Authors: Pallavi Subhraveti Ron Caspi Peter Midford Peter D Karp An online version of this diagram is available at BioCyc.org. Biosynthetic pathways are positioned in the left of the cytoplasm, degradative pathways on the right, and reactions not assigned to any pathway are in the far right of the cytoplasm. Transporters and membrane proteins are shown on the membrane. Ingrid Keseler Periplasmic (where appropriate) and extracellular reactions and proteins may also be shown. Pathways are colored according to their cellular function. Gcf_900070365Cyc: Alloactinosynnema sp. L-07 Cellular Overview Connections between pathways are omitted for legibility. Anamika Kothari molybdate N-acetyl-α-D-glucosamine N,N'-diacetylchitobiose predicted ABC NgcE transporter of molybdate

N-acetyl-α-D-glucosamine N,N'-diacetylchitobiose molybdate

Amino Acid Degradation Degradation/ F0F1 ATP H + H + Aminoacyl-tRNA Charging glutaminyl-tRNA gln Macromolecule Modification tRNA processing Utilization/ synthase a [2-oxoglutarate dehydrogenase E2 hydrogen a [protein]- UDP-N-acetyl- 7,8- (4R)-4-hydroxy- biosynthesis via transamidation Assimilation - Other menadione NADH H + a reduced a holo [D-alanyl an L-cysteinyl- L-isoleucine degradation I 6 adenosylcobinamide a purine FAD α carbonic acid NADH L-arginine degradation L-tryptophan degradation to 2-amino- protein] N -dihydrolipoyl-L-lysine peroxide L-threonine -D-muramoyl- dihydroneopterin 2-oxoglutarate D-ala met Pro a polycistronic L-leucine degradation I acrylonitrile ribonucleoside thioredoxin carrier protein] [tRNA ] XIII (reductive 3-carboxymuconate semialdehyde 2-oxoglutarate L-alanyl-γ-D- 2',3'-cyclic a reduced glu tRNA precursor degradation I 5'-triphosphate bifunctional Stickland reaction) dehydrogenase, glutamyl-meso-2,6- phosphate polyprenol glutamate N- H O c-type ile NADH-quinone FAD:protein FMN bifunctional bifunctional SulP NAD(+) 2 leu E2 component, peroxiredoxin: diaminopimeloyl- phosphomannose- cysteine--1-D-myo- acetyltransferase/ Cys- cytochrome trp acrylonitrile bifunctional oxidoreductase: nuoN transferase: 4-hydroxy-2- family inorganic diphosphatase: CtaD an oxidized branched-chain arg dihydrolipoamide BN1701_RS32750 D-alanyl-D-alanine dependent alpha 1,6 inosityl 2-amino- amino-acid tRNA(Pro) branched-chain tryptophan 2,3- adenosylcobinamide BN1701_RS23795 nuoK BN1701_RS01405 oxoglutarate anion transporter/ nudC O c-type succinyltransferase: sucB 2 amino acid amino acid arginine deiminase: thioredoxin- mannosyltransferase aldolase/2- 2-deoxy-alpha-D- acetyltransferase deacylase: a reduced a tRNA precursor dioxygenase: L-asparagine kinase/ BN1701_RS23810 nuoI FAD:protein FMN carbonic anhydrase: NAD(+) cytochrome gln ribonuclease D: aminotransferase: BN1701_RS27110 multifunctional oxoglutarate dependent D-alanyl-D-alanine MptB: mptB glucopyranoside ArgJ: argJ ybaK H O c-type an L-glutamyl- aminotransferase: BN1701_RS08190 adenosylcobinamide- nuoH BN1701_RS23825 dehydro-3-deoxy- BN1701_RS16275 2 with a 5' extension BN1701_RS03250 degradation I acrylamide thiol transferase: diphosphatase: cytochrome Gln BN1701_RS04220 BN1701_RS03250 L-citrulline decarboxylase/oxoglutarate carboxypeptidase/ polyprenol phosphogluconate ligase: amino-acid N- cytochrome [tRNA ] and a long 3' trailer tryptophan 2,3- phosphate nuoF nuoE BN1701_RS26705 carbonic anhydrase: nudC c oxidase an oxidized pyridoxal 5'- a tRNA precursor with branched-chain amidase: dehydrogenase thiamine peroxidase: D-alanyl-D-alanine- phosphomannose- aldolase: eda BN1701_RS11265 acetyltransferase: Asp-tRNA(Asn) branched-chain dioxygenase: guanylyltransferase: BN1701_RS23840 BN1701_RS28700 O c-type phosphate a 5' extension and ornithine asn pyrophosphate-binding bcp endopeptidase: dacB a tRNA Pro 2 ribonuclease amino acid amino acid BN1701_RS13865 BN1701_RS03505 BN1701_RS03265 BN1701_RS23845 dependent alpha 1,6 BN1701_RS16210 β cys cytochrome synthase: /Glu-tRNA(Gln) a short 3' extension N-Formyl-L- asparaginase: a [protein]-FMN- reduced - a sugar RS13515 a sugar PH: rph aminotransferase: carbamoyltransferase: [+ 2 isozymes] subunit/dihydrolipoyllysine- BN1701_RS23855 mannosyltransferase a D-alanyl- N-acetyl-L- amidotransferase: ribonuclease aminotransferase: kynurenine BN1701_RS14170 adenosyl- nicotinamide D- pdxT pdxS polyribonucleotide BN1701_RS08345 BN1701_RS10680 residue succinyltransferase AMP L-threonine 7,8- MptB: mptB [D-alanyl methionine AMP gatB gatA gatC ribonuclease D: P protein BN1701_RS08345 4-methyl-2- cobinamide an oxidized H O UDP-N- glyoxylate pyruvate CO H O ribonucleotide [+ 15 isozymes] ribonuclease D: kynurenine [+ 3 isozymes] acrylate subunit: BN1701_RS21585 2 dihydroneopterin 2 2 a 5-phosphooxy- BN1701_RS04220nucleotidyltransferase: component: (3S)-3-methyl-2- oxopentanoate ornithine phosphate a purine thioredoxin D-ala acetylmuramoyl- carrier protein] BN1701_RS04220 formamidase: asp a [2-oxoglutarate dehydrogenase E2 2'-phosphate a sugar RS13735 a sugar L-glutamyl- BN1701_RS16430 carbamoyltransferase: ribonucleoside NAD + menadiol L-alanyl-γ-D- ammonium rnpA oxopentanoate BN1701_RS08195 protein] N 6 -S-succinyldihydrolipoyl-L-lysine [tRNA Gln ] argF 5'-diphosphate glutamyl-meso-2,6- a tRNA precursor with diaminopimeloyl- L-kynurenine Asp-tRNA(Asn) a short 3' extension 3-methylbutanoyl- L-ornithine D-alanine a sugar RS30815 a sugar (2S)-2- CoA /Glu-tRNA(Gln) a tRNA precursor kynurenine 3- amidotransferase: methylbutanoyl- isovaleryl-CoA ornithine- with a 5' extension CoA -oxo-acid monooxygenase: a mature peptidoglycan a DNA containing 7,8- 3-oxo-23,24- a [DNA]-3'- a 5'-phospho- 3-oxo-23,24- a peptide with gatB gatA gatC ribonuclease ribonuclease D: dehydrogenase: H + hydrogencarbonate carbamoyl a [glutamine- 2-methylbutanoyl- BN1701_RS33700 (meso-diaminopimelate an apurinic/ L-ornithine dihydroneopterin bisnorchol-1,4- bisnorchol-4- an N-terminal ser a tRNA sec BN1701_RS21480 transaminase: dGTP ATP hydroxyl [DNA] ATP roseoflavin predicted PH: rph BN1701_RS04220 containing) apyrimidinic site phosphate synthetase]- 2',3'-cyclic dien-22-yl-CoA en-22-oyl-CoA L-methionine ribonuclease CoA dehydrogenase: rocD 3-hydroxy- 3-ketosteroid-9- 3-ketosteroid-9- 5'-phosphate ABC an L-glutaminyl- 3-methylcrotonyl- L-tyrosine phosphate a sugar a sugar P protein BN1701_RS21480 L-kynurenine polyprenol alpha-hydroxylase alpha-hydroxylase transporter [tRNA Gln ] (E)-2- CoA L-glutamate-5- bifunctional SulP non- component: semialdehyde endolytic endonuclease ornithine phosphomannose- subunit A: subunit A: type I methionyl serine- of a sugar methylcrotonoyl- acetyl/propionyl/ kynureninase: family inorganic homologous bifunctional tRNA charging rnpA transglycosylase deoxyguanosinetriphosphate III: nth carbamoyltransferase: bifunctional [glutamine dependent alpha 1,6 BN1701_RS13065 BN1701_RS13065 aminopeptidase: -tRNA ATP biosynthesis CoA BN1701_RS13860 anion transporter/ end-joining methylcrotonyl- MltG: mltG triphosphohydrolase: BN1701_RS10680 synthetase] mannosyltransferase riboflavin kinase/ map ligase: predicted enoyl-CoA kynureninase: bifunctional DNA- carbonic anhydrase: 3-ketosteroid-9- DNA 3-ketosteroid-9- CoA carboxylase [+ 4 isozymes] BN1701_RS02805 adenylyltransferase/ MptB: mptB FAD synthetase: [+ 2 isozymes] serS ABC gly a tRNA Gly trp a tRNA Trp hydratase: formamidopyrimidine BN1701_RS16275 ornithine alpha-hydroxylase ligase: ligD alpha-hydroxylase a sugar a sugar ADP subunit alpha: kynU dNTP [glutamine synthetase]- BN1701_RS16450 transporter tyr Tyr thr Thr glu glu arg Arg cys Cys Met met Met met ile Ile phe Phe BN1701_RS23745 (S)-1-pyrroline- glycosylase/ carbamoyltransferase: polyprenol subunit A: subunit A: a tRNA a tRNA a tRNA a tRNA a tRNA elongator tRNA initiator tRNA a tRNA a tRNA F0F1 ATP synthase: BN1701_RS21485 triphosphohydrolase: dgt carbonic anhydrase: adenylyl-L-tyrosine [+ 4 isozymes] of a sugar Val His Ala asp Pro Leu ser Lys (2S,3S)-3- 5-carboxylate 3-hydroxyanthranilate a mature peptidoglycan a mature peptidoglycan DNA-(apurinic argF phosphomannose- α BN1701_RS21360 α BN1701_RS21360 val a tRNA his a tRNA a tRNA ala tRNA asp pro a tRNA leu a tRNA ser a tRNA lys a tRNA an uncharged tRNA BN1701_RS28700 phosphorylase: 9 -hydroxy-3-oxo- 9 -hydroxy- an L-seryl- Asn Gln BN1701_RS19330 [+ 2 isozymes] γ dependent alpha 1,6 roseoflavin glycine--tRNA ligase: tryptophan-- asn tRNA gln a tRNA hydroxy-2- pyrroline-5- with (L-alanyl- -D- strand (non- or apyrimidinic 23,24-bisnorchol- androst-4- met a peptide sec atpD BN1701_RS19360 3-methylglutaconyl- BN1701_RS31990 adenine [tRNA ] a sugar RS07130 a sugar tyrosine-- threonine-- glutamate-- arginine-- BN1701_RS20785 tRNA ligase: trpS cysteine-- methionine-- methionine-- isoleucine-- phenylalanine-- methylbutanoyl- carboxylate L-arginine degradation V glutamyl-meso-2,6- reducing terminus) site) lyase: mutM mannosyltransferase 1,4-dien-22-yl-CoA [DNA] en-3-one-17- BN1701_RS19365 CoA triphosphate 7,8- dinucleotide valine--tRNA ligase: histidine--tRNA tRNA ligase: alanine--tRNA aspartate--tRNA tRNA ligase: proline--tRNA ligase: tRNA ligase: tRNA ligase: glycine--tRNA ligase: tryptophan-- leucine--tRNA ligase: serine--tRNA lysine--tRNA tRNA ligase: tRNA ligase: tRNA ligase: tRNA ligase: tRNA ligase: pheS CoA reductase: (arginine deiminase pathway) diaminopimeloyl-D- 2'-deoxyguanosine CO H O L-citrulline MptB: mptB propanoyl-CoA BN1701_RS19370 2-amino-3- 2 2 a [glutamine dihydroneopterin BN1701_RS02005 ligase: hisS BN1701_RS14080 ligase: alaS ligase: aspS BN1701_RS14655 BN1701_RS16590 BN1701_RS18085 BN1701_RS19520 BN1701_RS02790 tRNA ligase: trpS BN1701_RS26450 ligase: serS ligase: lysS BN1701_RS28760 BN1701_RS30165 BN1701_RS30165 BN1701_RS32105 BN1701_RS06150 proC alanine) tetrapeptide BN1701_RS19375 carboxymuconate- a 3'-terminal a 5'-phospho- synthetase]-O 3'-phosphate lipoprotein posttranslational modification arg a sugar RS04020 a sugar BN1701_RS19380 atpB 6-semialdehyde unsaturated sugar [DNA] 4 -(5'-adenylyl) an L-methionyl- an L-methionyl- pro an L-valyl-[tRNA Val ] an L-histidyl-[tRNA His ] an L-tyrosyl-[tRNA Tyr ] an L-alanyl-[tRNA Ala ] an L-aspartyl-[tRNA asp ] an L-threonyl-[tRNA Thr ] an L-prolyl-[tRNA Pro ] an L-glutamyl-[tRNA Glu ] an L-arginyl-[tRNA Arg ] a glycyl-[tRNA Gly ] an L-tryptophanyl-[tRNA Trp ] an L-leucyl-[tRNA Leu ] an L-seryl-[tRNA ser ] an L-lysyl-[tRNA Lys ] an L-cysteinyl-[tRNA Cys ] an L-isoleucyl-[tRNA Ile ] an L-phenylalanyl-[tRNA Phe ] an L-asparaginyl-[tRNA Asn ] an L-glutaminyl-[tRNA Gln ] a [prolipoprotein]- 2-methylacetoacetyl- HMG-CoA -L-tyrosine [elongator tRNA Met ] [initiator tRNA Met ] ATP arginine deiminase: L-cysteine CoA hydroxymethylglutaryl- BN1701_RS27110 a sugar RS05060 a sugar prolipoprotein a ring-opened 7- 10 a [bis(guanylyl a peptide with a [glutamine 3-oxo-23,24- an N-terminal- an N-terminal- acetyl-CoA C- CoA lyase: an L-methionyl- an N - a lipid II 34 diacylglyceryl L-glutamate degradation methylguanine diphosphate H O synthetase]-O a glycyl-[tRNA Ala ] bisnorchol- L-methionyl-L- L-methionyl-L- a cytidine lys acetyl-CoA Met molybdopterin) cys 2 an N-terminal acyltransferase: BN1701_RS22180 L-citrulline [initiator tRNA ] formyltetrahydrofolate Ile2 transferase: VI (to pyruvate) in DNA 4 -(5'-adenylyl) 4-en-22-oate alanyl-[protein] valyl-[protein] in tRNA acetyl-CoA BN1701_RS03895 cofactor Xaa-L-proline 3-ketosteroid-9- Cofactor, Carrier, and Vitamin Biosynthesis a sugar RS11965 a sugar BN1701_RS01455 acetoacetate chaperone]- -L-tyrosine D-alanyl-D-alanine alpha-hydroxylase carboxylase biotin carboxyl prolipoprotein glu ornithine bifunctional DNA- methionyl-tRNA L-cysteine RdgB/HAM1 family leucyl carboxypeptidase/ D-tyrosyl-tRNA(Tyr) subunit A: type I methionyl type I methionyl tRNA acetyl-CoA propanoyl-CoA non-canonical deacylase: carrier mycofactocin biosynthesis [2Fe-2S] iron-sulfur adenosylcobinamide-GDP superpathway of thiamine diphosphate biosynthesis II diacylglyceryl L-tryptophan carbamoyltransferase: formamidopyrimidine formyltransferase: aminopeptidase: bifunctional [glutamine D-alanyl-D-alanine- BN1701_RS13065 aminopeptidase: aminopeptidase: lysidine(34) cob(II)yrinate a,c-diamide flavin biosynthesis I (bacteria and plants) thioredoxin protein: accB 2+ 2+ cob(II)yrinate a,c- transferase: degradation I glutamate mutase L: BN1701_RS10680 glycosylase/ BN1701_RS10490 purine NTP BN1701_RS03240 synthetase] endopeptidase: dacB BN1701_RS03935 map map synthetase Ni RS13715 Ni a C-terminal diamide biosynthesis I biosynthesis II (late cluster biosynthesis pathway salvage from cobinamide I cysteine desulfurase: 3-ketosteroid-9- BN1701_RS17730 (via anthranilate) BN1701_RS21895 DNA-(apurinic pyrophosphatase: adenylyltransferase/ [+ 2 isozymes] [+ 2 isozymes] TilS: tilS [+ 4 isozymes] [mycofactocin cobalt incorporation) a [ThiS sulfur- Aromatic Compound Biosynthesis ornithine methionyl-tRNA BN1701_RS18335 leucyl alpha-hydroxylase (early cobalt insertion) a [prolipoprotein]- or apyrimidinic rdgB [glutamine synthetase]- malonyl-CoA precursor L-cysteine desulfurase an oxidized cob(II)inamide carrier protein] (2S, 3S)-3- carbamoyltransferase: formyltransferase: [+ 2 isozymes] aminopeptidase: a N- subunit A: uroporphyrinogen-III GTP S-1,2-diacyl-sn- trp Ala uroporphyrinogen-III site) lyase: mutM [+ 2 isozymes] adenylyl-L-tyrosine a tRNA gly 34 2+ 2+ peptide]-glycyl-L- thioredoxin cob(I)yrinic acid L-histidine degradation I methylaspartate argF BN1701_RS14185 BN1701_RS31235 D-ala acetylglucosamine- 3-one-9-hydroxy-BN1701_RS21360 an N-terminal L- an N-terminal a lysidine Ni RS32580 Ni mycofactocin bifunctional cys sulfur carrier chorismate biosynthesis I glyceryl-L-cysteine tryptophan 2,3- phosphorylase: bifunctional cysteine desulfurase: a,c-diamide a [bis(guanylyl -N-acetylmuramyl- 23,24-bisnorchol- met met in tRNA Ile2 valyl-L-tyrosineradical SAM GTP cyclohydrolase protein ThiS phenylethanol biosynthesis dioxygenase: alanyl-[protein] L-valyl-[protein] a C-terminal uroporphyrinogen-III uroporphyrinogen-III BN1701_RS06475 adenosyltransferase: a [DNA]- 2,6-diamino-4- molybdopterin) BN1701_RS31990 (tetrapeptide) II: BN1701_RS00450 D-erythrose signal carbamoyl a 5'-phospho- an N-formyl- ala + a peptide with 4-en-22-oate maturase: mftC C-methyltransferase/ C-methyltransferase/ thioredoxin- cobO D-glyceraldehyde cysteine desulfurase: adenylyltransferase: his BN1701_RS08190 L-ornithine 4-oxo-2-pentenal a tetrahydrofolate phosphate H a proteinogenic [mycofactocin [+ 2 isozymes] phosphate nucleotide- [DNA] hydroxy-5-(N-methyl) L-methionyl- cofactor an N-terminal pyrophosphoryl- 2+ 2+ bifunctional disulfide 3-phosphate BN1701_RS06475 moeZ 4-phosphate peptidase Co Co precursor peptide]- uroporphyrinogen- uroporphyrinogen- 3-deoxy-7- phe histidine tryptophan 2,3- 3'-phosphate formamidopyrimidine met amino acid undecaprenol CorA cob(I)yrinic acid [initiator tRNA ] chaperone]-S- L-proline a [glutamine- Mg 2+ Mg 2+ III synthase: an S-sulfanyl-[L- 3,4-dihydroxy- reductase: [+ 2 isozymes] a carboxy- phosphoheptulonate II: lspA dioxygenase: mesaconate glutamine- glycyl-L-valyl- III synthase: a,c-diamide 1-deoxy-D-xylulose- ammonia- sulfanyl-L-cysteine ADP synthetase]- BN1701_RS24180 cysteine desulfurase] 2-butanone- trxB an [L-cysteine adenylated- synthase: aroF [+ 2 isozymes] BN1701_RS13865 hydrolyzing decarboxylated BN1701_RS24180 adenosyltransferase: 5-phosphate lyase: hutH N-Formyl-L- L-tyrosine 4-phosphate thioredoxin- desulfurase]-S- [ThiS sulfur- aromatic urocanate carbamoyl- L-tyrosine uroporphyrinogen-III uroporphyrinogen-III scaffold protein BN1701_RS19300 synthase: 3-deoxy-7- kynurenine 2+ 2+ mycofactocin synthase/GTP [corrinoid sulfanyl-L-cysteine carrier protein] an (S-diacyl-sn- a lipoprotein phosphate Co RS20600 Co C-methyltransferase: for iron-sulfur disulfide BN1701_RS04145 phosphoheptulonate amino 2+ 2+ C-methyltransferase: adenosyltranferase]- glyceryl)-L-cysteinyl- urocanate kynurenine a 7,8-dihydro- an N-formyl-L- a mature an N-terminal- 3-amino-5-[(4- Mg Mg radical SAM cobA cluster assembly: cyclohydrolase II: reductase: gly acid lyase: signal peptide synthase: sn-glycerol a CDP- a [protein]- a D-aspartyl- an L-asparaginyl- an L-cysteinyl- cobA cob(II)inamide 1-deoxy-D-xylulose- cysteine desulfurase: synthase class II: [apolipoprotein] hydratase: formamidase: 8-oxoguanine a (6S)-5- 3-sulfocatechol serotonin 5-MTR-1-P maturase: mftC BN1701_RS06225 (S)-citramalate diacylglycerol methionylaminoacyl- glu peptidoglycan L-glutamine asp Asn Cys L-methionyl- hydroxyphenyl) precorrin-1 BN1701_RS06480 trxB cmdF primary-amine carB carA 3-phosphate (n) [tRNA ] [tRNA ] [tRNA ] precorrin-1 5-phosphate BN1701_RS06475 3-deoxy- BN1701_RS03520 apolipoprotein N- BN1701_RS21635 BN1701_RS08195 in DNA formyltetrahydrofolate glycyl-[protein] methyl]-4,4- a C-terminal an S-sulfanyl-[cysteine 2,5-diamino-6- glycine oxidase: tRNA (meso-DAP S-methyl-5- [mycofactocin (5-phospho-D- synthase: [+ 2 isozymes] D-arabino- acyltransferase: lnt 4-imidazolone- carbamate containing) dimethyl-2- thioribose-1- Mg 2+ RS31315 Mg 2+ bifunctional bifunctional desulfurase]-[disordered- oxidase BN1701_RS13295 citramalate catechol 2,3- transglutaminase precursor peptide]- ribosylamino) a reduced [corrinoid BN1701_RS30960 heptulosonate 2-phenylethylamine apolipoprotein N- 5-propanoate L-kynurenine pyrrolidin-2-onemycofactocin phosphate uroporphyrinogen-III uroporphyrinogen-III form scaffold ThiO: thiO phenylacetaldehyde synthase: bifunctional DNA- CDP-diacylglycerol-- peptide bifunctional D-tyrosyl-tRNA(Tyr) peptidyl-tRNA peptidyl-tRNA type I methionyl glycyl-3-amino-5- pyrimidin- 1-deoxy-D- a thiocarboxylated- 7-phosphate acyltransferase: lnt a peptide dioxygenase: domain-containing C-methyltransferase/ C-methyltransferase/ protein] complex thioredoxin adenosyltranferase]- imidazolonepropionase: formamidopyrimidine glycerol-3-phosphate 3- deformylase: folylpolyglutamate endolytic deacylase: hydrolase: hydrolase: aminopeptidase: biosynthesis isomerase: xylulose 5- [ThiS sulfur- 3-dehydroquinate an N-acyl-(S-diacyl- kynureninase: BN1701_RS18110 BN1701_RS07550 protein: [(4-hydroxyphenyl) uroporphyrinogen- [cysteine desulfurase]-S- 4(3H)-one cob(I)inamide 2-iminoacetate 2-phenylethanol glycosylase/ phosphatidyltransferase: def synthase/ BN1701_RS03935 BN1701_RS33435 BN1701_RS33435 map FMN- mtnA uroporphyrinogen- carrier protein] sn-glyceryl)-L- BN1701_RS21620 transglycosylase BN1701_RS02920 S-methyl-5- Cd 2+ CadA Cd 2+ methyl]-4,4- sulfanylcysteine:[acceptor bifunctional phosphate synthase: dehydrogenase: BN1701_RS13860 pgsA catechol 2,3- dependent III synthase: III synthase: cob(I)yrinic acid cysteinyl-[lipoprotein] CO DNA-(apurinic peptide deformylase: dihydrofolate MltG: mltG [+ 2 isozymes] [+ 2 isozymes] [+ 2 isozymes] thio-D-ribulose dimethylpyrrolidin- protein]-cysteine diaminohydroxyphosphoribosylaminopyrimidine AIR BN1701_RS14345 kynureninase: pyruvate 2 dioxygenase: [+ 2 isozymes] BN1701_RS24180 BN1701_RS24180 a,c-diamide BN1701_RS05305 N-formimino- acetate or apyrimidinic BN1701_RS29090 synthase: [+ 2 isozymes] deaminase 1-phosphate 2-one sulfurtransferase: deaminase/5-amino-6-(5-phosphoribosylamino) thiazole synthase: kynU BN1701_RS07555 adenosyltransferase: L-glutamate site) lyase: mutM CMP 1-(3-sn- BN1701_RS02010 tRNA asp MftD: mftD uroporphyrinogen-III uroporphyrinogen-III BN1701_RS29060 3-dehydroquinate 6 D-aspartate PMFT BN1701_RS18335 uracil reductase RibD: ribD phosphomethylpyrimidine 2-phenylethanol a [protein] N - an N-terminal 2+ 2+ cobO glycine cleavage phosphatidyl) Asn Cys Cd CadA Cd C-methyltransferase: C-methyltransferase: a [cysteine desulfurase]- 5-amino-6-(5- synthase ThiC: thiC menaquinol-7 biosynthesis L-threonine anthranilate a mature GlcNAc-1,6- asn tRNA cys a tRNA met glycyl-[protein] 2-[(2R,5Z)- type II 3- -sn-glycerol formate a L-methionylaminoacyl- (2Z,4E)-2- [(5-hydroxy-1H- cobA cobA S-sulfanyl-[disordered- phospho-D- cob(I)yrinic acid periplasmic disulfide bond formation degradation III (to a [glycine-cleavage a [DNA]- a 5'-phospho- 7,8-dihydro- a (6S)-5- peptidoglycan anhMurNAc- sulfite 2-carboxy-4- dehydroquinate 4-oxo-2-pentenal 3-phosphate tRNA (n) hydroxyhexa- indol-3-yl)ethyl]- 3-amino-5-[(4- form scaffold a,c-diamide HMP-P all-trans- 6 nucleotide- γ D-ribulose ribosylamino)uracil methylglyoxal) complex H protein] N glycine cleavage system [DNA] 8-oxoguanine formyltetrahydrofolate (meso-DAP L-Ala- -D-Glu- 2,4-dienedioate L-glutamine hydroxyphenyl) precorrin-2 precorrin-2 protein] complex adenosyltransferase: methylthiazol-5(2H heptaprenyl 1,4-dihydroxy- dehydratase: aroQ a [DsbB protein] a [DsbA protein] two reduced 3'-phosphate 2+ 2+ 5-phosphate bifunctional an electron- glu -[(R)-lipoyl]-L-lysine aminomethyltransferase containing) DAP-D-Ala Co CbiQ Co methyl]-4,4- cysteine desulfurase: BN1701_RS19300 bifunctional )-ylidene]ethyl diphosphate 2-naphthoate with reduced L- carrying a cysteine residues thr precorrin-2 (C 20 )- diaminohydroxyphosphoribosylaminopyrimidine 3-dehydroshikimate transfer quinone precorrin-2 BN1701_RS06475 bifunctional hydroxymethylpyrimidine phosphate cysteine residues disulfide bond in a protein L-threonine 3- L-serine degradation GcvT: gcvT dimethyl-2- methyltransferase: deaminase/5-amino-6-(5-phosphoribosylamino) glycine cleavage system 5-deoxy-α- dehydrogenase: 3,4-dihydroxy- adenosylcobinamide kinase/ 1,4-dihydroxy- a purine base a pentaglycine cross- 7,8-dihydrofolate a peptidoglycan (1S,2R)-1- (S)-4-hydroxy- phosphoenol an N-terminal- a [2-oxoglutarate a peptide with pyrrolidin-2-one [+ 2 isozymes] shikimate dehydrogenase: aminomethyl- a protein with NADPH + 2-oxoglutarate isochorismate a nucleoside cobA cobJ an S-sulfanyl-[cysteine uracil reductase RibD: ribD aminomethyltransferase H dimer (E. faeciums) ser C-(indol-3- RNA L-methionyl-L- dehydrogenase an N-terminal D-ribose 1- a metal a metal mycofactocin 2-butanone- 5-amino-6-(5- phosphomethylpyrimidine 2-naphthoate dehydrogenase: tdh transferring lesion in DNA bridge of peptidoglycan LAXTG motif monoglutamate triphosphate 2-oxopentanoate dGDP pyruvate RS29860 L-2-amino-3- ser GcvT: gcvT 6 phosphate cation cation biosynthesis desulfurase]-S- 4-phosphate bifunctional kinase: thiD polyprenyltransferase: glycine yl)glycerol seryl-[protein] E2 protein] N L-alanine S-methyl-5- sirohydrochlorin precorrin-3A phospho-D- 2-(2-carboxy-4- BN1701_RS14370 oxobutanoate FMN- sulfanyl-[disordered- synthase/GTP adenosylcobinamide BN1701_RS24005 threonine/serine [+ 2 isozymes] dehydrogenase: D-alanyl-D-alanine 3-phosphate -dihydrolipoyl- thioribose-1- ribitylamino)uracil methylthiazol-5- Amine and Polyamine Biosynthesis bifunctional DNA- dihydrofolate 2-succinyl-5- 4-hydroxy-2- dihydrolipoyl dependent form scaffold cyclohydrolase II: kinase/ HMP-PP shikimate dehydratase: gcvP class E sortase: carboxypeptidase/ DNA-directed type I methionyl L-lysine phosphate protein] complex superpathway of tetrahydrofolate biosynthesis adenosylcobinamide- yl)ethyl phosphate BN1701_RS10660 a [glycine-cleavage formamidopyrimidine BN1701_RS26675 reductase: tryptophan enolpyruvyl- RNA polymerase: oxovalerate dehydrogenase: aminopeptidase a metal a metal deaminase [cysteine desulfurase]-S- BN1701_RS06225 a [glycine-cleavage D-alanyl-D-alanine- pyruvate aminopeptidase: isomerase: RS04465 demethylmenaquinol-7 6 glycosylase/ BN1701_RS32835 synthase 6-hydroxy-3- aldolase: dmpG lpdA N: pepN cation cation phosphate shikimate kinase: ectoine biosynthesis [+ 3 isozymes] 6 complex H protein] N - class E sortase: BN1701_RS23540 MftD: mftD sulfanylcysteine:[acceptor 1-deoxy-L- thiamine phosphate spermidine biosynthesis I 2-aminoprop- complex H protein] N DNA-(apurinic endopeptidase: dacB kinase: pyk map 5-deoxy-D-mtnA 5-[(4-hydroxyphenyl) cobalt- guanylyltransferase: BN1701_RS14350 aminomethyldihydrolipoyl- BN1701_RS32970 dihydrofolate subunit cyclohexene-1- BN1701_RS23545 [+ 2 isozymes] dihydrolipoyl precorrin-3B protein]-cysteine glycero-tetrulose ARP synthase: demethylmenaquinone aminoacetone 2-enoate -dihydrolipoyl-L-lysine [+ 2 isozymes] ribulose 1- methyl]-3-imino-4,4- sirohydrochlorin GTP BN1701_RS03265 L-lysine or apyrimidinic reductase: alpha: trpA carboxylic-acid dehydrogenase: sulfurtransferase: 4-phosphate BN1701_RS29045 methyltransferase: a peptidoglycan [+ 2 isozymes] a [2-oxoglutarate phosphate dimethylpyrrolidin- precorrin-3B C(17)- shikimate 3- asp primary-amine site) lyase: mutM a protein with LAXT BN1701_RS20535 [+ 2 isozymes] synthase: menD lpdA a metal a metal BN1701_RS18335 adenosyl-cobinamide BN1701_RS23890 SAM a peptide with an dehydrogenase ala a peptide RS01500 2-one a [cysteine pyridoxal 5'-phosphate biosynthesis I phosphate carboxyl end attached tetramer with a D-ala acetaldehyde pyruvate pyruvate an N-terminal cation cation methyltransferase: 6,7-dimethyl-8- GTP aspartate kinase: oxidase: dGTP E2 protein] N 6 phosphate thiamine N-terminal glycine D,D cross-link D-glyceraldehyde met cobJ desulfurase]-(S- ribityllumazine cyclohydrolase menaquinol-7 3-phosphoshikimate 1- BN1701_RS28025 BN1701_RS13295 a [DNA]- a 5'-phospho- a modified to a pentaglycine cross- 5,6,7,8- 2-succinyl-5-enolpyruvoyl- RNA L-seryl-[protein] -lipoyl-L-lysine L-cysteine degradation II + (Enterococcus sulfanyl) -[disordered- bifunctional phosphate D-erythrose carboxyvinyltransferase: adenosylmethionine DsbA family 2-iminopropanoate nucleotide- 4-oxo-2-pentenal bridge of peptidoglycan NADP 3-phosphate trp 6-hydroxy-3-cyclohexene- cobalt-factor III 2 synthase: I FolE: folE L-aspartyl- glycine cleavage system L-threonine [DNA] nucleobase tetrahydrofolate precorrin-4 4-phosphate aroA decarboxylase: speD oxidoreductase: methylglyoxal 3'-phosphate faecium) a metal a metal form scaffold BN1701_RS06230 7,8- adenosylcobinamide thiamine- 4-phosphate aminomethyltransferase degradation II 1-carboxylate RS19540 PMFT protein] complex dihydroneopterin kinase/ 5-enolpyruvoyl- BN1701_RS29165 cation cation precorrin-4 C(11)- phosphate kinase: putrescine dAdoMet a [DsbB protein] a [DsbA protein] cys GcvT: gcvT 3'-triphosphate adenosylcobinamide- shikimate 3- aspartate- an electron- an intra- methyltransferase: 6,7-dimethyl-8-(1- BN1701_RS17335 carrying a with reduced L- cystathionine 5-amino-5-(4- a carboxy- sn-glycero-3- a Xaa-Pro an N-terminal- a DNA containing a (1->4)- mycofactocin phosphate phosphate semialdehyde transfer quinol protein disulfide thr phosphoenol cobM D-ribityl)lumazine 4-phospho- disulfide bond cysteine residues gamma-lyase: hydroxybenzyl)- pyruvate a uracil in DNA L-methionyl-L- digallate γ-L-glutamyl- gly α-D-glucan biosynthesis thiamine chorismate dehydrogenase: pyruvate L-threonine 3- SAM adenylated- cys phospho-N- dipeptidyl- a mismatch dADP pyruvate ATP a metal a metal cobalt-precorrin-3 guanylyltransferase: spermidine synthase: BN1701_RS17395 6-(D-ribitylimino) cysteinyl-[protein] tannase/feruloyl D-alanine 1,4-alpha- RS01655 glycosyltransferase a [cysteine desulfurase]- riboflavin synthase: diphosphate D-erythronate synthase: BN1701_RS28030 L-glutamine 2-aminoprop- dehydrogenase: [ThiS sulfur- (arachidonoyl) peptidase biotin cation cation precorrin-5 7,8- BN1701_RS03265 BN1701_RS07115 L-glutamine -5,6-dihydrouracil esterase family alpha/ glucan MftF: mftF [scaffold protein- BN1701_RS06220 D-glyceraldehyde aroC degradation II 2-enoate L-alanine tdh carrier protein] ethanolamine substrate pyruvate L-aspartate 4- [+ 2 isozymes] degradation I L-2-amino-3- pyruvate, uracil-DNA G/U mismatch- branching (2Fe-2S)] complex dihydroneopterin adenosylcobinamide- 3-phosphate degradation IV type I methionyl beta hydrolase: glutathione semialdehyde N 6 -L-threonylcarbamoyladenosine 37 oxobutanoate phosphate dikinase: glycosylase: specific DNA protein MFT-1 riboflavin 3'-phosphate GDP chorismate BN1701_RS07285 biotin--[acetyl-CoA- synthase: a metal a metal chorismate (3R)-3-hydroxy-2-oxo- gln bifunctional FO BN1701_RS10475 cysteine desulfurase: glycerophosphodiester Xaa-Pro dipeptidyl- BN1701_RS30440 aminopeptidase: glycosylase: pyruvate diaminobutyrate- -modified tRNA biosynthesis gln glycine C- carboxylase] ligase: gshB GlgB: glgB RS13950 cobalt-precorrin-4 1-deoxy-D-xylulose- 4 phosphooxybutanoate spermidine glutamate synthase ala biosynthesis BN1701_RS18335 phosphodiesterase: peptidase: map mug kinase: pyk tannase/feruloyl a (1,6)-α-D- cation cation mycofactocin bifunctional aminodeoxychorismate/ adenosylcobalamin -2-oxoglutarate pyridoxal 5'- acetyltransferase: [+ 2 isozymes] uracil-DNA BN1701_RS22190 precorrin-6A a [co-chaperone]- 5-phosphate large subunit: gltB 2-iminopropanoate alanine protein CofGH: [+ 2 isozymes] BN1701_RS27055 BN1701_RS03835 [+ 2 isozymes] esterase family alpha/ glucosyl-(1,4) biosynthesis cobalt precorrin- riboflavin kinase/ anthranilate synthase salvage from cobalamin phosphoserine transaminase: ectB thr phosphate BN1701_RS26415 glycosylase: [scaffold protein- D-erythro-7,8- synthase: glutamate synthase dehydrogenase: ald BN1701_RS10915 [+ 2 isozymes] [+ 2 isozymes] beta hydrolase: -α-glucan glycosyltransferase 4 (C 11 )- FAD synthetase: component II: transaminase: threonylcarbamoyl- synthase: phosphoenol BN1701_RS17255 an apyrimidinic uracil norophthalmate a metal a metal (2Fe-2S)] complex BN1701_RS04145 diaminobutyrate- large subunit: gltB + BN1701_RS23335 biotinyl-5'- MftF: mftF BN1701_RS16450 dihydroneopterin BN1701_RS26720 mycothiol biosynthesis cob(I)alamin BN1701_RS29455 pdxT pdxS alanine gly diphosphate H a thiocarboxylated- an N-terminal L- pyruvate RS21905 methyltransferase: SSQ1 -2-oxoglutarate AMP synthase: glu AMP pyruvate site in DNA dATP cation cation 1-deoxy-D-xylulose- dehydrogenase: ald 7,8-didemethyl- ala [ThiS sulfur- a dipeptide with met cysteinyl-[protein] gallate adenylate cobA dihydroneopterin aminodeoxychorismate 4-phosphooxy- transaminase: ectB BN1701_RS19405 [+ 15 isozymes] 5'-deoxyadenosine AMP anandamide sn-glycerol uracil MFT-2 chaperone: FMN D-glucopyranose 5-phosphate pyruvate 8-hydroxy-5- met carrier protein] a C-terminal a peptide an apyrimidinic precorrin-6B aldolase: folB synthase L-threonine glu pyruvate 3-phosphate cobalt- dnaK 6-phosphate synthase: L-2,4- threonylcarbamoyl- L-glutamate deazariboflavin L-proline site in DNA a [chaperone-ATP]- bifunctional component I: pabB cob(II)alamin 2+ 2+ precorrin-5A 6-(hydroxymethyl) inositol-3-phosphate BN1701_RS30960 diaminobutanoate AMP synthase: degradation I Zn RS28715 Zn precorrin-6y C5,15- [co-chaperone]- riboflavin kinase/ -7,8-dihydropterin 4-amino-4- synthase: (L-threonylcarbamoyl)BN1701_RS32890 methyltransferase [scaffold protein- FAD synthetase: cob(I)yrinic acid a [ribosomal a 2'- 3-benzyl-3,6 - an N-terminal- a [lipoyl-carrier an unstable 2-amino-4-hydroxy-6- deoxychorismate BN1701_RS13815 1-deoxy-D- 3-amino-1- adenylate glu a [DNA]-3'- + a 5'-phospho- 3-phospho- ADP-α-D-glucose (decarboxylating) a,c-diamide a sulfurated NAD deoxyribonucleoside uroporphyrinogen-III 6 RecA filament- MMFT-2 (2Fe-2S)] complex BN1701_RS16450 hydroxymethyldihydropteridine hydroxyacetone protein S12] hydroxyl [DNA] D-glycerate [DNA] bis(cysteinylglycine) L-methionyl-L- a tRNA precursor glu ala protein]-N -[(R) a protein xylulose 5- GTP 2-phospho- 2+ 2+ cobalt- subunit CbiE: cbiE aminodeoxychorismate inositol-3-phosphate adenosyltransferase: tRNA (adenosine(37)-N6)- NAD-glutamate [sulfur carrier] L-aspartate 89 5'-triphosphate - 6-(hydroxymethyl) uroporphyrinogen-III threonyl-[protein] DNA complex Zn RS01470 Zn diphosphokinase: folK phosphate 1-phosphate -dihydrolipoyl]- zinc-dependent DNA mycofactocin precorrin-5B SSQ1 FAD lyase: BN1701_RS25200 synthase: cobO (2S)-4-acetamido- threonylcarbamoyltransferase dehydrogenase: -diketopiperazine C-methyltransferase: L-lactate precorrin-7 (7,8-dihydropterin- L-lysine dihydrolipoyl metalloprotease: repair biosynthesis chaperone BN1701_RS26215 2-aminobutanoate complex: tsaD tsaB tsaE BN1701_RS01765 ATP-dependent glucosyl-3- cobA cobalt-precorrin- cob(I)yrinic acid 6 bifunctional 3'- type I methionyl glutamate-- dehydrogenase: BN1701_RS28555 protein 6-yl)methyl 4-aminobenzoate thiamine diphosphate salvage II an N -L- 2-oxoglutarate 30S ribosomal DNA ligase: phosphoglycerate ribonuclease D: glycosyltransferase 5B (C(1))- ATPase: dnaK a,c-diamide ectoine synthase: 2-phospho-L-lactate lpdA precorrin-6y C5,15- diphosphate 37 Respiration protein S12 5' exonuclease/ membrane bifunctional aminopeptidase: cysteine ligase: zinc-dependent RecO: thiol CydC thiol MftF: mftF Ins(3)P UDP-N-acetyl- BN1701_RS33310 threonylcarbamoyladenine BN1701_RS04395 synthase: BN1701_RS04220 guanylyltransferase: methyltransferase: methyltransferase α adenosyltransferase: 4-amino-2-methyl-5- methylthiotransferase DNA polymerase: dipeptidase: uroporphyrinogen-III map BN1701_RS00160 dihydrolipoyl metalloprotease: recO a [chaperone- -D-glucosamine pyridoxine [+ 2 isozymes] in tRNA [+ 5 isozymes] BN1701_RS31145 a stabilized BN1701_RS11175 (decarboxylating) dihydropteroate BN1701_RS19300 pyrimidinemethanol BN1701_RS00315 BN1701_RS04230 C-methyltransferase/ cofC dehydrogenase: MMFT-3 an [2Fe-2S] ADP]-[disordered- NAD de novo biosynthesis 5'-phosphate Tetrapyrrole Biosynthesis 2-oxoisovalerate decarboxylation to isobutanoyl-CoA RimO: rimO [+ 2 isozymes] [+ 3 isozymes] BN1701_RS32195 RecA filament- cobalt- subunit CbiE: cbiE cluster protein synthase: folP cob(II)alamin- uroporphyrinogen- a [lipoyl-carrierlpdA form scaffold I (from aspartate) D-inositol-3-phosphate bifunctional ectoine α [+ 12 isozymes] a nucleoside 5'- a peptide DNA complex [corrinoid pyridoxal 5'- 2-O-( -D- a tRNA L-lactyl-2- 6 sulfite RS27660 sulfite mycofactocin precorrin-6A dihydropteroate glycosyltransferase: hydroxymethylpyrimidine an [apo BCAA 3-benzyl-3,6 - III synthase: protein]-N -[(R precorrin-8x protein] complex phosphate synthase: tetrapyrrole biosynthesis a [ribosomal [DNA] NMN ADP glucopyranosyl) an N-terminal L- monophosphate γ-L-glutamyl- biosynthesis synthase: folP mshA adenosyltranferase] dehydrogenase 5'-deoxyadenosine an unsulfurated AMP BN1701_RS24180 diphospho- )-lipoyl]-L-lysine cobalt-precorrin- non- asp kinase/ I (from glutamate) siroheme biosynthesis TCA cycle TCA cycle IV (2-oxoglutarate decarboxylase) met protein S12]-3- -3-phospho- bis(cysteinyl)- 6- gly met threonyl-[protein] D-alanine glycosyltransferase BN1701_RS17475 6 [sulfur carrier] 5'-guanosine 6A reductase: precorrin-8X chaperonin phosphomethylpyrimidine E2 protein] N alpha-ketoacid methylsulfanyl- [DNA] (hydroxymethyl) precorrin-2 MftF: mftF 1-O-(2-acetamido- pyridoxamine D-glycerate acetate acetate BN1701_RS11170 methylmutase: molecular L-aspartate oxidase: 7,8- kinase: thiD -lipoyl-L-lysine dehydrogenase L-aspartate 89 -diketopiperazine 2-deoxy-α-D- 5'-phosphate glu uroporphyrinogen-III oxaloacetate RS27025 cobalt- BN1701_RS11145 chaperone BN1701_RS17965 dihydropteroate cob(I)alamin- dihydrolipoyl subunit beta: MMFT-4 2-iminosuccinate glucopyranosyl)-1D-myo oxidase: pdxH glutamate-- bifunctional a metal a metal precorrin-6B ATPase: dnaK bifunctional [corrinoid HMP-P dehydrogenase: BN1701_RS26005 hydrogenobyrinate -inositol 3-phosphate tRNA ligase: uroporphyrinogen-III a 2'- androsta-1,4- a mycothiol a [protein]-L- cation cation mycofactocin folylpolyglutamate adenosyltranferase] lpdA a ferrocytochrome stearoyl-CoA NADPH NAD + an N-modified γ cobalt-precorrin- an [Fe-S cluster quinolinate PLP bifunctional 5-(2-hydroxyethyl) BN1701_RS18085 C-methyltransferase/ cob(II)inamide 2-methylbutanoate deoxyribonucleoside diene-3,17-dione -L-glutamyl-(S)- gly S-conjugate his repressor LexA synthase/ cob(I)yrinic acid an L-glutamyl- dihydrolipoyl ATP b [DNA] aminoacyl-[tRNA] dITP methionine biosynthesis 15 biosynthesis oleate β-oxidation Fatty Acid and Lipid Degradation 5 2-aminobutanoate 6B (C )- hydrogenobyrinate synthase hydroxymethylpyrimidine -4-methylthiazole Glu uroporphyrinogen- 5'-triphosphate 3-ketosteroid-9- L-histidine N(alpha) transcriptional peptide- glycosyltransferase dihydrofolate a,c-diamide [tRNA ] dehydrogenase: testosterone degradation (anaerobic) RdgB/HAM1 family non- methyltransferase a,c-diamide synthase: chaperone]-ATP NadA: nadA kinase/ III synthase: alpha-hydroxylase -methyltransferase: repressor methionine synthase: adenosyltransferase: citrate synthase: lpdA an [apo BCAA mycothiol MftF: mftF [decarboxylating]: BN1701_RS11200 1-(2-acetamido- glutamyl-tRNA BN1701_RS24180 an [apo BCAA dehydrogenase acetate--CoA NAD(P)(+) subunit A: canonical purine NTP (S)-S-oxide cobO phosphomethylpyrimidine BN1701_RS29535 dehydrogenase oleate cob(I)yrinic acid a,c-diamide acyl-CoA bifunctional 3'- peptidyl-tRNA glutathione BN1701_RS26860 LexA: lexA quinolinate BN1701_RS02010 2-deoxy-α-D- 6 ligase: acs transhydrogenase pyrophosphatase: rdgB conjugate BN1701_RS11185 kinase: thiD reductase: 6 E2 protein] N -S-[2- testosterone BN1701_RS13065 reductase MMFT-5 hydrogenobyrinate 4-methyl-5-(2- uroporphyrinogen-III E2 protein] N adenosyltransferase: desaturase: 5' exonuclease/ hydrolase: synthase: amidase L-histidine N(alpha) transcriptional 7,8-dihydrofolate glucopyranosyl)- cob(I)yrinic acid adeninyl adenosylcobamide biosynthesis BN1701_RS24190 malate dehydrogenase: methylpropanoyl]dihydrolipoyl- long-chain fatty acetate--CoA (Re/Si-specific): nucleotide MsrA: msrA a,c-diamide carboxylating phosphooxyethyl) C-methyltransferase: -dihydrolipoyl- BN1701_RS19300 BN1701_RS00375 DNA polymerase: BN1701_RS33435 3-ketosteroid-9- gshB -methyltransferase: repressor a protein-L- cobalt-precorrin-7 monoglutamate 1D-myo-inositol a,c-diamide HMP-PP BN1701_RS22730 3-oxosteroid 1- ligase: acs BN1701_RS03030 Mca: mca mycofactocin from adenosylcobinamide-GDP (S)-4-amino-5- cobA (S)-malate citrate L-lysine L-lysine acid--CoA ligase: BN1701_RS00315 alpha-hydroxylase pyrophosphohydrolase: LexA: lexA cobaltochelatase nicotinate-nucleotide N-acetyl-1-D-myo- adenosyltransferase: thiazole dehydrogenase: cob(I)yrinic acid a,c-diamide [+ 6 isozymes] BN1701_RS03035 [+ 2 isozymes] egtD methionine- biosynthesis oxopentanoate precorrin-1 BN1701_RS29690 [+ 11 isozymes] subunit A: BN1701_RS27280 cleaved bifunctional cobalt- subunit CobN: cobN diphosphorylase: inositol-2-amino- BN1701_RS19300 BN1701_RS21355 adenosyltransferase: cobO BN1701_RS03040 hercynine (S)-S-oxide glycosyltransferase BN1701_RS17960 thiamine phosphate glutamate-1- [+ 10 isozymes] (2S)-2- BN1701_RS21360 ophthalmate dIMP repressor LexA precorrin-7 (C(5))- coenzyme A biosynthesis 2-deoxy-alpha- D- adenosylcob(III) adenine diphosphate α GlcN-Ins a mercapturate MftF: mftF cob(II)yrinate semialdehyde bifunctional 1-dehydrotestosterone methylbutanoyl-CoA a ferricytochrome an N-modified an uncharged 9 -hydroxyandrosta- methyltransferase/ I (prokaryotic) alamin-[corrinoid synthase: oleoyl-CoA adenosylcobinamide AMP oleoyl-CoA a,c-diamide NaMN a 7,8-dihydrofolate glucopyranoside uroporphyrinogen-III 2-oxo acid b amino acid tRNA 1,4-diene-3,17-dione cobalt-precorrin- BN1701_RS29045 2,1- triphosphate 5 [DNA] + MMFT-6 deacetylase: mshB adenosyltranferase] nicotinate-nucleotide-- fumarate hydratase: dehydrogenase NADH NADP 6B (C(15))- (R)-4'- aminomutase: C-methyltransferase/ aconitate hydratase: acyl-CoA/acyl-ACP nicotinate-nucleotide dihydrofolate cob(I)yrinic acid dimethylbenzimidazole BN1701_RS03925 subunit E2: mycofactocin methyltransferase: phosphopantothenate GlcN-Ins hemL uroporphyrinogen- BN1701_RS05710 dehydrogenase: bifunctional adenylyltransferase: reductase: a,c-diamide phosphoribosyltransferase: thiamine BN1701_RS26010 biosynthesis BN1701_RS11185 phosphopantothenoylcysteine phosphate III synthase: class II fumarate hydratase: BN1701_RS32540 BN1701_RS02390 BN1701_RS20535 adenosyltransferase: cobT 5-aminolevulinate ∆ 1 -dihydrotestosterone an NDP-α- a [protein]- an insertion a protein-L- cysteine--1-D-myo- BN1701_RS24180 BN1701_RS30785 3-phospho- a [protein]-L-lysine + glycosyltransferase decarboxylase/ cobO thiamine- [+ 14 isozymes] cob(II)alamin ala a pimeloyl-[acp] DL-allothreonine D-glucose FMN NADH H H O sequence cys L-homocysteine Ins(1)P methionine- nicotinate adenine dihydrofolate fumarate cis-aconitate ATP D-glycerate L-glutamine 2 GTP XTP dGDP MftF: mftF cobalt-precorrin-8 phosphopantothenate-- inosityl 2-amino- adenine ribotide uroporphyrinogen-III (R)-S-oxide dinucleotide reductase: cob(I)yrinic acid phosphate kinase: porphobilinogen (2E,9Z)- element IS30DDE-type integrase/ inositol peptide- cysteine ligase CoaBC: coaBC 2-deoxy-alpha-D- adenosylcobinamide- phosphate C-methyltransferase: 3-oxosteroid 1- RdgB/HAM1 family non- ribonucleoside- (R)-4'- NAD+ synthase: NAD+ synthase: BN1701_RS32835 a,c-diamide BN1701_RS17335 synthase: hemB succinate dehydrogenase/ aconitate hydratase: octadecenoyl-CoA monophosphatase: MMFT-7 glucopyranoside GDP cobA dehydrogenase: glucosyl-3- transglutaminase NADPH- transposase/ canonical purine NTP diphosphate methionine phosphopantothenoyl- BN1701_RS01670 BN1701_RS01670 adenosyltransferase: fumarate reductase BN1701_RS05710 enoyl-CoA cob(I)yrinic acid a,c-diamide 8-amino-7- serine cystathionine BN1701_RS04050 ligase: thiamine 1,17- BN1701_RS21355 phosphoglycerate domain-containing dependent FMN GTPase recombinase: pyrophosphatase: rdgB reductase: (R)-S-oxide mycofactocin L-cysteine a tetrahydrofolate BN1701_RS19300 porphobilinogen iron-sulfur subunit: hydratase: oxononanoate hydroxymethyltransferase: beta-synthase: NAD+ synthase: NAD+ synthase: BN1701_RS11265 diphosphate precorrin-2 dihydroxyandrostan- adenosyltransferase: cobO synthase: protein: reductase: ssuE ObgE: obgE BN1701_RS33440 inositol BN1701_RS13560 reductase biosynthesis cobyrinate bifunctional adenosylcobinamide- BN1701_RS03660 BN1701_RS23745 synthase: BN1701_RS15490 nucleotide BN1701_RS30575 BN1701_RS31905 BN1701_RS31905 3-one androsta-1- cob(I)yrinic acid a,c-diamide BN1701_RS31145 BN1701_RS02920 [+ 5 isozymes] an insertion[+ 17 isozymes] monophosphatase: BN1701_RS13565 MsrB: msrB glycosyltransferase phosphopantothenoylcysteine adenosylcobalamin GDP hydroxymethylbilane precorrin-2 flavin reductase: pyrophosphohydrolase: a [protein]-L- folate transformations III (E. coli) deacetylmycothiol succinate dehydrogenase (S)-3-hydroxy-(9Z) adenosyltransferase: BN1701_RS16670 [+ 2 isozymes] sequence IS30 BN1701_RS23905 + ribazoletransferase: synthase: hemC dehydrogenase: ene-3,17-dione [+ 2 isozymes] BN1701_RS13130 BN1701_RS27280 GDP methionine MftF: mftF decarboxylase/ NAD hydrophobic membrane -octadecenoyl-CoA BN1701_RS19300 α + with integrated myo-inositol phosphopantothenate-- mycothiol cobS cobA 2-O-( -D- phosphate H XMP preuroporphyrinogen anchor subunit: 3-hydroxyacyl-CoA (8S)-8-amino-7- a nucleoside GDP transposon L-cystathionine MMFT-8 cysteine ligase CoaBC: coaBC a tetrahydrofolate synthase: NAD salvage pathway I (PNC VI cycle) glucopyranosyl) a protein with an α α BN1701_RS22595 succinate D-threo-isocitrate dehydrogenase: 17-hydroxyandrostan- acetaldehyde diphosphate + cob(II)yrinate Co -[ -(adenin-9-yl)]- sirohydrochlorin adenosylcobalamin oxononanoate acyl-carrier protein gly 6 FMNH NAD mshD -3-phospho- N -(γ-glutamyl)- 2 mycofactocin a,c-diamide Coβ-adenosylcobamide bifunctional NADP-dependent BN1701_RS04665 1,3-dione triphosphate 4'-phosphopantetheine methionine + fatty acid β-oxidation I (generic) D-glycerate L-lysine crosslink biosynthesis dihydrofolate reductase: 5'-phosphate NAD uroporphyrinogen-III sirohydrochlorin 3-oxo-(9Z)- synthase: metH mycothiol succinate-semialdehyde isocitrate dehydrogenase: glycosyltransferase pantetheine- BN1701_RS20535 Coα-[a-(aden- C-methyltransferase/ chelatase: BN1701_RS22670 octadecenoyl-CoA methionine synthase: NAD+ synthase: dehydrogenase (NADP(+) a (3Z)-alk-3- MftF: mftF phosphate dihydrofolate reductase: 9-yl)]-Coβ- NAD(+) uroporphyrinogen- BN1701_RS02595 acetyl-CoA C- UDP-N-acetyl-α-D-muramoyl- N-acetyl-muramoyl-(L- an sn-glycero-3- (1E,4S,5E,7R)- (1E,4S,5E,7R)- (3R,5S)-3- BN1701_RS18250 BN1701_RS01670 ): BN1701_RS15845 androstan- enoyl-CoA di-trans,octa-cis- quinoxaline-2- a D-tyrosyl- O-phospho- benzimidazolyl adenosylcobamide adenylyltransferase: BN1701_RS32835 adenosylcobamide diphosphatase: nudC III synthase: sirohydrochlorin γ alanyl-γ-D-glutamyl-L- phospho-N-(acyl) oxaloacetate urea-1-carboxylate germacra-1(10) germacra-1(10) cys Ins(2)P RNA NAD+ synthase: acyltransferase: L-alanyl- -D-glutamyl-L- aryl-carrier protein carboxyl adenylate Tyr hydroxy-1- MMFT-9 serine NAD+ synthase: 1,3,17-trione undecaprenyl phosphate ITP [tRNA ] L-homoserine biosynthesis from adenosylcobinamide-GDP coaD 5-methylbenzimidazolyl adenosylcobamide 5'-phosphate BN1701_RS01670 NAD(+) BN1701_RS24180 chelatase: BN1701_RS03895 lysyl-D-alanyl-D-alanine lysyl-D-alanyl-D-alanine) ethanolamine ,5-dien-11-ol ,5-dien-11-ol pyrroline-5- hydroxymethyltransferase: BN1701_RS31905 inositol 3'-dephospho- biosynthesis from adenosylcobinamide-GDP a 7,8-dihydrofolate a 5-methyltetrahydrofolate phosphatase: diphosphatase: nudC uroporphyrinogen- BN1701_RS31585 carboxylatepyrroline-5- BN1701_RS15490 NAD+ synthase: (7Z)-hexadecenoyl-CoA allophanate monophosphatase: benzimidazole CoA glycine cleavage system BN1701_RS34940 III synthase: a (2E)-2- phospho-N- D-tyrosyl-tRNA(Tyr) cystathionine ribonuclease carboxylate BN1701_RS31905 siroheme succinate semialdehyde 2-oxoglutarate acyl carrier protein: D-alanyl-D-alanine glycerophosphodiester hydrolase subunit 1: geosmin synthase: geosmin synthase: BN1701_RS04050 dephospho- 5-methylbenzimidazole [+ 2 isozymes] aminomethyltransferase Coα-[α-(adenin-7-yl)]- nicotinate adenine dinucleotide NMN BN1701_RS31580 enoyl-CoA enoyl-CoA acetylmuramoyl- BN1701_RS33295 carboxypeptidase/ phosphodiesterase: phosphoenolpyruvate deacylase: gamma-synthase: PH: rph reductase: nicotinate-nucleotide-- acyl-CoA/acyl-ACP BN1701_RS25190 BN1701_RS05110 BN1701_RS05110 inositol CoA kinase: GcvT: gcvT a (6S)-5-formyltetrahydrofolate Coβ-adenosylcobamide hydratase: pentapeptide- [+ 8 isozymes] D-alanyl-D-alanine- BN1701_RS09980 carboxykinase (GTP) BN1701_RS03935 BN1701_RS30585 proC mycothiol dimethylbenzimidazole nicotinate-nucleotide-- uroporphyrinogen-III dehydrogenase: a 2,3,4-saturated acyl-CoA/acyl-ACP monophosphatase: BN1701_RS05535 acyl-CoA BN1701_RS23745 transferase: endopeptidase: dacB : BN1701_RS26105 allophanate Hyp oxidation phosphoribosyltransferase: dimethylbenzimidazole 5-formyltetrahydrofolate BN1701_RS32540 dehydrogenase: a 2,3,4- [+ 2 isozymes] BN1701_RS23905 nicotinate-nucleotide fatty acid synthetase: BN1701_RS16015 hydrolase: atzF a nucleoside RNA [+ 14 isozymes] a quinoxaline-2- (8S,9S,10S)-8,10- myo-inositol cobT coenzyme A phosphoribosyltransferase: methylenetetrahydrofolatecyclo-ligase: adenylyltransferase: BN1701_RS00320BN1701_RS00065 saturated (3R)-3- acetone acetone (-)-geosmin diphosphate methylenetetrahydrofolate Pentose Phosphate Pathways superpathway of glycolysis and the Entner-Doudoroff pathway Tyr dimethyl-1-octalin mycothiol benzimidazole cobT dehydrogenase: BN1701_RS29960 (2E,7Z)- [+ 14 isozymes] a 2,3,4- hydroxyacyl-CoA carboxyl-[aryl- N-acetyl-muramoyl-(L- D-tyrosine a tRNA L-cystathionine reductase: BN1701_RS03565 BN1701_RS02390 multifunctional oxoglutarate [+ 10 isozymes] a 2,3,4-saturated AMP sn-glycerol an N- phosphoenolpyruvate adenosylcobinamide- ribotide BN1701_RS22750 phosphopantothenate biosynthesis I hexadecenoyl-CoA saturated (3S)-3- undecaprenyl-diphospho-N- UMP carrier protein] alanyl-γ-D-glutamyl- D-ala IDP ammonium CO 5-methylbenzimidazole decarboxylase/oxoglutarate D-glucopyranose 3-phosphate acylethanolamine 2 GDP adenosylcobinamide- a 5,10-methylenetetrahydrofolate a 5,10-methenyltetrahydrofolate pentose phosphate pathway fatty acyl CoA hydroxyacyl-CoA acetylmuramoyl-L-alanyl-γ-D- L-lysyl-D-alanine) phosphate ribotide phosphate dehydrogenase thiamine enoyl-CoA mycothione GDP 6-phosphate glutamyl-L-lysyl- D-alanyl-D-alanine 3-methyl-2-oxobutanoate NaMN nicotinamide pyrophosphate-binding hydratase: reductase: adenosylcobinamide- biotin biosynthesis from bifunctional D-glucopyranose subunit/dihydrolipoyllysine- BN1701_RS23745 BN1701_RS16705 adenosylcobinamide- methylenetetrahydrofolate 3-methyl-2-oxobutanoate 6-phosphate coenzyme A γ GDP 8-amino-7-oxononanoate I UDP-N-acetyl-α-D- 7,8-didemethyl- 3-(D-glyceryl) trans,octacis L-alanyl- -D- DNA containing a peptide with β-D-glucose hydrogen a reduced GDP dehydrogenase/ residue succinyltransferase (S)-3-hydroxy-(7Z) di-trans,octa-cis- pyridoxamine A(H2) N-ethylglycine ribazoletransferase: hydroxymethyltransferase: glucose-6- glucose-6- muramoyl-L-alanyl-γ-D- 8-hydroxy-5- -diphospho- -decaprenyl glycerophosphoserine glutamyl-L-lysyl- an N-terminal 6-phosphate (8S)-8-amino-7- 2-methyladeninyl adenosylcobamide methenyltetrahydrofolate subunit: BN1701_RS21585 -hexadecenoyl-CoA a 2,3,4-saturated a 2,3,4-saturated undecaprenyl phosphate PRPP a base with lesion 5'-phosphate ITP peroxide factor 420 cobS ribazoletransferase: panB phosphate phosphate acetyl-CoA C- glutamyl-L-lysyl-D-alanine deazariboflavin 5'-guanosine phosphate D-alanyl-D-alanine L-proline pyridoxal 5'- inositol-3-phosphate NADPH- oxononanoate biosynthesis from adenosylcobinamide-GDP cyclohydrolase: nicotinate 3-hydroxyacyl-CoA fatty acyl CoA 3-oxoacyl-CoA mycothione adenosylmethionine- cobS dehydrogenase: dehydrogenase: acyltransferase: phosphate synthase: synthase: RdgB/HAM1 family non- dependent Coα-[α- -8-amino-7- BN1701_RS22750 2-dehydropantoate phosphoribosyltransferase: zwf dehydrogenase: glycerophosphodiester G/U mismatch- BN1701_RS13815 canonical purine NTP catalase/ glycine α α zwf BN1701_RS03895 phospho-N- 2-phospho-L- decaprenyl-phosphate D-alanyl-D-alanine BN1701_RS17475 F420 (benzimidazolyl)]-Co Co -[ -(5- 2-methyladenine BN1701_RS33480 BN1701_RS04665 phosphodiesterase: specific DNA prolyl pyrophosphatase: rdgB peroxidase oxidase oxononanoate 10 glucose-6-phosphate inositol-3-phosphate reductase: β methylbenzimidazolyl)]- an N -formyltetrahydrofolate glucose-6-phosphate acetylmuramoyl- lactate transferase: phosphoribosyltransferase: carboxypeptidase/ pyridoxamine HPI: katG ThiO: thiO -adenosylcobamide transaminase: nicotinate glucose-6-phosphate 3-oxo-(7Z)- BN1701_RS09980 glycosylase: aminopeptidase: pip synthase: nucleotide npdG Coβ-adenosylcobamide nicotinate-nucleotide-- dehydrogenase: dehydrogenase: pentapeptide- BN1701_RS21955 BN1701_RS27505 D-alanyl-D-alanine- 5'-phosphate 5'-phosphate BN1701_RS18060 isomerase: hexadecenoyl-CoA [+ 2 isozymes] mug BN1701_RS26215 pyrophosphohydrolase: an oxidized 5'-phosphate dimethylbenzimidazole molybdenum BN1701_RS06345 BN1701_RS06345 transferase: endopeptidase: dacB oxidase: pdxH adenosylcobamide (7R,8S)-diaminononanoate phosphoribosyltransferase: β-alanine 6-phospho BN1701_RS06350 acetyl-CoA C- BN1701_RS27280 factor 420 adenosylcobamide cofactor biosynthesis (R)-pantoate BN1701_RS16015 trans,octacis- PLP Ins(3)P A H O ethylamine glyoxylate phosphatase: molybdopterin biosynthesis acyltransferase: oxidized 3PG- a DNA containing 2 phosphatase: cobT D-glucono- acetyl-CoA L-alanyl-γ-D- a modified a peptide pro IMP BN1701_RS34940 ATP-dependent BN1701_RS03895 factor 420-0 GMP decaprenylphospho- sn-glycerol an apurinic/ α α BN1701_RS34940 1,5-lactone β ser nucleobase Co -[ - dethiobiotin molybdate pantoate--beta-alanine 6-phospho undecaprenyl-diphospho-N UMP -D-ribofuranose 3-phosphate glutamyl-L- D-ala apyrimidinic site Coα-[α-(5- 6-phosphogluconolactonase: γ (benzimidazolyl)]-Co synthetase 2-methyladenine ribotide phosphate ligase: BN1701_RS28615 D-glucono- (5Z)-tetradecenoyl-CoA Detoxification -acetylmuramoyl-L-alanyl- - 5-phosphate lysyl-D-alanine β methylbenzimidazolyl)]- predicted GTP -adenosylcobamide BioD: bioD adenosylcobinamide-GDP molybdopterin pgl 1,5-lactone D-glutamyl-L-lysyl- D-alanine Coβ-adenosylcobamide ABC cys ATP D-gluconate 6-phosphogluconolactonase: acyl-CoA/acyl-ACP transporter (R)-pantothenate GTP 3',8- reactive oxygen species degradation dethiobiotin dehydrogenase: phenylmercury 6 cysteine desulfurase: 6-phosphate pgl arsenate N -(3-methylbut- 7,8-didemethyl- enolpyruvoyl- a 1-acyl-2- N-acetyl-D- an N-hydroxy- adenosylcobinamide-GDP of molybdate: cyclase BN1701_RS00065 isobutanal pimeloyl-CoA a RNA-DNA hybrid a kanamycin a 28S rRNA an unfolded type III pantothenate decarboxylating 6- acetate degradation detoxification a sulfurated [sulfur carrier] 2-en-1-yl)- 8-hydroxy-5- 2-diphospho- ala arachidonoyl- galactosamine arylamine sarcosine biotin synthase ribazoletransferase: cobS modA modB BN1701_RS06475 MoaA: moaA D-gluconate superoxide dADP protein bis(guanylyl molybdopterin) NAD salvage molybdopterin kinase: BN1701_RS36105 F6P [+ 14 isozymes] II (glutaredoxin) adenosine 37 in tRNA deazariboflavin 5'-guanosine sn-glycerol 6-phosphate aminoglycoside arylamine N- RICIN domain- BioB: bioB [+ 2 isozymes] (8S)-3',8-cyclo-7,8- phosphogluconate 6-phosphate mercuriphenyl chaperonin cofactor sulfurylation pathway III (to thiamine diphosphate adenine an [L-cysteine a carboxy-adenylated dehydrogenase: gnd (2E,5Z)- 3-phosphate CTP phosphotransferase: acetyltransferase: containing protein: ribonucleoside- molybdate type I pantothenate dihydroguanosine phosphogluconate superoxide acetate arsenate GroEL: groL Coα-[α-(2-methyladenin-9-yl)]-Co dinucleotide class II fructose- tetradecenoyl-CoA acetaldehyde bifunctional RNase BN1701_RS18490 9-mercaptodethiobiotin nicotinamide riboside) biosynthesis III kinase: BN1701_RS27235 desulfurase]-S- [small subunit of 5'-triphosphate D-ribulose 6-phosphofructokinase: dismutase: arsenate reductase: 2-phospho-L- 8-amino-7- N-acetylglucosamine- BN1701_RS10000 BN1701_RS33415 diphosphate chaperonin β-adenosylcobamide 5'-phosphate dehydratase: bisphosphatase: tRNA (N6-isopentenyl dehydrogenase H/acid phosphatase: glycine oxidase cys + (Staphylococcus) sulfanyl-L-cysteine molybdopterin synthase] cyclic pyranopterin 5-phosphate organomercury lactate transferase: 6-phosphate aminoglycoside arylamine N- RICIN domain- reductase: NADP BN1701_RS11050 BN1701_RS03500 ∆ 3 2 BN1701_RS15375 BN1701_RS31445 adenosine(37)-C2)- oxononanoate phosphatidate GroEL: groL 2-(2-carboxy-4- α molybdopterin (R)-4'-phosphopantothenate glpX -cis-∆ -trans-enoyl- enoyl-CoA (acetylating): BN1701_RS34940 phosphotransferase: ThiO: thiO biotin synthase Co -[a-(2-methyladen-9-yl) monophosphate [+ 2 isozymes] lyase: methylthiotransferase BN1701_RS21955 synthase: cytidylyltransferase: deacetylase: nagA acetyltransferase: containing protein: BN1701_RS13560 cysteine desulfurase: methylthiazol-5- β molybdotransferase β class II fructose- CoA isomerase: hydratase: arsenate BN1701_RS07600 [+ 2 isozymes] BN1701_RS19685 a protein BioB: bioB HMP-PP ]-Co -adenosylcobamide 5'- synthase ribulose- ribose-5-phosphate KDGP -D-fructose 1,6- BN1701_RS01360 MiaB: miaB BN1701_RS16670 BN1701_RS16835 BN1701_RS23975 BN1701_RS26275 BN1701_RS13565 yl)ethyl phosphate bisphosphate BN1701_RS04665 BN1701_RS23745 hydrogen reductase ArsC: a kanamycin an N- BN1701_RS06475 phosphate phosphatase: di-trans,poly-cis MoeA: MoaC: moaC phosphate 3- isomerase: bisphosphate [+ 2 isozymes] a 28S rRNA ADP NAD + aldolase: peroxide BN1701_RS00750 dehydro D-galactosamine [+ 2 isozymes] biotin BN1701_RS34940 -undecaprenyl BN1701_RS29125 a thiocarboxylated 3'-phosphate acetoxyarylamine glyoxylate methylamine fragments epimerase: BN1701_RS01880 6 a CDP-1-acyl- a nucleoside 5'- acetate an [L-cysteine thiamine phosphate [small subunit of cyclic pyranopterin BN1701_RS11080 (3E,5Z)-tetradeca- (S)-3-hydroxy-(5Z) acetate benzene Hg 2+ arsenite N -(3-methylbut-2-en- factor 420-0 GMP (8S)-8-amino-7- DNA 6-phosphate NAD(+) Coα-[α-(2-methyladenin-7- phosphate biosynthesis molybdopterin rpe bifunctional 5'-deoxyadenosine an unsulfurated coenzyme A 2-arachidonoyl- monophosphate desulfurase]-S- synthase: S-adenosyl-L- molybdopterin synthase] phosphate class II fructose- 3,5-dienoyl-CoA -tetradecenoyl-CoA catalase/ 1-yl)-2-(methylsulfanyl) met isobutanoyl-CoA NADH H + oxononanoate diphosphatase: yl)]-Coβ-adenosylcobamide (2E,6E)-farnesyl molybdotransferase D-ribose 5- 4-hydroxy-2- mercury(II) 37 [sulfur carrier] glycerol sulfanyl-L-cysteine BN1701_RS29045 IPP methionine salvage II bisphosphate DHAP peroxidase adenosine in tRNA bis(guanylyl nudC diphosphate MoeA: D-xylulose phosphate oxoglutarate acyl-CoA 3-hydroxyacyl-CoA reductase: cysteine desulfurase: molybdopterin aldolase: fbaA dehydrogenase: HPI: katG molybdopterin) BN1701_RS29970 5-phosphate aldolase/2- thioesterase: H O hydroxyl radical merA BN1701_RS06475 NAD(+) thiamine synthase: 2 cofactor SAH dehydro-3-deoxy- BN1701_RS01770 BN1701_RS04665 arsenite a nascent peptidoglycan 7,8-didemethyl- L-lactyl-2- Nα,Nε-diacetyl-lysyl- 3-amino-4- D-sedoheptulose a glucosylated diphosphatase: isoprenyl triose-phosphate + [+ 2 isozymes] phosphate MoO - BN1701_RS29255 0 NADP FMNH O-ureido-L- a DNA segment an arylamine 2 adenosylhomocysteinase: transketolase: phosphogluconate [+ 4 isozymes] 3-oxo-(5Z)- O Hg (meso-DAP containing) 8-hydroxy-5- diphospho- D-alanyl-D-alanine 2 a type IV prepilin asp hydroxybenzoate 1-phosphate a protein glycogenin a [bis(guanylyl transferase: menaquinol-10 biosynthesis isomerase: 2 ATP nudC molybdopterin deazariboflavin 5'-guanosine a tRNA precursor homoserine DDE-type integrase/ arylamine N- 1,4-alpha- BN1701_RS02730 BN1701_RS21880 BN1701_RS17880 aldolase: eda BN1701_RS06305 (3E,5Z)- tetradecenoyl-CoA arylamine N- ATP-dependent molybdopterin) cofactor CTP glucan NMN molybdopterin all-trans- [+ 2 isozymes] transposase/ acetyltransferase: acetyltransferase: cofactor [bis-MGD cofactor isoprenyl L-homocysteine tetradecadienoate acetyl-CoA C- endolytic D-alanyl-D-alanine NADPH- class II fructose- Clp protease: branching decaprenyl 1,4-dihydroxy- D-glyceraldehyde 2-phospho-L- argininosuccinate recombinase: BN1701_RS23975 BN1701_RS10000 chaperone]-S- chaperone]- transferase: acyltransferase: transglycosylase carboxypeptidase/ dependent FMN prepilin peptidase: bisphosphate BN1701_RS01940 protein bifunctional thiamine methionine synthase: metH diphosphate 2-naphthoate D-sedoheptulose D-glyceraldehyde lactate transferase: CCA tRNA synthase: BN1701_RS33440 arylamine N- arylamine N- sulfanyl-L-cysteine bis-MGD BN1701_RS30710 3-phosphate BN1701_RS03895 MltG: mltG D-alanyl-D-alanine- reductase: ssuE BN1701_RS00105 aldolase: fbaA BN1701_RS01945 metallophosphatase/ nucleotidyltransferase: [+ 3 isozymes] acetyltransferase: GlgB: glgB methionine synthase: 7-phosphate 3-phosphate type I (3Z)-dodec- [+ 2 isozymes] BN1701_RS21955 endopeptidase: dacB [+ 2 isozymes] BN1701_RS14100 a DNA segment acetyltransferase: clpX dipyrromethane 5'-nucleotidase: thiamine 1,4-dihydroxy- BN1701_RS26470 flavin reductase: BN1701_RS10000 a glycogen di-trans,octa-cis BN1701_RS18250 glyceraldehyde- 3-enoyl-CoA in reverse BN1701_RS23975 a peptide cofactor biosynthesis BN1701_RS14085 pyrophosphokinase: adenosylcobalamin biosynthesis from adenosylcobinamide-GDP I thiamine diphosphate 2-naphthoate BN1701_RS13130 3-acetylamino-4- an N- -undecaprenyl transaldolase: tal 3-phosphate ∆3,∆2-enoyl- a mature peptidoglycan a nascent peptidoglycan oxidized orientation DHAP D-erythrose 1-(β-D BN1701_RS14030 biosynthesis I (E. coli) polyprenyltransferase: Nα,Nε-diacetyl- hydroxybenzoate acetylarylamine sulfo-bis(guanylyl an apo-[hydroxymethylbilane diphosphate met dehydrogenase: γ a tRNA a cleaved type a peptide canavaninosuccinate ribofuranosyl) BN1701_RS24005 CoA isomerase: with (L-alanyl- -D-glutamyl- (meso-DAP containing) factor 420-0 GMP D-ala molybdopterin) thiamine undecaprenyl- 5,6-dimethylbenzimidazole 2-[(2R,5Z)- D-erythrose containing a lysyl-D-alanine IV prepilin synthase]-L-cysteine gap BN1701_RS04665 meso-2,6-diaminopimeloyl- with GlcNAc terminus FMN NADPH H + nicotinamide diphosphate methionine F6P 3' CCA end cofactor diphosphate 2-carboxy-4- 4-phosphate D-alanine) tetrapeptide adenosyltransferase: nicotinate-nucleotide-- methylthiazol-5(2H (2E)-dodec- a [hydroxymethylbilane folate polyglutamylation phosphatase: DMKH2-10 transketolase: 13-DPG BN1701_RS14250 dimethylbenzimidazole )-ylidene]ethyl 2-enoyl-CoA synthase] ES intermediate BN1701_RS09720 HMP-PP BN1701_RS17880 2 phosphoribosyltransferase: enoyl-CoA a [prokaryotic an all-trans- 2251 3''-O-acetyl- di-trans,octa-cis methionine phosphate demethylmenaquinone phosphoglycerate 3-aci- 37 guanosine D-sedoheptulose (S)-1-pyrroline- [+ 2 isozymes] Carbohydrate Degradation a ferrocytochrome palmitoyl-CoA an adenosine O-succinyl-L- 4-methylcatechol acetylxylan α-amylose hydroxymethylbilane a tetrahydrofolate -undecaprenyl adenosyltransferase: cobT methyltransferase: hydratase: ubiquitin-like protein] 1,4-dihydroxy- polyisoprenyl DMAPP in 23S rRNA ADP-ribose 1,7-bisphosphate 5-carboxylate kinase: b a [protein]-L-lysine nitropropanoate in tRNA homoserine D-glyceraldehyde 5 C-terminal L-glutamate 2-naphthoate diphosphate catechol 2,3- 23S rRNA L-glutamate 1,4-alpha- 5,6-dimethylbenzimidazole synthase: hemC phosphate BN1701_RS33330 thiamine phosphate BN1701_RS23890 BN1701_RS06300 BN1701_RS23745 α 3-phosphate Entner-Doudoroff pathway I glucan biosynthesis I (aerobic) adenosylcobinamide-GDP -ribazole 5'-phosphate synthase: (S)-3- sucrose degradation III (sucrose invertase) dioxygenase: (guanosine(2251) O-acetyl-ADP- acetylxylan gamma- a [hydroxymethylbilane serine glutathione 3-phospho- nitronate class II fructose- bifunctional SAM menaquinol-10 tRNA (adenosine(37)-N6) BN1701_RS07550 -2'-O)- semialdehyde branching synthase] ES intermediate BN1701_RS29045 hydroxydodecanoyl-CoA acyl-CoA 1,4-dihydroxy- cystathionine ribose deacetylase: esterase: 3 folylpolyglutamate hydroxymethyltransferase: biosynthesis D-glycerate D-glucopyranose Pup--protein monooxygenase: bisphosphate protein riboflavin desaturase: 2-naphthoate -dimethylallyltransferase gamma-synthase: catechol 2,3- methyltransferase BN1701_RS34675 BN1701_RS07765 dehydrogenase: BN1701_RS15490 10 adenosylcobinamide-GDP enoyl-CoA 6-phosphate sucrose ligase: pafA aldolase: fbaA bifunctional riboflavin hydroxymethylbilane synthase/ an N - phosphoglyceromutase: BN1701_RS02525 MiaA: miaA dioxygenase: RlmB: rlmB pruA GlgB: glgB thiamine hydratase/ BN1701_RS00375 polyprenyltransferase: BN1701_RS30585 2-O- kinase/FAD synthetase: synthase: hemC dihydrofolate [+ 2 isozymes] formyltetrahydrofolate cys glu ribazoletransferase: cobS BN1701_RS24310 glucose-6- [+ 3 isozymes] BN1701_RS24005 BN1701_RS07555 2251 amylopectin synthase: phosphate isomerase [+ 6 isozymes] (2Z,4E)-2-hydroxy- methylguanosine glu BN1701_RS16450 sucrase ferredoxin: 6 xylan D-erythrose a [hydroxymethylbilane bifunctional 2-phospho- family protein: phosphate N6-([prokaryotic N -(3-methylbut- acetate ADP-D-ribose acetate DHAP FMN BN1701_RS02010 a 5,10- thiamine- menaquinol-11 biosynthesis 5-methyl-6-oxohexa- in 23S rRNA synthase] ES intermediate folylpolyglutamate adenosylcobalamin 5'-phosphate dehydrogenase: BN1701_RS09825 ubiquitin-like protein]- [unspecified succinate 4-phosphate 4 D-glycerate BN1701_RS04665 2-en-1-yl)- L-homocysteine methylenetetrahydrofolate glutamate-- tetrahydrofolate salvage from phosphate kinase: 3-oxopropanoate nitrite degradation 2,4-dienoate synthase/ all-trans- zwf palmitoleoyl-CoA a ferricytochrome γ-L-glutamyl)- DMKH adenosine 37 flavin reductase: hydroxymethylbilane cysteine ligase: 5,10-methenyltetrahydrofolate BN1701_RS17335 phosphopyruvate β 2 a tetrahydrofolate bifunctional dihydrofolate adenosylcobalamin 5'- undecaprenyl 1,4-dihydroxy- 3-oxododecanoyl-CoA glucose-6-phosphate -D-fructofuranose D-glucopyranose b [protein]-L-lysine products] in tRNA BN1701_RS13130 synthase: hemC BN1701_RS00160 hydratase: eno 5 folylpolyglutamate synthase: a 5,10- phosphate phosphatase: thiamine diphosphate 2-naphthoate dehydrogenase: NADPH-dependent [+ 3 isozymes] acetyl-CoA C- a holo-[hydroxymethylbilane synthase/ BN1701_RS02010 methenyltetrahydrofolate BN1701_RS34940 diphosphate phosphoenol BN1701_RS06345 FMN reductase: ssuE bifunctional acyltransferase: synthase] dihydrofolate 10 1,4-dihydroxy- pyruvate 6-phospho a [2-oxoglutarate- a 2-oxo a very-long- DNA with adenine:7,8- an [amino-group carrier 2''-O-acetyl- 6-O-trans- a (1->4)- an N - methylenetetrahydrofolate a [DNA]-3'- a D-tryptophanyl- + synthase: γ-L-glutamyl- adenosylcobalamin 2-naphthoate BN1701_RS03895 D-glucopyranose a sulfurated dihydro-8- malonyl-CoA H protein]-C-terminal-γ- ADP-ribose protoheme methoxy-mycolyl- α-D-glucan FMNH formyltetrahydrofolate pyruvate D-glucono- SAM dehydrogenase carboxylate chain fatty acid hydroxyl Trp IMP 2 cytidylyl molybdenum dehydrogenase/ [sulfur carrier] [tRNA ] BN1701_RS02010 L-cysteine polyprenyltransferase: 1,5-lactone 6-phosphate E2 protein] N 6 - oxoguanine mismatch (L-glutamyl)-L-glutamate trehalose 6- 1,4-alpha- cofactor sulfurylation methenyltetrahydrofolate kinase: pyk decanoyl-CoA glutathione NAD BN1701_RS24005 octanoyl-L-lysine bifunctional phosphate glucan 5,6-dimethylbenzimidazole a 5,10- 6-phosphogluconolactonase: glucose-6-phosphate long-chain-acyl- type III polyketide acetylglutamate O-acetyl-ADP- trehalose- cytidylyl molybdenum synthase: cyclohydrolase: phosphorylation and lipoate biosynthesis 2-oxoacid:ferredoxin exodeoxyribonuclease ferrochelatase: metallophosphatase/ branching synthase: bluB factor 420 methylenetetrahydrofolate pyruvate acyl-CoA/acyl-ACP pgl isomerase: A/G-specific adenine D-tyrosyl-tRNA(Tyr) kinase: argB ribose deacetylase: phosphatase: 10 BN1701_RS22750 and incorporation I oxidoreductase CoA synthetase: III: xth synthase: 5'-nucleotidase: polyglutamylation cofactor (trioxo) gshB an N - transhydrogenation lipoyl glycosylase: deacylase: BN1701_RS05835 protein demethylmenaquinol- dehydrogenase: D-gluconate BN1701_RS06350 BN1701_RS26890 BN1701_RS00680 an [amino-group carrier BN1701_RS34675 otsB 5,6-dimethylbenzimidazole demethylmenaquinol- DMKH2-11 synthase: subunit beta: exodeoxyribonuclease BN1701_RS14085 trehalose- GlgB: glgB formyltetrahydrofolate NAD + BN1701_RS32540 BN1701_RS28695 BN1701_RS03935 protein]-C-terminal- oxidized 6 biosynthesis I glutathione 8 biosynthesis I an octanoyl-[acp] 6-phosphate lipA BN1701_RS23755 III: xth trans-methoxy- an [MCD cofactor phosphoribosylglycinamide demethylmenaquinone [+ 14 isozymes] F6P γ-(5-phospho-L- inosine starch factor 420-0 all-trans- all-trans- NAD kinase: phosphogluconate mono-mycolate coenzyme F420-0:L- lipoyl(octanoyl) a very-long-chain ADP-D-ribose 2+ protoporphyrin IX chaperone]-MCD demethylmenaquinol- formyltransferase: 1,4-dihydroxy- BN1701_RS14040 methyltransferase: a [2-oxoglutarate octoketide glutamyl)-L-glutamate acetate Fe glutamate ligase: hexaprenyl 1,4-dihydroxy- octaprenyl transferase (2E)-dec-2-enoyl-CoA dehydratase: D-galactose degradation I (Leloir pathway) a reduced diphosphate fatty acyl-CoA a 2'- an apurinic site BN1701_RS22800 BN1701_RS23890 5'-deoxyadenosine an unsulfurated + AMP a [DNA]-3'- Trp cysteine desulfurase: 9 biosynthesis 2-naphthoate 2-naphthoate diphosphate NADP + met dehydrogenase an acyl-CoA CO H within DNA D-tryptophan a tRNA BN1701_RS21960 diphosphate LipB: lipB BN1701_RS11050 2 ferredoxin [iron- deoxyribonucleoside adenine oxidized BN1701_RS06475 a [lipoyl-carrier protein] β-D- 6 [sulfur carrier] hydroxyl thiamine diphosphate all-trans- a tetrahydrofolate menaquinol-11 enoyl-CoA E2 protein] N sulfur] cluster 5'-monophosphate factor 420-1 NAD(P) N 6 -octanoyl-L-lysine galactopyranose thiamine RS30910 thiamine salvage III [+ 2 isozymes] nonaprenyl 1,4-dihydroxy- 1,4-dihydroxy- 1,4-dihydroxy- hydratase: KDGP -lipoyl-L-lysine F420-1:γ- a [cytidylyl molybdenum diphosphate 2-naphthoate 2-naphthoate pyridoxal 5'-phosphate biosynthesis II 2-naphthoate transhydrogenase lipoyl BN1701_RS23745 galactose cofactor chaperone]- subunit alpha: thiamine glutamyl ligase: polyprenyltransferase: polyprenyltransferase: synthase: lipA mutarotase: α trans,octacis a [TusE sulfur 4 (S)-3- GDP- -D- a [protein]- an O - all-trans- methyl β-D-glucoside GDP-α-D- thiamine cytidylyl molybdenum 1,4-dihydroxy- BN1701_RS03035 bifunctional BN1701_RS32015 a uridine 34 in tRNA (S)-2- reduced riboflavin BN1701_RS21960 BN1701_RS24005 BN1701_RS24005 a [lipoyl-carrier hydroxydecanoyl-CoA mannose -decaprenyl carrier protein]-S methylthymine dodecaprenyl 1,4-dihydroxy- glu a PII protein 6-phosphate mannose a protein L-ornithine a protein Peptide RS00520 Peptide cofactor (sulfo-dioxo) aldehydo-D-ribose D-glyceraldehyde gln 6 L-cysteine GTP pyrophosphokinase: oxidized 2-naphthoate protein]-N -[(R)- 4-hydroxy-2- α-D- phosphate -sulfanylcysteine 2-naphthoate aminobutanoate UTP flavin reductase: GDP-mannose 5-phosphate 3-phosphate menaquinol-8 biosynthesis NADPH (S)-3- in DNA diphosphate alpha-lytic protease ATP- BN1701_RS14030 polyprenyltransferase: dihydrolipoyl]-L-lysine oxoglutarate galactopyranose BN1701_RS13130 4,6-dehydratase: ornithine factor 420-2 demethylmenaquinol-6 demethylmenaquinol-8 hydroxydecanoyl- adenylate/guanylate prodomain- dependent zinc thiamine BN1701_RS24005 aldolase/2- polyprenol 6-phospho-beta- BN1701_RS05225 cyclodeaminase: pyridoxal 5'- Fatty Acid and Lipid Biosynthesis CoA dehydrogenase: galactokinase: tRNA 2- methylated-DNA-- 1,4-dihydroxy- glutamate-- [protein-PII] NADPH- cyclase domain- containing protein: metalloprotease diphosphate demethylmenaquinol-8 dehydro-3-deoxy- monophosphomannose glucosidase: BN1701_RS08355 potassium- BN1701_RS04665 galK [protein]-cysteine S- dependent FMN GDP-mannose containing protein: phosphate demethylmenaquinone thiouridine(34) 2-naphthoate cysteine ligase: uridylyltransferase: BN1701_RS07140 BN1701_RS01970 FtsH: ftsH + + phosphogluconate synthase: 4,6-dehydratase: K transporting K menaquinol-6 biosynthesis demethylmenaquinol-9 synthase: synthase methyltransferase: polyprenyltransferase: BN1701_RS00160 BN1701_RS16965 reductase: ssuE BN1701_RS00090 pro methyltransferase: palmitate biosynthesis (type II fatty acid synthase) 3-oxodecanoyl-CoA aldolase: eda α-D-galactose chitin degradation II (Vibrio) BN1701_RS10045 a peptide a peptide ATPase menaquinol-9 biosynthesis fatty acid elongation -- saturated UDP-α-D-glucose BN1701_RS30855 riboflavin BN1701_RS27370 NADP biosynthesis pdxT pdxS BN1701_RS23890 MnmA: mnmA BN1701_RS24005 [+ 3 isozymes] GDP-4-dehydro- [+ 2 isozymes] 1-phosphate β-D-glucose cyclic-GMP demethylmenaquinol-6 menaquinol-8 acetyl-CoA C- D-glyceraldehyde trans,octacis- 6-phosphate MeOH α-D-rhamnose 2+ 2+ chitin a [protein]-S- a uridylylated Cu RS14025 Cu demethylmenaquinone demethylmenaquinol-9 an acetoacetyl-[acp] acyltransferase: pyruvate decaprenylphospho- 34 NAD + an acetoacetyl-[acp] 3-phosphate GDP a 2-thiouridine a [TusE sulfur carrier a thymine in DNA γ-L-glutamyl-(S)- PLP demethylmenaquinone β methyl-L-cysteine DMK-12 PII protein methyltransferase: BN1701_RS03895 chitinase: -D-mannose in tRNA protein]-L-cysteine NAD kinase: methyltransferase: 3-oxoacyl-[acyl- type I 2-aminobutanoate BN1701_RS23890 BN1701_RS13175 BN1701_RS14040 menaquinol-6 BN1701_RS23890 carrier-protein] octanoyl-CoA glyceraldehyde- UDP- Na + RS28345 Na + NADP + menaquinol-9 reductase: fabG 3-phosphate glucose 4- a chitodextrin a 7-aminomethyl-7- a peptidoglycan dimer (meso an O 6 - acyl-CoA/acyl-ACP dehydrogenase: a [protein]- a 2-oxo + epimerase 34 glycerophosphoglycerol aci-nitroethane ammonium NAD H O L-threonine 3- DHAP L(or D)-O- a (3R)-3- dehydrogenase: deazaguanosine SAM -diaminopimelate containing) methylguanine carboxylate L-ornithine 2 cys a protein gap GalE: galE L-cysteine ATP phosphoserine hydroxybutanoyl-[acp] a 3-oxoacyl-[acp] BN1701_RS32540 in tRNA in DNA O-phosphate NAD(P)H- cystathionine phosphoserine fluoride CrcB fluoride [+ 14 isozymes] threonine-phosphate dependent glycerol- adenylate/guanylate endopeptidase 13-DPG D-alanyl-D-alanine glycerophosphodiester nitronate nitrite beta-synthase: phosphatase a chitodextrin S-adenosylmethionine:tRNA methylated-DNA-- ornithine- decarboxylase: 3-phosphate cyclase domain- La: lon carboxypeptidase/ phosphodiesterase: monooxygenase: reductase: BN1701_RS30575 SerB: serB Nucleoside and Nucleotide Biosynthesis 3-oxoacyl- (2E)-oct-2-enoyl-CoA phosphoglycerate [protein]-cysteine S- -oxo-acid BN1701_RS31800 dehydrogenase: containing protein: α-D- ribosyltransferase-isomerase: D-alanyl-D-alanine- BN1701_RS27055 BN1701_RS02525 nirB nirD (R)-1-amino- [acyl-carrier- kinase: UDP-α-D- BN1701_RS18310 methyltransferase: transaminase: BN1701_RS05360 BN1701_RS00090 fluoride CrcB fluoride enoyl-CoA glucopyranose endopeptidase: dacB 2-propanol O lanthionine serine a peptide superpathway of pyrimidine a (2E)-but-2-enoyl-[acp] protein] BN1701_RS06300 galactose BN1701_RS30855 [+ 2 isozymes] rocD [+ 3 isozymes] sn-glycerol [+ 2 isozymes] superpathway of guanosine inosine-5'-phosphate biosynthesis I 5-aminoimidazole ribonucleotide biosynthesis I hydratase: 1-phosphate -2-phosphate ribonucleotides de novo biosynthesis superpathway of adenine and guanine and guanosine salvage II reductase: 3-phosphate cyclic-AMP nucleotides de novo biosynthesis I enoyl-ACP β BN1701_RS23745 3-phospho- an epoxyqueuosine 34 a peptidoglycan with nitrite adenosine nucleotides adenosine salvage I -ketoacyl- fabG β D-glycerate phospho- -N- met in tRNA D,D cross-links (meso- D-ala a guanine in DNA a [protein]-S- glycerol sn-glycerol a proteinogenic L-glutamate-5- acetaldehyde de novo biosynthesis I AIR PRPP reductase ACP synthase: (S)-3- adenine nitrite gln sugar mutase: acetylglucosaminidase: diaminopimelate containing) methyl-L-cysteine 3-phosphate amino acid semialdehyde hydrogencarbonate 5-(carboxyamino)imidazole guanosine FabI: fabI BN1701_RS15155 a (3R)-3- hydroxyoctanoyl-CoA phosphoglyceromutase: IMP adenosine a 2,3,4-saturated BN1701_RS22375 N,N'- BN1701_RS28290 N,N',N''- IMP ribonucleotide synthase: amidophosphoribosyltransferase: hydroxyacyl-[acyl- enoyl-CoA BN1701_RS24310 asp purine-nucleoside a butanoyl-[acp] fatty acyl-[acp] phosphomannomutase/ diacetylchitobiose triacetylchitotriose BN1701_RS22120 BN1701_RS25270 carrier protein] hydratase/ 2-phospho- glutamine- IMP phosphorylase: phosphoglucomutase: N-acetyl-β- an (S-diacyl-sn- 34 a thiocarboxylated all-trans- 5-(methylsulfanyl) N5-CAIR β isomerase an L-1- a sulfurated [CysO sulfur- a uridine sn-glycero-3- 3-amino-4- a double an L-glutamyl- hydrolyzing dehydrogenase: BN1701_RS22370 5-phospho- - gly β-ketoacyl- D-glycerate BN1701_RS21925 glyceryl)-L-cysteinyl- [SAMP] C- tridecaprenyl 1,4-dihydroxy- leukotriene-D4 -2,3-dioxopentyl guanine glucosaminidase: phosphatidylethanolamine in tRNA phosphoethanolamine hydroxybenzaldehyde D-lysine stranded DNA Gln cys a protein adenylosuccinate D-ribosylamine family protein: phosphopyruvate [sulfur carrier] carrier protein] arylamine N- [tRNA ] carbamoyl- guaB 5-(carboxyamino)imidazole adenine ACP synthase: D-glucopyranose BN1701_RS28290 [apolipoprotein] terminal glycine diphosphate 2-naphthoate lysine 5,6- type II site-specific Asp-tRNA(Asn) 1-phosphate synthase: BN1701_RS04665 hydratase: eno acetyltransferase: cystathionine phosphate ribonucleotide mutase: purE BN1701_RS15155 6-phosphate N-acetyl-D- aminomutase deoxyribonuclease: /Glu-tRNA(Gln) acireductone proteasome BN1701_RS25480 phosphoribosylamine- apolipoprotein N- glycerophosphodiester membrane BN1701_RS10000 beta-synthase: synthase: XMP adenine hypoxanthine 3-oxooctanoyl-CoA phosphoenol glucosamine adenylyltransferase/ tRNA 2- 1,4-dihydroxy- subunit alpha: BN1701_RS29380 amidotransferase: synthase: mtnC ATPase: arc -glycine ligase: purD a 3-oxohexanoyl-[acp] acyltransferase: lnt phosphodiesterase: dipeptidase: BN1701_RS30575 carB carA CAIR phosphoribosyltransferase: phosphoribosyltransferase: hpt pyruvate sulfurtransferase thiouridine(34) 2-naphthoate arylamine N- BN1701_RS06980 a double gatB gatA gatC 1,2-dihydroxy-5- BN1701_RS14530 acetyl-CoA C- BN1701_RS09980 BN1701_RS04230 an L-glutaminyl- an unfolded glutamine- adenylo-succinate apolipoprotein N- MoeZ: moeZ synthase polyprenyltransferase: acetyltransferase: (2R,5S)-2,5- stranded DNA (methylsulfanyl) ser 3-oxoacyl-[acyl- pyruvate [+ 2 isozymes] Gln protein carbamoyl hydrolyzing GMP phosphoribosylaminoimidazolesuccinocarboxamide GAR acyl-CoA/acyl-ACP a trans-2- acyltransferase: acyltransferase: lnt MnmA: mnmA BN1701_RS23975 diaminohexanoate with 5'-terminal [tRNA ] pent-1-en-3-one asp GMP carrier-protein] a 2,3,4-saturated kinase: pyk (1,4)-β-D-xylan BN1701_RS24005 phosphate synthase: guaA adenylosuccinate synthase: BN1701_RS25380 AMP dehydrogenase: enoyl-[acyl- BN1701_RS03895 3-acetylamino-4- phosphate phosphoribosylglycinamide reductase: fabG fatty acyl-[acp] degradation a [CysO sulfur- leukotriene-E4 lyase: guanine and guanosine salvage BN1701_RS00065 an N-acyl-(S-diacyl- an unsulfurated 34 gly hydroxybenzaldehyde carrier protein] hexanoyl-CoA pyruvate a 2-acyl-1-lyso- carrier protein]- a [SAMP] C- a 2-thiouridine sn-glycerol BN1701_RS25395 SAICAR formyltransferase: sn-glyceryl)-L- [sulfur carrier] ethanolamine aspartate GMP a (3R)-3- [+ 10 isozymes] β phosphatidylethanolamine terminal glycine in tRNA 3-phosphate DMKH2-13 BN1701_RS22800 a (1->4)- -D-xylan cysteinyl-[lipoprotein] thiocarboxylate carbamoyltransferase hydroxyhexanoyl-[acp] acyl-CoA/acyl-ACP adenylosuccinate lyase: chitobiose degradation catalytic subunit: AMP pyrimidine deoxyribonucleotides de novo biosynthesis III FGAR guanosine dehydrogenase: guanylate BN1701_RS25395 purine-nucleoside enoyl-ACP a (1->4)-β-D-xylan BN1701_RS14300 BN1701_RS32540 adenine 2503 a methylated a [protein]- a DNA methyl a peptidoglycan β-D-fructofuranose a guanine 527 a [protein]-L- a uracil 1498 6-O-cis-methoxy- kinase: gmk reductase N,N'-diacetylchitobiose oligosaccharide an alkylated DNA 3'-ketolactose UDP CTP phosphoribosylformylglycinamidine phosphorylase: CDP-diacylglycerol [+ 14 isozymes] 2-oxoglutarate nucleobase dimer (S. aureus) 1-phosphate ω mycolyl-trehalose a protein adenylate kinase: AICAR FabI: fabI in 23S rRNA L-cysteine phosphotriester in 16S rRNA proline ( = 180) in 16S rRNA GTP ribonucleoside- BN1701_RS22370 biosynthesis I 6'-phosphate beta-xylosidase: 16S rRNA 6-phosphate N-carbamoyl- synthase: purL purQ purS within DNA FKBP-type 16S rRNA BN1701_RS23280 bifunctional guanine a (2E)-hex-2-enoyl-[acp] (2E)-hexenoyl-CoA trehalose- GDP diphosphate reductase: BN1701_RS14335 D-alanyl-D-alanine (guanine(527)-N(7) peptidyl-prolyl cis- (uracil(1498)-N(3))- diguanylate cyclase: proteasome: L-aspartate CDP DHAP 23S rRNA methylated-DNA-- DNA-3- beta-glucosidase: class II fructose- phosphatase: phosphoribosylaminoimidazolecarboxamide BN1701_RS13560 FGAM N-monoacetylchitobiose alpha-ketoglutarate- )-methyltransferase trans isomerase: methyltransferase: BN1701_RS36675 prcB prcA ADP enoyl-ACP NAD(P)H- enoyl-CoA β-D-xylopyranose (adenine(2503)-C(2) [protein]-cysteine S- carboxypeptidase/ methyladenine BN1701_RS13745 bisphosphate otsB formyltransferase/IMP cyclohydrolase: purH BN1701_RS13565 6'-phosphate dependent RsmG: rsmG BN1701_RS05985 BN1701_RS02675 dihydroorotase: ribonucleoside- hypoxanthine reductase hydratase: D-alanyl-D-alanine- beta-glucosidase: aldolase: fbaA an N 7 - an N 3 - [+ 4 isozymes] trehalose- dUDP phosphoribosylformylglycinamidine dependent glycerol- long-chain fatty 6-phospho-beta- )-methyltransferase methyltransferase: glycosylase: ribonucleoside- ribonucleoside- dioxygenase AlkB: 527 [+ 7 isozymes] 1498 cis-methoxy- BN1701_RS14295 nucleoside- FAICAR diphosphate reductase: phosphoribosyltransferase: hpt FabI: fabI 3-phosphate BN1701_RS23745 RlmN: rlmN BN1701_RS30855 endopeptidase: dacB BN1701_RS14090 BN1701_RS17820 methylguanine methyluracil c-di-GMP a peptide diphosphate cyclo-ligase: BN1701_RS25265 acid activation glucosidase: BN1701_RS10835 a [protein]-L- diphosphate diphosphate nucleoside- BN1701_RS13560 dehydrogenase: (S)-3- in 16S rRNA in 16S rRNA mono-mycolate (S)-dihydroorotate reductase: a long-chain BN1701_RS07140 proline (ω = 0) kinase: ndk reductase: bifunctional diphosphate kinase: ndk BN1701_RS13565 a hexanoyl-[acp] β DHAP D-glyceraldehyde AIR GMP BN1701_RS05360 hydroxyhexanoyl-CoA 2503 a peptidoglycan a DNA containing 3-keto- -D- BN1701_RS13560 BN1701_RS13560 fatty acid N-acetyl-D-glucosamine a 2-methyladenine a [protein]-S- an alkylated D-glucopyranose phosphoribosylaminoimidazolecarboxamide dUTP dCDP sn-glycerol acyl-CoA 5'-deoxyadenosine formaldehyde a nucleobase succinate [DNA] with D,D cross- D-ala galactose quinone-dependent BN1701_RS13565 β 3-hydroxyhexanoyl- 6-phosphate in 23S rRNA met methyl-L-cysteine nucleobase an apurinic/ BN1701_RS13565 formyltransferase/IMP cyclohydrolase: purH superpathway of pyrimidine deoxyribonucleoside salvage -ketoacyl- 3-phosphate synthetase: within DNA link (S. aureus) dihydroorotate dUTP diphosphatase: dut nucleoside- CoA dehydrogenase: apyrimidinic site GTP ACP synthase: BN1701_RS00320 dehydrogenase: nucleotide diphosphate kinase: ndk BN1701_RS04665 dADP IMP 2'-deoxycytidine BN1701_RS15155 [+ 10 isozymes] BN1701_RS16155 pyrophosphohydrolase: a long-chain 38- dGDP dCTP adenine and adenosine salvage III 3-oxohexanoyl-CoA 5-methoxy-6- (S)-5-amino-3- a peptidoglycan a negatively a guanine 966 a uridine 3-oxo-23,24- 6-O-trans-keto- PRPP BN1701_RS27280 a 3-oxooctanoyl-[acp] a 1-acyl-sn fatty acyl-CoA NaMN 3-methylbutanoate acetyl-CoA 1,4-dihydroxy- GGPP a sphingomyelin bisnorchol-4- roseoflavin mycolyl-trehalose 5-hydroxy- orotate nucleoside- nucleoside CMP Amine and Polyamine Degradation methylbenzimidazole oxohexanoate dimer (generic) supercoiled DNA in 16S rRNA 40 in tRNA -glycerol 3- acetyl-CoA C- 2-naphthoate DNA topoisomerase 16S rRNA RluA family en-22-oyl-CoA bifunctional 6-phosphate L-tryptophan nucleoside- diphosphate dUMP deaminase: phosphorylation aromatic 3-oxoacyl-[acyl- phosphate acetyltransferase: 4 subunit A: (guanine(966)-N(2) pseudouridine 3-oxosteroid 1- riboflavin kinase/ trehalose- orotate diphosphate kinase: ndk BN1701_RS11260 dCMP adenine superpathway of N-acetylglucosamine, 3-keto-5- endolytic sphingomyelin amino FAD-dependent CMP carrier-protein] 1-acyl-sn-glycerol- BN1701_RS16200 allantoin degradation nicotinate-nucleotide-- acetate--CoA ligase: acs 1,4-dihydroxy- BN1701_RS11540 )-methyltransferase synthase: dehydrogenase: FAD synthetase: phosphatase: phosphoribosyltransferase: kinase: ndk [+ 3 isozymes] purine-nucleoside N-acetylmannosamine and N- aminohexanoate transglycosylase phosphodiesterase: acid lyase: superpathway of pyrimidine thymidylate synthase: (d)CMP kinase: (d)CMP kinase: reductase: fabG 3-phosphate [+ 8 isozymes] to ureidoglycolate dimethylbenzimidazole acetate--CoA ligase: acs 2-naphthoate RsmD: rsmD BN1701_RS09890 BN1701_RS21355 BN1701_RS16450 otsB BN1701_RS25705 dATP phosphorylase: acyl-CoA hydrolysis acetylneuraminate degradation MltG: mltG type I DNA 2 3-oxo-23,24- trehalose- cmdF nucleobases salvage BN1701_RS16320 BN1701_RS27905 BN1701_RS27905 acyltransferase: phosphoribosyltransferase: cleavage protein: BN1701_RS32370 an N - roseoflavin 2'-deoxyuridine BN1701_RS22370 a (3R)-3- I (urea producing) polyprenyltransferase: topoisomerase: 966 [+ 2 isozymes] bisnorchol-1,4- trans-keto- dGTP BN1701_RS25215 [+ 2 isozymes] methylguanine 38- serotonin (d)CMP kinase: (d)CMP kinase: BN1701_RS03490 butanoyl-CoA N-acetylneuraminate cobT BN1701_RS24005 a pseudouridine 5'-phosphate orotidine 5'- uracil dTMP adenosine hydroxyoctanoyl-[acp] a 2,3,4-saturated (S)-(+)-allantoin topA in 16S rRNA dien-22-yl-CoA mono-mycolate BN1701_RS12070 BN1701_RS12070 [+ 7 isozymes] 40 in tRNA phosphate bifunctional pyr operon thymidine kinase: fatty acyl CoA acyl-CoA/acyl-ACP 3-methylbutanoyl-CoA diphosphate a ceramide phosphocholine a relaxed DNA thymidylate kinase: CDP a 1,2-diacyl- acyl-CoA allantoinase 5-methoxy-6- AMP GlcNAc-1,6- transcriptional regulator/uracil BN1701_RS10025 adenosine deaminase: add N-acetyl-D- (S)-3- a lipid II BN1701_RS33850 dCDP sn-glycerol thioesterase: dehydrogenase: AllB: allB methylbenzimidazole nicotinate acetoacetate anhydro-MurNAc- orotidine-5'- phosphoribosyltransferase adenosine deaminase: nucleoside- mannosamine aminobutanoyl-CoA demethylmenaquinol-4 dTMP kinase: thymidine nucleoside- 3-phosphate BN1701_RS01770 BN1701_RS32540 allantoate ribotide phosphate pentapeptide phosphate PyrR: pyrR xanthine and dUMP BN1701_RS22515 diphosphate allantoin degradation BN1701_RS21870 diphosphate phosphatidate [+ 4 isozymes] [+ 14 isozymes] decarboxylase: pyrimidine ribonucleosides salvage I xanthosine salvage kinase: ndk a (2E)-oct-2-enoyl-[acp] a 2,3,4-saturated to ureidoglycolate II uracil thymidine kinase: kinase: ndk cytidylyltransferase: allantoicase: pyrF dTDP inosine fatty acid crotonyl-CoA (ammonia producing) a uridine 34 a [protein]- phosphoribosyltransferase: upp BN1701_RS10025 CTP BN1701_RS16835 N-acetyl-D- alc 5-methoxybenzimidazole NaMN a β-D-galactoside a [protein]-S- a peptide with a a D-aminoacyl- 3-methylcatechol N-formimino- an L-aspartyl- cytidine dCTP enoyl-ACP canavaninosuccinate thr ser trp UMP UMP nucleoside- mannosamine sulfanyl-L-cysteine in tRNA [tRNA] [tRNA Asn ] L-histidine xanthosine reductase a CDP- enoyl-CoA (S)-(+)-allantoin leader sequence catechol 2,3- L-glutamate diphosphate kinase: ndk purine-nucleoside 6-phosphate (S)-ureidoglycolate Asp-tRNA(Asn) threonine/serine histidine kinase: threonine/serine aromatic UMP kinase: UMP kinase: purine-nucleoside FabI: fabI diacylglycerol hydratase: allantoinase dioxygenase: formimidoylglutamate nucleoside uridine kinase: phosphorylase: N-acetylmannosamine- beta-glucosidase: /Glu-tRNA(Gln) dehydratase: BN1701_RS06630 dehydratase: amino BN1701_RS16845 BN1701_RS16845 dTTP phosphorylase: BN1701_RS23745 AllB: allB nicotinate-nucleotide-- tRNA 2- BN1701_RS07550 deiminase: deaminase: BN1701_RS14405 dTMP BN1701_RS22370 6-phosphate BN1701_RS13745 signal peptidase I: D-tyrosyl-tRNA(Tyr) argininosuccinate amidotransferase: BN1701_RS10660 [+ 4 isozymes] BN1701_RS10660 acid lyase: UDP BN1701_RS22370 an octanoyl-[acp] (S)-3- allantoate dimethylbenzimidazole thiouridine(34) BN1701_RS21625 UDP BN1701_RS11260 uridine kinase: xanthine 2-epimerase: BN1701_RS08420 deacylase: catechol 2,3- lyase: argH gatB gatA gatC a [protein]- cmdF thymidylate kinase: triacylglycerol hydroxybutanoyl-CoA phosphoribosyltransferase: beta-glucosidase: synthase N-formyl- an L-asparaginyl- [+ 2 isozymes] [+ 3 isozymes] [+ 3 isozymes] BN1701_RS15875 nucleoside- hypoxanthine β BN1701_RS07805 BN1701_RS03935 dioxygenase: N-phospho- BN1701_RS33850 -ketoacyl- allantoate BN1701_RS17820 [+ 4 isozymes] Asn pyruvate tryptamine nucleoside- biotin-carboxyl carrier degradation (S)-3- cobT MnmA: mnmA L-glutamate [tRNA ] 2-oxobutanoate L-histidine diphosphate kinase: ndk ACP synthase: N-acetyl-D- amidohydrolase: BN1701_RS07555 diphosphate dTMP kinase: protein assembly hydroxybutanoyl- (2Z,4E)-2-hydroxy-6- uridine CMP BN1701_RS15155 a triacyl-sn glucosamine BN1701_RS21630 L-canavanine fumarate kinase: ndk UTP BN1701_RS21870 hypoxanthine 34 an uncharged oxohepta-2,4-dienoate a [biotin carboxyl- -glycerol CoA dehydrogeanse: 6-phosphate D-galactopyranose a non galactosylated a [protein]- a 2-thiouridine gln uridine kinase: phosphoribosyltransferase: hpt triacylglycerol lipase: 5-methoxybenzimidazole nicotinate a leader sequence a peptide a D-amino acid UTP CTP synthase: dTDP BN1701_RS04665 N-acetylglucosamine- (S)-ureidoglycine galactose acceptor L-cysteine in tRNA tRNA a 3-oxodecanoyl-[acp] carrier protein]-L-lysine BN1701_RS30015 ribotide phosphate BN1701_RS14405 XMP 6-phosphate BN1701_RS14015 nucleoside- biotin--[acetyl-CoA- a 1,2-diacyl- uridine kinase: acetoacetyl-CoA deacetylase: nagA CTP synthase: CTP diphosphate IMP 3-oxoacyl-[acyl- carboxylase] ligase: sn-glycerol BN1701_RS14015 BN1701_RS15875 46 4-(2'- kinase: ndk carrier-protein] BN1701_RS22190 acetyl-CoA C- D-glucosamine lysine within O-succinyl-L- a triacyl-sn a guanine dCDP 5-hydroxybenzimidazole NaMN an octanoyl-[acp] isobutanoate cys adenosylcobinamide [DNA] carboxyphenyl)- a dipeptide methylglyoxal tyr UMP reductase: fabG a [biotin carboxyl- acetyltransferase: 6-phosphate gcv protein H homoserine -glycerol in tRNA ribonucleoside- CTP dTTP (S)-ureidoglycolate bifunctional bifunctional 3'- tRNA 4-oxobutyryl-CoA glyoxalase: a (3R)-3- carrier protein]-N BN1701_RS30565 1,4-dihydroxy- membrane diphosphate aromatic 6 adenosylcobinamide 5' exonuclease/ (guanosine(46)-N7) BN1701_RS05715 hydroxydecanoyl-[acp] -biotinyl-L-lysine a 2-acylglycerol [+ 8 isozymes] 2-naphthoyl- dipeptidase: reductase: amino nicotinate-nucleotide-- lipoyl(octanoyl) acetate--CoA ligase: acs kinase/ triacylglycerol lipase: DNA polymerase: -methyltransferase glyoxalase: α dimethylbenzimidazole cystathionine CoA synthase: BN1701_RS04230 BN1701_RS13560 acid lyase: -D-glucosamine transferase acetate--CoA ligase: acs adenosylcobinamide- BN1701_RS30015 BN1701_RS00315 TrmB: trmB BN1701_RS13530 acetyl-CoA gamma-synthase: an N 7 - BN1701_RS23970 a proteinogenic BN1701_RS13565 cmdF Secondary Metabolite Biosynthesis 6-phosphate phosphoribosyltransferase: LipB: lipB phosphate [+ 6 isozymes] 1,4-dihydroxy-2- a [biotin carboxyl- BN1701_RS30585 a 2'- methylguanine 46 amino acid (R)-lactate p-tyramine Carbohydrate Biosynthesis cobT guanylyltransferase: naphthoyl-CoA CDP carrier-protein dimer]- a [glycine-cleavage deoxyribonucleoside in tRNA glycerol BN1701_RS03265 a diacyl-sn methylerythritol phosphate pathway I methylerythritol phosphate pathway II a (2E)-dec-2-enoyl-[acp] 6 isobutanoyl-CoA a fatty acid myo-inositol biosynthesis N -biotinyl-L-lysine acyl-carrier protein complex H protein] diphosphate -glycerol 5'-monophosphate glycogen biosynthesis III (from α-maltose 1-phosphate) preQ biosynthesis 5-hydroxybenzimidazole AMP succinate adenosyl-cobinamide α 0 acetyl-CoA nicotinate N 6 -octanoyl-L-lysine L-cystathionine UDP-N-acetyl-D- glycogen biosynthesis I (from ADP-D-Glucose) UDP- -D-galactofuranose D-glyceraldehyde D-glyceraldehyde enoyl-ACP F6P ribotide phosphate phosphate pyruvate pyruvate D-glucopyranose carboxylase Nucleoside and Nucleotide Degradation D-glucopyranose glucosamine biosynthesis I GDP-mannose biosynthesis biosynthesis 3-phosphate 3-phosphate reductase acetyl-CoA ADP-α-D-glucose D-glucopyranose 6-phosphate carboxyltransferase 6-phosphate D-glucopyranose GTP inositol-3-phosphate FabI: fabI carboxylase 6-phosphate D-glucopyranose UDP-α-D-glucose subunit: 1-deoxy-D-xylulose- GTP synthase: biotin superpathway of pyrimidine an 1-acyl-2- an (R)-2- a [protein] N-terminal- guanine 37 a supercoiled UDP 6-phosphate UDP-glucose 4- 1-deoxy-D-xylulose- BN1701_RS04625 ARP 5-aminolevulinate a steryl-ester a ribonucleoside enterobactin precorrin-6B glucose-6-phosphate 6-phosphate tyr SAM CDP-choline Phe phospho- glucose-6-phosphate 5-phosphate 5-phosphate cyclohydrolase BN1701_RS13815 a decanoyl-[acyl-carrier protein] carboxylase deoxyribonucleosides degradation arachidonoyl- halocarboxylate formyl-L-methionine diphosphate in tRNA duplex DNA ribonucleoside- L-dopa isomerase: epimerase GalE: galE 7,8- acetyl-CoA ATP-dependent sugar mutase: isomerase: UDP-α-D-galactose synthase: synthase: I FolE: folE inositol-3-phosphate subunit: accC superpathway of purine deoxyribonucleosides degradation sn-glycerol ribonucleoside- tRNA enterochelin precorrin-6y C5,15- diphosphate aromatic BN1701_RS06350 dihydroneopterin β carboxylase: 2'-deoxycytidine helicase: BN1701_RS22375 BN1701_RS06350 BN1701_RS04145 BN1701_RS04145 synthase: -ketoacyl- diphosphate (guanosine(37)-N1) esterase: methyltransferase reductase: amino F6P UDP-galactopyranose 3'-triphosphate BN1701_RS23070 chloramphenicol HAD family peptide cholesterol esterase: BN1701_RS03610 trehalose-6- phosphomannomutase/ F6P BN1701_RS26215 ACP synthase: bifunctional FO acyl--CoA ligase: reductase: -methyltransferase BN1701_RS05230 (decarboxylating) BN1701_RS13560 acid lyase: mutase: glf 1-deoxy-D-xylulose- 1-deoxy-D-xylulose- a [carboxyl-carrier nucleoside phosphotransferase hydrolase: deformylase: def phosphate synthase: phosphoglucomutase: 6-carboxytetrahydropterin BN1701_RS15155 2'-deoxyguanosine biosynthesis protein BN1701_RS20830 BN1701_RS17325 BN1701_RS13560 1 TrmD: trmD N-(2,3- [+ 6 isozymes] subunit CbiE: cbiE glutamine-- 5-phosphate 5-phosphate Ins(3)P 6 deaminase: BN1701_RS01205 an N - BN1701_RS13565 cmdF BN1701_RS28875 mannose-6- synthase: protein dimer]-N - CPT: cpt peptide deformylase: dihydroxybenzoyl) a single BN1701_RS21925 UDP-Galf CofGH: BN1701_RS10915 a 2'- BN1701_RS13565 methylguanine 37 precorrin-8x dopamine fructose-6- phosphate synthase: synthase: a 3-oxododecanoyl-[acp] carboxybiotinyl-L-lysine BN1701_RS11260 thymidine 2'-deoxyadenosine [+ 6 isozymes] BN1701_RS29090 stranded DNA dUDP α-D- BN1701_RS00445 Phe -L-serine phospho- phosphate BN1701_RS30960 BN1701_RS30960 inositol [+ 3 isozymes] a 1-acyl-2- 5-aminolevulinyl- deoxyribonucleoside in tRNA glucopyranose isomerase, [+ 2 isozymes] thymidine CMP a fatty acid a sterol sugar mutase: transaminase monophosphatase: 3-oxoacyl-[acyl- purine-nucleoside 5-amino-5-(4-hydroxybenzyl)-6- arachidonoyl- CoA diphosphate 5'-diphosphate class I: manA 6-carboxy-5,6,7,8- 5'-deoxyadenosine 2-iminoacetate AMP an (S)-2- (isomerizing) 1-phosphate 1-deoxy-D-xylulose 1-deoxy-D-xylulose BN1701_RS04050 2'-deoxyuridine phosphorylase: (D-ribitylimino)-5,6-dihydrouracil met a halide anion formate an N-terminal L- BN1701_RS22375 D-mannopyranose carrier-protein] adenosine phosphorylase: phosphatidylcholine glucose-1-phosphate PRPP biosynthesis 5-phosphate 5-phosphate tetrahydropterin BN1701_RS22545 hydroxycarboxylate methionyl-[protein] phosphomannomutase/ α α : glmS inositol reductase: fabG deaminase: add BN1701_RS22370 , -trehalose adenylyltransferase: 6-phosphate 7-carboxy-7- purine-nucleoside phosphoglucomutase: glutamine-- 1-deoxy-D-xylulose- 1-deoxy-D-xylulose- monophosphatase: thymine adenosine 6-phosphate glgC phosphomannomutase/ D-ribose 5- deazaguanine a (3R)-3- phosphorylase: BN1701_RS21925 5-phosphate 5-phosphate BN1701_RS23905 fatty acid biosynthesis UDP-N-acetyl- decaprenyl-diphospho-N- RNase III mRNA 37 trehalose- fructose-6- a (1->4)- phosphoglucomutase: phosphate hydroxydodecanoyl-[acp] uracil phosphorylase: deaminase: a 1-acyl,2-oleoyl- an (S)-2- a ribonucleoside a [release factor]- a guanine a supercoiled ADP-α-D-glucose ribose-phosphate reductoisomerase: reductoisomerase: synthase QueE: initiation (type II) BN1701_RS22370 α-D-glucosamine acetylmuramoyl-pentapeptide CDP-choline processing a single ergosteryl oleate (S)-5-hydroxyisourate propionamide DNA with lesion histidinol phosphatase: phosphate α-D-glucan BN1701_RS21925 myo-inositol BN1701_RS22545 BN1701_RS22515 sn-glycerol halocarboxylate triphosphate L-glutamine in tRNA duplex DNA diphosphokinase: BN1701_RS16775 BN1701_RS01175 purine-nucleoside stranded DNA transaminase α BN1701_RS16775 substrate peptide chain tRNA ATP-dependent amidase: excinuclease histidinol otsB glycogen -D-mannose 7-carboxy-7- acetyl-CoA phosphorylase: hydroxyisourate (isomerizing) BN1701_RS30265 undecaprenyldiphospho- release factor (guanosine(37)-N1) DNA helicase: BN1701_RS03505 ABC subunit dehydrogenase: synthase: 1-phosphate PRPP MEP MEP deazaguanine acetyl-CoA carboxylase BN1701_RS22370 chloramphenicol HAD family hydrolase: uraH α,α-trehalose : glmS α muramoylpentapeptide beta-N- DNA primase: cholesterol esterase: N(5)-glutamine -methyltransferase BN1701_RS33450 UvrB: uvrB hisD glgA carboxyltransferase uracil 2-deoxy- - 2'-deoxyinosine 2-deoxy-α-D-ribose 1-phosphate phosphotransferase ribonuclease III: hydrolase: [+ 2 isozymes] 7-cyano-7- acetylglucosaminyltransferase: BN1701_RS02825 BN1701_RS17325 methyltransferase: 1 TrmD: trmD (S)-2-oxo-4- [+ 4 isozymes] [+ 5 isozymes] D-glucosamine a (1->4)- a (2E)-dodec-2-enoyl-[acp] D-ribose 1- BN1701_RS17090 an N - maltose alpha-D- 2-C-methyl-D- 2-C-methyl-D- subunit: BN1701_RS04625 CPT: cpt BN1701_RS01205 prmC hydroxy-4-carboxy- a single propanoate DNA without his 6-phosphate α-D-glucan deazaguanine phosphate murG [+ 3 isozymes] methylguanine 37 glucosyltransferase: α erythritol 4-phosphate erythritol 4-phosphate acetyl-CoA carboxylase: [+ 6 isozymes] a [release factor]-N 5 stranded DNA lesion GDP- -D- synthase enoyl-ACP in tRNA 5-ureidoimidazoline treS phosphoglucosamine 1,4-alpha- cytidylyltransferase: cytidylyltransferase: a 1-acyl-2-oleoyl- -methyl-L-glutamine α mannose QueC: queC reductase BN1701_RS23070 CMP RNase III ergosterol oleate -D- mutase: glucan BN1701_RS28775 BN1701_RS28775 decaprenyl-pyrophosphoryl- UDP sn-glycero-3- ssDNA/pppN(pN) maltose alpha-D- FabI: fabI malonyl-CoA an mRNA fragment processing an (S)-2- glucopyranose BN1701_RS23125 branching 4-(cytidine 5'- 4-(cytidine 5'- 7-cyano-7- 2-deoxy-D-ribose 5-phosphate (N-acetylglucosamine)-N- hybrid ADP-α-D-glucose glucosyltransferase: 2-deoxy-D-ribose phosphocholine a halide anion n -1 1-phosphate α deazaguanine acetylmuramyl-(pentapeptide) product mRNA hydroxycarboxylate treS -D-glucosamine protein diphospho)-2-C- diphospho)-2-C- a dodecanoyl-[acp] ACP S-malonyltransferase: 5-phosphate 1-phosphate GlgB: glgB methyl-D-erythritol methyl-D-erythritol synthase: BN1701_RS03120 deoxyribose- α-maltose-1- α 4-(cytidine 5'- BN1701_RS01185 -maltose bifunctional UDP-N- UDP-α-D-glucose 4-(cytidine 5'- deoxyribose- phosphate a [glycine-cleavage 1,2-dipalmitoyl- an (S)-2- a single- an N-terminal L- (3Z)-hex- a (2E,4Z)-2,4- phosphate a glycogen dTDP-β-L-rhamnose diphospho)- CDP-choline methanethiol O-succinyl-L- tributyrin trans-aconitate chorismate acryloyl-CoA CAIR acetylglucosamine biosynthesis diphospho)- preQ β-ketoacyl- a malonyl-[acp] phosphate aldolase: deoC a sulfurated [sulfur carrier] SAM complex H protein] sn-glycerol halocarboxylate stranded RNA alanyl-[S18 protein 3-en-1-ol dienoyl-CoA synthase: biosynthesis 2-C-methyl-D- 0 6 homoserine maltokinase: diphosphorylase/ 2-C-methyl-D- ACP synthase: aldolase: N -octanoyl-L-lysine of 30S ribosome]ribosomal protein trans-aconitate 2- CHAT domain- NADPH-dependent isochorismate crotonyl-CoA 5-(carboxyamino) glgA α D-glucopyranose erythritol kinase: BN1701_RS18490 glucosamine-1- -D-glucopyranose erythritol kinase: BN1701_RS15155 ketoacyl-ACP synthase S18-alanine N- containing protein: 2,4-dienoyl- carboxylase/ imidazole deoC acetaldehyde D-glyceraldehyde 3-phosphate chloramphenicol polyribonucleotide methyltransferase: synthase: 1-phosphate 6-phosphate BN1701_RS30195 BN1701_RS30195 laurate III: BN1701_RS33250 cystathionine HAD family triacylglycerol lipase: BN1701_RS07690 CoA reductase: reductase: ribonucleotide phosphate N- phospho- nucleotidyltransferase: acetyltransferase: BN1701_RS02835 BN1701_RS29610 α glucose-1-phosphate 2-phospho-4-(cytidine 2-phospho-4-(cytidine [+ 3 isozymes] lipoyl phosphotransferase gamma-synthase: hydrolase: -maltose 1- acetyltransferase sugar mutase: D-glyceraldehyde acetaldehyde BN1701_RS30015 an N-terminal N-acetyl-rimI (E)-3- [+ 10 isozymes] BN1701_RS29780 ccrA mutase: purE thymidylyltransferase 5'-diphospho)-2-C- 5'-diphospho)-2-C- long-chain fatty acetaldehyde synthase: lipA CPT: cpt BN1701_RS30585 BN1701_RS01205 BN1701_RS16430 (3Z)-hex-3- a (2E)-2- isochorismate (R)-methylmalonyl- phosphate GlmU: glmU BN1701_RS22375 a 3-oxotetradecanoyl-[acp] 3-phosphate (methoxycarbonyl) AIR RfbA: rfbA methyl-D-erythritol methyl-D-erythritol acid--CoA ligase: dehydrogenase L-alanyl-[S18 protein α an acetoacetyl-[acp] [+ 6 isozymes] pent-2-enedioate en-1-yl acetate enoyl-CoA CoA alpha-1,4-glucan-- N-acetyl- -D- phosphomannomutase/ 2-C-methyl-D- 3-oxoacyl-[acyl- BN1701_RS29690 acetaldehyde (acetylating): 1,2-dipalmitoyl- of 30S ribosome] glucose-1-phosphate 2-C-methyl-D- a [glycine-cleavage CMP a single- maltose-1-phosphate glucosamine phosphoglucomutase: erythritol 2,4- [+ 10 isozymes] dehydrogenase BN1701_RS07600 pyrimidine deoxyribonucleotides succinate a nucleoside butanoate 1,2-dibutyrin erythritol 2,4- carrier-protein] 5'-deoxyadenosine 6 an unsulfurated sn-glycero-3- met 1-phosphate thymidylyltransferase met complex H protein] N a (2R)-2- diphosphate stranded RNA maltosyltransferase: α BN1701_RS21925 cyclodiphosphate cyclodiphosphate reductase: fabG (acetylating): [+ 2 isozymes] dephosphorylation [sulfur carrier] phosphocholine a halide anion RfbA: rfbA -D-glucopyranose -[(R)-lipoyl]-L-lysine hydroxy fatty acid BN1701_RS13435 bifunctional UDP-N- dTDP-α-D-glucose synthase: synthase: lauroyl-CoA BN1701_RS07600 nucleotide 1-phosphate a (3R)-3- acetyl-CoA alpha-1,4-glucan-- acetylglucosamine BN1701_RS28770 [+ 2 isozymes] pyrophosphohydrolase: dTDP-glucose 4,6- UTP--glucose- BN1701_RS28770 hydroxytetradecanoyl-[acp] diphosphorylase/ phosphatidylserine and BN1701_RS27280 α maltose-1-phosphate 2-C-methyl-D-erythritol- a 1-palmitoyl-2- a 2,3,4-saturated an (R)-2- a cytidine 1402 (indol-3-yl) a (2E,4E)-2,4- 6-O- -mycolyl- dehydratase: rfbB 1-phosphate 2-C-methyl-D-erythritol- acetyl-CoA dCTP dCMP a [pyruvate dehydrogenase E2 CDP-choline (2E,6E)-farnesyl a cytosine in DNA maltosyltransferase: glucosamine-1- phosphatidylethanolamine 6 1,2-diacyl-sn- lanosteryl oleate oxaloacetate wound RNA dTDP-4-dehydro-6- uridylyltransferase: 2,4-cyclodiphosphate 2,4-cyclodiphosphate a sulfurated [sulfur carrier] SAM protein] N -octanoyl-L-lysine acyl-sn-glycerol halocarboxylate diphosphate protoheme in 16S rRNA acetamide dienoyl-CoA trehalose 6- phosphate N- biosynthesis I CTP BN1701_RS18480 α fluoroacetate and glycerol 3-phosphate 16S rRNA DNA cytosine amidase: NADPH-dependent ATP- phosphate acetyltransferase deoxy- -D-glucopyranose BN1701_RS29965 flavodoxin- citrate synthase 2: trehalose- a (1->4)- flavodoxin- a CDP-diacylglycerol purine nucleotides degradation II (aerobic) dUTP diphosphatase: dut (cytidine(1402)-2'-O) methyltransferase: 2,4-dienoyl- dependent dependent fluorothreonine biosynthesis chloramphenicol HAD family BN1701_RS03505 phosphatase: α-D-glucan GlmU: glmU UDP-α-D-glucose dependent CDP-diacylglycerol--serine nucleotide phosphatidate protoheme IX cholesterol esterase: -methyltransferase: BN1701_RS00845 CoA reductase: BN1701_RS29495 RNA helicase a (2E)-tetradec-2-enoyl-[acp] phosphotransferase [+ 2 isozymes] UDP-N-acetyl- (E)-4-hydroxy- (E)-4-hydroxy- hydrolase: farnesyltransferase: BN1701_RS17325 rsmI BN1701_RS29780 HrpA: hrpA otsB 1,4-alpha- fluoride O-phosphatidyltransferase: pyrophosphohydrolase: lipoyl synthase: lipA cytidylyltransferase: a 2'-O- [+ 3 isozymes] (2S,3S)-2- α α α-D-glucosamine dTDP-4-dehydro- 3-methylbut- 3-methylbut- CPT: cpt BN1701_RS01205 BN1701_RS06365 a 5-methylcytosine (indol-3-yl)acetate a (2E)-2- , '-trehalose glucan β enoyl-ACP pssA AMP BN1701_RS27280 BN1701_RS16835 methylcytidine 1402 methylcitrate an unwound RNA α -L-rhamnose 2-enyl- 2-enyl- SAM-dependent stearate biosynthesis a 3-sn-phosphatidyl- dUTP dUMP [+ 6 isozymes] in DNA enoyl-CoA 6- -mycolate branching reductase in 16S rRNA dTDP-4- diphosphate diphosphate chlorinase/fluorinase: II (bacteria and plants) L-serine CMP a 1-palmitoyl-2- protein FabI: fabI bifunctional a [pyruvate dehydrogenase lanosterol oleate dehydrorhamnose synthase: ispG synthase: ispG BN1701_RS25385 phosphatidylserine 5'-deoxyadenosine acyl-sn-glycero-3- a CDP-2,3,4-saturated- ferroheme o GlgB: glgB metallophosphatase/ met E2 protein] N 6 -lipoyl-L-lysine an unsulfurated [sulfur carrier] a (2R)-2- reductase: rfbD (E)-4-hydroxy-3- (E)-4-hydroxy-3- a palmitoyl-[acp] decarboxylase: 5-hydroxy-CTP 5-hydroxy-CMP phosphocholine diacylglycerol a halide anion a myristoyl-[acp] 5'-nucleotidase: hydroxy fatty acid methylbut-2-en- methylbut-2-en- 5'-deoxy-5'-fluoroadenosine β-ketoacyl- BN1701_RS29120 a GlgE-glycogen dTDP-β-L-rhamnose 1-yl diphosphate β BN1701_RS14085 IMP 1-yl diphosphate purine-nucleoside -ketoacyl- ACP synthase: an L-1- 3 (8S,9S,10S)- ACP synthase: BN1701_RS15155 phosphatidylethanolamine XLXG xyloglucan an N -methyladenine a dietary all- a cytidine 1402 phosphorylase: a 3-oxooctadecanoyl- adenosine GMP a 5-L-glutamyl- a sialyloligosaccharide an organic hydroperoxide N-ethylmaleimide an aliphatic amine 8,10-dimethyl- an aryl sulfate crotonyl-CoA BN1701_RS15155 an amino acid oligosaccharide in DNA trans-retinyl ester in 16S rRNA gly BN1701_RS22370 [acp] IMP dehydrogenase: pseudouridine [peptide] alkene reductase: 1-octalin peroxiredoxin: 16S rRNA primary-amine crotonyl-CoA 4-hydroxy- 4-hydroxy- 5-fluoro-5-deoxy-D- adenosine guaB degradation BN1701_RS10285 sulfatase: glycine a 3-oxohexadecanoyl-[acp] 3-oxoacyl- bifunctional BN1701_RS32750 (cytosine(1402)-N(4) oxidase: geosmin synthase: carboxylase/ 3-methylbut- ribose 1-phosphate deaminase: add exo-alpha-sialidase: beta-glucosidase: DNA-3- BN1701_RS00400 oxidase 3-methylbut- [acyl-carrier- metallophosphatase/ triacylglycerol lipase: thioredoxin- )-methyltransferase alkene reductase: BN1701_RS05110 reductase: BN1701_RS07760 BN1701_RS13745 methyladenine BN1701_RS13295 2-enyl 2-enyl 3-oxoacyl-[acyl- protein] adenosine deaminase: 5'-nucleotidase: pseudouridine gamma- BN1701_RS30015 RsmH: rsmH ccrA ThiO: thiO XMP dependent thiol an N 4 - BN1701_RS13635 diphosphate diphosphate Aromatic Compound Degradation glutamyltransferase: ggt exo-alpha-sialidase: beta-glucosidase: glycosylase I: an aldehyde a phenol (2S)- carrier-protein] reductase: BN1701_RS22515 BN1701_RS14085 peroxidase: bcp 1402 (-)-geosmin glyoxylate BN1701_RS08365 BN1701_RS17820 methylcytidine N-ethylsuccinimide reductase: 4-hydroxy- reductase: BN1701_RS31220 ethylmalonyl-CoA 4-hydroxy- 5-fluoro-5-deoxy-D- reductase: fabG fabG sphingomyelin metabolism bifunctional an alcohol ispH pseudouridine in 16S rRNA 3-methylbut- ispH 3-methylbut- a (3R)-3- inosine guanosine superpathway of an α-(5-L- all-trans-retinol a fatty acid ribulose 1-phosphate a (3R)-3- metallophosphatase/ 5'-phosphate catechol degradation to 2- 2-enyl 2-enyl hydroxyoctadecanoyl- an N-acyl- XXXG xyloglucan an apurinic site peptidoglycan biosynthesis I Cell Structure Biosynthesis 4-hydroxy-3- 4-hydroxy-3- hydroxyhexadecanoyl-[acp] 5'-nucleotidase: phenylethylamine hydroxypentadienoate II glutamyl)- a peptide N-acetylneuraminate an oligosaccharide D-galactopyranose 3-methyladenine lipid IV biosynthesis (E. coli) diphosphate [acp] purine-nucleoside purine-nucleoside oligosaccharide (meso-diaminopimelate containing) A diphosphate methylbut-2-enyl methylbut-2-enyl sphingosylphosphorylcholine BN1701_RS14085 pseudouridine- degradation amino acid within DNA reductase: diphosphate reductase: diphosphate phosphorylase: phosphorylase: UDP-N-acetyl- a (3R)-3- 5'-phosphate 2-phenylethylamine catechol ispH reductase: ispH reductase: sphingomyelin BN1701_RS22370 BN1701_RS22370 α-D-glucosamine hydroxytetradecanoyl- UDP-N-acetyl- xanthosine glycosidase: primary-amine catechol 2,3- (S)-2-oxo-4- fluoroacetaldehyde phosphodiesterase: UDP-N-acetyl-α-D-glucosamine undecaprenyl-diphospho-N a single XXLG xyloglucan p-nitrophenyl- an N 10 - (3S,5S)-3,5- α 4-hydroxy-3- BN1701_RS30830 4-hydroxy-3- BN1701_RS30830 BN1701_RS03975 a [protein] Ser/Thr rhodopin pyrazinamide UDP-N-acetylglucosamine [acp] -D-glucosamine a (2E)-octadec- oxidase: dioxygenase: -acetylmuramoyl-L-alanyl-γ- stranded DNA oligosaccharide β-D-galactoside hydroxy-4-carboxy- L-homoserine thr D-ala a (2E)-hexadec-2-enoyl-[acp] BN1701_RS32370 hypoxanthine guanine formyltetrahydrofolate diaminohexanoate 1-carboxyvinyltransferase: methylbut-2-enyl methylbut-2-enyl uracil BN1701_RS13295 BN1701_RS07550 D-glutamyl-L-lysyl- D-alanine 5-ureidoimidazoline serine/threonine L-erythro-3,5- fluoroacetaldehyde 2-enoyl-[acp] sphingosylphosphorylcholine 2-oxo-4-hydroxy- carotenoid amidase: murA acyl-ACP--UDP-N- diphosphate diphosphate purine-nucleoside phenylacetaldehyde protein kinase: cystathionine L-threonine 3- glycine catechol 2,3- undecaprenyldiphospho- beta-glucosidase: beta-glucosidase: 4-carboxy-5- diaminohexanoate 1,2-hydratase: BN1701_RS03505 α acetylglucosamine reductase: reductase: dehydrogenase: enoyl-ACP enoyl-ACP a sphingosine exodeoxyribonuclease gamma-lyase: dehydrogenase: oxidase UDP-N-acetyl- - phosphorylase: dioxygenase: muramoylpentapeptide beta-N- formyltetrahydrofolate BN1701_RS02925 dehydrogenase: BN1701_RS07825 BN1701_RS22465 reductase reductase ceramide phenylacetaldehyde VII: BN1701_RS30810 BN1701_RS13745 BN1701_RS13745 ureidoimidazoline BN1701_RS17395 [+ 2 isozymes] tdh ThiO: thiO D-glucosamine- O-acyltransferase: BN1701_RS30830 IPP BN1701_RS30830 IPP BN1701_RS22370 BN1701_RS07555 deformylase: purU BN1701_RS06970 FabI: fabI FabI: fabI dehydrogenase: acetylglucosaminyltransferase: BN1701_RS30820 beta-glucosidase: beta-glucosidase: decarboxylase: uraD [+ 12 isozymes] pyrazine-2- enolpyruvate BN1701_RS27455 4-fluorothreonine HMS a [protein] (L-serine/L- (S)-5-amino-3- all-trans-lycopene BN1701_RS22465 murG 2-oxobutanoate carboxylate aminoacetone pyruvate BN1701_RS17820 BN1701_RS17820 (S)-(+)-allantoin threonine) phosphate oxohexanoate UDP-N- fluoroacetate a palmitoyl-[acp] a stearoyl-[acp] xanthine UDP-3-O-[(3R)-3- isopentenyl- isopentenyl- 2-hydroxymuconate acetylmuramate phenylacetate ditrans,octacis-undecaprenyldiphospho- UDP a ribonucleoside a single-stranded formate a tetrahydrofolate hydroxymyristoyl]-N- diphosphate diphosphate purine ribonucleosides degradation 6-semialdehyde XXXG xyloglucan dehydrogenase: N-acetyl-(N-acetylglucosaminyl)muramoyl- 5'-monophosphate oligodeoxyribonucleotide D-galactopyranose D-galactopyranose acetyl-α-D-glucosamine phenylacetate- oligosaccharide 4-nitrophenol BN1701_RS24360 Delta- Delta- dehydrogenase: L-alanyl-γ-D-glutamyl-L-lysyl-D-alanine -CoA ligase: ala UDP-N-acetyl- isomerase: idi isomerase: idi BN1701_RS07620 α adenosine BN1701_RS32400 (2Z,4E)-2- -D-muramate palmitate stearate urate α undecaprenyl-diphospho-N-acetylmuramoyl-L- XLLG xyloglucan 6-O-cis-keto- UDP-3-O-(3- hydroxyhexa- UDP-N-acetyl- -D-glucosamine a proteinogenic 3,4-dihydroxyphenylacetyl- 4-fumaryl- β sn-glycerol 7,8-dihydro- a glycogen DMAPP alanyl-γ-D-glutamyl-L-lysyl- D-alanyl-D-alanine glutathione hydantoin NaMN L- -lysine (E)-2-hexenol mycolyl-trehalose DMAPP phenylacetyl-CoA 2,4-dienedioate oligosaccharide CoA acetoacetate 3-phosphate 8-oxoguanine UDP-N- glu hydroxymyristoyl) long-chain fatty long-chain fatty adenosine deaminase: add amino acid 6-phosphate glycogen α bifunctional lysine 5,6- zinc-binding alcohol 8-oxoguanine acetylmuramate-- - -D-glucosamine acid--CoA ligase: acid--CoA ligase: adenosine deaminase: phenylacetate- undecaprenyldiphospho- dihydropyrimidinase: L-glyceraldehyde trehalose- debranching metallophosphatase/ aminomutase dehydrogenase: deaminase: L-alanine ligase: UDP-3-O-(3- BN1701_RS29690 BN1701_RS29690 BN1701_RS22515 CoA oxygenase/ muramoylpentapeptide beta-N- beta-glucosidase: hydroxyphenylacetyl- hydA 3-phosphate phosphatase: protein glutamate racemase: fumarylacetoacetase: 5'-nucleotidase: subunit alpha: BN1701_RS00420 BN1701_RS04695 BN1701_RS15995 hydroxymyristoyl) acetylglucosaminyltransferase: BN1701_RS13745 CoA thioesterase reductase: mgrA otsB BN1701_RS33540 [+ 10 isozymes] [+ 10 isozymes] reductase: paaK (3E)-2-oxohex- gamma- fahA BN1701_RS14085 BN1701_RS06980 GlgX: glgX glucosamine N- murG beta-glucosidase: PaaI: paaI β L-glyceraldehyde xanthosine adenosine inosine guanosine paaJ paaC 3-enedioate glutamyltransferase: ggt N-carbamoylglycine -D- (3S,5S)-3,5- (E)-2-hexenal urate trehalose-cis-keto- a maltodextrin UDP-N-acetyl- acyltransferase: palmitoyl-CoA stearoyl-CoA BN1701_RS17820 3-phosphate paaB paaA 2-oxo-3- ribosylnicotinate diaminohexanoate mono-mycolate α-D-muramoyl- D-glt BN1701_RS27455 2-(1,2-epoxy-1,2- hexenedioate ditrans,octacis-undecaprenyldiphospho-N- (3,4- L-alanine UDP-2-N,3-O-bis[(3R)- UDP an α-(γ-L-glutamyl) coenzyme A acetoacetate fumarate purine-nucleoside purine-nucleoside purine-nucleoside purine-nucleoside dihydrophenyl) decarboxylase: acetyl-(N-acetyl-β-D-glucosaminyl)muramoyl-L- L-cysteinylglycine XXXG xyloglucan dihydroxyphenyl) 3-hydroxytetradecanoyl]- peptidoglycan maturation (meso-diaminopimelate containing) -L-amino acid D-galactopyranose phosphorylase: phosphorylase: phosphorylase: phosphorylase: acetyl-CoA alanyl-γ-D-glutamyl-L-lysyl-D-alanyl-D-alanine oligosaccharide acetate UDP-N- α-D-glucosamine BN1701_RS07610 lipid II (meso BN1701_RS22370 BN1701_RS22370 BN1701_RS22370 BN1701_RS22370 (2Z)-2- acetylmuramoyl- diaminopimelate containing) Metabolic Regulator Biosynthesis hydroxypenta- L-alanine--D- a 1,2-diacyl- adenine 1518 / (2R,3S)-3- 2,4-dienoate dethiobiotin a sulfurated glutathione CDP-choline succinate a ribonucleoside oxaloacetate cerotoyl-CoA androstenedione butan-1-ol 15-cis-phytoene α SAM 1519 cys glutamate ligase: -D-ribose-1-phosphate 2-oxepin-2(3H)- [sulfur carrier] hypoglycin A sn-glycerol adenine in 16S rRNA 5'-monophosphate isopropylmalate lipid X mannosylglucosylglycerate ylideneacetyl-CoA 16S rRNA propionyl-CoA BN1701_RS16010 ppGpp metabolism glucosylglycerate UTP and CTP dephosphorylation I bifunctional 3-oxosteroid 1- 3-isopropylmalate zinc-binding alcohol phytoene a nascent peptidoglycan biosynthesis I trehalose biosynthesis II (adenine(1518)-N(6)/ citrate synthase: carboxylase cystathionine biosynthesis I oxepin-CoA chloramphenicol ADP-forming metallophosphatase/ dehydrogenase: dehydrogenase: dehydrogenase: desaturase: UDP-N-acetyl- poly-gamma- with (L-alanyl-γ-D-glutamyl- biotin adenine(1519)-N(6))- BN1701_RS29535 subunit beta: gamma-lyase: meso- 3-phospho- D-glucopyranose UTP hydrolase: phosphotransferase succinate--CoA 5'-nucleotidase: BN1701_RS21355 BN1701_RS18125 BN1701_RS00420 crtI α-D-muramoyl-L- glutamate meso-2,6-diaminopimeloyl-D- pppGpp 3-phospho- α synthase gamma- dimethyltransferase BN1701_RS03100 BN1701_RS17395 diaminopimelate D-glycerate α ADP- -D-glucose 6-phosphate paaZ CPT: cpt ligase: sucD sucC BN1701_RS14085 1,2-dihydroxypropane- androsta-1,4- 4-methyl-2- 9,15,9'-tri-cis alanyl-D-glutamate synthase alanyl-D-alanine) pentapeptide D-glycerate GDP- -D-glucose D-ribose 5-phosphate thymine degradation glutamyltransferase: ggt 2-carboxycerotoyl- 1-butanal 3-oxo-5,6- catechol degradation to BioB: bioB 6 RsmA: rsmA1518 pyruvate ζ PgsB: pgsB glucosyl-3- bifunctional (p)ppGpp CTP synthase: N -dimethyladenine a ribonucleoside 1,2,3-tricarboxylate diene-3,17-dione oxopentanoate - -carotene didehydrosuberyl- 2-hydroxypentadienoate I CoA phosphoglycerate synthetase/guanosine- trehalose-6- BN1701_RS14015 thymine /N 6 -dimethyladenine 1519 UDP-N- lipid A disaccharide D-alanyl-D-alanine penicillin-binding guanosine 3'- glucosyl-3- CoA semialdehyde CMP synthase: 3',5'-bis(diphosphate) 3'- phosphate synthase: biotin 5'-deoxyadenosine an unsulfurated a phosphatidylcholine ADP succinyl-CoA in 16S rRNA acetylmuramoyl- (E. coli) carboxypeptidase/ protein 2: diphosphate 5'- phosphoglycerate UDP 3-oxo-5,6- catechol met hypoglycin B L-cysteinylglycine phosphate BN1701_RS31145 pyrophosphohydrolase: BN1701_RS28875 CTP [sulfur carrier] L-alanyl-D- D-alanyl-D-alanine- BN1701_RS26735 a mature peptidoglycan with triphosphate 3'- synthase: dehydrosuberyl- D-ala 2-O-(α-D- BN1701_RS14525 5,6-dihydrothymine glutamate--2, 6- endopeptidase: dacB (L-alanyl-γ-D-glutamyl-meso- diphosphatase: BN1701_RS31145 CoA semialdehyde catechol 2,3- D-alanyl-D-alanine glucopyranosyl) α,α-trehalose diaminopimelate 2,6-diaminopimeloyl-D-alanyl- BN1701_RS14525 dihydropyrimidinase: dehydrogenase: dioxygenase: D-alanine--D- carboxypeptidase/ α 6-phosphate a 3,5,7,9,11,13,15- (1R,6R)-6-hydroxy-2- a double-stranded lipid IV (E. coli) a nascent peptidoglycan -3-phospho- GDP- -D- 2-O-(α-D- UMP hydA BN1701_RS07550 UDP-N-acetyl-α-D-muramoyl- a [mycoredoxin]- mycothiol- + a secondary ligase: A D-alanyl-D-alanine- D-alanine) pentapeptide CDP paaZ D-alanyl-D-alanine NAD(P)H a plastoquinone H coenzyme A succinylcyclohexa-2,4- rhodopin D-glycerate butan-1-ol L-dopa ethanol alanine ligase: γ D-glycerate mannose L-alanyl-γ-D-glutamyl-L-lysine L-cysteine arsenate conjugate hepta-oxo- oligonucleotide alcohol BN1701_RS16025 with (L-alanyl- -D-glutamyl- endopeptidase: dacB glucopyranosyl) trehalose- bifunctional 3-(carbamoylamino)- 3-oxo-5,6- catechol 2,3- diene-1-carboxylate BN1701_RS17360 GTP ppGpp hexadecanoyl-[PKS-acp] carotenoid D-glycerate zinc-binding alcohol zinc-binding alcohol catalase/ meso-2,6-diaminopimeloyl- -3-phospho- trehalose biosynthesis I phosphatase: metallophosphatase/ 2-methylpropanoate didehydrosuberyl- dioxygenase: aldo/keto reductase: o-succinylbenzoate oligoribonuclease: 4,5-DOPA D-alanine--D- 1,2-hydratase: dehydrogenase: dehydrogenase: dehydrogenase: peroxidase UDP-N-acetyl- D-alanine) tetrapeptide a nascent peptidoglycan D-glycerate otsB 5'-nucleotidase: CoA BN1701_RS07555 UDP-N-acetylmuramoyl- NAD(P)H-quinone BN1701_RS04310 synthase: menC orn dioxygenase β mycoredoxin: CoA pyrophosphatase: α alanine ligase: D-glucopyranose -ureidopropionase: dehydrogenase: BN1701_RS07825 BN1701_RS03345 BN1701_RS00420 BN1701_RS00420 HPI: katG -D-muramoyl- with D,D cross-links (meso- α α CMP BN1701_RS14085 tripeptide--D-alanyl- BN1701_RS01980 BN1701_RS28210 [+ 8 isozymes] [+ 2 isozymes] extradiol: ygiD BN1701_RS26530 2-[2-O-(α-D- nucleoside- UDP-α-D-glucose , -trehalose BN1701_RS04460 HMS 1,1'-dihydroxy-1,1',2,2'- a nucleoside 5'- L-alanyl-γ-D- L,D-transpeptidase: L,D-transpeptidase: diaminopimelate containing) 6-phosphate D- alanine ligase: BN1701_RS22240 9-hydroxy-3,5,7,11,13,15- hydroxypyruvate a ketone 1-butanal acetaldehyde GDP bifunctional uridine 2-succinylbenzoate 4,5-seco-dopa BN1701_RS09345 BN1701_RS09345 mannopyranosyl) diphosphate α BN1701_RS16020 hexaoxohexadecanoyl- tetrahydrolycopene monophosphate glutamyl-meso-2,6- D-alanyl-D-alanine bifunctional (p)ppGpp 2-O-( -D- metallophosphatase/ (R)-3-amino-2- L,D-transpeptidase: a nascent peptidoglycan with L,D-transpeptidase: a mature peptidoglycan -(1->2)-α-D- kinase: ndk pyrophosphokinase: trehalose-6- trans-2,3- a [mycoredoxin] [PKS-acp] diaminopimelate synthetase/guanosine- glucopyranosyl) 5'-nucleotidase: methylpropanoate (L-alanyl-γ-D-glutamyl-meso- with (L-alanyl-γ-D-glutamyl- glucopyranosyl]- BN1701_RS14525 dehydroadipyl-coA arsenite mycothiolyl-S-S- a plastoquinol + 3',5'-ADP 4'-phosphopantetheine BN1701_RS34895 BN1701_RS34895 -D-glycerate phosphate synthase: UDP-N-acetyl-α-D-muramoyl-L-alanyl- NAD(P) 2,6-diaminopimelate) tripeptide meso-2,6-diaminopimeloyl- a mature peptidoglycan 3-phospho- 3',5'-bis(diphosphate) 3'- BN1701_RS14085 enoyl-CoA L-cysteine disulfide UDP-N- BN1701_RS28875 (2Z)-2- γ-D-glutamyl-L-lysyl-D-alanyl-D-alanine a nascent peptidoglycan a nascent peptidoglycan with D,D cross-links (meso- D-glycerate pyrophosphohydrolase: trehalose biosynthesis IV hydratase: acetylmuramoyl- D-alanine) tetrapeptide cytidine hydroxypenta- formate with L,D cross links (meso- with (L-alanyl-γ-D-glutamyl- diaminopimelate containing) BN1701_RS14525 α α BN1701_RS23745 tripeptide--D-alanyl- , -trehalose 2,4-dienoate diaminopimelate containing) meso-2,6-diaminopimeloyl- GDP α-maltose (3S)- an [HPr]- phosphoenol a 2-deoxy-D- D-threo-7,8- 2-hydroxy-5- γ-glutamyl- D- alanine ligase: a mature peptidoglycan with 6-phosphate a nucleobase phylloquinone H + γ maltose alpha-D- hydroxyadipyl- NAD(P)H carboxymethylmuconate protoporphyrinogen IX citrate an acyl phosphate D-glycerate pyruvate -carotene MeOH BN1701_RS16020 γ glycine) tetrapeptide α L-histidine pyruvate ribosyl-base dihydroneopterin isopropylamide (L-alanyl- -D-glutamyl-meso- 2-[2-O-( -D- trehalose- Carboxylate Degradation semialdehyde glucosyltransferase: treS CoA 5-carboxymethyl-2- D-glycerate ferredoxin: pyruvate carotenoid catalase/ 2,6-diaminopimelate) tripeptide mannopyranosyl) phosphatase: protoporphyrinogen aconitate hydratase: acylphosphatase: UDP-N-acetyl- a mature peptidoglycan α maltose alpha-D- hydroxymuconate dehydrogenase: BN1701_RS34040 carboxylase: 1,2-hydratase: peroxidase -(1->2)- -D- otsB propanoyl CoA phosphoenolpyruvate- nucleoside 2- NAD(P)H-quinone dihydroneopterin oxidase: hemG BN1701_RS05710 BN1701_RS17050 α-D-muramoyl- with L,D cross-links (meso- glucosyltransferase: treS pyruvate decarboxylation to acetyl CoA I acetate semialdehyde BN1701_RS03345 [+ 4 isozymes] BN1701_RS17180 BN1701_RS07825 HPI: katG a mature peptidoglycan glucopyranosyl]- degradation I -protein deoxyribosyltransferase: dehydrogenase: γ α,α-trehalose α,α-trehalose aldolase: folB N-(γ-L-glutamyl) 1'-hydroxy- L-alanyl- -D- diaminopimelate containing) with (L-alanyl-γ-D-glutamyl- D-glycerate conversion phosphotransferase: ptsP BN1701_RS01190 BN1701_RS22240 dehydrogenase: hpaE D-threo-isocitrate hydroxypyruvate oxaloacetate formaldehyde 3-oxoadipyl-CoA 5-carboxymethyl-2- protoporphyrin IX a carboxylate glutamyl-meso-2,6- di-trans,octa-cis meso-2,6-diaminopimeloyl- a [pyruvate dehydrogenase pyruvate to acetyl-CoA -L-alaninol γ-carotene propanoyl-CoA 6 hydroxymuconate diaminopimeloyl- -undecaprenyl E2 protein] N -lipoyl-L-lysine pyruvate glycine) tetrapeptide acyl-CoA dehydrogenase acetate an [HPr protein]- a 2-deoxy-D- 6-(hydroxymethyl) glycolaldehyde D-alanyl-D-alanine phosphate π pyruvate a nucleobase NAD(P) + phylloquinol carboxylase (acetyl-transferring) acetate--CoA N -phospho- ribosyl-base -7,8-dihydropterin subunit beta: dihydrolipoyl , homodimeric ligase: acs L-histidine phospho-N- BN1701_RS33260 dehydrogenase: lpdA type: aceE acetate--CoA succinyl-CoA acetylmuramoyl- [+ 4 isozymes] dihydrolipoyl pyruvate ligase: acs an [amino-group carrier protein]- pentapeptide- L-histidine biosynthesis Amino Acid Biosynthesis (S)-methylmalonyl- a 1-arachidonoyl- D-cellobiose 1-aminocyclopropane- (2R)-phospho- 4-hydroxy-3- (6E)-8- cholest-4- phosphoenol L-arginine biosynthesis I (via L-ornithine) L-lysine biosynthesis I L-arginine biosynthesis II (acetyl cycle) L-proline biosynthesis dehydrogenase: lpdA dehydrogenase acetyl-CoA a proteinogenic leukotriene-C4 CDP-choline C-terminal-γ-(L-glutamate 5- 4-nitrocatecholsulfate a primary amine acetamide transferase: L-tryptophan biosynthesis CoA 2-acyl-sn-glycerol 6'-phosphate 1-carboxylate 3-sulfolactate octaprenylbenzoate oxogeraniol en-3-one pyruvate I (from L-glutamate) (acetyl-transferring) amino acid semialdehyde-2-yl)-L-glutamate BN1701_RS16015 methylmalonyl- N-acetyl-gamma- 1-aminocyclopropane- 2-phosphosulfolactate UbiD family primary-amine zinc-binding alcohol 3-oxosteroid 1- amidase: PRPP N-acetylglutamyl- E1 component C1 Compound Utilization and Assimilation sulfatase: pyruvate glu asp CoA a [pyruvate dehydrogenase chloramphenicol 6-phospho-beta- glutamyl-phosphate 1-carboxylate phosphatase: decarboxylase: oxidase: dehydrogenase: dehydrogenase: BN1701_RS03505 bifunctional phosphate chorismate gln a [pyruvate dehydrogenase E2 subunit alpha: pdhA BN1701_RS00400 kinase: pyk undecaprenyldiphospho- ATP glu epimerase: mce E2 protein] N 6 -S- phosphotransferase glucosidase: reductase: deaminase: BN1701_RS01875 BN1701_RS14745 BN1701_RS13295 BN1701_RS00420 BN1701_RS21355 [+ 2 isozymes] aspartate kinase: 6 gamma- N-acetylmuramoyl-L- phosphoribosyltransferase: glutamate N- protein] N -dihydrolipoyl-L-lysine formaldehyde CPT: cpt an [amino-group carrierBN1701_RS14130 protein]- BN1701_RS10135 (6E)-8- cholesta-1,4- bifunctional BN1701_RS28025 glutamate 5-kinase: (R)-methylmalonyl- acetyldihydrolipoyl-L-lysine formaldehyde glutamyltransferase: ggt BN1701_RS07140 (2R)-3-sulfolactate 4-nitrocatechol 2-octaprenylphenol an aldehyde acetate pyruvate γ acetyltransferase/ lipoate γ oxogeranial dien-3-one alanyl- -D-glutamyl-meso BN1701_RS06730 glutamate N- anthranilate synthase BN1701_RS02360 CoA oxidation V oxidation III C-terminal- -(5-phospho- 2-oxobutanoate amino-acid γ-L-glutamyl acetyltransferase: -2,6-diaminopimeloyl- acetyltransferase/ superpathway of branched chain amino acid biosynthesis L-aspartyl-4-phosphate N-acetyl-gamma- (bacillithiol-dependent) (mycothiol-dependent) L-glutamyl)-L-glutamate β component I: methylmalonyl- a 1-arachidonoyl-2-acyl-sn CMP D-glucopyranose D-alanyl-D-alanine 1-(5-phospho- -D-ribosyl)-ATP acetyltransferase 5-phosphate aceE an α-(γ-L-glutamyl) D-glucopyranose amino-acid glutamyl-phosphate BN1701_RS17765 formaldehyde undecaprenyldiphospho- ArgJ: argJ CoA mutase formaldehyde leukotriene-D4 -glycero-3-phosphocholine 6-phosphate phosphoribosyl-ATP acetyltransferase pyruvate aspartate- reductase: gamma-glutamyl- -L-amino acid muramoylpentapeptide beta-N- thr small subunit: D-gluconate diphosphatase: ArgJ: argJ semialdehyde amino-acid N- acetylglutamate BN1701_RS14130 phosphate anthranilate PRPP BN1701_RS22345 degradation acetylglucosaminyltransferase: acetolactate dehydrogenase: acetyltransferase: reductase: S-(hydroxymethyl) BN1701_RS06725 amino-acid N- threonine/serine kinase: argB methylmalonyl- S-(hydroxymethyl) 5-amino-4- an [amino-group carrier protein]-C- (6E)-8- murG synthase BN1701_RS28030 BN1701_RS16210 gln N-acetyl-L-glutamate BN1701_RS27415 acetyl-CoA mycothiol hydrogen selenide PRPP fumarate a nucleoside chlorobactene a primary alcohol an aldehyde homogentisate (S)-NADPHX (R)-lactate glyoxylate acetyltransferase: dehydratase: glu N-acetyl-L-glutamate D-gluconate bacillithiol O-acetyl-L-serine asp γ lipid II (meso 1-(5-phospho-β-D-ribosyl)-AMP large subunit: 5-semialdehyde CoA imidazolecarboxyamide terminal- -(L-ornithyl)-L-glutamate triphosphate hydroxygeranial BN1701_RS16210 L-aspartate 4- anthranilate L-glutamate-5- gluconokinase: S-(hydroxymethyl) S-(hydroxymethyl) diaminopimelate BN1701_RS02990 BN1701_RS10660 mutase: scpA acetylornithine nucleotide carotenoid zinc-binding alcohol zinc-binding alcohol zinc-binding alcohol homogentisate NAD(P)H-hydrate D-2-hydroxyacid malate semialdehyde glutamine- acetylornithine phosphoribosyltransferase: trpD semialdehyde BN1701_RS07090 mycothiol mycothiol containing) phosphoribosyl-AMP N-acetyl-L- [+ 2 isozymes] D-gluconate adenine transaminase: pyrophosphohydrolase: 1,2-hydratase: dehydrogenase: dehydrogenase: dehydrogenase: 1,2-dioxygenase: dehydratase: dehydrogenase: synthase acetolactate hydrolyzing bifunctional transaminase: succinyl-CoA dehydrogenase: dehydrogenase: cyclohydrolase: hisI glutamate (2Z)-2-aminobut- 4-hydroxy- 6-phosphate cysteine synthase: phosphoribosyltransferase: L-aspartate oxidase: BN1701_RS14115 BN1701_RS27280 BN1701_RS07825 BN1701_RS00420 BN1701_RS00420 BN1701_RS00420 BN1701_RS27150 BN1701_RS23095 BN1701_RS21405 A: aceB synthase: ilvN carbamoyl- glutamate N- BN1701_RS14115 BN1701_RS26850 BN1701_RS26850 an [amino-group carrier protein]- 1-(5-phospho-β-D-ribosyl)- 2-enoate tetrahydrodipicolinate N-(5-phosphoribosyl)-anthranilate BN1701_RS33510 BN1701_RS14530 BN1701_RS17965 a nucleoside 5'- (6E)-8- 4-maleyl- acetylglutamate BN1701_RS18160 phosphate acetyltransferase/ C-terminal-γ-(L-glutamate 5- 1-hydroxychlorobactene an aldehyde an alcohol NADPH pyruvate (S)-malate 5-[(5-phosphoribosylamino) synthase: dapA S-formylbacillithiol monophosphate oxogeranial acetoacetate kinase: argB synthase: amino-acid N-(5'-phosphoribosyl) (S)-1-pyrroline- S-formylmycothiol semialdehyde-2-yl)-L-glutamate methylideneamino]imidazole- (S)-2-acetolactate 4-hydroxy- carB carA acetyltransferase anthranilate isomerase: 5-carboxylate Secondary Metabolite Degradation succinate 4-carboxamide N-acetylglutamyl- tetrahydrodipicolinate acetate L-selenocysteine AICAR 2-iminosuccinate ketol-acid ArgJ: argJ BN1701_RS33320 pyrroline-5- bifunctional 1-(5- phosphate 2-iminobutanoate synthase: dapA carbamoyl phosphate L-ornithine L-isoleucine superpathway of L-cysteine reductoisomerase: (2S,4S)-4- [+ 2 isozymes] carboxylate anhydromuropeptides recycling I phosphoribosyl)-5-((5- N-acetyl-gamma- N-acetyl-L-ornithine biosynthesis IV biosynthesis (mammalian) ilvC hydroxy-2,3,4,5- 1-(2-carboxyphenylamino)-1- reductase: formate formate phosphoribosylamino) glutamyl-phosphate 6 DNA combined with a 2-O-(α-D-mannosyl)-1- UDP-N-acetyl- (2R)-2,3- tetrahydrodipicolinate deoxy-D-ribulose 5-phosphate proC GlcNAc-1,6- + a [histone]-N - a monocarboxylic (2R,3S)-3- uridine methylideneamino)imidazole- NAD glycyl-glycine glutathione a folate 1-hydroxyneurosporene oxaloacetate α phytol reductase: dihydroxy-3- propanoate met anhMurNAc- acetyl-L-lysine exogenous DNA to form phosphatidyl-1D-myo-inositol acid amide -D-glucosamine isopropylmalate 4- carboxamide isomerase/ 4-hydroxy- indole-3-glycerol- phosphatidylinositol UDP-N- uridine kinase: BN1701_RS14130 methylbutanoate long-chain fatty L-Ala-γ-D-Glu- a recombinational junctionHolliday junction dihydrofolate reductase: carotenoid phosphoenolpyruvate amidase: 3-isopropylmalate zinc-binding alcohol phosphoribosylanthranilate 2-oxobutanoate tetrahydrodipicolinate phosphate synthase: pro mannoside acetylglucosamine BN1701_RS14405 N-acetyl-L- dihydroxy-acid acid--CoA ligase: methionine DAP-D-Ala resolvase RuvX: ruvX BN1701_RS20535 1,2-hydratase: carboxykinase (GTP) BN1701_RS03505 dehydratase: dehydrogenase: reductase: ornithine BN1701_RS33325 NAD-dependent acyltransferase: uridine kinase: isomerase PriA: priA glutamate 5- dehydratase: BN1701_RS29690 adenosyltransferase: gamma- dihydrofolate reductase: 2-epimerase (non- acetolactate BN1701_RS16420 carbamoyltransferase: deacylase: crossover junction BN1701_RS07825 : BN1701_RS26105 [+ 2 isozymes] leuD leuC BN1701_RS00420 semialdehyde [+ 10 isozymes] [+ 2 isozymes] BN1701_RS14250 glutamyltransferase: ggt BN1701_RS14625 BN1701_RS32835 hydrolyzing): wecB BN1701_RS15875 phosphoribulosylformimino- ilvD synthase BN1701_RS16120 endodeoxyribonuclease a 2-O-(6-O-acyl-α-D-mannosyl)- all-trans phosphoenol UDP-N-acetyl-α- (2S)-2- acetylornithine (S)-2,3,4,5- BN1701_RS10680 propanoyl-CoA a monocarboxylate phytenal UMP AICAR-phosphate 3-methyl-2- (1S,2R)-1-C-(indol-3- methionine a 7,8-dihydrofolate neurosporene pyruvate D-mannosamine isopropylmalate hydrogencarbonate transaminase: large subunit: tetrahydrodipicolinate ornithine resolution of recombinationalRuvC: ruvC 1-phosphatidyl-1D-myo-inositol oxobutanoate yl)glycerol 3-phosphate adenosyltransferase: N-acetyl-β-D- L-alanyl-γ-D- BN1701_RS14115 BN1701_RS02990 2,3,4,5- carbamoyltransferase: 2-oxoacid:ferredoxin superpathway of L-serine 2''-O-acetyl- γ-L-glutamyl- junction formation imidazole glycerol glutamine- BN1701_RS33330 glucosamine-1,6- glutamyl-meso-2,6- L-cysteinylglycine acetolactate tetrahydropyridine- argF oxidoreductase tryptophan synthase and glycine biosynthesis I ADP-ribose a [histone]-L-lysine nicotinamide glycylglycine of two intact strands hydrolyzing N-acetyl-L- anhydro-N-acetyl- diaminopimeloyl- phosphate synthase 2-isopropylmalate branched-chain synthase: ilvN 2,6-dicarboxylate N- subunit beta: subunit alpha: trpA carbamoyl- ornithine SAM β-D-muramate D-alanine subunit HisH: hisH synthase: leuA amino acid BN1701_RS18160 succinyltransferase: BN1701_RS23755 [+ 2 isozymes] 3-phospho-D-glycerate phosphate phosphoglycerate glcNAc-1,6- imidazole glycerol aminotransferase: (S)-2-aceto-2- dapD ser a [protein]-N 6 - 6-[1-hydroxyethyl]-7- (3,4-dihydroxyphenyl) a single 3-(4- a uridine 55 adenosyl-cob(III) (2S)- cytidine indole NAD + D-glucopyranose phosphate synthase synthase: (2S)-2- BN1701_RS03250 2-oxobutanoate dehydrogenase: anhMurNAcaminidase: hydroxyphenyl) 1-hydroxyneurosporene a 3-oxosteroid hydroxybutanoate N-succinyl-2-amino- acetyl-L-lysine methyl-7,8-dihydropterin acetate stranded DNA in tRNA yrinate a,c-diamide ethylmalonyl-CoA uridine kinase: subunit HisF: hisF carB carA isopropylmalate BN1701_RS18130 BN1701_RS28290 L-alanyl-γ-D- pyruvate glucose 1- branched-chain ketol-acid 6-ketopimelate 2-amino-4-hydroxy-6- carotenoid tRNA cobyric acid 3-oxosteroid 1- methylmalonyl- BN1701_RS14405 acetolactate 3-phosphooxypyruvate 1,6-anhydro-N- 3,4-dihydroxyphenylacetate deoxyribonuclease carbamoyl 3-isopropylmalate amino acid reductoisomerase: L-citrulline tryptophan synthase glutamyl-meso- hydroxymethyldihydropteridine 4-hydroxyphenylpyruvate 1,2-hydratase: pseudouridine(55) synthase: dehydrogenase: dehydrogenase: CoA L-ornithine succinyldiaminopimelate synthase β NAD-dependent 2,3-dioxygenase: hpaD uridine kinase: phosphate dehydratase: SAH acetyl- -muramate diaminopimelate diphosphokinase: folK IV: BN1701_RS26300 dioxygenase: hppD BN1701_RS07825 BN1701_RS21155 BN1701_RS21355 epimerase: mce AICAR D-erythro-1-(imidazol-4- aminotransferase: ilvC transaminase: large subunit: subunit alpha: trpA phosphoserine deacylase: synthase TruB: truB BN1701_RS16715 BN1701_RS15875 leuD leuC argininosuccinate [1-(2-amino-7-methyl-4-oxo- 2-hydroxy-5- 55 yl)-glycerol 3-phosphate BN1701_RS08345 (R)-2,3-dihydroxy- BN1701_RS31090 BN1701_RS02990 [+ 2 isozymes] transaminase: BN1701_RS16120 1,1'-dihydroxy- a pseudouridine D-glucono- a 3-oxo- (2R)- Inorganic Nutrient Metabolism 7,8-dihydro-3H-pteridin- carboxymethylmuconate a 5'-phosphooligonucleotide homogentisate adenosylcobyrate ∆ 1 CMP ornithine synthase: adenosylhomocysteinase: BN1701_RS29455 neurosporene in tRNA 1,5-lactone -steroid ethylmalonyl-CoA imidazoleglycerol- 2-isopropylmaleate 3-methylpentanoate N-succinyl-L,L-2,6- BN1701_RS14100 acetolactate BN1701_RS21880 6-yl)]ethyl diphosphate semialdehyde phosphate carbamoyltransferase: dihydroxy-acid N-acetyl-D- 2''-O-acetyl- 3-isopropylmalate val diaminopimelate synthase: ilvN trp assimilatory urea cycle dehydratase BN1701_RS10680 dehydratase: O-phospho-L-serine muramate 6- assimilatory polyphosphate ADP-ribose nicotinamide a [protein]-L-lysine dehydratase: succinyl- L-arginino-succinate BN1701_RS18160 sulfate reduction IV HisB: hisB ornithine ilvD L-homocysteine ser phosphate sulfate reduction III metabolism leuD leuC diaminopimelate (S)-2-aceto-2- N-acetylmuramic carbamoyltransferase: (3S)-3-methyl-2- argininosuccinate phosphoserine arg 3-(imidazol-4-yl)-2- desuccinylase: hydroxybutanoate acid 6-phosphate sulfate long chain 4a-hydroxy-L- argF (2R,3S)-3- oxopentanoate lyase: argH phosphatase SerB: serB sulfate 3-methyl-2- 5,10-methylene- 25-hydroxycholest- (R)-3- (S)-2- dCTP oxopropyl phosphate BN1701_RS31115 2-aceto-2-hydroxy- cystathionine etherase: sulfate polyphosphate a double stranded DNA erythro-5,6,7,8- 3-demethylubiquinol-9 uroporphyrinogen-III 2-hydroxyisobutyramide D-glucopyranose D-glycerate isopropylmalate sulfate oxobutanoate tetrahydromethanopterin 4-en-3-one hydroxybutanoate hydroxyglutarate branched-chain butanoate beta-synthase: BN1701_RS28270 adenylyltransferase DNA topoisomerase 4 tetrahydrobiopterin histidinol-phosphate 3-isopropylmalate ser adenylyltransferase 3-demethylubiquinone- amidase: 3-oxosteroid 1- 3-hydroxybutyrate glucose 1- L-2- dCTP deaminase: amino acid L,L-diaminopimelate arg isomeroreductase: N-acetyl-D- subunit 2: 4a-hydroxytetrahydrobiopterin transaminase: asp L-citrulline dehydrogenase: L-cysteine biosynthesis V (mycobacteria) BN1701_RS30575 subunit 2: subunit A: BN1701_RS11540 uroporphyrinogen dehydrogenase: glycerate kinase: BN1701_RS25810 aminotransferase: BN1701_RS02620 3-methyl-2-oxobutanoate 9 3-O- BN1701_RS03505 dehydrogenase: dehydrogenase: hydroxyglutarate BN1701_RS17905 ilvC glucosamine BN1701_RS02620 RNA degradosome dehydratase: decarboxylase: hemE BN1701_RS03295 BN1701_RS18125 diaminopimelate L-arginine serine APS hydroxymethyltransferase: DNA topoisomerase (ATP- methyltransferase: ubiG [+ 2 isozymes] BN1701_RS21355 BN1701_RS24550 BN1701_RS21155 oxidase: lhgO BN1701_RS03250 (R)-2,3-dihydroxy- 6-phosphate APS polyphosphate BN1701_RS30905 dUTP histidinol-phosphate (2S)-2-isopropyl- epimerase: degradation I O-phospho- hydroxymethyltransferase: panB hydrolyzing) subunit B: gyrB 2-hydroxy-2- 25-hydroxycholesta- D-glucono- 2-phospho- argininosuccinate branched-chain 3-methylpentanoate L-cystathionine N-acetylglucosamine- ammonium kinase: (6R)-L-erythro-6,7- ubiquinol-9 coproporphyrinogen III acetoacetate 2-oxoglutarate transaminase: hisC 3-oxosuccinate BN1701_RS03720 (arginase pathway) a [CysO sulfur- L-serine BN1701_RS15490 a negatively supercoiled DNA methylpropanoate 1,4-dien-3-one 1,5-lactone D-glycerate synthase: amino acid 6-phosphate argininosuccinate phosphoadenylyl- BN1701_RS17415 dihydrobiopterin dihydroxy-acid carrier protein]- [+ 2 isozymes] BN1701_RS14100 arg L-homoserine cystathionine deacetylase: nagA lyase: argH glutamine- sulfate reductase: L-histidinol phosphate aminotransferase: meso-diaminopimelate thiocarboxylate dehydratase: ilvD CysO- gamma-lyase: BN1701_RS02625 2-dehydropantoate THMPT BN1701_RS08345 biosynthesis gly D-glucosamine L-arginino- hydrolyzing thiocarboxylate- BN1701_RS17395 PAPS L-ornithine long chain histidinol- L-arginino- (3S)-3-methyl-2- 6-phosphate succinate carbamoyl- 4-methyl-2- diaminopimelate dependent sulfite polyphosphate phosphatase: hisN succinate asp oxopentanoate phosphoglucosamine phosphoadenylyl- phosphate oxopentanoate ile decarboxylase: lysA L-ornithine cysteine synthase: cys synthase: 2,5-diamino-6-(5- trans,octacis-decaprenylphospho- 10 UTP CTP argininosuccinate diaminopimelate branched-chain mutase: sulfate reductase: argininosuccinate assimilatory sulfite 4a-hydroxy-N - 3-phenyl-2- dihydroxyacetone a chitodextrin D-ribofuranose branched-chain aspartate kinase: BN1701_RS33510 carB carA phospho-D-ribitylamino) β-D-arabinofuranose uroporphyrinogen-I 4-guanidinobutyramide (S)-NADHX L-asparagine histidinol amino acid BN1701_RS23125 BN1701_RS02625 synthase: reductase (NADPH) formyltetrahydrofolate oxopropanoate nucleotide lyase: argH amino acid decarboxylase: lysA ornithine- BN1701_RS28025 decaprenylphospho-beta- dCTP deaminase: biosynthesis I aminotransferase: adenylyltransferase/ L-tyrosine BN1701_RS14100 : BN1701_RS02635 pyrimidin-4(3H)-one 4a-hydroxytetrahydrobiopterin amidase: NAD(P)H-hydrate aminotransferase: -oxo-acid L-aspartyl- L-phenylalanine α-D-glucosamine carbamoyl bifunctional D-erythro-pentofuranosid- 4-hydroxyphenylpyruvate uroporphyrinogen pyrophosphohydrolase: dihydroxyacetone chitinase: ribokinase: histidinol BN1701_RS03250 sulfurtransferase biosynthesis I sulfite ornithine glyphosate dehydratase: BN1701_RS03505 dehydratase: BN1701_RS25810 arg BN1701_RS03250 lys transaminase: 4-phosphate a [CysO sulfur- biosynthesis I 1-phosphate phosphate diaminohydroxyphosphoribosylaminopyrimidine 2-ulose 2-reductase: dioxygenase: hppD decarboxylase: hemE BN1701_RS27280 kinase: dhaL dhaK BN1701_RS13175 BN1701_RS26435 dehydrogenase: hisD a [CysO sulfur-MoeZ: moeZ carbamoyltransferase: hydrogen sulfide degradation II BN1701_RS30905 [+ 2 isozymes] BN1701_RS23095 asp ammonia assimilation cycle III rocD branched-chain carrier protein]- octaheme sulfite deaminase/5-amino-6-(5-phosphoribosylamino) BN1701_RS27545 UMP UTP branched-chain carrier protein]- chorismate bifunctional UDP-N- 10 N,N'- D-ribofuranose asparagine uracil degradation aspartate- amino acid Gly-NH-CH - chorismate reductase: BN1701_RS10680 uracil reductase RibD: ribD trans,octacis-decaprenylphospho- an N -formyl- (2-hydroxyphenyl) DHAP histidinal amino acid L-glutamate-5- Gly-Gly-adenylate 2 chorismate acetylglucosamine 5-amino-6-(5-phospho- coproporphyrinogen I 4-guanidinobutanoate diacetylchitobiose 5-phosphate NADH synthase semialdehyde chorismate BN1701_RS02635 ornithine glyphosate β-D-erythro-pentofuranosid-2-ulose 7,8-dihydrofolate acetate I (reductive) ammonium semialdehyde aminotransferase: C(O)-S-L-cysteine diphosphorylase/ D-ribitylamino)uracil (glutamine- aminotransferase: dehydrogenase: mutase: aroH histidinol BN1701_RS08345 adenylyltransferase/ mutase: aroH carbamoyltransferase: uracil BN1701_RS08345 chorismate mutase: glucosamine-1- hydrogen sulfide L-citrulline hydrolyzing) L-glutamate BN1701_RS28030 chorismate mutase: argF glycine dehydrogenase: hisD glu sulfurtransferase BN1701_RS22860 phosphate N- phosphate acquisition : asnB 2-oxoglutarate glutamine gamma- ile BN1701_RS22860 leu glutamate synthase L-aspartate 4- MoeZ: moeZ prephenate acetyltransferase oxidase [+ 5 isozymes] synthetase: semialdehyde prephenate his large subunit: gltB semialdehyde GlmU: glmU a phosphate ThiO: thiO asn 5,6-dihydrouracil BN1701_RS04600 dehydrogenase: prephenate homoserine prephenate N-acetyl-α-D- monoester glutamate synthase pruA dehydrogenase: bifunctional RNase [+ 4 isozymes] dehydrogenase: dehydratase: glucosamine (aminomethyl) glyoxylate L-threonine dihydropyrimidinase: large subunit: gltB BN1701_RS27795 H/acid phosphatase: BN1701_RS19510 L-alanine pheA 1-phosphate phosphonate biosynthesis hydA glu L-cysteine biosynthesis I [CysO sulfur- 3-(4- BN1701_RS34940 biosynthesis III carrier protein] bifunctional UDP-N- alanine L-homoserine hydroxyphenyl) 3-phenyl-2- acid phosphatase: 3-ureidopropanoate ammonium gln acetylglucosamine L-homoserine racemization L-glutamate pyruvate oxopropanoate BN1701_RS21715 ser cys diphosphorylase/ β biosynthesis III phosphate homoserine kinase: -ureidopropionase: cysteine desulfurase: glucosamine-1- ala BN1701_RS19500 BN1701_RS04460 BN1701_RS06475 phosphate N- O-phospho- alanine racemase: 2-oxoglutarate [+ 2 isozymes] acetyltransferase L-homoserine β BN1701_RS15600 pyridoxal 5'- glutamate synthase tyr phe -alanine ala GlmU: glmU alanine phosphate large subunit: gltB threonine synthase: glu racemase: alr synthase: pdxT pdxS glutamate synthase O-acetyl-L-serine UDP-N-acetyl- BN1701_RS02425 hydrogen sulfide α D-ala [+ 15 isozymes] large subunit: gltB -D-glucosamine Alcohol Degradation threonine synthase: UDP-N-acetylglucosamine glu BN1701_RS19505 1-carboxyvinyltransferase: cysteine synthase: glycerol and glycerophosphodiester degradation BN1701_RS33510 murA ethanol degradation II ethanol degradation I glycerol degradation V thr UDP-N-acetyl-α- glycerol D-glucosamine- ethanol ethanol glycerol cys enolpyruvate zinc-binding alcohol zinc-binding alcohol dehydrogenase: UDP-N- a glycerophosphodiester dehydrogenase: acetylmuramate BN1701_RS00420 BN1701_RS00420 dihydroxyacetone dehydrogenase: glycerol acetaldehyde acetaldehyde BN1701_RS24360 glycerophosphodiester PTS-dependent acetaldehyde UDP-N-acetyl- phosphodiesterase: glycerol dihydroxyacetone dehydrogenase α-D-muramate BN1701_RS09980 kinase kinase (acetylating): [+ 2 isozymes] GlpK: glpK phosphotransferase: acetate BN1701_RS07600 dhaM dhaK [+ 2 isozymes] acetate--CoA UDP-N-acetyl- sn-glycerol DHAP ligase: acs α-D-muramoyl- 3-phosphate acetyl-CoA L-alanyl-γ-D- acetate--CoA glutamyl-meso-2,6- ligase: acs diaminopimelate acetyl-CoA DHAP a branched- a branched- chain chain a reduced an amino amino acid amino acid an amino an amino plastocyanin phosphate phosphate acid acid acid a branched- lipid II (meso an oxidized a basic an an an inorganic an inorganic sn-glycerol an amino an amino a tricarboxylate a tricarboxylate a tricarboxylate a tricarboxylate glutamate glutamate chain sulfate ammonium phosphate a dipeptide a dipeptide a dipeptide diaminopimelate plastocyanin amino acid anion anion a carbohydrate a carbohydrate a carbohydrate a carbohydrate a carbohydrate a carbohydrate a carbohydrate a carbohydrate 3-phosphate acid acid oligopeptide oligopeptide predicted predicted amino acid phosphate containing) ABC ABC predicted predicted predicted predicted predicted transporter transporter ABC ABC ABC ABC ABC FtsW CtaD RS25915 RS05150 RS13755 RS05155 RS05160 RS32635 RS07785 RS16275 RS21615 RS24875 RS03685 of a of a RS05395 RS13520 RS13740 RS07135 RS07955 RS05055 RS05190 RS11415 RS11960 UgpC SulP RS16975 RS25125 RS12835 transporter transporter transporter RS13370 RS32940 RS27930 RS30420 RS31050 transporter transporter branched- branched- of an of an of an of phosphate of phosphate chain chain amino acid amino acid amino acid a branched- a basic an an an inorganic an inorganic amino acid amino acid a carbohydrate a carbohydrate a carbohydrate a carbohydrate a carbohydrate a carbohydrate a carbohydrate a carbohydrate sn-glycerol an amino an amino lipid II (meso a tricarboxylate a tricarboxylate a tricarboxylate a tricarboxylate glutamate glutamate chain sulfate ammonium phosphate a dipeptide a dipeptide a dipeptide O amino acid oligopeptide oligopeptide anion anion 3-phosphate acid acid diaminopimelate 2 amino acid phosphate containing) H O phosphate phosphate an amino an amino an amino 2 a branched- a branched- acid acid acid chain chain amino acid amino acid This diagram was automatically generated by SRI International Pathway Tools version 25.0, authors S. Paley and P.D. Karp.