Status of the Artificial Heart Program
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The First Total Artificial Heart
The First Total Artificial Heart On the night of December 1-2, 1982, with a major winter storm howling outside, medical history was being made inside the University of Utah Hospital. This event was the implantation of the first destination total artificial heart (TAH) in a human being. That person, 61-year-old Barney Clark, was a retired Seattle dentist with family roots in Utah. Dr. Clark’s several year history of dyspnea and fatigability had been attributed to chronic obstructive pulmonary disease in a University of Utah Hospital former smoker. However, 2 1/2 years before admission, a diagnosis of heart failure was made associated with atrial fibrillation with a rapid ventricular response. In-patient treatment for recurrent heart failure with paroxysmal ventricular tachycardia (VT) was required 1 ½ years before admission. Coronary angiography and left ventriculography established a diagnosis of advanced, non-ischemic dilated cardiomyopathy with an ejection fraction of 23%. Because of symptomatic progression of heart failure, Dr. Clark was referred to the author at LDS Hospital in Salt Lake City, near family members, for investigational inotrope therapy (amrinone), but this caused hypotension and exacerbated atrial and ventricular tachyarrhythmias. Endomyocardial biopsy showed low-grade cellular and humoral myocarditis, and a course of immunosuppressant therapy (prednisone and azathioprine) was begun with initial improvement. However, clinical deterioration resumed, with low- output failure and edema, 6 ½ months later, leading to hospitalization for IV diuretics and dobutamine. Clinical improvement was only marginal, leaving him in class IV heart failure. Jeffrey L. Anderson, MD: Barney Clark’s Cardiologist An opportune meeting occurred 3-4 months prior to the final admission between the author and Dr. -
2014 FP 1-78:4-Color Section
FINAL PROGRAM 34th Annual Meeting and Scientific Sessions April 10 – 13, 2014 MANCHESTER GRAND HYATT SAN DIEGO International Society for Heart and Lung Transplantation Gilead is committed to expanding healthcare options for individuals living with cardiovascular and pulmonary diseases through innovative research, access, and education programs. © 2013 Gilead Sciences, Inc. All rights reserved. UNBP0009 March 2013 Gilead and the Gilead logo are trademarks of Gilead Sciences, Inc. INTERNATIONAL SOCIETY FOR HEART AND LUNG TRANSPLANTATION 34th ANNUAL MEETING and SCIENTIFIC SESSIONS April 10 – 13, 2014 TABLE OF CONTENTS About ISHLT 2 Board of Directors 4 Scientific Program Committee 6 Abstract Reviewers 8 Committees 17 Scientific Councils 25 Past Presidents 32 Daily Schedule Foldouts between 34-47 Award Recipients 35 Continuing Medical Education 46 Annual Meeting 49 Scientific Session Highlights Manchester Grand Hyatt Floor Plans 64 Annual Meeting 67 Schedule At a Glance Corporate Partners 78 Annual Meeting 79 Scientific Program and Schedule Exhibit Hall Floor Plan 278 List of Exhibitors 280 1 2 THE INTERNATIONAL SOCIETY FOR HEART AND LUNG TRANSPLANTATION (ISHLT) is a not-for-profit, multidisciplinary, professional organization dedicated to improving the care of patients with advanced heart or lung disease through transplantation, mechanical support and innovative therapies via research, educa- tion and advocacy. ISHLT was created in 1981 at a small gathering of The about 15 cardiologists and Purposes cardiac surgeons. Today we of the have over 2700 members from over 45 countries, rep- Society resenting over 15 different are: professional disciplines in- 1. To associate persons volved in the management interested in the fields of heart and treatment of end-stage and lung transplantation, end- heart and lung disease. -
Johns Hopkins, Building a Better Heart
In 1982 William DeVries, a cardiac surgeon at the University of Utah Hospital, successfully implanted an artificial heart in a patient who was suffering from end-stage heart failure. The recipient lived for 112 days with the device, designed by Robert Jarvik. Thirty years later, we've cloned sheep, developed the Internet, mapped the human genome, and progressed from LPs to CDs to MP3s, but we still haven't created an artificial heart that can sustain life for longer than a few months. "If you think about technologies in general and how they've advanced in the past three decades, I don't think you'd say that artificial heart technology has progressed at a pace that's appropriate for the amount of time that has passed," says T.E. "Ed" Schlesinger, dean of Johns Hopkins' Whiting School of Engineering. So what's the holdup? The challenges of creating an artificial heart that can "beat" an average of 35 million times a year for multiple years like a real heart are myriad. There are problems to solve regarding biocompatibility, power supply, blood flow, pumping systems, control mechanisms. Should the heart be fabricated from synthetic materials, muscle tissue grown from stem cells, or a combination of both? Does it have to pump like a real heart, or should it rely on a system of continuous flow, as current heart-assist devices do? Last winter, more than 160 people from the Johns Hopkins community and beyond attended the first Hopkins Heart Symposium. The purpose was to kick off a 10-year, $100 million-plus collaboration between doctors, engineers, and systems experts at Johns Hopkins to build the world's first permanent totally artificial heart. -
Decrease in Driveline Infections with Change in Driveline Management Protocol
View metadata, citation and similar papers at core.ac.uk brought to you by CORE provided by University of Kentucky The VAD Journal: The journal of mechanical assisted circulation and heart failure Peer-Reviewed Original Research Decrease in Driveline Infections with Change in Driveline Management Protocol Saima Aslam*, Jennifer Dan, Amanda Topik, Michael Belyk, Francesca Torriani, Randy Taplitz, Jorge Silva-Enciso, Denise Barnard, Barry Greenberg, Jack Copeland, Victor Pretorius, Eric Adler University of California, San Diego, CA * Corresponding author: [email protected] Citation: Aslam, S. et al. (2016)."Decrease in Driveline Abstract Infections with Change in Driveline Management Protocol” Background The VAD Journal, 2. doi: http://dx.doi.org/10.13023/VAD. Driveline infections (DLI) are a significant cause of morbidity and mortality in 2016.03 ventricular assist device (VAD) recipients. We compared driveline infection (DLI) Editor-in-Chief: Maya Guglin, rate after an institutional change in driveline management protocol. University of Kentucky Received: February 9, 2016 Methods Accepted: February 20, 2016 We retrospectively reviewed records of left VAD recipients at our institution, Published: March 3, 2016 based on driveline management. Group 1: daily driveline dressing change © 2016 The Author(s). This is an consisting of chlorhexidine cleansing, sterile 4x4 gauze, and use of an abdominal open access article published under the terms of the Creative binder. Group 2: Dressing change every 3 days consisting of chlorhexidine Commons Attribution- cleansing, non-sterile silver-impregnated foam with overlying clear dressing, and NonCommercial 4.0 International License use of a driveline anchor. Follow-up was censored at first DLI, device removal, (https://creativecommons.org/lice transplant or death. -
Sarver Heart Center Winter 2016-2017
Sarver Heart Center NEWSLETTER ISSUE 74 • WINTER 2016-2017 UA SARVER HEART CENTER’S 30 YEARS OF PROGRESS: 4 30 Years of Progress BUILDING ON A PROUD HISTORY Saving Hearts with Technology - In 1985, the year before University Heart Center 6 Member Updates was established, Jack G. Copeland, MD, became the first surgeon to successfully use an artificial heart as a bridge to heart transplant. The artificial heart replaced 8 Investigator Awards the diseased heart of an end-stage heart failure patient, Michael Drummond, saving his Zain Khalpey, MD, PhD, cardiothoracic surgery, and Jennifer Cook, MD, life while he waited for cardiology, collaborate as the surgical and medical directors of the a donor heart. Mechanical Circulatory Support Program to provide heart failure patients with quality-of-life-improving devices that typically extend life for years, Today, heart failure 13 Mary Anne Fay, when traditional medical therapies aren’t working. (HF) affects about 5 Dedicated Supporter million people in the United States and about 250,000 people die each year from HF. Cardiologists have learned a RAT lot during the past 30 years about how to improve a person’s odds of living longer with HF, EB IN L G E while maintaining a better quality of life, even after traditional medical therapies have failed. C } Advanced heart failure and transplant cardiologists care for HF patients who are out of options. } Years } } } } } What was just a few years ago the end of the line, is no longer. Heart transplantation, artificial 6 heart pumps, specialized pacemakers and new and better drugs are making a difference. -
INFORMED CONSENT to the ARTIFICIAL HEART George J
Western New England Law Review Volume 9 9 (1987) Article 7 Issue 1 1-1-1987 DEATH AND THE MAGIC MACHINE: INFORMED CONSENT TO THE ARTIFICIAL HEART George J. Annas Follow this and additional works at: http://digitalcommons.law.wne.edu/lawreview Recommended Citation George J. Annas, DEATH AND THE MAGIC MACHINE: INFORMED CONSENT TO THE ARTIFICIAL HEART, 9 W. New Eng. L. Rev. 89 (1987), http://digitalcommons.law.wne.edu/lawreview/vol9/iss1/7 This Article is brought to you for free and open access by the Law Review & Student Publications at Digital Commons @ Western New England University School of Law. It has been accepted for inclusion in Western New England Law Review by an authorized administrator of Digital Commons @ Western New England University School of Law. For more information, please contact [email protected]. DEATH AND THE MAGIC MACHINE: INFORMED CONSENT TO THE ARTIFICIAL HEARTt GEORGE J. ANNAS· INTRODUCTION Jay Katz introduces his remarkable and insightful book, The Si lent World of Doctor and Patient,1 by recounting a portion of Solzhenitsyn's Cancer Ward. 2 He describes an encounter between a patient, Oleg Kostoglotov, and his doctor, Dr. Ludmilla Afanasyevna. The doctor wanted to use experimental hormone treatment, but the patient refused. Katz argues that what made conversation impossible between them was the patient's undisclosed intention of leaving the hospital to treat himself with "a secret medicine, a mandrake root from Issyk Kul." He could not trust the doctor with this information because the doctor would make the decision for the patient in any event, because the doctor believed, "doctors are entitled to that right .. -
State /National
state /national Battalion/Page 7A December 6, 1982 embeffii Media reps to meet Artificial heart implanted, with Hispanic leaders patient’s doctors optimistic United Press International American Citizens, said rep a need to provide the Hispa SAN DIEGO, Texas — His- resentatives of the television nic viewpoint.” United Press International remained cautious about Clark’s healing process. trauma and still has some I panic leader Tony Bonilla industry agreed to the confer Bonilla said the coalition of SALT LAKE CITY — Barney long-term outlook. Their prim Jarvik said a sac of connective pathology present,” she said. I said a committee of about 50 ence during a meeting in New groups is monitoring the por Clark was taken off the critical ary concern was infection, tissue must form around the Jarvik said one surprise was 1 groups will meet next month York last Thursday. trayal of Hispanics nation list Saturday in a major step in ,although the latest report said artificial heart, in addition to the ease with which Clark could I with television network repre- “For the time being there wide and keeping track of his recovery from the world’s there was no evidence of that healing of the chest incision. be cared for, compared to the Isentatives to air complaints will be no boycott,” Bonilla media handling of Hispanic first implantation of a perma developing. This is called a pseudo usual person recovering from [about media stereotyping of said Friday. “The networks issues. nent artificial heart two days “I think infection is the short pericardium and helps hold the heart surgery. -
Thoracic and Cardiovascular Surgery
GREAT INSTITUTIONS One Hundred Years of History at Stanford University: Thoracic and Cardiovascular Surgery Y. Joseph Woo, MD, and Bruce A. Reitz, MD The history of thoracic and cardiovascular surgery at Stanford spans a century long period, beginning not long after the founding of Stanford University. Pioneering Stanford surgeons have made landmark discoveries and innovations in pulmonary, transplantation, thoracic aortic, mechanical circulatory support, minimally invasive, valvular, and congenital heart surgery. Fundamental research formed the foundation underlying these and many other advances. Educating and training the subsequent leaders of cardio- thoracic surgery has throughout this century-long history constituted a mission of the highest merit. New Stanford Adult Hospital Semin Thoracic Surg 27:388–397 I 2015 Elsevier Inc. All rights reserved. Central Message Keywords: History, Cardiovascular Surgery, Thoracic Surgery, Transplantation, Aortic Dissection Stanford: Upon a foundation of rigorous scien- tific investigation and dedicated teaching, Stan- ford thoracic and cardiovascular surgeons PRE-STANFORD UNIVERSITY Stanford Faculty in pioneered discoveries and innovations in pul- Lineage tracing of the history of Stanford Cardiothoracic 1914 and led the monary, transplantation, aortic, minimally inva- Surgery could be extended back to 1857, even before the Stanford surgical sive, and congenital heart surgery. founding of Stanford University. Elias Samuel Cooper, a San service at the San Francisco surgeon, authored “Report of an Operation to Francisco General Hospital2 (Fig. 2). Although he practiced a Remove a Foreign Body from Beneath the Heart” published broad spectrum of surgery, much of his clinical and experimental by the San Francisco Medico Chirurgical Association. The work and scholarly publications were in the arena of chest following year in 1858, Cooper founded the first medical surgery. -
Instrumental Reason and the Artificial Heart Experiment
disClosure: A Journal of Social Theory Volume 5 Reason INCorporated Article 5 4-15-1996 Plastic Heart, Black Box, Iron Cage: Instrumental Reason and the Artificial Heart Experiment Thomas Strong Princeton University DOI: https://doi.org/10.13023/DISCLOSURE.05.05 Follow this and additional works at: https://uknowledge.uky.edu/disclosure Part of the Anthropology Commons This work is licensed under a Creative Commons Attribution-Noncommercial 4.0 License. Recommended Citation Strong, Thomas (1996) "Plastic Heart, Black Box, Iron Cage: Instrumental Reason and the Artificial Heart Experiment," disClosure: A Journal of Social Theory: Vol. 5 , Article 5. DOI: https://doi.org/10.13023/DISCLOSURE.05.05 Available at: https://uknowledge.uky.edu/disclosure/vol5/iss1/5 This Article is brought to you for free and open access by disClosure: A Journal of Social Theory. Questions about the journal can be sent to [email protected] 28 Thomas Strong Plastic Heart, Black Box, Iron Cage 29 Plastic Heart, Black Box, Iron Cage: Instrumental Reason and the Artificial Heart Experiment• ·by Thomas Strong Department of Anthropology, Princeton University The heart has reasons which reason knows not. Pascal On the night of December 1, 1982, a surgical team in Salt Lake City implanted a plastic pump in the chest of 61 year old Barney Clark. The operation lasted nine hours; it was not without complications. It was the first time in history that a human being had been implanted with an "artificial heart" intended as a permanent re placement for his "real" heart. Clark died 112 days later on the night of March 23, 1983: his circulatory system had collapsed. -
Mechanical Circulatory Support in End-Stage Heart Failure
Mechanical Circulatory Support in End-Stage Heart Failure Andrea Montalto Antonio Loforte Francesco Musumeci Thomas Krabatsch Mark S. Slaughter Editors Mechanical Circulatory Support in End-Stage Heart Failure A Practical Manual In collaboration with Cristiano Amarelli Editors Andrea Montalto Thomas Krabatsch San Camillo-Forlanini Hospital Deutsches Herzzentrum Berlin Rome, Italy Berlin, Germany Antonio Loforte Mark S. Slaughter Cardiac Surgery Department of Cardiovascular S.Orsola-Malpighi Hospital and Thoracic Surgery Bologna, Italy University of Louisville Louisville, KY, USA Francesco Musumeci San Camillo-Forlanini Hospital Rome, Italy ISBN 978-3-319-43381-3 ISBN 978-3-319-43383-7 (eBook) DOI 10.1007/978-3-319-43383-7 Library of Congress Control Number: 2017943505 © Springer International Publishing Switzerland 2017 This work is subject to copyright. All rights are reserved by the Publisher, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilms or in any other physical way, and transmission or information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed. The use of general descriptive names, registered names, trademarks, service marks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. The publisher, the authors and the editors are safe to assume that the advice and information in this book are believed to be true and accurate at the date of publication. Neither the publisher nor the authors or the editors give a warranty, express or implied, with respect to the material contained herein or for any errors or omissions that may have been made. -
Batteries Included: Heart Patient Goes Home with Lifesaving Device
Batteries Included: Heart Patient Goes Home with Lifesaving Device November 1, 2010 Jackie Carr On Friday, October 15th, Bradley Cantley, 41, headed home from UC San Diego Medical Center connected to a lifesaving heart machine called a left ventricular assisted device (LVAD). For patients with advanced heart failure, the mechanical pump rapidly improves circulation throughout the body and serves as a bridge to transplant. Cantley is the first of many patients, locally and globally, who will benefit from the expanded heart surgery program at UC San Diego Health System. "Left ventricular assisted devices bring healing, oxygen-rich blood to all the organs of the body," said Jack Copeland, MD, professor of surgery and director of cardiac transplantation and mechanical circulatory support at UC San Diego Health System. "Some patients recover with these implantable devices because the heart is able to rest and recuperate. Others keep the LVAD until a donor heart becomes available." Cantley attributes his heart disease to obesity. He weighed 358 pounds at the time of his heart attack and has since lost more than 200 pounds. "Prior to the heart pump I was so short of breath I would have to take intermittent breaks just to breathe in," said Cantley. "Now I can get up and walk around without huffing and without having to steady myself. I can see the improvement." Heart failure, if untreated, leads to a slow process of starvation and suffocation. The liver is unable to produce proteins; the kidney does not eliminate toxins, and the digestive system cannot absorb nutrition. Due to retention of fluids, breathing and mobility also become limited. -
Preliminary Program
INTERNATIONAL SOCIETY FOR HEART AND LUNG TRANSPLANTATION Twenty-Second Annual Meeting and Scientific Sessions Final Program April 10-13, 2002 Convening at the Hilton Washington and Towers, Washington, DC PRESIDENT James B. Young, MD, Cleveland, OH PRESIDENT-ELECT Stephan Schueler, MD, Newcastle Upon Tyne, United Kingdom PAST PRESIDENT Anne Keogh, MBBS, MD, Sydney, Australia SECRETARY/TREASURER Alec Patterson, MD, St. Louis, MO DIRECTORS Robert C. Bourge, MD, Birmingham, AL Paul A. Corris, MB, FRCP, Newcastle Upon Tyne, United Kingdom F. Jay Fricker, MD, Gainesville, FL Axel Haverich, MD, Hannover, Germany Luigi Martinelli, MD, Genova, Italy Mehmet C. Oz, MD, New York, NY Sabina M. De Geest, RN, PhD, Basel, Switzerland W. Steves Ring, MD, Dallas, TX Robert C. Robbins, MD, Stanford, CA David O. Taylor, MD, Cleveland, OH Adriana Zeevi, PhD, Pittsburgh, PA JHLT EDITOR James K. Kirklin, MD, Birmingham, AL HEART AND LUNG TRANSPLANT REGISTRY MEDICAL DIRECTOR Marshall I. Hertz, MD, Minneapolis, MN MECHANICAL CIRCULATORY SUPPORT DEVICE DATABASE MEDICAL DIRECTOR Mario Deng, MD, New York, NY STAFF Amanda W. Rowe, Executive Director Phyllis Glenn, Director of Membership Services Lisa Edwards, Director of Meetings LeeAnn Mills, Director of Operations 14673 Midway Road, Suite 200 Addison, TX 75001 Phone: 972-490-9495 Fax: 972-490-9499 www.ishlt.org [email protected] INTERNATIONAL SOCIETY FOR HEART AND LUNG TRANSPLANTATION PAST PRESIDENTS 1981-1982 Michael Hess, MD 1982-1984 Jack Copeland, MD 1984-1986 Terence English, FRCS 1986-1988 Stuart Jamieson, MD 1988-1990 Bruno Reichart, MD 1990-1991 Margaret Billingham, MD 1991-1992 Christian Cabrol, MD 1992-1993 John O’Connell, MD 1993-1994 Eric Rose, MD 1994-1995 John Wallwork, FRCS 1995-1996 Sharon Hunt, MD 1996-1997 William Baumgartner, MD 1997-1998 Leslie Miller, MD 1998-1999 Alan Menkis, MD, FRCS(C) 1999-2000 Robert L.