Curriculum Vitae

Name: Raymond F. Johnson

Office Phone: 615-322-4496 Neurochemistry Core Lab 465 21st Ave. S MRB III Room 6141 (8548) Office Address: Nashville Tennessee, 37232-8548 Work Email: [email protected]

Training

1970 B.S. from Belmont University, TN United States

Academic Appointments

07/1991 - 08/1995 , Vanderbilt University (Nashville, Tennessee) 08/1995 - 06/2008 Associate in, Vanderbilt University (Nashville, Tennessee) 07/2008 - 06/2021 Associate in Anesthesiology, Vanderbilt University (Nashville, Tennessee)

Other Work Experience

1996 - Present Associate, Vanderbilt University Medical Center

Other Significant Activities

Lab Manager, Obstetric Anesthesiology: Established the HPLC / Placental 07/1991 Perfusion Lab Lab Manager, CMN/KC Neurochemistry Core Laboratory: Established the Core 09/1999 in 1999, and developed all core assays and protocols.

Grants and Funding

5P30 HD015052-28 07/2005 - 06/2009 National Institute of Child Health and Human Development John F. Kennedy Center for Mental Retardation Total Cost: $6,768,825.00

1P50 MH078028-01A1 09/2007 - 06/2008 National Institute of Mental Health Genes Controlling Assembly and Function of Serotonin Systems Total Cost: $9,488,360.00

Honors / Awards

1969 Laboratory Assistantship 1970 B.S. cum laude 1972 VA Merit Award 1975 VA Merit Award

Publications

Peer Reviewed Publications

Research Papers 1. Minzter BH, Johnson RF, Paschall RL, Ramasubramanian R, Ayers GD, Downing JW. The diverse effects of vasopressors on the fetalplacental circulation of the dual perfused human placenta. Anesth Analg 2010 March;110(3):857-862.

Research Articles 1. McHorse TS, Wilkerson GR, Johnson RF, Schenker S. The effects of acute viral hepatitis in man on the disposition and elimination of meperidine. Gastroenterology 1975; 68:775-780. 2. Shull HJ Jr, Wilkinson GR, Johnson RF, Schenker S. Normal dispostion of oxazepam in acute viral hepatitis and cirrhosis. Ann Intern Med 1976; 84:420-425. 3. Dunkerly R, Johnson RF, Schenker S, Wilkerson GR. Gastric and biliary excretion of meperidine in man. Clin Pharmacol Ther 1976; 20:546-551. 4. Kraus JW, Desmond PV, Marshall JP, Johnson RF, Schenker S, Wilkerson GW. Effects of aging and liver on the disposition of lorazepam. Clin Pharmacol Ther 1978; 24:411-419. 5. Hoyumpa AM Jr, Desmond PV, Roberts RK, Nichols S, Johnson RF, Schenker S. Effects of ethanol on benzodiazepine disposition in dogs. J Lab Clin Med 1980; 95:310-322. 6. Desmond PV, Patwardin RV, Johnson RF, Schenker S. Impaied elimination of caffeine in cirrhosis. Dig Dis & Sci 1980; 25:193-197. 7. Patwardin RV, Yarborough GW, Desmond PV, Johnson RF, Schenker S, Speeg KV Jr. Cimetidine spares the glucuronidation of lorazepam and oxazepam. Gastroenterology 1980; 79:912-916. 8. Patwardhan RV, Desmond PV, Johnson RF, Dunn GD, Robertson DH, Hoyumpa AM Jr, Schenker S. Effects of caffeine on plasma free fatty acids, urinary catecholamines and drug binding. Clin Pharmacol Ther 1980; 28:398-403. 9. Hoyumpa AM Jr, Padwardhan RV, Maples M, Desmond PV, Johnson RF, Schenker S. Effectt of ethanol administration on lorazepam clearance. Hepatology 1981; 1:47-53. 10. Patwardhan RV, Johnson RF, Sinclair AP, Schenker S, Speeg KV Jr. Lack of tolerance and rapid recovery of cimetidine inhibited chlordiazepoxide (Librium) elimination. Gastroenterology 1981; 81:547-552. 11. Patwardhan RV, Johnson RF, Hoyumpa AM Jr, Sheehan JJ, Desmond PV, Wilkinson GR, Branch RA, Schenker S. Normal metabolism of morphine in cirrhosis. Gastroenterology 1981; 81:1006-1011. 12. Patwardhan RV, Mitchell M, Johnson RF, Schenker S. Differential effects of oral contraceptives steroids on the metabolism of benzodiazepines. Hepatology 1983; 3:248-253. 13. Branch RA, Cothan R, Johnson RF, Porter J, Desmond PV, Schenker S. Periportal localization of lorazepam glucuronidation in the isolated perfused rat liver. J Lab Clin Med 1983; 102. 14. Mitchell MC, Hoyumpa AH, Schenker S, Johnson RF, Nichols S, Patwardhan RV. Inhibition of caffeine elimination by short-term ethanol administration. J Lab Clin Med 1983; 101:826-834. 15. Meredith C, Christian D, Johnson RF, Madhavan SV, Schenker S. Diphenylhyramine disposition in chronic liver disease. Clin Pharm & Therapeu 1984; 35:474-479. 16. Meredith C, Christian D, Johnson RF, Troxell R, Davis G, Schenker S. Effects of influenza virus vaccine on hepatic drug metabolism. Clin Pharm & Therapeu 1985; 37:396. 17. Secor JW, Speeg KV Jr, Meredith CG, Johnson RF, Snowdy P, Schenker S. Lack of effect of nizatidine on hepatic drug metabolism in man. Pharmacol 1985; 20:710-713. 18. Jacqz E, Ward S, Johnson RF, Schenker S, Gerkens J, Branch R. Extrahepatic glucuronidation of morphine in the dog. Drug Metab Disp 1986; 14:627-630. 19. Roberts RK, Heath CA, Johnson RF, Speeg KV, Schenker S. Effects of H2-receptor antagonists on steady state extraction of indocyanine green and lidocaine by the perfused rat liver. J Lab Clin Med 1986; 107. 20. Schenker S, Dicke J, Johnson RF, Mor L, Henderson GI. Human placental transfer of cimetidine. J Clin Invest 1987; 80:1428. 21. Dicke JM, Johnson RF, Henderson GI, Kuehl TJ, Schenker S. A comparative valuation of the transport of H2-receptor antagonists by the human and baboon placenta. Am J Med Sci 1988; 295:198-206. 22. Hoyumpa A, Brown M, Johnson RF, Troxell R, Snowdy P, Schenker S. Effects of age and liver disease on the glucuronidation of ciramadol in humans. J Clin Pharmacol 1989; 29:217-224. 23. Schenker S, Dicke JM, Johnson RF, Hays SE, Henderson GI. Effects of ethanol on human placental transport of model amino acids and glucose. Clin Exp Res 1989; 123:112-119. 24. Schenker S, Johnson RF, Hays SE, Ganeshappa R, Henderson GI. Effects of nicotine and nicotine/ethanol on human placental amino acid transfer. Alcohol 1989; 6:289-296. 25. Leighton JA, Bay MK, Maldonado AL, Johnson RF, Schenker S, Speeg KV Jr. The effect of liver dysfunction on colchicine pharmacokinetics in the rat. Hepatology 1990; 200. 26. Schenker S, Johnson RF, King TS, Schenken RS, Henderson GI. Azidothymidine (zidovudine) transport by the human placenta. Am J Med Sci 1990; 299:16-20. 27. Schenker S, Johnson RF, Hoyumpa AM Jr, Henderson GI. Thiamine transfer by the human placenta: Normal transport and effects of ethanol. J Lab Clin Med 1990; 116:106-115. 28. Elliott BD, Langer O, Schenker S, Johnson RF. Insignificant transfer of glyburide occurs across the human placenta. Amer J Obstet Gynecol 1991; 165:807-812. 29. Henderson GI, Hu Z-Q, Johnson RF, Perez T, Yang Y, Schenker S. Acyclovir transport by the human placenta. J Lab Clin Med 1992; 120:885-892. 30. Schenker S, Coburn SP, Mahuren JD, Johnson RF, Henderson GI. Vitamin B6 (Pyridoxal) transport by the human placenta: normal characteristics and effects of short-term alcohol. Amer J Physiol 1992; 262:R966-R974. 31. Beer WH, Johnson RF, Guentzel MN, Lozano J, Henderson GI, Schenker S. Human placental transport of zinc: normal characteristics and role of ethanol. Alcoholism: Clin Exp Res 1992; 16:98-104. 32. Schenker S, Hu Z-Q, Johnson RF, Yang Y, Henderson GI, King T, Schenken RS. Human placental biotin transport: normal characteristics and effects of ethanol. Alcoholism: Clin Exp Res 1993; 17:566-575. 33. Schenker S, Johnson RF, Yang Y, Hendderson GI, King T, Sckenken RS. Transport of cocaine and its metabolites by the human placenta. Clin Pharmacol Ther 1993; 53:329-339. 34. Elliott B, Schenker S, Langer O, Johnson R, Prihoda. Oral hypoglycemia agents: profound variation exists in their rate of human placental transfer. Obstet Gynecol 1994; 171:653-660. 35. Johnson, RF, Herman, N, Arney, TL, Gonzalez, H, Johnson, HV, Downing, JW. Bupivacaine transfer across the human term placenta. A study using the dual perfused human placental model. Anesthesiology 1995; 82(2) PMID: 7856904. 36. Yang YQ, Lee MP, Schenken RS, Henderson GI, Schenker S, Johnson RF. Effects of binding on human transplacental transfer of cocaine. Amer J Obstet Gynecol 1995; 172:720-722. 37. Franks JJ, Janicki PK, Horn J-L, Singh G, Sastry BV Rama, Surber MJ, Jansen VE, Franks WT, Catlin RW, Johnson RF. Inhibition of synaptic plasma membrane Ca2+ -ATPase by inhalational anesthetics and its association with mechanisms of general anethesia. PAM 1995; 3:262-267. 38. Johnson, RF, Herman, NL, Johnson, HV, Arney, TL, Paschall, RL, Downing, JW. Effects of fetal pH on local anesthetic transfer across the human placenta. Anesthesiology 1996; 85(3) PMID: 8853092. 39. Janicki PK, Johnson RF, Kambam JR. Rapid determination of chloroprocaine and its major metabolite 2-chloroaminobenzoic acid in plasma by high-performance liquid chromatography. Journal of Chromatography 1996; 675:336-341. 40. Sastry, BV, Hemontolor, ME, Chance, MB, Johnson, RF. Dual messenger function for prostaglandin E2 (PGE2) in human placenta. Cell Mol Biol (Noisy-le-grand) 1997; 43(3) PMID: 9193797. 41. Downing, JW, Johnson, HV, Gonzalez, HF, Arney, TL, Herman, NL, Johnson, RF. The pharmacokinetics of epidural lidocaine and bupivacaine during cesarean section. Anesth Analg 1997; 84(3) PMID: 9052295. 42. Johnson, RF, Cahana, A, Olenick, M, Herman, N, Paschall, RL, Minzter, B, Ramasubramanian, R, Gonzalez, H, Downing, JW. A comparison of the placental transfer of ropivacaine versus bupivacaine. Anesth Analg 1999; 89(3) PMID: 10475309. 43. Johnson, RF, Herman, N, Arney, TL, Olenick, M, Paschall, RL, Johnson, HV, Downing, JW. Transfer of lidocaine across the dual perfused human placental cotyledon. Int J Obstet Anesth 1999; 8(1) PMID: 15321171. 44. Herman NL, Li AT, Van Decar TK, Johnson RF, Bjoraker RW, Downing JW, Jones D. Transfer of methohexital across the perfused human placenta. J Clin Anesth 2000; 12:25-30. 45. Janicki, PK, Higgins, MS, Janssen, J, Johnson, RF, Beattie, C. Comparison of two different temperature maintenance strategies during open abdominal surgery: upper body forced-air warming versus whole body water garment. Anesthesiology 2001; 95(4) PMID: 11605926. 46. Janicki PK, Higgins MS, Janssen J, Johnson RF. Comparison of two different temperature maintenance strategies during open abdonominal surgery. Anesthesiology 2001; 95:868-874. 47. Coates KM, Mather LE, Johnson R, Flood P. Thiopental is a competitive inhibitor at the human alpha 7 nicotinic acetylcholine receptor. Anesth Analg 2001; 94:930-933. 48. Minzter, BH, Johnson, RF, Grimm, BJ. The practice of thoracic epidural analgesia: a survey of academic medical centers in the United States. Anesth Analg 2002; 95(2) PMID: 12145074. 49. Downing, JW, Ramasubramanian, R, Johnson, RF, Minzter, BH, Paschall, RL, Sundell, HW, Engelhardt, B, Lewis, R. Hypothesis: selective phosphodiesterase-5 inhibition improves outcome in preeclampsia. Med Hypotheses 2004; 63(6) PMID: 15504576. 50. Ramasubramanian R, Johnson RF, Downong JW, Minzter BH, Paschall RL. Hypoxemic fetoplacental vasoconstriction: A graded response to reduced oxygen conditions in the human placenta. Anesth Analg 2006; 103:439-442.

Abstracts 1. Sherwood E, DiLuzio N. Glucan-induced production of specific antitumor cytotoxin by macrophages. Int J Immunopharmacol 1985; 7:303. 2. Johnson RF, Johnson HV, Wood M, Herman N and Downing JW. Lidocaine pharmacokinetics after epidural anesthesia for cesarean section. Anesthesiology 1993; 77:A981. 3. Sastry BVR, Chance MB, Goddijn-Wessel TAW, Johnson RF. The human placenal transfer of nicotine. Pharmacologist 1993; 34:148. 4. Johnson RF, Johnson V, Herman N, Downing JW. Bupivacaine transfer across the human term placenta. Anesth Analg 1993 March;76:S168. 5. Johnson RF, Johnson V, Gonzales, Arney T, Herman N, Downing JW. Bupivacaine pharmacokinetics after epidural anesthesia for cesarean section. Anesthesiology 1993 September;79:A1015. 6. Downing JW, Johnson V, Arney T, Gonzales H, Herman N, Johnson RF. Bupivacaine / Lidocaine pharmacokinetics after concurrent epidural anesthesia for cesarean section. Regional Anesthesia 1994; 19:S2:96. 7. Johnson RF, Johnson V, Gonzales H, Arney T, Herman N, Downing JW. The effect of protein binding on the placental transfer of bupivacaine. Anes Analg 1994; 78:S178. 8. Johnson RF, Arney TL, Johnson HV, Herman N, Downing JW. The effect of pH on the human placental transfer of bupivacaine. Anesthesiology 1994; 81:A1180. 9. Johnson RF, Johnson HV, Arney TL, Paschall RL, Herman N, Downing JW. The placental transfer of sufentanil: effects of fetal pH. Anesthesiology 1995; 83:A936. 10. Johnson RF, Janicki PK, Sastry BVR, Kambam JR. Placental uptake and transfer of benzoylecgonine and ecgonine. Anesthesiology 1995; 83:A931. 11. Johnson RF, Arney TL, Johnson HV, Herman N, Downing JW. The effect of pH on the human placental transfer of lidocaine. Anesth Analg 1995; 80. 12. Johnson RF, Paschall R, Johnson HV, Arney T, Downing JW. The placental transfer of 2- choloroprocaine across the human term placenta: the effect of fetal pH. Regional Anesthesia 1995; 20:2S:153. 13. Downing JW, Johnson HV, Arney TL, Paschall RL, Olenick M, Johnson RF. Differential effects of three vasoactive agents on fetal perfusion pressures during in vitro placental perfusion. Anesth Analg 1996; 82:S96. 14. Horn J-L, Johnson RF, Janicki PK, Franks JJ. Halothane transfer across the human term placenta. Anesth Analg 1996; 82:S188. 15. Johnson RF, Downing JW, Sastry BVR. The effects of ephedrine, phenylephrine and methoxamine on fetal intravillous vascular pressure during in vitro placental perfusion. Placenta 1996; 17:A27. 16. Sastry BVR, Graham MH, Johnson RF. Influences of bupivacaine on the prostaglandin E2 - induced umbilical pressor response in perfused human placental cotyledon. Placenta 1996; 17. 17. Badr AE, Higgins S, Clarkson KP, Dalton HU, Johnson RF. Comparison of intravenous and trantracheal administration of lidocaine for tracheal anesthesia in awake fiberoptic intubation. Anesthesiology 1996; 85:A226. 18. Arney TL, Downing JW, Johnson HV, Paschall RL, Herman N, Olenick M, Dimowo JO, Johnson RF. The effect of fetal pH and maternal protein binding on local anesthetic transfer across the human term placenta. Anesthesiology 1996; 85:A886. 19. Janicki PK, Durrani M, Brock J, Johnson R, Kambam JR. Chloroprocaine pharmacokinetics study using high performance liquid chromatographic method in humans. Anesthesiology 1996; 85:A313. 20. Minzter BH, Johnson RF, Arney TL, Olenick M, Paschall RL, Ramasubramanian R, Downing JW. A comparison of the placental transfer of ropivacaine versus bupivacaine. Anesthesiology 1997; 87:A878. 21. Minzter BH, Johnson RF, Arney TL, Olenick M, Paschall RL, Ramasubramanian R, Downing JW. The effects of halothane on the placental hypoxic vasoconstrictor response (PHVR). Anesthesiology 1997; 87:A920. 22. Durrani M, Janicki PK, Brock J, Johnson R, Kambam JR. Effects of chloroprocaine and lidocaine on the hemodynamic changes and catecholamine levels following laryngoscopy and tracheal intubation. Anesth Analg 1997; 84:S447. 23. Johnson RF, Olenick M, Minzter B, Ramasubramanian R, Paschall RL, Arney TL, Gonzales H, Downing JW. A comparison of the placental transfer of ropivacaine versus bupivacaine: effect of maternal protein binding. Anesth Analg 1998; 86:S375. 24. Johnson RF, Minzter B, Ramasubramanian R, Paschall RL, York J, Downing JW. Sodium nitroprusside (SNP) obtunds the vasopressor action of 5-hydroxytrptamine (5-HT) on the placental intravillous circulation. Anesthesiology 2000; 93:A107. 25. Downing JW, Ramasubramanian R, Minzter BH, Paschall PL, York J, Johnson RF. Response of the fetoplacental vasculature to graded hypoxia: a study using the isolated, dual perfused, single human placental cotyledon. Anesthesiology 2000; 93:A108. 26. Johnson RF, Minzter B, Ramasubramanian R, Paschall RL, York J, Downing JW. Sodium nitroprusside (SNP) obtunds the vasopressor action of 5-hydroxytrptamine (5-HT) on the placental intravillous circulation. Anesth Analg 2000; 90:S290. 27. Herman NL, Hollmann C, Idrees MT, Gaslin M, Johnson RF, Downing JW. Effect of thiopental on vascular resistance in human placental chorionic arteries under conditions of hyper-, norm-, and hypoxia. Anesth Analg 2000; 90:S288. 28. Downing JW, Ramasubramanian R, Minzter BH, Paschall PL, York J, Johnson RF. Phosphodiesterase (PDE5) receptor inhibition moderates the vasopressor effects of 5- hydroxytrptamine (5-HT) on the placental vasculature. Anesthesiology 2001; 94:A50. 29. Downing JW, Ramasubramanian R, Minzter BH, Paschall PL, York J, Johnson RF. Phosphodiesterase (PDE5) receptor inhibition obtunds hypoxic fetoplacental vasoconstriction (HFPV) in the human placenta. Anesthesiology 2001; 94:A51. 30. Moore MC, Geho WB, DiCostanzo CA, Lautz M, Farmer B, Neal DW, Johnson R, Cherrinton AD. Portal serotonin enhances net hepatic glucose uptake but blunts nonhepatic glucose uptake. Diabetologia 2003; 46:A200. Non-Peer Reviewed Publications

Review Articles 1. Downing, JW, Baysinger, CJ, Johnson, RF, Paschall RL. Review: potential druggable targets for the treatment of early onset preeclampsia. Pregnancy Hypertension: An International Journal of Women"s Cardiovascular Health 2013 April;(Apr, 2013).

Editorials 1. Downing JW, Baysinger CL, Johnson RF, Paschall RL. Reversed umbilical arterial end diastolic flow, sildenafil treatment, and early stillbirths. BJOG: An International Journal of Obstetrics and Gynaecology 2012 March;119(4):509-510.

Abstracts 1. Baysinger, CL, Johnson, RF, Downing, JW, Denton, J. Oxytocin and agrinine vasopressin do not alter vascular resistance in the fetoplacental circulation of the dual-perfused human placenta. Society for Obstetric Anesthesia and Pernatology, Monterrey, CA 2012 May. 2. Baysinger, CJ, Johnson, RF, Downing, JW, Denton, J. Hydrogensulfide in high concentrations vasodilates the fetoplacental circulations in the dual-perfused, single isolated human placental cotyledon. Society for Obstetric Anesthesia and Pernatology, San Juan, Puerto Rico. 2013 April.

Presentations

Presentations at Scientific Meetings 1. Mouton S, Horn J-L, Singh G, Janson V, Johnson R, Catlin R, Sastry BVR, Kambam JR. Society for Obstetric Anesthesia and perinatology. SOAP; Charleston, South Carolina. 1993 May; The protective effect of magnesium on cocaine toxicity. 2. Johnson RF, Johnson HV, Arney TL, Gonzalez H, Herman N, Downing JW. Society for Obstetric Anesthesia and perinatology. SOAP; Philadelphia, Pennsylvania. 1994 May; Lidocaine transfer across the human term placenta. 3. Johnson RF, Johnson HV, Arney TL, Paschall RL, Herman N, Downing JW. Society for Obstetric Anesthesia and perinatology. SOAP; Montreal, Canada. 1995 May; Sufentanil transfer across the human term placenta: the effect of fetal pH. 4. Downing JW, Johnson HV, Arney TL, Paschall RL, Dimowo JO, Johnson RF. Association of University Anesthesologist. AUA; 1996 May; The effects of ephedrine and phenylephrine on fetal perfusion pressure during in vitro placental perfusion. 5. Downing JW, Johnson HV, Arney TL, Paschall RL, Dimowo JO, Herman N, Johnson RF. Society for Obstetric Anesthesia and perinatology. SOAP; Tucson, Arizona. 1996 May; The effects of ephedrine ,phenylephrine and methoxamine on fetal perfusion pressure during in vitro placental perfusion. 6. Downing JW, Johnson HV, Arney TL, Paschall RL, Dimowo JO, Herman N, Johnson RF. Society for Obstetric Anesthesia and perinatology. SOAP; Tucson, Arizona. 1996 May; The effects of fetal pH and maternal protein binding on local anesthetic transfer across the human term placenta. 7. Sastry BVR, Ramasubramanian R, Arney TL, Paschall RL, Minzter BH, Johnson RF, Downing JW. Association of University Anesthesologist. AUA; 1997 May; The effects of halothane on the placental hypoxic vasoconstrictor response (PHVR). 8. Sastry BVR, Hemontolor ME, Johnson RF. Association of University Anesthesologist. AUA; 1997 May; Influence of bupivacaine on the prostaglandin E2 of F2-induced ppressor responses in perfused human placental cotyledon. 9. Downing JW, Herman NL, Arney TL, Paschall RL, Minzter BH, Olenick M, Ramasubramanian R, Johnson RF. Society for Obstetric Anesthesia and perinatology. SOAP; Bermuda. 1997 May; The placental hypoxic vasoconstrictor response (PHVR). 10. Johnson RF, Arney TL, Paschall RL, Minzter BH, Olenick M, Ramasubramanian R, Gonzalez H, Downing JW. Society for Obstetric Anesthesia and perinatology. SOAP; Bermuda. 1997 May; A comparison of the placental transfer of ropivacaine versus bupivacaine. 11. Downing JW, Olenick M, Paschall RL, Minzter BH, Ramasubramanian R, Arney TL, Herman NL, Johnson RF. Society for Obstetric Anesthesia and perinatology. SOAP; Bermuda. 1997 May; The effects of halothane on the placental hypoxic vasoconstrictor response (PHVR). 12. Downing JW, Olenick M, Paschall RL, Minzter BH, Ramasubramanian R, Arney TL, Johnson RF. Society for Obstetric Anesthesia and perinatology. SOAP; 1998 May; The effects of isoflurane on the placental hypoxic vasoconstrictor response (PHVR). 13. Johnson RF, Olenick M, Paschall RL, Minzter BH, Ramasubramanian R, Arney TL, Downing JW. Society for Obstetric Anesthesia and perinatology. SOAP; 1998 May; Epinephrine and the perfused human placenta. 14. Downing JW, Olenick M, Paschall RL, Minzter BH, Ramasubramanian R, Arney TL, Herman NL, Johnson RF. Association of University Anesthesologist. AUA; 1998 May; Theeffects of isoflurane on the placental hypoxic vasoconstrictor response (PHVR). 15. Downing JW, Olenick M, Paschall RL, Minzter BH, Ramasubramanian R, Arney TL, Johnson RF. Association of University Anesthesologist. AUA; 1998 May; Epinephrine does not effect intra villous vascular resistance (FIVR) and displays limited transfer across the human placenta. 16. Johnson RF, Minzter BH, Paschall RL, Ramasubramanian R, Downing JW. Association of University Anesthesologist. AUA; 1999 May; Norepinephrine transfer across the dual perfused human placenta. 17. Cahana A, Johnson RF, Minzter BH, Paschall RL, Ramasubramanian R, Downing RF. Association of University Anesthesologist. AUA; 1999 May; Transfer of gabapentin across the dual perfused human placental cotyledon. 18. Johnson RF, Minzter BH, Paschall RL, Ramasubramanian R, Downing JW. Society for Obstetric Anesthesia and perinatology. SOAP; 1999 May; Norepinephrine transfer across the dual perfused human placenta. 19. Cahana A, Johnson RF, Minzter BH, Paschall RL, Ramasubramanian R, Downing RF. Society for Obstetric Anesthesia and perinatology. SOAP; 1999 May; Transfer of gabapentin across the dual perfused human placental cotyledon. 20. Johnson RF, Minzter BH, Paschall RL, Ramasubramanian R, Downing JW. International Meeting of World Placenta Associations. IFPA; Schladming, Austria. 1999 Sep; Transfer of gabapentin across the dual perfused human placental cotyledon. 21. Johnson RF, Sastry Rama BV, Downing JW. International Meeting of World Placenta Associations. IFPA; Schladming, Austria. 1999 Sep; Norepinephrine transfer across the dual perfused human placenta. 22. Downing JW, Ramasubramanian R, Minzter BH, Paschall RL, York J, Johnson RF. Association of University Anesthesologist. AUA; 2000 May; Response of the fetoplacental vasculature to graded hypoxia: a study using the isolated, dual perfused, single human placental cotyledon. 23. Downing JW, Ramasubramanian R, Minzter BH, Paschall RL, York J, Johnson RF. Association of University Anesthesologist. AUA; 2001 May; Phosphodiesterase (PDE5) receptor inhibition obtunds the vasopressor actions of 5-HT on the placental intravillous circulation. 24. Downing JW, Ramasubramanian R, Minzter BH, Paschall RL, Lockhart E, Johnson B, Johnson RF. Association of University Anesthesologist. AUA; Nashville, Tennessee. 2002 May; Sodium nitroprusside inhibits hypoxic feto-placental vasoconstriction in the dual perfused, single isolated human placental cotyledon. 25. Downing JW, Ramasubramanian R, Minzter BH, Paschall RL, Lockhart E, Johnson B, Johnson RF. Society for Obstetric Anesthesia and perinatology. SOAP; Hilton Head, South Carolina. 2002 May; Sodium nitroprusside inhibits hypoxic feto-placental vasoconstriction in the dual perfused, single isolated human placental cotyledon. 26. Moore MC, DiCostanzo CA, Johnson RF, Farmer B, Neal DW, Hastings J, Cherrington AD. American Diabetes Association Meeting. ADA; 2002 Jun; A selective serotonin reuptake inhibitor (SSRI) enhances net hepatic uptake (NHGU). 27. Moore MC, DiCostanzo CA, Converse C, Scott M, Johnson RF, Everett CW, Neal DW, Cherrington AD. American Diabetes Association Meeting. ADA; 2002 Jun; Sites of serotonin release during duodenal glucose infusion. 28. Agawal HS, Johnson RF, Blakely RF. Genetics Symposium. Meharry Medical College; Nashville, Tennessee. 2003 Sep; Study of polymorphisms in serotonin transporter in familial primary pulmonary hypertension. 29. Prasad HC, Henry KL, Johnson RF, Malone D, Mertz RC, Shelton RC, Blakely RD. Genetics Symposium. Meharry Medical College; Nashville, Tennessee. 2003 Sep; Serotonin transporter gene (SLAC6A4) heterogeneity in human disorders: functional evaluation of coding mutants and exploration of novel SERT variants in depression and irritable bowel syndrome.