibodies, 6846 Na+-H+ exchange in gastric glands as measured with a cytoplasmic- Monoclonal antibodies and peptide mapping reveal structural similarities trapped, fluorescent pH indicator, 7436 between the subunits of the glycine receptor of rat spinal cord, 7224 Monkey cell Monoclonal antibodies to human type IV collagen: Useful reagents to Identification of a higher molecular weight DNA polymerase a catalytic demonstrate the heterotrimeric nature of the molecule, 7343 polypeptide in monkey cells by monoclonal antibbdy, 7777 High-affinity monoclonal antibodies for aflatoxins and their application to Monoclonal antibody solid-phase immunoassays, 7728 Monoclonal antibodies to human urokinase identify the single-chain pro- Identification of a higher molecular weight DNA polymerase a catalytic urokinase precursor, 110 polypeptide in monkey cells by monoclonal antibody, 7777 Human anti-idiotype antibodies in cancer patients: Is the modulation of Immunization in vitro and production of monoclonal antibodies specific to the immune response beneficial for the patient?, 216 insoluble and weakly immunogenic proteins, 7897 Cell surface antigens of human bladder cancer defined by mouse Microtubule-associated protein 2: Monoclonal antibodies demonstrate the monoclonal antibodies, 224 selective incorporation of certain epitopes into Alzheimer Monoclonal antibodies detect the conservation of muscarinic cholinergic neurofibrillary tangles, 7941 receptor structure from Drosophila to human brain and detect possible A noncholinergic site-directed nionoclonal antibody can impair agonist- structural homology with a1-adrenergic receptors, 272 induced ion flux in Torpedo californica acetylcholine receptor, 7999 Cell surface antigens of human ovarian and endometrial carcinoma Monocular deprivation defined by mouse monoclonal antibodies, 568 Labile nature of the visual recovery promoted by reverse occlusion in Monoclonal antibodies detect a spectrin-like protein in normal and monocularly deprived kittens, 286 dystrophic human skeletal muscle, 776 Effects of monocular deprivation on the lateral geniculate nucleus in a Characterization of a membrane antigen from rabbit testis and sperm prinlate, 2255 isolated by using monoclonal antibodies and effect of its antiserum on fertility, 857 Divergence in cholesterol biosynthetic rates and 3-hydroxy-3- Murine monoclonal antibody to a single protein neutralizes the infectivity methylglutaryl-CoA reductase activity as a consequence of granulocyte of human cytomegalovirus, 876 versus monocyte- differentiation in HL-60 cells, 894 Developmental regulation of cytokeratins in cells of the rat mammary Interaction between endotoxin and human : Characteristics of gland studied with monoclonal antibodies, 1203 the binding of 3Hdlabeled lipopolysaccharide and 51Cr-labeled lipid A Monoclonal antibodies against the rat liver glucocorticoid receptor, 1609 before and after the induction of endotoxin tolerance, 3491 Monoclonal antibodies specific for a murine cyt6toxic T-lymphocyte Recombinant human y-interferon induces human monocyte polykaryon clone, 1799 _ formation, 4554 Shared idiotopes among monoclonal antibodies specific for AIPRI8/34 Cytomegalovirus infects human lymphocytes and monocytes: Virus (H1N1) and X-31(H3N2) influenza viruses, 1809 expression is restricted to immediate-early gene products, 6134 Stimulation of human granulocyte function by monoclonal antibody Monocytes are required to trigger Ca2+ uptake in the proliferative WEM-G1, 1818 response of human T lymphocytes to Staphylococcus aureus protein Growth control in cultured 3T3 fibroblasts: Neutralization and A, 6827 identification of a growth-inhibitory factor by a monoclonal Nucleotide sequence of human monocyte interleukin 1 precursor antibody, 2107 cDNA, 7907 Hepatitis B viral antigenic structure: Signature analysis by monoclonal Monod-Wyman-Changeux model radioimmunoassays, 2237 Order of free energy couplings between ligand binding and protein subunit association in , 7098 Biological Sciences Subject Index Proc. NatL. Acad. Sci USA 81 (1984) 8103

Monodonta Mouse mammary tumor virus Mercury selection of allozymes in marine organisms: Prediction and Contacts between hormone receptor and DNA double helix within a verification in nature, 1258 glucocorticoid regulatory element of mouse mammary tumor Monokine virus, 3029 Specific absorption with monoclonal antibodies to muramyl dipeptide of Expression of an 86-kilodalton glycoprotein in an idiopathic mammary the pyrogenic and somnogenic activities of rabbit monokine, 5888 adenocarcinoma of a BALB/c mouse, 4159 Monooxygenase Properties of retrovirus-like particles produced by a human breast Structures of cysteine-coptaining peptides in isosafrole-inducible rat carcinoma cell line: Inmmunological relationship with mouse mammary hepatic microsomal cytochrome P-450d: with 3- tumor virus proteins, 4188 methylcholanthrene-induced cytochrome P-450c, 4298 Contacts between hormone receptor and DNA double helix within a Monte Carlo theory glucocorticoid regulatory element of mouse mammary tumor virus Interference of GTP hydrolysis in the mechanism of microtubule (Correction), 5892 assembly: An experimental study, 771 Mouse, RF/J Morphine Expression of differentiation and murine leukemia virus antigens on cells Inhibition of spontaneous and opiate-modified nociception by an of primary tumors and cell lines derived from chemically induced endogenous neuropeptide with Phe-Met-Arg-Phe-NH2-like lymphomas of RF/J mice, 7612 immunoreactivity, 5002 Movement Opioid receptor reserve in normal and morphine-tolerant guinea pig ileum Motor deficits in patients with large-fiber sensory neuropathy, 979 myenteric plexus, 7253 Moxalactam Morphogenesis Mechanism of the inhibition of the y-carboxylation of by N- See also Development and Differentiation methylthiotetrazole-containing , 2893 Cell adhesion and morphogenesis: The regulator hypothesis, 1460 mRNA cAMP pulses coordinate morphogenetic movement during fruiting body See also RNA formation of Dictyostelium minutum, 2122 Characterization of mouse myelin basic protein messenger with a Differential cellular distribution of cAMP-dependent protein kinase during myelin basic protein cDNA clone, 18 development of Dictyostelium discoideum, 2127 Nucleotide sequence and the encoded amino acids of human Increased adhesiveness of Down syndrome fetal fibroblasts in vitro, 2426 apolipoprotein A-I mRNA, 66 Epithelial mouse mammary cell line exhibiting normal morphogenesis in Bacterio-opsin mRNA in wild-type and bacterio-opsin-deficient vivo and functional differentiation in vitro, 3756 Halobacterium haloblum strains, 125 In vivo, cAMP stimulates growth and morphogenesis of mouse mammary Cell cycle regulation of human histone H1 mRNA, 434 ducts, 4950 Androgen induction of ornithine decarboxylase mRNA in mouse kidney Evolutionary conservation of key structures and binding functions of as studied by complementary DNA, 731 neural cell adhesion molecules, 6881 3' editing of mRNAs: Sequence requirements and involvement of a 60- Dissociation between testicular organogenesis and endocrine nucleotide RNA in maturation of histone mRNA precursors, 1057 cytodifferentiation of Sertoli cells, 7831 Two initiation sites detected in the small si species of reovirus mRNA by Morphology dipeptide synthesis in vitro, 1084 Snail shape and growth rates: Evidence for plastic shell allometry in Estradiol feedback effects on the a-subunit mRNA in the sheep pituitary Littorina littorea, 811 gland: Correlation with serum and pituitary luteinizing hormone concentrations, 1322 Mosbauer spectroscopy Messenger RNA for an antigen-specific binding molecule from an antigen- A consistent picture of protein dynamics, 7088 specific T-cell hybrid, 1524 MOsbauer spectrum Growth hormone-releasing factor regulates growth hormone mRNA in Theory of Mossbauer spectra of proteins fluctuating between primary cultures of rat pituitary cells, 1553 conformational substates, 5719 Selective reduction of c-myc mRNA in Daudi cells by human ,3 Motheaten interferon, 1747 Novel B-cell maturation factor from spontaneously autoimmune viable Isolation of a collagenase cDNA clone and measurement of changing motheaten mice, 7199 collagenase mRNA levels during induction of rabbit synovial MotiWt fibroblasts, 1981 erythro-9-(3-(2-Hydroxynonyl)]adenine is an effective inhibitor of cell Cloning and sequence analysis of cDNA from rat spleen thymosin motility and actin assembly, 6044 P4, 2295 Motor deficit Partial purification and characterization of the mRNA complementing a Motor deficits in patients with large-fiber sensory neuropathy, 979 temperature-sensitive S-phase cell cycle mutation, 2393 Mougeotia Temporal expression of late histone messenger RNA in the sea urchin Modulation of chloroplast movement in the green alga Mougeotia by the Lytechinus pictus, 2411 Ca2+ ionophore A23187 and by calmodulin antagonists, 6368 Isolation of hybridomas expressing a specific heavy chain variable region Mouse gene segment by using a screening technique that detects mRNA Lengths of chromosomal segments conserved since divergence of man sequences in whole cell lysates, 2470 and mouse, 814 Control of biologically active interleukin 2 messenger RNA formation in Mice homozygous for chromosomal deletions in the albino locus region induced human lymphocytes, 2601 lack specific polypeptides in two-dimensional gels, 2132 Characterization of leader RNA sequences on the virion and mRNAs of A large interspersed repeat found in mouse DNA contains a long open mouse hepatitis virus, a cytoplasmic RNA virus, 3626 reading frame that evolves as if it encodes a protein, 2308 Adenovirus tripartite leader sequence enhances translation of mRNAs Toward an analogue of alcoholism in mice: Scale factors in the late after infection, 3655 model, 3543 Nucleotide sequence of a growth-related mRNA encoding a member of Expression of an 86-kilodalton glycoprotein in an idiopathic mammary the prolactin-growth hormone family, 4255 adenocarcinoma of a BALB/c mouse, 4159 Individual products of the adenovirds 12S and 13S EIa mRNAs stimulate Neuronal influence on glial expression: Evidence from mutant viral Ella and EIII expression at the transcriptional level, 4381 mouse cerebella, 4414 A single rat gene generates three different mRNAs by Cellular homologs of the avian erythroblastosis virus erb-A and erb-B alternative splicing of a complex exon, 5140 genes are syntenic in mouse but asyntenic in man, 4874 Vasopressin gene is expressed at low levels in the hypothalamus of the Influence of early or late dietary restriction on life span and Brattleboro rat, 5296 immunological parameters in MRL/Mp-lpr/lpr mice, 5831 Translational regulation of the L11 ribosomal protein operon of Inhibition by restricted-calorie diet of lymphoproliferative disease and Escherichia coli: Analysis of the mRNA target site using renal damage in MRL/lpr mice, 6144 oligonucleotide-directed mutagenesis, 5389 Evidence that a major class of mouse endogenous long terminal repeats cDNA clone for the a-chain of human P3-hexosaminidase: Deficiency of (LTRs) resulted from recombination between exogenous retroviral a-chain mRNA in Ashkenazi Tay-Sachs fibroblasts, 5394 LTRs and similar LTR-like elements (LTR-IS), 6696 Role of mRNA translational efficiency in bovine growth hormone Expression of cellular oncogeqes during embryonic and fetal development expression in Escherichia coli, 5403 of the mouse, 7141 Locus unlinked to a-fetoprotein under the control of the murine raf and Direct transfection of viral and plasmid DNA into the liver or spleen of Rif genes, 5523 mice, 7529 Mapping of N6-methyladenosine residues in bovine prolactin Interferon induces pulmonary cysts in A2G mice, 7937 mRNA, 5667 Mouse embryo Differential expression of mRNAs for a- and /-tubulin during and some of A differentiation of the parasitic protozoan Leishmania mexicana, 5782 Amounts, synthesis, properties intracisternal particle- Synthesis in Escherichia coli of human adenovirus type 12 transforming related RNA in early mouse embryos, 488 proteins encoded by early region 1A 13S mRNA and 12S mRNA, 6300 Mouse-hamster hybrid Transcriptional induction of two genes in human cells by ( Assignment of the genes for the a and ,3 subunits of thyrotropin to interferon, 6733 different mouse chromosomes, 517 Creatine kinase protein sequence encoded by a cDNA made from Mouse hepatitis virus Torpedo californica electric- organ mRNA, 7007 Assembly in vitro of a spanning membrane protein of the endoplasmic Denervation of rat adrenal glands markedly increases preproenkephalin reticulum: The El glycoprotein of coronavirus mouse hepatitis virus mRNA, 7221 A59, 1421 Complete nucleotide sequence of Torpedo marmorata mRNA coding for Characterization of leader RNA sequences on the virion and mRNAs of the 43,000-dalton v2 protein: Muscle-specific creatine kinase, 7313 mouse hepatitis virus, a cytoplasmic RNA virus, 3626 Changing patterns of during sporulation in yeast, 7323 Mouse-human somatic cell hybrid Intron splicing: A conserved internal signal in introns of animal pre- On the mechanism of nucleolar dominance in mouse-human somatic cell mRNAs, 7417 hybrids, 484 Anti-mRNA: Specific inhibition of translation of single mRNA molecules, 7525 8104 Biological Sciences Subject Index Proc. NatL Acad. ScL USA 81 (1984)

Expression of the (-nerve growth factor gene correlates with the density Coordinate replication of members of the multigene family of core and H1 of sympathetic innervation in effector organs, 7951 human histone genes, 7723 Partial purification and functional expression of brain mRNAs coding for Clusters of HLA class HO(3 restriction fragments describe allelic neurotransmitter receptors and voltage-operated channels, 7994 series, 7870 mRNA activity profile Multinucleation Quantitative investigation of hepatic genomic response to hormonal and Multinucleation-induced improvement of the spreading of transformed pathophysiological stimuli by multivariate analysis of two-dimensional cells on the substratum, 3098 mRNA activity profiles, 974 Multiple endocrine neoplasia mRNA degradation 20 deletion in human multiple endocrine neoplasia types 2A Attenuation of the ilvB operon by amino acids reflecting substrates or and 2B: A double-blind study, 2525 products of the ilvB gene product, 76 Multiple sclerosis Extreme instability of myc mRNA in normal and transformed human Class II HLA-DC (3-chain DNA restriction fragments differentiate among cells, 7046 HLA-DR2 individuals in insulin-dependent diabetes and multiple mRNA expression sclerosis, 1774 Expression of specific mRNAs during adipose differentiation: Alteration of lipid-phase behavior in multiple sclerosis myelin revealed by Identification of an mRNA encoding a homologue of myelin P2 wide-angle x-ray diffraction, 1871 protein, 5468 Multiplication-stimulating activity a-Amnanitin-insensitive of mouse mjaJr-globin 5-flanking Placental lactogen administration reverses the effect of low-protein diet and structural gene sequences correlates with mRNA expression, 7782 on maternal and fetal serum somatomedin levels in the pregnant inRNA induction rat, 5853 Induction of mouse metallothionein-I mRNA by bacterial endotoxin is Multivariate analysis independent of metals and glucocorticoid hormones, 1053 Quantitative investigation of hepatic genomic response to hormonal and Differential induction of chalcone synthase mRNA activity at the onset of pathophysiological stimuli by multivariate analysis of two-dimensional phytoalexin accumulation in compatible and incompatible plant- mRNA activity profiles, 974 pathogen interactions, 3384 Multivesicular body Immune interferon activates multiple class II major histocompatibility Uptake of lectins by pulmonary alveolar type II cells: Subsequent complex genes and the associated invariant chain gene in human deposition into lamellar endothelial cells and dermal fibroblasts, 4917 bodies, 6383 Elicitor rapidly induces chalcone synthase mRNA in Phaseolus vulgaris Spec on with monoclonal antibodies to muramyl dipeptide of cells at the onset of the phytoalexin defense response, 5724 the pyrogenic and somnogenic activities of rabbit monokine, 5888 Photomorphogenesis in Physarum: Induction of tubulins and sporulation- Differential sleep-promoting effects of five sleep substances nocturnally specific proteins and of their mRNAs, 7117 infused in unrestrained rats, 6240 mRNA-interfering complementary RNA Murein A unique mechanism regulating gene expression: Translational inhibition Molecular model for elongation of the murein sacculus of Escherichia by a complementary RNA transcript (micRNA), 1966 coli, 1844 A unique mechanism regulating gene expression: Translational inhibition by a complementary RNA transcript (micRNA) Murine erythroleukemia cell (Correction), 4240 Inducer-mediated commitment of murine erythroleukemia cells to mRNA, low-abundance terminal cell division: The expression of commitment, 3394 Molecular cloning of cDNA for Avena phytochrome, 2332 Induction of a Ca2+,Mg2+-dependent activity during the mRNA, nuclear early stages of murine erythroleukemic cell differentiation, 7461 Rapid induction of a specific nuclear mRNA precursor by thyroid Murine leukemia virus hormone, 4687 A unique sequence related to the ecotropic murine leukemia virus is mRNA, polyclstronic associated with the Fv-4 resistance gene, 834 Analysis of Sendai virus mRNAs with cDNA clones of viral genes and Murine leukemia virus sequences are encoded in the murine major sequences of biologically important regions of the fusion protein, 7732 histocompatibility complex, 1804 mRNA precursor Proviruses are adjacent to c-myc in some murine leukemia virus-induced In vitro-synthesized adenovirus 2 messenger RNA precursors are lymphomas, 2097 accurately spliced by nuclear extracts, 4707 Construction of mutants of Moloney murine leukemia virus by mRNA processing suppressor-linker insertional mutagenesis: Positions of viable insertion Steps in processing of the mitochondrial cytochrome oxidase subunit I mutations, 4149 pre-mRNA affected by a nuclear mutation in yeast, 8 Isolation of immortal cell lines from the first stage of murine leukemia Cloning and characterization of cDNAs encoding human gastrin-releasing virus-induced leukemia, 5464 peptide, 5699 A mutant murine leukemia virus with a single missense codon in pol is mRNA purification defective in a function affecting integration, 6461 Isolation and identification of a cDNA clone coding for rat Introduction of a selectable gene into different animal tissue by a uroporphyrinogen decarboxylase, 3346 retrovirus recombinant vector, 7151 mRNA regulation Expression of differentiation and murine leukemia virus antigens on cells Single gene for the large subunit of ribulosebisphosphate carboxylase in of primary tumors and cell lines derived from chemically induced maize yields two differentially regulated mRNAs, 4060 lymphomas of RF/J mice, 7612 mRNA splicing Murine sarcoma virus Efficient coupled transcription and mRNA splicing in vitro using plasmids Autophosphorylation of v-Ha-ras p21 is modulated by amino acid residue derived from early region 3 of adenovirus 2 and a nondefective 12, 2674 adenovirus-simian virus 40 hybrid, 2679 Nucleotide sequence of avian carcinoma virus MH2: Two potential onc An unusual 5' splice sequence is efficiently utilized in vivo, 2733 genes, one related to avian virus MC29 and the other related to murine Altered mRNA splicing in monkey cells abortively infected with human sarcoma virus 3611, 3000 adenovirus may be responsible for inefficient synthesis of the virion Mus fiber polypeptide, 4023 A unique sequence related to the ecotropic murine leukemia virus is In vitro-synthesized adenovirus 2 messenger RNA precursors are associated with the Fv-4 resistance gene, 834 accurately spliced by nuclear extracts, 4707 A large interspersed repeat found in mouse DNA contains a long open Mu-1ac transducing phage reading frame that evolves as if it encodes a protein, 2308 In vivo formation of gene fusions encoding hybrid P-galactosidase Muscarihic agonist proteins in one step with a transposable Mu-lac transducing phage, 535 Decreased physiological sensitivity mediated by newly synthesized Mucolipidosis muscarinic acetylcholine receptors in embryonic chicken heart, 3582 Accumulation of coated vesicles bearing mannose 6-phosphate receptors Muscarinic receptor for lysosomal in the Golgi region of I-cell fibroblasts, 5135 Recognition of the muscarinic receptor by its endogenous Mucopolysaccharidoses neurotransmitter: Binding of [3HJacetylcholine and its modulation by Regional assignment of the structural gene for human a-L- transition metal ions and guanine nucleotides, 3650 iduronidase, 1169 Monoclonal antibodies to purified muscarinic receptor display agonist-like Mfillerian inhibitor activity, 4331 Dissociation between testicular organogenesis and endocrine Muscimol cytodifferentiation of Sertoli cells, 7831 Behavioral and neurochemical differentiation of specific projections in Multigene family the septal-hippocampal cholinergic pathway of the rat, 1880 Novel cluster of a-interferon gene sequences in a placental cosmid DNA Increase in the Bmax of y-aminobutyric acid-A recognition sites in brain library, 2435 regions of mice receiving diazepam, 2247 Evolution of multigene families under interchromosomal gene Muscle conversion, 3796 Calculation of the polarized fluorescence from a labeled muscle fiber, 145 Molecular cloning and characterization of a cDNA cloning for the Neuropeptide-induced contraction and relaxation of the mouse subunit of human alcohol dehydrogenase, 4055 anococcygeus muscle, 625 Isolation and characterization of a cDNA clone for human heavy Monoclonal antibodies detect a spectrin-like protein in normal and chain, 4751 dystrophic human skeletal muscle, 776 Clones from the human gene complex coding for salivary proline-rich Immunofluorescence analysis of the primordial myosin detectable in proteins, 5561 embryonic striated muscle, 797 Triplication of a four-gene set during evolution of the goat P-globin locus Denervated skeletal muscle displays discoordinate regulation for the produced three genes now expressed differentially during synthesis of several myofibrillar proteins, 1122 development, 6589 X-ray evidence for two structural states of the actomyosin cross-bridge in Human U1 RNA genes contain an unusually sensitive S1 muscle fibers, 2364 cleavage site within the conserved 3' flanking region, 7288 Biological Sciences Subject Index Proc. Nat. Acad. Sci. USA 81 (1984) 8105

In vitro transformation of mesenchymal cells derived from embryonic Role of a bridge in the immune function of major muscle into cartilage in response to extracellular matrix components of histocompatibility class I antigen as studied by in vitro bone, 3419 mutagenesis, 7544 31p NMR study of improvement in oxidative phosphorylation by vitamins Polycyclic aromatic hydrocarbon mutagenesis of human epidermal K3 and C in a patient with a defect in electron transport at complex III keratinocytes in culture, 7802 in skeletal muscle, 3529 Mutagenesis, oligonucleotide-directed Proteolysis and structure of skeletal muscle actin, 3680 Contact points between transcription machinery and the fibroin gene Titin is an extraordinarily long, flexible, and slender myofibrillar promoter deduced by functional tests of single-base substitution protein, 3685 mutants, 1394 Calcium-binding protein, , is reduced in mutant mammalian Translational regulation of the L11 ribosomal protein operon of muscle with abnormal contractile properties, 4814 Escherichia coli: Analysis of the mRNA target site using Monoclonal antibodies against the voltage-sensitive Na' channel from oligonucleotide-directed mutagenesis, 5389 mammalian skeletal muscle, 6227 Mugene, site-specific Muscle cell Specific amino acid substitutions in bacterioopsin: Replacement of a Electrical activity and cytosolic calcium regulate levels of tetrodotoxin- restriction fragment in the structural gene by synthetic DNA fragments sensitive sodium channels in cultured rat muscle cells, 262 containing altered codons, 2285 Goblin (ankyrin) in striated muscle: Identification of the potential Site-specific mutagenesis of the human fibroblast interferon gene, 5662 membrane receptor for erythroid spectrin in muscle cells, 3292 Mutagenicity Muscle degeneration Adaptive response in mammalian cells: Crossreactivity of different Cyclic GMP may serve as a second messenger in peptide-induced muscle pretreatments of cytotoxicity as contrasted to mutagenicity, 1062 degeneration in an insect, 6718 Mutation Muscle differentiation Drift and mutation with a finite number of allelic states, 530 Characterization and regulation in the expression of a gene coding for the Failure to demonstrate mutations affecting protein structure or function in intermediate filament protein desmin, 6909 children with congenital defects or born prematurely, 5499 Muscle fiber Demonstration of the production of frameshift and base-substitution Transformation by Rous sarcoma virus prevents acetylcholine receptor mutations by quasipalindromic DNA sequences, 5528 clustering on cultured chicken muscle fibers, 2265 Mutation, infectious Charge movement in skeletal muscle fibers paralyzed by the calcium- "Hopeful monsters," transposons, and Metazoan radiation, 5482 entry blocker D600, 2582 Mutation rate Muscle protein Autoradiographic assay of mutants resistant to diphtheria toxin in Application of the Dale-Eisinger analysis to proximity mapping in the mammalian cells in vitro, 6124 contractile system, 3723 Mutation, recurresnt Muscle relaxant Origin of the (3 -globin gene in Blacks: The contribution of recurrent Proteolytic activation of a bioactive cardiac peptide by in vitro trypsin mutation or gene conversion or both, 853 cleavage, 1230 Mutator gene Muscle, smooth mu-2: Mutator gene in Drosophila that potentiates the induction of Intramural mechanism of esophageal peristalsis: Roles of cholinergic and terminal deficiencies, 6090 noncholinergic nerves, 3595 Myasthenla ravis Pharmacomechanical coupling in smooth muscle may involve Acetyicholine receptor-specific suppressive T-cell factor from a phosphatidylinositol metabolism, 6899 retrovirally transformed T-cell line, 7569 Atrial natriuretic factor elicits an endothelium-independent relaxation and A noncholinergic site-directed monoclonal antibody can impair agonist- activates particulate guanylate cyclase in vascular smooth muscle, 7661 induced ion flux in Torpedo californica acetylcholine receptor, 7999 Muscle, ventricular Mycoplasma Characterization of genomic clones specifying rabbit a- and (-ventricular Streptococcal L-forms isolated from Drosophila paulistorum semispecies myosin heavy chains, 3044 cause sterility in male progeny, 282 Muscular dystrophy Myelin Monoclonal antibodies detect a spectrin-like protein in normal and Characterization of mouse myelin basic protein messenger RNAs with a dystrophic human skeletal muscle, 776 myelin basic protein cDNA clone, 18 X chromosome-linked muscular dystrophy (mdx) in the mouse, 1189 Schwann cell expression of a major myelin glycoprotein in the absence of Monensin-induced inhibition of cell spreading in normal and dystrophic myelin assembly, 1864 human fibroblasts, 4960 Alteration of lipid-phase behavior in multiple sclerosis myelin revealed by Abnormal collagen metabolism in cultured skin fibroblasts from patients wide-angle x-ray diffraction, 1871 with Duchqnne muscular dystrophy, 5130 Cultures of shiverer mutant cerebellum injected with normal Defective Ca"+ metabolism in Duchenne muscular dystrophy: Effects on oligodendrocytes make. both normal and shiverer myelin, 2558 cellular and viral growth, 7617 The structure of bovine brain myelin proteolipid and its organization in Mussel myelin, 2912 Isolation and identification of enkephalins in pedal ganglia of Mytilus Structure and molecular arrangement of proteolipid protein of central edulis (Mollusca), 955 nervous system myelin, 5012 Mutagen testing Myelin-associated glycoprotein A mutagen-testing assay based on heterogeneity in diameter and IgM in a human neuropathy related to paraproteinemia binds to a integrated optical density of mammalian cell colonies, 2112 carbohydrate determinant in the myelin-associated glycoprotein and to Mutagenesis a ganglioside, 1225 Construction and characterization of extrachromosomal probes for Myelin basic protein mutagenesis by carcinogens: Site-specific incorporation of o6- Characterization of mouse myelin basic protein messenger RNAs with a methylguanine into viral and plasmid genomes, 13 myelin basic protein cDNA clone, 18 Template requirements for the initiation of adenovirus DNA The structure of bovine brain myelin proteolipid and its organization in replication, 100 myelin, 2912 Ionizing radiation and tritium transmutation both cause formation of 5- Myelin P2 protein hydroxymethyl-2'-deoxyuridine in cellular DNA, 318 Expression of specific mRNAs during adipose differentiation: Fibroblasts from patients with hereditary cutaneous malignant melanoma Identification of an mRNA encoding a homologue of myelin P2 are abnormally sensitive to the mutagenic effect of simulated sunlight protein, 5468 and 4-nitroquinoline 1-oxide, 1179 Mutational specificity of depurination, 1494 Myelocytic leukemia Mutagenicity of quinones: Pathways of metabolic activation and Regression of myelocytic leukemia in rats after hypophysectomy, 598 detoxification, 1696 Myeloid cell Enzymatic techniques for the isolation of random single-base Monoclonal derivation of mouse myeloid and lymphoid lineages from substitutions in vitro at high frequency, 2030 totipotent hematopoietic stem cells experimentally engrafted in fetal In vitro mutagenesis and transcriptional analysis of a mouse ribosomal hosts, 7835 promoter element, 2137 Myoblast Analysis of the transforming potential of the human H-ras gene by Expression and regulation of chicken actin genes introduced into mouse random mutagenesis, 4008 myogenic and nonmyogenic cells, 2980 Construction of mutants of Moloney murine leukemia virus by Differentiation of myoblast cell lines and biological methylation: 3- suppressor-linker insertional mutagenesis: Positions of viable insertion Deazaadenosine stimulates formation of multinucleated myofibers, 3064 mutations, 4149 Growth hormone promotes the differentiation of myoblasts and Cholesterol epoxide is a direct-acting mutagen, 4198 preadipocytes generated by azacytidine treatment of 10T'/2 cells, 3429 Spontaneous and mutagen-induced deletions: Mechanistic studies in Myofiber Salmonella tester strain TA102, 4457 Differentiation of myoblast cell lines and biological methylation: 3- Enzymatic techniques for the isolation of random single-base Deazaadenosine stimulates formation of multinucleated myofibers, 3064 substitutions in vitro at high frequency (Correction), 4599 Myofibrill Construction and genetic characterization of temperature-sensitive mutant Titin is an extraordinarily long, flexible, and slender myofibrillar alleles of the yeast actin gene, 4889 protein, 3685 Autoradiographic assay of mutants resistant to diphtheria toxin in Myoglobin mammalian cells in vitro, 6124 Comparison of the magnetic properties of deoxy- and photodissociated In vivo mutagenesis by 06-methylguanine built into a unique site in a viral myoglobin, 2359 genome, 6271 Picosecond fluorescence decay of tryptophans in myoglobin, 4399 Molecular mechanisms of manganese mutagenesis, 7378 Antigen conformation determines processing requirements for T-cell Involvement of the activated form of RecA protein in SOS mutagenesis activation, 6831 and stable DNA replication in Escherichia coli, 7539 A consistent picture of protein dynamics, 7088 8106 Biological Sciences Subject Index Proc. NaMl. Acad. Sci. USA 81 (1984)

Myometrium Neissera Monoclonal antibodies to purified muscarinic receptor display agonist-like Pilus genes of Neisseria gonorrheae: Chromosomal organization and activity, 4331 DNA sequence, 6110 Myosin Nematode Immunofluorescence analysis of the primordial myosin detectable in A pheromone-induced developmental switch in Caenorhabditis elegans: embryonic striated muscle, 797 Temperature-sensitive mutants reveal a wild-type temperature- Isolation and partial renaturation of proteolytic fragments of the myosin dependent process, 819 head, 1003 Extrachromosomal copies of transposon Tcl in the nematode Denervated skeletal muscle displays discoordinate regulation for the Caenorhabditis elegans, 4018 synthesis of several myofibrillar proteins, 1122 A selection for myosin heavy chain mutants in the nematode X-ray evidence for two structural states of the actomyosin cross-bridge in Caenorhabditis elegans, 4470 muscle fibers, 2364 Neocarzinostatin Catalytic consequences of oligomeric organization: Kinetic evidence for Nitroaromatic radiation sensitizers substitute for oxygen in "tethered" acto-heavy meromyosin at low ATP concentrations, 5345 neocarzinostatin-induced DNA damage, 3312 Movement of scallop myosin on Nitella actin filaments: Regulation by Neocortex calcium, 6775 Subcortical projections from ectopic neocortical neurons, 964 Myosin heavy chain Neophobia Characterization of genomic clones specifying rabbit a- and (3-ventricular N{eophobia in the foraging-site selection of a neotropical migrant bird: An myosin heavy chains, 3044 experimental study, 3778 A selection for myosin heavy chain mutants in the nematode Neoplasia Caenorhabditis elegans, 4470 The neurula stage mouse embryo in control of neuroblastoma, 7608 Myosin heavy chain gene Neotoma Cardiac a- and (3-myosin heavy chain genes are organized in Seasonal aggression independent of seasonal testosterone in wood tandem, 2626 rats, 5255 Myosin light chain kinase Nerve Regulation of receptor capping in mouse lymphoma T cells by Ca2 - Denervated skeletal muscle displays discoordinate regulation for the activated myosin light chain kinase, 165 synthesis of several myofibrillar proteins, 1122 Myosin subfragment 1 Proteolysis and the domain organization of myosin subfragment 1, 736 Nerve, cholinergic Isolation and partial renaturation of proteolytic fragments of the myosin Intramural mechanism of esophageal peristalsis: Roles of cholinergic and head, 1003 noncholinergic nerves, 3595 On the mechanism of energy transduction in myosin subfragment 1, 2060 Nerve development Crystallization of myosin subfragment 1, 4378 Neutotrophic effects of hippocampal extracts on medial septal nucleus in Myristic acid vitro, 2567 Interactions of myristic acid with bovine : A '3C NMR Nerve growth factor study, 3718 Biochemical and anatomical effects of antibodies against nerve growth Covalently bound myristate in a lymphoma factor on developing rat sensory ganglia, 1580 tyrosine protein kinase, 7679 Nerve growth factor inhibits the synthesis of a single-stranded DNA Mytlus binding protein in pheochromocytoma cells (clone PC12), 2080 Isolation and identification of enkephalins in pedal ganglia of Mytilus C6 glioma cell-conditioned medium induces neurite outgrowth and edulis (Mollusca), 955 survival of rat chromaffin cells in vitro: Comparison with the effects of Myxococcus nerve growth factor, 2242 Two-dimensional S1 nuclease heteroduplex mapping: Detection of Insulin and insulin-like growth factor II permit nerve growth factor rearrangements in bacterial genomes, 2723 binding and the neurite formation response in cultured human Construction of Tn5 lac, a transposon that fuses lacZ expression to neuroblastoma cells, 2562 exogenous promoters, and its introduction into Myxococcus Structural gene for (-nerve growth factoi not defective in familial xanthus, 5816 dysautonomia, 4213 Developing dorsal root ganglion neurons require trophic support from NAD their central processes: Evidence for a role of retrogradely transported NAD of diphtheria toxin: Identification of a residue within nerve growth factor from the central nervous system to the the nicotinamide subsite by photochemical modification with periphery, 6245 NAD, 3307 Nerve growth factor gene NAD glycohydrolase Expression of the (-nerve growth factor gene correlates with the density Nonenzymic ADP-ribosylation of specific mitochondrial of sympathetic innervation in effector organs, 7951 polypeptides, 3929 Nerve growth factor receptor NADPH Characterization of nerve growth factor receptor in neural crest tumors Carbonyl oxygen exchange evidence of imine formation in the glutamate using monoclonal antibodies, 6681 dehydrogenase reaction and identification of the "occult role" of Nerve terminal NADPH, 2747 Micromolar-affinity benzodiazepine receptors regulate voltage-sensitive Catalase: A tetrameric enzyme with four tightly bound molecules of calcium channels in nerve terminal preparations, 3118 NADPH, 4343 Nervous system NaeRgenia Multiple opiate receptors in the guinea pig enteric nervous system: Chemically defined media for cultivation of Naegleria gruberi, 2406 Unmasking the copresence of receptor subtypes, 2252 Nalidixic acid Schwann cell proliferation and localized proteolysis: Expression of groEL and dnaK genes of Escherichia coli are induced by UV irradiation plasminogen-activator activity predominates in the proliferating cell and nalidixic acid in an htpR+-dependent fashion, 1499 populations, 7216 Nasopharyngeal carcinoma Nervus terminalis Detection of an Epstein-Barr virus-associated membrane antigen in The goldfish nervus terminalis: A luteinizing hormone-releasing hormone Epstein-Barr virus-transformed nonproducer cells by leukocyte and molluscan cardioexcitatory peptide immunoreactive olfactoretinal migration inhibition and blocking antibody, 4178 pathway, 940 Nasutdtermes Neural cell Soldier formation regulated by a primer pheromone from the soldier Identification of novel neural- and neural retina-specific antigens with a frontal gland in a higher termite, Nasutitermes lujae, 7665 monoclonal antibody, 2260 Natriuresis Neural cell adhesion molecule Proteolytic activation of a bioactive cardiac peptide by in vitro trypsin Alteration of neural cell adhesion molecule (N-CAM) expression after cleavage, 1230 neuronal cell transformation by Rous sarcoma virus, 969 Amino acid sequence of homologous rat atrial peptides: Natriuretic Fiber-fiber interaction and tectal cues influence the development of the activity of native and synthetic forms, 2640 chicken retinotectal projection, 1906 Natural killer cell Use of prokaryotic-derived probes to identify poly(sialic acid) in neonatal Pleiotropic activities of human interferons are mediated by multiple neuronal membranes, 1971 response pathways, 170 Neural crest A species of human a interferon that lacks the ability to boost human Perpendicular orientation and directional migration of amphibian neural natural killer activity, 4926 crest cells in dc electrical fields, 160 Liposomes as targets for granule cytolysin from cytotoxic large granular Neural development lymphocyte tumors, 5551 Two antigenically related neuronal cell adhesion molecules of different Inhibition of human natural killer cell activity by (14R,15S)-14,15- specificities mediate neuron-neuron and neuron-glia adhesion, 267 dihydroxy-5Z,8Z,1OE,12E-icosatetraenoic acid, 6914 Neural membrane Natural selection Movement of ions through fixed pores in the neural membrane, 5609 Mercury selection of allozymes in marine organisms: Prediction and Neuraminidase verification in nature, 1258 Use of prokaryotic-derived probes to identify poly(sialic acid) in neonatal Necrosin neuronal membranes, 1971 Necrosin: Purification and properties of a cytotoxin derived from a NH2-terminal hydrophobic region of influenza virus neuraminidase murine macrophage-like cell line, 7932 provides the signal function in translocation, 2327 Necturus Neurite Cell swelling increases a barium-inhibitable potassium conductance in the C6 glioma cell-conditioned medium induces neurite outgrowth and basolateral membrane survival of rat chromaffin cells in vitro: Comparison with the effects of of Necturus small intestine, 3591 nerve growth factor, 2242 Biological Sciences Subject Index Proc. NatL Acad. Sci. USA 81 (1984) 8107

Insulin and insulin-like growth factor II permit nerve growth factor Neuronal nuclear matrix binding and the neurite formation response in cultured human Ca2+/calmodulin-dependent protein kinases from the neuronal nuclear neuroblastoma cells, 2562 matrix and post-synaptic density are structurally related, 4311 Tunicamycin blocks neuritogenesis and glucosamine labeling of Neuronal plasticIty gangliosides in developing cerebral neuron cultures, 5638 Visualization of opiate receptor upregulation by light microscopy Neuroblastoma autoradiography, 3893 Enhanced expression of the human gene N-myc consequent to Neuropathy amplification of DNA may contribute to malignant progression of IgM in a human neuropathy related to paraproteinemia binds to a neuroblastoma, 4940 carbohydrate determinant in the myelin-associated glycoprotein and to The neurula stage mouse embryo in control of neuroblastoma, 7608 a ganglioside, 1225 Neuroblastoma cell In vitro evidence that covalent crosslinking of neurofilaments occurs in y- Insulin and insulin-like growth factor II permit nerve growth factor diketone neuropathy, 4979 binding and the neurite formation response in cultured human Prevention of some electrophysiologic and biochemical abnormalities with neuroblastoma cells, 2562 oxygen supplementation in experimental diabetic neuropathy, 6894 Neuroblastoma cells produce transforming growth factors during Neuropeptide exponential growth in a defined hormone-free medium, 4085 Neuropeptide-induced contraction and relaxation of the mouse Neurofibrillary tangle anococcygeus muscle, 625 Microtubule-associated protein 2: Monoclonal antibodies demonstrate the Evidence for parallel actions of a molluscan neuropeptide and serotonin selective incorporation of certain epitopes into Alzheimer in mediating arousal in Aplysia, 2934 neurofibrillary tangles, 7941 Identification of the second gonadotropin-releasing hormone in chicken Neurofibrillary tangle-bearing neuron hypothalamus: Evidence that gonadotropin secretion is probably Imaging of calcium and aluminum in neurofibrillary tangle-bearing controlled by two distinct gonadotropin-releasing hormones in avian neurons in parkinsonism-dementia of Guam, 1875 species, 3874 Imaging of calcium and aluminum in neurofibrillary tangle-bearing Cloning, characterization, and DNA sequence of a human cDNA neurons in parkinsonism-dementia of Guam (Correction), 4240 encoding neuropeptide tyrosine, 4577 Neurofilament A cDNA clone encoding neuropeptides isolated from Aplysia neuron occurs in y- 11, 4988 In vitro evidence that covalent crosslinking of neurofilaments Inhibition of spontaneous and opiate-modified nociception by an diketone neuropathy, 4979 endogenous neuropeptide with Phe-Met-Arg-Phe-NH2-like Neuromuscular junction immunoreactivity, 5002 Functional history of two motor neurons and the morphometry of their Neuropeptide-containing neurons of the cerebral cortex are also neuromuscular junctions in the gill of Aplysia: Evidence for differential GABAergic, 6526 aging, 4232 Isolation and sequencing of two cerebellum-specific peptides, 6866 Neuron The presence of pig brain of an endogenous equivalent of apamin, the bee Two antigenically related neuronal cell adhesion molecules of different venom peptide that specifically blocks Ca2+-dependent K+ specificities mediate neuron-neuron and neuron-glia adhesion, 267 channels, 7228 Subcortical projections from ectopic neocortical neurons, 964 Regional distribution of putative vasopressin receptors in rat brain and Neurotrophic factor for central neurons, 1248 pituitary by quantitative autoradiography, 7248 Axonal transport of a subclass of r proteins: Evidence for the regional Two endogenous neuropeptides modulate the gill and siphon withdrawal differentiation of microtubules in neurons, 1570 reflex in Aplysia by presynaptic facilitation involving cAMP-dependent Segregation of on- and off-center afferents in mink visual cortex, 1590 closure of a serotonin-sensitive potassium channel, 7956 Gastrin and cholecystokinin in pituitary neurons, 1902 Neuropeptide, invertebrate Histamine-containing neurons in the rat hypothalamus, 2572 Isolation and primary structure of two peptides with cardioacceleratory Substance P modulation of acetylcholine-induced currents in embryonic and hyperglycemic activity from the corpora cardiaca of Periplaneta chicken sympathetic and ciliary ganglion neurons, 2924 americana, 5575 Neurons with graded response have collective computational properties like those of two-state neurons, 3088 Neurophysin Synaptic stimulation alters protein phosphorylation in vivo in a single Method for quantitating the molecular content of a subcellular organelle: Aplysia neuron, 3233 Hormone and neurophysin content of newly formed and aged Numbers of specific types of neuron in layer IVab of cat striate neurosecretory granules, 180 cortex, 3898 Structure and comparison of the oxytocin and vasopressin genes from Alteration of the retinotectal map in Xenopus by antibodies to neural cell rat, 2006 adhesion molecules, 4222 Neurosecretory granule Functional history of two motor neurons and the morphometry of their Method for quantitating the molecular content of a subcellular organelle: neuromuscular junctions in the gill of Aplysia: Evidence for differential Hormone and neurophysin content of newly formed and aged aging, 4232 neurosecretory granules, 180 Tonically discharging putamen neurons exhibit set-dependent Neurospora responses, 4998 Molecular analysis of the Neurospora qa-l regulatory region indicates Tunicamycin blocks neuritogenesis and glucosamine labeling of that two interacting genes control qa gene expression, 1174 gangliosides in developing cerebral neuron cultures, 5638 The [pokyl mutant of Neurospora contains a 4-base-pair deletion at the 5' Herpes simplex virus latency in isolated human neurons, 6217 end of the mitochondrial small rRNA, 3791 Determination of synaptic phenotype: Insulin and cAMP independently Neurotensin initiate development of electrotonic coupling between cultured Xenopsin: The neurotensin-like octapeptide from Xenopus skin at the sympathetic neurons, 6235 carboxyl terminus of its precursor, 380 Developing dorsal root ganglion neurons require trophic support from Neurotoxin their central processes: Evidence for a role of retrogradely transported Reconstitution of neurotoxin-modalated ion transport by the voltage- nerve growth factor from the central nervous system to the regulated sodium channel isolated from the electroplax of periphery, 6245 Electrophorus electricus, 1239 The survival of brain transplants is enhanced by extracts from injured Neurotransmitter brain, 6250 Autoradiographic localization of II receptors in rat Monoclonal antibodies distinguish subtypes of retinal horizontal brain, 1575 cells, 6255 Recognition of the muscarinic receptor by its endogenous Neuropeptide-containing neurons of the cerebral cortex are also neurotransmitter: Binding of [3H]acetylcholine and its modulation by GABAergic, 6526 transition metal ions and guanine nucleotides, 3650 Enkephalin convertase localization by Is ATP a central synaptic mediator for certain primary afferent fibers [3H]guanidinoethylmercaptosuccinic acid autoradiography: Selective from mammalian skin?, 6890 association with enkephalin-containing neurons, 6543 Neurotransmitter receptor Polypeptide components and binding functions of neuron-glia cell Neurotransmitter receptors mediate cyclic GMP formation by adhesion molecules, 7989 involvement of arachidonic acid and lipoxygenase, 3905 Neuron L11 Partial purification and functional expression of brain mRNAs coding for A cDNA clone encoding neuropeptides isolated from Aplysia neuron neurotransmitter receptors and voltage-operated channels, 7994 Lii1, 4988 Neurotransmitter release Neuronal cell Free cytoplasmic Ca2+ and neurotransmitter release: Studies on PC12 Interactions of maitotoxin with voltage-sensitive calcium channels in cells and synaptosomes exposed to a-latrotoxin, 620 cultured neuronal cells, 4582 Neurotrophic factor Weak HLA and 832-microglobulin expression of neuronal cell lines can be Neurotrophic factor for central neurons, 1248 modulated by interferon, 6476 Partial characterization of the neurotrophic factor for maintenance of Neuronal and in the preganglionically Activity and the control of ganglion in the rat retina, 5589 denervated superior cervical ganglion of the cat in vivo, 6539 Neuronal development Neurovirulence Structural gene for ,(-nerve growth factor not defective in familial Comparison of the complete nucleotide sequences of the genomes of the dysautonomia, 4213 neurovirulent poliovirus P3/Leon/37 and its attenuated Sabin vaccine Neuronal growth cone derivative P3/Leon 12alb, 1539 Neuronal growth cones: Specific interactions mediated by filopodial Neurula insertion and induction of coated vesicles, 1849 The neurula stage mouse embryo in control of neuroblastoma, 7608 Neuronal membrane Neutral allele theory Use of prokaryotic-derived probes to identify poly(sialic acid) in neonatal The molecular clock may be an episodic clock, 8009 neuronal membranes, 1971 8108 Biological Sciences Subject Index Proc. Natl. Acad. Sci. USA 81 (1984)

Neutral mutation theory Dynamic filtering by two-dimensional 'H NMR with application to phage Guinea pig preproinsulin gene: An evolutionary compromise?, 5046 X repressor, 6019 Neutron capture Multiple-step relayed correlation spectroscopy: Sequential resonance Neutron-capture therapy of human cancer: In vivo results on tumor assignments in oligosaccharides, 6286 localization of boron-10-labeled antibodies to carcinoembryonic antigen Homonuclear 1H double-resonance difference spectroscopy of the rat in the GW-39 tumor model system, 560 brain in vivo, 6330 Neutron scattering In vivo metabolic effects of hyperglycemia in murine radiation-induced Structure of the cholesteryl ester core of human plasma low density fibrosarcoma: A 31P NMR investigation, 6496 lipoproteins: Selective deuteration and neutron small-angle Nociception scattering, 4389 Inhibition of spontaneous and opiate-modified nociception by an Neutrophil endogenous neuropeptide with Phe-Met-Arg-Phe-NH2-like Receptor-mediated activation of a A2 in rabbit neutrophil immunoreactivity, 5002 plasma membrane, 767 Nodulation 12S,20-Dihydroxyicosatetraenoic acid: A new icosanoid synthesized by Plasmid-linked nif and "nod" genes in fast-growing rhizobia that nodulate neutrophils from 12S-hydroxyicosatetraenoic acid produced by Glycine max, Psophocarpus tetragonolobus, and Vigna thrombin- or collagen-stimulated platelets, 903 unguiculata, 3093 Phagocytic cells metabolize 25-hydroxyvitamin D3 in vitro, 931 Noise elimnation Monitoring of cytosolic free Ca2 in C5a-itimulated neutrophils: Loss of Sharpening radiographs, 5237 receptor-modulated Ca2+ stores and Ca'+ uptake in granule-free Non-A, non-B hepatitis virus cytoplasts, 1416 Detection of non-A, non-B hepatitis antigen by immunocytochemical Stimulation of human granulocyte function by monoclonal antibody staining, 3195 WEM-G1, 1818 Nonheme iron Leukotriene B4 action on endothelium mediates augmented neutrophil/ Desulfovibrio vulgaris hydrogenase: A nonheme iron enzyme lacking endothelial adhesion, 2191 nickel that exhibits anomalous EPR and Mossbauer spectra, 3728 Oxidation of leukotrienes at the w end: Demonstration of a receptor for Nonhistone the 20-hydroxy derivative of leukotriene B4 on human neutrophils and Nuclear matrix DNA from chicken erythrocytes contains ,B-globin gene implications for the analysis of leukotriene receptors, 5729 sequences, 304 Leukotriene B4 mobilizes calcium without the breakdown of Nonsense mutation polyphosphoinositides and the production of phosphatidic acid in rabbit Heat shock response regulatory gene (htpR) of Escherichia coli is neutrophils, 5966 required for growth at high temperature but is dispensable at low Nickel temperature, 6803 Recognition of the muscarinic receptor by its endogenous Novikoff hepatoma cells neurotransmitter: Binding of [3H]acetylcholine and its modulation by Association of cytokeratin p39 with DNA in intact Novikoff hepatoma transition metal ions and guanine nucleotides, 3650 cells, 419 Ncotiana v2 protein Dimethyl sulfoxide can initiate cell divisions of arrested callus protoplasts Complete nucleotide sequence of Torpedo marmorata mRNA coding for by promoting cortical microtubule assembly, 5449 v2 creatine kinase, 7313 Nicotinamide the 43,000-dalton protein: Muscle-specific NAD binding site of diphtheria toxin: Identification of a residue within Nuclear antigen the nicotinamide subsite by photochemical modification with Identificat on of Epstein-Barr virus sequences that encode a nuclear NAD, 3307 antigen expressed in latently infected lymphocytes, 4373 Nuclear extract Nicotine In vitro-synthesized adenovirus 2 messenger RNA precursors are Adenosine strongly potentiates pressor responses to nicotine in rats, 5599 accurately spliced by nuclear extracts, 4707 Nicotinic receptor Nuclear factor I Intrinsic GABAergic system of adrenal chromaffin cells, 3218 DNA sequences required for the in vitro replication of adenovirus Nfedipine DNA, 3069 Interaction of calcium channel blockers with non-neuronal Isolation of human DNA sequences that bind to nuclear factor I, a host benzodiazepine binding sites, 1549 protein involved in adenovirus DNA replication, 4013 Nitella Nuclear magnetic resonance Movement of scallop myosin on Nitella actin filaments: Regulation by See also NMR calcium, 6775 Some plant leaves have orientation-dependent EPR and NMR Nitrendipine _ spectra, 748 Interaction of calcium channel blockers with non-neuronal 31P NMR study of improvement in oxidative phosphorylation by vitamins benzodiazepine binding sites, 1549 K3 and C in a patient with a defect in electron transport at complex III Nitrendipine block of cardiac calcium channels: High-affinity binding to in skeletal muscle, 3529 the inactivated state, 6388 In vivo nuclear magnetic resonance chemical shift imaging by selective Nitroaromatic radiation sensitizer irradiation, 6856 Nitroaromatic radiation sensitizers substitute for oxygen in Nuclear matrix neocarzinostatin-induced DNA damage, 3312 Tumor promoters induce a specific morphological signature in the nuclear Nitroceflulose filter matrix-intermediate filament scaffold of Madin-Darby canine kidney A quantitative dot-immunobinding assay for proteins using nitrocellulose (MDCK) cell colonies, 4409 membrane filters, 1684 Nuclear matrix DNA Nitrogen-15 Nuclear matrix DNA from chicken erythrocytes contains /3-globin gene "N electron nuclear double resonance of the primary donor cation radical sequences, 304 P", in reaction centers of Rhodopseudomonas sphaeroides: Additional Nuclear protein evidence for the dimer model, 7792 Avian myeloblastosis virus and E26 virus oncogene products are nuclear Nitrogen fixation proteins, 4265 H2-uptake activity of the MoFe protein component of Azotobacter Nuclear RNA vinelandii nitrogenase, 376 Organ-specific nuclear RNAs in tobacco, 2801 Construction of shuttle vectors capable of conjugative transfer from Rapid induction of a specific nuclear mRNA precursor by thyroid Escherichia coli to nitrogen-fixing filamentous cyanobacteria, 1561 hormone, 4687 Rhizobium free-living nitrogen fixation occurs in specialized nongrowing Nuclear tunneling cells, 1566 Tunneling in Chromatium chromatophores: Detection of a Hopfield Nitrogenase charge-transfer band, 135 H2-uptake activity of the MoFe protein component of Azotobacter Nuclease vinelandii nitrogenase, 376 Secondary structure specificity of the nuclease activity of the 1,10- Structural genes of dinitrogenase and dinitrogenase reductase are phenanthroline-copper complex, 3 transcribed from two separate promoters in the broad host range Nuclease hypersensitivity cowpea Rhizobium strain IRc78, 7358 Specific factor conferring nuclease hypersensitivity at the 5' end of the Nitrogenase promoter chicken adult P3-globin gene, 95 Expression of ,B-galactosidase controlled by a nitrogenase promoter in Nuclease SI stem nodules of Aeschynomene scabra, 5806 Two-dimensional S1 nuclease heteroduplex mapping: Detection of Nitrogenase reductase rearrangements in bacterial genomes, 2723 Structural genes of dinitrogenase and dinitrogenase reductase are Human U1 RNA genes contain an unusually sensitive transcribed from two separate promoters in the broad host range cleavage site within the conserved 3' flanking region, 7288 cowpea Rhizobium strain IRc78, 7358 aging 4-Nitroquinoline 1-oxide Modification of DNA by reducing sugars: A possible mechanism for Fibroblasts from pawients with hereditary cutaneous malignant melanoma nucleic acid aging and age-related dysfunction in gene expression, 105 are abnormally sensitive to the mutagenic effect of simulated sunlight Nucleic acid-binding molecule and 4-nitroquinoline 1-oxide, 1179 Nucleic acid-binding molecules with high affinity and base sequence N-Nitroso-N-methylurea specificity: Intercalating agents covalently linked to Regression of myelocytic leukemia in rats after hypophysectomy, 598 oligodeoxynucleotides, 3297 NMR Nucleic acid condensation See also Nuclear magnetic resonance Condensation of nucleic acids aromatic 7368 Detection of cerebral lactate in vivo during hypoxemia by 1H NMR at by intercalating cations, relatively low field strengths (1.9 T), 2517 Biological Sciences Subject Index Proc. Natl. Acadi Sci USA 81 (1984) 8109

Nucleic acid hybrIdIzation Molecular hybridization under conditions of high stringency permits Olroendrout1ultures ofshiverer mutant cerebellum injected with normal cloned DNA segments containing reiterated DNA sequences to be oligodendrocytes make both normal and shiverer myelin, 2558 assigned to specific chromosomal locations, 520 Oliomerif repeat Nucleic acid, modified of a unique enzyme from an alternative reading frame of the Chemically modified nucleic acids as immuinodetectable probes in preexisted, internally repetitious coding sequence, 2421 hybridization experiments, 3466 Segmental homology and internal repetitiousness identified in putative Nucleic add polymerase nucleic acid polymerase and human hepatitis B surface antigen of Segmental homology and internal repetitiousness identified in putative human hepatitis B virus, 3781 nucleic acid polymerase and human hepatitis B surface antigen of Oligonucleotide human hepatitis B virus, 3781 Nucleic acid-binding molecules with high affinity and base sequence Ncler dominance specificity: Intercalating agents covalently linked to On the mechanism of nucleolar dominance in mouse-human somatic cell oligodeoxynucleotides, 3297 hybrids, 484 Human genomic library screened with 17-base oligonucleotide probes Nucleolus yields a novel interferon gene, 6451 Localization of RNA polymerase I in interphase cells and mitotic Oligonadleotide purIfication chromosomes by light and electron microscopic Specific amino acid substitutions in bacterioopsin: Replacement of a immunocytochemistry, 1431 restriction fragment in the structural gene by synthetic DNA fragments Nucleoproteln containing altered codons, 2285 Isolation and visualization of active presynaptic filaments of recA protein Oligonucleotide, synthetic and single-stranded DNA, 7026 Role of a disulfide bridge in the immune function of major Nudeodde monophospbate histocompatibility class I antigen as studied by in vitro Mechanisms of glycosylation and sulfation in the Golgi apparatus: mutagenesis, 7544 Evidence for nucleotide sugar/nucleoside monophosphate and Ollosaccharide nucleotide sulfate/nucleoside monophosphate antiports in the Golgi Evaluation of critical groups required for the binding of heparin to apparatus membrane, 7051 , 1030 Nucleoside transport Monensin prevents terminal glycosylation of the N- and O-linked Intracellular lymphocyte activation and carrier-mediated transport of C8- oligosaccharides of the HLA-DR-associated invariant chain and inhibits substituted guanine ribonucleosides, 862 it dissociation from the a-P chain complex, 1287 5'-Nudeotidase Sulfation of lutropin oligosaccharides with a cell-free system, 5320 Identification of thymidine and deoxyribonucleotidase Linear organization of the liver cell adhesion molecule L-CAM, 5787 activities among normal isozymes of 5'-nucleotidase in human Multiple-step relayed correlation spectroscopy: Sequential resonance erythrocytes, 588 assignments in oligosaccharides, 6286 w oxidation Nudeotide Oxidation of leukotrienes at the w end: Demonstration of a receptor for '9mTc-labeled nucleotides as tumor-seeking radiodiagnostic agents, 918 on human and Nucleotide pool the 20-hydroxy derivative of leukotriene B4 neutrophils Imbalance oftotal cellular nucleotide pools and mechanism of the implications for the analysis of leukotriene receptors, 5729 colchicine-induced cell activation, 2401 On-center afferent Nucleotide sugar Segregation of on- and off-center afferents in mink visual cortex, 1590 Mechanisms of glycosylation and sulfation in the Golgi apparatus: Evidence for nucleotide sugar/nucleoside monophosphate and Isolon of transforming sequences of two human lung carcinomas: sulfate/nucleoside in the Golgi Structural and functional analysis of the activated c-K-ras nucleotide monophosphate antiports oncogenes, 71 apparatus membrane, 7051 Nucleotide sequence of the feline retroviral oncogene v-fms shows Nucleotide sulfate unexpected homology with oncogenes encoding tyrosine-specific Mechanisms of glycosylation and sulfation in the Golgi apparatus: protein kinases, 85 Evidence for nucleotide sugar/nucleoside monophosphate and A molecular approach to leukemogenesis: Mouse lymphomas contain an nucleotide sulfatelnucleoside monophosphate antiports in the Golgi activated c-ras oncogene, 202 apparatus membrane, 7051 Chromosome assignments of four mouse cellular homologs of sarcoma Nucleus and leukemia virus oncogenes, 525 Transfer of nuclei from a parasite to its host, 5420 The membrane glycoprotein encoded by the retroviral oncogene v-erb-B Amino terminus of the yeast GAL 4 gene product is sufficient for nuclear is structurally related to tyrosine-specific protein kinases, 704 localization, 5951 Products of a reciprocal chromosome translocation involving the c-myc Functions of purified ElA protein microinjected into mammalian gene in a murine plasmacytoma, 829 cells, 6988 Proviral deletions and oncogene base-substitutions in insertionally Specific DNA rearrangements in synchronously developing nuclei of mutagenized c-myc alleles may contribute to the progression of avian Tetrahymena, 7383 bursal tumors, 843 Isolation of the heterogeneous nuclear RNA-ribonucleoprotein complex Selective reduction of c-myc mRNA in Daudi cells by human f3 (hnRNP): A unique supramolecular assembly, 7471 interferon, 1747 Nude mouse Proviruses are adjacent to c-myc in some murine leukemia virus-induced Functional T cells in athymic nude mice, 886 lymphomas, 2097 nusB Hematopoietic cell transformation by a murine recombinant retrovirus nusB: A protein factor necessary for transcription antitermination in vitro containing the src gene of Rous sarcoma virus, 2374 by phage X N gene product, 6305 Autophosphorylation of v-Ha-ras p21 is modulated by amino acid residue Nutrition 12, 2674 Influence of early or late dietary restriction on life span and Nucleotide sequence of avian carcinoma virus MH2: Two potential onc immunological parameters in MRL/Mp-lpr/lpr mice, 5831 genes, one related to avian virus MC29 and the other related to murine Nylon oligomer sarcoma virus 3611, 3000 Birth of a unique enzyme from an alternative reading frame of the Transforming potential of a human protooncogene (c-fpslfes) locus, 3039 preexisted, internally repetitious coding sequence, 2421 Translocated c-myc oncogene of Burkitt lymphoma is transcribed in plasma cells and repressed in lymphoblastoid cells, 3170 Obesity Mechanism of activation of an N-ras oncogene of SW-1271 human lung Effects of food restriction on aging: Separation of food intake and carcinoma cells, 3670 adiposity, 1835 Analysis of the transforming potential of the human H-ras gene by Rapid recovery of body mass after surgical removal of adipose tissue in random mutagenesis, 4008 Avian myeloblastosis virus and E26 virus oncogene products are nuclear ground squirrels, 2270 proteins, 4265 Octopine Rous sarcoma virus variants that carry the cellular src gene instead of the Nucleotide sequence of the tms genes of the pTiA6NC octopine Ti viral src gene cannot transform chicken embryo fibroblasts, 4424 plasmid: Two gene products involved in plant tumorigenesis, 1728 A human c-erbA oncogene homologue is closely proximal to the Nucleotide sequence of the insertion sequence found in the T-DNA chromosome 17 breakpoint in acute promyelocytic leukemia, 4495 region of mutant Ti plasmid pTiA66 and distribution of its homologues Aberrant expression of an amplified c-myb oncogene in two cell lines in octopine Ti plasmid, 7495 from a colon carcinoma, 4534 Off-center afferent Nucleotide sequence 5' of the chicken c-myc coding region: Localization Segregation of on- and off-center afferents in mink visual cortex, 1590 of a noncoding exon that is absent from myc transcripts in most avian 1-Oleoyl-2-acetylglycerol leukosis virus-induced lymphomas, 4697 Diacylglycerol stimulates DNA synthesis and cell division in mouse 3T3 Molecular cloning and the total nucleotide sequence of the human c-Ha- cells: Role of Ca2+-sensitive phospholipid-dependent protein ras-1 gene activated in a melanoma from a Japanese patient, 4771 kinase, 5748 Cellular homologs of the avian erythroblastosis virus erb-A and erb-B Olfaction genes are syntenic in mouse but asyntenic in man, 4874 Ability to smell androstenone is genetically determined, 4899 Enhanced expression of the human gene N-myc consequent to Hippocampal denervation causes rapid forgetting of olfactory information amplification of DNA may contribute to malignant progression of in rats, 5885 neuroblastoma, 4940 Olactory bulb Monoclonal antibodies of predefined specificity detect activated ras gene Specific olfactory receptor populations projecting to identified glomeruli expression in human mammary and colon carcinomas, 5227 in the rat olfactory bulb, 5250 Expression of normal and transforming H-ras genes in Escherichia coli Olfatory cila and purification of their encoded p21 proteins, 5305 Membrane proteins unique to vertebrate olfactory cilia: Candidates for sensory receptor molecules, 1859 8110 Biological Sciences Subject Index Proc. NatL Acad. Sci USA 81 (1984)

A position 12-activated H-ras oncogene in all HS578T mammary Visualization of opiate receptor upregulation by light microscopy carcinosarcoma cells but not normal mammary cells of the same autoradiography, 3893 patient, 5384 Solubilization and characterization of Au, 8, and K opioid binding sites obl7 cells transformed by the middle-T-only gene of polyoma virus from guinea pig brain: Physical separation of K receptors, 4217 differentiate in vitro and in vivo into adipose cells, 5440 Psychotomimetic opiate receptors labeled and visualized with (+)_[3H]3- Translocation and rearrangement of c-myc into immunoglobulin a heavy (3-hydroxyphenyl)-N-(1-propyl)piperidine, 4983 chain locus in primary cells from acute lymphocytic leukemia, 5514 Opioid receptor reserve in normal and morphine-tolerant guinea pig ileum Specific regulation of c-myc oncogene expression in a murine B-cell myenteric plexus, 7253 lymphoma, 5546 Highly selective photoaffinity labeling of A± and 5 opioid receptors, 7718 Intrinsic GTPase activity distinguishes normal and oncogenic ras p21 Oploid peptide molecules, 5704 Compartmental distribution of striatal cell bodies expressing Biological activities of v-myc and rearranged c-myc oncogenes in rat [Met]enkephalin-like immunoreactivity, 7980 fibroblast cells in culture, 5758 Intact proenkephalin is the major enkephalin-containing peptide produced Human c-fos oncogene mapped within chromosomal region 14q21 in rat adrenal glands after denervation, 7985 q31, 5826 Opsonization Antibodies to two defined regions of the transforming protein pp6(YFc Suppression of phagocytic function and phospholipid metabolism in interact specifically with the epidermal growth factor receptor kinase macrophages by phosphatidylinositol liposomes, 2655 system, 5911 Optic nerve Activation of a translocated c-myc gene: Role of structural alterations in Two different Na,K-ATPases in the optic nerve: Cells of origin and the upstream region, 6798 axonal transport, 1234 A product of yeast RAS2 gene is a guanine nucleotide binding Substances originating from the optic nerve of neonatal rabbit induce protein, 6924 regeneration-associated response the injured optic nerve of adult Extreme instability of myc mRNA in normal and transformed human ip cells, 7046 rabbit, 7965 Overexpression of the c-src protein does not induce transformation of Optical density NIH 3T3 cells, 7071 A mutagen-testing assay based on heterogeneity in diameter and src- andfps-containing avian sarcoma viruses transform chicken erythroid integrated optical density of mammalian cell colonies, 2112 cells, 7122 Oran0 e Expression of cellular oncogenes during embryonic and fetal development Method for quantitating the molecular content of a subcellular organelle: of the mouse, 7141 Hormone and neurophysin content of newly formed and aged Nucleotide sequence 5' of the chicken c-myc coding region: Localization neurosecretory granules, 180 of a noncoding exon that is absent from myc transcripts in most avian Extensive and widespread homologies between mitochondrial DNA and leukosis virus-induced lymphomas (Correction), 7258 chloroplast DNA in plants, 1946 Characterization of epidermal growth factor receptor gene expression in Organelle biogenesis malignant and normal human cell lines, 7308 Synthesis of a major integral membrane protein polypeptide of rat liver The protein encoded by the human proto-oncogene c-myc, 7742 peroxisomes on free polysomes, 7127 Mouse c-mos oncogene activation is prevented by upstream Qrlentajs sequences, 7817 Molecular abnormality of an inactive aldehyde dehydrogenase variant Oncogenesis commonly found in Orientals, 258 Crown gall oncogenesis: Evidence that a T-DNA gene from the Origin of life Agrobacrerium Ti plasmid pTiA6 encodes an enzyme that catalyzes A model for the origin of biological catalysis, 1751 synthesis of indoleacetic acid, 5071 A model for the origin of biological catalysis (Correction), 4599 Oocyte, Origin of replication Artifacts caused by cell microinjection, 1426 Prbtein HU in the enzymatic replication of the chromosomal origin of Birth of rhesus monkey infant after in vitro fertilization and nonsurgical Escherichia coli, 424 embryo transfer, 2218 RNase H confers specificity in the dnaA-dependent initiation of In vivo effects of microinjected alkaline and its low replication at the unique origin of the Escherichia coli chromosome in molecular weight substrates on the first meiotic cell division in vivo and in vitro, 1040 Xenopus laevis oocytes, 5150 Mouse primase initiation sites in the origin region of simian virus 40, 2342 A Ca2+-activated channel from Xenopus laevis oocyte membranes The simian virus 40 minimal origin and the 72-base-pair repeat are reconstituted into planar bilayers, 5155 required simultaneously for efficient induction of late gene expression Injection of partially purified estrogen receptor protein from Xenopus with large tumor antigen, 6335 liver nuclei into oocytes activates the silent vitellogenin locus, 5777 Simian virus 40 DNA replication in vitro, 6973 Oogenesis Multiple initiation sites of DNA replication flanking the origin region of Specific protein modifications are altered in a temperature-sensitive Xdv genome, 7402 Drosophila developmental mutant, 6422 Ornithine carbanwyltransferase Open reading frame Molecular cloning and nucleotide sequence of cDNA for rat ornithine A large interspersed repeat found in mouse DNA contains a long open carbamoyltransferase precursor, 7412 reading frame that evolves as if it encodes a protein, 2308 Ornithine decarboxylase Birth of a unique enzyme from an alternative reading frame of the Molecular cloning and expression of the mouse ornithine decarboxylase preexisted, internally repetitious coding Sequence, 2421 gene, 540 Predicted secondary structure similarity in the absence of primary amino Androgen induction of ornithine decarboxylase mRNA in mouse kidney acid sequence homology: Hepatitis B virus open reading frames, 2902 as studied by complementary DNA, 731 homology and internal repetitiousness identified in putative Isolation of cloned cDNA encoding mammalian ornithine Seg!Tentalnucleic acid polymerase and human hepatitis B surface antigen of decarboxylase, 3645 human hepatitis B virus, 3781 Ornithine transcarbamoylase Operator Protein differentiation: A comparison of aspartate transcarbamoylase and Two-dimensional 1H NMR study of the A operator site OLI: A sequential ornithine transcarbamoylase from Escherichia coli K-12, 4864 assignment strategy and its application, 130 Orphon Use of the Escherichia coli lac repressor and operator to control gene Variant antigen genes of Trypanosoma brucei: Genomic alteration of a expression in Bacillus subtilis, 439 spliced leader orphon and retention of expression-linked copies during Cocrystals of the DNA-binding domain of phage 434 repressor and a differentiation, 684 synthetic phage 434 operator, 1307 Variant antigen genes of Trypanosoma brucei: Genomic alteration of a Possible ideal lac operator: Escherichia coli lac operator-like sequences splicbd leader orphon and retention of expression-linked copies during from eukaryotic genomes lack the central G-C pair, 1624 differentiation (Correction), 2944 DNA sequences of the repressor gene and operator region of Oscillation bacteriophage P2, 3988 Transitions between oscillatory modes in a glycolytic model system, 4394 An operator at -280 base pairs that is required for repression of araBAD operon promoter: Addition of DNA helical turns between the operator Oscillator and promoter cyclically hinders repression, 5017 Biological system interactions, 2938 Mercuric ion-resistance operons of plasmid R100 and transposon Tn501: Osmoregulation The beginning of the operon including the regulatory region and the A unique mechanism regulating gene expression: Translational inhibition first two structural genes, 5975 by a complementary RNA transcript (micRNA), 1966 Demonstration of two operator elements in gal: In vitro repressor binding A unique mechanism regulating gene expression: Translational inhibition studies, 6100 by a complementary RNA transcript (micRNA) (Correction), 4240 Osteoblast Opiate Macrophage-derived growth factor for osteoblast-like cells and a opiates and wertain antipsychotic drugs mutually inhibit (+)-[3H]SKF 4558 10,047 and [ Hlhaloperidol binding in guinea pig brain membranes, 5618 chonlrocytes, Opiate receptor Osteoclast Inhibition of opiate receptor-mediated signal transmission by rabies virus Recombinant human t-interferon induces human monocyte polykaryon in persistently infected NG-108-15 mouse neuroblastoma-rat glioma formation, 4554 hybrid cells, 950 Osteodast-activating factor Multiple opiate receptors in the guinea pig enteric nervous system: Thymus-derived lymphocytes and their interactions with macrophages are Unmasking the copresence of receptor subtypes, 2252 required for the production of osteoclast-activating factor in the Multiple opioid receptors in endotoxic shock: Evidence for a involvement mouse, 2181 and A-S interactions in vivo, 2898 Osteogenesis ' ,8-Endorphin: Characterization of binding sites specific for the human Purification of bovine bone morphogenetic protein by hydroxyapatite hormone in human glioblastoma SF126 cells, 2921 chromatography, 371 f-Endorphin-induced analgesia is inhibited by synthetic analogs of,& endorphin, 3074 Biological Sciences Subject Index Proc. NatL. Acad. Sci. USA 81 (1984) 8111

Osteogenesis imperfecta p30 protein , bone , and phosphophoryn defects in a form of Detection and immunochemical characterization of a primate type C bovine osteogenesis imperfecta, 2213 retrovirus-related p30 protein in normal human placentas, 6501 Nuclease S1 mapping of a homozygous mutation in the carboxyl- p1OO protein propeptide-coding region of the proa2(I) collagen gene in a patient with Identification of a labile protein involved in the GI-to-S transition in osteogenesis imperfecta, 4524 Saccharomyces cerevisiae, 120 Osteonectin P element Osteonectin, bone proteoglycan, and phosphophoryn defects in a form of Inducible transcription and puffing in Drosophila melanogaster bovine osteogenesis imperfecta, 2213 transformed with hsp7O-phage X hybrid heat shock genes, 5509 Monoclonal antibodies to native noncollagenous bone-specific Sequences homologous to P elements occur in Drosophila proteins, 2868 paulistorum, 6794 Ouabain Interspecific DNA transformation in Drosophila, 7515 Molecular cloning of the mouse ouabain-resistance gene, 1489 Palaemon Phorbol 12-myristate 13-acetate, ionomycin or ouabain, and raised Mercury selection of allozymes in marine organisms: Prediction and extracellular magnesium induce proliferation of chicken heart verification in nature, 1258 mesenchymal cells, 6418 Paleoecology Outcrossing Guatemalan forest synthesis after Pleistocene aridity, 4856 Estimation of mating systeit parameters when outcrossing events are Paleontology correlated, 5258 Periodicity of in the geologic past, 801 Ovarian carcinoma Palindrome Cell surface antigens of human ovarian and endometrial carcinoma Structural intermediates of deletion mutagenesis: A role for palindromic defined by mouse monoclonal antibodies, 568 DNA, 512 Oviduct Evidence for the existence of stable curvature of DNA in solution, 4632 Molecular cloning of a cDNA for the chicken progesterone receptor B Palmitate antigen, 6358 The presence of cysteine in the cytoplasmic domain of the vesicular Owl monkey stomatitis virus glycoprotein is required for palmitate addition, 2050 Transformation of owl monkey T cells in vitro with Herpesvirus Palmitoylhomocysteine saimiri, 4563 pH-sensitive liposomes: Acid-induced liposome fusion, 1715 Oxidase Palynology The possibility that the spectrum of intermediate two, seen in the course Guatemalan forest synthesis after Pleistocene aridity, 4856 of reaction of flavoenzyme phenol hydroxylases, may be attributable to Pancreas iminol isomers of a flavin-derived 6-arylamino-5-oxo(3H,SH)uracil, 332 Cytosolic calcium regulates epidermal growth factor endocytosis in rat Oxidation pancreas and cultured fibroblasts, 461 Spectroscopic studies of ferricyanide bxidation of Azotobacter vinelandii Boinbesin stimulates insulin secretion by a pancreatic islet cell line, 1822 ferredoxin I, 1931 Leukotrienes stimulate insulin release from the rat pancreas, 2199 Lignoceric acid is oxidized in the peroxisome: Implications for the Extrapancreatic insulin gene expression in the fetal rat, 3635 Zellweger cerebro-hepato-renal syndrome and Conversion of proglucagon in pancreatic alpha cells: The major adrenoleukodystrophy, 4203 endproducts are glucagon and a single peptide, the major proglucagon Chemical reduction of oxidized human lymphocytes inhibits interleukin 2 fragment, that contains two glucagon-like sequences, 5007 production but not induction of interleukin 2 responsiveness, 5209 Pancreatic cancer DNA damage related to increased hydrogen peroxide generation by Detection of a pancreatic cancer-associated antigen (DU-PAN-2 antigen) hypolipidemic drug-induced liver peroxisomes, 7827 in serum and ascites of patients with adenocarcinoma, 5242 Oxidative damage Pancreatic carcinoma Hydroxymethyluracil DNA glycosylase in mammalian cells, 4003 Inhibition of growth of pancreatic carcinomas in animal models by Oxidative inactivation analogs of hypothalamic hormones, t48 Oxidative inactivation of glutamine synthetase subunits, 2011 Pancreatic icosapeptide Human pancreatic icosapeptide: Isolation, sequence, and of improvement in oxidative phosphorylation by vitamins immunocytochemical localization of the COOH-terminal fragment of K3 and d in a patient with a defect in electron transport at complex III the pancreatic polypeptide precursor, 708 in skeletal muscle, 3529 Pangreatic polypeptide Amino acid sequence of bovine heart coupling factor 6, 6603 Human pancreatic icosapeptide: Isolation, sequence, and Oxygen immunocytochemical localization of the COOH-terminal fragment of Active oxygen acts as a promoter of transformation in mouse embryo the panpieatic polypeptide precursor, 708 C3H/1OT1/2/C18 fibroblasts, 2085 Papillonavirus Nitroaromatic radiation sensitizers substitute for oxygen in Identification of a second transforming region in bovine papillomavirus neocarzinostatin-induced DNA damage, 3312 Dr4A, 7880 Thymine glycol and thymidine glycol in human and rat urine: A possible Paraffin bil assay for oxidative DNA damage, 5633 1426 Oxygen regulation of anaerobic and aerobic genes mediated by a common Artifacts caused by cell microinjection, factor in yeast, 6129 Parallel evolution Prevention of some electrophysiologic and abnormalities with DNA sequence transfer between two high-cysteine chorion gene families oxygen supplementation in experimental biophemicaldiabetic neuropathy, 6894 in the $ilkmoth Bombyx mori, 4452 Oxygen consumption Parallel fiber Biochemical and physiological correlates of deer mouse a-chain Adenosine selectively blocks parallel-fiber-mediated synaptic potentials in hemoglobin polymorphisms, 5484 rat cerebellar cortex, 6531 Oxygen-tvolving enzyme Paramyxovirus Charge accumulation and photochemistry in leaves studied by Fusion protein of the paramyxovirus simian virtis 5: Nucleotice sequence thermoluminescence and delayed light emission, 1107 of mRNA predicts a highly hydrophobic glycoprotein, 6706 Oxygen exchange Nucleotide sequence of the gene encoding the fusion (F) glycoprotein of Carbonyl oxygen exchange evidence of imine formation in the glutamate human respiratory syncytial virus, 7683 dehydrogenase reaction and identification of the "occult role" of Paraproteinenmia NADPH, 2747 IgM in a human qeuropathy related to paraproteipemia binds to a Oxygen unloading carbohydrate determinant in the myelin-associated glycoprotein and to Enhanced oxygen unloading by an interdimerically crosslinked a ganglioside, 1225 hemoglobin in an isolated perfused rabbit heart, 2941 Parasite Oxygenase Transfer of nuclei from a parasite to its host, 5420 Lignin-degrading enzyme from Phanerochaete chrysosporium: Parasite detection Purification, characterization, and catalytic properties of a unique Minichromosomal repetitive DNA in Trypanosoma cruzi: Its ute in a H202-requiring oxygenase, 2280 high-sensitivity parasite detection assay, 3356 Oxyhemoglobin Parathyroid cell Magnetic susceptibility of oxy- and carbonmonoxyhemoglobins, 5417 Relationship between parathyroid hormone secretion and cytosolic Oxytoci calcium concentration in dispersec bovine parathyroid cells, 3113 Method for quantitating the molecular content of a subcellular organelle: Parathyroid hormone Hormone and neurophysin content of newly formed and aged Relationship between parathyroid hormone secretion and cytosolic neurosecretory granules, 18p calcium concentration in dispersed bovine parathyroid cells, 3113 Structure and comparison of the oxytocin and vasopressin genes from Secretion of human parathyroid hormone from rat pituitary cells infected rat, 2006 with a recombinarlt retrovirus encodinig preproparathyroid Oxytricha hormone, 5340 Elaboration of telomeres in yeast: Recognition and modification of Paraventricular nucleus from macronuclear DNA, 1475 Corticotropin-releasing factor-immunoreactive neurons of the termini Oxytricha paraventricular nucleus become vasopressin positive after p21 protein adrenalectomy, 1854 Expression of normal and transforming H-ras genes in Escherichia coli Parkinson disease and purification of their encoded p21 proteins, 5305 Dopamine receptor turnover rates in rat striatum are age-dependent, 3910 Intrinsic GTPase activity distinguishes normal and oncogenic ras p21 Parkinsonism molecules, 5704 Parkinsonism-inducing neurotoxin, N-methyl-4-phenyl-1,2,3,6- Guanosine nucleotide binding by highly purified Ha-ras-encoded p21 tetrahydropyridine: Characterization and localization of receptor protein produced in Escherichia col, 6953 binding sites in rat and human brain, 4591 8112 Biological Sciences Subject Index Proc. NatL Acad ScL USA 81 (1984)

Parkinsonism-dementia Portage of various compounds into by attachment to glycine Imaging of calcium and aluminum in neurofibrillary tangle-bearing residues in peptides, 4573 neurons in parkinsonism-dementia of Guam, 1875 Peremyscus Imaging of calcium and aluminum in neurofibrillary tangle-bearing Biochemical and physiological correlates of deer mouse a-chain neurons in parkinsonism-dementia of Guam (Correction), 4240 hemoglobin polymorphisms, 5484 Parvalbumin Peroxidation Calcium-binding protein, parvalbumin, is reduced in mutant mammalian Lipid peroxidation forms ethylene from 1-aminocyclopropane-1- muscle with abnormal contractile properties, 4814 carboxylic acid and may operate in leaf senescence, 1724 Calcium-binding proteins in human carcinoma cell lines, 6632 Peroxisome Parvocellular neurosecretory neuron Lignoceric acid is oxidized in the peroxisome: Implications for the Co-expression of corticotropin-releasing factor and vasopressin Zellweger cerebro-hepato-renal syndrome and immunoreactivity in parvocellular neurosecretory neurons of the adrenoleukodystrophy, 4203 adrenalectomized rat, 1883 Maturation of catalase precursor proceeds to a different extent in Patch-clamp glyoxysomes and leaf peroxisomes of pumpkin cotyledons, 4809 Acetylcholine receptor (from Electrophorus electricus): A comparison of Synthesis of a major integral membrane protein polypeptide of rat liver single-channel current recordings and chemical kinetic peroxisomes on free polysomes, 7127 measurements, 5281 DNA damage related to increased hydrogen peroxide generation by Pathophysiological stimulus hypolipidemic drug-induced liver peroxisomes, 7827 Quantitative investigation of hepatic genomic response to hormonal and Pertussis toxin pathophysiological stimuli by multivariate analysis of two-dimensional Pertussis toxin differentiates between two mechanisms of attenuation of mRNA activity profiles, 974 cyclic AMP accumulation by muscarinic cholinergic receptors, 5680 Pausing Pest attack Pausing and premature termination of human RNA polymerase II during Wound signals in plants: A systemic plant wound signal alters plasma transcription of adenovirus in vivo and in vitro, 5931 membrane integrity, 3737 Pea Petroselinum Purification and properties of a pea chloroplast DNA polymerase, 2354 Induction of ammonia- and 4-coumarate:CoA Structure and expression of a pea nuclear gene encoding a chlorophyll mRNAs in cultured plant cells by UV light or fungal elicitor, 1102 a/b-binding polypeptide, 2960 pH Regulation of pea seed pyrophosphate-dependent phosphofructokinase: See also Acid and Hydrogen ion concentration Evidence for interconversion of two molecular forms as a glycolytic pH-sensitive liposomes: Acid-induced liposome fusion, 1715 regulatory mechanism, 5051 Mechanism of cytoplasmic pH regulation in hypoxic maize root tips and Cytoplasmic acidosis as a determinant of flooding intolerance in its role in survival under hypoxia, 3379 plants, 6029 Cytoplasmic acidosis as a determinant of flooding intolerance in Pemphigus plants, 6029 Human autoantibodies against desmosomes: Possible causative factors in In vivo metabolic effects of hyperglycemia in murine radiation-induced pemphigus, 2781 fibrosarcoma: A 31P NMR investigation, 64% Penicillin A correlation between proton pumping and the bacteriorhodopsin P-Lactamase-catalyzed hydrolysis of acyclic depsipeptides and acyl photocycle, 7079 transfer to specific amino acid acceptors, 1302 On the protein (tyrosine)-chromophore (protonated Schiff base) coupling Pepsin in bacteriorhodopsin, 7083 Pepsin digestibility of proteins in sorghum and other major cereals, 1 Na+-H+ exchange in gastric glands as measured with a cytoplasmic- Amino acid sequence of porcine spleen cathepsin D, 3703 trapped, fluorescent pH indicator, 7436 Human renin gene: Structure and sequence analysis, 5026 Effects of pH on the structure and function of carboxypeptidase A: Peptidase Crystallographic studies, 7767 Portage of various compounds into bacteria by attachment to glycine Phage residues in peptides, 4573 See Bacteriophage Peptide biosynthesis Paocyte Cloning and sequence adalysis of cDNA from rat spleen thymosin The mononuclear phagocyte system of the mouse defined by 34, 2295 immunohistochemical localization of antigen F4/80: Macrophages of Peptide bond endocrine organs, 4174 Detection of cis and trans X-Pro peptide bonds in proteins by 13C NMR: Phagocytosis Application to collagen, 4800 Phagocytic cells metabolize 25-hydroxyvitamin D3 in vitro, 931 Peptide conformation Suppression of phagocytic function and phospholipid metabolism in On the use of sequence homologies to predict protein structure: Identical macrophages by phosphatidylinositol liposomes, 2655 pentapeptides can have completely different conformations, 1075 Immunosuppression in vitro by a metabolite of a human pathogenic Peptide hormone fungus, 3835 Role of membrane lipids in peptide hormone function: Binding of The increase in intracellular free calcium associated with IgG'y2b/'yl Fc enkephalins to micelles, 61 receptor-ligand interactions: Role in phagocytosis, 5430 Expression of pro-opiomelanocortin-like gene in the testis and The increase in intracellular free calcium associated with IgGy2b/-yl Fc epididymis, 5672 receptor-ligand interactions: Role in phagocytosis (Correction), 7258 Peptide release Phalloidin A ligand-specific action of chelated copper on hypothalamic neurons: Identity of hepatic membrane transport systems for bile salts, phalloidin, Stimulation of the release of luteinizing hormone-releasing hormone and antamanide by photoaffinity labeling, 5232 from median eminence explants, 7656 Phanerochaete Peptide synthesis Lignin-degrading enzyme from Phanerochaete chrysosporium: Use of peptide synthesis to probe viral antigens for epitopes to a Purification, characterization, and catalytic properties of a unique resolution of a single amino acid, 3998 H202-requiring oxygenase, 2280 Peptide, synthetic Phanerozoic Anti-hypervariable region antibody induced by a defined peptide: An "Hopeful monsters," transposons, and Metazoan radiation, 5482 approach for studying the structural correlates of idiotypes, 1784 Pharmacomechanical coupling Peptide transport Pharmacomechanical coupling in smooth muscle may involve Portage of various compounds into bacteria by attachment to glycine phosphatidylinositol metabolism, 6899 in 4573 Phase change residues peptides, Phase changes at the end of a microtubule with a GTP cap, 5772 Peptidyl site Phase transition Identification of a site on 23S ribosomal RNA located at the peptidyl The effects of water-soluble solutes on the phase transitions of center, 3607 phospholipids, 1398 Periodicity Lamellar-to-hexogonall, phase transitions in the plasma membrane of The hydrophobic moment detects periodicity in protein isolated protoplasts after freeze-induced dehydration, 6373 hydrophobicity, 140 Phase variation Periodicity of extinctions in the geologic past, 801 A genetic switch in vitro: DNA inversion by Gin protein of phage Peripheral binding site Mu, 2689 Benzodiazepines that bind at peripheral sites inhibit cell proliferation, 753 Two-dimensional S1 nuclease heteroduplex mapping: Detection of Periplaneta rearrangements in bacterial genomes, 2723 Isolation and primary structure of two peptides with cardioacceleratory Pilus genes of Neisseria gonorrheae: Chromosomal organization and and hyperglycemic activity from the corpora cardiaca of Periplaneta DNA sequence, 6110 amnericana, 5575 Phaseolus Periplasm Elicitor rapidly induces chalcone synthase mRNA in Phaseolus vulgaris ATP-binding sites in the membrane components of the histidine cells at the onset of the phytoalexin defense respohse, 5724 permease, a periplasmic transport system, 7333 Phe-Met-Arg-Phe-NH2 Protein export in Escherichia coli requires a soluble activity, 7737 Inhibition of spontaneous and opiate-modified nociception by an Peristalsis endogenous neuropeptide with Phe-Met-Arg-Phe-NH2-like Intramural mechanism of esophageal peristalsis: Roles of cholinergic and immunoreactivity, 5002 noncholinergic nerves, 3595 1,10-Phenanthroline Permease Secondary structure specificity of the nuclease activity of the 1,10- Purified reconstituted lac carrier protein from Escherichia coli is fully phenanthroline-copper complex, 3 functional, 1629 Biological Sciences Subject Index Proc. Natl. Acad. Sci. USA 81 (1984) 8113

Phenobarbital Purification and properties of branched-chain a-keto acid dehydrogenase Distinct organization of methylcholanthrene- and phenobarbital-inducible phosphatase, 4335 cytochrome P-450 genes in the rat, 5066 Phosphate Phenol hydroxylase Regulated expression of a human interferon gene in yeast: Control by The possibility that the spectrum of intermediate two, seen in the course phosphate concentration or temperature, 367 of reaction of flavoenzyme phenol hydroxylases, may be attributable to Balbiani ring induction in phosphate metabolism, 1448 iminol isomers of a flavin-derived 6-arylamino-5-oxo(3H,5H)uracil, 332 Phosphatidic acid Use of riboflavin-binding protein to investigate steric and electronic Angiotensin II rapidly increases phosphatidate-phosphoinositide synthesis relationships in flavin analogs and models, 4246 and phosphoinositide hydrolysis and mobilizes intracellular calcium in Phenotype-genotype interaction cultured arterial muscle cells, 7812 Cultural and biological evolutionary processes: Gene-culture Phosphatidyicholine disequilibrium, 1604 Inhibitors of CDP-choline synthesis, action potential calcium channels, Phenotypic differentiation and stimulus-secretion coupling, 4353 Differential effects of the mottled yellow and pseudoagouti phenotypes on Phosphatidylethanolamine immunocompetence in A'Y/a mice, 2152 Insulin stimulation of phospholipid methylation in isolated rat adipocyte Phenotypic variation plasma membranes, 1089 Snail shape and growth rates: Evidence for plastic shell allometry in pH-sensitive liposomes: Acid-induced liposome fusion, 1715 Littorina littorea, 811 Phosphatidylserine functions as the major precursor of N-Phenylacetyl-L-phenylaianine phosphatidylethanolamine in cultured BHK-21 cells, 2669 Potential use of biaromatic L-phenylalanyl derivatives as therapeutic Phosphatidylinositol agents in the treatment of , 3190 Evidence that the Rous sarcoma virus transforming gene product Phenylalanine ammonia-lyase phosphorylates phosphatidylinositol and diacylglycerol, 2117 Induction of phenylalanine ammonia-lyase and 4-coumarate:CoA ligase Suppression of phagocytic function and phospholipid metabolism in mRNAs in cultured plant cells by UV light or fungal elicitor, 1102 macrophages by phosphatidylinositol liposomes, 2655 L-Phenylaanyl-3-aminopyridine Pharmacomechanical coupling in smooth muscle may involve Potential use of biaromatic L-phenylalanyl derivatives as therapeutic phosphatidylinositol metabolism, 6899 agents in the treatment of sickle cell disease, 3190 Pbosphatidylinositol kinase N,N'-p-Phenylenedimaleimide Transforming protein of avian sarcoma virus UR2 is associated with F-actin is intermolecularly crosslinked by N,N'-p-phenylenedimaleimide phosphatidylinositol kinase activity: Possible role in through lysine-191 and cysteine-374, 6599 tumorigenesis, 2728 Phenylisopropyladenosine Phosphatidylserine Adenosine-dependent activation of tyrosine hydroxylase is defective in Phosphatidylserine functions as the major precursor of adenosine kinase-deficient PC12 cells, 4974 phosphatidylethanolamine in cultured BHK-21 cells, 2669 Pheochromocytoma Phosphatidylserine decarboxylase Chromosome 20 deletion in human multiple endocrine neoplasia types 2A Phosphatidylserine functions as the major precursor of and 2B: A double-blind study, 2525 phosphatidylethanolamine in cultured BHK-21 cells, 2669 Biochemical evidence that vesicles are the source of the acetylcholine Phosphocreatine released from stimulated PC12 cells, 6535 In vivo metabolic effects of hyperglycemia in murine radiation-induced Pheochromocytoma cell fibrosarcoma: A 31P NMR investigation, 6496 Nerve growth factor inhibits the synthesis of a single-stranded DNA binding protein in pheochromocytoma cells (clone PC12), 2080 Rod light response augmented by active phosphodiesterase, 616 Pheromone Pertussis toxin differentiates between two mechanisms of attenuation of A pheromone-induced developmental switch in Caenorhabditis elegans: cyclic AMP accumulation by muscarinic cholinergic receptors, 5680 Temperature-sensitive mutants reveal a wild-type temperature- Phosphoenolpyruvate carboxykinase dependent process, 819 Induction of two genes by glucose starvation in hamster fibroblasts, 988 Molecular cloning of hormone-responsive genes from the yeast Phosphofructokinase Saccharomyces cerevisiae, 1144 Transitions between oscillatory modes in a glycolytic model system, 4394 Soldier formation regulated by a primer pheromone from the soldier Regulation of pea seed pyrophosphate-dependent phosphofructokinase: frontal gland in a higher termite, Nasutitermes lujae, 7665 Evidence for interconversion of two molecular forms as a glycolytic Philadelphia chromosome regulatory mechanism, 5051 An 8-kilobase abl RNA transcript in chronic myelogenous leukemia, 5648 6-Phosphogluconate dehydrogenase Phorbol ester Essential site for growth rate-dependent regulation within the Escherichia Plasma membrane reorganization induced by tumor promoters in an coli gnd structural gene, 7669 epithelial cell line, 449 Phosphoglucose Competitive inhibition by diacylglycerol of specific phorbol ester Further clues concerning the vectors essential to regulation of hexose binding, 607 transport, as studied in fibroblast cultures from a metabolic Association of phorbol ester-induced hyperphosphorylation and reversible mutant, 1126 regulation of membrane receptors in HL60 cells, 2016 Phosphoglycerate kinase Phorbol esters potentiate tyrosine phosphorylation of epidermal growth A human autosomal phosphoglycerate kinase locus maps near the HLA factor receptors in A431 membranes by a calcium-independent cluster, 3167 mechanism, 2298 Phospholnositide Transforming protein of avian sarcoma virus UR2 is associated with Leukotriene B4 mobilizes calcium without the breakdown of phosphatidylinositol kinase activity: Possible role in polyphosphoinositides and the production of phosphatidic acid in rabbit tumorigenesis, 2728 neutrophils, 5966 Tumor-promoting phorbol ester stimulates tyrosine phosphorylation in U- Angiotensin II rapidly increases phosphatidate-phosphoinositide synthesis 937 monocytes, 2762 and phosphoinositide hydrolysis and mobilizes intracellular calcium in Polypeptide hormone regulation of gene transcription: Specific 5' cultured arterial muscle cells, 7812 genomic sequences are required for epidermal growth factor and phorbol ester regulation of prolactin gene expression, 2975 Phospholipase Rapid internalization of the transferrin receptor in K562 cells is triggered Receptor-mediated activation of a in rabbit neutrophil by ligand binding or treatment with a phorbol ester, 3005 plasma membrane, 767 Tumor promoters block tyrosine-specific phosphorylation of the Glucocorticoid-induced phospholipase A2-inhibitory proteins mediate epidermal growth factor receptor, 3034 glucocorticoid teratogenicity in vitro, 1140 Phorbol ester induces desensitization of adenylate cyclase and Time-dependent conversion of a1- to 8-adrenoceptor-mediated phosphorylation of the f3-adrenergic receptor in turkey glycogenolysis in isolated rat liver cells: Role of membrane erythrocytes, 4316 phospholipase A2, 6178 Tumor promoters induce a specific morphological signature in the nuclear Phospholpase A2-inhibitory protein matrix-intermediate filament scaffold of Madin-Darby canine kidney Glucocorticoid-induced phospholipase A2-inhibitory proteins mediate (MDCK) cell colonies, 4409 glucocorticoid teratogenicity in vitro, 1140 Phorbol 12-myristate 13-acetate Phospholipase inhibitory protein Continuous suppression of globin gene expression and differentiation of Phosphorylation at a tyrosine residue of lipomodulin in mitogen- Friend erythroleukemia cells by phorbol 12-myristate 13-acetate (PMA) stimulated murine thymocytes, 4717 despite the loss of PMA binding sites by down regulation, 2075 Phospholipid Induction of plasmacytoid differentiation by phorbol ester in B-cell Role of membrane lipids in peptide hormone function: Binding of lymphoma cell lines bearing 8;14 translocations, 3547 enkephalins to micelles, 61 Suppression of the first stage of phorbol 12-tetradecanoate 13-acetate- Plasma membrane biogenesis in eukaryotic cells: Translocation of newly effected tumor promotion in mouse skin by nontoxic inhibition of DNA synthesized lipid, 1385 synthesis, 5858 The effects of water-soluble solutes on the phase transitions of Phorbol ester, serum, and Rous sarcoma virus transforming gene product phospholipids, 1398 induce similar phosphorylations of ribosomal protein S6, 6408 Modification of low density lipoprotein by endothelial cells involves lipid Phorbol 12-myristate 13-acetate, ionomycin or ouabain, and raised peroxidation and degradation of low density lipoprotein extracellular magnesium induce proliferation of chicken heart phospholipids, 3883 mesenchymal cells, 6418 An Escherichia coli mutant deficient in pyruvate oxidase activity due to Phorbol esters modulate insulin receptor phosphorylation and insulin altered phospholipid activation of the enzyme, 4348 action in cultured hepatoma cells, 7797 Diacylglycerol stimulates DNA synthesis and cell division in mouse 3T3 Phosphatase cells: Role of Ca2-sensitive phospholipid-dependent protein Catalytic site of calmodulin-dependent from bovine kinase, 5748 brain resides in subunit A, 3054 8114 Biological Sciences Subject Index Proc. Natl. Acad. Sci USA 81 (1984)

Calcium/phospholipid-dependent protein kinase (protein kinase C) Cleavage of single-stranded DNA by the 4X174 A* protein: The A*- phosphorylates and activates tyrosine hydroxylase, 7713 single-stranded DNA covalent linkage, 4285 Phospholipid metabolism In vivo effects of microinjected and its low Suppression of phagocytic function and phospholipid metabolism in molecular weight substrates on the first meiotic cell division in macrophages by phosphatidylinositol liposomes, 2655 Xenopus laevis oocytes, 5150 Phospholipid methylation Calmodulin-stimulated phosphorylation of 17,8-estradiol receptor on Insulin stimulation of phospholipid methylation in isolated rat adipocyte tyrosine, 5921 plasma membranes, 1089 Photoaflinity labeling Phospholipid, spin-labeled NAD binding site of diphtheria toxin: Identification of a residue within ATP-dependent asymmetric distribution of spin-labeled phospholipids in the nicotinamide subsite by photochemical modification with the erythrocyte membrane: Relation to shape changes, 3751 NAD, 3307 Phospholipid vesicle Highly selective photoaffinity labeling of At and 8 opioid receptors, 7718 Crambin in phospholipid vesicles: Circular dichroism analysis of crystal Photocyde structure relevance, 1406 A correlation between proton pumping and the bacteriorhodopsin Phosphophoryn photocycle, 7079 Osteonectin, bone proteoglycan, and phosphophoryn defects in a form of Photodlssociation bovine osteogenesis imperfecta, 2213 Comparison of the magnetic properties of deoxy- and photodissociated Phosphoprotein myoglobin, 2359 Phosphoproteins are components of mitotic microtubule organizing Photoinhibitlon centers, 4439 Membrane protein damage and repair: Selective loss of a quinone-protein Phosphoprotein phosphatase function in chloroplast membranes, 4070 Developmental studies of phospholipid-sensitive Ca2'-dependent protein Photolabeling kinase and its substrates and of phosphoprotein in rat Time-resolved photolabeling by the noncompetitive blocker brain, 3143 chlorpromazine of the acetylcholine receptor in its transiently open and Phosphorus closed ion channel conformations, 1897 Complex carbohydrate diets are not capable of maintaining normal PhotomorphogpneIs plasma calcium and phosphorus levels in vitamin D-deficient rats, 2352 Indole-3-acetic acid sensitization of phytochrome-controlled growth of coleoptile sections, 3742 Phosphorylated antigen in Induction of tubulins and Somatic mutation of the T15 heavy chain gives rise to an antibody with Photomorphogenesis Physarum: sporulation- autoantibody specificity, 5841 specific proteins and of their mRNAs, 7117 Photoperiod Phosphorylation In vitro reprogramming of the photoperiodic clock in an insect brain- Mechanism of translational control by partial phosphorylation of the a subunit of eukaryotic initiation factor 2, 352 retrocerebral complex, 5881 Kindling alters the calcium/calmodulin-dependent phosphorylation of Photophosphorylation synaptic plasma membrane proteins in rat hippocampus, 1253 Partial deglycosylation of chloroplast coupling factor 1 (CF1) prevents the Biologically active synthetic fragments of epidermal growth factor: reconstitution of photophosphorylation, 3733 Localization of a major receptor-binding region, 1351 Evidence that phosphorylation and dephosphorylation regulate the Rod light response augmented by active phosphodiesterase, 616 distribution of excitation energy between the two photosystems of Sensitive light scattering probe of enzymatic processes in retinal rod photosynthesis in vivo: Photoacoustic and fluorimetric study of an photoreceptor membranes, 743 intact leaf, 1614 Molecular cloning of cDNA for Avena phytochrome, 2332 Progesterone receptor subunits are high-affinity substrates for Squid rhodopsin and GTP-binding protein crossreact with vertebrate phosphorylation by epidermal growth factor receptor, 1654 photoreceptor enzymes, 5111 Association of phorbol ester-induced hyperphosphorylation and reversible Isolation and characterization of a cDNA clone for the -y subunit of regulation of transferrin membrane receptors in HL60 cells, 2016 bovine retinal transducin, 6948 Evidence that the Rous sarcoma virus transforming gene product y-Aminobutyric acid acts at axon terminals of turtle photoreceptors: phosphorylates phosphatidylinositol and diacylglycerol, 2117 Difference in sensitivity among cell types, 7961 Membranes from T and B lymphocytes have different patterns of tyrosine Photoreduction phosphorylation, 2347 Photoreduction of ferredoxin with various electron donors: Support for Autophosphorylation of v-Ha-ras p21 is modulated by amino acid residue the Z scheme of photosynthetic electron transport, 2070 12, 2674 Photosensitization Tumor-promoting phorbol ester stimulates tyrosine phosphorylation in U- Selective killing of leukemic cells by merocyanine 540-mediated 937 monocytes, 2762 photosensitization, 7584 Defining erythrocyte internal labeling by phosphorylation, 2767 Photosynthesis Inhibition by calmodulin of calcium/phospholipid-dependent protein Tunneling in Chromatium chromatophores: Detection of a Hopfield phosphorylation, 3622 charge-transfer band, 135 Phorbol ester induces desensitization of adenylate cyclase and Reaction center and light-harvesting I genes from Rhodopseudomonas phosphorylation of the /3-adrenergic receptor in turkey capsulata, 189 erythrocytes, 4316 Electron nuclear double resonance evidence supporting a monomeric Protein synthesis in rabbit reticulocytes: A study of the mechanism of nature for P700+ in spinach chloroplasts, 1098 action of the protein factor RF that reverses protein synthesis inhibition Charge accumulation and photochemistry in leaves studied by of -deficient reticulocyte lysates, 5379 thermoluminescence and delayed light emission, 1107 Immunocytochemical localization of calcium/calmodulin-dependent Structural studies of the primary donor cation radical P 0 in reaction protein kinase II in rat brain, 5604 centers of Rhodospirillum rubrum by electron-nuclear double Heterogeneity of microtubule-associated protein 2 during rat brain resonance in solution, 1401 development, 5613 Evidence that phosphorylation and dephosphorylation regulate the Intrinsic GTPase activity distinguishes normal and oncogenic ras p21 distribution of excitation energy between the two photosystems of molecules, 5704 photosynthesis in vivo: Photoacoustic and fluorimetric study of an Linear organization of the liver cell adhesion molecule L-CAM, 5787 intact leaf, 1614 Calmodulin-stimulated phosphorylation of 17f3-estradiol receptor on Photoreduction of ferredoxin with various electron donors: Support for tyrosine, 5921 the Z scheme of photosynthetic electron transport, 2070 Phorbol ester, serum, and Rous sarcoma virus transforming gene product Effects of Cu deficiency on photosynthetic electron transport, 2369 induce similar phosphorylations of ribosomal protein S6, 6408 NMR study of chloride ion interactions with thylakoid membranes, 3713 Phosphorylation of the nicotinic acetylcholine receptor by an endogenous Membrane protein damage and repair: Selective loss of a quinone-protein tyrosine-specific protein kinase, 6968 function in chloroplast membranes, 4070 Electrical stimulation increases phosphorylation of tyrosine hydroxylase Crystallization of reaction center from Rhodopseudomonas sphaeroides: in superior cervical ganglion of rat, 7243 Preliminary characterization, 4795 Effects of in vivo-administered 2,3,7,8-tetrachlorodibenzo-p-dioxin on Triazine herbicide resistance in the photosynthetic bacterium receptor binding of epidermal growth factor in the hepatic plasma Rhodopseudomonas sphaeroides, 6310 membrane of rat, guinea pig, mouse, and hamster, 7407 Primary structure of the L subunit of the reaction center from myo-Inositol 1,4,5-trisphosphate stimulates protein phosphorylation in Rhodopseudomonas sphaeroides, 7303 saponin-permeabilized human platelets, 7431 5N electron nuclear double resonance of the primary donor cation radical Identification of the at3 monomer of the adipocyte insulin receptor by P+ in reaction centers of Rhodopseudomonas sphaeroides: Additional insulin binding and autophosphorylation, 7693 evidence for the dimer model, 7792 Phorbol esters modulate insulin receptor phosphorylation and insulin Genes for the a and ,B subunits of phycocyanin, 7946 action in cultured hepatoma cells, 7797 Photosysteem Phosphoserine Electron nuclear double resonance evidence supporting a monomeric Balbiani ring induction in phosphate metabolism, 1448 nature for P700+ in spinach chloroplasts, 1098 Linear organization of the liver cell adhesion molecule L-CAM, 5787 Regulation of protein metabolism: Coupling of photosynthetic electron Specific in vitro adenylylation of the simian virus 40 large tumor transport to in vivo degradation of the rapidly metabolized 32-kilodalton antigen, 6574 protein of the chloroplast membranes, 1380 Phosphothreonine Evidence that phosphorylation and dephosphorylation regulate the Linear organization of the liver cell adhesion molecule L-CAM, 5787 distribution of excitation energy between the two photosystems of Phosphotyrosine photosynthesis in vivo: Photoacoustic and fluorimetric study of an Progesterone receptor subunits are high-affinity substrates for intact leaf, 1614 phosphorylation by epidermal growth factor receptor, 1654 Effects of Cu deficiency on photosynthetic electron transport, 2369 Membranes from T and B lymphocytes have different patterns of tyrosine Nucleotide sequence of a multiple-copy gene for the B protein of phosphorylation, 2347 photosystem II of a cyanobacterium, 2693 Biological Sciences Subject Index Proc. Natl. Acad. Sci. USA 81 (1984) 8115

Cooperative transient trapping of photosystem II protons by the integral Placenta membrane portion (CFO) of chloroplast ATP-synthase after mild Increased rates of polypeptide chain elongation in placental explants from extraction of the four-subunit catalytic part (CF1), 3078 human diabetics, 1366 Herbicide resistance in Chlamydomonas reinhardtii results from a Eutherian-like reproductive specializations in a viviparous reptile, 4860 mutation in the chloroplast gene for the 32-kilodalton protein of Human placental syncytiotrophoblastic Mr 75,000 polypeptide defined by photosystem II, 3617 antibodies to a synthetic peptide based on a cloned human endogenous Phototropic response retroviral DNA sequence, 6197 Phototropic response of the stage I Phycomyces sporangiophore to a Calcium-dependent, cyclic nucleotide-independent steroidogenesis in the pulse of blue light, 7103 bovine placenta, 6403 Phycobiliprotein Detection and immunochemical characterization of a primate type C Cloning and sequencing of the genes encoding the a and /3 subunits of C- retrovirus-related p30 protein in normal human placentas, 6501 phycocyanin from the cyanobacterium Agmenellum Placental activator quadruplicatum, 6983 A placental polypeptide activator of a membranous protein kinase and its Phycobilisome relation to histone 1, 7388 Isolation and characterization of a gene for a major light-harvesting Placental lactogen polypeptide from Cyanophora paradoxa, 4100 Placental lactogen administration reverses the effect of low-protein diet Genes for the a and subunits of phycocyanin, 7946 on maternal and fetal serum somatomedin levels in the pregnant Phycocyamni rat, 5853 Cloning and sequencing of the genes encoding the a and subunits of C- Planar membrane phycocyanin from the cyanobacterium Agmenellum Allogeneic stimulation of cytotoxic T cells by supported planar quadruplicatum, 6983 membranes, 6159 Genes for the a and /8 subunits of phycocyanin, 7946 Different channel properties of Torpedo acetylcholine receptor monomers /-Phycocyanin and dimers reconstituted in planar membranes, 6222 Isolation and characterization of a gene for a major light-harvesting Plant polypeptide from Cyanophora paradoxa, 4100 Tubulins from different higher plant species are immunologically Phycomyces nonidentical and bind colchicine differentially, 1440 Phototropic response of the stage I Phycomyces sporangiophore to a Extensive and widespread homologies between mitochondrial DNA and pulse of blue light, 7103 chloroplast DNA in plants, 1946 Phylogeny Plant cell Natural interspecies transfer of mitochondrial DNA in amphibians, 5802 Induction of phenylalanine ammonia-lyase and 4-coumarate:CoA ligase Physarum mRNAs in cultured plant cells by UV light or fungal elicitor, 1102 Relationships between the structures of taxol and baccatine III Plant cell membrane derivatives and their in vitro action on the disassembly of mammalian Isoelectric focusing of plant cell membranes, 4804 brain and Physarum amoebal microtubules, 4090 Plant parasite Invariant temporal order of replication of the four actin gene loci during Cloning and structure determination of cDNA for , an enzyme the naturally synchronous mitotic cycles of Physarum involved in fungal penetration of plants, 3939 polycephalum, 6393 Plant-parasite interaction Photomorphogenesis in Physarum: Induction of tubulins and sporulation- Cloned avirulence gene of Pseudomonas syringae pv. glycinea specific proteins and of their mRNAs, 7117 determines race-specific incompatibility on Glycine max (L.) Phytoalexin Merr., 6024 Differential induction of chalcone synthase mRNA activity at the onset of Plant pathogen phytoalexin accumulation in compatible and incompatible plant- Differential induction of chalcone synthase mRNA activity at the onset of pathogen interactions, 3384 phytoalexin accumulation in compatible and incompatible plant- Elicitor rapidly induces chalcone synthase mRNA in Phaseolus vulgaris pathogen interactions, 3384 cells at the onset of the phytoalexin defense response, 5724 Plant tumorigenesis Phytochrome Nucleotide sequence of the tms genes of the pTiA6NC octopine Ti Demonstration of transcriptional regulation of specific genes by plasmid: Two gene products involved in plant tumorigenesis, 1728 phytochrome action, 1112 Plant virus Molecular cloning of cDNA for Avena phytochrome, 2332 Multicomponent RNA plant virus infection derived from cloned viral Indole-3-acetic acid sensitization of phytochrome-controlled growth of cDNA, 7066 coleoptile sections, 3742 Plant wound Modulation of chloroplast movement in the green alga Mougeotia by the Wound signals in plants: A systemic plant wound signal alters plasma Ca2+ ionophore A23187 and by calmodulin antagonists, 6368 membrane integrity, 3737 Phytophthora Plaque Induction of phenylalanine ammonia-lyase and 4-coumarate:CoA ligase Localization of the gangliosides GD2 and GD3 in adhesion plaques and on mRNAs in cultured plant cells by UV light or fungal elicitor, 1102 the surface of human melanoma cells, 5767 Pilus Plasma Pilus genes of Neisseria gonorrheae: Chromosomal organization and Inhibition of the mitogenic effects of plasma by a monoclonal antibody to DNA sequence, 6110 somatomedin C, 2389 Pindolol Plasma cell Quantitative autoradiography of,B- and 832-adrenergic receptors in rat Immunoglobulin heavy chain toxicity in plasma cells is neutralized by brain, 1585 fusion to pre-B cells, 7185 Pisum Plasma membrane Alkane biosynthesis by decarbonylation of aldehydes catalyzed by a Plasma membrane reorganization induced by tumor promoters in an particulate preparation from Pisum sativum, 6613 epithelial cell line, 449 Pituitary Receptor-mediated activation of a phospholipase A2 in rabbit neutrophil Estradiol feedback effects on the a-subunit mRNA in the sheep pituitary plasma membrane, 767 gland: Correlation with serum and pituitary luteinizing hormone Monoclonal antibodies detect a spectrin-like protein in normal and concentrations, 1322 dystrophic human skeletal muscle, 776 Carboxypeptidase B-like converting enzyme activity in secretory granules Insulin stimulation of phospholipid methylation in isolated rat adipocyte of rat pituitary, 2776 plasma membranes, 1089 Properties of rat anterior pituitary vasopressin receptors: Relation to Goblin (ankyrin) in striated muscle: Identification of the potential adenylate cyclase and the effect of corticotropin-releasing factor, 2907 membrane receptor for erythroid spectrin in muscle cells, 3292 Isolation, primary structure, and synthesis of human hypothalamic Identification of a 34,000-dalton mitogenic protein associated with plasma somatocrinin: Growth hormone-releasing factor, 4302 membranes from human A431 epidermoid carcinoma cells, 3399 Direct arterial vascularization of estrogen-induced prolactin-secreting Wound signals in plants: A systemic plant wound signal alters plasma anterior pituitary tumors, 4549 membrane integrity, 3737 Isolation and partial molecular characterization of pituitary fibroblast Nonenzymic ADP-ribosylation of specific mitochondrial growth factor, 5364 polypeptides, 3929 Isolation of brain fibroblast growth factor by heparin-Sepharose affinity New protein kinase from plasma membrane of Ehrlich ascites tumor cells chromatography: Identity with pituitary fibroblast growth factor, 6963 activated by natural polypeptides, 4250 Regional distribution of putative vasopressin receptors in rat brain and Isoelectric focusing of plant cell membranes, 4804 pituitary by quantitative autoradiography, 7248 Lamellar-to-hexogonal1j phase transitions in the plasma membrane of Pituitary-adrenal system isolated protoplasts after freeze-induced dehydration, 6373 RU 486: A steroid with antiglucocorticosteroid activity that only Loss of reciprocal modulations of growth and liver function of hepatoma disinhibits the human pituitary-adrenal system at a specific time of cells in culture by contact with cells or cell membranes, 6398 day, 3879 Isolation, purification, and reconstitution of the Na+ gradient-dependent Pitudtary cell Ca2+ transporter (Na+-Ca + exchanger) from brain synaptic plasma Growth hormone-releasing factor regulates growth hormone mRNA in membranes, 6521 primary cultures of rat pituitary cells, 1553 The cromolyn binding protein constitutes the Ca2+ channel of basophils Pituitary extract opening upon immunological stimulus, 6841 Serum-free growth of human mammary epithelial cells: Rapid clonal Effects of in vivo-administered 2,3,7,8-tetrachlorodibenzo-p-dioxin on growth in defined medium and extended serial passage with pituitary receptor binding of epidermal growth factor in the hepatic plasma extract, 5435 membrane of rat, guinea pig, mouse, and hamster, 7407 Pituitary hormone In vitro translocation of bacterial proteins across the plasma membrane of Glycosylated ovine prolactin, 385 Escherichia coli, 7421 8116 Biological Sciences Subject Index Proc. NatL. Acad. Sci. USA 81 (1984)

Plasma membrane biogenesis Differential antibody screening of cloned Plasmodium falciparum Plasma membrane biogenesis in eukaryotic cells: Translocation of newly sequences expressed in Escherichia coli: Procedure for isolation of synthesized lipid, 1385 defined antigens and analysis of human antisera, 2456 Plasma membrane protein Identification and expression in Escherichia coli of merozoite stage- Kindling alters the calcium/calmodulin-dependent phosphorylation of specific genes of the human malarial parasite Plasmodium synaptic plasma membrane proteins in rat hippocampus, 1253 falciparum, 3690 Plasmacytoma Circumsporozoite gene of Plasmodium cynomolgi (Gombak): cDNA Products of a reciprocal chromosome translocation involving the c-myc cloning and expression of the repetitive circumsporozoite epitope, 7520 gene in a murine plasmacytoma, 829 Human antibodies to a Mr 155,000 Plasmodium falciparum antigen Plasmid efficiently inhibit merozoite invasion, 7912 An immune strain of Halobacterium halobium carries the invertible L Plasticity segment of phage 4)H as a plasmid, 1017 Determination of synaptic phenotype: Insulin and cAMP independently Transformation of Aspergillus nidulans by using a trpC plasmid, 1470 initiate development of electrotonic coupling between cultured Efficient coupled transcription and mRNA splicing in vitro using plasmids sympathetic neurons, 6235 derived from early region 3 of adenovirus 2 and a nondefective Platelet adenovirus-simian virus 40 hybrid, 2679 12S,20-Dihydroxyicosatetraenoic acid: A new icosanoid synthesized by Homologous recombination between plasmids in mammalian cells can be neutrophils from 12S-hydroxyicosatetraenoic acid produced by enhanced by treatment of input DNA, 3153 thrombin- or collagen-stimulated platelets, 903 A cis-acting element from the Epstein-Barr viral genome that permits ADP-dependent common receptor mechanism for binding of von stable replication of recombinant plasmids in latently infected Willebrand factor and t? human platelets, 4935 cells, 3806 Specific binding to cultured cells of'2 I-labeled type , transforming Isolation of the yeast INOI gene: Located on an autonomously growth factor from human platelets, 6757 replicating plasmid, the gene is fully regulated, 3816 myo-Inositol 1,4,5-trisphosphate stimulates protein phosphorylation in Regulation of bacterial DNA supercoiling: Plasmid linking numbers vary saponin-permeabilized human platelets, 7431 with growth temperature, 4046 Platelet-activing factor Plasmid CoIEl Human endothelial cells in culture produce platelet-activating factor Escherichia coli mutants suppressing replication-defective mutations of (1-alkyl-2-acetyl-sn-glycero-3-phosphocholine) when stimulated with the ColEl plasmid, 550 thrombin, 3534 Escherichia coli mutants suppressing replication-defective mutations of Platelet-derived growth factor the ColEl plasmid (Correction), 2944 Specific covalent binding of platelet-derived growth factor to human Plasmid complementation plasma a2-, 342 Analysis of the pleiotropic regulation of flagellar and chemotaxis gene A glioma-derived analog to platelet-derived growth factor: Demonstration expression in Caulobacter crescentus by using plasmid of receptor competing activity and immunological crossreactivity, 926 complementation, 1341 Production of platelet-derived growth factor-like molecules and reduced Plasmid F expression of platelet-derived growth factor receptors accompany Virus-plasmid interactions: Mutants of bacteriophage T3 that abortively transformation by a wide spectrum of agents, 23% strains of Escherichia coli, 1465 Specific covalent binding of platelet-derived growth factor to human infect plasmid F-containing (F+) plasma a2-macroglobulin (Correction), 2586 Plasmid mobIlItion Plasma binding proteins for platelet-derived growth factor that inhibit its Plasmid-linked nif and "nod" genes in fast-growing rhizobia that nodulate binding to cell-surface receptors, 3424 Glycine max, Psophocarpus tetragonolobus, and Vigna Expression of the sis gene by endothelial cells in culture and in vivo, 6772 unguiculata, 3093 Blockade of autocrine stimulation in simian sarcoma virus-transformed Plasmid, multicopy cells reverses down-regulation of platelet-derived growth factor Spontaneous and mutagen-induced deletions: Mechanistic studies in receptors, 7466 Salmonella tester strain TA102, 4457 Platelet-derived growth factor receptor Plasmid P1 Production of platelet-derived growth factor-like molecules and reduced Plasmid P1 replication: Negative control by repeated DNA expression of platelet-derived growth factor receptors accompany sequences, 6456 transformation by a wide spectrum of agents, 23% Plasmid pBR322 Plelotropic regulation A pattern of partially homologous recombination in mouse L cells, 206 Analysis of the pleiotropic regulation of flagellar and chemotaxis gene Microinjected pBR322 stimulates cellular DNA synthesis in Swiss 3T3 expression in Caulobacter crescentus by using plasmid cells, 400 complementation, 1341 DNA methylation pattern is determined by the intracellular level of the methylase, 3278 Pleistocene The absence of RNase H allows replication of pBR322 in Escherichia coli Guatemalan forest synthesis after Pleistocene aridity, 4856 mutants lacking DNA polymerase I, 7845 Poky mutant The [poky] mutant of Neurospora contains a 4-base-pair deletion at the 5' Plasmid R100 end of the mitochondrial small rRNA, 3791 Mercuric ion-resistance operons of plasmid R100 and transposon Tn501: Polar membrane The beginning of the operon including the regulatory region and the Isolation of flagellated membrane vesicles from Caulobacter crescentus first two structural genes, 5975 cells: Evidence for functional differentiation of polar membrane Plasmid replication 3409 cis-acting mutations that affect rop protein control of plasmid copy domains, number, 4465 Polar transport Plasmid replicon Isoelectrnc focusing of plant cell membranes, 4804 In vivo DNA cloning and adjacent gene fusing with a mini-Mu-lac Polioirus bacteriophage containing a plasmid replicon, 1480 Comparison of the complete nucleotide sequences of the genomes of the Plasmid RK2 neurovirulent poliovirus P3/Leon/37 and its attenuated Sabin vaccine Plasmid transfer from Escherichia coli to Bacteroides fragilis: Differential derivative P3/Leon 12alb, 1539 expression of resistance phenotypes, 7203 Pollination Plasmid, RNA Estimation of mating system parameters when outcrossing events are Specificity of polyamine requirements for the replication and maintenance correlated, 5258 of different double-stranded RNA plasmids in Saccharomyces Poly(A)+ RNA Identification and primary sequence of an unspliced human urokinase cerevisiae, 1149 poly(A)+ RNA, 4727 Plasmid RSF1010 of xeroderma cells Replication of the broad host range plasmid RSF1010: Requirement for Transient complementation pigmentosum by three plasmid-encoded proteins, 654 microinjection of poly(A)+ RNA, 5676 Plasmid transfer Polyadenylylation Plasmid transfer from Escherichia coli to Bacteroides fragilis: Differential Requirement for the 3' flanking region of the bovine growth hormone expression of antibiotic resistance phenotypes, 7203 gene for accurate polyadenylylation, 3944 Plasminogen Polyadenylylation site Schwann cell proliferation and localized proteolysis: Expression of Structure of a human gastrin gene, 1067 plasminogen-activator activity predominates in the proliferating cell Poly(ADP-ribose) 7216 Inhibition of malignant transformation in vitro by inhibitors of poly(ADP- populations, ribose) synthesis, 243 activator of Monoclonal antibodies to human urokinase identify the single-chain pro- Induction of murine teratocarcinoma cell differentiation by suppression urokinase precursor, 110 poly(ADP-ribose) synthesis, 7132 Identification and primary sequence of an unspliced human urokinase Polyamine 4727 Specificity of polyamine requirements for the replication and maintenance poly(A)+ RNA, RNA in Plamnogen activator gene of different double-stranded plasmids Saccharomyces The structure of the human tissue-type plasminogen activator gene: cerevisiae, 1149 Correlation of intron and exon structures to functional and structural Polyamine metabolism domains, 5355 Assignment of the gene for methylthioadenosine phosphorylase to human Plasmodium chromosome 9 by mouse-human somatic cell hybridization, 2665 Protective immunization of the squirrel monkey against asexual blood Polycyclic aromatic hydrocarbon stages of Plasmodium falciparum by use of parasite protein Polycyclic aromatic hydrocarbon mutagenesis of human epidermal fractions, 229 keratinocytes in culture, 7802 Biological Sciences Subject Index Proc. Natl. Acad. Sci. USA 81 (1984) 8117

Polyelectrolyte Portage Measurement of the repulsive force between polyelectrolyte molecules in Portage of various compounds into bacteria by attachment to glycine ionic solution: Hydration forces between parallel DNA double residues in peptides, 4573 helices, 2621 Positional specificity Statistical mechanics of the B -* Z transition of DNA: Contribution of Related cell-surface antigens expressed with positional specificity in diffuse ionic interactions, 5116 Drosophila imaginal discs, 7485 Polygene Positive regulation Trypanosome variant-specific : A polygene protein family An operator at -280 base pairs that is required for repression of araBAD with multiple folding patterns?, 998 operon promoter: Addition of DNA helical turns between the operator Polygenic trait and promoter cyclically hinders repression, 5017 Group selection for a polygenic behavioral trait: Estimating the degree of Post-synaptic density population subdivision, 6073 Ca2+/calmodulin-dependent protein kinases from the neuronal nuclear Polykaryon matrix and post-synaptic density are structurally related, 4311 Recombinant human t-interferon induces human monocyte polykaryon Post-translational modification formation, 4554 Human pancreatic icosapeptide: Isolation, sequence, and Polymorphism immunocytochemical localization of the COOH-terminal fragment of Molecular abnormality of an inactive aldehyde dehydrogenase variant the pancreatic polypeptide precursor, 708 commonly found in Orientals, 258 Molecular weight and structural nonequivalence of the mature a subunits Patterns of polymorphism and linkage disequilibrium suggest independent of Torpedo californica acetylcholine receptor, 2631 origins of the human growth hormone gene cluster, 6085 Sulfation of lutropin oligosaccharides with a cell-free system, 5320 Characterization of a human liver cytochrome P-450 involved in the Amino acid sequence and post-translational modification of human oxidation of debrisoquine and other drugs by using antibodies raised to interleukin 2, 6486 the analogous rat enzyme, 7348 Enzymes processing somatostatin precursors: An Arg-Lys Polyneuropathy esteropeptidase from the rat brain cortex converting somatostatin-28 Primary structure of an prealbumin and its plasma precursor in a into somatostatin-14, 6662 heredofamilial polyneuropathy of Swedish origin, 694 Synthesis and glycosylation of the common a subunit of human Polynomial model glycoprotein hormones in mouse cells, 6701 Evolutionary principles for polynomial models of frequency-dependent Posterior pituitary selection, 2840 Method for quantitating the molecular content of a subcellular organelle: Polynucleotide kinase Hormone and neurophysin content of newly formed and aged Heat-labile alkaline phosphatase from Antarctic bacteria: Rapid 5' end- neurosecretory granules, 180 labeling of nucleic acids, 6691 Posts tic density Polyoma virus Selective association of N-methyl aspartate and quisqualate types of L- Transformation by polyoma virus is drastically reduced by substitution of glutamate receptor with brain postsynaptic densities, 6876 phenylalanine for tyrosine at residue 315 of middle-size tumor Posture antigen, 679 Motor deficits in patients with large-fiber sensory neuropathy, 979 Expression of an immunoglobulin heavy chain gene transfected into Potassium lymphocytes, 1292 Artifacts caused by cell microinjection, 1426 DNA binding activity of polyoma virus large tumor antigen, 1941 Potassium channel obl7 cells transformed by the middle-T-only gene of polyoma virus Activation of Ca-dependent K channels by carbamoylcholine in rat differentiate in vitro and in vivo into adipose cells, 5440 lacrimal glands, 611 Regulation of polyomavirus transcription by large tumor antigen, 6919 Single channel recordings of calcium-activated potassium channels in the Direct transfection of viral and plasmid DNA into the liver or spleen of apical membrane of rabbit cortical collecting tubules, 4237 mice, 7529 The presence of pig brain of an endogenous equivalent of apamin, the bee Polypeptide activator venom peptide that specifically blocks Ca24-dependent K+ New protein kinase from plasma membrane of Ehrlich ascites tumor cells channels, 7228 activated by natural polypeptides, 4250 Two endogenous neuropeptides modulate the gill and siphon withdrawal Polypeptide chain elongation reflex in Aplysia by presynaptic facilitation involving cAMP-dependent Increased rates of polypeptide chain elongation in placental explants from closure of a serotonin-sensitive potassium channel, 7956 human diabetics, 1366 Potassium conductance Polypeptide degradation Development of a delayed outward-rectifying K+ conductance in cultured Multiple joined genes prevent product degradation in Escherichia mouse peritoneal macrophages, 3083 coli, 4627 Cell swelling increases a barium-inhibitable potassium conductance in the Polypeptide, synthetic basolateral membrane of Necturus small intestine, 3591 Genetic control of major histocompatibility complex-linked immune Potassium transport responses to synthetic polypeptides in man: Poly(L-phenylalanine, Sequence homology between two membrane transport ATPases, the Kdp- L-glutamic acid)-poly(DL-alanine)--poly(L-lysine) and L-glutamic acid, ATPase of Escherichia coli and the Ca2+-ATPase of sarcoplasmic L-alanine, L-tyrosine (60:30:10), 3521 reticulum, 4746 Poly(rG-dC)-poly(rG-dC) Potato Salt-induced Z-A-Z transition sequence in the mixed ribo-deoxyribo Wound signals in plants: A systemic plant wound signal alters plasma copolymer poly(rG-dC)-poly(rG-dC), 7284 membrane integrity, 3737 Polysaccharide Poxvfrus Cross-reactions of polysaccharides of fungi, molds, and yeasts in anti- Construction of live vaccines using genetically engineered poxviruses: pneumococcal and other antisera, 5247 Biological activity of vaccinia virus recombinants expressing the Poly(sialic acid) hepatitis B virus surface antigen and the herpes simplex virus Use of prokaryotic-derived probes to identify poly(sialic acid) in neonatal glycoprotein D, 193 neuronal membranes, 1971 Pre-B oell Polysiphonia Allelic inclusion in the pre-B-cell line 18-81, 867 Transfer of nuclei from a parasite to its host, 5420 Immunoglobulin heavy chain toxicity in plasma cells is neutralized by Polysome fusion to pre-B cells, 7185 Synthesis of a major integral membrane protein polypeptide of rat liver Preadipocyte peroxisomes on free polysomes, 7127 Growth hormone promotes the differentiation of myoblasts and Population genetics preadipocytes generated by azacytidine treatment of 10T½/2 cells, 3429 Evolutionary principles for polynomial models of frequency-dependent Prealbumin selection, 2840 Primary structure of an amyloid prealbumin and its plasma precursor in a Evolution of multigene families under interchromosomal gene heredofamilial polyneuropathy of Swedish origin, 694 conversion, 3796 Preapolipoprotein Population structure Human apolipoprotein C-II: Complete nucleic acid sequence of Evidence for clinal population structure in Escherichia coli, 198 preapolipoprotein C-II, 6354 Group selection for a polygenic behavioral trait: Estimating the degree of Precursor cleavage population subdivision, 6073 Biologically active protease of foot and mouth disease virus is expressed Pore from cloned viral cDNA in Escherichia coli, 3351 Movement of ions through fixed pores in the neural membrane, 5609 Precursor protein A "convertible pore" model of neural membrane conductance, 7238 Evidence for an intracellular precursor for human B-cell growth Pore formation factor, 7902 Mechanism of insertion of diphtheria toxin: Peptide entry and pore size Precursor RNA determinations, 3341 Chloroplast tRNAGY gene contains a long intron in the D stem: Porin Nucleotide sequences of tobacco chloroplast genes for tRNAGlY (UCC) Amino acid sequence homology among the major outer membrane and tRNAArs (UCU), 405 proteins of Escherichia coli, 1048 Predator Porphobilinogen deaminase Trophic links of community food webs, 4105 Molecular cloning of a cDNA sequence complementary to Predator-prey interaction porphobilinogen deaminase mRNA from rat, 5036 Spider sedation induced by defensive chemicals of milliped prey, 806 Porphyria Prganacy Isolation and identification of a cDNA clone coding for rat Placental lactogen administration reverses the effect of low-protein diet uroporphyrinogen decarboxylase, 3346 on maternal and fetal serum somatomedin levels in the pregnant rat, 5853 8118 Biological Sciences Subject Index Proc. NatL Acad. ScL USA 81 (1984)

Pregnancy zone protein Multiple joined genes prevent product degradation in Escherichia Partial primary structure of human pregnancy zone protein: Extensive coli, 4627 sequence homology with human a2-macroglobulin, 7353 (Pro)insulin associates with Golgi membranes of pancreatic B cells, 6743 Prelysosomal structure Prokaryotic differentiation Two populations of prelysosomal structures transporting Rhizobium free-living nitrogen fixation occurs in specialized nongrowing in rat liver, 2995 cells, 1566 Preprocholecystokinin Prolactin Cloning and sequence analysis of a cDNA encoding rat Glycosylated ovine prolactin, 385 preprocholecystokinin, 726 Growth hormone-releasing factor regulates growth hormone mRNA in Cloned cDNA to cholecystokinin mRNA predicts an identical primary cultures of rat pituitary cells, 1553 preprocholecystokinin in pig brain and gut, 4307 Polypeptide hormone regulation of gene transcription: Specific 5' Preproenkephalin genomic sequences are required for epidermal growth factor and Denervation of rat adrenal glands markedly increases preproenkephalin phorbol ester regulation of prolactin gene expression, 2975 mRNA, 7221 Nucleotide sequence of a growth-related mRNA encoding a member of Molecular cloning and sequence determination of rat preproenkephalin the prolactin-growth hormone family, 4255 cDNA: Sensitive probe for studying transcriptional changes in rat Direct arterial vascularization of estrogen-induced prolactin-secreting tissues, 7651 anterior pituitary tumors, 4549 Preproinsulin Mapping-of N6-methyladenosine residues in bovine prolactin Cell-specified expression of a selectable hybrid gene, 4657 mRNA, 5667 Guinea pig preproinsulin gene: An evolutionary compromise?, 5046 Physiological role of a-melanocyte-stimulating hormone in modulating the Preproneuropeptide Y secretion of prolactin and luteinizing hormone in the female rat, 8004 Cloning, characterization, and DNA sequence of a human cDNA Proliferin encoding neuropeptide tyrosine, 4577 Nucleotide sequence of a growth-related mRNA encoding a member of Preproparathyroid hormone the prolactin-growth hormone family, 4255 Secretion of human parathyroid hormone from rat pituitary cells infected Proline with a recombinant retrovirus encoding preproparathyroid Detection of cis and trans X-Pro peptide bonds in proteins by 13C NMR: hormone, 5340 Application to collagen, 4800 Preprosomatostatin Abnormal collagen metabolism in cultured skin fibroblasts from patients Primary structure of the gene encoding rat preprosomatostatin, 3337 with Duchenne muscular dystrophy, 5130 Presequence Proline-rich protein Isolation and characterization of a cDNA clone for bovine cytochrome c Clones from the human gene complex coding for salivary proline-rich oxidase subunit IV, 6295 proteins, 5561 Presynaptic filament Prolipoprotein Isolation and visualization of active presynaptic filaments of recA protein Nucleotide sequence of the Escherichia coli prolipoprotein signal and single-stranded DNA, 7026 peptidase (Isp) gene, 3708 Promoter Prey Mapping of the late promoter of simian virus 40, 23 Trophic links of community food webs, 4105 Determination of the promoter region of mouse ribosomal RNA gene by Primate an in vitro transcription system, 299 Linkage disequilibrium and evolutionary relationships of DNA variants Stimulation of in vitro transcription from heterologous promoters by the ( fragment length polymorphisms) at the serum simian virus 40 enhancer, 308 albumin locus, 3486 Use of the Escherichia coli lac repressor and operator to control gene Carotenoids and retinol: Their possible importance in determining expression in Bacillus subtilis, 439 longevity of primate species, 7627 Transcripts of human HLA gene fragments lacking the S'-terminal region Pro-opiomelanocortin in transfected mouse cells, 649 Expression of pro-opiomelanocortin-like gene in the testis and Promoter-regulatory region of the major immediate early gene of human epididymis, 5672 cytomegalovirus, 659 Procollagen Generation of a Tn5 promoter probe and its use in the study of gene Endonuclease S1-sensitive site in chicken pro-a2(I) collagen 5' flanking expression in Caulobacter crescentus, 1035 gene region, 1659 The subtilisin E gene of Bacillus subtilis is transcribed from a 37 Cathepsin D-mediated processing of procollagen: Lysosomal enzyme promoter in vivp, 1184 involvement in secretory processing Qf procollagen, 3302 Contact points between transcription machinery and the fibroin gene Nuclease S1 mapping of a homozygous mutation in the carboxyl- promoter deduced by functional tests of single-base substitution propeptide-coding region of the proa2(I) collagen gene in a patient with mutants, 1394 osteogenesis imperfecta, 4524 High-level expression of a chemically synthesized gene for human Prodrug interferon-y using a prokaryotic expression vector, 2290 6-Deoxyacyclovir: A xanthine oxidase-activated prodrug of Determination of the promoter region of mouse ribosomal RNA gene by acyclovir, 3209 an in vitro transcription system (Correction), 2587 Prodyrnorphin Structure of the 5' ends of immunoglobulin genes: A novel conserved Differential processing of prodynorphin and proenkephalin in specific sequence, 2650 regions of the rat brain, 6886 Dictyostelium transposable element DIRS-1 has 350-base-pair inverted Proenkephalin terminal repeats that contain a heat shock promoter, 2660 Changes in rat adrenal catecholamines and proenkephalin metabolism DNA methylation of three 5' C-C-G-G 3' sites in the promoter and 5' after denervation, 3587 region inactivate the E2a gene of adenovirus type 2, 2950 Enkephalin convertase localization by Transcripts of human HLA gene fragments lacking the 5'-terminal region [3Hlguanidinoethylmercaptosuccinic acid autoradiography: Selective in transfected mouse cells (Correction), 3243 association with enkephalin-containing neurons, 6543 Primary structure of the gene encoding rat preprosomatostatin, 3337 Differential processing of prodynorphin and proenkephalin in specific Tandem promoters preceding the gene for the Ml RNA component of regions of thp rat brain, 6886 Escherichia coli P, 3959 Intact proenkephalin is the major enkephalin-containing peptide produced DNA sequence of the carA gene and the control region of carAB: in rat adrenal glands after denervation, 7985 Tandem promoters, respectively controlled by arginine and the , regulate the synthesis of carbamoyl-phosphate synthetase Proenzyme in Escherichia coli K-12, 4134 Cytosolic Ca2+-dependent neutral proteinases from rabbit liver: Multiple regulatory signals in the control region of the Escherichia coli Activation of the proenzymes by Ca2+ and substrate, 53 carAB operon, 4139 Progesterone Individual products of the adenovirus 12S and 13S Ela mRNAs stimulate RU 486: A steroid with antiglucocorticosteroid activity that only and expression at the transcriptional level, 4381 disinhibits the human pituitary-adrenal system at a specific time of viral EIa EIII day, 3879 G + Hereditary persistence of fetal hemoglobi: Cosmid cloning and in the identification of a specific mutation 5' to the y gene, 4894 Calcium-dependent, cyclic nucleotide-independent steroidogenesis An operator at -280 base pairs that is required for repression of araBAD bovine placenta, 6403 operon promoter: Addition of DNA helical turns between the operator Progesterone receptor and promoter cyclically hinders repression, 5017 Progesterone receptor subunits are high-affinity substrates for Human renin gene: Structure and sequence analysis, 5026 phosphorylation by epidermal growth factor receptor, 1654 Defining a bacteriophage T4 late promoter: Bacteriophage T4 gene 55 Molecular cloning of a cDNA for the chicken progesterone receptor B protein suffices for directing late promoter recognition, 5101 antigen, 6358 Generation of deletions in pneumococcal mal genes cloned in Bacillus Proglucagon subtilis, 5189 Conversion of proglucagon in pancreatic alpha cells: The major Distinctive sequence organization and functional programming of an Alu endproducts are glucagon and a single peptide, the major proglucagon repeat promoter, 5291 fragment, that contains two glucagon-like sequences, 5007 Mouse kidney and submaxillary gland renin genes differ in their 5' Prohormone putative regulatory sequences, 5489 Glycine-directed peptide amidation: Presence in rat brain of two enzymes Expression of f-galactosidase controlled by a nitrogenase promoter in that convert p-Glu-His-Pro-Gly-OH into p-Glu-His-Pro-NH2 stem nodules of Aeschynomene scabra, 5806 (thyrotropin-releasing hormone), 3228 Construction of Tn5 lac, a transposon that fuses lacZ expression to Prohormone processing exogenous promoters, and its introduction into Myxococcus Carboxypeptidase B-like converting enzyme activity in secretory granules xanthus, 5816 of rat pituitary, 2776 Isolation of an active transcription initiation complex from HeLa cell-free Proinsulin extract, 5916 Extrapancreatic insulin gene expression in the fetal rat, 3635 Biological Sciences Subject Index Proc. NatL Acad. Sci. USA 81 (1984) 8119

Synthesis of a gene for human growth hormone and its expression in Escherichia coli, 5956 Characterization of a cDNA coding for human protein C, 4766 Proximal and distal domains that control in vitro transcription of the Cloning and sequencing of liver cDNA coding for bovine protein C, 5653 adenovirus IVa2 gene, 6290 Protein conformation Characterization of the Bacillus subtilis tryptophan promoter region, 6315 Predicted secondary structure similarity in the absence of primary amino Antitermination of transcription from an Escherichia coli ribosomal RNA acid sequence homology: Hepatitis B virus open reading frames, 2902 promoter, 6789 Theory of Mdssbauer spectra of proteins fluctuating between Regulation of polyomavirus transcription by large tumor antigen, 6919 conformational substates, 5719 Regulation of ribosomal RNA promoters with a synthetic lac Protein crqladng operator, 6929 F-actin is intermolecularly crosslinked by N,N'-p-phenylenedimaleimide Two regulatory elements for immunoglobulin K light chain gene through lysine-191 and expression, 7041 cysteine-374, 6599 Construction of a retrovirus capable of transducing and expressing genes Protein-deficient diet in multipotential embryonic cells, 7137 Placental lactogen administration reverses the effect of low-protein diet A 1,-base-pair DNA motif that is repeated several times in on maternal and fetal serum somatomedin levels in the pregnant metallothionein gene promoters confers metal regulation to a rat, 5853 heterologous gene, 7318 Protein degradatioi Structural genes of dinitrogenase and dinitrogenase reductase are Effects of temperature on the degradation of proteins in rabbit transcribed from two separate promoters in the broad host range reticulocyte lysates and after injection into HeLa cells, 90 cowpea Rhizobium strain IRc78, 7358 ATP-dependent degradation of ubiquitin-protein conjugates, 1619 Upstream activation sites of the CYCI gene of Saccharotmyces cerevisiae Requirement for alanine in the amino acid control of deprivation4nduced are active when inverted but not when placed downstream of the protein degradation in liver, 4270 "TATA box", 7860 Heat shock regulatory gene htpR influences rates of protein degradation Genetic properties and chromatin structure of the yeast gal regulatory and expression of the lon gene in Escherichia coli, 6647 element: An enhancer-like sequence, 7865 Role of the a-amino group of protein in ubiquitin-mediated protein Promoter PL breakdown, 7021 Exptession of normal and transforming H-ras genes in Escherichia coli Protein dielectric and purification of their encoded p21 proteins, 5305 Macroscopic models for studies of electrostatic interactions in proteins: Promoter PRX Limitations and applicability, 4785 Mutational analysis of a regulatory region in bacteriophage X that has Protein digestion overlapping signals for the initiation of transcription and Pepsin digestibility of proteins in sorghum and other major cereals, 1 translation, 555 Protein-DNA cocrystal Kinetic analysis of mutations affecting the c1I activation site at the P Cocrystals of the DNA-binding domain of phage 434 repressor and a promoter of bacteriophage X, 6432 RE synthetic phage 434 operator, 1307 Prorenin Prbtein-DNA interaction Synthesis of peptides related to the prosegment of mouse submaxillary Detecting protein-DNA interactions in vivo: Distribution of RNA gland renin precursor: An approach to renin inhibitors, 48 polymerase on specific bacterial genes, 4275 Prosomatostatin Protein-DNA re i Characterization of a somatostatin-28 containing the (Tyr-7, Gly-10) Cleavage of the site-specific recombination protein y8 resolvase: The derivative of somatostatin-14: A terminal active product of smaller of two fragments binds DNA specifically, 2001 prosomatostatin II processing in anglerfish pancreatic islets, 7003 Protein dynauies Prostaglandin Picosecond fluorescence decay of tryptophans in myoglobin, 4399 Pleiotropic activities of human interferons are mediated by multiple A consistent picture of protein dynamics, 7088 response pathways, 170 Protein ElA 9-Deoxy_9,A'2-13,14-dihydroprostaglandin D2, a metabolite of Functions of purified ElA protein microinjected into mammalian prostaglandin D2 formed in human plasma, 1317 cells, 6988 Inhibition of tissue damage by the arachidonate lipoxygenase inhibitor Protein engineering BW755C, 2890 Site-specific mutagenesis of the human fibroblast interferon gene, 5662 Prostaglanin D2 Protein evolution Differential sleep-promoting effects of five sleep substances nocturnally Protein differentiation: A comparison of aspartate transcarbamoylase and infused in unrestrained rats, 6240 ornithine transcarbamoylase from Escherichia coli K-12, 4864 P glandin El Intermediate filament cDNAs from BHK-21 cells: Demonstration of Serum-free growth of human mammary epithelial cells: Rapid clonal distinct genes for desmin and vimentin in all vertebrate classes, 5970 growth in defined medium and extended serial passage with pituitary Coagulation factors V and VIII and constitute a family of extract, 5435 structurally related proteins, 6934 Prostate cancer Monoclonal antibodies and peptide mapping reveal structural similarities Simultaneoqs administration of pure antiandrogens, a combination between the subunits of the glycine receptor of rat spinal cord, 7224 necessary for the use of luteinizing hormone-releasing hormone F-Crystallin family of the mouse lens: Structural and evolutionary agonists in the treatment of prostate cancer, 3861 relationships, 7762 Long-acting delivery systems for peptides: Inhibition of rat prostate The molecular clock may be an episodic clock, 8009 tumors by controlled release of [D-Trp6]luteinizing hormone-releasing Protein export hormone from injectable microcapsules, 5845 Protein export in Escherichia coli requires a soluble activity, 7737 Protease Mechanism of toxin secretion by Vibrio cholerae investigated in strains Autodigestion of lexA and phage X repressors, 1375 harboring plasmids that encode heat-labile enterotoxins of Escherichia Biologically active protease of foot and mouth disease virus is expressed coli, 7752 from cloned viral cDNA in Escherichia coli, 3351 Protein factor RF Brain fodrin: Substrate for calpain I, an endogenous calcium-activated Protein synthesis in rabbit reticulocytes: A study of the mechanism of protease, 3572 action of the protein factor RF that reverses protein synthesis inhibition Heat shock regulatory gene htpR influences rates of protein degradation of heme-deficient reticulocyte lysates, 5379 and expression of the Ion gene in Escherichia coli, 6647 Protein flexibility Protease inhibitor Dynamic filtering by two-dimensional 1H NMR with application to phage Protease inhibitors reduce the frequency of spontaneous chromosome X repressor, 6019 abnormalities in cells from patients with Bloom syndrome, 1827 Protein folding Protein 4.1 Proteolysis and the domain organization of myosin subfragment 1, 736 Protein 4.1: Its association with the human erythrocyte membrane, 4404 Single amino acid substitutions influencing the folding pathway of the Protein A phage P22 tail spike endorhamnosidase, 6584 Remission of leukemia and loss of feline leukemia virus in cats injected Kinetic circular dichroism shows that the S-peptide a-helix of with Staphylococcus protein A: Association with increased circulating ribonuclease S unfolds fast and refolds slowly, 7674 interferon and complement-dependgnt cytotoxic antibody, 6471 Protein gp55 Monocytes are required to trigger Ca + uptake in the proliferative Defining a bacteriophage T4 late promoter: Bacteriophage T4 gene 55 response of human T lymphocytes to Staphylococcus aureus protein protein suffices for directing late promoter recognition, 5101 A, 6827 Protein heterogeneity Protein aging Heterogeneity of vertebrate brain tubulins, 4041 Aging of proteins: Isolation and identification of a fluorescent Protein HU chromophore from the reaction of polypeptides with glucose, 2684 Protein HU in the enzymatic replication of the chromosomal origin of Protein, amphipathic Escherichia coli, 424 Rat apolipoprotein A-IV contains 13 tandem repetitions of a 22-amino Protein, hybrid acid segment with amphipathic helical potential, 5021 Envelope proteins of human T-cell leukemia virus: Expression in Protein assembly Escherichia coli and its application to studies of env gene Asymmetric acetylcholinesterase is assembled in the Golgi apparatus, 479 functions, 6202 Involvement of the carboxyl-terminal domain of tubulin in the regulation Protein import of its assembly, 5989 Intracellular targeting and import of an Fl-ATPase /3-subunit-f3- Introductory analysis of the GTP-cap phase-change kinetics at the end of galactosidase hybrid protein into yeast mitochondria, 3983 a microtubule, 6728 Two nuclear mutations that block mitochondrial protein import in Protein, bifunctional yeast, 4819 Internal homologies in the two aspartokipase-homoserine Protein, inframembranous dehydrogenases of Escherichia coli K-12, 3019 Lumen formation and redistribution of inframembranous proteins during differentiation of ducts in the rat mammary gland, 5763 8120 Biological Sciences Subject Index Proc. NatL. Acad. Sci. USA 81 (1984)

Protein interaction Protein phosphorylation A quantitative model for the cooperative mechanism of human Synaptic stimulation alters protein phosphorylation in vivo in a single hemoglobin, 1093 Aplysia neuron, 3233 Protein kinase Protein polymorphism Nucleotide sequence of the feline retroviral oncogene v-fms shows Expandable varl gene of yeast mitochondria DNA: In-frame insertions unexpected homology with oncogenes encoding tyrosine-specific can explain the strain-specific protein size polymorphisms, 3148 protein kinases, 85 Protein processing Regulation of receptor capping in mouse lymphoma T cells by Ca2 - Secretion of foreign proteins from Saccharomyces cerevisiae directed by activated myosin light chain kinase, 165 a-factor gene fusions, 5330 Transformation by polyoma virus is drastically reduced by substitution of Characterization of a somatostatin-28 containing the (Tyr-7, Gly-10) phenylalanine for tyrosine at residue 315 of middle-size tumor derivative of somatostatin-14: A terminal active product of antigen, 679 prosomatostatin II processing in anglerfish pancreatic islets, 7003 The membrane glycoprotein encoded by the retroviral oncogene v-erb-B Molecular cloning and nucleotide sequence of cDNA for rat ornithine is structurally related to tyrosine-specific protein kinases, 704 carbamoyltransferase precursor, 7412 Evidence that the major postsynaptic density protein is a component of a Protein purification Ca2+/calmodulin-dependent protein kinase, 945 Rapid purification of a cloned gene product by genetic fusion and site- Differential cellular distribution of cAMP-dependent protein kinase during specific proteolysis, 4692 development of Dictyostelium discoideum, 2127 Protein secretion Phorbol esters potentiate tyrosine phosphorylation of epidermal growth Determinants for protein localization: P-Lactamase signal sequence factor receptors in A431 membranes by a calcium-independent directs globin across microsomal membranes, 456 mechanism, 2298 Amino acid sequence homology among the major outer membrane Membranes from T and B lymphocytes have different patterns of tyrosine proteins of Escherichia coli, 1048 phosphorylation, 2347 Nucleotide sequence of the Escherichia coli prolipoprotein signal Tumor-promoting phorbol ester stimulates tyrosine phosphorylation in U- peptidase (Isp) gene, 3708 937 monocytes, 2762 Intragenic regions required for LamB export, 3830 Developmental studies of phospholipid-sensitive Ca2'-dependent protein a-Factor-directed synthesis and secretion of mature foreign proteins in kinase and its substrates and of phosphoprotein phosphatases in rat Saccharomyces cerevisiae, 4642 brain, 3143 (Pro)insulin associates with Golgi membranes of pancreatic 13 cells, 6743 Hormonal regulation of hormone-sensitive in intact adipocytes: The 64-kilodalton membrane protein of Bacillus subtilis is also present as Identification of phosphorylated sites and effects on the a multiprotein complex on membrane-free ribosomes, 7772 phosphorylation by lipolytic hormones and insulin, 3317 Protein sequence homology Insulin receptor is an insulin-dependent tyrosine protein kinase: Striking similarities in amino acid sequence among nonstructural proteins Copurification of insulin-binding activity and protein kinase activity to encoded by RNA viruses that have dissimilar genomic homogeneity from human placenta, 3327 organization, 4358 Inhibition by calmodulin of calcium/phospholipid-dependent protein Protein structure phosphorylation, 3622 Location of amino acid alterations in mutants of aspartate New protein kinase from plasma membrane of Ehrlich ascites tumor cells transcarbamoylase: Structural aspects of interallelic activated by natural polypeptides, 4250 complementation, 115 Ca2+/calmodulin-dependent protein kinases from the neuronal nuclear The hydrophobic moment detects periodicity in protein matrix and post-synaptic density are structurally related, 4311 hydrophobicity, 140 Phosphorylation at a tyrosine residue of lipomodulin in mitogen- Amphipathic analysis and possible formation of the ion channel in an stimulated murine thymocytes, 4717 acetylcholine receptor, 155 Immunocytochemical localization of calcium/calmodulin-dependent On the use of sequence homologies to predict protein structure: Identical protein kinase II in rat brain, 5604 pentapeptides can have completely different conformations, 1075 Diacylglycerol stimulates DNA synthesis and cell division in mouse 3T3 The structure of bovine brain myelin proteolipid and its organization in cells: Role of Ca2+-sensitive phospholipid-dependent protein myelin, 2912 kinase, 5748 Structure of unligated aspartate carbamoyltransferase of Escherichia coli Identification of the tyrosine protein kinase from LSTRA cells by use of at 2.6-A resolution, 4037 site-specific antibodies, 6676 Structure of deoxyhemoglobin Cowtown [His HC3(146)p-*Leu]: Origin of High-affinity binding of the regulatory subunit (R ) of cAMP-dependent the alkaline Bohr effect and electrostatic interactions in protein kinase to microtubule-associated and ot'Aer cellular hemoglobin, 4781 proteins, 6723 Macroscopic models for studies of electrostatic interactions in proteins: A protein kinase activity tightly associated with Drosophila type II DNA Limitations and applicability, 4785 topoisomerase, 6938 Stability of "salt bridges" in membrane proteins, 5412 Phosphorylation of the nicotinic acetylcholine receptor by an endogenous The complete cDNA and deduced amino acid sequence of a type II tyrosine-specific protein kinase, 6968 mouse epidermal keratin of 60,000 Da: Analysis of sequence Electrical stimulation increases phosphorylation of tyrosine hydroxylase differences between type I and type II keratins, 5709 in superior cervical ganglion of rat, 7243 Structural stability of the 4-zinc human insulin hexamer, 7093 A placental polypeptide activator of a membranous protein kinase and its Effects of pH on the structure and function of carboxypeptidase A: relation to histone 1, 7388 Crystallographic studies, 7767 Protein kinase C Protein structure, primary Competitive inhibition by diacylglycerol of specific phorbol ester Strategy for the mass spectrometric verification and correction of the binding, 607 primary structures of proteins deduced from their DNA Tumor promoters block tyrosine-specific phosphorylation of the sequences, 1956 epidermal growth factor receptor, 3034 Protein structure, secondary Phorbol 12-myristate 13-acetate, ionomycin or ouabain, and raised Trypanosome variant-specific glycoproteins: A polygene protein family extracellular magnesium induce proliferation of chicken heart with multiple folding patterns?, 998 mesenchymal cells, 6418 Structural model of human ceruloplasmin based on internal triplication, myo-Inositol 1,4,5-trisphosphate stimulates protein phosphorylation in hydrophilic/hydrophobic character, and secondary structure of saponin-permeabilized human platelets, 7431 domains, 4761 Calcium/phospholipid-dependent protein kinase (protein kinase C) Protein differentiation: A comparison of aspartate transcarbamoylase and phosphorylates and activates tyrosine hydroxylase, 7713 ornithine transcarbamoylase from Escherichia coli K-12, 4864 Phorbol esters modulate insulin receptor phosphorylation and insulin Amino acid sequence of bovine heart coupling factor 6, 6603 action in cultured hepatoma cells, 7797 Sequence of the initiation factor IF2 gene: Unusual protein features and Protein localization homologies with elongation factors, 7787 Determinants for protein localization: P3-Lactamase signal sequence Protein subunit interaction directs globin across microsomal membranes, 456 Active-site carbamate formation and reaction-intermediate-analog binding Protein metabolism by ribulosebisphosphate carboxylase/oxygenase in the absence of its Regulation of protein metabolism: Coupling of photosynthetic electron small subunits, 3660 transport to in vivo degradation of the rapidly metabolized 32-kilodalton Order of free energy couplings between ligand binding and protein protein of the chloroplast membranes, 1380 subunit association in hemoglobin, 7098 Protein methylation Protein sulfation Mammalian brain and erythrocyte carboxyl methyltransferases are similar Decrease of tyrosine-O-sulfate-containing proteins found in rat fibroblasts enzymes that recognize both D-aspartyl and L-isoaspartyl residues in infected with Rous sarcoma virus or Fujinami sarcoma virus, 3695 structurally altered protein substrates, 7757 Protein synthesis Protein modification Two initiation sites detected in the small si species of reovirus mRNA by Oxidative inactivation of glutamine synthetase subunits, 2011 dipeptide synthesis in vitro, 1084 Specific protein modifications are altered in a temperature-sensitive Denervated skeletal muscle displays discoordinate regulation for the Drosophila developmental mutant, 6422 synthesis of several myofibrillar proteins, 1122 Protein, nuclear Increased rates of polypeptide chain elongation in placental explants from Isolation of the heterogeneous nuclear RNA-ribonucleoprotein complex human diabetics, 1366 (hnRNP): A unique supramolecular assembly, 7471 Proteins related to the mouse L-cell major heat shock protein are Protein phosphatase synthesized in the absence of heat shock gene expression, 2317 Catalytic site of calmodulin-dependent protein phosphatase from bovine Cellular ADP-ribosyltransferase with the same mechanism of action as brain resides in subunit A, 3054 diphtheria toxin and Pseudomonas toxin A, 2703 Purification and properties of branched-chain a-keto acid dehydrogenase Inhibition of protein synthesis stimulates the transcription of human /8- phosphatase, 4335 interferon genes in Chinese hamster ovary cells, 3964 Cross-linking of tRNA at two different sites of the elongation factor Tu, 3969 Biological Sciences Subject Index Proc. NatL Acad. Sci. USA 81 (1984) 8121

Maturation of catalase precursor proceeds to a different extent in Proton pumping glyoxysomes and leaf peroxisomes of pumpkin cotyledons, 4809 Cooperative transient trapping of photosystem II protons by the integral Epidermal growth factor inhibits the synthesis of the nuclear protein membrane portion (CFO) of chloroplast ATP-synthase after mild cyclin in A431 human carcinoma cells, 4848 extraction of the four-subunit catalytic part (CF1), 3078 Protein synthesis in rabbit reticulocytes: A study of the mechanism of A correlation between proton pumping and the bacteriorhodopsin action of the protein factor RF that reverses protein synthesis inhibition photocycle, 7079 of heme-deficient reticulocyte lysates, 5379 Proton transfer Molecular model of ribosome frameshifting, 5797 Dynamics of enzymatic reactions, 444 In vitro regulation of phage X cII gene expression by Escherichia coli Proton-transfer spectroscopy integration host factor, 6009 Proton-transfer spectroscopy of 3-hydroxyflavone in an isolated-site Distribution of reversing factor in reticulocyte lysates during active crystal matrix, 3375 protein synthesis and on inhibition by heme deprivation or double- Proton transport stranded RNA, 6998 Evidence for rotational contribution to protein-facilitated proton Requirement for protein synthesis in the regulation of a circadian rhythm transport, 1710 by serotonin, 7637 Clathrin-coated vesicles from rat liver: Enzymatic profile and Protein transfer characterization of ATP-dependent proton transport, 3108 Binding of a-bungarotoxin to proteolytic fragments of the a subunit of Protooncogene Torpedo acetylcholine receptor analyzed by protein transfer on Chromosome assignments of four mouse cellular homologs of sarcoma positively charged membrane filters, 2553 and leukemia virus oncogenes, 525 Protein transport Transforming potential of a human protooncogene (c-fps/fes) locus, 3039 Chimeric influenza virus hemagglutinin containing either the NH2 Protoplast terminus or the COOH terminus of G protein of vesicular stomatitis Wound signals in plants: A systemic plant wound signal alters plasma virus is defective in transport to the cell surface, 395 membrane integrity, 3737 In vitro translocation of bacterial proteins across the plasma membrane of Dimethyl sulfoxide can initiate cell divisions of arrested callus protoplasts Escherichia coli, 7421 by promoting cortical microtubule assembly, 5449 Proteinase Lameliar-to-hexogonalil phase transitions in the plasma membrane of Cytosolic Ca2+-dependent neutral proteinases from rabbit liver: isolated protoplasts after freeze-induced dehydration, 6373 Activation of the proenzymes by Ca2+ and substrate, 53 Tumor cell proteinase visualization and quantification using a fluorescent Mn2+ and C2+ toxicity in chlorophyll biosynthesis, 476 transition-state analog probe, 1135 Provlrus Mep-l gene controlling a kidney metalloendopeptidase is linked to the Rearrangement of a DNA sequence homologous to a cell-virus junction major histocompatibility complex in mice, 5542 fragment in several Moloney murine leukemia virus-induced rat A dual role for the Ca2+-requinng proteinase in the degradation of thymomas, 38 hemoglobin by erythrocyte membrane proteinases, 6714 Proviral deletions and oncogene base-substitutions in insertionally Protoycan mutagenized c-myc alleles may contribute to the progression of avian Characterization of -proteoglycan of glomerular basement bursal tumors, 843 membranes, 762 Proviruses are a4jacent to c-myc in some murine leukemia virus-induced Identification of a sulfate-bearing molecule associated with HLA class II lymphomas, 2097 antigens, 1534 Monoclonal integration of human T-cell leukemia provirus in all primary Binding of transferrin to the core protein of fibroblast proteoheparan tumors of adult T-cell leukemia suggests causative role of human T-cell sulfate, 5657 leukemia virus in the disease, 2534 De novo cellular synthesis of sulfated of the developing Proxhty mapping renal glomerulus in vivo, 7108 Application of the Dale-Eisinger analysis to proximity mapping in the Proteoheparan sulfate contractile system, 3723 Binding of transferrin to the core protein of fibroblast proteoheparan Pseudoagoutl phenotype sulfate, 5657 Differential effects of the mottled yellow and pseudoagouti phenotypes on Proteolipid protein immunocompetence in A2pia mice, 2152 Structure and molecular arrangement of proteolipid protein of central Pseudogene nervous system myelin, 5012 Human dihydrofolate reductase gene is located in chromosome 5 and is Proteoliposome unlinked to the related pseudogenes, 1484 Purified reconstituted lac carrier protein from Escherichia coli is fully Are DNA spacers relics of gene amplification events?, 1768 functional, 1629 Evidence for a human histone gene cluster containing H2B and H2A Intramolecular dislocation of the COOH terminus of the lac carrier pseudogenes, 1936 protein in reconstituted proteoliposomes, 4672 Chromosomal organization of the human dihydrofolate reductase genes: Identification and partial purification of the cardiac sodium-calcium Dispersion, selective amplification, and a novel form of exchange protein, 6569 polymorphism, 5170 Proteolysis Rearranged immunoglobulin heavy chain variable region (VH) pseudogene Proteolysis and the domain organization of myosin subfragment 1, 736 that deletes the second complementarity-determining region, 5194 Proteolysis and structure of skeletal muscle actin, 3680 Pseudomonas Rapid purification of a cloned gene product by genetic fusion and site- Major coat protein and single-stranded DNA-binding protein of specific proteolysis, 4692 filamentous virus PS3, 699 Effect of single amino acid replacements on the thermal stability of the Camphor hydroxylase of Pseudomonas putida: Vestiges of sequence NH2-terminal domain of phage X repressor, 5685 homology in cytochrome P450CAM. putidaredoxin, and related Involvement of the carboxyl-terminal domain of tubulin in the regulation proteins, 1664 of its assembly, 5989 Nucleotide sequence surrounding transcription initiation site of xylABC A gene regulating the heat shock response in Escherichia coli also affects operon on TOL plasmid of Pseudomonas putida, 1688 proteolysis, 6779 Cloning, nucleotide sequence, and expression in Escherichia coli of the Schwann cell proliferation and localized proteolysis: Expression of exotoxin A structural gene of Pseudomonas aeruginosa, 2645 plasminogen-activator activity predominates in the proliferating cell Cloned avirulence gene of Pseudomonas syringae pv. glycinea populations, 7216 determines race-specific incompatibility on Glycine max (L.) Proteolytic activation Merr., 6024 Proteolytic activation of a bioactive cardiac peptide by in vitro trypsin Pseudomonas exotoxin A cleavage, 1230 Chromosomal assignment of the gene for human elongation factor 2, 3158 Prothoracicotropic hormone Pseudotype In vitro reprogramming of the photoperiodic clock in an insect brain- Pseudotypes of human T-cell leukemia virus types 1 and 2: Neutralization retrocerebral complex, 5881 by patients' sera, 2886 Prothrombin Pseudion Characterization of a cDNA coding for human factor X, 3699 Chloroplast DNA transcripts are encapsidated by tobacco mosaic virus Prothymosin coat protein, 1719 Prothymosin a: Isolation and properties of the major immunoreactive Psophocarpus form of thymosin a, in rat thymus, 1008 Plasmid-linked ndf and "nod" genes in fast-growing rhizobia that nodulate Distribution of prothymosin a in rat tissues, 1391 Glycine max, Psophocarpus tetragonolobus, and Vigna Distribution of prothymosin a in rat tissues (Correction), 3605 unguiculata, 3093 Proton Pulmonary cyst See also Hydrogen Interferon induces pulmonary cysts in A2G mice, 7937 Proton channel Puisatile s4iling Evidence for the involvement of coupling factor B in the H+ channel of cAMP pulses coordinate morphogenetic movement during fruiting body the mitochondrial H+-ATPase, 1371 formation of Dictyostelium minutum, 2122 Proton electrochemical gradient Pumpkin Functional molecular weight of the lac carrier protein from Escherichia Maturation of catalase precursor proceeds to a different extent in coli as studied by radiation inactivation analysis, 1021 glyoxysomes and leaf peroxisomes of pumpkin cotyledons, 4809 Proton pump Puparium Determination of retinal Schiff base configuration in Hormonal control of eclosion of flies from the puparium, 1457 bacteriorhodopsin, 2055 Purine clash Specific amino acid substitutions in bacterioopsin: Replacement of a Evidence for the existence of stable curvature of DNA in solution, 4632 restriction fragment in the structural gene by synthetic DNA fragments containing altered codons, 2285 8122 Biological Sciences Subject Index Proc. NatL Acad ScL USA 81 (1984)

Purine metabolism R plasmid Assignment of the gene for methylthioadenosine phosphorylase to human Reaction center and light-harvesting I genes from Rhodopseudomonas chromosome 9 by mouse-human somatic cell hybridization, 2665 capsulata, 189 Purine transport Rabbit Photoaffimty labeling and characterization of the cloned purine- Induction of immunoglobulin allotypic suppression in the rabbit: A transport system in Saccharomyces cerevisiae, 6276 cellular approach, 2859 Purineless death Rabies Accumulation of DNA strand breaks and cytotoxicity, 5694 Protection from rabies by a vaccinia virus recombinant containing the Purkinje cell rabies virus glycoprotein gene, 7194 Neuronal influence on glial enzyme expression: Evidence from mutant Rabies virus mouse cerebella, 4414 Inhibition of opiate receptor-mediated signal transmission by rabies virus Purple membrane in persistently infected NG-108-15 mouse neuroblastoma-rat glioma A correlation between proton pumping and the bacteriorhodopsin hybrid cells, 950 photocycle, 7079 Protection from rabies by a vaccinia virus recombinant containing the Putamen rabies virus glycoprotein gene, 7194 Tonically discharging putamen neurons exhibit set-dependent Radial distribution of density responses, 4998 Radial distributions of density within macromolecular complexes Putidaredoin determined from dark-field electron micrographs, 6363 Camphor hydroxylase of Pseudomonas putida: Vestiges of sequence Radiation homology in cytochrome P450CAM' putidaredoxin, and related Mice homozygous for chromosomal deletions in the albino locus region proteins, 1664 lack specific polypeptides in two-dimensional gels, 2132 Putrescine Repeatability of taxon longevity in successive foraminifera radiations and Specificity of polyamine requirements for the replication and maintenance a theory of random appearance and , 5478 of different double-stranded RNA plasmids in Saccharomyces "Hopeful monsters," transposons, and Metazoan radiation, 5482 cerevisiae, 1149 Reduction in the incidence of radiation-induced tumors in rats after pX region restriction of food intake, 7596 Genomes of evolutionarily divergent members of the human T-cell Radiation Inactivation leukemia virus family (HTLV-I and HTLV-II) are highly conserved, Radiation inactivation of oligomeric enzyme systems: Theoretical especially in pX, 4544 considerations, 150 Pyridoxine Functional molecular weight of the lac carrier protein from Escherichia Enzymology of the response of the carpal tunnel syndrome to riboflavin coli as studied by radiation inactivation analysis, 1021 and to combined riboflavin and pyridoxine, 7076 Radiation-induced fibrosarcoma In vivo metabolic effects of hyperglycemia in murine radiation-induced Endonuclease Si-sensitive site in chicken pro-a2(I) collagen 5' flanking fibrosarcoma: A 31P NMR investigation, 6496 gene region, 1659 Radiation leukemia virus DNA sequence of the carA gene and the control region of carAB: Acetylcholine receptor-specific suppressive T-cell factor from a Tandem promoters, respectively controlled by arginine and the retrovirally transformed T-cell line, 7569 pyrimidines, regulate the synthesis of carbamoyl-phosphate synthetase Radical scavenger in Escherichia coli K-12, 4134 Active oxygen acts as a promoter of transformation in mouse embryo Multiple regulatory signals in the control region of the Escherichia coli C3H/1OTVz/C18 fibroblasts, 2085 carAB operon, 4139 Radiodiagnosis Pyrimidine dimer 9"MTc-labeled nucleotides as tumor-seeking radiodiagnostic agents, 918 Escherichia coli DNA photolyase stimulates uvrABC excision nuclease in Radiograph vitro, 7397 Sharpening radiographs, 5237 Pyrimidine nucleotidase Radioimmunoassay Identification of thymidine nucleotidase and deoxyribonucleotidase Hepatitis B viral antigenic structure: Signature analysis by monoclonal activities among normal isozymes of 5'-nucleotidase in human radioimmunoassays, 2237 erythrocytes, 588 Serum a-fetoprotein levels in human disease: Perspective from a highly Pyrimidine-pyrimidone(6-4) product specific monoclonal radioimmunoassay, 3869 Removal of UV light-induced pyrimidine-pyrimidone(6-4) products from Detection of a pancreatic cancer-associated antigen (DU-PAN-2 antigen) Escherichia coli DNA requires the uvrA, uvrB, and urvC gene in serum and ascites of patients with adenocarcinoma, 5242 products, 3821 High-affinity monoclonal antibodies for aflatoxins and their application to Pyrimidine salvage pathway solid-phase immunoassays, 7728 Dipyridamole inhibits reversion by thymidine of methotrexate effect and Radiolabeled antibody increases drug uptake in Sarcoma 180 cells, 3200 Second antibody clearance of radiolabeled antibody in cancer Pyrimidopteridine radioimmunodetection, 2843 Use of riboflavin-binding protein to investigate steric and electronic Radiomimetic drug relationships in flavin analogs and models, 4246 Nitroaromatic radiation sensitizers substitute for oxygen in Pyrogen neocarzinostatin-induced DNA damage, 3312 Specific absorption with monoclonal antibodies to muramyl dipeptide of Radionuclide scintscanning the pyrogenic and somnogenic activities of rabbit monokine, 5888 Imaging of hepatic low density lipoprotein receptors by radionuclide Pyrophosphate scintiscanning in vivo, 7599 Regulation of pea seed pyrophosphate-dependent phosphofructokinase: Radioprotection Evidence for interconversion of two molecular forms as a glycolytic Radioprotection by glutathione ester: Transport of glutathione ester into regulatory mechanism, 5051 human lymphoid cells and fibroblasts, 4732 Pyruvate formate-lyase Ramos lymphoma Post-translational activation introduces a free radical into pyruvate Possible DNA-RNA tumor virus interaction in human lymphomas: formate-lyase, 1332 Expression of retroviral proteins in Ramos lymphoma lines is enhanced Pyruvate kinase after conversion with Epstein-Barr virus, 33 Transitions between oscillatory modes in a glycolytic model system, 4394 Possible DNA-RNA tumor virus interaction in human lymphomas: Pyruvate oxidase Expression of retroviral proteins in Ramos lymphoma lines is enhanced An Escherichia coli mutant deficient in pyruvate oxidase activity due to after conversion with Epstein-Barr virus (Correction), 3918 activation of the enzyme, 4348 Rana altered phospholipid Natural interspecies transfer of mitochondrial DNA in amphibians, 5802 Quadruplet reading Randomness Suppressor sufJ: A novel type of tRNA mutant that induces translational Biological system interactions, 2938 frameshifting, 6105 Rat Quercetin Extrapancreatic insulin gene expression in the fetal rat, 3635 Proton-transfer spectroscopy of 3-hydroxyflavone in an isolated-site Distinct organization of methylcholanthrene- and phenobarbital-inducible crystal matrix, 3375 cytochrome P450 genes in the rat, 5066 Quin-2 Adenosine strongly potentiates pressor responses to nicotine in rats, 5599 Direct demonstration of increased intracellular concentration of free Placental lactogen administration reverses the effect of low-protein diet as measured in stimulated rat mast on maternal and fetal serum somatomedin levels in the pregnant calcium by quin-2 peritoneal rat, 5853 cell, 3978 Isolated uterine nuclei and cytosol receptors of aged rats exhibit impaired Quinazolinone estrogenic stimulation of RNA polymerase II, 7481 Spider sedation induced by defensive chemicals of milliped prey, 806 Reduction in the incidence of radiation-induced tumors in rats after Quinone restriction of food intake, 7596 Mutagenicity of quinones: Pathways of metabolic activation and Molecular cloning and sequence determination of rat preproenkephalin detoxification, 1696 cDNA: Sensitive probe for studying transcriptional changes in rat Membrane protein damage and repair: Selective loss of a quinone-protein tissues, 7651 function in chloroplast membranes, 4070 Rat, Brattieboro Quisqualate Vasopressin gene is expressed at low levels in the hypothalamus of the Selective association of N-methyl aspartate and quisqualate types of L- Brattleboro rat, 5296 glutamate receptor with brain postsynaptic densities, 6876 Rat hepatic lectin Ratiliver receptor lacks a cleavable NH2-terminal signal sequence, 7338 Biological Sciences Subject Index Proc. NatL. Acad. Sci. USA 81 (1984) 8123

Ratchet mechanism Receptors for human y interferon: Binding and crosslinking of 125I_ Molecular model of ribosome frameshifting, 5797 labeled recombinant human y interferon to receptors on WISH Reaction center cells, 5160 Reaction center and light-harvesting I genes from Rhodopseudomonas Receptor-mediated endocytosis of low density lipoprotein: Somatic cell capsulata, 189 mutants define multiple genes required for expression of surface- Structural studies of the primary donor cation radical P"0 in reaction receptor activity, 5454 centers of Rhodospirillum rubrum by electron-nuclear double Receptors for human a and /3 interferon but not for y interferon are resonance in solution, 1401 specified by human chromosome 21, 5504 Crystallization of reaction center from Rhodopseudomonas sphaeroides: Specific membrane receptors for atrial natriuretic factor in renal and Preliminary characterization, 4795 vascular tissues, 5946 Primary structure of the L subunit of the reaction center from Extention of bacteriophage X host range: Selection, cloning, and Rhodopseudomonas sphaeroides, 7303 characterization of a constitutive X receptor gene, 6080 N electron nuclear double resonance of the primary donor cation radical Thyrotropin-releasing hormone stimulates GTP hydrolysis by membranes P" in reaction centers of Rhodopseudomonas sphaeroides: Additional from GH4C1 rat pituitary tumor cells, 6183 evidence for the dimer model, 7792 Molecular cloning of a cDNA for the chicken progesterone receptor B recA protein antigen, 6358 Mechanism of the concerted action of recA protein and helix-destabilizing Purification and chemical characterization of the receptor for interleukin proteins in homologous recombination, 2757 2 from activated human T lymphocytes and from a human T-cell Isolation and visualization of active presynaptic filaments of recA protein lymphoma cell line, 6481 and single-stranded DNA, 7026 Stimulatory GTP regulatory unit N5 and the catalytic unit of adenylate Involvement of the activated form of RecA protein in SOS mutagenesis cyclase are tightly associated: Mechanistic consequences, 6579 and stable DNA replication in Escherichia coli, 7539 Transcriptional induction of two genes in human cells by /3 interferon, 6733 Receptor Selective association of N-methyl aspartate and quisqualate types of L- See also specific compounds glutamate receptor with brain postsynaptic densities, 6876 Amphipathic analysis and possible formation of the ion channel in an Purification of the muscarinic acetylcholine receptor from porcine atria acetylcholine receptor, 155 (Correction), 7258 Morphologic characterization of the pathway of transferrin endocytosis Analysis of the insulin receptor by anti-receptor antibodies and flow and recycling in human KB cells, 175 cytometry, 7446 Receptor-mediated activation of a phospholipase A2 in rabbit neutrophil Blockade of autocrine stimulation in simian sarcoma virus-transformed plasma membrane, 767 cells reverses down-regulation of platelet-derived growth factor Identification of a 145,000 M. membrane protein as the C3d receptor receptors, 7466 (CR2) of human B lymphocytes, 881 Specific binding of erythropoietin to spleen cells infected with the A glioma-derived analog to platelet-derived growth factor: Demonstration strain of Friend virus, 7574 of receptor competing activity and immunological crossreactivity, 926 Synthesis in animal cells of hepatitis B surface antigen particles carrying Biologically active synthetic fragments of epidermal growth factor: a human serum Localization of a major receptor-binding region, 1351 receptor for polymerized albumin, 7708 Triggering of the T3-Ti antigen-receptor complex results in clonal T-cell Receptor alosterism proliferation through an interleukin 2-dependent autocrine Multiple opioid receptors in endotoxic shock: Evidence for a involvement pathway, 1509 and A- interactions in vivo, 2898 Isolation and partial characterization of concanavalin A receptors on Receptor binding cloned cytotoxic T lymphocytes, 1519 Micromolar-affinity benzodiazepine receptors regulate voltage-sensitive Messenger RNA for an antigen-specific binding molecule from an antigen- calcium channels in nerve terminal preparations, 3118 specific T-cell hybrid, 1524 Receptor capping Autoradiographic localization of angiotensin II receptors in rat Regulation of receptor capping in mouse lymphoma T cells by Ca2+- brain, 1575 activated myosin light chain kinase, 165 Quantitative autoradiography of Pi- and f2-adrenergic receptors in rat Receptor cell brain, 1585 Specific olfactory receptor populations projecting to identified glomeruli Monoclonal antibodies against the rat liver glucocorticoid receptor, 1609 in the rat olfactory bulb, 5250 Progesterone receptor subunits are high-affinity substrates for Receptor clustering phosphorylation by epidermal growth factor receptor, 1654 Transformation by Rous sarcoma virus prevents acetylcholine receptor Isolation of an angiotensin II-binding protein from liver, 1679 clustering on cultured chicken muscle fibers, 2265 Time-resolved photolabeling by the noncompetitive blocker Receptor cycling chlorpromazine of the acetylcholine receptor in its transiently open and closed ion channel conformations, 1897 Rapid internalization of the transferrin receptor in K562 cells is triggered Antigenic stimulation regulates the level of expression of interleukin 2 by ligand binding or treatment with a phorbol ester, 3005 receptor on human T cells, 2172 Receptor degradation Increase in the Bmax of y-aminobutyric acid-A recognition sites in brain Down-regulation of the epidermal growth factor receptor in KB cells is regions of mice receiving diazepam, 2247 due to receptor internalization and subsequent degradation in Multiple opiate receptors in the guinea pig enteric nervous system: lysosomes, 2384 Unmasking the copresence of receptor subtypes, 2252 Receptor evolution Interaction of the la,25-dihydroxyvitamin D3 receptor with RNA and Monoclonal antibodies detect the conservation of muscarinic cholinergic synthetic polyribonucleotides, 2337 receptor structure from Drosophila to human brain and detect possible Antibody against the insulin receptor causes disappearance of insulin structural homology with a1-adrenergic receptors, 272 receptors in 3T3-L1 cells: A possible explanation of antibody-induced Receptor internalization insulin resistance, 2508 Down-regulation of the epidermal growth factor receptor in KB cells is Assignment of the human gene for the low density lipoprotein receptor to due to receptor internalization and subsequent degradation in chromosome 19: Synteny of a receptor, a ligand, and a genetic lysosomes, 2384 disease, 2826 Receptor kinase Plasma binding proteins for platelet-derived growth factor that inhibit its Antibodies to two defined regions of the transforming protein pp6Osrc binding to cell-surface receptors, 3424 interact specifically with the epidermal growth factor receptor kinase Binding of the differentiation-inducer, granulocyte-colony-stimulating system, 5911 factor, to responsive but not unresponsive leukemic cell lines, 3765 Calmodulin-stimulated phosphorylation of 17,8-estradiol receptor on Purification and NH2-terminal amino acid sequencing of the v subunit of tyrosine, 5921 a human T-cell antigen receptor, 3851 Receptor-ligand interaction Insulin activates the appearance of insulin-like growth factor II receptors The increase in intracellular free calcium associated with IgGy2b/-yl Fc on the adipocyte cell surface, 4028 receptor-ligand interactions: Role in phagocytosis, 5430 Solubilization and characterization of A, 6, and K opioid binding sites The increase in intracellular free calcium associated with IgGy2b/yl Fc from guinea pig brain: Physical separation of K receptors, 4217 receptor-ligand interactions: Role in phagocytosis (Correction), 7258 Solubilization and characterization of thyrotropin-releasing hormone Receptor regulation receptors from rat brain, 4227 Decreased physiological sensitivity mediated by newly synthesized Epstein-Barr virus receptor of human B lymphocytes is the C3d receptor muscarinic acetylcholine receptors in embryonic chicken heart, 3582 CR2, 4510 Receptor transduction Modulation of human lymphocyte responses by low density lipoproteins Pharmacomechanical coupling in smooth muscle may involve (LDL): Enhancement but not immunosuppression is mediated by LDL 6899 receptors, 4539 phosphatidylinositol metabolism, Parkinsonism-inducing neurotoxin, N-methyl-4-phenyl-1,2,3,6- Receptosome tetrahydropyridine: Characterization and localization of receptor Down-regulation of the epidermal growth factor receptor in KB cells is binding sites in rat and human brain, 4591 due to receptor internalization and subsequent degradation in Influence of the 3-adrenergic receptor concentration on functional lysosomes, 2384 coupling to the adenylate cyclase system, 4637 Recognition Spatial relationships of the human chorionic gonadotropin (hCG) subunits Understanding biological computation: Reliable learning and in the assembly of the hCG-receptor complex in the luteinized rat recognition, 6871 ovary, 4667 Recombinant DNA ADP-dependent common receptor mechanism for binding of von High-level production of biologically active human a1-antitrypsin in Willebrand factor and fibrinogen to human platelets, 4935 Escherichia coli, 669 Purification of the muscarinic acetylcholine receptor from porcine Cloning and expression of human erythropoietin cDNA in Escherichia atria, 4993 coli, 2708 Binding of [3Hlforskolin to rat brain membranes, 5081 Rapid purification of a cloned gene product by genetic fusion and site- specific proteolysis, 4692 8124 Biological Sciences Subject Index Proc. Natl. Acad. Sci. USA 81 (1984)

Secretion of human parathyroid hormone from rat pituitary cells infected Mouse kidney and submaxillary gland renin genes differ in their 5' with a recombinant retrovirus encoding preproparathyroid putative regulatory sequences, 5489 hormone, 5340 Renin gene Recombination Structure of the human renin gene, 5999 A pattern of partially homologous recombination in mouse L cells, 206 Reovirus Interaction of the bacteriophage P1 recombinase Cre with the Two initiation sites detected in the small si species of reovirus mRNA by recombining site loxP, 1026 dipeptide synthesis in vitro, 1084 Chloroplast DNA recombination in interspecific hybrids of Replication Chlamydomonas: Linkage between a nonmendelian locus for Replication of the broad host range plasmid RSF1010: Requirement for streptomycin resistance and restriction fragments coding for 16S three plasmid-encoded proteins, 654 rRNA, 1164 Specificity of polyamine requirements for the replication and maintenance Mechanism of the concerted action of recA protein and helix-destabilizing of different double-stranded RNA plasmids in Saccharomyces proteins in homologous recombination, 2757 cerevisiae, 1149 Stimulation of recombination between homologous sequences on plasmid Characterization and purification of a phage 429-encoded DNA DNA and chromosomal DNA in Escherichia coli by N-acetoxy-2- polymerase required for the initiation of replication, 5325 acetylaminofluorene, 2831 Plasmid P1 replication: Negative control by repeated DNA Homologous recombination between plasmids in mammalian cells can be sequences, 6456 enhanced by treatment of input DNA, 3153 Yeast mitochondrial genomes consisting of only A-T base pairs replicate Strategies for multilocus linkage analysis in humans, 3443 and exhibit suppressiveness, 7156 Recombination of transfected in vertebrate cells in culture, 3476 Evidence for inclusion of regions of nonhomology in heteroduplex Selective isolation of cosmid clones by homologous recombination in products of bacteriophage X recombination, 7180 Escherichia coli, 4129 Molecular analysis of the recF gene of Escherichia coli, 4622 Replication-defective mutant recA-independent recombination of y8 termini and at IS3 producing Escherichia coli mutants suppressing replication-defective mutations of inverted repetition in F' plasmids, 4869 the ColEl plasmid, 550 Hyperrecombination at a specific DNA sequence in pneumococcal Escherichia coli mutants suppressing replication-defective mutations of transformation, 5184 the ColEl plasmid (Correction), 2944 Genetic recombination can generate altered restriction specificity, 6095 Replication fork Spontaneous deletions and duplications of sequences in the genome of Mammalian DNA polymerase a holoenzymes with possible functions at cowpox virus, 6817 the leading and lagging strand of the replication fork, 3993 Isolation and visualization of active presynaptic filaments of recA protein Repression and single-stranded DNA, 7026 An operator at -280 base pairs that is required for repression of araBAD Evidence for inclusion of regions of nonhomology in heteroduplex operon promoter: Addition of DNA helical turns between the operator products of bacteriophage X recombination, 7180 and promoter cyclically hinders repression, 5017 Enhanced recombination between Xplac5 and F42lac: Identification of Repression, topological cis- and trans-acting factors, 7500 Topological repression of gene activity by a transposable element, 6115 Simian virus 40 T antigen is required for viral excision from Repressor chromosomes, 7534 Use of the Escherichia coli lac repressor and operator to control gene A new class of Escherichia coli recBC mutants: Implications for the role expression in Bacillus subtilis, 439 of RecBC enzyme in homologous recombination, 7850 Molecular analysis of the Neurospora qa-l regulatory region indicates Cytological mapping of the human glucose-6-phosphate dehydrogenase that two interacting genes control qa gene expression, 1174 gene distal to the fragile-X site suggests a high rate of meiotic Cocrystals of the DNA-binding domain of phage 434 repressor and a recombination across this site, 7855 synthetic phage 434 operator, 1307 Identification of a recent recombination event within the human ,3-globin Autodigestion of lexA and phage X repressors, 1375 gene cluster, 7875 DNA sequences of the repressor gene and operator region of Recombination, illegitimate bacteriophage P2, 3988 Illegitimate recombination generates a class switch from to C,; in an Effect of single amino acid replacements on the thermal stability of the IgD-secreting plasmacytoma, 4164 CA NH2-terminal domain of phage A repressor, 5685 Recombination protein Dynamic filtering by two-dimensional H NMR with application to phage Cleavage of the site-specific recombination protein y8 resolvase: The X repressor, 6019 smaller of two fragments binds DNA specifically, 2001 Demonstration of two operator elements in gal: In vitro repressor binding Rectifier, delayed outward studies, 6100 Development of a delayed outward-rectifying K+ conductance in cultured Reproduction mouse peritoneal macrophages, 3083 Eutherian-like reproductive specializations in a viviparous reptile, 4860 Redox component Reproductive isolation Relationship between lateral diffusion, collision frequency, and electron Genetic basis of male sterility in hybrids between two closely related transfer of mitochondrial inner membrane oxidation-reduction species of Drosophila, 4444 components, 2606 Reptile Reductase kinase Eutherian-like reproductive specializations in a viviparous reptile, 4860 In vivo modulation of rat liver 3-hydroxy-3-methylglutaryl-coenzyme A Repulsive force reductase, reductase kinase, and reductase kinase kinase by Measurement of the repulsive force between polyelectrolyte molecules in mevalonolactone, 7293 ionic solution: Hydration forces between parallel DNA double Reductase kinase kinase helices, 2621 In vivo modulation of rat liver 3-hydroxy-3-methylglutaryl-coenzyme A Reserpine reductase, reductase kinase, and reductase kinase kinase by Alternative modes of enkephalin biosynthesis regulation by reserpine and mevalonolactone, 7293 cyclic AMP in cultured chromaffin cells, 3949 Refractoriness Resonance Raman spectroscopy Simple finite-element model accounts for wide range of cardiac Iron-carbon bond lengths in carbonmonoxy and cyanomet complexes of dysrhythmias, 233 the monomeric hemoglobin III from Chironomus thummi thummi: A Regeneration critical comparison between resonance Raman and x-ray diffraction Substances originating from the optic nerve of neonatal rabbit induce studies, 5106 regeneration-associated response in the injured optic nerve of adult Respiratory syncytial virus rabbit, 7965 Nucleotide sequence of the gene encoding the fusion (F) glycoprotein of Regioselectivity human respiratory syncytial virus, 7683 Regioselective arylation of ribose in adenosine and guanosine with the Restriction element antitumor drug N2-methyl-9-hydroxyellipticinium acetate, 1297 Antigen presentation by murine and human cells to a murine T-cell Regulator hypothesis hybridoma: Demonstration of a restriction element associated with a Cell adhesion and morphogenesis: The regulator hypothesis, 1460 major histocompatibility complex class II determinant(s) shared by Regulatory gene both species, 7559 Rapid mutational analysis of regulatory loci in Escherichia coli K-12 using Restriction endonuclease bacteriophage M13, 3801 Restriction can be used to study B-Z junctions in Locus unlinked to a-fetoprotein under the control of the murine raf and supercoiled DNA, 5714 Rif genes, 5523 Genetic recombination can generate altered restriction specificity, 6095 Regulatory sequence Restriction endonuclease Dpn I Evidence for a human histone gene cluster containing H2B and H2A Site-specific cleavage of DNA at 8- and 10-base-pair sequences, 983 pseudogenes, 1936 Restriction endonuclease Hha I Reiterated DNA In Z-DNA the sequence G-C-G-C is neither methylated by Hha I Molecular hybridization under conditions of high stringency permits methyltransferase nor cleaved by Hha I restriction endonuclease, 3268 cloned DNA segments containing reiterated DNA sequences to be Restriction endonuclease site polymorphism assigned to specific chromosomal locations, 520 Regional localization on the human X chromosome and polymorphism of Relayed correlation spectroscopy the coagulation factor IX gene (hemophilia B locus), 498 Multiple-step relayed correlation spectroscopy: Sequential resonance Origin of the (3 -globin gene in Blacks: The contribution of recurrent assignments in oligosaccharides, 6286 mutation or gene conversion or both, 853 Renin P3-Thalassemia in American Blacks: Novel mutations in the "TATA" box Synthesis of peptides related to the prosegment of mouse submaxillary and an acceptor splice site, 1154 gland renin precursor: An approach to renin inhibitors, 48 Evidence for the multicentric origin of the sickle cell hemoglobin gene in Human renin gene: Structure and sequence analysis, 5026 Africa, 1771 Biological Sciences Subject Index Proc. NatL. Acad. Sci USA 81 (1984) 8125

Class II HLA-DC 13-chain DNA restriction fragments differentiate among Nucleotide sequence of the feline retroviral oncogene v-fms shows HLA-DR2 individuals in insulin-dependent diabetes and multiple unexpected homology with oncogenes encoding tyrosine-specific sclerosis, 1774 protein kinases, 85 DNA polymorphic loci mapped by human chromosomes 3, 5, 9, 11, 17, Frequent generation of nonrescuable reorganized Moloney murine 18, and 22, 2447 sarcoma viral genomes, 294 Segregation patterns of polymorphic restriction sites of the gene encoding Amounts, synthesis, and some properties of intracisternal A particle- the a subunit of human chorionic gonadotropin in trophoblastic related RNA in early mouse embryos, 488 disease, 2504 The membrane glycoprotein encoded by the retroviral oncogene v-erb-B 1-Thalassemia in Chinese: Use of in vivo RNA analysis and is structurally related to tyrosine-specific protein kinases, 704 oligonucleotide hybridization in systematic characterization of Molecular cloning of a unique human T-cell leukemia virus (HTLV- molecular defects, 2821 RIMo), 993 Genetic mapping of the human X chromosome by using restriction Nucleotide sequence analysis of the long terminal repeat of human T-cell fragment length polymorphisms, 2836 leukemia virus type II, 1079 Strategies for multilocus linkage analysis in humans, 3443 Insertion of retrovirus into the first intron of al(I) collagen gene leads to Six HLA-D region a-chain genes on human chromosome 6: embryonic lethal mutation in mice, 1504 Polymorphisms and associations of DCa-related sequences with DR Hematopoietic cell transformation by a murine recombinant retrovirus types, 3461 containing the src gene of Rous sarcoma virus, 2374 Linkage disequilibrium and evolutionary relationships of DNA variants Nucleotide-sequence of avian carcinoma virus MH2: Two potential onc (restriction enzyme fragment length polymorphisms) at the serum genes, one related to avian virus MC29 and the other related to murine albumin locus, 3486 sarcoma virus 3611, 3000 13-Thalassemia in American Blacks: Novel mutations in the "TATA" box Recombination of transfected DNAs in vertebrate cells in culture, 3476 and an acceptor splice site (Correction), 3605 Decrease of tyrosine-O-sulfate-containing proteins found in rat fibroblasts Molecular organization of the HLA-SB region of the human major infected with Rous sarcoma virus or Fujinami sarcoma virus, 3695 histocompatibility complex and evidence for two SB 13-chain Possible DNA-RNA tumor virus interaction in human lymphomas: genes, 3934 Expression of retroviral proteins in Ramos lymphoma lines is enhanced Structural gene for 13-nerve growth factor not defective in familial after conversion with Epstein-Barr virus (Correction), 3918 dysautonomia, 4213 Properties of retrovirus-like particles produced by a human breast No evidence for differences in the Epstein-Barr virus genome carried in carcinoma cell line: Immunological relationship with mouse mammary Burkitt lymphoma cells and nonmalignant lymphoblastoid cells from tumor virus proteins, 4188 the same patients, 4930 Genomes of evolutionarily divergent members of the human T-cell Clones from the human gene complex coding for salivary proline-rich leukemia virus family (HTLV-I and HTLV-II) are highly conserved, proteins, 5561 especially in pX, 4544 Patterns of polymorphism and linkage disequilibrium suggest independent Repetitive structure in the long-terminal-repeat element of a type II origins of the human growth hormone gene cluster, 6085 human T-cell leukemia virus, 4617 Polymorphisms of a human variable heavy chain gene show linkage with Bovine leukemia virus: Unique structural features of its long terminal constant heavy chain genes, 7840 repeats and its evolutionary relationship to human T-cell leukemia Identification of a recent recombination event within the human 1-globin virus, 4741 gene cluster, 7875 Secretion of human parathyroid hormone from rat pituitary cells infected Ribosomal DNA spacer-length polymorphisms in barley: Mendelian with a recombinant retrovirus encoding preproparathyroid inheritance, chromosomal location, and population dynamics, 8014 hormone, 5340 Restriction fragment High-efficiency gene transfer into mammalian cells: Generation of helper- Clusters of HLA class 11P3 restriction fragments describe allelic free recombinant retrovirus with broad mammalian host range, 6349 series, 7870 A mutant murine leukemia virus with a single missense codon in pol is defective in a function affecting integration, 6461 Restriction fragment length polymorphism Detection and immunochemical characterization of a primate type C See Restriction endonuclease site polymorphism retrovirus-related p30 protein in normal human placentas, 6501 Restriction methylase Integration-specific retrovirus expression in embryonal carcinoma Site-specific cleavage of DNA at 8- and 10-base-pair sequences, 983 cells, 6627 Reticular complex Nucleotide sequence of the 3' region of an infectious human T-cell Function of the thalamic reticular complex: The searchlight leukemia virus type II genome, 6657 hypothesis, 4586 Genomic structure and possible retroviral origin of the chicken CR) Reticulocyte repetitive DNA sequence family, 6667 Protein synthesis in rabbit reticulocytes: A study of the mechanism of Evidence that a major class of mouse endogenous long terminal repeats action of the protein factor RF that reverses protein synthesis inhibition (LTRs) resulted from recombination between exogenous retroviral of heme-deficient reticulocyte lysates, 5379 LTRs and similar LTR-like elements (LTR-IS), 66% Reticulocyte lysate Viral integration near c-myc in 10-20o of MCF 247-induced AKR Effects of temperature on the degradation of proteins in rabbit lymphomas, 6808 reticulocyte lysates and after injection into HeLa cells, 90 Construction of a retrovirus capable of transducing and expressing genes Retina in multipotential embryonic cells, 7137 Sensitive light scattering probe of enzymatic processes in retinal rod Introduction of a selectable gene into different animal tissue by a photoreceptor membranes, 743 retrovirus recombinant vector, 7151 The goldfish nervus terminalis: A luteinizing hormone-releasing hormone Retrovirus-induced expression of interleukin 2 receptors on cells of and molluscan cardioexcitatory peptide immunoreactive olfactoretinal human B-cell lineage, 7441 pathway, 940 Identification of a retrovirus-like repetitive element in human DNA, 7510 Identification of novel neural- and neural retina-specific antigens with a The retrovirus pol gene encodes a product required for DNA integration: monoclonal antibody, 2260 Identification of a retrovirus int locus, 7885 Activity and the control of ganglion cell death in the rat retina, 5589 Retrovirus vector Monoclonal antibodies distinguish subtypes of retinal horizontal Cell-specified expression of a selectable hybrid gene, 4657 cells, 6255 Reversing factor y-Aminobutyric acid acts at axon terminals of turtle photoreceptors: Distribution of reversing factor in reticulocyte lysates during active Difference in sensitivity among cell types, 7961 protein synthesis and on inhibition by heme deprivation or double- Retinal stranded RNA, 6998 Dark-adapted bacteriorhodopsin contains 13-cis,15-syn and all-trans,15- Reward anti retinal Schiff bases, 1706 Changes in local cerebral glucose utilization during rewarding brain Determination of retinal Schiff base configuration in stimulation, 635 bacteriorhodopsin, 2055 Reye syndrome Retinal migration during dark reduction of bacteriorhodopsin, 2303 Dose-related effect of acetylsalicylic acid on replication of varicella zoster Fluorescence quantum yield of visual pigments: Evidence for virus in vitro, 5223 subpicosecond isomerization rates, 4790 Development of encephalopathic features similar to Reye syndrome in Retinoic acid rabbits, 6169 Induction of murine teratocarcinoma cell differentiation by suppression of Rhesus antigen poly(ADP-ribose) synthesis, 7132 Production of human monoclonal IgG antibodies against Rhesus (D) Retinol antigen, 3214 Carotenoids and retinol: Their possible importance in determining Rhesus monkey longevity of primate species, 7627 Birth of rhesus monkey infant after in vitro fertilization and nonsurgical Retinotectal map embryo transfer, 2218 Alteration of the retinotectal map in Xenopus by antibodies to neural cell Rheumatic fever adhesion molecules, 4222 Epitope-specific protective immunogenicity of chemically synthesized Retinotectal projection 13-, 18-, and 23-residue peptide fragments of streptococcal M Fiber-fiber interaction and tectal cues influence the development of the protein, 2203 chicken retinotectal projection, 1906 Rheumatoid factor Retraction Anti-hypervariable region antibody induced by a defined peptide: An A precise termination site in the mouse 3majir-globin transcription approach for studying the structural correlates of idiotypes, 1784 unit, 2274 Rhiwob"u Retrovirus Rhizobium free-living nitrogen fixation occurs in specialized nongrowing Possible DNA-RNA tumor virus interaction in human lymphomas: cells, 1566 Expression of retroviral proteins in Ramos lymphoma lines is enhanced Plasmid-linked nif and "nod" genes in fast-growing rhizobia that nodulate after conversion with Epstein-Barr virus, 33 Glycine max, Psophocarpus tetragonolobus, and Vigna unguiculata, 3093 8126 Biological Sciences Subject Index Proc. NatL Acad. Sc4 USA 81 (1984)

Expression of /B-galactosidase controlled by a nitrogenase promoter in Chloroplast DNA recombination in interspecific hybrids of stem nodules of Aeschynomene scabra, 5806 Chlamydomonas: Linkage between a nonmendelian locus for Structural genes of dinitrogenase and dinitrogenase reductase are streptomycin resistance and restriction fragments coding for 16S transcribed from two separate promoters in the broad host range rRNA, 1164 cowpea Rhizobium strain IRc78, 7358 Are DNA spacers relics of gene amplificatiod events?, 1768 Rhodopseudomonas Identification of a site on 23S ribosomal RNA Ibcated at the peptidyl Reaction center and light-harvesting I genes from Rhodopseudomonas transferase center, 3607 capsulata, 189 Antitermination of transcription from an Escherichia coli ribosomal RNA Crystallization of reaction center from Rhodopseudomonas sphaeroides: promoter, 6789 Preliminary characterization, 4795 Regulation of ribospmal RNA promoters with a synthetic lac Triazine herbicide resistance in the photosynthetic bacterium operator, 6929 Rhodopseudomonas sphaeroides, 6310 Ribosomal RNA gene Primary structure of the L subunit of the reaction center from Determination of the promoter regioh of mouse ribosomal RNA gene by Rhodopseudomonas sphaeroides, 7303 an in vitro transcription system, 299 "N electron nuclear double resonance of the primary donor cation radical Pronounced structural similarities between the small subunit ribosomal P" in reaction centers of Rhodopseudomonas sphaeroides: Additional RNA genes of wheat mitochondria and Escherichia coli, 493 evidence for the dimer model, 7792 Quantitation of aflatoxin B1 adduction within the ribosomal RNA gene Rhodopsin sequences of rat liver DNA, 664' Sensitive light scattering probe of enzymatic processes in retinal rod Localization of RNA polymerpse I in interphase cells and mitotic photoreceptor membranes, 743 chromosomes by light and electron microscopic Fluorescence quantum yield of visual pigments: Evidence for immunocytochemistry, 1431 subpicosecond isomerization rates, 4790 Determination of the promoter region of mouse ribosomal RNA gene by Isolation and nurleotide sequence of the gene encoding human an in vitro transcqption system (Correction), 2587 rhodopsin, 4851 A purified fraction cbntaining RNA polymerase I that can accurately Squid rhodopsin and GTP-biqding protein crossreact with vertebrate transcribe rat uibosomal RNA gene, 6612 photoreceptor enzymes, 5111 Ribome Reconstitution of purified halorhodopsin, 5408 RNase III cleavage is obligate for maturation but not for function of RhodospirWum Escherichia coli pre-23S rRNA, 185 Structural studies of the primary donor cation radical P" in reaction Eocytes: A new ribpsome structure indicates a kingdom with a close centers of Rhodospirillum rubrum by electron-nuclear double relationship to eukaryotes, 3786 resonance in solution, 1401 Molecular model of ribosome frameshiAiqg, 5797 Riboflavin Escherichia co/i translational initiation factor IF3: A unique case of Enzymology of the response of the carpal tunnel syndrome to riboflavin translational regulation, 7061 and to combined riboflavin and pyridoxine, 7076 The 64-kilodalton membrane protein of Bacillus subtilis is also present as Riboflavin-binding protein a multiprotein complex on membrane-free ribosomes, 7772 Use of riboflavin-binding protein to investigate steric and electronic Ribosome transit time relationships in flavin analogs and models, 4246 Increased rates of polypeptide chain elongation in placental explants from Ribonuclease human diabetics, 1366 RNase III cleavage is obligate for maturation but not for function of Ribulose-1,5-bisphosphate carboxylase Escherichia coli pre-23S rRNA, 185 Demonstration of transcriptional regulation of specific genes by Nuclease protection analysis of ribonucleoprotein complexes: Use of the phytochrome action, 1112 cytotoxic ribonuclease a-sarcin to determine the binding sites for Active-site carbamate formation and reaction-intermediate-analog binding Escherichia coli ribosomal proteins L5, L1, and L25 on 5S rRNA, 322 by ribulosebisphosphate carboxylase/oxygenase in the absence of its RNase H confers specificity in the dnaA-dependent initiation of small subunits, 3660 replication at the unique origin of the Escherichia cqli chromosome in Single gene for the large subunit of ribulosebisphqpphate carboxylase in vivo and in vitro, 1040 maize yields two differentially regulated mRN,4s, 4060 The rnh gene is essential for growth of Escherichia coli, 3447 Cotranscription of genes encoding the small b0 large subunits of Kinetic circular dichroism shows that the S-peptide a-helix of ribulose-1,5-bisphosphate carboxylase in 'the cyanobacterium Anabaena ribonuclease S unfolds fast and refolds slowly, 7674 7120, 5961 The absence of RNase H allqws replication of pBR322 in Escherichia coli Rimorphin mutants lacking DNA polymerase I, 7845 Dynorphin converting enzyrpe with unusual specificity from rat brain, 1892 Tandem promoters preceding the gene for the Ml RNA component of Ring gland Escherichia coli ribonuclease J, 3959 Evidence for the presence of magisterone A in Drosophila larvae and the Ribonudease T secretion of 20-deoxymaklisterone A by the ring gland, 5643 Ribonuclease T: New possibly involved in end-turnover RNA of tRNA, 4290 Amounts, synthesis, and some properties of intfacisternal A particle- Ribonudeoprotein related RNA in early mouse embryos, 488 Nuclease protection analysis pf ribonucleoprotein complexes: Use of the Interaction of the la,25-dihydroxyvitamin D3 receptor with RNA and cytotoxic ribonuclease a-sarcin to determine the binding sites for synthetic polyribonucleotides, 2337 Escherichia coli ribosomal proteins L5, L18, and L25 on 5S rRNA, 322 Nature and origin of the RNA associated with simian virus 40 large tumor The Ro small cytoplasmic ribonucleoproteins: Identification of the antigen, 5425 antigenic protein and its binding si e on the Ro RNAs, 1996 An 8-kilobase abl RNA transcript in chronic myelogenous leukemia, 5648 Ribonudleoside diphosphate reductase U1 RNA-protein complex preferentially binds to both 5' and 3' splice Primary structure of the Escherichia coli ribonucleoside diphosphate junction sequences idi RNA or single-stranded DNA, 6281 reductase operon, 4294 Characterization of epidermal growth factor receptor gene expression in Ribose malignant and normal human cell lines, 7308 Regioselective arylation of ribose in adenosine and guanosine with the RNA chain elongation antitumor drug N2-methyl-9-hydroxyellipticinium acetate, 1297 Purification of cowpea mojaic virus RNA replication complex: Identificatin °of a virus-encoded 110,000-dalton polypeptide responsible Ribosomal DNA for Differentiation of schistosomes by species, strain, and sex by using INA chaip elongation, 1951 cloned DNA markers, 889 RNA, complqmeptary Ribosomal DNA spacer-length polymorphisms in barley: Mendelian Anti-mniVA: Specific inhijitiop of translation of single mRNA inheritance, chromosomal location, and population dynamics, 8014 molecules,. 7525 Ribosomal gene RNA, double-stranded On the mechanism of nucleolar dominance in mouse-human somatic cell Specifieity of polyamine requirements for the replication and maintenance 484 of different double-strandqd RNA plasmids in Saccharqmyces hybrids, cerevisiae, 1149 Ribosomal promoter element Inhibition of protein synthesis stimulates the transcription of human /3- In vitro mutagenesis and transcriptional analysis of a mouse ribosomal interferon genes in Chinese hamster ovary tells, 3964 promoter element, 2137 Distribution of reversing factor id reticulocyte lysates during active Ribosomal protein protein synthesis and on inhibition by heme deprivation or double- Nuclease protection analysis of ribonucleoprotein complexes: Use of the stranded RNA, 6998 cytotoxic ribonuclease a-sarcin to determine the binding sites for RNA hybridization Escherichia coli ribosomal proteins L5, L18, and L25 on 5S rRNA, 322 Chemically modified nucleic acids as immunodetectable probes in Ribosomal protein L11 hybridization experiments, 3466 Translational regulation of the 11 ribosomal protein operon of RNA methylation Escherichia coli: Analysis of the mRNA target site using Mapping of N6-methyladenosine residues in bovine prolactin oligonucleotide-directed mutagenesis, 5389 mRNA, 5667 Rlbosomal protein S6 RNA, nuclear Phorbol ester, serum, and Rous sarcoma virus transforming gene product Organ-specific nuclear RNAs in tobacco, 2801 induce similar phosphorylations of ribosomal protein S6, 6408 RNA, poly(A)+ Ribosomal protein S10 Identification and primary sequence of an unspliced human urokinase Formation of termination-resistant transcription complex at phage X nut poly(A)+ JZNA, 4727 locus: Effects of altered translation and a ribosomal mutation, 3612 Transient complementation of xeroderma pigmentosum cells by Ribosomal RNA of See also RNA, ribosomal microinjection poly(A)+ RNA, 5676 RNase III cleavage is obligate for maturation but not for function of Escherichia coli pre-23S rRNA, 185 Biological Sciences Subject Index Proc. NatL. Acad. Sci. USA 81 (1984) 8127

RNA polymerase RNA, viral Glucocorticoid inhibition of initiation of transcription of the DNA Simultaneous in situ detection of viral RNA and antigens, 5445 encoding rRNA (rDNA) in lymphosarcoma P1798 cells, 718 RNA virus Localization of RNA polymerase I in interphase cells and mitotic DNA and RNA virus species are inhibited by xanthates, a class of chromosomes by light and electron microscopic antiviral compounds with unique properties, 3263 immunocytochemistry, 1431 Characterization of leader RNA sequences on the virion and mRNAs of Purification of cowpea mosaic virus RNA replication complex: mouse hepatitis virus, a cytoplasmic RNA virus, 3626 Identification of a virus-encoded 110,000-dalton polypeptide responsible Striking similarities in amino acid sequence among nonstructural proteins for RNA chain elongation, 1951 encoded by RNA viruses that have dissimilar genomic Cloning and expression of the gene for bacteriophage T7 RNA organization, 4358 polymerase, 2035 Multicomponent RNA plant virus infection derived from cloned viral In vitro mutagenesis and transcriptional analysis of a mouse ribosomal cDNA, 7066 promoter element, 2137 RNase Identification, molecular cloning, and mutagenesis of Saccharomyces See ribonuclease cerevisiae RNA polymerase genes, 2157 Ro ribonucleoproteins A precise termination site in the mouse J3mair-globin transcription unit (Correction), 2274 The Ro small. cytoplasmic ribonucleoproteins: Identification of the Accurate initiation of human E-globin RNA synthesis by Escherichia coli antigenic protein and its binding site on the Ro RNAs, 1996 RNA polymerase in isolated nuclei of K562 erythroleukemia cells, 4051 Rod outer segment Detecting protein-DNA interactions in vivo: Distribution of RNA Rod light response augmented by active phosphodiesterase, 616 polymerase on specific bacterial genes, 4275 Root tip Optimal conditions for cell-free synthesis of citrus exocortis viroid and Mechanism of cytoplasmic pH regulation in hypoxic maize root tips and the question of specificity of RNA polymerase activity, 4429 its role in survival under hypoxia, 3379 Defining a bacteriophage T4 late promoter: Bacteriophage T4 gene 55 Rop protein protein suffices for directing late promoter recognition, 5101 cis-acting mutations that affect rop protein control of plasmid copy In vitro transcription of a silkworm 5S RNA gene requires an upstream number, 4465 signal, 5519 Rotational diffusion Isolation of an active transcription initiation complex from HeLa cell-free Evidence for rotational contribution to protein-facilitated proton a extract, 5916 transport, 1710 Pausing and premature termination of human RNA polymerase II during Rous sarcoma virus transcription of adenovirus in vivo and in vitro, 5931 Alteration of neural cell adhesion molecule (N-CAM) expression after Proximal and distal domains that control in vitro transcription of the neuronal cell transformation by Rous sarcoma virus, 969 adenovirus IVa2 gene, 6290 Evidence that the Rous sarcoma virus transforming gene product A purified fraction containing RNA polymerase I that can accurately phosphorylates phosphatidylinositol and diacylglycerol, 2117 transcribe rat ribosomal RNA gene, 6672 Transformation by Rous sarcoma virus prevents acetylcholine receptor Antiterminatioq of transcription from an Escherichia coli ribosomal RNA clustering on cultured chicken muscle fibers, 2265 promoter, 6789 Decrease of tyrosine-O-sulfate-containing proteins found in rat fibroblasts Regulation of polyomavirus transcription by large tumor antigen, 6919 infected with Rous sarcoma virus or Fujinami sarcoma virus, 3695 Isolated uterine nuclei and cytosol receptors of aged rats exhibit impaired Rous sarcoma virus variants that carry the cellular src gene instead of the estrogenic stimulation of RNA polymerase II, 7481 viral src gene cannot transform chicken embryo fibroblasts, 4424 RNA processing Phorbol ester, serum, and Rous sarcoma virus transforming gene product 3' editing of nmRNAs: Sequence requirements and involvement of a 60- induce similar phosphorylations of ribosomal protein S6, 6408 nuclebtide RNA in maturation of histone mRNA precursors, 1057 rRNA Requirement for the 3' flanking region of the bovine growth hbrmone See Ribosomal RNA and RNA, ribosomal gene for accurate polyadenylylation, 3944 RU 486 Glucocorticoid-mediated induction of a,-acid glycoprotein: Evidence for RU 486: A steroid with antiglucocorticosteroid activity that only hormone-regulated RNA processing, 4241 disinhibits the human pituitary-adrenal system at a specific time of Antibodies of the secondary response can be expressed without switch day, 3879 recombination in normal mouse B cells, 7189 Runaway replicon Isolation of the heterogeneous nuclear RNA-ribonucleoprotein complex Role of mRNA translational efficiency in bovine growth hormone (hnRNP): A unique supramolecular assembly, 7471 expression in Escherichia coli, 5403 RNA replication Rye Synthesis of the templates for influenza virion RNA replication in Lamellar-to-hexogonall, phase transitions in the plasma membrane of vitro, 4682 isolated protoplasts after freeze-induced dehydration, 6373 RNA replication complex Purification of cowpea mosaic virus RNA replication complex: S100 fraction Identification of a virus-encoded 110,000-dalton polypeptide responsible Production and characterization of monoclonal antibodies with specificity for RNA chain elongation, 1951 for the S100,3 polypeptide of brain S100 fractions, 6034 RNA, ribosomal S antigen See also Ribosomal RNA Differential antibody screening of cloned Plasmodium falciparum Determination of the promoter region of mouse ribosomal RNA gene by sequences expressed in Escherichia coli: Procedure for isolation of an in vitro transcription system, 299 defined antigens and analysis of human antisera, 2456 Nuclease protection analysis of ribonucleoprotein complexes: Use of the S complex cytotoxic ribonuclease a-sarcin to determine the binding sites for The 64-kilodalton membrane protein of Bacillus subtilis is also present as Escherichia coli ribosomal proteins L5, L18, and L25 on SS rRNA, 322 a multiprotein complex on membrane-free ribosomes, 7772 Quantitation of aflatoxin B1 adduction within the ribosomal RNA gene S sequences of rat.liver DNA, 664 peptide Glucocorticoid inhibition of initiation of transcription of the DNA Kinetic circular dichroism shows that the S-peptide a-helix of encoding rRNA (rDNA) in lymphosarcoma P1798 cells, 718 ribonuclease S unfolds fast and refolds slowly, 7674 Determination of the promoter region of mouse ribosomal RNA gene by Sable vaccine an in vitro transcription system (Correction), 2587 Comparison of the complete nucleotide sequences of the genomes of the The [poky] mutant of Neurospora contains a 4-base-pair deletion at the 5' neurovirulent poliovirus P3/Leon/37 and its attenuated Sabin vaccine end of the mitochondrial small rRNA, 3791 derivative P3/Leon 12alb, 1539 RNA, 5S Saccharide In vitro transcription of a silkworm 5S RNA gene requires an upstream Evaluation of critical groups required for the binding of heparin to signal, 5519 antithrombin, 1030 RNA, small cytoplasmic Saccharoiyces The Ra small cytoplasmic ribonucleoproteins: Identification of the See also Yeast antigenic protein add on the Steps in processing of the mitochondrial cytochrome oxidase subunit I its binding site Ro RNAs, 1996 pre-mRNA affected by. a nuclear mutation in yeast, 8 RNA, small nuclear Identification of a labile protein involved in the GI-to-S transition in Clustered genes for human U2 RNA, 3811 Saccharomyces cerevisiae, 120 Human Ul RNA genes contain an unusually sensitive nuclease S1 Molecular cloning of hormone-responsive genes from the yeast cleavage site within the conserved 3' flanking region, 7288 Saccharomyces cerevislae, 1144 Intron splicing: A conserved internal signal in introns of animal pre- Specificity of polyamine requirements for the replication and maintenance mRNAs, 7417 of different double-stranded RNA plasmids in Saccharomyces RNA splicng cerevisiae, 1149 $-Thalassemia in Chinese' Use of in vivo RNA analysis and Identification, molecular cloning, and mutagenesis of Saccharomyces oligonucleotide hybridization in systematic characterization of cerevisiae RNA polymerase genes, 2157 molecular defects, 2821 Ty-mediated gene expression of the L YS2 and HIS4 genes of Identification and primary sequence of an unspliced human urokinase Saccharomyces cerevisiae is controlled by the same SPT genes, 2431 poly(A)+ RNA, 4727 DNA topoisomerase II mutant of Saccharomyces cerevisiae: A single rat fibronectin geie generates three different mRNAs by Topoisomerase II is required for segregation of daughter molecules at alternative splicing of a complex exon, 5140 the termination of DNA replication, 2616 Intron splicing: A conserved internal signal in introns of animal pre- MAL6 of Saccharomyces: A complex genetic locus containing three mRNAs, 7417 genes required for maltose fermentation, 2811 RNA structure tau, a repeated DNA sequence in yeast, 2965 RNA structure analysis using methidiumpropyl-EDTA-Fe(II): A base- a-Factor-directed synthesis and secretion of mature foreign proteins in pair-specific RNA structure probe, 6978 Saccharomyces cerevisiae, 4642 8128 Biological Sciences Subject Index Proc. NatL Acad ScL USA 81 (1984)

Identification of 17f3-estradiol as the estrogenic substance in Schistosomiasis Saccharomyces cerevisiae, 4722 Schistosoma mansoni egg granuloma size reduction in challenged Construction and genetic characterization of temperature-sensitive mutant baboons after vaccination with irradiated cryopreserved alleles of the yeast actin gene, 4889 schistosomula, 3552 Secretion of foreign proteins from Saccharomyces cerevisiae directed by Schizophrenia a-factor gene fusions, 5330 Chaotic behavior in dopamine neurodynamics, 1244 Yeast gene CDC8 encodes thymidylate kinase and is complemented by Schizosaccharomyces herpes thymidine kinase gene TK, 5821 Genes required for initiation and resolution steps of mating-type switching Photoaffinity labeling and characterization of the cloned purine-cytosine in fission yeast, 3481 transport system in Saccharomyces cerevisiae, 6276 Schwann cell Isolation of glucose-containing high-mannose glycoprotein core Schwann cell expression of a major myelin glycoprotein in the absence of oligosaccharides, 6340 myelin assembly, 1864 Expression of a human a1-antitrypsin cDNA in the yeast Saccharomyces Schwann cell proliferation and localized proteolysis: Expression of cerevisiae, 6594 plasminogen-activator activity predominates in the proliferating cell Upstream activation sites of the CYCI gene of Saccharomyces cerevisiae populations, 7216 are active when inverted but not when placed downstream of the Sdnicanning "TATA box", 7860 Imaging of hepatic low density lipoprotein receptors by radionuclide Sacculus scintiscanning in vivo, 7599 Molecular model for elongation of the murein sacculus of Escherichia Scutellum coli, 1844 Regulation of Cat] gene expression in the scutellum of maize during early Saimbi sporophytic development, 4903 Protective immunization of the squirrel monkey against asexual blood Sea urchin stages of Plasmodium falciparum by use of parasite protein Temporal expression of late histone messenger RNA in the sea urchin fractions, 229 Lytechinus pictus, 2411 Salivary gland Inducible expression of a cloned heat shock fusion gene in sea urchin Evidence for physiological function of epidermal growth factor: embryos, 7490 Pregestational sialoadenectomy of mice decreases milk production and Search increases offspring mortality during lactation period, 6059 Search, encounter rates, and the evolution of anisogamy, 6078 Salivary protein Searchliht hypothesis Clones from the human gene complex coding for salivary proline-rich Function of the thalamic reticular complex: The searchlight proteins, 5561 hypothesis, 4586 Salmonella Spontaneous and mutagen-induced deletions: Mechanistic studies in Seasonlity Salmonella tester strain TA102, 4457 Seasonal aggression independent of seasonal testosterone in wood Genetic recombination can generate altered restriction specificity, 6095 rats, 5255 Suppressor sufJ: A novel type of tRNA mutant that induces translational Secate frameshifting, 6105 Lamellar-to-hexogonalIi phase transitions in the plasma membrane of Salt bridge isolated protoplasts after freeze-induced dehydration, 6373 Stability of "salt bridges" in membrane proteins, 5412 Second messenger Saponin Cyclic GMP may serve as a second messenger in peptide-induced muscle myo-Inositol 1,4,5-trisphosphate stimulates protein phosphorylation in degeneration in an insect, 6718 saponin-permeabilized human platelets, 7431 Secondary response a-Sarcin Antibodies of the secondary response can be expressed without switch Nuclease protection analysis of ribonucleoprotein complexes: Use of the recombination in normal mouse B cells, 7189 cytotoxic ribonuclease a-sarcin to determine the binding sites for Secondary sexual character Escherichia coli ribosomal proteins L5, L18, and L25 on 5S rRNA, 322 Artificial selection for a secondary sexual character in males of Sarcolemma Drosophila silvestris from Hawaii, 3915 Monoclonal antibodies against the voltage-sensitive Na+ channel from Secondary structure prediction mammalian skeletal muscle, 6227 Predicted secondary structure similarity in the absence of primary amino Identification and partial purification of the cardiac sodium-calcium acid sequence homology: Hepatitis B virus open reading frames, 2902 exchange protein, 6569 The structure of bovine brain myelin proteolipid and its organization in Sarcoma cell myelin, 2912 Invasive behavior of mouse sarcoma cells is inhibited by blocking a Secreted H-2 antigen 37,000-dalton plasma membrane glycoprotein with Fab fragments, 3747 Detection of a secreted form of the murine H-2 class I antigen with an Sarcoma virus antibody against its predicted carboxyl terminus, 1216 Chromosome assignments of four mouse cellular homologs of sarcoma Secretion and leukemia virus 525 Monoclonal antibodies as probes for unique antigens in secretory cells of oncogenes, mixed exocrine organs, 4419 Sarcomere Secretor Titin is an extraordinarily long, flexible, and slender myofibrillar Biochemical evidence that secretor gene, Se, is a structural gene protein, 3685 encoding a specific fucosyltransferase, 4193 Sarcophaga Secretory granule Hormonal control of eclosion of flies from the puparium, 1457 Spiperone: Evidence for uptake into secretory granules, 1867 Sarcoplasmic reticulum Carboxypeptidase B-like converting enzyme activity in secretory granules Ca2+-ATPase of the sarcoplasmic reticulum shares a common domain of rat pituitary, 2776 with a membrane glycoprotein associated with the cytoskeleton of Secretory protein microvilli, 1130 Balbiam ring induction in phosphate metabolism, 1448 Sequence homology between two membrane transport ATPases, the Kdp- ATPase of Escherichia coli and the Ca +-ATPase of sarcoplasmic Sedation reticulum, 4746 Spider sedation induced by defensive chemicals of milliped prey, 806 Monomeric solubilized sarcoplasmic reticulum Ca pump protein: Selection Demonstration of Ca binding and dissociation coupled to ATP Artificial selection for a secondary sexual character in males of hydrolysis, 6623 Drosophila silvestris from Hawaii, 3915 Satellite DNA Maintenance of high disequilibrium in the presence of partial selfing, 4596 Minichromosomal repetitive DNA in Trypanosoma cruzi: Its use in a Selection, fr-equency-dependent detection 3356 Evolutionary principles for polynomial models of frequency-dependent high-sensitivity parasite assay, selection, 2840 Selenium Lotka's roots under rescalings, 3600 Distribution of two selenonucleosides among the selenium-containing Scallop tRNAs from Methanococcus vannielfi, 57 Movement of scallop myosin on Nitella actin filaments: Regulation by Occurrence of selenium-containing tRNAs in mouse leukemia cells, 3010 calcium, 6775 Effect of selenium deficiency on cuticle integrity in the Cladocera Schiff base (Crustacea), 3433 Dark-adapted bacteriorhodopsin contains 13-cis,15-syn and all-trans,15- anti retinal Schiff bases, 1706 Selenonucleoside Determination of retinal Schiff base configuration in Distribution of two selenonucleosides among the selenium-containing bacteriorhodopsin, 2055 tRNAs from Methanococcus vannielii, 57 Retinal migration during dark reduction of bacteriorhodopsin, 2303 Self-organization On the protein (tyrosine)-chromophore (protonated Schiff base) coupling Self-organization in macromolecular systems: The notion of adaptive in bacteriorhodopsin, 7083 value, 6068 Schistosoma Self-repair Differentiation of schistosomes by species, strain, and sex by using Understanding biological computation: Reliable learning and cloned DNA markers, 889 recognition, 6871 Schistosoma mansoni egg granuloma size reduction in challenged Self-stimulation baboons after vaccination with irradiated cryopreserved Changes in local cerebral glucose utilization during rewarding brain schistosomula, 3552 stimulation, 635 Se"Maintenance of high disequilibrium in the presence of partial selfing, 4596 Biological Sciences Subject Index Proc. Nati. Acad. Sci. USA 81 (1984) 8129

Sellers TT algorithm Serum dependence Internal duplication in human a, and- ,8 interferons, 7171 Biological activities of v-myc and rearranged c-myc oncogenes in rat Seminiferous cord fibroblast cells in culture, 5758 Dissociation between testicular organogenesis and endocrine Serum-free cell culture cytodifferentiation of Sertoli cells, 7831 Long-term cultivation and differentiation of human erythroleukemia cells Semispecies in a protein-free chemically defined medium, 453 Streptococcal L-forms isolated from Drosophila paulistorum semispecies Neurotrophic factor for central neurons, 1248 cause sterility in male progeny, 282 Brain- and liver cell-derived factors are required for growth of human Sendai virus endothelial cells in serum-free culture, 6413 Sendai virus-specific T-cell clones: Induction of cytolytic T cells by an Serum-fre medium anti-idiotypic antibody directed against a helper T-cell clone, 2850 Hepatocyte proliferation in vitro: Its dependence on the use of serum-free Expression of Epstein-Barr virus (EBV) DNA and cloned DNA hormonally defined medium and substrata of extracellular matrix, 1411 fragments in human lymphocytes following Sendai virus envelope- Neuroblastoma cells produce transforming growth factors during mediated gene transfer, 5926 exponential growth in a defined hormone-free medium, 4085 Analysis of Sendai virus mRNAs with cDNA clones of viral genes and Serum-free growth of human mammary epithelial cells: Rapid clonal sequences of biologically important regions of the fusion protein, 7732 growth in defined medium and extended serial passage with pituitary Senescence extract, 5435 Lipid peroxidation forms ethylene from 1-aminocyclopropane-1- Serum substance carboxylic acid and may operate in leaf senescence, 1724 Genes for murine fourth complement component (C4) and sex-limited Calmodulin inhibitor in senescing apples and its physiological and protein (Slp) identified by hybridization to C4- and Slp-specific pharmacological significance, 2065 cDNA, 4908 Senescent cell antigen Set-dependent response Localization of senescent cell antigen on band 3, 5753 Tonically discharging putamen neurons exhibit set-dependent Sensitization responses, 4998 Branch-specific heterosynaptic facilitation in Aplysia siphon sensory Sex-limited protein cells, 2577 Genes for murine fourth complement component (C4) and sex-limited Serotonin increases intracellular Ca2+ transients in voltage-clamped protein (Sip) identified by hybridization to C4- and Slp-specific sensory neurons of Aplysia californica, 7642 cDNA, 4908 Sensory ganglia Isolation of cDNA clones specifying the fourth component of mouse Biochemical and anatomical effects of antibodies against nerve growth complement and its isotype, sex-limited protein, 6822 factor on developing rat sensory ganglia, 1580 Sexual dimorphism Sensory neuron Inheritance of a secondary sexual character in Drosophila silvestris, 6904 Serotonin increases intracellular Ca2' transients in voltage-clamped Shell sensory neurons of Aplysia californica, 7642 Snail shape and growth rates: Evidence for plastic shell allometry in Sensory receptor molecule Littorina littorea, 811 Membrane proteins unique to vertebrate olfactory cilia: Candidates for Shiverer mutant sensory receptor molecules, 1859 Cultures of shiverer mutant cerebellum injected with normal Sensory response oligodendrocytes make both normal and shiverer myelin, 2558 Cerebellum mediates modality-specific modulation of sensory responses Shpolskii matrix of midbrain and forebrain in rat, 2917 Proton-transfer spectroscopy of 3-hydroxyflavone in an isolated-site Sensory transducer crystal matrix, 3375 Structure of the Trg protein: Homologies with and differences from other Shuttle vector sensory transducers of Escherichia coli, 3287 Construction of shuttle vectors capable of conjugative transfer from Sensory transduction Escherichia coli to nitrogen-fixing filamentous cyanobacteria, 1561 Rod light response augmented by active phosphodiesterase, 616 Plasmid transfer from Escherichia coli to Bacteroides fragilis: Differential The role of a signaling protein in bacterial sensing: Behavioral effects of expression of antibiotic resistance phenotypes, 7203 increased gene expression, 5056 Sensory transduction in Escherichia coli: Regulation of the demethylation Detection of erythrocyte membrane proteins, , and rate by the CheA protein, 5061 lipids in the same polyacrylamide gel using a double-staining Septation technique, 1733 Cell-division control in Escherichia coli: Specific induction of the SOS Differentiation of human erythroid cells is associated with increased 0- function SfiA protein is sufficient to block septation, 4490 glycosylation of the major sialoglycoprotein, A, 6752 Sequence homology Sialyltransferase On the use of sequence homologies to predict protein structure: Identical Use of prokaryotic-derived probes to identify poly(sialic acid) in neonatal pentapeptides can have completely different conformations, 1075 neuronal membranes, 1971 Isolation and characterization of a cDNA clone for the complete protein Sickle cell disease coding region of the 8 subunit of the mouse acetylcholine Origin of the As-globin gene in Blacks: The contribution of recurrent receptor, 7970 mutation or gene conversion or both, 853 Structure, linkage, and sequence of the two genes encoding the 8 and y Potential use of biaromatic L-phenylalanyl derivatives as therapeutic subunits of the nicotinic acetylcholine receptor, 7975 agents in the treatment of sickle cell disease, 3190 Serine protease Sickle cell hemoglobin Isolation of cDNA clones for human complement component C2, 1212 Evidence for the multicentric origin of the sickle cell hemoglobin gene in The structure of the human tissue-type plasminogen activator gene: Africa, 1771 Correlation of intron and exon structures to functional and structural Signal hypothesis domains, 5355 Determinants for protein localization: ,B-Lactamase signal sequence Serotonin directs globin across microsomal membranes, 456 Serotonin binds specifically and saturably to an actin-like protein isolated Si-alW peptidase from rat brain synaptosomes, 959 Nucleotide sequence of the Escherichia coli prolipoprotein signal Evidence for parallel actions of a molluscan neuropeptide and serotonin peptidase (Isp) gene, 3708 in mediating arousal in Aplysia, 2934 Sinal recognition particle Mutations in the dopa decarboxylase gene affect learning in Signal recognition particle is required for co-translational insertion of Drosophila, 3577 cytochrome P450 into microsomal membranes, 3361 Requirement for protein synthesis in the regulation of a circadian rhythm Signal sequence by serotonin, 7637 Chimeric influenza virus hemagglutinin containing either the NH2 Serotonin increases intracellular Ca2+ transients in voltage-clamped terminus or the COOH terminus of G protein of vesicular stomatitis sensory neurons of Aplysia californica, 7642 virus is defective in transport to the cell surface, 395 Two endogenous neuropeptides modulate the gill and siphon withdrawal NH2-terminal hydrophobic region of influenza virus neuraminidase reflex in Aplysia by presynaptic facilitation involving cAMP-dependent provides the signal function in translocation, 2327 closure of a serotonin-sensitive potassium channel, 7956 Signal recognition particle is required for co-translational insertion of Serotonin receptor cytochrome P450 into microsomal membranes, 3361 Spiperone: Evidence for uptake into secretory granules, 1867 Intragenic regions required for LamB export, 3830 Sertoli cell Secretion of human parathyroid hormone from rat pituitary cells infected Dissociation between testicular organogenesis and endocrine with a recombinant retrovirus encoding preproparathyroid cytodifferentiation of Sertoli cells, 7831 hormone, 5340 Serum Rat liver asialoglycoprotein receptor lacks a cleavable NH2-terminal Phorbol ester, serum, and Rous sarcoma virus transforming gene product signal sequence, 7338 induce similar phosphorylations of ribosomal protein S6, 6408 Signal transduction Serum albumin The role of a signaling protein in bacterial sensing: Behavioral effects of 9-Deoxy-_9,A92-13,14-dihydroprostaglandin D2, a metabolite of increased gene expression, 5056 prostaglandin D2 formed in human plasma, 1317 Signature analysis Linkage disequilibrium and evolutionary relationships of DNA variants Hepatitis B viral antigenic structure: Signature analysis by monoclonal (restriction enzyme fragment length polymorphisms) at the serum radioimmunoassays, 2237 albumin locus, 3486 Silk gland Synthesis in animal cells of hepatitis B surface antigen particles carrying Natural fibroin genes purified without using cloning procedures from a receptor for polymerized , 7708 fibroin-producing and -nonproducing tissues reveal indistinguishable structure and function, 1644 8130 Biological Sciences Subject Index Proc. NatL Acad. Sci. USA 81 (1984)

Silkmoth Sodium absorption Molecular cloning of region-specific chorion-encoding RNA Cell swelling increases a barium-inhibitable potassium conductance in the sequences, 27% basolateral membrane of Necturus small intestine, 3591 DNA sequence transfer between two high-cysteine chorion gene families Sodium channel in the silkmoth Bombyx mori, 4452 Electrical activity and cytosolic calcium regulate levels of tetrodotoxin- Silkworm sensitive sodium channels in cultured rat muscle cells, 262 In vitro transcription of a silkworm 5S RNA gene requires an upstream Reconstitution of neurotoxin-modulated ion transport by the voltage- signal, 5519 regulated sodium channel isolated from the electroplax of Silver stain Electrophorus electricus, 1239 Detection of erythrocyte membrane proteins, sialoglycoproteins, and Single-channel properties of the reconstituted voltage-regulated Na lipids in the same polyacrylamide gel using a double-staining channel isolated from the electroplax of Electrophorus electricus, 5594 technique, 1733 Monoclonal antibodies against the voltage-sensitive Na' channel from Simian sarcoma virus mammalian skeletal muscle, 6227 Blockade of autocrine stimulation in simian sarcoma virus-transformed Sodium chloride cells reverses down-regulation of platelet-derived growth factor Salt-induced Z-A-Z transition sequence in the mixed ribo-deoxyribo receptors, 7466 copolymer poly(rG-dC)poly(rG-dC), 7284 Simian virus 5 Sodium flux Fusion protein of the paramyxovirus simian virus 5: Nucleotide sequence Cell growth and net Na+ flux are inhibited by a protein produced by of mRNA predicts a highly hydrophobic glycoprotein, 6706 kidney epithelial cells in culture, 793 Simian virus 40 Sodium-glucose cotransporter Mapping of the late promoter of simian virus 40, 23 Conformational changes in the intestinal brush border sodium-glucose Identification of Epstein-Barr nuclear antigen polypeptide in mouse and cotransporter labeled with fluorescein isothiocyanate, 2223 monkey cells after gene transfer with a cloned 2.9-kilobase-pair Sodium pump subfragment of the genome, 43 Na+ movement in a single turnover of the Na pump, 5310 Stimulation of in vitro transcription from heterologous promoters by the Sodium transport simian virus 40 enhancer, 308 Two different Na,K-ATPases in the optic nerve: Cells of origin and Stimulation of simian virus 40 late gene expression by simian virus 40 axonal transport, 1234 tumor antigen, 2040 Mouse primase initiation sites in the origin region of simian virus 40, 2342 Sodium/calcium exchange Nature and origin of the RNA associated with simian virus 40 large tumor Inhibition of Na+/Ca2+ exchange in membrane vesicle and papillary antigen, 5425 muscle preparations from guinea pig heart by analogs of amiloride, 3238 The simian virus 40 minimal origin and the 72-base-pair repeat are Isolation, purification, and reconstitution of the Na+ gradient-dependent required simultaneously for efficient induction of late gene expression Ca2+ transporter (Na'-Ca + exchanger) from brain synaptic plasma with large tumor antigen, 6335 membranes, 6521 Quantitative assay for albumin-producing liver cells after simian virus 40 Identification and partial purification of the cardiac sodium-calcium transformation of rat hepatocytes maintained in chemically defined exchange protein, 6569 medium, 6378 Sodium/hydrogen antiport Specific in vitro adenylylation of the simian virus 40 large tumor A specific mutation abolishing Na+/H+ antiport activity in hamster antigen, 6574 fibroblasts precludes growth at neutral and acidic pH, 4833 A viable simian virus 40 variant that carries a newly generated sequence Sodium/hydrogen exchange reiteration in place of the normal duplicated enhancer element, 6652 Na+-HW exchange activity in renal brush border membrane vesicles in Simian virus 40 DNA replication in vitro, 6973 response to metabolic acidosis: The role of glucocorticoids, 630 Simian virus 40 T antigen is required for viral excision from Inhibition of epidermal growth factor-induced mitogenesis by amiloride chromosomes, 7534 and an analog: Evidence against a requirement for Na+/H+ Sindbis virus exchange, 6762 Striking similarities in amino acid sequence among nonstructural proteins Soft agar growth encoded by RNA viruses that have dissimilar genomic Specific binding to cultured cells of I251-labeled type (3 transforming organization, 4358 growth factor from human platelets, 6757 Single-base substitution Soldier Enzymatic techniques for the isolation of random single-base Soldier formation regulated by a primer pheromone from the soldier substitutions in vitro at high frequency, 2030 frontal gland in a higher termite, Nasutitermes lujae, 7665 Enzymatic techniques for the isolation of random single-base Soliton substitutions in vitro at high frequency (Correction), 4599 Soliton-assisted unidirectional circulation in a biochemical cycle, 4386 Single-stranded DNA binding protein Solution Mechanism of the concerted action of recA protein and helix-destabilizing The effects of water-soluble solutes on the phase transitions of proteins in homologous recombination, 2757 phospholipids, 1398 Siphon Somatic activation Two endogenous neuropeptides modulate the gill and siphon withdrawal A position 12-activated H-ras oncogene in all HS578T mammary reflex in Aplysia by presynaptic facilitation involving cAMP-dependent carcinosarcoma cells but not normal mammary cells of the same closure of a serotonin-sensitive potassium channel, 7956 patient, 5384 Siphon sensory cell Somatic cell hybridization Branch-specific heterosynaptic facilitation in Aplysia siphon sensory Toxin-antitoxin selection for isolating somatic cell fusion products cells, 2577 between any cell types, 7822 Skin Somatic diversification Is ATP a central synaptic mediator for certain primary afferent fibers from mammalian skin?, 6890 Somatic diversification of immunoglobulins, 2162 Somatic mutation Sleep K gene diversity among the clonal progeny of pre-B lymphocytes, 1529 Specific absorption with monoclonal antibodies to muramyl dipeptide of Somatic diversification of immunoglobulins, 2162 the pyrogenic and somnogenic activities of rabbit monokine, 5888 Expression and rearrangement of homologous immunoglobulin VH genes Differential sleep-promoting effects of five sleep substances nocturnally in two mouse strains, 2167 infused in unrestrained rats, 6240 Generation of antibody diversity in the immune response of BALB/c mice Slime mold to influenza virus hemagglutinin, 3180 cAMP pulses coordinate morphogenetic movement during fruiting body Somatic mutation of the T15 heavy chain gives rise to an antibody with formation of Dictyostelium minutum, 2122 autoantibody specificity, 5841 Slow virus Somatocrinin Slow virus visna: Reproduction in vitro of virus from extrachromosomal Growth hormone-releasing factor regulates growth hormone mRNA in DNA, 7212 primary cultures of rat pituitary cells, 1553 Small cardioactive peptide B Isolation, primary structure, and synthesis of human hypothalamic Evidence for parallel actions of a molluscan neuropeptide and serotonin somatocrinin: Growth hormone-releasing factor, 4302 in mediating arousal in Aplysia, 2934 Somatomedin Small nuclear ribonucleoprotein Synthetic somatomedin C: Comparison with natural hormone isolated 3' editing of mRNAs: Sequence requirements and involvement of a 60- from human plasma, 740 nucleotide RNA in maturation of histone mRNA precursors, 1057 Tissue concentrations of somatomedin C: Further evidence for multiple Pulse labeling of small nuclear ribonucleoproteins in vivo reveals distinct sites of synthesis and paracrine or autocrine mechanisms of action, 935 patterns of antigen recognition by human autoimmune antibodies, 3185 Inhibition of the mitogenic effects of plasma by a monoclonal antibody to Smell somatomedin C, 2389 Ability to smell androstenone is genetically determined, 4899 Placental lactogen administration reverses the effect of low-protein diet Smooth muscle cell on maternal and fetal serum somatomedin levels in the pregnant Specific binding of leukotriene C4 to ileal segments and subcellular rat, 5853 fractions of ileal smooth muscle cells, 4529 Somatostatin Snail Inhibition of growth of pancreatic carcinomas in animal models by Snail shape and growth rates: Evidence for plastic shell allometry in analogs of hypothalamic hormones, 248 Littorina littorea, 811 Biochemical and anatomical effects of antibodies against nerve growth Sodium factor on developing rat sensory ganglia, 1580 Artifacts caused by cell microinjection, 1426 Primary structure of the gene encoding rat preprosomatostatin, 3337 Na' movement in a single turnover of the Na pump, 5310 Na'-H' exchange in gastric glands as measured with a cytoplasmic- trapped, fluorescent pH indicator, 7436 Biological Sciences Subject Index Proc. NatL Acad. Sci. USA 81 (1984) 8131

Neuropeptide-containing neurons of the cerebral cortex are also Sporulation GABAergic, 6526 Selective expression of a plasmid cat gene at a late stage of Bacillus Enzymes processing somatostatin precursors: An Arg-Lys subtilis sporulation, 3457 esteropeptidase from the rat brain cortex converting somatostatin-28 Nucleotide sequence of the spoOB gene of Bacillus subtilis and regulation into somatostatin-14, 6662 of its expression, 7012 Characterization of a somatostatin-28 containing the (Tyr-7, Gly-10) Photomorphogenesis in Physarum: Induction of tubulins and sporulation- derivative of somatostatin-14: A terminal active product of specific proteins and of their mRNAs, 7117 prosomatostatin II processing in anglerfish pancreatic islets, 7003 Changing patterns of gene expression during sporulation in yeast, 7323 Somitic myotome Squamous cell carcinoma Immunofluorescence analysis of the primordial myosin detectable in Differences in keratin synthesis between normal epithelial cells and embryonic striated muscle, 797 squamous cell carcinomas are mediated by vitamin A, 4280 Sorghum Squid Pepsin digestibility of proteins in sorghum and other major cereals, 1 Squid rhodopsin and GTP-binding protein crossreact with vertebrate SOS response photoreceptor enzymes, 5111 Mutational specificity of depurination, 1494 Squirrel monkey groEL and dnaK genes of Escherichia coli are induced by UV irradiation Protective immunization of the squirrel monkey against asexual blood and nalidixic acid in an htpR+-dependent fashion, 1499 stages of Plasmodium falciparum by use of parasite protein Cell-division control in Escherichia coli: Specific induction of the SOS fractions, 229 function SfiA protein is sufficient to block septation, 4490 Stable population theory Involvement of the activated form of RecA protein in SOS mutagenesis Lotka's roots under rescalings, 3600 and stable DNA replication in Escherichia coli, 7539 Staphylococcal enterotoxin A Spacer DNA Staphylococcal enterotoxin A gene is associated with a variable genetic Ribosomal DNA spacer-length polymorphisms in barley: Mendelian element, 5179 inheritance, chromosomal location, and population dynamics, 8014 Starvation Speciation Induction of two genes by glucose starvation in hamster fibroblasts, 988 Differentiation of schistosomes by species, strain, and sex by using Requirement for alanine in the amino acid control of deprivation-induced cloned DNA markers, 889 protein degradation in liver, 4270 Artificial selection for a secondary sexual character in males of StereoIsomer Drosophila silvestris from Hawaii, 3915 A simple topological method for describing stereoisomers of DNA Genetic basis of male sterility in hybrids between two closely related catenanes and knots, 3322 species of Drosophila, 4444 Steroid Repeatability of taxon longevity in successive foraminifera radiations and Molecular cloning and nucleotide sequence of cDNA for mRNA of a theory of random appearance and extinction, 5478 mitochondrial cytochrome P-450(SCC) of bovine adrenal cortex, 4647 Inheritance of a secondary sexual character in Drosophila silvestris, 6904 Identification of 17f-estradiol as the estrogenic substance in Spectrin Saccharomyces cerevisiae, 4722 Monoclonal antibodies detect a spectrin-like protein in normal and Steroid biosynthesis dystrophic human skeletal muscle, 776 Calcium-dependent, cyclic nucleotide-independent steroidogenesis in the Goblin (ankyrin) in striated muscle: Identification of the potential bovine placenta, 6403 membrane receptor for erythroid spectrin in muscle cells, 3292 Steroid hormone Brain fodrin: Substrate for calpain I, an endogenous calcium-activated protease, 3572 Injection of partially purified estrogen receptor protein from Xenopus A structural model of human erythrocyte band 2.1: Alignment of chemical liver nuclei into oocytes activates the silent vitellogenin locus, 5777 and functional domains, 4095 Steroid 21-hydroxylation Sperm Cloning and expression of cDNA encoding a bovine adrenal cytochrome Characterization of a membrane antigen from rabbit testis and sperm P450 specific for steroid 21-hydroxylation, 1986 isolated by using monoclonal antibodies and effect of its antiserum on HLA-linked congenital adrenal hyperplasia results from a defective gene fertility, 857 encoding a cytochrome P-450 specific for steroid 21- Time and voltage windows for reversing the electrical block to hydroxylation, 7505 fertilization, 1436 Steroid receptor Interaction of the la,25-dihydroxyvitamin D3 receptor with RNA and Spermidine synthetic polyribonucleotides, 2337 Specificity of polyamine requirements for the replication and maintenance Contacts between hormone receptor and DNA double helix within a of different double-stranded RNA plasmids in Saccharomyces glucocorticoid regulatory element of mouse mammary tumor cerevisiae, 1149 virus, 3029 Spermophilus Contacts between hormone receptor and DNA double helix within a Rapid recovery of body mass after surgical removal of adipose tissue in glucocorticoid regulatory element of mouse mammary tumor virus ground squirrels, 2270 (Correction), 5892 Spider Glucocorticoid-sensitive hippocampal neurons are involved in terminating Spider sedation induced by defensive chemicals of milliped prey, 806 the adrenocortical stress response, 6174 Spider venoms inhibit L-glutamate binding to brain synaptic membrane Sterol receptors, 5571 Plasma membrane biogenesis in eukaryotic cells: Translocation of newly Spinal cord synthesized lipid, 1385 Monoclonal antibodies and peptide mapping reveal structural similarities Evidence for the presence of makisterone A in Drosophila larvae and the between the subunits of the glycine receptor of rat spinal cord, 7224 secretion of 20-deoxymakisterone A by the ring gland, 5643 Spiperone Sterol carrier protein Spiperone: Evidence for uptake into secretory granules, 1867 Intramitochondrial movement of adrenal sterol carrier protein with Dopamine receptor turnover rates in rat striatum are age-dependent, 3910 cholesterol in response to corticotropin, 2970 Spiodela Stilbenedisulfonate Regulation of protein metabolism: Coupling of photosynthetic electron Dimeric structure of single chloride channels from Torpedo transport to in vivo degradation of the rapidly metabolized 32-kilodalton electroplax, 2772 protein of the chloroplast membranes, 1380 Stimulus-secretion coupling Spleen cell Inhibitors of CDP-choline synthesis, action potential calcium channels, Specific binding of erythropoietin to spleen cells infected with the anemia and stimulus-secretion coupling, 4353 strain of Friend virus, 7574 Stochastic mechanism Spleen virus Disparate differentiation in mouse hemopoietic colonies derived from The retrovirus pol gene encodes a product required for DNA integration: paired progenitors, 2520 Identification of a retrovirus int locus, 7885 Storage protein Splenin Nucleic acid (cDNA) and amino acid sequences of a-type gliadins from Contrasting biological activities of thymopoietin and splenin, two closely wheat (Triticum aestivum), 4712 related polypeptide products of thymus and spleen, 2847 Streptococcal L-form Splenomegaly Streptococcal L-forms isolated from Drosophila paulistorum semispecies Comparison of immunity to malaria in Sudan and Indonesia: Crisis-form cause sterility in male progeny, 282 versus merozoite-invasion inhibition, 922 Streptococcal M protein Splenopentin Epitope-specific protective immunogenicity of chemically synthesized Contrasting biological activities of thymopoietin and splenin, two closely 13-, 18-, and 23-residue peptide fragments of streptococcal M related polypeptide products of thymus and spleen, 2847 protein, 2203 Splice junction Streptococcus U1 RNA-protein complex preferentially binds to both 5' and 3' splice Streptokinase: Cloning, expression, and excretion by Escherichia junction sequences in RNA or single-stranded DNA, 6281 coli, 3557 Spalce sequence Hyperrecombination at a specific DNA sequence in pneumococcal An unusual 5' splice sequence is efficiently utilized in vivo, 2733 transformation, 5184 Sporangiophore Generation of deletions in pneumococcal mal genes cloned in Bacillus Phototropic response of the stage I Phycomyces sporangiophore to a subtilis, 5189 pulse of blue light, 7103 Streptokinase Photomorphogenesis in Physarum: Induction of tubulins and sporulation- Streptokinase: Cloning, expression, and excretion by Escherichia specific proteins and of their mRNAs, 7117 coli, 3557 8132 Biological Sciences Subject Index Proc. Natl. Acad. Sci USA 81 (1984)

Streptomycin resistance Superoxide dismutase Chloroplast DNA recombination in interspecific hybrids of Bis[cyclo(histidylhistidine)Icopper(II) complex that mimicks the active Chlamydomonas: Linkage between a nonmendelian locus for center of superoxide dismutase has its catalytic activity, 3283 streptomycin resistance and restriction fragments coding for 16S Isolation of the Escherichia coli iron superoxide dismutase gene: rRNA, 1164 Evidence that intracellular superoxide concentration does not regulate Stress oxygen-dependent synthesis of the manganese superoxide Physiological role of a-melanocyte-stimulating hormone in modulating the dismutase, 4970 secretion of prolactin and luteinizing hormone in the female rat, 8004 Superoxide production Stress protein Monitoring of cytosolic free Ca2+ in C5a-atimulated neutrophils: Loss of Induction of glucose-regulated proteins during anaerobic exposure and of receptor-modulated Ca2+ stores and Ca + uptake in granule-free heat-shock proteins after reoxygenation, 4843 cytoplasts, 1416 Stress response Suppression Glucocorticoid-sensitive hippocampal neurons are involved in terminating Cytotoxic T-cell precursors revealed in neonatally tolerant mice, 220 the adrenocortical stress response, 6174 Escherichia coli mutants suppressing replication-defective mutations of Striatum the ColEl plasmid, 550 Dopamine receptor turnover rates in rat striatum are age-dependent, 3910 Escherichia coli mutants suppressing replication-defective mutations of Compartmental distribution of striatal cell bodies expressing the ColEl plasmid (Correction), 2944 [Metlenkephalin-like immunoreactivity, 7980 Long terminal repeat nucleotide sequence and specific insertion of the Structure-function relationship gypsy transposon, 4462 Human liver alcohol dehydrogenase: Amino acid substitution in the M32 Transfer RNA mischarging mediated by a mutant Escherichia coli Oriental isozyme explains functional properties, establishes an active glutaminyl-tRNA synthetase, 5076 site structure, and parallels mutational exchanges in the yeast Yeast mitochondrial genomes consisting of only AFT base pairs replicate enzyme, 3024 and exhibit suppressiveness, 7156 The structure of the human tissue-type plasminogen activator gene: Suppressor Correlation of intron and exon structures to functional and structural Construction of mutants of Moloney murine leukemia virus by domains, 5355 suppressor-linker insertional mutagenesis: Positions of viable insertion mutations, 4149 Structure prediction Suppressor sufJ: A novel type of tRNA mutant that induces translational On the use of sequence homologies to predict protein structure: Identical frameshifting, 6105 pentapeptides can have completely different conformations, 1075 The sup-7(st5) X gene of Caenorhabditis elegans encodes a tRNATUAG Submaxillary gland amber suppressor, 6784 Mouse kidney and submaxillary gland renin genes differ in their 5' Directional cloning of DNA fragments at a large distance from an initial putative regulatory sequences, 5489 probe: A circularization method, 6812 Substance P Suppressor T-cell factor Biochemical and anatomical effects of antibodies against nerve growth Chronic treatment with rabbit anti-mouse u-chain antibody alters the factor on developing rat sensory ganglia, 1580 characteristic immunoglobulin heavy-chain restriction of murine Behavioral and neurochemical differentiation of specific projections in suppressor T-cell factors, 3846 the septal-hippocampal cholinergic pathway of the rat, 1880 Supramolecular organization Substance P modulation of acetylcholine-induced currents in embryonic Catalytic consuences of oligomeric organization: Kinetic evidence for chicken sympathetic and ciliary ganglion neurons, 2924 "tethered" acto-heavy meromyosin at low ATP concentrations, 5345 Substantia gelatinosa Survival Is ATP a central synaptic mediator for certain primary afferent fibers Occurrence of cell division is not exponentially distributed: Differences in from mammalian skin?, 6890 the generation times of sister cells can be derived from the theory of Subtilisin survival of populations, 2379 The subtilisin E gene of Bacillus subtilis is transcribed from a 37 Swiss 3T3 cell promoter in vivo, 1184 Microinjected pBR322 stimulates cellular DNA synthesis in Swiss 3T3 Sudan cells, 400 Comparison of immunity to malaria in Sudan and Indonesia: Crisis-form Switch recombination versus merozoite-invasion inhibition, 922 Antibodies of the secondary response can be expressed without switch Sugar recombination in normal mouse B cells, 7189 Modification of DNA by reducing sugars: A possible mechanism for Switching nucleic acid aging and age-related dysfunction in gene expression, 105 Genes required for initiation and resolution steps of mating-type switching Sugar absor.ption in fission yeast, 3481 Cell swelling increases a barium-inhibitable potassium conductance in the Sympathetic innervation basolateral membrane of Necturus small intestine, 3591 Expression of the -3-nerve growth factor gene correlates with the density Sugar nucleotide of sympathetic innervation in effector organs, 7951 Formation of bile acid glucosides by a sugar nucleotide-independent Sympathetic nervous system glucosyltransferase isolated from human liver microsomes, 7036 Adenosine strongly potentiates pressor responses to nicotine in rats, 5599 Sulfate Synapse Identification of a sulfate-bearing molecule associated with HLA class II Asymmetric acetylcholinesterase is assembled in the Golgi apparatus, 479 antigens, 1534 Evidence that the major postsynaptic density protein is a component of a Decrease of tyrosine-O-sulfate-containing proteins found in rat fibroblasts 945 infected with Rous sarcoma virus or Fujinami sarcoma virus, 3695 Ca2+/calmodulin-dependent protein kinase, De novo cellular synthesis of sulfated proteoglycans of the developing Synapsin renal glomerulus in vivo, 7108 A quantitative dot-immunobinding assay for proteins using nitrocellulose Sulfation membrane filters, 1684 Sulfation of lutropin oligosaccharides with a cell-free system, 5320 Synaptic membrane Mechanisms of glycosylation and sulfation in the Golgi apparatus: Spider venoms inhibit L-glutamate binding to brain synaptic membrane Evidence for nucleotide sugar/nucleoside monophosphate and receptors, 5571 nucleotide sulfate/nucleoside monophosphate antiports in the Golgi Synaptic potential apparatus membrane, 7051 Adenosine selectively blocks parallel-fiber-mediated synaptic potentials in Sulfhydryl group rat cerebellar cortex, 6531 Interaction of the 2,6-dimethoxysemiquinone and ascorbyl free radicals Synaptic stimulation with Ehrlich ascites cells: A probe of cell-surface charge, 2088 Synaptic stimulation alters protein phosphorylation in vivo in a single Sulfur-dependent bacteria Aplysia neuron, 3233 Eocytes: A new ribosome structure indicates a kingdom with a close Synaptic vesicle relationship to eukaryotes, 3786 Biochemical evidence that vesicles are the source of the acetylcholine Sunlight released from stimulated PC12 cells, 6535 Fibroblasts from patients with hereditary cutaneous malignant melanoma Synaptosomal membrane are abnormally sensitive to the mutagenic effect of simulated sunlight Reconstitution of a functional synaptosomal membrane possessing the and 4-nitroquinoline 1-oxide, 1179 protein constituents involved in acetylcholine translocation, 277 Supercoiling Synaptosome The free energy of DNA supercoiling is enthalpy-determined, 1312 Serotonin binds specifically and saturably to an actin-like protein isolated Superior cervical g on from rat brain synaptosomes, 959 Partial characterization of the neurotrophic factor for maintenance of Isolation, purification, and reconstitution of the Na' gradient-dependent acetylcholinesterase and butyrylcholinesterase in the preganglionically Ca2' transporter (Na+-Ca + exchanger) from brain synaptic plasma denervated superior cervical ganglion of the cat in vivo, 6539 membranes, 6521 Electrical stimulation increases phosphorylation of tyrosine hydroxylase Syncytia in superior cervical ganglion of rat, 7243 Infection of human endothelial cells by human T-cell leukemia virus type Superior colliculus I, 7591 Activity and the control of ganglion cell death in the rat retina, 5589 Syncytiotrophoblast Superoxide Human placental syncytiotrophoblastic Mr 75,000 polypeptide defined by Isolation of the Escherichia coli iron superoxide dismutase gene: antibodies to a synthetic peptide based on a cloned human endogenous Evidence that intracellular superoxide concentration does not regulate retroviral DNA sequence, 6197 oxygen-dependent synthesis of the manganese superoxide Syncytlum dismutase, 4970 Characterization of a herpes simplex virus type 1 mutant resistant to Detection of superoxide generated by endothelial cells, 7269 benzhydrazone, a selective inhibitor of herpesvirus glycosylation, 2440 Biological Sciences Subject Index Proc. Natl. Acad. Sci. USA 81 (1984) 8133

Syndein The heterogeneity and functional capacities of human thymocyte A structural model of human erythrocyte band 2.1: Alignment of chemical subpopulations, 4912 and functional domains, 4095 T cell antigen-bInding molecule Synechococcus Messenger RNA for an antigen-specific binding molecule from an antigen- Active-site carbamate formation and reaction-intermediate-analog binding specific T-cell hybrid, 1524 by ribulosebisphosphate carboxylase/oxygenase in the absence of its T-ceil clone small subunits, 3660 Sendai virus-specific T-cell clones: Induction of cytolytic T cells by an Synovial fibroblast anti-idiotypic antibody directed against a helper T-cell clone, 2850 Isolation of a collagenase cDNA clone and measurement of changing T cell, cytolytic collagenase mRNA levels during induction of rabbit synovial Malignant growth in the normal host after variant selection in vitro with fibroblasts, 1981 cytolytic T-cell lines, 2186 Synteny T-cell-dependent antigen Cellular homologs of the avian erythroblastosis virus erb-A and erb-B Single-cell studies on hapten-specific B cells: Response to T-cell- genes are syntenic in mouse but asyntenic in man, 4874 dependent antigens, 2479 Synthetic peptide antigen T-cell factor Antibodies of predetermined specificity against chemically synthesized Synergistic effects of antigen and soluble T-cell factors in B-lymphocyte peptides of human interleukin 2, 2176 activation, 5537 Epitope-specific protective immunogenicity of chemically synthesized Acetylcholine receptor-specific suppressive T-cell factor from a 13-, 18-, and 23-residue peptide fragments of streptococcal M retrovirally transformed T-cell line, 7569 protein, 2203 T-cell growth factor Immunity and protection against influenza virus by synthetic peptide See also Interleukin 2 corresponding to antigenic sites of hemagglutinin, 2461 Purification to homogeneity and partial characterization of interleukin 2 Antibodies against a synthetic peptide identify the Epstein-Barr virus- from a human T-cell leukemia, 871 determined nuclear antigen, 4652 T-cell growth factor: Complete nucleotide sequence and organization of Monoclonal antibodies of predefined specificity detect activated ras gene the gene in normal and malignant cells, 1634 expression in human mammary and colon carcinomas, 5227 Human T-cell growth factor: Partial amino acid sequence, cDNA cloning, Human placental syncytiotrophoblastic Mr 75,000 polypeptide defined by and organization and expression in normal and leukemic cells, 2543 antibodies to a synthetic peptide based on a cloned human endogenous Thymosin increases production of T-cell growth factor by normal human retroviral DNA sequence, 6197 peripheral blood lymphocytes, 2882 Detection in vivo of a new gene product (gene III) of cauliflower mosaic Cyclosporin A inhibits T-cell growth factor gene expression at the level of virus, 6608 mRNA transcription, 5214 Identification of the tyrosine protein kinase from LSTRA cells by use of T-cell hybridona site-specific antibodies, 6676 Processing of lysozyme by macrophages: Identification of the Both cholera toxin-induced adenylate cyclase activation and cholera toxin determinant recognized by two T-cell hybridomas, 2489 biological activity are inhibited by antibodies against related synthetic Antigen presentation by murine and human cells to a murine T-cell peptides, 7893 hybridoma: Demonstration of a restriction element associated with a Syntrophism major histocompatibility complex class II determinant(s) shared by Rhizobium free-living nitrogen fixation occurs in specialized nongrowing both species, 7559 cells, 1566 T-cell leukemia Systemic lupus erythematosus Purification to homogeneity and partial characterization of interleukin 2 Pulse labeling of small nuclear ribonucleoproteins in vivo reveals distinct from a human T-cell leukemia, 871 patterns of antigen recognition by human autoimmune antibodies, 3185 Monoclonal integration of human T-cell leukemia provirus in all primary tumors of adult T-cell leukemia suggests causative role of human T-cell T3 leukemia virus in the disease, 2534 Triggering of the T3-Ti antigen-receptor complex results in clonal T-cell T-cell leukemia virus proliferation through an interleukin 2-dependent autocrine Molecular cloning of a unique human T-cell leukemia virus (HTLV- pathway, 1509 IMo), 993 Role of T3 surface molecules in human T-cell activation: T3-dependent Pseudotypes of human T-cell leukemia virus types 1 and 2: Neutralization activation results in an increase in cytoplasmic free calcium, 4169 by patients' sera, 2886 T cell See also T lymphocyte T-cell lYmphokine Immunoprecipitation of cell surface structures of cloned cytotoxic T Antigen-specific helper T-cell clone supernatant is sufficient to induce lymphocytes by clone-specific antisera, 573 both polyclonal proliferation and differentiation of small resting B Functional T cells in athymic nude mice, 886 lymphocytes, 6491 Isolation and characterization of a mouse cDNA clone that expresses T-celi lymphoma mast-cell growth-factor activity in monkey cells, 1070 Rearrangement of a DNA sequence homologous to a cell-virus junction Thymic T cells are driven to expand upon interaction with self-class II fragment in several Moloney murine leukemia virus-induced rat major histocompatibility complex gene products on accessory thymomas, 38 cells, 1221 Isolation and characterization of a stage-specific transforming gene, Tlym- Triggering of the T3-Ti antigen-receptor complex results in clonal T-cell I, from T-cell lymphomas, 2227 proliferation through an interleukin 2-dependent autocrine Purification and chemical characterization of the receptor for interleukin pathway, 1509 2 from activated human T lymphocytes and from a human T-cell Formation of IgE-binding factors by human T-cell hybridomas, 1514 lymphoma cell line, 6481 Isolation and partial characterization of concanavalin A receptors on Leukemia-derived growth factor (non-interleukin-2) produced by murine cloned cytotoxic T lymphocytes, 1519 lymphoma T-cell lines, 7807 Messenger RNA for an antigen-specific binding molecule from an antigen- T-cell receptor specific T-cell hybrid, 1524 Attachment of an anti-receptor antibody to non-target cells renders them Mechanism of T-cell lymphomagenesis: Transformation of growth-factor- susceptible to lysis by a clone of cytotoxic T lymphocytes, 7922 dependent T-lymphoblastoma cells to growth-factor-independent T- T-DNA lymphoma cells, 1742 Crown gall oncogenesis: Evidence that a T-DNA gene from the Antigenic stimulation regulates the level of expression of interleukin 2 Agrobacterium Ti plasmid pTiA6 encodes an enzyme that catalyzes receptor on human T cells, 2172 synthesis of indoleacetic acid, 5071 Thymus-derived lymphocytes and their interactions with macrophages are T-DNA of Agrobacterium tumefaciens encodes an enzyme of cytokinin required for the production of osteoclast-activating factor in the biosynthesis, 5994 mouse, 2181 Nucleotide sequence of the insertion sequence found in the T-DNA Development of a human T-cell hybridoma secreting separate B-cell region of mutant Ti plasmid pTiA66 and distribution of its homologues growth differentiation factors, 2475 in octopine Ti plasmid, 7495 T-cell-mediated cytotoxicity against autologous malignant melanoma: T lymphocyte Analysis with interleukin 2-dependent T-cell cultures, 3511 See also T cell Chronic treatment with rabbit anti-mouse A-chain antibody alters the Human T-lymphocyte subset specificity of the regulatory effects of characteristic immunoglobulin heavy-chain restriction of murine leukotriene B4, 3501 suppressor T-cell factors, 3846 Internal complementarities in the immune system: Regulation of the Transformation of owl monkey T cells in vitro with Herpesvirus expression of helper T-cell idiotypes, 4520 saimiri, 4563 Purification and chemical characterization of the receptor for interleukin Immunodeficiency with defective T-cell response to interleukin 1, 4945 2 from activated human T lymphocytes and from a human T-cell Regulation of T-cell function by antibodies: Enhancement of the response lymphoma cell line, 6481 of human T-cell clones to hepatitis B surface antigen by antigen- Monocytes are required to trigger Ca2+ uptake in the proliferative specific monoclonal antibodies, 6846 response of human T lymphocytes to Staphylococcus aureus protein T-cell activation A, 6827 Role of T3 surface molecules in human T-cell activation: T3-dependent Isolation of the gene encoding the human T-lymphocyte differentiation activation results in an increase in cytoplasmic free calcium, 4169 antigen Leu-2 (T8) by gene transfer and cDNA subtraction, 7688 Antigen conformation determines processing requirements for T-cell Tail spike activation, 6831 Single amino acid substitutions influencing the folding pathway of the Calcium dependency of antigen-specific (T3-Ti) and alternative (T11) phage P22 tail spike endorhamnosidase, 6584 pathways of human T-cell activation, 6836 Tandem copies T-ceil antigen Multiple joined genes prevent product degradation in Escherichia Purification and NH2-terminal amino acid sequencing of the (3 subunit of coli, 4627 a human T-cell antigen receptor, 3851 8134 Biological Sciences Subject Index Proc. NatL Acad Sci. USA 81 (1984)

Tandem repeat Molecular cloning of human terminal deoxynucleotidyltransferase, 4363 Clustered genes for human U2 RNA, 3811 Cloning of terminal transferase cDNA by antibody screening, 5836 Tangier disease Terminal protein Nucleotide sequence and the encoded amino acids of human Purification in a functional form of the terminal protein of Bacillus apolipoprotein A-I mRNA, 66 subtilis phage 4i29, 1639 Target polypeptide Replication of bacteriophage 429 DNA replication in vitro: The roles of Target polypeptide of a carcinogen is associated with normal mitosis and terminal protein and DNA polymerase, 5374 carcinogen-induced hyperplasias in adult hepatocytes, 6738 Terminal transferase Target theory Molecular cloning of human terminal deoxynucleotidyltransferase, 4363 Radiation inactivation of oligomeric enzyme systems: Theoretical Termination considerations, 150 A precise termination site in the mouse pmaior-globin transcription unit Functional molecular weight of the lac carrier protein from Escherichia (Correction), 2274 coli as studied by radiation inactivation analysis, 1021 Formation of termination-resistant transcription complex at phage X nut "TATA" box locus: Effects of altered translation and a ribosomal mutation, 3612 P-Thalassemia in American Blacks: Novel mutations in the "TATA" box Synthesis of the templates for influenza virion RNA replication in and an acceptor splice site, 1154 vitro, 4682 Contact points between transcription machinery and the fibroin gene Pausing and premature termination of human RNA polymerase II during promoter deduced by functional tests of single-base substitution transcription of adenovirus in vivo and in vitro, 5931 mutants, 1394 nusB: A protein factor necessary for transcription aptitermination in vitro Structure and expression of a pea nuclear gene encoding a chlorophyll by phage X N gene product, 6305 a/b-binding polypeptide, 2960 Antitermination of transcription from an Escherichia coli ribosomal RNA (3-Thalassemia in American Blacks: Novel mutations in the "TATA" box promoter, 6789 and an acceptor splice site (Correction), 3605 Identification and characterization of a new transcriptional termination Regulation of polyomavirus transcription by large tumor antigen, 6919 factor from Escherichia coli, 7373 Upstream activation sites of the CYCI gene of Saccharomyces cerevisiae Termite are active when inverted but not when placed downstream of the Soldier formation regulated by a primer pheromone from the soldier "TATA box", 7860 frontal gland in a higher termite, Nasutitermes lujae, 7665 tau Testicular feminization tau, a repeated DNA sequence in yeast, 2965 Androgen induction of ornithine decarboxylase mRNA in mouse kidney 2' factor as studied by complementary DNA, 731 Identification and characterization of a new transcriptional termination Testis factor from Escherichia coli, 7373 Characterization of a membrane antigen from rabbit testis and sperm x protein isolated by using monoclonal antibodies and effect of its antiserum on Axonal transport of a subclass of r proteins: Evidence for the regional fertility, 857 differentiation of microtubules in neurons, 1570 The mononuclear phagocyte system of the mouse defined by Tautomer immunohistochemical localization of antigen F4/80: Macrophages of Proton-transfer spectroscopy of 3-hydroxyflavone in an isolated-site endocrine organs, 4174 crystal matrix, 3375 Expression of pro-opiomelanocortin-like gene in the testis and Taxol epididymis, 5672 Antagonism by taxol of effects of microtubule-disrupting agents on Dissociation between testicular organogenesis and endocrine lymphocyte cAMP metabolism and cell function, 34% cytodifferentiation of Sertoli cells, 7831 Relationships between the structures of taxol and baccatine III Testosterone derivatives and their in vitro action on the disassembly of mammalian Simultaneous administration of pure antiandrogens, a combination brain and Physarum amoebal microtubules, 4090 necessary for the use of luteinizing hormone-releasing hormone Taxon longevity agonists in the treatment of prostate cancer, 3861 Repeatability of taxon longevity in successive foraminifera radiations and Seasonal aggression independent of seasonal testosterone in wood a theory of random appearance and extinction, 5478 rats, 5255 Tay-Sachs diseaae Tethered enzyme cDNA clone for the a-chain of human j3-hexosaminidase: Deficiency of Catalytic consequences of oligomeric organization: Kinetic evidence for a-chain mRNA in Ashkenazi Tay-Sachs fibroblasts, 5394 "tethered" acto-heavy mdromyosin at low ATP concentrations, 5345 Technetium 2,3,7,8-Tetrachlorodibenzop-dioxin 9'Tc-labeled nucleotides as tumor-seeking radiodiagnostic agents, 918 Effects of in vivo-administered 2,3,7,8-tetrachlorodibenzo-p-dioxin on Telomere receptor binding of epidermal growth factor in the hepatic plasma Elaboration of telomeres in yeast: Recognition and modification of membrane of rat, guinea pig, mouse, and hamster, 7407 termini from Oxytricha macronuclear DNA, 1475 12-0-Tetradecanoylphorbol 13-acetate mu-2: Mutator gene in Drosophila that potentiates the induction of See Phorbol 12-myristate 13-acetate terminal deficiencies, 6090 Tetrahydrofolate Temperature Role of carbon monoxide dehydrogenase in the autotrophic pathway used Regulation of bacterial DNA supercoiling: Plasmid linking numbers vary by acetogenic bacteria, 6261 with growth temperature, 4046 Tetrahydromethanopterin Temperature effect Formaldehyde activation factor, tetrahydromethanopterin, a coenzyme of Effects of temperature on the degradation of proteins in rabbit methanogenesis, 1976 reticulocyte lysates and after injection into HeLa cells, 90 Tetrahymena Temperature-sensitive mutant Specific DNA rearrangements in synchronously developing nuclei of Partial purification and characterization of the mRNA complementing a Tetrahymena, 7383 temperature-sensitive S-phase cell cycle mutation, 2393 Tetrapyrrole Cell-cycle-specific cDNAs from mammalian cells temperature sensitive Mn2` and Co2+ toxicity in chlorophyll biosynthesis, 476 for growth, 6004 Tetrodotoxin Specific protein modifications are altered in a temperature-sensitive Electrical activity and cytosolic calcium regulate levels of tetrodotoxin- Drosophila developmental mutant, 6422 sensitive sodium channels in cultured rat muscle cells, 262 Single amino acid substitutions influencing the folding pathway of the Reconstitution of neurotoxin-modulated ion transport by the voltage- phage P22 tail spike endorhamnosidase, 6584 regulated sodium channel isolated from the electroplax of Template Electrophorus electricus, 1239 Template requirements for initiation of phage 429 DNA replication in Activity and the control of ganglion cell death in the rat retina, 5589 vitro, 80 Single-channel properties of the reconstituted voltage-regulated Na Template requirements for the initiation of adenovirus DNA channel isolated from the electroplax of Electrophorus electricus, 5594 replication, 100 Thalamus Synthesis of the templates for influenza virion RNA replication in Function of the thalarnic reticular complex: The searchlight vitro, 4682 hypothesis, 4586 Temporal lobe syndrome Thalassemia Hippocampal denervation causes rapid forgetting of olfactory information f-Thalassemia in Chinese: Use of in vivo RNA analysis and in rats, 5885 oligonucleotide hybridization in systematic characterization of Teratocarcinoma molecular defects, 2821 Variations in DNA methylation during mouse cell differentiation in vivo ty-Thalassemia and in vitro, 2275 Human embryonic C-globin chains in adult patients with a- Teratocarcinoma cell thalassemias, 6188 Induction of murine teratocarcinoma cell differentiation by suppression of 1-Thalassemia poly(ADP-ribose) synthesis, 7132 ,-Thalassemia in American Blacks: Novel mutations in the "TATA" box Teratogen and an acceptor splice site, 1154 Teratogens induce a subset of small heat shock proteins in Drosophila -3-Thalassemia in American Blacks: Novel mutations in the "TATA" box primary embryonic cell cultures, 4075 and an acceptor splice site (Correction), 3605 Teratogenesls Theiler's murine encephalomyelitis virus Glucocorticoid-induced phospholipase A2-inhibitory proteins mediate Simultaneous in situ detection of viral RNA and antigens, 5445 glucocorticoid teratogenicity in vitro, 1140 Theoretical biology Terminal deoxynucleotidyltransferase Outline of a theory of cellular heterogeneity, 5126 Hematopoietic cell transformation by a murine recombinant retrovirus containing the src gene of Rous sarcoma virus, 2374 Biological Sciences Subject Index Proc. Nati. Acad. Sci USA 81 (1984) 8135

Thermoluminescence Thymosin increases production of T-cell growth factor by normal human Charge accumulation and photochemistry in leaves stulied by peripheral blood lymphocytes, 2882 thermoluminescence and delayed light emission, 1107 Distribution of prothymosid a in-rat tissues (Correction), 3605 Thermolysin Thymus Biologic activity in a fragment of recombinant human interferon a, 1045 Tunctional T cells in athymic nude mice, 886 Thin filament F-actin is intermolecularly crosslinked by N,N'-p-phenylenedimaleimide Thyrotropin controls transcription of the thyroglobulin gene, 5941 through lysine-191 and cysteine-374, 6599 Thyroid cancer 4-Thlouridine Chromosome 20 deletion in human multiple endocrine neoplasia types 2A Molecular cloning of hormone-responsive genes from the yeast and 2B: A double-blind study, 2525 Saccharomyces cerevisiae, 1144 Thyroid hormone Thrombin Rapid induction of a specific nuclear mRNA precursor by thyroid Human endothelial cells in culture produce platelet-activating factor hormone, 4687 (1-alkyl-2-acetyl-sn-glycero-3-phosphocholine) when stimulated with Thyrotropin thrombin, 3534 Assignment of the genes for the a and f subunits of thyrotropin to Thrombophlebitis dferent mouse chromosomes, 517 Antithrombin III Toyama: Replacement of arginine47 by cysteine in Thyrotropin controls transcription of the thyroglobulin gene, 5941 hereditary abnormal antithrombin III that lacks heparin-binding Thyrotropin-rqleasing hormone ability, 289 Glycine-directed peptidp amidation: Presence in rat brain of two enzymes Thrombosis that convert p-Glu-His-Pro-Gly-OH into p-Glu-His-Pro-NH2 Activation of factor IX bound to cultured bovine aortic endothelial (thyrotropin-releasing hormone), 3228 cells, 913 Solubilization and characterization of thyrotropin-releasing hormone Thy-i glycoprotein receptors from rat brain, 4227 Expression of the Thy-1 glycoprotein gene by DNA-mediated gene Thyrotropin-releasing hormone stimulates GTP hydrolysis by membranes transfer, 5532 from GH4C, rat pituitary tumor cells, 6183' Thy-1.2 antigen Thyrroxne Gene transfer in lymphoid cells: Expression of the Thy-1.2 antigen by Characterization of genomic clones specifying rabbit a- and (-ventricular Thy-1.1 BW5147 lymphoma cells transfected with unfractionated myosin heavy chains, 3044 cellular DNA, 7176 Ti antigen Thylakoid membrane Triggering of the T3-Ti antigen-receptor complex results in clonal T-cell Some plant leaves have orientation-dependent EPR and NMR proliferation through an interleukin 2-dependent autocrine spectra, 748 pathway, 1509 NMR study of chloride ion interactions with thylakoid membranes, 3713 Ti plasmid Nucleotide sequence of the tms genes of the pTiA6NC octopine Ti Thymindi"TJlpynidamole inhibits reversion by thymidine of methotrexate effect and plasmid: Two gene products involved in plant tumorigenesis, 1728 increases drug uptake in Sarcoma 180 cells, 3200 Identification of a cloned cytokinin biosynthetic gene, 4776 Kinetics of thymidine incorporation into detergent-soluble DNA of mouse Crown gall oncogenesis: Evidence that a T-DNA gene from the lymphocytes, 7056 Agrobacterium Ti plasmid pTiA6 encodes an enzyme that catalyzes Thymidine glycol synthesis of indoleacetic acid, 5071 Thymine glycol and thymidine glycol in human and rat urine: A possible T-DNA of A'robacterium tumefaciens encodes an enzyme of cytokinin assay for oxidative DNA damage, 5633 biosynthesis, 5994 Thymidine kinase Nucleotide sequence of the insertion sequence found in the T-DNA Mapping of the late promoter of simian virus 40, 23 region of mutant Ti plasmid pTiA66 and distribution of its homologues A pattern of partially homologous recombination in mouse L cells, 206 in octopine Ti plasmid, 7495 Direct isolation of the functional human thymidine kinase gene with a Time series cosmid shuttle vector, 414 Periodicity of extinctions in the geologic past, 801 Insulin-induced reactivation of an inactive herpes simplex thymidine Tissue culture kinase gene, 838 Monitoring fibroblast behavior in tissue culture with an applied electric Separation of sequences defining basal expression from those conferring field, 3761 a gene recognition within the regulatory domains of herpes simplex Titin virus 1 a genes, 4065 Titin is an extraordinarily long, flexible, and slender myofibrillar Cell-specified expression of a selectable hybrid gene, 4657 protein, 3685 Yeast gene CDC8 encodes thymidylate kinase and is complemented by TL region herpes thymidine kinase gene TK, 5821 Murine leukemia virus sequences are encoded in the murine major A 12-base-pair DNA motif that is repeated several times in histocompatibility complex, 1804 metallothionein gene promoters confers metal regulation to a Tobacco heterologous gene, 7318 Organ-specific nuclear RNAs in tobacco, 2801 Thymidine nucleotidase Tobacco mosaic virus Identification of thymidine nucleotidase and deoxyribonucleotidase Chloroplast DNA transcripts are encapsidated by tobacco mosaic virus activities among normal isozymes of 5'-nucleotidase in human coat protein, 1719 erythrocytes, 588 Striking similarities in amino acid sequence among nonstructural proteins Thymidylate kinase encoded by RNA viruses that have dissimilar genomic Yeast gene CDC8 encodes thymidylate kinase and is complemented by organization, 4358 herpes thymidine kinase gene TK, 5821 Radial distributions of density within macromolecular complexes Thymidylate synthase determined from dark-field electron micrographs, 6363 Intervening sequence in the thymidylate synthase gene of bacteriophage Togavirus T4, 3049 An evolutionary tree relating eight alphaviruses, based on amino-terminal Thymine glycol sequences of their glycoproteins, 4702 Thymine glycol and thymidine glycol in human and rat urine: A possible TOL plasmid assay for oxidative DNA damage, 5633 Nucleotide sequence surrounding transcription initiation site of xyLABC Thymineless death operon on TOL plasmid of Pseudomonas putida, 1688 Accumulation of DNA strand breaks and methotrexate cytotoxicity, 5694 Tolerance Thymocyte Cytotoxic T-cell precursors revealed in neonatally tolerant mice, 220 Phosphorylation at a tyrosine residue of lipomodulin in mitogen- Opioid receptor reserve in normal and morphine-tolerant guinea pig ileum stimulated murine thymocytes, 4717 myenteric plexus, 7253 The heterogeneity and functional capacities of human thymocyte Tomato subpopulations, 4912 Wound signals in plants: A systemic plant wound signal alters plasma Chemical reduction of oxidized human lymphocytes inhibits interleukin 2 membrane integrity, 3737 production but not induction of interleukin 2 responsiveness, 5209 Tomography reconstruction kernel Thymoma Sharpening radiographs, 5237 Rearrangement of a DNA sequence homologous to a cell-virus junction Topoisomer fragment in several Moloney murine leukemia virus-induced rat A simple topological method for describing stereoisomers of DNA thymomas, 38 catenanes and knots, 3322 Thymopentin Topoisomerase Contrasting biological activities of thymopoietin and splenin, two closely The free energy of DNA supercoiling is enthalpy-determined, 1312 related polypeptide products of thymus and spleen, 2847 Mechanism of antitumor drug action: Poisoning of mammalian DNA Thymopoletin topoisomerase II on DNA by 4'-(9-acridinylamino)methanesulfon-m- Contrasting biological activities of thymopoietin and splenin, two closely anisidide, 1361 related polypeptide products of thymus and spleen, 2847 DNA topoisomerase II mutant of Saccharomyces cerevisiae: Thymosin Topoisomerase II is required for segregation of daughter molecules at Prothymosin a: Isolation and properties of the major immunoreactive the termination of DNA replication, 2616 form of thymosin a, in rat thymus, 1008 Generation of deletions in pneumococcal mal genes cloned in Bacillus Distribution of prothymosin a in rat tissues, 1391 subtilis, 5189 Cloning and sequence analysis of cDNA from rat spleen thymosin A protein kinase activity tightly associated with Drosophila type II DNA (34, 2295 topoisomerase, 6938 Drosophila DNA topoisomerase I is associated with transcriptionally active regions of the genome, 6958 8136 Biological Sciences Subject Index Proc. NatL. Acad. Sci. USA 81 (1984)

Torpedo Accurate initiation of human e-globin RNA synthesis by Escherichia coli Molecular weight and structural nonequivalence of the mature a subunits RNA polymerase in isolated nuclei of K562 erythroleukemia cells, 4051 of Torpedo californica acetylcholine receptor, 2631 Single gene for the large subunit of ribulosebisphosphate carboxylase in Dimeric structure of single chloride channels from Torpedo maize yields two differentially regulated mRNAs, 4060 electroplax, 2772 Glucocorticoid-mediated induction of a1-acid glycoprotein: Evidence for Different channel properties of Torpedo acetylcholine receptor monomers hormone-regulated RNA processing, 4241 and dimers reconstituted in planar membranes, 6222 Individual products of the adenovirus 12S and 13S Ela mRNAs stimulate Creatine kinase protein sequence encoded by a cDNA made from viral Ella and EIII expression at the transcriptional level, 4381 Torpedo californica electric organ mRNA, 7007 Synthesis of the templates for influenza virion RNA replication in Complete nucleotide sequence of Torpedo marmorata mRNA coding for vitro, 4682 the 43,000-dalton v2 protein: Muscle-specific creatine kinase, 7313 Defining a bacteriophage T4 late promoter: Bacteriophage T4 gene 55 A noncholinergic site-directed monoclonal antibody can impair agonist- protein suffices for directing late promoter recognition, 5101 induced ion flux in Torpedo californica acetylcholine receptor, 7999 Cyclosporin A inhibits T-cell growth factor gene expression at the level of Totipotent hematopoletic stem cell mRNA transcription, 5214 Monoclonal dernvation of mouse myeloid and lymphoid lineages from Distinctive sequence organization and functional programming of an Alu totipotent hematopoietic stem cells experimentally engrafted in fetal repeat promoter, 5291 hosts, 7835 Inducible transcription and puffing in Drosophila melanogaster Toxicity testing transformed with hsp7O-phage X hybrid heat shock genes, 5509 A mutagen-testing assay based on heterogeneity in diameter and In vitro transcription of a silkworm 5S RNA gene requires an upstream integrated optical density of mammalian cell colonies, 2112 signal, 5519 Toxin Isolation of an active transcription initiation complex from HeLa cell-free Toxin-antitoxin selection for isolating somatic cell fusion products extract, 5916 between any cell types, 7822 Pausing and premature termination of human RNA polymerase II during transcription of adenovirus in vivo and in vitro, 5931 Toxin secretion Thyrotropin controls transcription of the thyroglobulin gene, 5941 Mechanism of toxin secretion by Vibrio cholerae investigated in strains Cotranscription of genes encoding the small and large subunits of harboring plasmids that encode heat-labile enterotoxins of Escherichia ribulose-1,5-bisphosphate carboxylase in the cyanobacterium Anabaena coli, 7752 7120, 5961 Toxoplasma Human T-cell leukemia virus (HTLV-I) transcripts in fresh and cultured Interferon y blocks the growth of Toxoplasma gondii in human fibroblasts cells of patients with adult T-cell leukemia, 6207 by inducing the host cells to degrade tryptophan, 908 Proximal and distal domains that control in vitro transcription of the Trace element adenovirus IVa2 gene, 6290 Effect of selenium deficiency on cuticle integrity in the Cladocera nusB: A protein factor necessary for transcription antitermination in vitro (Crustacea), 3433 by phage X N gene product, 6305 Trachea Activation of pS2 gene transcription is a primary response to estrogen in Monoclonal antibodies as probes for unique antigens in secretory cells of the human breast cancer cell line MCF-7, 6344 mixed exocrine organs, 4419 Transcriptional activation of the rat liver tyrosine aminotransferase gene Leukotriene E4-induced airway hyperresponsiveness of guinea pig by cAMP, 6637 tracheal smooth muscle to histamine and evidence for three separate A viable simian virus 40 variant that carries a newly generated sequence sulfidopeptide leukotriene receptors, 4922 reiteration in place of the normal duplicated enhancer element, 6652 Transcription A purified fraction containing RNA polymerase I that can accurately Determination of the promoter region of mouse ribosomal RNA gene by transcribe rat ribosomal RNA gene, 6672 an in vitro transcription system, 299 Transcriptional induction of two genes in human cells by (3 Stimulation of in vitro transcription from heterologous promoters by the interferon, 6733 simian virus 40 enhancer, 308 Antitermination of transcription from an Escherichia coli ribosomal RNA On the mechanism of nucleolar dominance in mouse-human somatic cell promoter, 6789 hybrids, 484 Regulation of polyomavirus transcription by large tumor antigen, 6919 Mutational analysis of a regulatory region in bacteriophage X that has Drosophila DNA topoisomerase I is associated with transcriptionally overlapping signals for the initiation of transcription and active regions of the genome, 6958 translation, 555 Functions of purified ElA protein microinjected into mammalian Transcripts of human HLA gene fragments lacking the 5'-terminal region cells, 6988 in transfected mouse cells, 649 Multicomponent RNA plant virus infection derived from cloned viral Promoter-regulatory region of the major immediate early gene of human cDNA, 7066 cytomegalovirus, 659 Identification and characterization of a new transcriptional termination Glucocorticoid inhibition of initiation of transcription of the DNA factor from Escherichia coli, 7373 encoding rRNA (rDNA) in lymphosarcoma P1798 cells, 718 Duplicated heavy metal control sequences of the mouse metallothionein-I Generation of a TnS promoter probe and its use in the study of gene gene, 7392 expression in Caulobacter crescentus, 1035 Specific stimulation of actin gene transcription by epidermal growth Nucleotide sequence analysis of the long terminal repeat of human T-cell factor and cycloheximide, 7476 leukemia virus type II, 1079 Molecular cloning and sequence determination of rat preproenkephalin Demonstration of transcriptional regulation of specific genes by cDNA: Sensitive probe for studying transcriptional changes in rat phytochrome action, 1112 tissues, 7651 Molecular cloning of hormone-responsive genes from the yeast a-Amanitin-insensitive transcription of mouse ,3mair-globin 5'-flanking Saccharomyces cerevisiae, 1144 and structural gene sequences correlates with mRNA expression, 7782 Adenovirus early region 1A protein activates transcription of a nonviral Transcription complex gene introduced into mammalian cells by infection or transfection, 1193 Formation of termination-resistant transcription complex at phage X nut Contact points between transcription machinery and the fibroin gene locus: Effects of altered translation and a ribosomal mutation, 3612 promoter deduced by functional tests of single-base substitution Transcription, coupled mutants, 1394 Efficient coupled transcription and mRNA splicing in vitro using plasmids Natural fibroin genes purified without using cloning procedures from derived from early region 3 of adenovirus 2 and a nondefective fibroin-producing and -nonproducing tissues reveal indistinguishable adenovirus-simian virus 40 hybrid, 2679 structure and function, 1644 Transcription, directed Stimulation of simian virus 40 late gene expression by simian virus 40 Cloning and expression of the gene for bacteriophage T7 RNA tumor antigen, 2040 polymerase, 2035 In vitro mutagenesis and transcriptional analysis of a mouse ribosomal Transcription factor 1 promoter element, 2137 Sequence of the bacteriophage SP01 gene coding for transcription factor Potential basis for regulation of the coordinately expressed fibrinogen a viral of the bacterial II genes: Homology in the 5' flanking regions, 2313 1, homologue type DNA-binding Temporal expression of late histone messenger RNA in the sea urchin proteins, 7031 Lytechinus pictus, 2411 Transcription initiation Determination of the promoter region of mouse ribosomal RNA gene by Nucleotide sequence surrounding transcription initiation site of xyl4BC an in vitro transcription system (Correction), 2587 operon on TOL plasmid of Pseudomonas putida, 1688 Transcription of human histone genes in extracts from synchronized Kinetic analysis of mutations affecting the cI activation site at the PRE HeLa cells, 2713 promoter of bacteriophage X, 6432 Polypeptide hormone regulation of gene transcription: Specific 5' Transcription termination genomic sequences are required for epidermal growth factor and A precise termination site in the mouse IBmaio-globin transcription unit phorbol ester regulation of prolactin gene expression, 2975 (Correction), 2274 Transcripts of human HLA gene fragments lacking the 5'-terminal region Transcription unit in transfected mouse cells (Correction), 3243 tRNAnet gene in the leader region of the nusA operon in Escherichia Selective expression of a plasmid cat gene at a late stage of Bacillus coli, 409 subtilis sporulation, 3457 Transcriptional activation Synthesis of cholera toxin is positively regulated at the transcriptional Isolation and characterization of the rat tyrosine aminotransferase level by toxR, 3471 1346 Alternative modes of enkephalin biosynthesis regulation by reserpine and gene, cyclic AMP in cultured chromaffin cells, 3949 Transducer Tandem promoters preceding the gene for the Ml RNA component of Structure of the Trg protein: Homologies with and differences from other Escherichia coli ribonuclease P. 3959 sensory transducers of Escherichia coli, 3287 Inhibition of protein synthesis stimulates the transcription of human Transducin interferon genes in Chinese hamster ovary cells, 3964 Isolation and characterization of a cDNA clone for the y subunit of bovine retinal transducin, 6948 Biological Sciences Subject Index Proc. Natl. Acad. Sci. USA 81 (1984) 8137

Transduction Mechanism of activation of an N-ras oncogene of SW-1271 human lung Mechanoelectrical transducer has discrete conductances in the chick carcinoma cells, 3670 vestibular hair cell, 1888 Analysis of the transforming potential of the human H-ras gene by Cell-specified expression of a selectable hybrid gene, 4657 random mutagenesis, 4008 Use of adeno-associated virus as a mammalian DNA cloning vector: The chromosome 14 breakpoint in neoplastic B cells with the t(11;14) Transduction of neomycin resistance into mammalian tissue culture translocation involves the immunoglobulin heavy chain locus, 4144 cells, 6466 Expression of an 86-kilodalton glycoprotein in an idiopathic mammary Construction of a retrovirus capable of transducing and expressing genes adenocarcinoma of a BALB/c mouse, 4159 in multipotential embryonic cells, 7137 Identification and mapping of polypeptides encoded by the P3HR-1 strain Transfection of Epstein-Barr virus, 4183 Expression of an immunoglobulin heavy chain gene transfected into Avian myeloblastosis virus and E26 virus oncogene products are nuclear lymphocytes, 1292 proteins, 4265 Cloned Drosophila alcohol dehydrogenase genes are correctly expressed Differences in keratin synthesis between normal epithelial cells and after transfection into Drosophila cells in culture, 1701 squamous cell carcinomas are mediated by vitamin A, 4280 Recombination of transfected DNAs in vertebrate cells in culture, 3476 Rous sarcoma virus variants that carry the cellular src gene instead of the Expression of a nuclear and a cytoplasmic Epstein-Barr virus early viral src gene cannot transform chicken embryo fibroblasts, 4424 antigen after DNA transfer: Cooperation of two distant parts of the Transformation-associated proteins in murine B-cell lymphomas that are genome for expression of the cytoplasmic antigen, 4568 distinct from Abelson virus gene products, 4434 Eukaryotic chromosome transfer: Linkage of the murine major Transformation of owl monkey T cells in vitro with Herpesvirus histocompatibility complex to an inserted dominant selectable saimiri, 4563 marker, 4879 Small fragments of herpesvirus DNA with transforming activity contain Stable transfer and expression of exogenous human globin genes in insertion sequence-like structures, 4736 human erythroleukemia (K562) cells, 5315 Molecular cloning and the total nucleotide sequence of the human c-Ha- A position 12-activated H-ras oncogene in all HS578T mammary ras-1 gene activated in a melanoma from a Japanese patient, 4771 carcinosarcoma cells but not normal mammary cells of the same No evidence for differences in the Epstein-Barr virus genome carried in patient, 5384 Burkitt lymphoma cells and nonmalignant lymphoblastoid cells from Expression of the Thy-1 glycoprotein gene by DNA-mediated gene the same patients, 4930 transfer, 5532 Constitutive production of human interferons by mouse cells with bovine Enhancer-dependent expression of human K immunoglobulin genes papillomavirus as a vector, 5086 introduced into mouse pre-B lymphocytes by electroporation, 7161 Regulation of glutathione transferase and DT-diaphorase mRNAs in Gene transfer in lymphoid cells: Expression of the Thy-1.2 antigen by persistent hepatocyte nodules during chemical Thy-1.1 BW5147 lymphoma cells transfected with unfractionated hepatocarcinogenesis, 5091 cellular DNA, 7176 Early origin and pervasiveness of cellular heterogeneity in some Direct transfection of viral and plasmid DNA into the liver or spleen of malignant transformations, 5121 mice, 7529 Cytoskeletal involvement in cAMP-induced sensitization of chromatin to Recognition of HLA-A2 and -B7 antigens by cloned cytotoxic T nuclease digestion in transformed Chinese hamster ovary K1 cells, 5145 lymphocytes after gene transfer into human and monkey, but not Hyperrecombination at a specific DNA sequence in pneumococcal mouse, cells, 7549 transformation, 5184 Transfer RNA Expression of normal and transforming H-ras genes in Escherichia coli See tRNA and purification of their encoded p21 proteins, 5305 Transferrin Neoplastic human fibroblast proteins are related to epidermal growth Morphologic characterization of the pathway of transferrin endocytosis factor precursor, 5360 and recycling in human KB cells, 175 A position 12-activated H-ras oncogene in all HS578T mammary Human transferrin: cDNA characterization and chromosomal carcinosarcoma cells but not normal mammary cells of the same localization, 2752 patient, 5384 Occupancy of the iron binding sites of human transferrin, 4326 obl7 cells transformed by the middle-T-only gene of polyoma virus Binding of transferrin to the core protein of fibroblast proteoheparan differentiate in vitro and in vivo into adipose cells, 5440 sulfate, 5657 Inducible transcription and puffing in Drosophila melanogaster transformed with hsp7O-phage X hybrid heat shock genes, 5509 Transferrin receptor Transformation properties of type 5 adenovirus mutants that differentially Association of phorbol ester-induced hyperphosphorylation and reversible express the ElA gene products, 5734 regulation of transferrin membrane receptors in HL60 cells, 2016 Biological activities of v-myc and rearranged c-myc oncogenes in rat Rapid internalization of the transferrin receptor in K562 cells is triggered fibroblast cells in culture, 5758 by ligand binding or treatment with a phorbol ester, 3005 Antibodies to two defined regions of the transforming protein pp6&src Binding of transferrin to the core protein of fibroblast proteoheparan interact specifically with the epidermal growth factor receptor kinase sulfate, 5657 system, 5911 Epidermal growth factor rapidly induces a redistribution of transferrin Human T-cell leukemia virus (HTLV-I) transcripts in fresh and cultured receptor pools in human fibroblasts, 7456 cells of patients with adult T-cell leukemia, 6207 Transformation Quantitative assay for albumin-producing liver cells after simian virus 40 Isolation of transforming sequences of two human lung carcinomas: transformation of rat hepatocytes maintained in chemically defined Structural and functional analysis of the activated c-K-ras medium, 6378 oncogenes, 71 Phorbol ester, serum, and Rous sarcoma virus transforming gene product Inhibition of malignant transformation in vitro by inhibitors of poly(ADP- induce similar phosphorylations of ribosomal protein S6, 6408 ribose) synthesis, 243 Occurrence of caldesmon (a calmodulin-binding protein) in cultured cells: Frequent generation of nonrescuable reorganized Moloney murine Comparison of normal and transformed cells (Correction), 6548 sarcoma viral genomes, 294 Specific binding to cultured cells of 125I-labeled type (3 transforming Transformation by polyoma virus is drastically reduced by substitution of growth factor from human platelets, 6757 phenylalanine for tyrosine at residue 315 of middle-size tumor Extreme instability of myc mRNA in normal and transformed human antigen, 679 cells, 7046 The membrane glycoprotein encoded by the retroviral oncogene v-erb-B Overexpression of the c-src protein does not induce transformation of is structurally related to tyrosine-specific protein kinases, 704 NIH 3T3 cells, 7071 Alteration of neural cell adhesion molecule (N-CAM) expression after src- andfps-containing avian sarcoma viruses transform chicken erythroid neuronal cell transformation by Rous sarcoma virus, 969 cells, 7122 Transformation of Aspergillus nidulans by using a trpC plasmid, 1470 Gene transfer in lymphoid cells: Expression of the Thy-1.2 antigen by Mechanism of T-cell lymphomagenesis: Transformation of growth-factor- Thy-1.1 BW5147 lymphoma cells transfected with unfractionated dependent T-lymphoblastoma cells to growth-factor-independent T- cellular DNA, 7176 lymphoma cells, 1742 A membrane protein encoded by Epstein-Barr virus in latent growth- Active oxygen acts as a promoter of transformation in mouse embryo transforming infection, 7207 C3H/10T½/z/C18 fibroblasts, 2085 An immunological method for detecting gene expression in yeast Evidence that the Rous sarcoma virus transforming gene product colonies, 7426 phosphorylates phosphatidylinositol and diacylglycerol, 2117 Interspecific DNA transformation in Drosophila, 7515 Isolation and characterization of a stage-specific transforming gene, Tlym- Mouse c-mos oncogene activation is prevented by upstream I, from T-cell lymphomas, 2227 sequences, 7817 Transformation by Rous sarcoma virus prevents acetylcholine receptor Identification of a second transforming region in bovine papillomavirus clustering on cultured chicken muscle fibers, 2265 DNA, 7880 Hematopoietic cell transformation by a murine recombinant retrovirus containing the src gene of Rous sarcoma virus, 2374 Transforming growth factor Production of platelet-derived growth factor-like molecules and reduced Neuroblastoma cells produce transforming growth factors during expression of platelet-derived growth factor receptors accompany exponential growth in a defined hormone-free medium, 4085 transformation by a wide spectrum of agents, 2396 Specific binding to cultured cells of 125I-labeled type (8 transforming Transforming protein of avian sarcoma virus UR2 is associated with growth factor from human platelets, 6757 phosphatidylinositol kinase activity: Possible role in Vaccinia virus 19-kilodalton protein: Relationship to several mammalian tumorigenesis, 2728 proteins, including two growth factors, 7363 Expression of the transformation-sensitive protein "cyclin" in normal A placental polypeptide activator of a membranous protein kinase and its human epidermal basal cells and simian virus 40-transformed relation to histone 1, 7388 keratinocytes, 3128 Transforming protein Occurrence of caldesmon (a calmodulin-binding protein) in cultured cells: Specific covalent binding of platelet-derived growth factor to human Comparison of normal and transformed cells, 3133 plasma a2-macroglobulin, 342 In vitro transformation of mesenchymal cells derived from embryonic Specific covalent binding of platelet-derived growth factor to human muscle into cartilage in response to extracellular matrix components of plasma a2-macroglobulin (Correction), 2586 bone, 3419 8138 Biological Sciences Subject Index Proc. NatL. Acad. Sci. USA 81 (1984)

Antibodies to two defined regions of the transforming protein pp605rc Transposable element DIRS-1 interact specifically with the epidermal growth factor receptor kinase Dictyostelium transposable element DIRS-1 has 350-base-pair inverted system, 5911 terminal repeats that contain a heat shock promoter, 2660 Transglutaminase Transposition Keratolinin: The soluble substrate of epidermal transglutaminase from Cleavage of the site-specific recombination protein )8 resolvase: The human and bovine tissue, 238 smaller of two fragments binds DNA specifically, 2001 Lens transglutaminase selects specific 8-crystallin sequences as Essential sites at transposon TnJO termini, 3452 substrate, 7017 Transposon Transition probability model In vivo formation of gene fusions encoding hybrid 3-galactosidase Occurrence of cell division is not exponentially distributed: Differences in proteins in one step with a transposable Mu-lac transducing phage, 535 the generation times of sister cells can be derived from the theory of Long terminal repeat nucleotide sequence and specific insertion of the survival of populations, 2379 gypsy transposon, 4462 Transition-state analog "Hopeful monsters," transposons, and Metazoan radiation, 5482 Tumor cell proteinase visualization and quantification using a fluorescent Mercuric ion-resistance operons of plasmid R100 and transposon TnSOl: transition-state analog probe, 1135 The beginning of the operon including the regulatory region and the Charge state of His-57-Asp-102 couple in a transition state analogue- first two structural genes, 5975 trypsin complex: A molecular orbital study, 6266 Transposon y8 Transition temperature recA-independent recombination of y8 termini and at IS3 producing Alteration of lipid-phase behavior in multiple sclerosis myelin revealed by inverted repetition in F' plasmids, 4869 wide-angle x-ray diffraction, 1871 Transposon Tcl Translation Extrachromosomal copies of transposon Tcl in the nematode Mechanism of translational control by partial phosphorylation of the a Caenorhabditis elegans, 4018 subunit of eukaryotic initiation factor 2, 352 Transposon Tn5 Mutational analysis of a regulatory region in bacteriophage X that has Unusual alleles of recB and recC stimulate excision of inverted repeat overlapping signals for the initiation of transcription and transposons TnlO and Tn5, 824 translation, 555 Transposon TnS lac Two initiation sites detected in the small si species of reovirus mRNA by Construction of TnS lac, a transposon that fuses 1acZ expression to dipeptide synthesis in vitro, 1084 exogenous promoters, and its introduction into Myxococcus A unique mechanism regulating gene expression: Translational inhibition xanthus, 5816 by a complementary RNA transcript (micRNA), 1966 Transposon Tn1O Formation of termination-resistant transcription complex at phage X nut Unusual alleles of recB and recC stimulate excision of inverted repeat locus: Effects of altered translation and a ribosomal mutation, 3612 transposons TnlO and TnS, 824 Adenovirus tripartite leader sequence enhances translation of mRNAs Generation of a Tn5 promoter probe and its use in the study of gene late after infection, 3655 expression in Caulobacter crescentus, 1035 DNA sequence of the carA gene and the control region of carAB: Essential sites at transposon TnlO termini, 3452 Tandem promoters, respectively controlled by arginine and the Molecular analysis of the recF gene of Escherichia coli, 4622 pyrimidines, regulate the synthesis of carbamoyl-phosphate synthetase recA-independent recombination of -y termini and at IS3 producing in Escherichia coli K-12, 4134 inverted repetition in F' plasmids, 4869 Multiple regulatory signals in the control region of the Escherichia coli Transversion carAB operon, 4139 Mutational specificity of depurination, 1494 A unique mechanism regulating gene expression: Translational inhibition by a complementary RNA transcript (micRNA) (Correction), 4240 Trematode 5' untranslated sequences are required for the translational control of a Differentiation of schistosomes by species, strain, and sex by using yeast regulatory gene, 5096 cloned DNA markers, 889 Translational regulation of the L11 ribosomal protein operon of Triacylglycerol Escherichia coli: Analysis of the mRNA target site using is produced, regulated, and functional in rat oligonucleotide-directed mutagenesis, 5389 brain, 7604 Role of mRNA translational efficiency in bovine growth hormone Triazine expression in Escherichia coli, 5403 Triazine herbicide resistance in the photosynthetic bacterium Evidence for translational regulation of the activator of general amino Rhodopseudomonas sphaeroides, 6310 acid control in yeast, 6442 Trifluoperazine Escherichia coli translational initiation factor IF3: A unique case of Trifluoperazine inhibits insulin action on glucose metabolism in fat cells translational regulation, 7061 -without affecting inhibition of lipolysis, 327 Anti-mRNA: Specific inhibition of translation of single mRNA Triglyceride molecules, 7525 Metabolism of apolipoproteins B-48 and B-100 of triglyceride-rich Essential site for growth rate-dependent regulation within the Escherichia lipoproteins in normal and lipoprotein lipase-deficient humans, 1839 coli gnd structural gene, 7669 SD,14,15L-Trihydroxy-6,8,10,12-icosatetraenoic acid Affecting gene expression by altering the length and sequence of the 5' Lipoxins: Novel series of biologically active compounds formed from leader, 7698 arachidonic acid in human leukocytes, 5335 Translational mobility Tris(4,7-diphenylphenanthroline)ruthenium(ll) The translational mobility of substances within the cytoplasmic Chiral probes for the handedness of DNA helices: Enantiomers of matrix, 6747 tris(4,7-diphenylphenanthroline)ruthenium(II), 1961 Translocation Triticum NH2-terminal hydrophobic region of influenza virus neuraminidase Nucleic acid (cDNA) and amino acid sequences of a-type gliadins from provides the signal function in translocation, 2327 wheat (Triticum aestivum), 4712 Molecular model of ribosome frameshifting, 5797 Tritium transmutation In vitro translocation of bacterial proteins across the plasma membrane of Ionizing radiation and tritium transmutation both cause formation of 5- Escherichia coli, 7421 hydroxymethyl-2'-deoxyuridine in cellular DNA, 318 Transplantation tRNA Prevention of rejection of murine islet allografts by pretreatment with Distribution of two selenonucleosides among the selenium-containing anti-dendritic cell antibody, 3864 tRNAs from Methanococcus vannielii, 57 Transport Occurrence of selenium-containing tRNAs in mouse leukemia cells, 3010 See also Active transport Cross-linking of tRNA at two different sites of the elongation factor Purified reconstituted lac carrier protein from Escherichia coli is fully Tu, 3969 functional, 1629 Ribonuclease T: New exoribonuclease possibly involved in end-turnover Evidence for rotational contribution to protein-facilitated proton of tRNA, 4290 transport, 1710 Transfer RNA mischarging mediated by a mutant Escherichia coli Intramolecular dislocation of the COOH terminus of the lac carrier glutaminyl-tRNA synthetase, 5076 protein in reconstituted proteoliposomes, 4672 Molecular model of ribosome frameshifting, 5797 Identity of hepatic membrane transport systems for bile salts, phalloidin, Suppressor sufJ: A novel type of tRNA mutant that induces translational and antamanide by photoaffinity labeling, 5232 frameshifting, 6105 Na' movement in a single turnover of the Na pump, 5310 tRNA gene Transport, retrograde tau, a repeated DNA sequence in yeast, 2965 Developing dorsal root ganglion neurons require trophic support from tRNA mischarging their central processes: Evidence for a role of retrogradely transported Transfer RNA mischarging mediated by a mutant Escherichia coli nerve growth factor from the central nervous system to the glutaminyl-tRNA synthetase, 5076 periphery, 6245 tRNAAr Transposable element Chloroplast tRNAGly gene contains a long intron in the D stem: Rearranged sequences of a human Kpn I element, 1012 Nucleotide sequences of tobacco chloroplast genes for tRNAGly (UCC) tau, a repeated DNA sequence in yeast, 2965 and tRNAArg (UCU), 405 of the locus in maize a and Cloning bronze by simple generalizable tRNAGIy procedure using the transposable controlling element Activator a intron in the D stem: (Ac), 3825 Chloroplast tRNAGlY gene contains long Distribution of DNA insertion element IS5 in natural isolates of Nucleotide sequences of tobacco chloroplast genes for tRNAGIy (UCC) Escherichia coli, 4500 and tRNAArg (UCU), 405 Topological repression of gene activity by a transposable element, 6115 tRNAPMet Chromosomal mapping of a middle-repetitive DNA sequence in a cluster tRNAf2et gene in the leader region of the nusA operon in Escherichia of five species of Hawaiian Drosophila, 7146 coli, 409 Interspecific DNA transformation in Drosophila, 7515 Biological Sciences Subject Index Proc. Natl. Acad. Sci. USA 81 (1984) 8139 tRNA^b Malignant growth in the normal host after variant selection in vitro with RNA structure analysis using methidiumpropyl-EDTA-Fe(II): A base- cytolytic T-cell lines, 2186 pair-specific RNA structure probe, 6978 Induction of immunity to a human tumor marker by in vivo tRNA4TG administration of anti-idiotypic antibodies in mice, 2864 The sup-7(st5) X gene of Caenorhabditis elegans encodes a Induction of the metastatic phenotype in a mouse tumor model by amber suppressor, 6784 tRNATUXG 5-azacytidine, and characterization of an antigen associated with Trophic factor metastatic activity, 3389 Developing dorsal root ganglion neurons require trophic support from Invasive behavior of mouse sarcoma cells is inhibited by blocking a their central processes: Evidence for a role of retrogradely transported 37,000-dalton plasma membrane glycoprotein with Fab fragments, 3747 nerve growth factor from the central nervous system to the Nature and origin of the RNA associated with simian virus 40 large tumor periphery, 6245 antigen, 5425 The survival of brain transplants is enhanced by extracts from injured Synthesis in Escherichia coli of human adenovirus type 12 transforming brain, 6250 proteins encoded by early region 1A 13S mRNA and 12S mRNA, 6300 The simian virus 40 minimal origin and the 72-base-pair repeat are Trophic link required simultaneously for efficient induction of late gene expression Trophic links of community food webs, 4105 with large tumor antigen, 6335 Trophoblast Specific in vitro adenylylation of the simian virus 40 large tumor Human placental syncytiotrophoblastic Mr 75,000 polypeptide defined by antigen, 6574 antibodies to a synthetic peptide based on a cloned human endogenous Regulation of polyomavirus transcription by large tumor antigen, 6919 retroviral DNA sequence, 6197 Simian virus 40 DNA replication in vitro, 6973 Trophoblastic disease Simian virus 40 T antigen is required for viral excision from Segregation patterns of polymorphic restriction sites of the gene encoding chromosomes, 7534 the a subunit of human chorionic gonadotropin in trophoblastic Tumor cell disease, 2504 Tumor cell proteinase visualization and quantification using a fluorescent Tropics transition-state analog probe, 1135 Guatemalan forest synthesis after Pleistocene aridity, 4856 Differential adhesion of tumor cells to capillary endothelial cells in Tropomyosin vitro, 5739 Denervated skeletal muscle displays discoordinate regulation for the Interactions between human tumor cells and fibroblasts stimulate synthesis of several myofibrillar proteins, 1122 hyaluronate synthesis, 6767 Troponin Tumor formation Denervated skeletal muscle displays discoordinate regulation for the Early origin and pervasiveness of cellular heterogeneity in some synthesis of several myofibrillar proteins, 1122 malignant transformations, 5121 Trypanosoma Tumor growth Variant antigen genes of Trypanosoma brucei: Genomic alteration of a Inhibition of growth of pancreatic carcinomas in animal models by spliced leader orphon and retention of expression-linked copies during analogs of hypothalamic hormones, 248 differentiation, 684 Tumor imng Trypanosome variant-specific glycoproteins: A polygene protein family Second antibody clearance of radiolabeled antibody in cancer with multiple folding patterns?, 998 radioimmunodetection, 2843 Variant antigen genes of Trypanosoma brucei: Genomic alteration of a spliced leader orphon and retention of expression-linked copies during Necrosin: Purification and properties of a cytotoxin derived from a differentiation (Correction), 2944 murine macrophage-like cell line, 7932 Minichromosomal repetitive DNA in Trypanosoma cruzi: Its use in a Tumor promoter high-sensitivity parasite detection assay, 3356 Plasma membrane reorganization induced by tumor promoters in an Characterization of the genes specifying two metacyclic variable antigen epithelial cell line, 449 types in Trypanosoma brucei rhodesiense, 6642 Active oxygen acts as a promoter of transformation in mouse embryo The intracellular pathway and assembly of newly formed variable surface C3H/10T½2/C18 fibroblasts, 2085 glycoprotein of Trypanosoma brucei, 7703 Tumor promoters block tyrosine-specific phosphorylation of the Trypnsome epidermal growth factor receptor, 3034 Differential expression of mRNAs for a- and /-tubulin during Tumor promoters induce a specific morphological signature in the nuclear differentiation of the parasitic protozoan Leishmania mexicana, 5782 matrix-intermediate filament scaffold of Madin-Darby canine kidney Trypsin (MDCK) cell colonies, 4409 Proteolytic activation of a bioactive cardiac peptide by in vitro trypsin Suppression of the first stage of phorbol 12-tetradecanoate 13-acetate- cleavage, 1230 effected tumor promotion in mouse skin by nontoxic inhibition of DNA Charge state of His-57-Asp-102 couple in a transition state analogue- synthesis, 5858 trypsin complex: A molecular orbital study, 6266 Tumor promotion Tryrptophan Competitive inhibition by diacylglycerol of specific phorbol ester Interferon y blocks the growth of Toxoplasma gondii in human fibroblasts binding, 607 by inducing the host cells to degrade tryptophan, 908 Tumor regression Structure of human hemopexin: O-Glycosyl and N-glycosyl sites and Appearance of cytotoxic antibody to viral gp7O on feline lymphoma cells unusual clustering of tryptophan residues, 2021 (FL-74) in cats during ex vivo immunoadsorption therapy: Quantitation, Picosecond fluorescence decay of tryptophans in myoglobin, 4399 characterization, and association with remission of disease and Tryptophan operon disappearance of viremia, 3516 Characterization of the Bacillus subtilis tryptophan promoter region, 6315 Tumor rejection Tsetse fy Tumors undergoing rejection induced by monoclonal antibodies of the Characterization of the genes specifying two metacyclic variable antigen IgG2a isotype contain increased numbers of macrophages activated for types in Trypanosoma brucei rhodesiense, 6642 a distinctive form of antibody-dependent cytolysis, 3506 Tubulin Tumor-seeking agent Interference of GTP hydrolysis in the mechanism of microtubule 99mTc-labeled nucleotides as tumor-seeking radiodiagnostic agents, 918 assembly: An experimental study, 771 Tumor transplantation Tubulins from different higher plant species are immunologically Transplantation of human or rodent tumors into cyclosporine-treated nonidentical and bind colchicine differentially, 1440 mice: A feasible model for studies of tumor biology and Axonal transport of a subclass of r proteins: Evidence for the regional 7927 differentiation of microtubules in neurons, 1570 chemotherapy, Heterogeneity of vertebrate brain tubulins, 4041 Tumor virus Relationships between the structures of taxol and baccatine III Possible DNA-RNA tumor virus interaction in human lymphomas: derivatives and their in vitro action on the disassembly of mammalian Expression of retroviral proteins in Ramos lymphoma lines is enhanced brain and Physarum amoebal microtubules, 4090 after conversion with Epstein-Barr virus, 33 Differential expression of mRNAs for a- and P-tubulin during Possible DNA-RNA tumor virus interaction in human lymphomas: differentiation of the parasitic protozoan Leishmania mexicana, 5782 Expression of retroviral proteins in Ramos lymphoma lines is enhanced Involvement of the carboxyl-terminal domain of tubulin in the regulation after conversion with Epstein-Barr virus (Correction), 3918 of its assembly, 5989 Tumorigenesis Photomorphogenesis in Physarum: Induction of tubulins and sporulation- Transforming protein of avian sarcoma virus UR2 is associated with specific proteins and of their mRNAs, 7117 phosphatidylinositol kinase activity: Possible role in Tumor tumorigenesis, 2728 Induction of the metastatic phenotype in a mouse tumor model by The neurula stage mouse embryo in control of neuroblastoma, 7608 5-azacytidine, and characterization of an antigen associated with Tumorigenscity metastatic activity, 3389 Tumorigenicity of cell lines with altered lipid composition, 7622 Reduction in the incidence of radiation-induced tumors in rats after Tunicamycin restriction of food intake, 7596 Tunicamycin blocks neuritogenesis and glucosamine labeling of Tumor antigen gangliosides in developing cerebral neuron cultures, 5638 Cell surface antigens of human bladder cancer defined by mouse Turkey monoclonal antibodies, 224 Extensive homology exists between Marek disease herpesvirus and its Transformation by polyoma virus is drastically reduced by substitution of vaccine virus, herpesvirus of turkeys, 3365 phenylalanine for tyrosine at residue 315 of middle-size tumor Turtle antigen, 679 y-Aminobutyric acid acts at axon terminals of turtle photoreceptors: DNA binding activity of polyoma virus large tumor antigen, 1941 Difference in sensitivity among cell types, 7961 Stimulation of simian virus 40 late gene expression by simian virus 40 Twin tumor antigen, 2040 Ability to smell androstenone is genetically determined, 4899 8140 Biological Sciences Subject Index Proc. Natl. Acad. Sci. USA 81 (1984)

Twisted state Ultraplankton Twisted states of Bacillus subtilis macrofibers reflect structural states of Body size and food size in freshwater zooplankton, 6427 the cell wall, 3562 Ultrathin frozen section Two-bridge link An improved procedure for immunoelectron microscopy: Ultrathin plastic A simple topological method for describing stereoisomers of DNA embedding of immunolabeled ultrathin frozen sections, 5744 catenanes and knots, 3322 radiation Ty Exposure of nondividing populations of primary human fibroblasts to UV Ty-mediated gene expression of the L YS2 and HIS4 genes of (254 nm) radiation induces a transient enhancement in capacity to Saccharomyces cerevisiae is controlled by the same SPT genes, 2431 repair potentially lethal cellular damage, 781 Type C virus Induction of phenylalanine ammonia-lyase and 4-coumarate:CoA ligase Molecular cloning of a unique human T-cell leukemia virus (HTLV- mRNAs in cultured plant cells by UV light or fungal elicitor, 1102 IlMo), 993 Effect of ultraviolet radiation on production of epidermal cell thymocyte- Detection and immunochemical characterization of a primate type C activating factor/interleukin 1 in vivo and in vitro, 1198 retrovirus-related p30 protein in normal human placentas, 6501 groEL and dnaK genes of Escherichia coli are induced by UV irradiation Tyrosine and nalidixic acid in an htpR+-dependent fashion, 1499 Membranes from T and B lymphocytes have different patterns of tyrosine Removal of UV light-induced pyrimidine-pyrimidone(6-4) products from phosphorylation, 2347 Escherichia coli DNA requires the uvrA, uvrB, and urvC gene On the protein (tyrosine)-chromophore (protonated Schiff base) coupling products, 3821 in bacteriorhodopsin, 7083 Detecting protein-DNA interactions in vivo: Distribution of RNA Tyrosine aminotransferase polymerase on specific bacterial genes, 4275 Isolation and characterization of the rat tyrosine aminotransferase Induction of replicative DNA synthesis in quiescent human fibroblasts by gene, 1346 DNA damaging agents, 4828 Transcriptional activation of the rat liver tyrosine aminotransferase gene Involvement of the activated form of RecA protein in SOS mutagenesis by cAMP, 6637 and stable DNA replication in Escherichia coli, 7539 Tyrosine hydroxylase Upstream activation site Adenosine-dependent activation of tyrosine hydroxylase is defective in Upstream activation sites of the CYCI gene of Saccharomyces cerevisiae adenosine kinase-deficient PC12 cells, 4974 are active when inverted but not when placed downstream of the Electrical stimulation increases phosphorylation of tyrosine hydroxylase "TATA box", 7860 in superior cervical ganglion of rat, 7243 Uracil DNA glycosylase Calcium/phospholipid-dependent protein kinase (protein kinase C) Altered temporal expression of DNA repair in hypermutable Bloom's phosphorylates and activates tyrosine hydroxylase, 7713 syndrome cells, 757 Tyrosine kinase Hydroxymethyluracil DNA glycosylase in mammalian cells, 4003 Transforming protein of avian sarcoma virus UR2 is associated with Urea cycle phosphatidylinositol kinase activity: Possible role in Interallelic complementation in an inborn error of metabolism: Genetic tumorigenesis, 2728 heterogeneity in argininosuccinate lyase deficiency, 4480 Transforming potential of a human protooncogene (c-fpslfes) locus, 3039 Uridine Antibodies to two defined regions of the transforming protein pp60&1c Differential sleep-promoting effects of five sleep substances nocturnally interact specifically with the epidermal growth factor receptor kinase infused in unrestrained rats, 6240 system, 5911 Urine Identification of the tyrosine protein kinase from LSTRA cells by use of Thymine glycol and thymidine glycol in human and rat urine: A possible site-specific antibodies, 6676 assay for oxidative DNA damage, 5633 Phosphorylation of the nicotinic acetylcholine receptor by an endogenous Urokinase tyrosine-specific protein kinase, 6968 Monoclonal antibodies to human urokinase identify the single-chain pro- Covalently bound myristate in a lymphoma tyrosine protein kinase, 7679 urokinase precursor, 110 Tyrosine phosphorylation Identification and primary sequence of an unspliced human urokinase Transformation by polyoma virus is drastically reduced by substitution of poly(A)+ RNA, 4727 phenylalanine for tyrosine at residue 315 of middle-size tumor Uroporphyrinogen decarboxylase antigen, 679 Isolation and identification of a cDNA clone coding for rat The membrane glycoprotein encoded by the retroviral oncogene v-erb-B uroporphyrinogen decarboxylase, 3346 is structurally related to tyrosine-specific protein kinases, 704 Uteroferrin Phorbol esters potentiate tyrosine phosphorylation of epidermal growth Uteroferrin has N-asparagine-linked high-mannose-type oligosaccharides factor receptors in A431 membranes by a calcium-independent that contain mannose 6-phosphate, 2985 mechanism, 2298 Tumor-promoting phorbol ester stimulates tyrosine phosphorylation in U- v-Ha-ras p21 937 monocytes, 2762 Autophosphorylation of v-Ha-ras p21 is modulated by amino acid residue Tumor promoters block tyrosine-specific phosphorylation of the 12, 2674 epidermal growth factor receptor, 3034 Vaccination Insulin receptor is an insulin-dependent tyrosine protein kinase: Protective immunization of the squirrel monkey against asexual blood Copurification of insulin-binding activity and protein kinase activity to stages of Plasmodium falciparum by use of parasite protein homogeneity from human placenta, 3327 fractions, 229 Phosphorylation at a tyrosine residue of lipomodulin in mitogen- Schistosoma mansoni egg granuloma size reduction in challenged stimulated murine thymocytes, 4717 baboons after vaccination with irradiated cryopreserved Blockade of autocrine stimulation in simian sarcoma virus-transformed schistosomula, 3552 cells reverses down-regulation of platelet-derived growth factor Vaccine receptors, 7466 Construction of live vaccines using genetically engineered poxviruses: Tyrosine-O-sulfate Biological activity of vaccinia virus recombinants expressing the Decrease of tyrosine-O-sulfate-containing proteins found in rat fibroblasts hepatitis B virus surface antigen and the herpes simplex virus infected with Rous sarcoma virus or Fujinami sarcoma virus, 3695 glycoprotein D, 193 Comparison of the complete nucleotide sequences of the genomes of the U1 RNA neurovirulent poliovirus P3/Leon/37 and its attenuated Sabin vaccine U1 RNA-protein complex preferentially binds to both 5' and 3' splice derivative P3/Leon 12alb, 1539 junction sequences in RNA or single-stranded DNA, 6281 Epitope-specific protective immunogenicity of chemically synthesized U1 RNA gene 13-, 18-, and 23-residue peptide fragments of streptococcal M Human U1 RNA genes contain an unusually sensitive nuclease S1 protein, 2203 cleavage site within the conserved 3' flanking region, 7288 Sendai virus-specific T-cell clones: Induction of cytolytic T cells by an U2 region anti-idiotypic antibody directed against a helper T-cell clone, 2850 U2 region of Epstein-Barr virus DNA may encode Epstein-Barr nuclear Extensive homology exists between Marek disease herpesvirus and its antigen 2, 7632 vaccine virus, herpesvirus of turkeys, 3365 U2 RNA Identification and expression in Escherichia coli of merozoite stage- Clustered genes for human U2 RNA, 3811 specific genes of the human malarial parasite Plasmodium Intron splicing: A conserved internal signal in introns of animal pre- falciparum, 3690 mRNAs, 7417 Protection from rabies by a vaccinia virus recombinant containing the Ubiquitin rabies virus glycoprotein gene, 7194 Role of the a-amino group of protein in ubiquitin-mediated protein Synthesis in animal cells of hepatitis B surface antigen particles carrying breakdown, 7021 a receptor for polymerized human serum albumin, 7708 Ubiquitin-protein conjugate Both cholera toxin-induced adenylate cyclase activation and cholera toxin ATP-dependent degradation of ubiquitin-protein conjugates, 1619 biological activity are inhibited by antibodies against related synthetic UDP-hexose peptides, 7893 Further clues concerning the vectors essential to regulation of hexose Vaccinia virus transport, as studied in fibroblast cultures from a metabolic Construction of live vaccines using genetically engineered poxviruses: mutant, 1126 Biological activity of vaccinia virus recombinants expressing the Ultrabithorax hepatitis B virus surface antigen and the herpes simplex virus Homoeosis in Drosophila: The Ultrabithorax larval syndrome, 545 glycoprotein D, 193 Homoeosis in Drosophila: The Ultrabithorax larval syndrome Protection from rabies by a vaccinia virus recombinant containing the (Correction), 2273 rabies virus glycoprotein gene, 7194 Structural relationships among genes that control development: Sequence Vaccinia virus 19-kilodalton protein homology between the Antennapedia, Ultrabithorax, and fushi tarazu Vaccinia virus 19-kilodalton protein: Relationship to several mammalian loci of Drosophila, 4115 proteins, including two growth factors, 7363 Biological Sciences Subject Index Proc. NatL. Acad. Sci. USA 81 (1984) 8141

Variable region Mechanism of toxin secretion by Vibrio cholerae investigated in strains Restricted association of V and J-C gene segments for mouse X light harboring plasmids that encode heat-labile enterotoxins of Escherichia chains, 2484 coli, 7752 Diversity at the variable-joining region boundary of X light chains has a pronounced effect on immunoglobulin ligand-binding activity, 6139 Plasmid-linked nif and "nod" genes in fast-growing rhizobia that nodulate Chimeric human antibody molecules: Mouse antigen-binding domains Glycine max, Psophocarpus tetragonolobus, and Vigna with human constant region domains, 6851 unguiculata, 3093 Polymorphisms of a human variable heavy chain gene show linkage with Vimentin constant heavy chain genes, 7840 Lysosomes are associated with microtubules and not with intermediate Restricted association of VJC gene segments for mouse X light chains filaments in cultured fibroblasts, 788 (Correction), 8019 Intermediate filaments in monkey kidney TC7 cells: Focal centers and Variable surface glycoproteln interrelationship with other cytoskeletal systems, 1117 Characterization of the genes specifying two metacyclic variable antigen Identification of glial filament protein and vimentin in the same types in Trypanosoma brucea rhodesiense, 6642 intermediate filament system in human glioma cells, 2102 The Intracellular pathway and assembly of newly formed variable surface Fc-mediated binding of IgG to vimentin-type intermediate filaments in glycoprotein of Trypanosoma brucei, 7703 vascular endothelial cells, 3103 Variant-specific glycoprotein Intermediate filament cDNAs from BHK-21 cells: Demonstration of Trypanosome variant-specific glycoproteins: A polygene protein family distinct genes for desmin and vimentin in all vertebrate classes, 5970 with multiple folding patterns?, 998 Vinblastine Variant surface glycoprotein Imbalance of total cellular nucleotide pools and mechanism of the Variant antigen genes of Trypanosoma brucei: Genomic alteration of a colchicine-induced cell activation, 2401 spliced leader orphon and retention of expression-linked copies during Viral excision differentiation, 684 Simian virus 40 T antigen is required for viral excision from Variant antigen genes of Trypanosoma brucei: Genomic alteration of a chromosomes, 7534 spliced leader orphon and retention of expression-linked copies during Virulence differentiation (Correction), 2944 Synthesis of cholera toxin is positively regulated at the transcriptional Varicella zoster virus level by toxR, 3471 Dose-related effect of acetylsalicylic acid on replication of varicella zoster Viru virus in vitro, 5223 Simultaneous in situ detection of viral RNA and antigens, 5445 Vas deferens Virus attenuation Highly selective photoaffinity labeling of s and 8 opioid receptors, 7718 Comparison of the complete nucleotide sequences of the genomes of the Vascular endothelial cell neurovirulent poliovirus P3/Leon/37 and its attenuated Sabin vaccine Fc-mediated binding of IgG to vimentin-type intermediate filaments in derivative P3/Leon 12alb, 1539 vascular endothelial cells, 3103 Virus Integration Vasodilatlon A mutant murine leukemia virus with a single missense codon in pol is Atrial natriuretic factor elicits an endothelium-independent relaxation and defective in a function affecting integration, 6461 activates particulate guanylate cyclase in vascular smooth muscle, 7661 Integration-specific retrovirus expression in embryonal carcinoma Vasopresin cells, 6627 Method for quantitating the molecular content of a subcellular organelle: Virus latency Hormone and neurophysin content of newly formed and aged Herpes simplex virus latency in isolated human neurons, 6217 neurosecretory granules, 180 Virus neutralization Corticotropin-releasing factor-immunoreactive neurons of the Murine monoclonal antibody to a single protein neutralizes the infectivity paraventricular nucleus become vasopressin positive after of human cytomegalovirus, 876 adrenalectomy, 1854 Method to map antigenic determinants recognized by monoclonal Co-expression of corticotropin-releasing factor and vasopressin antibodies: Localization of a determinant of virus neutralization of the immunoreactivity in parvocellular neurosecretory neurons of the feline leukemia virus envelope protein gp7O, 3675 adrenalectomized rat, 1883 Virus replication Structure and comparison of the oxytocin and vasopressin genes from DNA and RNA virus species are inhibited by xanthates, a class of rat, 2006 antiviral compounds with unique properties, 3263 Vasopressin gene Virus rescue Vasopressin gene is expressed at low levels in the hypothalamus of the Frequent generation of nonrescuable reorganized Moloney murine Brattleboro rat, 52% sarcoma viral genomes, 294 Vasopressin receptor Viscosity Properties of rat anterior pituitary vasopressin receptors: Relation to Diffusion of a small molecule in the cytoplasm of mammalian cells, 3414 adenylate cyclase and the effect of corticotropin-releasing factor, 2907 Vision Regional distribution of putative vasopressin receptors in rat brain and Sensitive light scattering probe of enzymatic processes in retinal rod pituitary by quantitative autoradiography, 7248 photoreceptor membranes, 743 Vasorelaxant Effects of monocular deprivation on the lateral geniculate nucleus in a Specific membrane receptors for atrial natriuretic factor in renal and primate, 2255 vascular tissues, 5946 Function of the thalamic reticular complex: The searchlight Vector hypothesis, 4586 Constitutive production of human interferons by mouse cells with bovine Isolation and nucleotide sequence of the gene encoding human papillomavirus as a vector, 5086 rhodopsin, 4851 Introduction of a selectable gene into different animal tissue by a Visna virus retrovirus recombinant vector, 7151 Slow virus visna: Reproduction in vitro of virus from extrachromosomal Venom DNA, 7212 Spider venoms inhibit L-glutamate binding to brain synaptic membrane Visual cortex receptors, 5571 Segregation of on- and off-center afferents in mink visual cortex, 1590 Ventricular fibrillation Numbers of specific types of neuron in layer IVab of cat striate Simple finite-element model accounts for wide range of cardiac cortex, 3898 dysrhythmias, 233 Visual deprivation Veratridine Labile nature of the visual recovery promoted by reverse occlusion in Reconstitution of neurotoxin-modulated ion transport by the voltage- monocularly deprived kittens, 286 regulated sodium channel isolated from the electroplax of Visual pigment Electrophorus electricus, 1239 Fluorescence quantum yield of visual pigments: Evidence for Vertebrate subpicosecond isomerization rates, 4790 vertebrates from Antigua, Lesser Antilles: Evidence for late Vitamin A Holocene human-caused extinctions in the West Indies, 4448 Differences in keratin synthesis between normal epithelial cells and Very low density lipoprotein squamous cell carcinomas are mediated by vitamin A, 4280 Increased free cholesterol in plasma low and very low density Cloning of cDNAs specifying vitamin A-responsive human keratins, 4321 lipoproteins in non-insulin-dependent diabetes mellitus: Its role in the inhibition of cholesteryl ester transfer, 2512 Vitamin B-6 Role of apolipoprotein E in the lipolytic conversion of (-very low density Enzymology of the response of the carpal tunnel syndrome to riboflavin lipoproteins to low density lipoproteins in type III and to combined riboflavin and pyridoxine, 7076 hyperlipoproteinemia, 5566 Vitamin B-12 Vesicular stomatitis virus Methyl transfer from methylcobalamin to diaquocobinamide, 2698 Chimeric influenza virus hemagglutinin containing either the NH2 Vitamin C terminus or the COOH terminus of G protein of vesicular stomatitis See Ascorbic acid virus is defective in transport to the cell surface, 395 Vitamin D Injection of mice with antibody to interferon renders peritoneal Phagocytic cells metabolize 25-hydroxyvitamin D3 in vitro, 931 macrophages permissive for vesicular stomatitis virus and Interaction of the la,25-dihydroxyvitamin D3 receptor with RNA and encephalomyocarditis virus, 602 synthetic polyribonucleotides, 2337 The presence of cysteine in the cytoplasmic domain of the vesicular Complex carbohydrate diets are not capable of maintaining normal stomatitis virus glycoprotein is required for palmitate addition, 2050 plasma calcium and phosphorus levels in vitamin D-deficient rats, 2352 Pseudotypes of human T-cell leukemia virus types 1 and 2: Neutralization Subcellular distribution of DNA-binding and non-DNA-binding 1,25- by patients' sera, 2886 dihydroxyvitamin D receptors in chicken intestine, 6711 Vibrio Activation and fusion induced by la,25-dihydroxyvitamin D3 and their Identification of genes and gene products necessary for bacterial relation in alveolar macrophages, 7112 bioluminescence, 4154 8142 Biological Sciences Subject Index Proc. NatL Acad ScL USA 81 (1984)

Vitamin K Developmental control of the heat shock response in Xenopus, 3138 Mechanism of the inhibition of the y-carboxylation of glutamic acid by N- Alteration of the retinotectal map in Xenopus by antibodies to neural cell methylthiotetrazole-containing antibiotics, 2893 adhesion molecules, 4222 Cloning and sequencing of liver cDNA coding for bovine protein C, 5653 In vivo effects of microinjected alkaline phosphatase and its low Vitellogenin Molecular weight substrates on the first meiotic cell division in Preferential binding of estrogen-receptor complex to a region containing Xenopus laevis oocytes, 5150' the estrogen-dependent hypomethylation site preceding the chicken A Ca2+-activated channel from Xenokus laevis oocyte membranes vitellogenin II gene, 429 reconstituted into planar bilayers, 5155 Injection of partially purified estrogen receptor protein from Xenopus Injection of partially purified estrogen receptor protein from Xenopus liver nuclei into oocytes activates the silent vitellogenin locus, 5777 liver nuclei into oocytes activates the silent vitellogenin locut, 5777 Viviparity Xeroderma pigmentosum Eutherian-like reproductive specializations in a viviparous reptile, 4860 Exposure of nondividing populations of primary human fibroblasts to UV von Willebrand factor (254 nm) radiation induces a transient enhancement in capacity to von Willebrand protein binds to extraczellular matrices independently of repair potentially lethal cellular damage, 781 collagen, 471 Transient complementation of xeroderma pigmentosum cells by ADP-dependent common receptor mechanism for binding of von microinjection of poly(A)+ RNA, 5676 Willebrand factor and fibrinogen to human platelets, 4935 Yeast Warbler See also Saccharomyces Neophobia in the foraging-site selection of a neotropical migrant bird: An Steps in processing of the mitochondrial cytochrome oxidase subunit I study, 3778 pre-mRNA affected by a nuclear mutation in yeast, 8 experimental Primary structure and transcription of an amplified genetic locus: The Wasp CUP) locus of yeast, 337 Selective destruction of a host blood cell type by a parasitoid wasp, 6154 Regulated expression of a human interferon gene in yeast: Control by Water phosphate concentration or temperature, 367 Water structure of a hydrophobic protein at atomic resolution: Pentagon Elaboration of telomeres in yeast: Recognition and modification of rings of water molecules in crystals of crambin, 6014 termini from Oxytricha macronuclear DNA, 1475 Water flow tau, a repeated DNA sequence in yeast, 2965 Water flow and coral colony size: Interhabitat comparisons of the Expandable var) gene of yeast mitochondrial DNA: In-frame insertions octocoral Alcyonium siderium, 5473 can explain the strain-specific protein size polymorphisms, 3148 Water solubility Copper metallothionein of yeast, structure of the gene, and regulation of The effects of water-soluble solutes on the phase transitions of expression, 3332 phospholipids, 1398 Genes required for initiation and resolution steps of mating-type switching Wax in fission yeast, 3481 Alkane biosynthesis by decarbonylation of aldehydes catalyzed by a Isolation of the yeast INOI gene: Located on an autonomously particulate preparation from Pisum sativum, 6613 replicating plasmid, the gene is fully regulated, 3816 West Indies Differential regulation of the duplicated isocytochrome c genes in Fossil vertebrates from Antigua, Lesser Antilles: Evidence for late yeast, 4475 Holocene human-caused extinctions in the West Indies, 4448 Two nuclear mutations that block mitochondrial protein import in Wheat yeast, 4819 Pronounced structural similarities between the small subunit ribosomal 5' untranslated sequences are required for the translational control of a RNA genes of wheat mitochondria and Escherichia coli, 493 yeast regulatory gene, 5096 Nucleic acid (cD)NA) and amino acid sequences of a-type gliadins from Cross-reactions of polysaccharides of fungi, molds, and yeasts in anti- wheat (Triticum aestivum), 4712 pneumococcal and other antisera, 5247 Oxygen regulation of anaerobic and aerobic genes mediated by a common White-rot fungi factor in yeast, 6129 Lignin-degrading enzyme from Phanerochaete chtysosporium: Evidence for translational regulation of the activator of general amino Purification, characterization, and catalytic properties of a unique acid control in yeast, 6442 H202-requiring oxygenase, 2280 A product of yeast RAS2 gene is a guanine nucleotide binding Wood decay protein, 6924 Lignin-degrading enzyme from Phanerochaete chrysosporium: Yeast mitochondrial genomes consisting of only A-T base pairs replicate Purification, characterization, and catalytic properties of a unique and exhibit suppressiveness, 7156 H202-requiring oxygenase, 2280 Changing patterns of gene expression during sporulation in yeast, 7323 Wood rat An immunological method for detecting gene expression in yeast Seasonal aggression independent of seasonal testosterone in wood colonies, 7426 rats, 5255 Genetic properties and chromatin structure of the yeast gal regulatory Woodchuck hepatitis virus element: An enhancer-like sequence, 7865 Transmission of the hepatitis B virus-associated 6 agent to the eastern Yellow phenotype woodchuck, 2208 Differential effects of the mottled yellow and pseudoagouti phenotypes on Predicted secondary structure similarity in the absence of primary amino immunocompetence in AvY/a mice, 2152 acid sequence homology: Hepatitis B virus open reading frames, 2902 Yolk sac Wound signal insulin in the fetal 3635 Wound signals in plants: A systemic plant wound signal alters plasma Extrapancreatic gene expression rat, membrane integrity, 3737 Z-DNA Wren 0 Chiral probes for the handedness of DNA helices: Enantiomers of Population differences in complexity of a learned skill are cprrelated with tris(4,7-diphenylphenanthroline)ruthenium(II), 1961 the brain space involved, 6232 In Z-DNA the sequence G-C-G-C is neither methylated by Hha I methyltransferase nor cleaved by Hha I restriction endonuclease, 3268 X chromosome Statistical mechanics of the B -- Z transition of DNA: Contribution of See Chromosome X diffuse ionic interactions, 5116 X-ray Restriction endonucleases can be used to study B-Z junctions in mu-2: Mutator gene in Drosophila that potentiates the induction of supercoiled DNA, 5714 terminal deficiencies, 6090 Salt-induced Z-A-Z transition sequence in the mixed ribo-deoxyribo X-ray diffraction copolymer poly(rG-dC)-poly(rG-dC), 7284 Crystallization of myosin subfragment 1, 4378 Z scheme X region Photoreduction of ferredoxin with various electron donors: Support for Nucleotide sequence of the 3' region of an infectious human T-cell the Z scheme of photosynthetic electron transport, 2070 leukemia virus type II genome, 6657 Zellweger cerebro-hepato-renal syndrome Xanthate Lignoceric acid is oxidized in the peroxisome: Implications for the DNA and RNA virus species are inhibited by xanthates, a class of Zellweger cerebro-hepato-renal syndrome and antiviral compounds with unique properties, 3263 adrenoleukodystrophy, 4203 Xanthine oxidase Zinc 6-Deoxyacyclovir: A xanthine oxidase-activated prodrug of Modulation of cholecystokinin concentrations in the rat hippocampus by acyclovir, 3209 chelation of heavy metals, 5876 Xenopsin Structural stability of the 4-zinc human insulin hexamer, 7093 Xenopsin: The neurotensin-like octapeptide from Xenopus skin at the Zooplankton carboxyl terminus of its precursor, 380 Effect of selenium deficiency on cuticle integrity in the Cladocera Xenopus (Crustacea), 3433 Perpendicular orientation and directional migration of amphibian neural Body size and food size in freshwater zooplankton, 6427 crest cells in dc electrical fields, 160 Xenopsin: The neurotensin-like octapeptide from Xenopus skin at the carboxyl terminus of its precursor, 380