NAGLU monoclonal antibody (M02), clone 1B7

Catalog # : H00004669-M02 規格 : [ 100 ug ] List All

Specification Application Image

Product Mouse monoclonal antibody raised against a partial recombinant Western Blot (Cell lysate) Description: NAGLU.

Immunogen: NAGLU (NP_000254, 644 a.a. ~ 742 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Sequence: YQLTLWGPEGNILDYANKQLAGLVANYYTPRWRLFLEALVDSVAQGIPF QQHQFDKNVFQLEQAFVLSKQRYPSQPRGDTVDLAKKIFLKYYPGWVA enlarge GS Western Blot (Recombinant protein) Host: Mouse Sandwich ELISA (Recombinant Reactivity: Human, Mouse protein) ELISA Isotype: IgG2a Kappa

Quality Control Antibody Reactive Against Recombinant Protein. Testing:

Western Blot detection against Immunogen (36.63 KDa) .

Storage Buffer: In 1x PBS, pH 7.4

Storage Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing. Instruction:

MSDS: Download

Datasheet: Download

Applications

Western Blot (Cell lysate)

Page 1 of 3 2016/5/21 NAGLU monoclonal antibody (M02), clone 1B7. Western Blot analysis of NAGLU expression in NIH/3T3. Protocol Download

Western Blot (Recombinant protein) Protocol Download

Sandwich ELISA (Recombinant protein) Detection limit for recombinant GST tagged NAGLU is approximately 30ng/ml as a capture antibody. Protocol Download

ELISA

Gene Information

Entrez GeneID: 4669

GeneBank NM_000263 Accession#:

Protein NP_000254 Accession#:

Gene Name: NAGLU

Gene Alias: MPS-IIIB,MPS3B,NAG,UFHSD

Gene N-acetylglucosaminidase, alpha- Description:

Omim ID: 252920, 609701

Gene Ontology: Hyperlink

Gene Summary: This gene encodes an enzyme that degrades heparan sulfate by hydrolysis of terminal N-acetyl-D-glucosamine residues in N-acetyl- alpha-D-glucosaminides. Defects in this gene are the cause of mucopolysaccharidosis type IIIB (MPS-IIIB), also known as Sanfilippo syndrome B. This disease is characterized by the lysosomal accumulation and urinary excretion of heparan sulfate. [provided by RefSeq

Other N-acetyl-alpha-glucosaminidase,alpha-N-acetylglucosaminidase Designations:

Gene Pathway Glycosaminoglycan degradation Lysosome Metabolic pathways

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